Список цитирований

Список публикаций, цитирующих продукты Lumiprobe. Публикации можно отсортировать по дате или по продукту.

Сортировка
по дате по продукту

1-Этинилпирен

  1. Vega, B.; Wondraczek, H.; Bretschneider, L.; Näreoja, T.; Fardim, P.; Heinze, T. Preparation of reactive fibre interfaces using multifunctional cellulose derivatives. Carbohydrate Polymers, 2015, 132, 261–273. doi: 10.1016/j.carbpol.2015.05.048

BDP 558/568 активированный эфир

  1. Tabe, H.; Sukenobe, K.; Kondo, T.; Sakurai, A.; Maruo, M.; Shimauchi, A.; Hirano, M.; Uno, S.-N.; Kamiya, M.; Urano, Y.; Matsushita, M.; Fujiyoshi, S. Cryogenic Fluorescence Localization Microscopy of Spectrally Selected Individual FRET Pairs in a Water Matrix. The Journal of Physical Chemistry B, 2018, 122(27), 6906–6911. doi: 10.1021/acs.jpcb.8b03977

BDP 581/591 активированный эфир

  1. Tabe, H.; Sukenobe, K.; Kondo, T.; Sakurai, A.; Maruo, M.; Shimauchi, A.; Hirano, M.; Uno, S.-N.; Kamiya, M.; Urano, Y.; Matsushita, M.; Fujiyoshi, S. Cryogenic Fluorescence Localization Microscopy of Spectrally Selected Individual FRET Pairs in a Water Matrix. The Journal of Physical Chemistry B, 2018, 122(27), 6906–6911. doi: 10.1021/acs.jpcb.8b03977

BDP 630/650 амин

  1. Zhang, Y.; Zhu, X.; Chen, X.; Chen, Q.; Zhou, W.; Guo, Q.; Lu, Y.; Li, C.; Zhang, Y.; Liang, D.; Sun, T.; Wei, X.; Jiang, C. Activated Platelets-Targeting Micelles with Controlled Drug Release for Effective Treatment of Primary and Metastatic Triple Negative Breast Cancer. Advanced Functional Materials, in press. doi: 10.1002/adfm.201806620
  2. Zhang, Y.; Guo, Z.; Cao, Z.; Zhou, W.; Zhang, Y.; Chen, Q.; Lu, Y.; Chen, X.; Guo, Q.; Li, C.; Liang, D.; Sun, T.; Jiang, C. Endogenous albumin-mediated delivery of redox-responsive paclitaxel-loaded micelles for targeted cancer therapy. Biomaterials, 2018, 183, 243–257. doi: 10.1016/j.biomaterials.2018.06.002

BDP 630/650 карбоновая кислота

  1. Mitronova, G.Y.; Lukinavičius, G.; Butkevich, A.N.; Kohl, T.; Belov, V.N.; Lehnart, S.E.; Hell, S.W. High-Affinity Functional Fluorescent Ligands for Human β-Adrenoceptors. Scientific Reports, 2017, 7, 12319. doi: 10.1038/s41598-017-12468-3

BDP FL азид

  1. Nuhn, L.; Boli, E.; Massa, S.; Vandenberghe, I.; Movahedi, K.; Devreese, B.; Van Ginderachter, J.; De Geest, B.G. Targeting protumoral tumor-associated macrophages with nanobody-functionalized nanogels through SPAAC ligation. Bioconjugate Chemistry, 2018, 29(7), 2394–2405. doi: 10.1021/acs.bioconjchem.8b00319

BDP FL активированный эфир

  1. Alferova, V.A.; Shuvalov, M.V.; Suchkova, T.A.; Proskurin, G.V.; Aparin, I.O.; Rogozhin, E.A.; Novikov, R.A.; Solyev, P.N.; Chistov, A.A.; Ustinov, A.V.; Tyurin, A.P.; Korshun, V.A. 4-Chloro-L-kynurenine as fluorescent amino acid in natural peptides. Amino Acids, 2018, 50(12), 1697–1705. doi: 10.1007/s00726-018-2642-3
  2. Poreba, M.; Rut, W.; Vizovisek, M.; Groborz, K.; Kasperkiewicz, P.; Finlay, D.; Vuori, K.; Turk, D.; Turk, B.; Salvesen, G.; Drag, M. Selective imaging of human cathepsin L in breast cancer by fluorescent activity-based probes. Chemical Science, 2018, 9(8), 2113–2129. doi: 10.1039/C7SC04303A
  3. Grube, L.; Dellen, R.; Kruse, F.; Schwender, H.; Stuehler, K.; Poschmann, G. Mining the secretome of C2C12 muscle cells: Data dependent experimental approach to analyze protein secretion using label-free quantification and peptide based analysis. Journal of Proteome Research, 2018, 17(2), 879–890. doi: 10.1021/acs.jproteome.7b00684
  4. Wang, C.; Niederstrasser, H.; Douglas, P.M.; Lin, R.; Jaramillo, J.; Li, Y.; Olswald, N.W.; Zhou, A.; McMillan, E.A.; Mendiratta, S.; Wang, Z.; Zhao, T.; Lin, Z.; Luo, M.; Huang, G.; Brekken, R.A.; Posner, B.A.; MacMillan, J.B.; Gao, J.; White, M.A. Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan. Nature Communications, 2017, 8, 2270. doi: 10.1038/s41467-017-02332-3
  5. Gaspar, I.; Wippich, F.; Ephrussi, A. Enzymatic production of single molecule FISH and RNA capture probes. RNA, 2017, 23(10), 1582–1591. doi: 10.1261/rna.061184.117
  6. Perez-Anes, A.; Szarpak-Jankowska, A.; Jary, D.; Auzély-Velty, R. β-CD-Functionalized Microdevice for Rapid Capture and Release of Bacteria. ACS Applied Materials & Interfaces, 2017, 9(16), 13928–13938. doi: 10.1021/acsami.7b02194
  7. Löschmann, N.; Michaelis, M.; Rothweiler, F.; Voges, Y.; Balónová, B.; Blight, B.A.; Cinatl, J. ABCB1 as predominant resistance mechanism in cells with acquired SNS-032 resistance. Oncotarget, 2016, 7(36), 58051–58064. doi: 10.18632/oncotarget.11160
  8. Wang, C.; Wang, Y.; Li, Y.; Bodemann, B.; Zhao, T.; Ma, X.; Huang, G.; Hu, Z.; DeBerardinis, R.J.; White, M.A.; Gao, J. A nanobuffer reporter library for fine-scale imaging and perturbation of endocytic organelles. Nature Communications, 2015, 6, 8524. doi: 10.1038/ncomms9524

BDP FL алкин

  1. Daryaee, F.; Zhang, Z.; Gogarty, K.R.; Li, Y.; Merino, J.; Fisher, S.L.; Tonge, P.J. A quantitative mechanistic PK/PD model directly connects Btk target engagement and in vivo efficacy. Chemical Science, 2017, 8(5), 3434–3443. doi: 10.1039/c6sc03306g
  2. Kubota, T.; Durek, T.; Dang, B.; Finol-Urdaneta, R.K.; Craik, D.J.; Kent, S.B.H.; French, R.J.; Bezanilla, F.; Correa, A.M. Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET. Proceedings of the National Academy of Sciences of the U.S.A., 2017, 114(10), E1857–1865. doi: 10.1073/pnas.1700453114

BDP FL малеимид

  1. Buecheler, J.W.; Winzer, M.; Tonillo, J.; Weber, C.A.; Gieseler, H. Impact of Payload Hydrophobicity on Stability of Antibody-Drug-Conjugates. Molecular Pharmaceutics, 2018, 15(7), 2656–2664. doi: 10.1021/acs.molpharmaceut.8b00177
  2. Mardirossian, M.; Pérébaskine, N.; Benincasa, M.; Gambato, S.; Hofmann, S.; Huter, P.; Müller, C.; Hilpert, K.; Innis, C.A.; Tossi, A.; Wilson, D.N. The Dolphin Proline-Rich Antimicrobial Peptide Tur1A Inhibits Protein Synthesis by Targeting the Bacterial Ribosome. Cell Chemical Biology, 2018, 25(5), 530–539.e7. doi: 10.1016/j.chembiol.2018.02.004

Cu(II)-TBTA комплекс, 10 мМ в 55% водном ДМСО

  1. Kuznetsov, A.E.; Komarova, N.V.; Kuznetsov, E.V.; Andrianova, M.S.; Grudtsov, V.P.; Rybachek, E.N.; Puchnin, K.V.; Ryazantsev, D.V.; Saurov, A.N. Integration of a field effect transistor-based aptasensor under a hydrophobic membrane for bioelectronic nose applications. Biosensors and Bioelectronics. doi: 10.1016/j.bios.2019.01.013
  2. Elrod, N.R.; Jaworski, E.A.; Ji, P.; Wagner, E.J.; Routh, A. Development of Poly(A)-ClickSeq as a Tool Enabling Simultaneous Genome-wide Poly(A)-site identification and Differential Expression Analysis. Methods, in press. doi: 10.1016/j.ymeth.2019.01.002
  3. Domljanovic, I.; Hansen, A.H.; Hansen, L.H.; Klitgaard, J.K.; Taskova, M.; Astakhova, K. Studies of Impending Oligonucleotide Therapeutics in Simulated Biofluids. Nucleic Acid Therapeutics, 2018, 28(6), 348–356. doi: 10.1089/nat.2017.0704
  4. Schrand, B.; Clark, E.; Levay, A.; Capote, A.R.; Martinez, O.; Brenneman, R.; Castro, I.; Gilboa, E. Hapten-mediated recruitment of polyclonal antibodies to tumors engenders antitumor immunity. Nature Communications, 2018, 9, 3348. doi: 10.1038/s41467-018-05566-x
  5. Surya, S.L.; Long, M.J.C.; Urul, D.A.; Zhao, Y.; Mercer, E.J.; EIsaid, I.M.; Evans, T.; Aye, Y. Cardiovascular Small Heat Shock Protein HSPB7 Is a Kinetically Privileged Reactive Electrophilic Species (RES) Sensor. ACS Chemical Biology, 2018, 13(7), 1824–1831. doi: 10.1021/acschembio.7b00925
  6. Yang, J.; Jiang, Q.; He, L.; Zhan, P.; Liu, Q.; Liu, S.; Fu, M.; Liu, J.; Li, C.; Ding, B. Self-Assembled Double-Bundle DNA Tetrahedron for Efficient Antisense Delivery. ACS Applied Materials & Interfaces, 2018, 10(28), 23693–23699. doi: 10.1021/acsami.8b07889
  7. Long, M.J.C.; Urul, D.A.; Chawla, S.; Lin, H.-Y.; Zhao, Y.; Haegele, J.A.; Wang, Y.; Aye, Y. Precision Electrophile Tagging in Caenorhabditis elegans. Biochemistry, 2018, 57(2), 216–220. doi: 10.1021/acs.biochem.7b00642
  8. Andrianova, M.; Komarova, N.; Grudtsov, V.; Kuznetsov, E.; Kuznetsov, A. Amplified Detection of the Aptamer-Vanillin Complex with the Use of Bsm DNA Polymerase. Sensors, 2018, 18, 49. doi: 10.3390/s18010049
  9. Jaworski, E.; Routh, A. ClickSeq: Replacing Fragmentation and Enzymatic Ligation with Click-Chemistry to Prevent Sequence Chimeras. Methods in Molecular Biology, 2018, 1712, 71–85. doi: 10.1007/978-1-4939-7514-3_6
  10. Kuznetsov, A.; Komarova, N.; Andrianova, M.; Grudtsov, V.; Kuznetsov, E. Aptamer based vanillin sensor using an ion-sensitive field-effect transistor. Microchimica Acta, 2018, 185(1), 3. doi: 10.1007/s00604-017-2586-4
  11. Routh, A.; Ji, P.; Jaworski, E.; Xia, Z.; Li, W.; Wagner, E.J. Poly(A)-ClickSeq: click-chemistry for next-generation 3′-end sequencing without RNA enrichment or fragmentation. Nucleic Acids Research, 2017, 45(12), e112. doi: 10.1093/nar/gkx286
  12. Jaworski, E.; Routh, A. Parallel ClickSeq and Nanopore sequencing elucidates the rapid evolution of defective-interfering RNAs in Flock House virus. PLOS Pathogens, 2017, 13(5), e1006365. doi: 10.1371/journal.ppat.1006365
  13. Taskova, M.; Uhd, J.; Miotke, L.; Kubit, M.; Bell, J.; Ji, H.P.; Astakhova, K. Tandem Oligonucleotide Probe Annealing and Elongation To Discriminate Viral Sequence. Analytical Chemistry, 2017, 89(8), 4363–4366. doi: 10.1021/acs.analchem.7b00646
  14. Taskova, M.; Madsen, C.S.; Jensen, K.J.; Hansen, L.H.; Vester, B.; Astakhova, K. Antisense oligonucleotides internally labeled with peptides show improved target recognition and stability to enzymatic degradation. Bioconjugate Chemistry, 2017, 28(3), 768–774. doi: 10.1021/acs.bioconjchem.6b00567
  15. Long, M.J.C.; Parvez, S.; Zhao, Y.; Surya, S.L.; Wang, Y.; Zhang, S.; Aye, Y. Akt3 is a privileged first responder in isozyme-specific electrophile response. Nature Chemical Biology, 2017, 13(3), 333–338. doi: 10.1038/nchembio.2284
  16. Westergaard Mulberg, M.; Taskova, M.; Thomsen, R.P.; Okholm, A.H.; Kjems, J.; Astakhova, K. New Fluorescent Nanoparticles for Ultrasensitive Detection of Nucleic Acids by Optical Methods. Chembiochem, 2017, 18(16), 1599–1603. doi: 10.1002/cbic.201700125
  17. Shi, P.; Ju, E.; Yan, Z.; Gao, N.; Wang, J.; Hou, J.; Zhang, Y.; Ren, J.; Qu, X. Spatiotemporal control of cell-cell reversible interactions using molecular engineering. Nature communications, 2016, 7, 13088. doi: 10.1038/ncomms13088
  18. Samuelsen, S.V.; Maity, A.; Nybo, M.; Macaubas, C.; Lønstrup, L.; Balboni, I.M.; Mellins, E.D.; Astakhova, K. Novel Phospholipid-Protein Conjugates Allow Improved Detection of Antibodies in Patients with Autoimmune Diseases. PLoS One, 2016, 11(6), e0156125. doi: 10.1371/journal.pone.0156125
  19. Seo, K.-H.; Chu, H.-S.; Yoo, T.H.; Lee, S.-G.; Won, J.-I. Separation efficiency of free-solution conjugated electrophoresis with drag-tags incorporating a synthetic amino acid. Electrophoresis, 2016, 37(5–6), 818–825. doi: 10.1002/elps.201500506
  20. Li, Z.; Liu, Z.; Chen, Z.; Ju, E.; Li, W.; Ren, J.; Qu, X. Bioorthogonal chemistry for selective recognition, separation and killing bacteria over mammalian cells. Chemical Communications, 2016, 52(17), 3482–3485. doi: 10.1039/c5cc10625g
  21. Maity, A.; Macaubas, C.; Mellins, E.; Astakhova, K. Synthesis of Phospholipid-Protein Conjugates as New Antigens for Autoimmune Antibodies. Molecules, 2015, 20(6), 10253–10263. doi: 10.3390/molecules200610253
  22. Abel, G.R.; Cao, B.H.; Hein, J.E.; Ye, T. Covalent, sequence-specific attachment of long {DNA} molecules to a surface using DNA-templated click chemistry. Chemical Communications, 2014, 50(60), 8131–8133. doi: 10.1039/c4cc02900c
  23. Stuart, C.H.; Horita, D.A.; Thomas, M.J.; Salsbury, F.R.; Lively, M.O.; Gmeiner, W.H. Site-Specific DNA-Doxorubicin Conjugates Display Enhanced Cytotoxicity to Breast Cancer Cells. Bioconjugate Chemistry, 2014, 25(2), 406-413. doi: 10.1021/bc4005427
  24. Myung, J.-K.; Banuelos, C.A.; Fernandez, J.G.; Mawji, N.R.; Wang, J.; Tien, A.H.; Yang, Y.C.; Tavakoli, I.; Haile, S.; Watt, K.; McEwan, I.J.; Plymate, S.; Andersen, R.J.; Sadar, M.D. An androgen receptor N-terminal domain antagonist for treating prostate cancer. Journal of Clinical Investigation, 2013, 123(7), 2948–2960. doi: 10.1172/jci66398
  25. Astakhova, I.K.; Hansen, L.H.; Vester, B.; Wengel, J. Peptide-LNA oligonucleotide conjugates. Organic & Biomolecular Chemistry, 2013, 11(25), 4240-4240. doi: 10.1039/c3ob40786a
  26. Lu, X.; Song, C.-X.; Szulwach, K.; Wang, Z.; Weidenbacher, P.; Jin, P.; He, C. Chemical Modification-Assisted Bisulfite Sequencing (CAB-Seq) for 5-Carboxylcytosine Detection in DNA. Journal of the American Chemical Society, 2013, 135(25), 9315-9317. doi: 10.1021/ja4044856
  27. Kovacic, S.; Samii, L.; Woolfson, D.N.; Curmi, P.M.G.; Linke, H.; Forde, N.R.; Blab, G.A. Design and Construction of a One-Dimensional DNA Track for an Artificial Molecular Motor. Journal of Nanomaterials, 2012, 2012, ID-ID 109238. doi: 10.1155/2012/109238
  28. Meimetis, L.G.; Williams, D.E.; Mawji, N.R.; Banuelos, C.A.; Lal, A.A.; Park, J.J.; Tien, A.H.; Fernandez, J.G.; de Voogd, N.J.; Sadar, M.D. et al. Niphatenones, Glycerol Ethers from the Sponge Niphates digitalis Block Androgen Receptor Transcriptional Activity in Prostate Cancer Cells: Structure Elucidation, Synthesis, and Biological Activity . Journal of Medicinal Chemistry, 2012, 55(1), 503-514. doi: 10.1021/jm2014056

Cyanine2 для двумерного электрофореза

  1. Tesarova, B.; Charousova, M.; Dostalova, S.; Bienko, A.; Kopel, P.; Kruszyński, R.; Hynek, D.; Michalek, P.; Eckschlager, T.; Stiborova, M.; Adam, V.; Heger, Z. Folic acid-mediated re-shuttling of ferritin receptor specificity towards a selective delivery of highly cytotoxic nickel(II) coordination compounds. International Journal of Biological Macromolecules, in press. doi: 10.1016/j.ijbiomac.2018.12.128
  2. Laberge, A.; Ayoub, A.; Arif, S.; Larochelle, S.; Garnier, A.; Moulin, V.J. α-2-Macroglobulin induces the shedding of microvesicles from cutaneous wound myofibroblasts. Journal of Cellular Physiology, in press. doi: 10.1002/jcp.27794
  3. Arevalo-Martin, A.; Grassner, L.; Garcia-Ovejero, D.; Paniagua-Torija, B.; Barroso-Garcia, G.; Arandilla, A.G.; Mach, O.; Turrero, A.; Vargas, E.; Alcobendas, M.; Rosell, C.; Alcaraz, M.A.; Ceruelo, S.; Casado, R.;Talavera, F.; Palazón, R.; Sanchez-Blanco, N.; Maier, D.; Esclarin, A.; Molina-Holgado, E. Elevated Autoantibodies in Subacute Human Spinal Cord Injury Are Naturally Occurring Antibodies. Frontiers in Immunology, 2018, 9, 2365. doi: 10.3389/fimmu.2018.02365
  4. Lu, J.; Tang, M.; Liu, Y.; Wang, J.; Wu, Z. Comparative Proteomics of Chromium-Transformed Beas-2B Cells by 2D-DIGE and MALDI-TOF/TOF MS. Biological Trace Element Research, 2018, 185(1), 78–88. doi: 10.1007/s12011-017-1222-9
  5. Tamošiūnė, I.; Stanienė, G.; Haimi, P.; Stanys, V.; Rugienius, R.; Baniulis, D. Endophytic Bacillus and Pseudomonas spp. Modulate Apple Shoot Growth, Cellular Redox Balance, and Protein Expression Under in Vitro Conditions. Frontiers in Plant Science, 2018, 9, 889. doi: 10.3389/fpls.2018.00889
  6. Tsikandelova, R.; Mladenov, P.; Planchon, S.; Kalenderova, S.; Praskova, M.; Mihaylova, Z.; Stanimirov, P.; Mitev, V.; Renaut, J.; Ishkitiev, N. Proteome response of dental pulp cells to exogenous FGF8. Journal of Proteomics, 2018, 183, 14–24. doi: 10.1016/j.jprot.2018.05.004
  7. Jun, D.; Minic, Z.; Bhat, S.V.; Vanderlinde, E.M.; Yost, C.K.; Babu, M.; Dahms, T.E.S. Metabolic Adaptation of a C-Terminal Protease A-Deficient Rhizobium leguminosarum in Response to Loss of Nutrient Transport. Frontiers in Microbiology, 2018, 8, 2617. doi: 10.3389/fmicb.2017.02617
  8. Shields, K.J.; Wu, C. Differential Adipose Tissue Proteomics. Methods in Molecular Biology, 2017, 1788, 243–250. doi: 10.1007/7651_2017_80
  9. Zhao, P.; George, J.V.; Li, B.; Amini, N.; Paluh, J.; Wang, J. Clickable Multifunctional Dumbbell Particles for In Situ Multiplex Single-Cell Cytokine Detection. ACS Applied Materials & Interfaces, 2017, 9(38), 32482–32488. doi: 10.1021/acsami.7b08338
  10. Merjaneh, M.; Langlois, A.; Larochelle, S.; Cloutier, C.B.; Ricard-Blum, S.; Moulin, V.J. Pro-angiogenic capacities of microvesicles produced by skin wound myofibroblasts. Angiogenesis, 2017, 20(3), 385–398. doi: 10.1007/s10456-017-9554-9
  11. Sikorskaite-Gudziuniene, S.; Haimi, P.; Gelvonauskiene, D.; Stanys, V. Nuclear proteome analysis of apple cultivar ‘Antonovka’ accessions in response to apple scab (Venturia inaequalis). European Journal of Plant Pathology, 2017, 148(4), 771–784. doi: 10.1007/s10658-016-1131-3
  12. Bian, Y.; Deng, X.; Yan, X.; Zhou, J.; Yuan, L.; Yan, Y. Integrated proteomic analysis of Brachypodium distachyon roots and leaves reveals a synergistic network in the response to drought stress and recovery. Scientific Reports, 2017, 7, 46183. doi: 10.1038/srep46183
  13. Nemethova, M.; Talian, I.; Danielisova, V.; Tkacikova, S.; Bonova, P.; Bober, P.; Matiasova, M.; Sabo, J.; Burda, J. Delayed bradykinin postconditioning modulates intrinsic neuroprotective enzyme expression in the rat CA1 region after cerebral ischemia: a proteomic study. Metabolic Brain Disease, 2016, 31(6), 1391–1403. doi: 10.1007/s11011-016-9859-1
  14. Lu, J.; Zhou, Z.; Zheng, J.; Zhang, Z.; Lu, R.; Liu, H.; Shi, H.; Tu, Z. 2D-DIGE and MALDI TOF/TOF MS analysis reveal that small GTPase signaling pathways may play an important role in cadmium-induced colon cell malignant transformation. Toxicology and Applied Pharmacology, 2015, 288(1), 106–113. doi: 10.1016/j.taap.2015.07.020
  15. Printz, B.; Guerriero, G.; Sergeant, K.; Renaut, J.; Lutts, S.; Hausman, J.-F. Ups and downs in alfalfa: Proteomic and metabolic changes occurring in the growing stem. Plant Science, 2015, 238, 13–25. doi: 10.1016/j.plantsci.2015.05.014
  16. Ashoub, A.; Baeumlisberger, M.;Neupaertl, M.; Karas, M.; Brüggemann, W. Characterization of common and distinctive adjustments of wild barley leaf proteome under drought acclimation, heat stress and their combination. Plant Molecular Biology, 2015, 87(4–5), 459–471. doi: 10.1007/s11103-015-0291-4
  17. Feret, R.; Lilley, K.S. Protein Profiling Using Two-Dimensional Difference Gel Electrophoresis (2-D DIGE). Current Protocols in Protein Science, 2014, 22.2.1-22.2.17. doi: 10.1002/0471140864.ps2202s75

Cyanine3 азид

  1. Kumar, R.; Welle, A.; Becker, F.; Kopyeva, I.; Lahann, J. Substrate-Independent Micropatterning of Polymer Brushes Based on Photolytic Deactivation of Chemical Vapor Deposition Based Surface-Initiated Atom-Transfer Radical Polymerization Initiator Films. Applied Materials & Interfaces, 2018, 10(38), 31965–31976. doi: 10.1021/acsami.8b11525
  2. Navarro, L.A.; French, D.L.; Zauscher, S. Synthesis of Modular Brush Polymer-Protein Hybrids using Diazotransfer and Copper Click Chemistry. Bioconjugate Chemistry, 2018, 29(8), 2594–2605. doi: 10.1021/acs.bioconjchem.8b00309
  3. Tsai, C.-Y.; Li, C.-W.; Li, J.-R.; Jang, B.-H.; Chen, S.-H. Steroid Probes Conjugated with Protein-Protected Gold Nanocluster: Specific and Rapid Fluorescence Imaging of Steroid Receptors in Target Cells. Journal of Fluorescence, 2016, 26(4), 1239–1248. doi: 10.1007/s10895-016-1811-6
  4. Park, H.; Koo, J.Y.; Srikanth, Y.V.V.; Oh, S.; Lee, J.; Park, J.; Park, S.B. Nonspecific protein labeling of photoaffinity linkers correlates with their molecular shapes in living cells. Chemical Communications, 2016, 52(34), 5828–5831. doi: 10.1039/c6cc01426g
  5. Zilio, C.;Bernardi, A.; Palmioli, A.; Salina, M.; Tagliabue, G.; Buscaglia, M.; Consonni, R.; Chiari, M. New "clickable" polymeric coating for glycan microarrays. Sensors and Actuators B: Chemical, 2015, 215, 412–420. doi: 10.1016/j.snb.2015.03.079
  6. Hong, T.N.; van der Hoorn, R.A.L. DIGE-ABPP by Click Chemistry: Pairwise Comparison of Serine Hydrolase Activities from the Apoplast of Infected Plants. Plant-Pathogen Interactions (Methods in Molecular Biology), 2014, 1127, 183-194. doi: 10.1007/978-1-62703-986-4_15
  7. Kupryushkin, M.S.; Nekrasov, M.D.; Stetsenko, D.A.; Pyshnyi, D.V. Efficient Functionalization of Oligonucleotides by New Achiral Nonnucleosidic Monomers. Organic Letters, 2014, 16(11), 2842-2845. doi: 10.1021/ol500668n
  8. Nienhaus, L.; Gross, D.E.; Xue, Z.; Moore, J.S.; Gruebele, M. Intramolecular energy transfer in a synthetic dendron-based light harvesting system. Journal of Photochemistry and Photobiology A: Chemistry, 2014, 295, 26-33. doi: 10.1016/j.jphotochem.2014.08.014
  9. Palsuledesai, C.C.; Ochocki, J.D.; Markowski, T.W.; Distefano, M.D. A combination of metabolic labeling and 2D-DIGE analysis in response to a farnesyltransferase inhibitor facilitates the discovery of new prenylated proteins. Molecular BioSystems, 2014, 10(5), 1094-1103. doi: 10.1039/c3mb70593e
  10. Astakhova, I.K.; Wengel, J. Interfacing Click Chemistry with Automated Oligonucleotide Synthesis for the Preparation of Fluorescent DNA Probes Containing Internal Xanthene and Cyanine Dyes. Chemistry - a European Journal, 2013, 19(3), 1112-1122. doi: 10.1002/chem.201202621
  11. Paredes, E.; Das, S.R. Click Chemistry for Rapid Labeling and Ligation of RNA. ChemBioChem, 2010, 12(1), 125-131. doi: 10.1002/cbic.201000466

Cyanine3 активированный эфир

  1. Hortelao, A.C.; Carrascosa, R.; Murillo-Cremaes, N.; Patiño, T.; Sanchez, S. Targeting 3D Bladder Cancer Spheroids with Urease-Powered Nanomotors. ACS Nano, in press. doi: 10.1021/acsnano.8b06610
  2. Li, L.; Yang, J.; Soodvilai, S.; Wang, J.; Opanasopit, P.; Kopeček, J. Drug-free albumin-triggered sensitization of cancer cells to anticancer drugs. Journal of Controlled Release, 2019, 293, 84–93. doi: 10.1016/j.jconrel.2018.11.015
  3. Ye, K.; Sinawang, P.D.; Yoong, A.T.I.; Marks, R.S. Photoinducible silane diazirine as an effective crosslinker in the construction of a chemiluminescent immunosensor targeting a model E. coli analyte. Sensors and Actuators B: Chemical, 2018, 256, 234–242. doi: 10.1016/j.snb.2017.10.058
  4. Smith, W.J.; Wang, G.; Gaikwad, H.; Vu, V.P.; Groman, E.; Bourne, D.W.A.; Simberg, D. Accelerated Blood Clearance of Antibodies by Nanosized Click Antidotes. ACS Nano, 2018, 12(12), 12523–12532. doi: 10.1021/acsnano.8b07003
  5. Korzhikov-Vlakh, V.; Averianov, I.; Sinitsyna, E.; Nashchekina, Y.; Polyakov, D.; Guryanov, I.; Lavrentieva, A.; Raddatz, L.; Korzhikova-Vlakh, E.; Scheper, T.; Tennikova, T. Novel Pathway for Efficient Covalent Modification of Polyester Materials of Different Design to Prepare Biomimetic Surfaces. Polymers, 2018, 10(12), 1299. doi: 10.3390/polym10121299
  6. Zhang, L.; Fang, Y.; Li, L.; Yang, J.; Radford, D.C.; Kopeček, J. Human Serum Albumin-Based Drug-Free Macromolecular Therapeutics: Apoptosis Induction by Coiled-Coil-Mediated Cross-Linking of CD20 Antigens on Lymphoma B Cell Surface. Macromolecular Bioscience, 2018, 18(11), e1800224. doi: 10.1002/mabi.201800224
  7. Swaminathan, J.; Boulgakov, A.A.; Hernandez, E.T.; Bardo, A.M.; Bachman, J.L.; Marotta, J.; Johnson, A.M.; Anslyn, E.V.; Marcotte, E.M. Highly parallel single-molecule identification of proteins in zeptomole-scale mixtures. Nature Biotechnology, 2018, 36(11), 1076–1082. doi: 10.1038/nbt.4278
  8. Smith, J.D.; Cardwell, L.N.; Porciani, D.; Nguyen, J.A.; Gallazzi, F.; Tata, R.R.; Burke, D.H.; Daniels, M.A.; Ulery, B. Aptamer-displaying peptide amphiphile micelles as a cell-targeted delivery vehicle of peptide cargoes. Physical Biology, 2018, 15(6), 065006. doi: 10.1088/1478-3975/aadb68
  9. Wu, B.; Zhang, H.; Sun, R.; Peng, S.; Cooperman, B.S.; Goldman, Y.E.; Chen, C. Translocation kinetics and structural dynamics of ribosomes are modulated by the conformational plasticity of downstream pseudoknots. Nucleic Acids Research, 2018, 46(18), 9736–9748. doi: 10.1093/nar/gky636
  10. Delcanale, P.; Miret-Ontiveros, B.; Arista-Romero, M.; Pujals, S.; Albertazzi, L. Nanoscale Mapping Functional Sites on Nanoparticles by Points Accumulation for Imaging in Nanoscale Topography (PAINT). ACS Nano, 2018, 12(8), 7629–7637. doi: 10.1021/acsnano.7b09063
  11. Tridgett, M.; Moore-Kelly, C.; Duprey, J.-L.H.A.; Iturbe, L.O.; Tsang, C.W.; Little, H.A.; Sandhu, S.K.; Hicks, M.R.; Dafforn, T.R.; Rodger, A. Linear dichroism of visible-region chromophores using M13 bacteriophage as an alignment scaffold. RSC Advances, 2018, 8(52), 29535–29543. doi: 10.1039/c8ra05475d
  12. Shvadchak, V.; Zgheib, S.; Basta, B.; Humbert, N.; Langedijk, J.; Morris, M.C.; Ciaco, S.; Maskri, O.; Darlix, J.-L.; Mauffret, O.; Fossé, P.; Réal, E.; Mély, Y. Rationally Designed Peptides as Efficient Inhibitors of Nucleic Acid Chaperone Activity of HIV-1 Nucleocapsid Protein. Biochemistry, 2018, 57(30), 4562–4573. doi: 10.1021/acs.biochem.8b00527
  13. Salinas, C.B.G.; Lu, T.T.-H.; Gabery, S.; Marstal, K.; Alanentalo, T.; Mercer, A.J.; Cornea, A.; Conradsen, K.; Hecksher-Sørensen, J.; Dahl, A.B.; Knudsen, L.B.; Secher, A. Integrated Brain Atlas for Unbiased Mapping of Nervous System Effects Following Liraglutide Treatment. Scientific Reports, 2018, 8, 10310. doi: 10.1038/s41598-018-28496-6
  14. Rho, J.Y.; Brendel, J.C.; MacFarlane, L.R.; Mansfield, E.D.H.; Peltier, R.; Rogers, S.; Hartlieb, M.; Perrier, S. Probing the Dynamic Nature of Self-Assembling Cyclic Peptide–Polymer Nanotubes in Solution and in Mammalian Cells. Advanced Functional Materials, 2018, 28(24), 1704569. doi: 10.1002/adfm.201704569
  15. Tahara, H.; Takabe, K.; Sasaki, Y.; Kasuga, K.; Kawamoto, A.; Koizumi, N.; Nakamura, S. The mechanism of two-phase motility in the spirochete Leptospira: Swimming and crawling. Science Advances, 2018, 4(5), eaar7975. doi: 10.1126/sciadv.aar7975
  16. Larsen, K.P.; Mathiharan, Y.K.; Kappel, K.; Coey, A.T.; Chen, D.-H.; Barrero, D.; Madigan, L.; Puglisi, J.D.; Skiniotis, G.; Puglisi, E.V. Architecture of an HIV-1 reverse transcriptase initiation complex. Nature, 2018, 557, 118–122. doi: 10.1038/s41586-018-0055-9
  17. Poreba, M.; Rut, W.; Vizovisek, M.; Groborz, K.; Kasperkiewicz, P.; Finlay, D.; Vuori, K.; Turk, D.; Turk, B.; Salvesen, G.; Drag, M. Selective imaging of human cathepsin L in breast cancer by fluorescent activity-based probes. Chemical Science, 2018, 9(8), 2113–2129. doi: 10.1039/C7SC04303A
  18. He, H.; Markoutsa, E.; Li, J.; Xu, P. Repurposing Disulfiram for Cancer Therapy via Targeted Nanotechnology through Enhanced Tumor Mass Penetration and Disassembly. Acta Biomaterialia, 2018, 68, 113–124. doi: 10.1016/j.actbio.2017.12.023
  19. Li, L.; Yang, J.; Wang, J.; Kopeček, J. Drug-Free Macromolecular Therapeutics Induce Apoptosis via Calcium Influx and Mitochondrial Signaling Pathway. Macromolecular Bioscience, 2018, 1, 1700196. doi: 10.1002/mabi.201700196
  20. Locke, L.W.; Kothandaraman, S.; Tweedle, M.; Chaney, S.; Wozniak, D.; Schlesinger, L.S. Use of a leukocyte-targeted peptide probe as a potential tracer for imaging the tuberculosis granuloma. Tuberculosis, 2018, 108, 201–210. doi: 10.1016/j.tube.2018.01.001
  21. Sato, S.-I.; Yatsuzuka, K.; Katsuda, Y.; Uesugi, M. Method for Imaging Live-Cell RNA Using an RNA Aptamer and a Fluorescent Probe. Methods in Molecular Biology, 2018, 1649, 305–318. doi: 10.1007/978-1-4939-7213-5_20
  22. Kim, J.-w.; Heu, W.; Jeong, S.; Kim, H.-S. Genetically functionalized ferritin nanoparticles with a high-affinity protein binder for immunoassay and imaging. Analytica Chimica Acta, 2017, 988, 81–88. doi: 10.1016/j.aca.2017.07.060
  23. Zhang, C.; Yang, L.; Ding, Y.; Wang, Y.; Lan, L.; Ma, Q.; Chi, X.; Wei, P.; Zhao, Y.; Steinbüchel, A.; Zhang, H.; Liu, P. Bacterial lipid droplets bind to DNA via an intermediary protein that enhances survival under stress. Nature Communications, 2017, 8, 15979. doi: 10.1038/ncomms15979
  24. Sun, S.; Li, L.; Yang, F.; Wang, X.; Fan, F.; Yang, M.; Chen, C.; Li, X.; Wang, H.-W.; Sui, S.-F. Cryo-EM structures of the ATP-bound Vps4E233Q hexamer and its complex with Vta1 at near-atomic resolution. Nature Communications, 2017, 8, 16064. doi: 10.1038/ncomms16064
  25. Rosier, B.J.H.M.; Cremers, G.A.O.; Engelen, W.; Merkx, M.; Brunsveld, L.; de Greef, T.F.A. Incorporation of native antibodies and Fc-fusion proteins on DNA nanostructures via a modular conjugation strategy. Chemical Communications, 2017, 53, 7393–7396. doi: 10.1039/c7cc04178k
  26. Maity, S.; Hashemi, M.; Lyubchenko, Y.L. Nano-assembly of amyloid β peptide: role of the hairpin fold. Scientific Reports, 2017, 7, 2344. doi: 10.1038/s41598-017-02454-0
  27. Tang, X.-L.; Yuan, C.-H.; Ding, Q.; Zhou, Y.; Pan, Q.; Zhang, X.-L. Selection and identification of specific glycoproteins and glycan biomarkers of macrophages involved in Mycobacterium tuberculosis infection. Tuberculosis, 2017, 104, 95–106. doi: 10.1016/j.tube.2017.03.010
  28. Taskova, M.; Uhd, J.; Miotke, L.; Kubit, M.; Bell, J.; Ji, H.P.; Astakhova, K. Tandem Oligonucleotide Probe Annealing and Elongation To Discriminate Viral Sequence. Analytical Chemistry, 2017, 89(8), 4363–4366. doi: 10.1021/acs.analchem.7b00646
  29. Chen, K.; Guo, L.; Zhang, J.; Chen, Q.; Wang, K.; Li, C.; Li, W.; Qiao, M.; Zhao, X.; Hu, H.; Chen, D. A gene delivery system containing nuclear localization signal: increased nucleus import and transfection efficiency with the assistance of RanGAP1. Acta Biomaterialia, 2017, 48, 215–226. doi: 10.1016/j.actbio.2016.11.004
  30. Shirure, V.S.; George, S.C. Design considerations to minimize the impact of drug absorption in polymer-based organ-on-a-chip platforms. Lab on a Chip, 2017, 17(4), 681–690. doi: 10.1039/c6lc01401a
  31. Lu, K.-Y.; Li, R.; Hsu, C.-H.; Lin, C.-W.; Chou, S.-C.; Tsai, M.-L.; Mi, F.-L. Development of a new type of multifunctional fucoidan-based nanoparticles for anticancer drug delivery. Carbohydrate Polymers, 2017, 165, 410–420. doi: 10.1016/j.carbpol.2017.02.065
  32. Taneja, N.; Zofall, M.; Balachandran, V.; Thillainadesan, G.; Sugiyama, T.; Wheeler, D.; Zhou, M.; Grewal, S.I.S. SNF2 Family Protein Fft3 Suppresses Nucleosome Turnover to Promote Epigenetic Inheritance and Proper Replication. Molecular Cell, 2017, 66(1), 50–62. doi: 10.1016/j.molcel.2017.02.006
  33. Gilbert, T.; Alsop, R.J.; Babi, M.; Moran-Mirabal, J.; Rheinstadter, M.C.; Hoare, T. Nanostructure of Fully Injectable Hydrazone-Thiosuccinimide Interpenetrating Polymer Network Hydrogels Assessed by Small-Angle Neutron Scattering and dSTORM Single-Molecule Fluorescence Microscopy. ACS Applied Materials & Interfaces, 2017, 9(48), 42179–42191. doi: 10.1021/acsami.7b11637
  34. Lin, T.-H.; Lin, C.-H.; Liu, Y.-J.; Huang, C.Y.; Lin, Y.-C.; Wang, S.-K. Controlling Ligand Spacing on Surface: Polyproline-Based Fluorous Microarray as a Tool in Spatial Specificity Analysis and Inhibitor Development for Carbohydrate-Protein Interactions. ACS Applied Materials & Interfaces, 2017, 9(48), 41691–41699. doi: 10.1021/acsami.7b13200
  35. Ramirez, Lisa and Herschkowitz, Jason I. and Wang, Jun. Stand-Sit Microchip for High-Throughput, Multiplexed Analysis of Single Cancer Cells. Scientific Reports, 2016, 6, 32505. doi: 10.1038/srep32505
  36. Hong, W.; Lee, S.; Chang, H.J.; Lee, E.S.; Cho, Y. Multifunctional magnetic nanowires: A novel breakthrough for ultrasensitive detection and isolation of rare cancer cells from non-metastatic early breast cancer patients using small volumes of blood. Biomaterials, 2016, 106, 78–86. doi: 10.1016/j.biomaterials.2016.08.020
  37. Wang, C.; Tang, F.; Wang, X.; Li, L. Synthesis and application of biocompatible gold core-poly-(L-Lysine) shell nanoparticles. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2016, 506, 425–430. doi: 10.1016/j.colsurfa.2016.07.014
  38. Zhong, Q.; Merkel, O.M.; Reineke, J.J.; da Rocha, S.R.P. Effect of the Route of Administration and PEGylation of Poly(amidoamine) Dendrimers on their Systemic and Lung Cellular Biodistribution. Molecular Pharmaceutics, 2016, 13(6), 1866–1878. doi: 10.1021/acs.molpharmaceut.6b00036
  39. Ray, J.; Shin, I.; Ilgu, M.; Bendickson, L.; Gupta, V.; Kraus, G.A.; Nilsen-Hamilton, M. IMAGEtags: Quantifying mRNA Transcription in Real Time with Multiaptamer Reporters. Methods in Enzymology, 2016, 572, 193–213. doi: 10.1016/bs.mie.2016.02.028
  40. Hartley, J.M.; Zhang, R.; Gudheti, M.; Yang, J.; Kopeček, J. Tracking and quantifying polymer therapeutic distribution on a cellular level using 3D dSTORM. Journal of Controlled Release, 2016, 231, 50–59. doi: 10.1016/j.jconrel.2016.02.005
  41. Leenders, J.; Baker, M.B.; Pijpers, I.; Lafleur, R.; Albertazzi, L.; Palmans, A.R.A.; Meijer, E.W. Supramolecular polymerisation in water; elucidating the role of hydrophobic and hydrogen-bond interactions. Soft Matter, 2016, 12, 2887–2893. doi: 10.1039/c5sm02843d
  42. Kijima, S.T.; Hirose, K.; Kong, S.-G.; Wada, M.; Uyeda, T.Q.P. Distinct Biochemical Properties of Arabidopsis thaliana Actin Isoforms. Plant and Cell Physiology, 2016, 57(1), 46–56. doi: 10.1093/pcp/pcv176
  43. Poongavanam, M.-V.; Kisley, L.; Kourentzi, K.; Landes, C.F.; Willson, C. Ensemble and Single-Molecule Biophysical Characterization of D17.4 DNA Aptamer-IgE Interactions. Biochimica et Biophysica Acta, 2016, 1864(1), 154–164. doi: 10.1016/j.bbapap.2015.08.008
  44. Koo, H.; Choi, M.; Kim, E.; Hahn, S.K.; Weissleder, R.; Yun, S.H. Bioorthogonal Click Chemistry-Based Synthetic Cell Glue. Small, 2015, 11(48), 6458–6466. doi: 10.1002/smll.201502972
  45. Albertazzi, L.; van der Veeken, N.; Baker, M.B.; Palmans, A.R.A.; Meijer, E.W. Supramolecular copolymers with stimuli-responsive sequence control. Chemical Communications, 2015, 51(90), 16166–16168. doi: 10.1039/c5cc06951c
  46. Yang, J.; Zhang, R.; Radford, D.C.; Kopeček, J. FRET-trackable biodegradable HPMA copolymer-epirubicin conjugates for ovarian carcinoma therapy. Journal of Controlled Release, 2015, 218, 36–44. doi: 10.1016/j.jconrel.2015.09.045
  47. Søndergaard, S.; Aznauryan, M.; Haustrup, E.K.; Schiøtt, B.; Birkedal, V.; Corry, B. Dynamics of Fluorescent Dyes Attached to G-Quadruplex DNA and their Effect on FRET Experiments. ChemPhysChem, 2015, 16(12), 2562–2570. doi: 10.1002/cphc.201500271
  48. Li, X.-P.; Jing, W.; Sun, J.-J.; Liu, Z.-Y.; Zhang, J.-T.; Sun, W.; Zhu, W.; Fan, Y.-Z. A potential small-molecule synthetic antilymphangiogenic agent norcantharidin inhibits tumor growth and lymphangiogenesis of human colonic adenocarcinomas through blocking VEGF-A,-C,-D/VEGFR-2,-3 "multi-points priming" mechanisms in vitro and ... BMC Cancer, 2015, 15, 527. doi: 10.1186/s12885-015-1521-5
  49. Rammohan, J.; Ruiz Manzano, A.; Garner, A.L.; Stallings, C.L.; Galburt, E.A. CarD stabilizes mycobacterial open complexes via a two-tiered kinetic mechanism. Nucleic Acids Research, 2015, 43(6), 3272–3285. doi: 10.1093/nar/gkv078
  50. Baker, Matthew B. and Albertazzi, Lorenzo and Voets, Ilja K. and Leenders, Christianus M.A. and Palmans, Anja R.A. and Pavan, Giovanni M. and Meijer, E.W. Consequences of chirality on the dynamics of a water-soluble supramolecular polymer. Nature Communications, 2015, 6, 6234. doi: 10.1038/ncomms7234
  51. Choi, E.B.; Choi, J.; Bae, S.R.; Kim, H.-O.; Jang, E.; Kang, B.; Kim, M.-H.; Kim, B.; Suh, J.-S.; Lee, K. et al. Colourimetric redox-polyaniline nanoindicator for in situ vesicular trafficking of intracellular transport. Nano Research, 2015, 8(4), 1169–1179. doi: 10.1007/s12274-014-0597-6
  52. Guenther, D.; Anderson, G.; Karmakar, S.; Anderson, B.A.; Didion, B.A.; Guo, W.; Verstegen, J.; Hrdlicka, P.J. Invader probes: Harnessing the energy of intercalation to facilitate recognition of chromosomal DNA for diagnostic applications. Chemical Science, 2015, 6, 5006–2015. doi: 10.1039/c5sc01238d
  53. Graen, T.M.D.; Hoefling, M.; Grubmüller, H. AMBER-DYES: Characterization of Charge Fluctuations and Force Field Parameterization of Fluorescent Dyes for Molecular Dynamics Simulations. Journal of Chemical Theory and Computation, 2014, 10(12), 5505-5512. doi: 10.1021/ct500869p
  54. Kim, J.; Yang, Y.; Song, S.S.; Na, J.-H.; Oh, K.J.; Jeong, C.; Yu, Y.G.; Shin, Y.-K. Beta-Amyloid Oligomers Activate Apoptotic BAK Pore for Cytochrome c Release. Biophysical Journal, 2014, 107(7), 1601-1608. doi: 10.1016/j.bpj.2014.07.074
  55. Petkau-Milroy, K.; Sonntag, M.; Colditz, A.; Brunsveld, L. Multivalent Protein Assembly Using Monovalent Self-Assembling Building Blocks. International Journal of Molecular Sciences, 2013, 14(10), 21189–21201. doi: 10.3390/ijms141021189
  56. Albertazzi, L.; Martinez-Veracoechea, F.J.; Leenders, C.M.A.; Voets, I.K.; Frenkel, D.; Meijer, E.W. Spatiotemporal control and superselectivity in supramolecular polymers using multivalency. Proceedings of the National Academy of Sciences of the U.S.A., 2013, 110(30), 12203-12208. doi: 10.1073/pnas.1303109110
  57. Cao, Z.; Partyka, K.; McDonald, M.; Brouhard, E.; Hincapie, M.; Brand, R.E.; Hancock, W.S.; Haab, B.B. Modulation of Glycan Detection on Specific Glycoproteins by Lectin Multimerization. Analytical Chemistry, 2013, 85(3), 1689-1698. doi: 10.1021/ac302826a
  58. Haller, A.; Altman, R.B.; Souliere, M.F.; Blanchard, S.C.; Micura, R. Folding and ligand recognition of the TPP riboswitch aptamer at single-molecule resolution. Proceedings of the National Academy of Sciences of the U.S.A., 2013, 110(11), 4188-4193. doi: 10.1073/pnas.1218062110
  59. Kaastrup, K.; Chan, L.; Sikes, H.D. Impact of Dissociation Constant on the Detection Sensitivity of Polymerization-Based Signal Amplification Reactions. Analytical Chemistry, 2013, 85(17), 8055-8060. doi: 10.1021/ac4018988
  60. Gatzogiannis, E.; Chen, Z.; Wei, L.; Wombacher, R.; Kao, Y.-T.; Yefremov, G.; Cornish, V.W.; Min, W. Mapping protein-specific micro-environments in live cells by fluorescence lifetime imaging of a hybrid genetic-chemical molecular rotor tag. Chemical Communications, 2012, 48(69), 8694-8694. doi: 10.1039/c2cc33133k
  61. Kaastrup, K.; Sikes, H.D. Polymerization-based signal amplification under ambient conditions with thirty-five second reaction times. Lab on a Chip, 2012, 12(20), 4055-4055. doi: 10.1039/c2lc40584a

Cyanine3 алкин

  1. Navarro, L.A.; French, D.L.; Zauscher, S. Synthesis of Modular Brush Polymer-Protein Hybrids using Diazotransfer and Copper Click Chemistry. Bioconjugate Chemistry, 2018, 29(8), 2594–2605. doi: 10.1021/acs.bioconjchem.8b00309
  2. Sacoman, J.L.; Dagda, R.Y.; Burnham-Marusich, A.R.; Dagda, R.K.; Berninsone, P.M. Mitochondrial O-GlcNAc transferase (mOGT) regulates mitochondrial structure, function and survival in HeLa cells. Journal of Biological Chemistry, 2017, 292(11), 4499–4518. doi: 10.1074/jbc.M116.726752
  3. Ponomarenko, A.I.; Brylev, V.A.; Sapozhnikova, K.A.; Ustinov, A.V.; Prokhorenko, I.A.; Zatsepin, T.S.; Korshun, V.A. Tetrahedral DNA conjugates from pentaerythritol-based polyazides. Tetrahedron, 2016, 72(19), 2386–2391. doi: 10.1016/j.tet.2016.03.051
  4. Gaitzsch, J.; Delahaye, M.; Poma, A.; Du Prez, F.; Battaglia, G. Comparison of metal free polymer-dye conjugation strategies in protic solvents. Polymer Chemistry, 2016, 7(17), 3046–3055;. doi: 10.1039/c6py00518g
  5. Vanparijs, N.; De Coen, R.; Laplace, D.R.; Louage, B.; Maji, S.; Lybaert, L.; Hoogenboom, R.; De Geest, B. Transiently responsive protein-polymer conjugates via a grafting-from RAFT approach: for intracellular co-delivery of proteins and immune-modulators. Chemical Communications, 2015, 51, 13972–13975. doi: 10.1039/c5cc04809e
  6. Huang, X.; He, J.; Hao, Y.; Ye, M.; Zhang, Q.; Ni, P.; Liu, J. Synthesis of PEGylated brush-type copolymers for a plurality of plug-and-play functions. RSC Advances, 2015, 5(62), 50019–50023. doi: 10.1039/c5ra06484h
  7. Burnham-Marusich, A.R.; Plechaty, A.M.; Berninsone, P.M. Size-matched alkyne-conjugated cyanine fluorophores to identify differences in protein glycosylation. Electrophoresis, 2014, 35(18), 2621-2625. doi: 10.1002/elps.201400241
  8. Hatzenpichler, R.; Scheller, S.; Tavormina, P.L.; Babin, B.M.; Tirrell, D.A.; Orphan, V.J. In situ visualization of newly synthesized proteins in environmental microbes using amino acid tagging and click chemistry. Environmental Microbiology, 2014, 16(8), 2568-2590. doi: 10.1111/1462-2920.12436

Cyanine3 амин

  1. van Herck, S.; Deswarte, K.; Nuhn, L.; Zhong, Z.; Portela Catani, J.P.; Li, Y.; Sanders, N.N.; Lienenklaus, S.; De Koker, S.; Lambrecht, B.N.; David, S.A.; De Geest, B.G. Lymph-Node-Targeted Immune Activation by Engineered Block Copolymer Amphiphiles-TLR7/8 Agonist Conjugates. Journal of the American Chemical Society, 2018, 140, 14300–14307. doi: 10.1021/jacs.8b08595
  2. Lufton, M.; Bustan, O.; Eylon, B.-h.; Shtifman-Segal, E.; Croitoru-Sadger, T.; Shagan, A.; Shabtay-Orbach, A.; Corem-Salkmon, E.; Berman, J.; Nyska, A.; Mizrahi, B. Living Bacteria in Thermoresponsive Gel for Treating Fungal Infections. Advanced Functional Materials, 2018, 28(40), 1801581. doi: 10.1002/adfm.201801581
  3. Huang, D.; Chen, Y.-S.; Green, C.R.; Rupenthal, I.D. Hyaluronic acid coated albumin nanoparticles for targeted peptide delivery in the treatment of retinal ischaemia. Biomaterials, 2018, 168, 10–23. doi: 10.1016/j.biomaterials.2018.03.034
  4. Murata, H.; Carmali, S.; Baker, S.L.; Matyjaszewski, K.; Russell, A.J. Solid-phase synthesis of protein-polymers on reversible immobilization supports. Nature Communications, 2018, 9, 845. doi: 10.1038/s41467-018-03153-8
  5. Huang, D.; Chen, Y.-S.; Xu, Q.; Hanes, J.; Rupenthal, I.D. Effects of enzymatic degradation on dynamic mechanical properties of the vitreous and intravitreal nanoparticle mobility. European Journal of Pharmaceutical Sciences, 2018, 118, 124–133. doi: 10.1016/j.ejps.2018.03.023
  6. Wollhofen, R.; Buchegger, B.; Eder, C.; Jacak, J.; Kreutzer, J.; Klar, T.A. Functional photoresists for sub-diffraction stimulated emission depletion lithography. Optical Materials Express, 2017, 7(7), 2538–2559. doi: 10.1364/ome.7.002538
  7. Wilson, D.R.; Mosenia, A.; Suprenant, M.P.; Upadhya, R.; Routkevitch, D.; Meyer, R.A.; Quinones-Hinojosa, A.; Green, J.J. Continuous Microfluidic Assembly of Biodegradable Poly(beta-amino ester)/DNA Nanoparticles for Enhanced Gene Delivery. Journal of Biomedical Materials Research. Part A, 2017, 105(6), 1813–1825. doi: 10.1002/jbm.a.36033
  8. Guldris, N.; Argibay, B.; Gallo, J.; Iglesias-Rey, R.; Carbó-Argibay, E.; Kolen'ko, Y.V.; Campos, F.; Sobrino, T.; Salonen, L.M.; Bañobre-López, M.; Castillo, J.; Rivas, J. Magnetite Nanoparticles for Stem Cell Labeling with High Efficiency and Long-Term in Vivo Tracking. Bioconjugate Chemistry, 2017, 28(2), 362–370. doi: 10.1021/acs.bioconjchem.6b00522
  9. Zhao, Y.; Houston, Z.H.; Simpson, J.D.; Chen, L.; Fletcher, N.L.; Fuchs, A.V.; Blakey, I.; Thurecht, K.J. Using Peptide Aptamer Targeted Polymers as a Model Nanomedicine for Investigating Drug Distribution in Cancer Nanotheranostics. Molecular Pharmaceutics, 2017, 14(10), 3539–3549. doi: 10.1021/acs.molpharmaceut.7b00560
  10. Guldris, N.; Argibay, B.; Kolen'ko, Y.V.; Carbó-Argibay, E.; Sobrino, T.; Campos, F.; Salonen, L.M.; Bañobre-López, M.; Castillo, J.; Rivas, J. Influence of the Separation Procedure on the Properties of Magnetic Nanoparticles: Gaining in vitro Stability and T1‐T2 Magnetic Resonance Imaging Performance. Journal of Colloid and Interface Science, 2016, 472, 229–236. doi: 10.1016/j.jcis.2016.03.040
  11. Gaitzsch, J.; Delahaye, M.; Poma, A.; Du Prez, F.; Battaglia, G. Comparison of metal free polymer-dye conjugation strategies in protic solvents. Polymer Chemistry, 2016, 7(17), 3046–3055;. doi: 10.1039/c6py00518g
  12. Demillo, V.G.; Zhu, X. Zwitterionic amphiphile coated magnetofluorescent nanoparticles – synthesis, characterization and tumor cell targeting. Journal of Materials Chemistry B, 2015, 3, 8328–8336. doi: 10.1039/C5TB01116G

Cyanine3 гидразид

  1. Zhang, J.; Chetnani, B.; Cormack, E.D.; Alonso, D.; Liu, W.; Mondragon, A.; Fei, J. Specific structural elements of the T-box riboswitch drive the two-step binding of the tRNA ligand. eLife, 2018, 7, e39518. doi: 10.7554/eLife.39518
  2. Cui, Z.; Wu, Y.; Mureev, S.; Alexandrov, K. Oligonucleotide-mediated tRNA sequestration enables one-pot sense codon reassignment in vitro. Nucleic Acids Research, 2018, 46(12), 6387–6400. doi: 10.1093/nar/gky365
  3. Porciani, D.; Cardwell, L.N.; Tawiah, K.d.; Alam, K.K.; Lange, M.J.; Daniels, M.A.; Burke, D.H. Modular cell-internalizing aptamer nanostructure enables targeted delivery of large functional RNAs in cancer cell lines. Nature Communications, 2018, 9(1), 2283. doi: 10.1038/s41467-018-04691-x
  4. Poudyal, R.R.; Nguyen, P.D.M.; Lokugamage, M.P.; Callaway, M.K.; Gavette, J.V.; Krishnamurthy, R.; Burke, D.H. Nucleobase modification by an RNA enzyme. Nucleic Acids Research, 2017, 45(3), 1345–1354. doi: 10.1093/nar/gkw1199
  5. Boone, C.; Grove, R.; Adamcova, D.; Braga, C.; Adamec, J. Revealing oxidative damage to enzymes of carbohydrate metabolism in yeast: An integration of 2D DIGE, quantitative proteomics and bioinformatics. Proteomics, 2016, 16(13), 1889–1903. doi: 10.1002/pmic.201500546

Cyanine3 для двумерного электрофореза

  1. Laberge, A.; Ayoub, A.; Arif, S.; Larochelle, S.; Garnier, A.; Moulin, V.J. α-2-Macroglobulin induces the shedding of microvesicles from cutaneous wound myofibroblasts. Journal of Cellular Physiology, in press. doi: 10.1002/jcp.27794
  2. Malheiros, J.M.; Braga, C.P.; Grove, R.A.; Ribeiro, F.A.; Calkins, C.R.; Adamec, J.; Chardulo, L.A.L. Influence of oxidative damage to proteins on meat tenderness using a proteomics approach. Meat Science, 2019, 148, 64–71. doi: 10.1016/j.meatsci.2018.08.016
  3. Jin, Y.N.; Schlueter, P.J.; Jurisch-Yaksi, N.; Lam, P.-Y.; Jin, S.; Hwang, W.Y.; Yeh, J.-R.J.; Yoshigi, M.; Ong, S.-E.; Schenone, M.; Hartigan, C.R.; Carr, S.A.; Peterson, R.T. Noncanonical translation via deadenylated 3' UTRs maintains primordial germ cells. Nature Chemical Biology, 2018, 14(9), 844–852. doi: 10.1038/s41589-018-0098-0
  4. Lu, J.; Tang, M.; Liu, Y.; Wang, J.; Wu, Z. Comparative Proteomics of Chromium-Transformed Beas-2B Cells by 2D-DIGE and MALDI-TOF/TOF MS. Biological Trace Element Research, 2018, 185(1), 78–88. doi: 10.1007/s12011-017-1222-9
  5. Tamošiūnė, I.; Stanienė, G.; Haimi, P.; Stanys, V.; Rugienius, R.; Baniulis, D. Endophytic Bacillus and Pseudomonas spp. Modulate Apple Shoot Growth, Cellular Redox Balance, and Protein Expression Under in Vitro Conditions. Frontiers in Plant Science, 2018, 9, 889. doi: 10.3389/fpls.2018.00889
  6. Tsikandelova, R.; Mladenov, P.; Planchon, S.; Kalenderova, S.; Praskova, M.; Mihaylova, Z.; Stanimirov, P.; Mitev, V.; Renaut, J.; Ishkitiev, N. Proteome response of dental pulp cells to exogenous FGF8. Journal of Proteomics, 2018, 183, 14–24. doi: 10.1016/j.jprot.2018.05.004
  7. Jun, D.; Minic, Z.; Bhat, S.V.; Vanderlinde, E.M.; Yost, C.K.; Babu, M.; Dahms, T.E.S. Metabolic Adaptation of a C-Terminal Protease A-Deficient Rhizobium leguminosarum in Response to Loss of Nutrient Transport. Frontiers in Microbiology, 2018, 8, 2617. doi: 10.3389/fmicb.2017.02617
  8. Shields, K.J.; Wu, C. Differential Adipose Tissue Proteomics. Methods in Molecular Biology, 2017, 1788, 243–250. doi: 10.1007/7651_2017_80
  9. Zhao, P.; George, J.V.; Li, B.; Amini, N.; Paluh, J.; Wang, J. Clickable Multifunctional Dumbbell Particles for In Situ Multiplex Single-Cell Cytokine Detection. ACS Applied Materials & Interfaces, 2017, 9(38), 32482–32488. doi: 10.1021/acsami.7b08338
  10. Haimi, P.; Vinskiene, J.; Stepulaitiene, I.; Baniulis, D.; Stanienė, G.; Šikšnianienė, J.B.; Rugienius, R. Patterns of low temperature-Induced accumulation of dehydrins in Rosaceae crops — Evidence for post-translational modification in apple. Journal of Plant Physiology, 2017, 218, 175–181. doi: 10.1016/j.jplph.2017.08.008
  11. Merjaneh, M.; Langlois, A.; Larochelle, S.; Cloutier, C.B.; Ricard-Blum, S.; Moulin, V.J. Pro-angiogenic capacities of microvesicles produced by skin wound myofibroblasts. Angiogenesis, 2017, 20(3), 385–398. doi: 10.1007/s10456-017-9554-9
  12. Sikorskaite-Gudziuniene, S.; Haimi, P.; Gelvonauskiene, D.; Stanys, V. Nuclear proteome analysis of apple cultivar ‘Antonovka’ accessions in response to apple scab (Venturia inaequalis). European Journal of Plant Pathology, 2017, 148(4), 771–784. doi: 10.1007/s10658-016-1131-3
  13. Heller, D.; Helmerhorst, E.J.; Oppenheim, F.G. Saliva and Serum Protein Exchange at the Tooth Enamel Surface. Journal of Dental Research, 2017, 96(4), 437–443. doi: 10.1177/0022034516680771
  14. Bian, Y.; Deng, X.; Yan, X.; Zhou, J.; Yuan, L.; Yan, Y. Integrated proteomic analysis of Brachypodium distachyon roots and leaves reveals a synergistic network in the response to drought stress and recovery. Scientific Reports, 2017, 7, 46183. doi: 10.1038/srep46183
  15. Kaux JF, Libertiaux V, Leprince P, Fillet M, Denoel V Wyss C, Lecut C, Gothot A, Le Goff C, Croisier JL, Crielaard JM, Drion P. Eccentric Training for Tendon Healing After Acute Lesion: A Rat Model. The American Journal of Sports Medicine, 2017, 45(6), 1440–1446. doi: 10.1177/0363546517689872
  16. Nemethova, M.; Talian, I.; Danielisova, V.; Tkacikova, S.; Bonova, P.; Bober, P.; Matiasova, M.; Sabo, J.; Burda, J. Delayed bradykinin postconditioning modulates intrinsic neuroprotective enzyme expression in the rat CA1 region after cerebral ischemia: a proteomic study. Metabolic Brain Disease, 2016, 31(6), 1391–1403. doi: 10.1007/s11011-016-9859-1
  17. Boone, C.; Grove, R.; Adamcova, D.; Braga, C.; Adamec, J. Revealing oxidative damage to enzymes of carbohydrate metabolism in yeast: An integration of 2D DIGE, quantitative proteomics and bioinformatics. Proteomics, 2016, 16(13), 1889–1903. doi: 10.1002/pmic.201500546
  18. Bertrand, A.; Bipfubusa, M.; Castonguay, Y.; Rocher, S.; Szopinska-Morawska, A.; Papadopoulos, Y.; Renaut, J. A proteome analysis of freezing tolerance in red clover (Trifolium pratense L.). BMC Plant Biology, 2016, 16, 65. doi: 10.1186/s12870-016-0751-2
  19. Bipfubusa, M.; Rocher, S.; Bertrand, A.; Castonguay, Y.; Renaut, J. Dataset of protein changes induced by cold acclimation in red clover (Trifolium pratense L.) populations recurrently selected for improved freezing tolerance. Data in Brief, 2016, 8, 570–574. doi: 10.1016/j.dib.2016.06.003
  20. Wang, Z.; Zourelias, L.; Wu, C.; Edwards, P.C.; Trombetta, M.; Passineau, M.J. Ultrasound-assisted nonviral gene transfer of AQP1 to the irradiated minipig parotid gland restores fluid secretion. Gene Therapy, 2015, 22, 739–749. doi: 10.1038/gt.2015.36
  21. Lu, J.; Zhou, Z.; Zheng, J.; Zhang, Z.; Lu, R.; Liu, H.; Shi, H.; Tu, Z. 2D-DIGE and MALDI TOF/TOF MS analysis reveal that small GTPase signaling pathways may play an important role in cadmium-induced colon cell malignant transformation. Toxicology and Applied Pharmacology, 2015, 288(1), 106–113. doi: 10.1016/j.taap.2015.07.020
  22. Printz, B.; Guerriero, G.; Sergeant, K.; Renaut, J.; Lutts, S.; Hausman, J.-F. Ups and downs in alfalfa: Proteomic and metabolic changes occurring in the growing stem. Plant Science, 2015, 238, 13–25. doi: 10.1016/j.plantsci.2015.05.014
  23. Ashoub, A.; Baeumlisberger, M.;Neupaertl, M.; Karas, M.; Brüggemann, W. Characterization of common and distinctive adjustments of wild barley leaf proteome under drought acclimation, heat stress and their combination. Plant Molecular Biology, 2015, 87(4–5), 459–471. doi: 10.1007/s11103-015-0291-4
  24. Feret, R.; Lilley, K.S. Protein Profiling Using Two-Dimensional Difference Gel Electrophoresis (2-D DIGE). Current Protocols in Protein Science, 2014, 22.2.1-22.2.17. doi: 10.1002/0471140864.ps2202s75
  25. Molinari, C.E.; Casadio, Y.S.; Hartmann, B.T.; Livk, A.; Bringans, S.; Arthur, P.G.; Hartmann, P.E. Proteome Mapping of Human Skim Milk Proteins in Term and Preterm Milk. Journal of Proteome Research, 2012, 11(3), 1696-1714. doi: 10.1021/pr2008797

Cyanine3 карбоновая кислота

  1. Deshmukh, R.; Biehs, S.-A.; Khwaja, E.; Galfsky, T.; Agarwal, G.S.; Menon, V.M. Long-range resonant energy transfer using optical topological transitions in metamaterials. ACS Photonics, 2018, 5(7), 2737–2741. doi: 10.1021/acsphotonics.8b00484
  2. Soni, K.S.; Lei, F.; Desale, S.S.; Marky, L.A.; Cohen, S.M.; Bronich, T.K. Tuning polypeptide-based micellar carrier for efficient combination therapy of ErbB2-positive breast cancer. Journal of Controlled Release, 2017, 264, 276–287. doi: 10.1016/j.jconrel.2017.08.038
  3. Melle, A.; Balaceanu, A.; Kather, M.; Wu, Y.; Gau, E.; Sun, W.; Huang, X.; Shi, X.; Karperien, M.; Pich, A. Stimuli-Responsive Poly(N}-vinylcaprolactam-co-2-methoxyethyl acrylate) Core-Shell Microgels: Facile Synthesis, Modulation of Surface Properties and Controlled Internalisation into Cells. Journal of Materials Chemistry B, 2016, 4(30), 5127–5137. doi: 10.1039/c6tb01196a
  4. Kwok, S.J.J.; Choi, M.; Bhayana, B.; Zhang, X.; Ran, C.; Yun, S.-H. Two-photon excited photoconversion of cyanine-based dyes. Scientific Reports, 2016, 6, 23866. doi: 10.1038/srep23866
  5. Xue, M.; Wei, W.; Su, Y.; Johnson, D.; Heath, J.R. Supramolecular Probes for Assessing Glutamine Uptake Enable Semi-Quantitative Metabolic Models in Single Cells. Journal of the American Chemical Society, 2016, 138(9), 3085–3093. doi: 10.1021/jacs.5b12187

Cyanine3 малеимид

  1. Gagni, P.; Romanato, A.; Bergamaschi, G.; Bettotti, P.; Vanna, R.; Piotto, C.; Morasso, C.F.; Chiari, M.; Cretich, M.; Gori, A. A self-assembling peptide hydrogel for ultrarapid 3D bioassays. Nanoscale Advances, in press. doi: 10.1039/c8na00158h
  2. Wu, B.; Zhang, H.; Sun, R.; Peng, S.; Cooperman, B.S.; Goldman, Y.E.; Chen, C. Translocation kinetics and structural dynamics of ribosomes are modulated by the conformational plasticity of downstream pseudoknots. Nucleic Acids Research, 2018, 46(18), 9736–9748. doi: 10.1093/nar/gky636
  3. Liu, G.W.; Prossnitz, A.N.; Eng, D.G.; Cheng, Y.; Subrahmanyam, N.; Pippin, J.W.; Lamm, R.J.; Ngambenjawong, C.; Ghandehari, H.; Shankland, S.J.; Pun, S.H. Glomerular disease augments kidney accumulation of synthetic anionic polymers. Biomaterials, 2018, 178, 317–325. doi: 10.1016/j.biomaterials.2018.06.001
  4. Wojcik, F.; Dann, G.P.; Beh, L.Y.; Debelouchina, G.T.; Hofmann, R.; Muir, T.W. Functional crosstalk between histone H2B ubiquitylation and H2A modifications and variants. Nature Communications, 2018, 9, 1394. doi: 10.1038/s41467-018-03895-5
  5. Gadkari, V.V.; Harvey, S.R.; Raper, A.T.; Chu, W.-T.; Wang, J.; Wysocki, V.H.; Suo, Z. Investigation of sliding DNA clamp dynamics by single-molecule fluorescence, mass spectrometry and structure-based modeling. Nucleic Acids Research, 2018, 46(6), 3103–3118. doi: 10.1093/nar/gky125
  6. Raper, A.T.; Stephenson, A.A.; Suo, Z. Functional Insights Revealed by the Kinetic Mechanism of CRISPR/Cas9. Journal of the American Chemical Society, 2018, 140(8), 2971–2984. doi: 10.1021/jacs.7b13047
  7. Condon, S.G.F.; Mahbuba, D.-A.; Armstrong, C.R.; Díaz-Vázquez, G.; Craven, S.J.; LaPointe, L.M.; Khadria, A.S.; Chadda, R.; Crooks, J.A.; Rangarajan, N.; Weibel, D.B.; Hoskins, A.A.; Robertson, J.L.; Cui, Q.; Senes, A. The FtsLB sub-complex of the bacterial divisome is tetramer with an uninterrupted FtsL helix linking the transmembrane and periplasmic regions. Journal of Biological Chemistry, 2018, 293(5), 1623–1641. doi: 10.1074/jbc.RA117.000426
  8. Deyaert, E.; Wauters, L.; Guaitoli, G.; Konijnenberg, A.; Leemans, M.; Terheyden, S.; Petrovic, A.; Gallardo, R.; Nederveen-Schippers, L.M.; Athanasopoulos, P.S.; Pots, H.; Van Haastert, P.J.M.; Sobott, F.; Gloeckner, C.J.; Efremov, R.; Kortholt, A.; Versées, W. A homologue of the Parkinson's disease-associated protein LRRK2 undergoes a monomer-dimer transition during GTP turnover. Nature Communications, 2017, 8(1), 1008. doi: 10.1038/s41467-017-01103-4
  9. Mateju, D.; Franzmann, T.M.; Patel, A.; Kopach, A.; Boczek, E.E.; Maharana, S.; Lee, H.O.; Carra, S.; Hyman, A.A.; Alberti, S. An aberrant phase transition of stress granules triggered by misfolded protein and prevented by chaperone function. The EMBO Journal, 2017, 36(12), 1669–1687. doi: 10.15252/embj.201695957
  10. Maity, S.; Hashemi, M.; Lyubchenko, Y.L. Nano-assembly of amyloid β peptide: role of the hairpin fold. Scientific Reports, 2017, 7, 2344. doi: 10.1038/s41598-017-02454-0
  11. Wang, H.; Wu, J.; Xu, L.; Xie, K.; Chen, C.; Dong, Y. Albumin Nanoparticle Encapsulation of Potent Cytotoxic Therapeutics Shows Sustained Drug Release and Alleviates Cancer Drug Toxicity. Chemical Communications, 2017, 53(17), 2618–2621. doi: 10.1039/c6cc08978j
  12. Maity, S.; Viazovkina, E.; Gall, A.; Lyubchenko, Y.L. Single-molecule probing of amyloid nano-ensembles using the polymer nanoarray approach. Physical Chemistry Chemical Physics, 2017, 19(25), 16387–16394. doi: 10.1039/c7cp02691a
  13. Xue, C.; Whitis, N.R.; Sashital, D.G. Conformational Control of Cascade Interference and Priming Activities in CRISPR Immunity. Molecular Cell, 2016, 64(4), 826–834. doi: 10.1016/j.molcel.2016.09.033
  14. Chiu, H.-Y.; Deng, W.; Engelke, H.; Helma, J.; Leonhardt, H.; Bein, T. Intracellular chromobody delivery by mesoporous silica nanoparticles for antigen targeting and visualization in real time. Scientific Reports, 2016, 6, 25019. doi: 10.1038/srep25019
  15. Gaitzsch, J.; Delahaye, M.; Poma, A.; Du Prez, F.; Battaglia, G. Comparison of metal free polymer-dye conjugation strategies in protic solvents. Polymer Chemistry, 2016, 7(17), 3046–3055;. doi: 10.1039/c6py00518g
  16. Shrivastava, R.; Köster, D.; Kalme, S.; Mayor, S.; Neerathilingam, M. Tailor-made ezrin actin binding domain to probe its interaction with actin in-vitro. PLoS One, 2015, 10(4), e0123428. doi: 10.1371/journal.pone.0123428
  17. Schmidt, W.M.; Lehman, W.; Moore, J.R. Direct observation of tropomyosin binding to actin filaments. Cytoskeleton, 2015, 72(6), 292–303. doi: 10.1002/cm.21225
  18. Guo, Y.; Yuan, H.; Claudio, N.M.; Kura, S.; Shakerdge, N.; Mempel, T.R.; Bacskai, B.J.; Josephson, L. PEG-Like Nanoprobes: Multimodal, Pharmacokinetically and Optically Tunable Nanomaterials. PLoS ONE, 2014, 9(4), e95406. doi: 10.1371/journal.pone.0095406
  19. Graen, T.M.D.; Hoefling, M.; Grubmüller, H. AMBER-DYES: Characterization of Charge Fluctuations and Force Field Parameterization of Fluorescent Dyes for Molecular Dynamics Simulations. Journal of Chemical Theory and Computation, 2014, 10(12), 5505-5512. doi: 10.1021/ct500869p
  20. Schulze, R.J.; Komar, J.; Botte, M.; Allen, W.J.; Whitehouse, S.; Gold, V.A.M.; Lycklama a Nijeholt, J.A.; Huard, K.; Berger, I.; Schaffitzel, C. et al. Membrane protein insertion and proton-motive-force-dependent secretion through the bacterial holo-translocon SecYEG-SecDF-YajC-YidC. Proceedings of the National Academy of Sciences of the U.S.A., 2014, 111(13), 4844-4849. doi: 10.1073/pnas.1315901111

Cyanine3.5 азид

  1. Gaitzsch, J.; Delahaye, M.; Poma, A.; Du Prez, F.; Battaglia, G. Comparison of metal free polymer-dye conjugation strategies in protic solvents. Polymer Chemistry, 2016, 7(17), 3046–3055;. doi: 10.1039/c6py00518g
  2. Astakhova, I.K.; Wengel, J. Interfacing Click Chemistry with Automated Oligonucleotide Synthesis for the Preparation of Fluorescent DNA Probes Containing Internal Xanthene and Cyanine Dyes. Chemistry - a European Journal, 2013, 19(3), 1112-1122. doi: 10.1002/chem.201202621

Cyanine3.5 активированный эфир

  1. Wang, C.; Niederstrasser, H.; Douglas, P.M.; Lin, R.; Jaramillo, J.; Li, Y.; Olswald, N.W.; Zhou, A.; McMillan, E.A.; Mendiratta, S.; Wang, Z.; Zhao, T.; Lin, Z.; Luo, M.; Huang, G.; Brekken, R.A.; Posner, B.A.; MacMillan, J.B.; Gao, J.; White, M.A. Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan. Nature Communications, 2017, 8, 2270. doi: 10.1038/s41467-017-02332-3
  2. Massey, M.; Kim, H.; Conroy, E.M.; Algar, W.R. Expanded Quantum Dot-Based Concentric Förster Resonance Energy Transfer: Adding and Characterizing Energy-Transfer Pathways for Triply Multiplexed Biosensing. The Journal of Physical Chemistry C, 2017, 121(24), 13345–13356. doi: 10.1021/acs.jpcc.7b02739
  3. Wang, C.; Wang, Y.; Li, Y.; Bodemann, B.; Zhao, T.; Ma, X.; Huang, G.; Hu, Z.; DeBerardinis, R.J.; White, M.A.; Gao, J. A nanobuffer reporter library for fine-scale imaging and perturbation of endocytic organelles. Nature Communications, 2015, 6, 8524. doi: 10.1038/ncomms9524
  4. Fu, B.; Flynn, J.D.; Isaacoff, B.P.; Rowland, D.J.; Biteen, J.S. Super-Resolving the Distance-Dependent Plasmon-Enhanced Fluorescence of Single Dye and Fluorescent Protein Molecules. The Journal of Physical Chemistry C, 2015, 119(33), 19350–19358. doi: 10.1021/acs.jpcc.5b05154

Cyanine3.5 карбоновая кислота

  1. Kwok, S.J.J.; Choi, M.; Bhayana, B.; Zhang, X.; Ran, C.; Yun, S.-H. Two-photon excited photoconversion of cyanine-based dyes. Scientific Reports, 2016, 6, 23866. doi: 10.1038/srep23866

Cyanine5 азид

  1. Fu, Y.; Long, M.J.C.; Wisitpitthaya, S.; Inayat, H.; Pierpont, T.M.; Elsaid, I.M.; Bloom, J.C.; Ortega, J.; Weiss, R.S.; Aye, Y. Nuclear RNR-α antagonizes cell proliferation by directly inhibiting ZRANB3. Nature Chemical Biology, 2018, 14(10), 943–954. doi: 10.1038/s41589-018-0113-5
  2. Surya, S.L.; Long, M.J.C.; Urul, D.A.; Zhao, Y.; Mercer, E.J.; EIsaid, I.M.; Evans, T.; Aye, Y. Cardiovascular Small Heat Shock Protein HSPB7 Is a Kinetically Privileged Reactive Electrophilic Species (RES) Sensor. ACS Chemical Biology, 2018, 13(7), 1824–1831. doi: 10.1021/acschembio.7b00925
  3. Owiti, N.; Wei, S.; Bhagwat, A.; Kim, N. Unscheduled DNA synthesis leads to elevated uracil residues at highly transcribed genomic loci in Saccharomyces cerevisiae. PLoS Genetics, 2018, 14(7), e1007516. doi: 10.1371/journal.pgen.1007516
  4. Zemella, A.; Thoring, L.; Hoffmeister, C.; Šamalíková, M.; Ehren, P.; Wüstenhagen, D.A.; Kubick, S. Cell-free protein synthesis as a novel tool for directed glycoengineering of active erythropoietin. Scientific Reports, 2018, 8, 8514. doi: 10.1038/s41598-018-26936-x
  5. Kidwell, C.U.; Su, C.-Y.; Hibi, M.; Moens, C.B. Multiple zebrafish atoh1 genes specify a diversity of neuronal types in the zebrafish cerebellum. Developmental Biology, 2018, 438(1), 44–56. doi: 10.1016/j.ydbio.2018.03.004
  6. Long, M.J.C.; Urul, D.A.; Chawla, S.; Lin, H.-Y.; Zhao, Y.; Haegele, J.A.; Wang, Y.; Aye, Y. Precision Electrophile Tagging in Caenorhabditis elegans. Biochemistry, 2018, 57(2), 216–220. doi: 10.1021/acs.biochem.7b00642
  7. Maudens, P.; Meyer, S.; Seemayer, C.A.; Jordan, O.; Allémann, E. Self-assembled thermoresponsive nanostructures of hyaluronic acid conjugates for osteoarthritis therapy. Nanoscale, 2018, 10(4), 1845–1854. doi: 10.1039/C7NR07614B
  8. Wei, S.; Perera, M.L.W.; Sakhtemani, R.; Bhagwat, A.S. A novel class of chemicals that react with abasic sites in DNA and specifically kill B cell cancers. PLoS One, 2017, 12, e0185010. doi: 10.1371/journal.pone.0185010
  9. Shabanpoor, F.; Hammond, S.M.; Abendroth, F.; Hazell, G.; Wood, M.J.A.; Gait, M.J. Identification of a Peptide for Systemic Brain Delivery of a Morpholino Oligonucleotide in Mouse Models of Spinal Muscular Atrophy. Nucleic Acid Therapeutics, 2017, 27(3), 130–143. doi: 10.1089/nat.2016.0652
  10. Long, M.J.C.; Parvez, S.; Zhao, Y.; Surya, S.L.; Wang, Y.; Zhang, S.; Aye, Y. Akt3 is a privileged first responder in isozyme-specific electrophile response. Nature Chemical Biology, 2017, 13(3), 333–338. doi: 10.1038/nchembio.2284
  11. Cho, W.; Koo, J.Y.; Park, Y.; Oh, K.; Lee, S.; Song, J.-S.; Bae, M.A.; Lim, D.; Lee, D.-S.; Park, S.B:. Treatment of Sepsis Pathogenesis with High Mobility Group Box Protein 1-Regulating Anti-inflammatory Agents. Journal of Medicinal Chemistry, 2017, 60(1), 170–179. doi: 10.1021/acs.jmedchem.6b00954
  12. Westergaard Mulberg, M.; Taskova, M.; Thomsen, R.P.; Okholm, A.H.; Kjems, J.; Astakhova, K. New Fluorescent Nanoparticles for Ultrasensitive Detection of Nucleic Acids by Optical Methods. Chembiochem, 2017, 18(16), 1599–1603. doi: 10.1002/cbic.201700125
  13. Louage, B.; Tack, L.; Wang, Y.; De Geest, B.G. Poly(glycerol sebacate) nanoparticles for encapsulation of hydrophobic anti-cancer drugs. Polymer Chemistry, 2017, 8(34), 5033–5038. doi: 10.1039/c6py02192a
  14. Barsh, G.R.; Isabella, A.J.; Moens, C.B. Vagus Motor Neuron Topographic Map Determined by Parallel Mechanisms of hox5 Expression and Time of Axon Initiation. Current Biology, 2017, 27(24), 3812–3825.e3. doi: 10.1016/j.cub.2017.11.022
  15. Fiacco, S.V.; Kelderhouse, L.E.; Hardy, A.; Peleg, Y.; Hu, B.; Ornelas, A.; Yang, P.; Gammon, S.T.; Howell, S.M.; Wang, P.; Takahashi, T.T.; Millward, S.W.; Roberts, R.W. Directed Evolution of Scanning Unnatural-Protease-Resistant (SUPR) Peptides for in Vivo Applications. Chembiochem, 2016, 17(17), 1643–1651. doi: 10.1002/cbic.201600253
  16. Farzan, V.M.; Aparin, I.O.; Veselova, O.A.; Podkolzin, A.T.; Shipulin, G.A.; Korshun, V.A.; Zatsepin, T.S. Cy5/BHQ dye-quencher pairs in fluorogenic qPCR probes: effects of charge and hydrophobicity. Analytical Methods, 2016, 8(29), 5826–5831. doi: 10.1039/c6ay01304j
  17. Braner, M.; Kollmannsperger, A.; Wieneke, R.; Tampé, R. ’Traceless’ Tracing of Proteins – High-Affinity Trans-Splicing Directed by a Minimal Interaction Pair. Chemical Science, 2016, 7(4), 2646–2652. doi: 10.1039/C5SC02936H
  18. Li, L.; Grausam, K.B.; Wang, J.; Lun, M.P.; Ohli, J.; Lidov, H.G.W.; Calicchio, M.L.; Zeng, E.; Salisbury, J.L.; Wechsler-Reya, R.J.; Lehtinen, M.K.; Schüller, U.; Zhao, H. Sonic Hedgehog promotes proliferation of Notch-dependent monociliated choroid plexus tumour cells. Nature Cell Biology, 2016, 18(4), 418–430. doi: 10.1038/ncb3327
  19. Yoshimatsu, T.; D'Orazi, F.D.; Gamlin, C.R.; Suzuki, S.C.; Suli, A.; Kimelman, D.; Raible, D.W.; Wong, R.O. Presynaptic partner selection during retinal circuit reassembly varies with timing of neuronal regeneration in vivo. Nature Communications, 2016, 7, 10590. doi: 10.1038/ncomms10590
  20. van der Velde, J.H.M.; Oelerich, J.; Huang, J.; Smit, J.H.; Aminian Jazi, A.; Galiani, S.; Kolmakov, K.; Guoridis, G.; Eggeling, C.; Herrmann, A.; Roelfes, G.; Cordes, T. A simple and versatile design concept for fluorophore derivatives with intramolecular photostabilization. Nature Communications, 2016, 7, 10144. doi: 10.1038/ncomms10144
  21. Park, H.; Koo, J.Y.; Srikanth, Y.V.V.; Oh, S.; Lee, J.; Park, J.; Park, S.B. Nonspecific protein labeling of photoaffinity linkers correlates with their molecular shapes in living cells. Chemical Communications, 2016, 52(34), 5828–5831. doi: 10.1039/c6cc01426g
  22. Wei, S.; Shalhout, S.; Ahn, Y.-H.; Bhagwat, A.S. A Versatile New Tool to Quantify Abasic Sites in DNA and Inhibit Base Excision Repair. DNA Repair, 2015, 27, 9–18. doi: doi:10.1016/j.dnarep.2014.12.006
  23. Hong, T.N.; van der Hoorn, R.A.L. DIGE-ABPP by Click Chemistry: Pairwise Comparison of Serine Hydrolase Activities from the Apoplast of Infected Plants. Plant-Pathogen Interactions (Methods in Molecular Biology), 2014, 1127, 183-194. doi: 10.1007/978-1-62703-986-4_15
  24. Nobori, T.; Shiosaki, S.; Mori, T.; Toita, R.; Kim, C.W.; Nakamura, Y.; Kishimura, A.; Niidome, T.; Katayama, Y. Fluorescent Polyion Complex Nanoparticle That Incorporates an Internal Standard for Quantitative Analysis of Protein Kinase Activity. Bioconjugate Chemistry, 2014, 25(5), 869-872. doi: 10.1021/bc500142j
  25. Palsuledesai, C.C.; Ochocki, J.D.; Markowski, T.W.; Distefano, M.D. A combination of metabolic labeling and 2D-DIGE analysis in response to a farnesyltransferase inhibitor facilitates the discovery of new prenylated proteins. Molecular BioSystems, 2014, 10(5), 1094-1103. doi: 10.1039/c3mb70593e
  26. Shabanpoor, F.; Gait, M.J. Development of a general methodology for labelling peptide–morpholino oligonucleotide conjugates using alkyne–azide click chemistry. Chemical Communications, 2013, 49, 10260–10262. doi: 10.1039/c3cc46067c
  27. Astakhova, I.K.; Wengel, J. Interfacing Click Chemistry with Automated Oligonucleotide Synthesis for the Preparation of Fluorescent DNA Probes Containing Internal Xanthene and Cyanine Dyes. Chemistry - a European Journal, 2013, 19(3), 1112-1122. doi: 10.1002/chem.201202621
  28. Kim, J.; Seo, M.-H.; Lee, S.; Cho, K.; Yang, A.; Woo, K.; Kim, H.-S.; Park, H.-S. Simple and Efficient Strategy for Site-Specific Dual Labeling of Proteins for Single-Molecule Fluorescence Resonance Energy Transfer Analysis. Analytical Chemistry, 2013, 85(3), 1468-1474. doi: 10.1021/ac303089v
  29. McGouran, J.F.; Kramer, H.B.; Mackeen, M.M.; di Gleria, K.; Altun, M.; Kessler, B.M. Fluorescence-based active site probes for profiling deubiquitinating enzymes. Organic & Biomolecular Chemistry, 2012, 10(17), 3379-3379. doi: 10.1039/c2ob25258a
  30. Paredes, E.; Das, S.R. Click Chemistry for Rapid Labeling and Ligation of RNA. ChemBioChem, 2010, 12(1), 125-131. doi: 10.1002/cbic.201000466
  31. Ranall, M.; Gabrielli, B.; Gonda, T. Adaptation and validation of DNA synthesis detection by fluorescent dye derivatization for high-throughput screening. BioTechniques, 2010, 48(5), 379-386. doi: 10.2144/000113410

Cyanine5 активированный эфир

  1. Madl, C.M.; LeSavage, B.L.; Dewi, R.E.; Lampe, K.J.; Heilshorn, S.C. Matrix Remodeling Enhances the Differentiation Capacity of Neural Progenitor Cells in 3D Hydrogels. Advanced Science, in press. doi: 10.1002/advs.201801716
  2. Liu, Y.; Li, Q.; Xiong, X.; Zhou, Z. Improved mitochondrial targeting effect of HPMA copolymer by SS20 peptide mediation and nonendocytosis pathway. Journal of Peptide Science, in press. doi: 10.1002/psc.3144
  3. Xiao, C.; Hu, H.; Yang, H.; Li, S.; Zhou, H.; Ruan, J.; Zhu, Y.; Yang, X.; Li, Z. Colloidal hydroxyethyl starch for tumor-targeted platinum delivery. Nanoscale Advances, in press. doi: 10.1039/c8na00271a
  4. Cooper, C.E.; Silkstone, G.G.A.; Simons, M.; Rajagopal, B.; Syrett, N.; Shaik, T.; Gretton, S.; Welbourn, E.; Bülow, L.; Eriksson, N.L.; Ronda, L.; Mozzarelli, A.; Eke, A.; Mathe, D.; Reeder, B.J. Engineering Tyrosine Residues into Hemoglobin Enhances Heme Reduction, Decreases Oxidative Stress and Increases Vascular Retention of a Hemoglobin Based Blood Substitute. Free Radical Biology & Medicine, 2019, 134, 106–118. doi: 10.1016/j.freeradbiomed.2018.12.030
  5. Shi, M.; Chen, B.; Mahajan, D.; Boh, B.K.; Zhou, Y.; Dutta, B.; Tie, H.C.; Sze, S.K.; Wu, G.; Lu, L. Amino acids stimulate the endosome-to-Golgi trafficking through Ragulator and small GTPase Arl5. Nature Communications, 2018, 9, 4987. doi: 10.1038/s41467-018-07444-y
  6. Li, Z.; Behrens, A.M.; Ginat, N.; Tzeng, S.Y.; Lu, X.; Sivan, S.; Langer, R.; Jaklenec, A. Biofilm-Inspired Encapsulation of Probiotics for the Treatment of Complex Infections. Advanced Materials, 2018, 30(51), e1803925. doi: 10.1002/adma.201803925
  7. Liu, Y.; Li, Q.; Xiong, X.; Huang, Y.; Zhou, Z. Enhanced cellular uptake by non-endocytic pathway for tumor therapy. Journal of Materials Chemistry B, 2018, 6(45), 7411–7419. doi: 10.1039/c8tb01698d
  8. Zhang, L.; Fang, Y.; Li, L.; Yang, J.; Radford, D.C.; Kopeček, J. Human Serum Albumin-Based Drug-Free Macromolecular Therapeutics: Apoptosis Induction by Coiled-Coil-Mediated Cross-Linking of CD20 Antigens on Lymphoma B Cell Surface. Macromolecular Bioscience, 2018, 18(11), e1800224. doi: 10.1002/mabi.201800224
  9. Ng, S.; Bennett, N.J.; Schulze, J.; Gao, N.; Rademacher, C.; Derda, R. Genetically-encoded Fragment-based Discovery of Glycopeptide Ligands for DC-SIGN. Bioorganic & Medicinal Chemistry, 2018, 26(19), 5368–5377. doi: 10.1016/j.bmc.2018.08.036
  10. Zhang, J.; Chetnani, B.; Cormack, E.D.; Alonso, D.; Liu, W.; Mondragon, A.; Fei, J. Specific structural elements of the T-box riboswitch drive the two-step binding of the tRNA ligand. eLife, 2018, 7, e39518. doi: 10.7554/eLife.39518
  11. Lee, K.; Yu, Y. Lipid Bilayer Disruption by Amphiphilic Janus Nanoparticles: The Role of Janus Balance. Langmuir, 2018, 34(41), 12387–12393. doi: 10.1021/acs.langmuir.8b02298
  12. Wu, B.; Zhang, H.; Sun, R.; Peng, S.; Cooperman, B.S.; Goldman, Y.E.; Chen, C. Translocation kinetics and structural dynamics of ribosomes are modulated by the conformational plasticity of downstream pseudoknots. Nucleic Acids Research, 2018, 46(18), 9736–9748. doi: 10.1093/nar/gky636
  13. Khang, M.K.; Zhou, J.; Huang, Y.; Hakamivala, A.; Tang, L. Preparation of a novel injectable in situ-gelling nanoparticle with applications in controlled protein release and cancer cell entrapment. RSC Advances, 2018, 8(60), 34625–34633. doi: 10.1039/c8ra06589f
  14. Besford, Q.A.; Ju, Y.; Wang, T.-Y.; Yun, G.; Cherepanov, P.V.; Hagemeyer, C.E.; Cavalieri, F.; Caruso, F. Self-Assembled Metal-Phenolic Networks on Emulsions as Low-Fouling and pH-Responsive Particles. Small, 2018, 14(39), e1802342. doi: 10.1002/smll.201802342
  15. Wang, Y.; Li, L.; Zhao, W.; Dou, Y.; An, H.; Tao, H.; Xu, X.; Jia, Y.; Lu, S.; Zhang, J.; Hu, H. Targeted Therapy of Atherosclerosis by a Broad-Spectrum Reactive Oxygen Species-Scavenging Nanoparticle with Intrinsic Anti-Inflammatory Activity. ACS Nano, 2018, 12(9), 8943–8960. doi: 10.1021/acsnano.8b02037
  16. Gomez, I.J.; Arnaiz, B.; Cacioppo, M.; Arcudi, F.; Prato, M. Nitrogen-doped Carbon Nanodots for bioimaging and delivery of paclitaxel. Journal of Materials Chemistry B, 2018, 6(35), 5540–5548. doi: 10.1039/c8tb01796d
  17. Xu, C.; Wang, Y.; Yu, H.; Tian, H.; Chen, X. Multifunctional Theranostic Nanoparticles Derived from Fruit-Extracted Anthocyanins with Dynamic Disassembly and Elimination Abilities. ACS Nano, 2018, 12(8), 8255–8265. doi: 10.1021/acsnano.8b03525
  18. Tridgett, M.; Moore-Kelly, C.; Duprey, J.-L.H.A.; Iturbe, L.O.; Tsang, C.W.; Little, H.A.; Sandhu, S.K.; Hicks, M.R.; Dafforn, T.R.; Rodger, A. Linear dichroism of visible-region chromophores using M13 bacteriophage as an alignment scaffold. RSC Advances, 2018, 8(52), 29535–29543. doi: 10.1039/c8ra05475d
  19. Lin, P.-Y.; Chiu, Y.-L.; Huang, J.-H.; Chuang, E.-Y.; Mi, F.-L.; Lin, K.-J.; Juang, J.-H.; Sung, H.-W.; Leong, K.W. Oral Nonviral Gene Delivery for Chronic Protein Replacement Therapy. Advanced Science, 2018, 5(8), 1701079. doi: 10.1002/advs.201701079
  20. Barry, R.; John, S.W.; Liccardi, G.; Tenev, T.; Jaco, I.; Chen, C.-H.; Choi, J.; Kasperkiewicz, P.; Fernandes-Alnemri, T.; Alnemri, E.; Drag, M.; Chen, Y.; Meier, P. SUMO-mediated regulation of NLRP3 modulates inflammasome activity. Nature Communications, 2018, 9, 3001. doi: 10.1038/s41467-018-05321-2
  21. Bonnard, T.; Jayapadman, A.; Putri, J.A.; Cui, J.; Ju, Y.; Carmichael, C.; Angelovich, T.A.; Cody, S.H.; French, S.; Pascaud, K.; Pearce, H.A.; Jagdale, S.; Caruso, F.; Hagemeyer, C.E. Low-Fouling and Biodegradable Protein-Based Particles for Thrombus Imaging. ACS Nano, 2018, 12(7), 6988–6996. doi: 10.1021/acsnano.8b02588
  22. Tovar-Herrera, O.E.; Rodríguez, M.; Olarte-Lozano, M.; Sampedro-Guerrero, J.A.; Guerrero, A.; Pinto-Cámara, R.; Alvarado-Affantranger, X.; Wood, C.D.; Moran-Mirabal, J.M.; Pastor, N.; Segovia, L.; Martínez-Anaya, C. Analysis of the Binding of Expansin Exl1, from Pectobacterium carotovorum, to Plant Xylem and Comparison to EXLX1 from Bacillus subtilis. ACS Omega, 2018, 3(6), 7008–7018. doi: 10.1021/acsomega.8b00406
  23. Patiño, T.; Feiner-Gracia, N.; Arqué, X.; Miguel-López, A.; Jannasch, A.; Stumpp, T.; Schäffer, E.; Albertazzi, L.; Sánchez, S. Influence of Enzyme Quantity and Distribution on the Self-Propulsion of Non-Janus Urease-Powered Micromotors. Journal of the American Chemical Society, 2018, 140(25), 7896–7903. doi: 10.1021/jacs.8b03460
  24. Rho, J.Y.; Brendel, J.C.; MacFarlane, L.R.; Mansfield, E.D.H.; Peltier, R.; Rogers, S.; Hartlieb, M.; Perrier, S. Probing the Dynamic Nature of Self-Assembling Cyclic Peptide–Polymer Nanotubes in Solution and in Mammalian Cells. Advanced Functional Materials, 2018, 28(24), 1704569. doi: 10.1002/adfm.201704569
  25. Hu, H.; Wan, J.; Huang, X.; Tang, Y.; Xiao, C.; Xu, H.; Yang, X.; Li, Z. iRGD-decorated reduction-responsive nanoclusters for targeted drug delivery. Nanoscale, 2018, 10(22), 10514–10527. doi: 10.1039/c8nr02534g
  26. Porciani, D.; Cardwell, L.N.; Tawiah, K.d.; Alam, K.K.; Lange, M.J.; Daniels, M.A.; Burke, D.H. Modular cell-internalizing aptamer nanostructure enables targeted delivery of large functional RNAs in cancer cell lines. Nature Communications, 2018, 9(1), 2283. doi: 10.1038/s41467-018-04691-x
  27. Kao, C.-W.; Wu, P.-T.; Liao, M.-Y.; Chung, I.-J.; Yang, K.-C.; Tseng, W.-Y.I. Yu, J. Magnetic Nanoparticles Conjugated with Peptides Derived from Monocyte Chemoattractant Protein-1 as a Tool for Targeting Atherosclerosis. Pharmaceutics, 2018, 10(2), 62. doi: 10.3390/pharmaceutics10020062
  28. Lee, K.; Zhang, L.; Yi, Y.; Wang, X.; Yu, Y. Rupture of Lipid Membranes Induced by Amphiphilic Janus Nanoparticles. ACS Nano, 2018, 12(4), 3646–3657. doi: 10.1021/acsnano.8b00759
  29. Li, L.; Yang, J.; Wang, J.; Kopeček, J. Amplification of CD20 Cross-Linking in Rituximab-Resistant B-Lymphoma Cells Enhances Apoptosis Induction by Drug-Free Macromolecular Therapeutics. ACS Nano, 2018, 12(4), 3658–3670. doi: 10.1021/acsnano.8b00797
  30. Lee, A.; Kim, S.H.; Lee, H.; Kim, B.; Kim, Y.S.; Key, J. Visualization of MMP-2 Activity Using Dual-Probe Nanoparticles to Detect Potential Metastatic Cancer Cells. Nanomaterials, 2018, 8(2), 119. doi: 10.3390/nano8020119
  31. Poreba, M.; Rut, W.; Vizovisek, M.; Groborz, K.; Kasperkiewicz, P.; Finlay, D.; Vuori, K.; Turk, D.; Turk, B.; Salvesen, G.; Drag, M. Selective imaging of human cathepsin L in breast cancer by fluorescent activity-based probes. Chemical Science, 2018, 9(8), 2113–2129. doi: 10.1039/C7SC04303A
  32. Wang, Y.; Qiao, S.-L.; Wang, H. Facile Synthesis of Peptide-Crosslinked Nanogels for Tumor Metastasis Inhibition. ACS Applied Nano Materials, 2018, 1(2), 785–792. doi: 10.1021/acsanm.7b00203
  33. Cheng, T.; Zhang, Y.; Liu, J.; Ding, Y.; Ou, H.; Huang, F.; An, Y.; Liu, Y.; Liu, J.; Shi, L. Ligand-Switchable Micellar Nanocarriers for Prolonging Circulation Time and Enhancing Targeting Efficiency. ACS Applied Materials & Interfaces, 2018, 10(6), 5296–5304. doi: 10.1021/acsami.7b18137
  34. Jeschke, A.; Haas, A. Sequential actions of phosphatidylinositol phosphates regulate phagosome-lysosome fusion. Molecular Biology of the Cell, 2018, 29(4), 452–465. doi: 10.1091/mbc.E17-07-0464
  35. Li, L.; Yang, J.; Wang, J.; Kopeček, J. Drug-Free Macromolecular Therapeutics Induce Apoptosis via Calcium Influx and Mitochondrial Signaling Pathway. Macromolecular Bioscience, 2018, 1, 1700196. doi: 10.1002/mabi.201700196
  36. Wijnands, S.P.W.; Engelen, W.; Lafleur, R.P.M.; Meijer, E.W.; Merkx, M. Controlling protein activity by dynamic recruitment on a supramolecular polymer platform. Nature Communications, 2018, 9, 65. doi: 10.1038/s41467-017-02559-0
  37. Agrawalla, B.K.; Wang, T.; Riegger, A.; Domogalla, M.P.; Steinbrink, K.; Dörfler, T.; Chen, X.; Boldt, F.; Lamla, M.; Michaelis, J.; Kuan, S.L.; Weil, T. Chemoselective Dual and Triple Labelling of Native and Recombinant Proteins. Bioconjugate Chemistry, 2018, 29(1), 29–34. doi: 10.1021/acs.bioconjchem.7b00675
  38. Kim, H.; Shin, K.; Park, O.K.; Choi, D.; Kim, H.D.; Baik, S.; Lee, S.H.; Kwon, S.-H.; Yarema, K.J.; Hong, J.; Hyeon, T.; Hwang, N.S. General and Facile Coating of Single Cells via Mild Reduction. Journal of the American Chemical Society, 2018, 140(4), 1199–1202. doi: 10.1021/jacs.7b08440
  39. Ashcheulova, D.O.; Efimova, L.V.; Lushchyk, A.Y.; Yantsevich, A.V.; Baikov, A.N.; Pershina, A.G. Production of the recombinant antimicrobial peptide UBI18–35 in Escherichia coli. Protein Expression and Purification, 2018, 143, 38–44. doi: 10.1016/j.pep.2017.10.011
  40. Huang, Q.; Li, S.; Ding, Y.; Yin, H.; Wang, L.-H.; Wang, R. Macrocycle-Wrapped Polyethylenimine for Gene Delivery with Reduced Cytotoxicity. Biomaterials Science, 2018, 6(5), 1031–1039. doi: 10.1039/C8BM00022K
  41. Wang, C.; Niederstrasser, H.; Douglas, P.M.; Lin, R.; Jaramillo, J.; Li, Y.; Olswald, N.W.; Zhou, A.; McMillan, E.A.; Mendiratta, S.; Wang, Z.; Zhao, T.; Lin, Z.; Luo, M.; Huang, G.; Brekken, R.A.; Posner, B.A.; MacMillan, J.B.; Gao, J.; White, M.A. Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan. Nature Communications, 2017, 8, 2270. doi: 10.1038/s41467-017-02332-3
  42. Lee, N.K.; Lee, E.J.; Kim, S.; Nam, G.-H.; Kih, M.; Hong, Y.; Jeong, C.; Yang, Y.; Byun, Y.; Kim, I.-S. Ferritin nanocage with intrinsically disordered proteins and affibody: A platform for tumor targeting with extended pharmacokinetics. Journal of Controlled Release, 2017, 267, 172–180. doi: 10.1016/j.jconrel.2017.08.014
  43. Madl, C.M.; LeSavage, B.L.; Dewi, R.E.; Dinh, C.B.; Stowers, R.S.; Khariton, M.; Lampe, K.J.; Nguyen, D.; Chaudhuri, O.; Enejder, A.; Heilshorn, S.C. Maintenance of neural progenitor cell stemness in 3D hydrogels requires matrix remodelling. Nature Materials, 2017, 16(12), 1233–1242. doi: 10.1038/nmat5020
  44. Hu, H.; Xiao, C.; Wu, H.; Li, Y.; Zhou, Q.; Tang, Y.; Yu, C.; Yang, X.; Li, Z. Nanocolloidosomes with Selective Drug Release for Active Tumor-Targeted Imaging-Guided Photothermal/Chemo Combination Therapy. ACS Applied Materials & Interfaces, 2017, 9(48), 42225–42238. doi: 10.1021/acsami.7b14796
  45. Schäfer, O.; Klinker, K.; Braun, L.; Huesmann, D.; Schultze, J.; Koynov, K.; Barz, M. Combining Orthogonal Reactive Groups in Block Copolymers for Functional Nanoparticle Synthesis in a Single Step. ACS Macro Letters, 2017, 6(10), 1140–1145. doi: 10.1021/acsmacrolett.7b00678
  46. Steele, A.N.; Cai, L.; Truong, V.N.; Edwards, B.B.; Goldstone, A.B.; Eskandari, A.; Mitchell, A.C.; Marquardt, L.M.; Foster, A.A.; Cochran, J.R.; Heilshorn, S.C.; Woo, Y.J. A novel protein-engineered hepatocyte growth factor analog released via a shear-thinning injectable hydrogel enhances post-infarction ventricular function. Biotechnology and Bioengineering, 2017, 114(10), 2379–2389. doi: 10.1002/bit.26345
  47. Wang, F.; Sun, W.; Li, L.; Li, L.; Liu, Y.; Zhang, Z.; Huang, Y. Charge-reversible Multi-functional HPMA Copolymers for Mitochondrial Targeting. ACS Applied Materials & Interfaces, 2017, 9(33), 27563–27574. doi: 10.1021/acsami.7b09693
  48. Dou, Y.; Chen, Y.; Zhang, X.; Xu, X.; Chen, Y.; Guo, J.; Zhang, D.; Wang, R.; Li, X.; Zhang, J. Non-proinflammatory and responsive nanoplatforms for targeted treatment of atherosclerosis. Biomaterials, 2017, 143, 93–108. doi: 10.1016/j.biomaterials.2017.07.035
  49. Lin, P.-Y.; Chuang, E.-Y.; Chiu, Y.-H.; Chen, H.-L.; Lin, K.-J.; Juang, J.-H.; Chiang, C.-H.; Mi, F.-L.; Sung, H.-W. Safety and efficacy of self-assembling bubble carriers stabilized with sodium dodecyl sulfate for oral delivery of therapeutic proteins. Journal of Controlled Release, 2017, 259, 168–175. doi: 10.1016/j.jconrel.2016.12.018
  50. Bloch, M.B.D.; Yavin, E.; Nissan, A.; Ariel, I.; Kenett, R.; Brass, D.; Rubinstein, A. The effect of linker type and recognition peptide conjugation chemistry on tissue affinity and cytotoxicity of charged polyacrylamide. Journal of Controlled Release, 2017, 257, 102–117. doi: 10.1016/j.jconrel.2016.06.038
  51. Seeger, C.; Talibov, V.O.; Danielson, U.H. Biophysical analysis of the dynamics of calmodulin interactions with neurogranin and Ca2+/calmodulin-dependent kinase II. Journal of Molecular Recognition, 2017, 30(8), e2621. doi: 10.1002/jmr.2621
  52. Treerattrakoon, K., Chanthima, W.; Apiwat, C.; Dharakul, T.; Bamrungsap, S. Oriented conjugation of antibodies against~the epithelial cell adhesion molecule on fluorescently doped silica nanoparticles for flow-cytometric determination and in vivo imaging of EpCAM, a biomarker for colorectal cancer. Microchimica Acta, 2017, 184(7), 1941–1950. doi: 10.1007/s00604-017-2211-6
  53. Cho, C.-F.; Wolfe, J.M.; Fadzen, C.M.; Calligaris, D.; Hornburg, K.; Chiocca, E.A.; Agar, N.Y.R.; Pentelute, B.L.; Lawler, S.E. Blood-brain-barrier spheroids as an in vitro screening platform for brain-penetrating agents. Nature Communications, 2017, 8, 15623. doi: 10.1038/ncomms15623
  54. Matsuo, Y.; Maurer, S.P.; Surrey, T.; Toda, T. Purification and characterisation of the fission yeast Ndc80 complex. Protein Expression and Purification, 2017, 135, 61–69. doi: 10.1016/j.pep.2017.05.002
  55. Baranova, N.; Loose, M. Single-molecule measurements to study polymerization dynamics of FtsZ-FtsA copolymers. Methods in Cell Biology, 2017, 137, 355–370. doi: 10.1016/bs.mcb.2016.03.036
  56. Zhang, L.; Fang, Y.; Kopeček, J.; Yang, J. A new construct of antibody-drug conjugates for treatment of B-cell non-Hodgkin's lymphomas. European Journal of Pharmaceutical Sciences, 2017, 103, 36–46. doi: 10.1016/j.ejps.2017.02.034
  57. Brillault, L.; Jutras, P.V.; Dashti, N.; Thuenemann, E.C.; Morgan, G.; Lomonossoff, G.P.; Landsberg, M.J.; Sainsbury, F. Engineering Recombinant Virus-like Nanoparticles from Plants for Cellular Delivery. ACS Nano, 2017, 11(4), 3476–3484. doi: 10.1021/acsnano.6b07747
  58. Taskova, M.; Uhd, J.; Miotke, L.; Kubit, M.; Bell, J.; Ji, H.P.; Astakhova, K. Tandem Oligonucleotide Probe Annealing and Elongation To Discriminate Viral Sequence. Analytical Chemistry, 2017, 89(8), 4363–4366. doi: 10.1021/acs.analchem.7b00646
  59. Zhou, H.; Tourkakis, G.; Shi, D.; Kim, D.M.; Zhang, H.; Du, T.; Eades, W.C.; Berezin, M.Y. Cell-free measurements of brightness of fluorescently labeled antibodies. Scientific Reports, 2017, 7, 41819. doi: 10.1038/srep41819
  60. Mottas, I.; Milosevic, A.; Petri-Fink, A.; Rothen-Rutishauser, B.; Bourquin, C. A rapid screening method to evaluate the impact of nanoparticles on macrophages. Nanoscale, 2017, 9(7), 2492–2504. doi: 10.1039/c6nr08194k
  61. Stephen, Z.R.; Gebhart, R.N.; Jeon, M.; Blair, A.A.; Ellenbogen, R.G.; Silber, J.R.; Zhang, M. pH-Sensitive O6-Benzylguanosine Polymer Modified Magnetic Nanoparticles for Treatment of Glioblastomas. Bioconjugate Chemistry, 2017, 28(1), 194–202. doi: 10.1021/acs.bioconjchem.6b00545
  62. Jang, D.; Lee, Y.M.; Lee, J.; Doh, J.; Kim, W.J. Remission of lymphoblastic leukaemia in an intravascular fluidic environment by pliable drug carrier with a sliding target ligand. Scientific Reports, 2017, 7, 40739. doi: 10.1038/srep40739
  63. O'Connell, C.L.; Nooney, R.; McDonagh, C. Cyanine5-doped silica nanoparticles as ultra-bright immunospecific labels for model circulating tumour cells in flow cytometry and microscopy. Biosensors and Bioelectronics, 2017, 91, 190–198. doi: 10.1016/j.bios.2016.12.023
  64. Li, L.; Sun, W.; Li, L.; Liu, Y.; Wu, L.; Wang, F.; Zhou, Z.; Zhang, Z.; Huang, Y. A pH-responsive sequential-disassembly nanohybrid for mitochondrial targeting. Nanoscale, 2017, 9(1), 314–325. doi: 10.1039/c6nr07004c
  65. Bus, T.; Englert, C.; Reifarth, M.; Borchers, P.; Hartlieb, M.; Vollrath, A.; Hoeppener, S.; Traeger, A.; Schubert, U.S. 3rd generation poly(ethylene imine)s for gene delivery. Journal of Materials Chemistry B, 2017, 5(6), 1258–1274. doi: 10.1039/C6TB02592G
  66. Lu, K.-Y.; Li, R.; Hsu, C.-H.; Lin, C.-W.; Chou, S.-C.; Tsai, M.-L.; Mi, F.-L. Development of a new type of multifunctional fucoidan-based nanoparticles for anticancer drug delivery. Carbohydrate Polymers, 2017, 165, 410–420. doi: 10.1016/j.carbpol.2017.02.065
  67. Taneja, N.; Zofall, M.; Balachandran, V.; Thillainadesan, G.; Sugiyama, T.; Wheeler, D.; Zhou, M.; Grewal, S.I.S. SNF2 Family Protein Fft3 Suppresses Nucleosome Turnover to Promote Epigenetic Inheritance and Proper Replication. Molecular Cell, 2017, 66(1), 50–62. doi: 10.1016/j.molcel.2017.02.006
  68. Lunde, N.N.; Haugen, M.H.; Larsen, K.B.B.; Damgaard, I.; Pettersen, S.J.; Kasem, R.; Rut, W.; Drag, M.; Poreba, M.; Johansen, Harald T.; Solberg, R. Glycosylation is important for legumain localization and processing to active forms but not for cystatin E/M inhibitory functions. Biochimie, 2017, 139, 27–37. doi: 10.1016/j.biochi.2017.05.009
  69. Westergaard Mulberg, M.; Taskova, M.; Thomsen, R.P.; Okholm, A.H.; Kjems, J.; Astakhova, K. New Fluorescent Nanoparticles for Ultrasensitive Detection of Nucleic Acids by Optical Methods. Chembiochem, 2017, 18(16), 1599–1603. doi: 10.1002/cbic.201700125
  70. Yang, W.; Xia, Y.; Zou, Y.; Meng, F.; Zhang, J.; Zhong, Z. Bioresponsive Chimaeric Nano-polymersomes Enable Targeted and Efficacious Protein Therapy for Human Lung Cancers in Vivo. Chemistry of Materials, 2017, 29(20), 8757–8765. doi: 10.1021/acs.chemmater.7b02953
  71. Gilbert, T.; Alsop, R.J.; Babi, M.; Moran-Mirabal, J.; Rheinstadter, M.C.; Hoare, T. Nanostructure of Fully Injectable Hydrazone-Thiosuccinimide Interpenetrating Polymer Network Hydrogels Assessed by Small-Angle Neutron Scattering and dSTORM Single-Molecule Fluorescence Microscopy. ACS Applied Materials & Interfaces, 2017, 9(48), 42179–42191. doi: 10.1021/acsami.7b11637
  72. Mendler, C.T.; Feuchtinger, A.; Heid, I.; Aichler, M.; D'Alessandria, C.; Pirsig, S.; Blechert, B.; Wester, H.-J.; Braren, R.; Walch, A.; Skerra, A.; Schwaiger, M. Tumor uptake of anti-CD20 Fabs depends on tumor perfusion. Journal of Nuclear Medicine, 2016, 57(12), 1971–1977. doi: 10.2967/jnumed.116.176784
  73. Li, Y.; Zhao, Q.; Wang, Y.; Man, T.; Zhou, L.; Fang, X.; Pei, H.; Chi, L.; Liu, J. Ultrasensitive Signal-on Detection of Nucleic Acids with Surface-Enhanced Raman Scattering and Exonuclease III Assisted Probe Amplification. Analytical Chemistry, 2016, 88(23), 11684–11690. doi: 10.1021/acs.analchem.6b03267
  74. Xu, X.; Xu, Z.; Liu, J.; Zhang, Z.; Chen, H.; Li, X.; Shi, S. Visual tracing of diffusion and biodistribution for amphiphilic cationic nanoparticles using photoacoustic imaging after ex vivo intravitreal injections. International Journal of Nanomedicine, 2016, 11, 5079–5086. doi: 10.2147/IJN.S109986
  75. Cheng, J.; Feng, S.; Han, S.; Zhang, X.; Chen, Y.; Zhou, X.; Wang, R.; Li, X.; Hu, H.; Zhang, J. Facile Assembly of Cost-Effective and Locally Applicable or Injectable Nanohemostats for Hemorrhage Control. ACS Nano, 2016, 10(11), 9957&ndash9973. doi: 10.1021/acsnano.6b04124
  76. Xiao, F.; Li, G.; Wu, Y.; Chen, Q.; Wu, Z.; Yu, R. Label-Free Photonic Crystal-Based β-Lactamase Biosensor for β-Lactam Antibiotic and β-Lactamase Inhibitor. Analytical Chemistry, 2016, 88(18), 9207–9212. doi: 10.1021/acs.analchem.6b02457
  77. Zhang, Q.; Tao, H.; Lin, Y.; Hu, Y.; An, H.; Zhang, D.; Feng, S.; Hu, H.; Wang, R.; Li, X.; Zhang, J. A superoxide dismutase/catalase mimetic nanomedicine for targeted therapy of inflammatory bowel disease. Biomaterials, 2016, 105, 206–221. doi: 10.1016/j.biomaterials.2016.08.010
  78. Feng, S.; Hu, Y.; Peng, S.; Han, S.; Tao, H.; Zhang, Q.; Xu, X.; Zhang, J.; Hu, H. Nanoparticles responsive to the inflammatory microenvironment for targeted treatment of arterial restenosis. Biomaterials, 2016, 105, 167–184. doi: 10.1016/j.biomaterials.2016.08.003
  79. Chen, K.; Chen, Q.; Wang, K.; Zhu, J.; Li, W.; Li, W.; Qiu, L.; Guan, G.; Qiao, M.; Zhao, X.; Hu, H.; Chen, D. Synthesis and characterization of a PAMAM-OH derivative containing an acid-labile β-thiopropionate bond for gene delivery. International Journal of Pharmaceutics, 2016, 509(1–2), 314–327. doi: 10.1016/j.ijpharm.2016.05.060
  80. Wu, F.; Liu, C.; Chen, Y.; Yang, S.; Xu, J.; Huang, R.; Wang, X.; Li, M.; Liu, W.; Mao, W.; Zhou, X. Visualization of G-quadruplexes in gel and in live cells by a near-infrared fluorescent probe. Sensors and Actuators B: Chemical, 2016, 236, 268–275. doi: 10.1016/j.snb.2016.05.162
  81. Wilkinson, N.; Metaxas, A.; Ruud, E.; Raethke, E.; Wickramaratne, S.; Reineke, T.M.; Dutcher, C.S. Internal structure visualization of polymer – clay flocculants using fluorescence. Colloids and Interface Science Communications, 2016, 10–11, 1–5. doi: 10.1016/j.colcom.2016.03.002
  82. Ray, J.; Shin, I.; Ilgu, M.; Bendickson, L.; Gupta, V.; Kraus, G.A.; Nilsen-Hamilton, M. IMAGEtags: Quantifying mRNA Transcription in Real Time with Multiaptamer Reporters. Methods in Enzymology, 2016, 572, 193–213. doi: 10.1016/bs.mie.2016.02.028
  83. Hartley, J.M.; Zhang, R.; Gudheti, M.; Yang, J.; Kopeček, J. Tracking and quantifying polymer therapeutic distribution on a cellular level using 3D dSTORM. Journal of Controlled Release, 2016, 231, 50–59. doi: 10.1016/j.jconrel.2016.02.005
  84. Xu, X.; Li, L.; Zhou, Z.; Sun, W.; Huang, Y. Dual-pH responsive micelle platform for co-delivery of axitinib and doxorubicin. International Journal of Pharmaceutics, 2016, 507(1–2), 50–60. doi: 10.1016/j.ijpharm.2016.04.060
  85. Tran, T.-H.; Krishnan, S.; Amiji, M.M. MicroRNA-223 Induced Repolarization of Peritoneal Macrophages Using CD44 Targeting Hyaluronic Acid Nanoparticles for Anti-Inflammatory Effects. PLoS One, 2016, 11(5), e0152024. doi: 10.1371/journal.pone.0152024
  86. Liu, C.; Stonestrom, A.J.; Christian, T.; Yong, J.; Takase, R.; Hou, Y.-M.; Yang, X. Molecular Basis and Consequences of the Cytochrome c-tRNA Interaction. Journal of Biological Chemistry, 2016, 291(19), 10426–10436. doi: 10.1074/jbc.M115.697789
  87. Li, L.; Sun, W.; Zhang, Z.; Huang, Y. Time-staggered delivery of docetaxel and H1S6A,F8A peptide for sequential dual-strike chemotherapy through tumor priming and nuclear targeting. Journal of Controlled Release, 2016, 232, 62–74. doi: 10.1016/j.jconrel.2016.04.021
  88. Leenders, J.; Baker, M.B.; Pijpers, I.; Lafleur, R.; Albertazzi, L.; Palmans, A.R.A.; Meijer, E.W. Supramolecular polymerisation in water; elucidating the role of hydrophobic and hydrogen-bond interactions. Soft Matter, 2016, 12, 2887–2893. doi: 10.1039/c5sm02843d
  89. Liu, X.; Zhang, P.; He, D:; Rödl, W.; Preiß, T.; Rädler, J.O.; Wagner, E.; Lächelt, U. pH-reversible cationic RNase A conjugates for enhanced cellular delivery and tumor cell killing. Biomacromolecules, 2016, 17(1), 173–182. doi: 10.1021/acs.biomac.5b01289
  90. Schelpe, J.; Monté, D.; Dewitte, F.; Sixma, T.K.; Rucktooa, P. Structure of UBE2Z Enzyme Provides Functional Insight into Specificity in the FAT10 Protein Conjugation Machinery. Journal of Biological Chemistry, 2016, 291(2), 630–639. doi: 10.1074/jbc.M115.671545
  91. He, H.; Altomare, D.; Ozer, U.; Xu, H.; Creek, K.; Chen, H.; Xu, P. Cancer cell-selective killing polymer/copper combination. Biomaterials Science, 2016, 4(1), 115–120. doi: 10.1039/c5bm00325c
  92. van der Velde, J.H.M.; Oelerich, J.; Huang, J.; Smit, J.H.; Aminian Jazi, A.; Galiani, S.; Kolmakov, K.; Guoridis, G.; Eggeling, C.; Herrmann, A.; Roelfes, G.; Cordes, T. A simple and versatile design concept for fluorophore derivatives with intramolecular photostabilization. Nature Communications, 2016, 7, 10144. doi: 10.1038/ncomms10144
  93. Poolman, J.; Maity, C.; Boekhoven, J.; van der Mee, L.; le Sage, V.; Groenewold, M.; van Kasteren, S.; Versluis, F.; van Esch, J.; Eelkema, R. A toolbox for controlling the properties and functionalisation of hydrazone-based supramolecular hydrogels. Journal of Materials Chemistry B, 2016, 4, 852–858. doi: 10.1039/C5TB01870F
  94. Stephen, Z.; Dayringer, C.; Lim, J.; Revia, R.; Halbert, M.; Jeon, M.; Bakthavatsalam, A.; Ellenbogen, R.G.; Zhang, M. An Approach to Rapid Synthesis and Functionalization of Iron Oxide Nanoparticles for High Gene Transfection. ACS Applied Materials & Interfaces, 2016, 8(10), 6320–6328. doi: 10.1021/acsami.5b10883
  95. Horning, D.P.; Joyce, G.F. Amplification of RNA by an RNA polymerase ribozyme. Proceedings of the National Academy of Sciences of the United States of America, 2016, 113(35), 9786–9791. doi: 10.1073/pnas.1610103113
  96. Matsuo, Y.; Maurer, S.P.; Yukawa, M.; Zakian, S.; Singleton, M.R.; Surrey, T.; Toda, T. An unconventional interaction between Dis1/TOG and Mal3/EB1 promotes the fidelity of chromosome segregation. Journal of Cell Science, 2016, 129(24), 4592–4606. doi: 10.1242/jcs.197533
  97. Zhang, Rui and Yang, Jiyuan and Chu, Te-Wei and Hartley, Jonathan M. and Kopeček, Jindřich. Multimodality Imaging of Coiled-Coil Mediated Self-Assembly in a "Drug-Free" Therapeutic System. Advanced Healthcare Materials, 2015, 4(7), 1054–1065. doi: 10.1002/adhm.201400679
  98. Evans, L.E.; Cheeseman, M.D.; Yahya, N.; Jones, K. Investigating Apoptozole as a Chemical Probe for HSP70 Inhibition. PLoS One, 2015, 10(10), e0140006. doi: 10.1371/journal.pone.0140006
  99. Chu, D.; Gao, J.; Wang, Z. Neutrophil-Mediated Delivery of Therapeutic Nanoparticles across Blood Vessel Barrier for Treatment of Inflammation and Infection. ACS Nano, 2015, 9(12), 11800–11811. doi: 10.1021/acsnano.5b05583
  100. Albertazzi, L.; van der Veeken, N.; Baker, M.B.; Palmans, A.R.A.; Meijer, E.W. Supramolecular copolymers with stimuli-responsive sequence control. Chemical Communications, 2015, 51(90), 16166–16168. doi: 10.1039/c5cc06951c
  101. Yang, J.; Zhang, R.; Radford, D.C.; Kopeček, J. FRET-trackable biodegradable HPMA copolymer-epirubicin conjugates for ovarian carcinoma therapy. Journal of Controlled Release, 2015, 218, 36–44. doi: 10.1016/j.jconrel.2015.09.045
  102. Wang, C.; Wang, Y.; Li, Y.; Bodemann, B.; Zhao, T.; Ma, X.; Huang, G.; Hu, Z.; DeBerardinis, R.J.; White, M.A.; Gao, J. A nanobuffer reporter library for fine-scale imaging and perturbation of endocytic organelles. Nature Communications, 2015, 6, 8524. doi: 10.1038/ncomms9524
  103. Vanparijs, N.; De Coen, R.; Laplace, D.R.; Louage, B.; Maji, S.; Lybaert, L.; Hoogenboom, R.; De Geest, B. Transiently responsive protein-polymer conjugates via a grafting-from RAFT approach: for intracellular co-delivery of proteins and immune-modulators. Chemical Communications, 2015, 51, 13972–13975. doi: 10.1039/c5cc04809e
  104. Klykov, O.; Weller, M.G. Quantification of N-hydroxysuccinimide and N-hydroxysulfosuccinimide by hydrophilic interaction chromatography (HILIC). Analytical Methods, 2015, 7, 6443–6448. doi: 10.1039/c5ay00042d
  105. Shi, Q.; Zhang, L.; Liu, M.; Zhang, X.; Zhang, X.; Xu, X.; Chen, S.; Li, X.; Zhang, J. Reversion of multidrug resistance by a pH-responsive cyclodextrin-derived nanomedicine in drug resistant cancer cells. Biomaterials, 2015, 67, 169–182. doi: 10.1016/j.biomaterials.2015.07.023
  106. Chen, L.; An, H.; Doyle, P.S. Synthesis of non-spherical microcapsules through controlled polyelectrolyte coating of hydrogel templates. Langmuir, 2015, 31(33), 9228–9235. doi: 10.1021/acs.langmuir.5b02200
  107. Li, L.; Sun, W.; Zhong, J.; Yang, Qi.; Zhu, X.; Zhou, Z.; Zhang Z.; Huang, Y. Multistage Nanovehicle Delivery System Based on Stepwise Size Reduction and Charge Reversal for Programmed Nuclear Targeting of Systemically Administered Anticancer Drugs. Advanced Functional Materials, 2015, 25(26), 4101–4113. doi: 10.1002/adfm.201501248
  108. Baker, Matthew B. and Albertazzi, Lorenzo and Voets, Ilja K. and Leenders, Christianus M.A. and Palmans, Anja R.A. and Pavan, Giovanni M. and Meijer, E.W. Consequences of chirality on the dynamics of a water-soluble supramolecular polymer. Nature Communications, 2015, 6, 6234. doi: 10.1038/ncomms7234
  109. Unciti-Broceta, J.D.; Cano-Cortés, V.; Altea-Manzano, P.; Pernagallo, S.; Díaz-Mochón, J.J.; Sánchez-Martín, R.M. Number of Nanoparticles per Cell through a Spectrophotometric Method – A key parameter to Assess Nanoparticle-based Cellular Assays. Scientific Reports, 2015, 5, 10091. doi: 10.1038/srep10091
  110. Medina, S.H.; Schneider, J.P. Cancer cell surface induced peptide folding allows intracellular translocation of drug. Journal of Controlled Release, 2015, 209, 317–326. doi: 10.1016/j.jconrel.2015.05.267
  111. Pereira, P.M.; Almada, P.; Henriques, R. High-content 3D multicolor super-resolution localization microscopy. Methods in Cell Biology, 2015, 125, 95–117. doi: 10.1016/bs.mcb.2014.10.004
  112. Chiang, W.-L.; Lin, T.-T.; Sureshbabu, R.; Chia, W.-T.; Hsiao, H.-C.; Liu, H.-Y.; Yang, C.-M.; Sung, H.-W. A rapid drug release system with a NIR light-activated molecular switch for dual-modality photothermal/antibiotic treatments of subcutaneous abscesses. Journal of Controlled Release, 2015, 199, 53–62. doi: 10.1016/j.jconrel.2014.12.011
  113. Geertsema, H.J.; Duderstadt, K.E.; van Oijen, A.M. Single-molecule observation of prokaryotic DNA replication. Methods in Molecular Biology, 2015, 1300, 219–238. doi: 10.1007/978-1-4939-2596-4_14
  114. Nooney, R.; O’Connell, C.; Roy, S.; Boland, K.; Keegan, G.; Kelleher, S.; Daniels, S.; McDonagh, C. Synthesis and characterisation of far-red fluorescent cyanine dye doped silica nanoparticles using a modified microemulsion method for application in bioassays. Sensors and Actuators B: Chemical, 2015, 221, 470–479. doi: 10.1016/j.snb.2015.06.117
  115. Zhang, Z.; Kenny, S.J.; Hauser, M.; Li, W.; Xu, K. Ultrahigh-throughput single-molecule spectroscopy and spectrally resolved super-resolution microscopy. Nature Methods, 2015, 12(10), 935–938. doi: 10.1038/nmeth.3528
  116. Chen, K.; Xu, X.; Guo, J.W.; Zhang, X.; Han, S.; Wang, R.; Li, X.; Zhang, J. Enhanced Intracellular Delivery and Tissue Retention of Nanoparticles by Mussel-Inspired Surface Chemistry. Biomacromolecules, 2015, 16(11), 3574–3583. doi: 10.1021/acs.biomac.5b01056
  117. Dogandzhiyski, P.; Ghidini, A.; Danneberg, F.; Strömberg, R.; Göbel, M.W. Studies on Tris(2-aminobenzimidazole)-PNA Based Artificial Nucleases: A Comparison of Two Analytical Techniques. Bioconjugate Chemistry, 2015, 26(12), 2514–2519. doi: 10.1021/acs.bioconjchem.5b00534
  118. Bird, G.H., Boyapalle, S.; Wong, T.; Opoku-Nsiah, K.; Bedi, R.; Crannell, W.C.; Perry, A.F.; Nguyen, H.; Sampayo, V.; Devareddy, A.; Mohapatra, S.; Mohapatra S.S.; Walensky, L.D. Mucosal delivery of a double-stapled {RS}V peptide prevents nasopulmonary infection. Journal of Clinical Investigation, 2014, 124(5), 2113–2124. doi: 10.1172/jci71856
  119. Basu, R.; Lai, L.-T.; Meng, Z.; Wu, J.; Shao, F.; Zhang, L.-F. Using Amino-Labeled Nucleotide Probes for Simultaneous Single Molecule RNA-DNA FISH. PLoS ONE, 2014, 9(9), e107425. doi: 10.1371/journal.pone.0107425
  120. Bříza, T.; Rimpelová, S.; Králová, J.; Záruba, K.; Kejík, Z.; Ruml, T.; Martásek, P.; Král, V. Pentamethinium fluorescent probes: The impact of molecular structure on photophysical properties and subcellular localization. Dyes and Pigments, 2014, 107, 51-59. doi: 10.1016/j.dyepig.2013.12.021
  121. Bamrungsap, S.; Apiwat, C.; Chantima, W.; Dharakul, T.; Wiriyachaiporn, N. Rapid and sensitive lateral flow immunoassay for influenza antigen using fluorescently-doped silica nanoparticles. Microchimica Acta, 2014, 181(1–2), 223-230. doi: 10.1007/s00604-013-1106-4
  122. Duellberg, C.; Trokter, M.; Jha, R.; Sen, I.; Steinmetz, M.O.; Surrey, T. Reconstitution of a hierarchical +TIP interaction network controlling microtubule end tracking of dynein. Nature Cell Biology, 2014, 16(8), 804-811. doi: 10.1038/ncb2999
  123. Geertsema, H.J.; Kulczyk, A.W.; Richardson, C.C.; van Oijen, A.M. Single-molecule studies of polymerase dynamics and stoichiometry at the bacteriophage T7 replication machinery. Proceedings of the National Academy of Sciences of the U.S.A., 2014, 111(11), 4073-4078. doi: 10.1073/pnas.1402010111
  124. Graen, T.M.D.; Hoefling, M.; Grubmüller, H. AMBER-DYES: Characterization of Charge Fluctuations and Force Field Parameterization of Fluorescent Dyes for Molecular Dynamics Simulations. Journal of Chemical Theory and Computation, 2014, 10(12), 5505-5512. doi: 10.1021/ct500869p
  125. Hu, X.; Wang, Q.; Liu, Y.; Liu, H.; Qin, C.; Cheng, K.; Robinson, W.; Gray, B.D.; Pak, K.Y.; Yu, A. et al. Optical imaging of articular cartilage degeneration using near-infrared dipicolylamine probes. Biomaterials, 2014, 35(26), 7511-7521. doi: 10.1016/j.biomaterials.2014.05.042
  126. Novo, L.; Rizzo, L.Y.; Golombek, S.K.; Dakwar, G.R.; Lou, B.; Remaut, K.; Mastrobattista, E.; van Nostrum, C.F.; Jahnen-Dechent, W.; Kiessling, F. et al. Decationized polyplexes as stable and safe carrier systems for improved biodistribution in systemic gene therapy. Journal of Controlled Release, 2014, 195, 162-175. doi: 10.1016/j.jconrel.2014.08.028
  127. Zhang, Y.; Ge, C.; Zhu, C.; Salaita, K. DNA-based digital tension probes reveal integrin forces during early cell adhesion. Nature Communications, 2014, 5, 5167-5167. doi: 10.1038/ncomms6167
  128. Chen, H.; Xiao, L.; Anraku, Y.; Mi, P.; Liu, X.; Cabral, H.; Inoue, A.; Nomoto, T.; Kishimura, A.; Nishiyama, N. et al. Polyion Complex Vesicles for Photoinduced Intracellular Delivery of Amphiphilic Photosensitizer. Journal of the American Chemical Society, 2014, 136(1), 157-163. doi: 10.1021/ja406992w
  129. Lee, S.; Ashizawa, A.T.; Kim, K.S.; Falk, D.J.; Notterpek, L. Liposomes to Target Peripheral Neurons and Schwann Cells. PLoS ONE, 2013, 8(11), e78724. doi: 10.1371/journal.pone.0078724
  130. Albertazzi, L.; Martinez-Veracoechea, F.J.; Leenders, C.M.A.; Voets, I.K.; Frenkel, D.; Meijer, E.W. Spatiotemporal control and superselectivity in supramolecular polymers using multivalency. Proceedings of the National Academy of Sciences of the U.S.A., 2013, 110(30), 12203-12208. doi: 10.1073/pnas.1303109110
  131. Cheng, M.-C.; Leske, A.T.; Matsuoka, T.; Kim, B.C.; Lee, J.; Burns, M.A.; Takayama, S.; Biteen, J.S. Super-Resolution Imaging of PDMS Nanochannels by Single-Molecule Micelle-Assisted Blink Microscopy. The Journal of Physical Chemistry B, 2013, 117(16), 4406-4411. doi: 10.1021/jp307635v
  132. Haller, A.; Altman, R.B.; Souliere, M.F.; Blanchard, S.C.; Micura, R. Folding and ligand recognition of the TPP riboswitch aptamer at single-molecule resolution. Proceedings of the National Academy of Sciences of the U.S.A., 2013, 110(11), 4188-4193. doi: 10.1073/pnas.1218062110
  133. He, H.; Chen, S.; Zhou, J.; Dou, Y.; Song, L.; Che, L.; Zhou, X.; Chen, X.; Jia, Y.; Zhang, J. et al. Cyclodextrin-derived pH-responsive nanoparticles for delivery of paclitaxel. Biomaterials, 2013, 34(21), 5344-5358. doi: 10.1016/j.biomaterials.2013.03.068
  134. Rimpelová, S.; Bříza, T.; Králová, J.; Záruba, K.; Kejík, Z.; Císařová, I.; Martásek, P.; Ruml, T.; Král, V. Rational Design of Chemical Ligands for Selective Mitochondrial Targeting. Bioconjugate Chemistry, 2013, 24(9), 1445-1454. doi: 10.1021/bc400291f
  135. Soulière, M.F.; Altman, R.B.; Schwarz, V.; Haller, A.; Blanchard, S.C.; Micura, R. Tuning a riboswitch response through structural extension of a pseudoknot. Proceedings of the National Academy of Sciences of the U.S.A., 2013, 110(35), E3256-E3264. doi: 10.1073/pnas.1304585110
  136. Yang, H.; Mao, H.; Wan, Z.; Zhu, A.; Guo, M.; Li, Y.; Li, X.; Wan, J.; Yang, X.; Shuai, X. et al. Micelles assembled with carbocyanine dyes for theranostic near-infrared fluorescent cancer imaging and photothermal therapy. Biomaterials, 2013, 34(36), 9124-9133. doi: 10.1016/j.biomaterials.2013.08.022
  137. Pecqueur, L.; Duellberg, C.; Dreier, B.; Jiang, Q.; Wang, C.; Pluckthun, A.; Surrey, T.; Gigant, B.; Knossow, M. A designed ankyrin repeat protein selected to bind to tubulin caps the microtubule plus end. Proceedings of the National Academy of Sciences of the U.S.A., 2012, 109(30), 12011-12016. doi: 10.1073/pnas.1204129109
  138. Sparks, J.; Slobodkin, G.; Matar, M.; Congo, R.; Ulkoski, D.; Rea-Ramsey, A.; Pence, C.; Rice, J.; McClure, D.; Polach, K.J. et al. Versatile cationic lipids for siRNA delivery. Journal of Controlled Release, 2012, 158(2), 269-276. doi: 10.1016/j.jconrel.2011.11.006

Cyanine5 алкин

  1. Mietlicki-Baase, E.G.; Liberini, C.G.; Workinger, J.L.; Bonaccorso, R.L.; Borner, T.; Reiner, D.J.; Koch-Laskowski, K.; McGrath, L.E.; Lhamo, R.; Stein, L.M.; De Jonghe, B.C.; Holz, G.G.; Roth, C.L.; Doyle, R.P.; Hayes, M.R. A Vitamin B12 Conjugate of Exendin-4 Improves Glucose Tolerance Without Associated Nausea or Hypophagia in Rodents. Diabetes, Obesity & Metabolism, 2018, 20(5), 1223–1234. doi: 10.1111/dom.13222
  2. Sacoman, J.L.; Dagda, R.Y.; Burnham-Marusich, A.R.; Dagda, R.K.; Berninsone, P.M. Mitochondrial O-GlcNAc transferase (mOGT) regulates mitochondrial structure, function and survival in HeLa cells. Journal of Biological Chemistry, 2017, 292(11), 4499–4518. doi: 10.1074/jbc.M116.726752
  3. Wallat, J.D.; Czapar, A.E.; Wang, C.; Wen, A.M.; Wek, K.S.; Yu, X.; Steinmetz, N.F.; Pokorski, J.K. Optical and Magnetic Resonance Imaging Using Fluorous Colloidal Nanoparticles. Biomacromolecules, 2017, 18(1), 103–112. doi: 10.1021/acs.biomac.6b01389
  4. Zhao, T.; Li, T.; Liu, Y. Silver nanoparticle plasmonic enhanced förster resonance energy transfer (FRET) imaging of protein-specific sialylation on the cell surface. Nanoscale, 2017, 9(28), 9841–9847. doi: 10.1039/c7nr01562c
  5. Ponomarenko, A.I.; Brylev, V.A.; Sapozhnikova, K.A.; Ustinov, A.V.; Prokhorenko, I.A.; Zatsepin, T.S.; Korshun, V.A. Tetrahedral DNA conjugates from pentaerythritol-based polyazides. Tetrahedron, 2016, 72(19), 2386–2391. doi: 10.1016/j.tet.2016.03.051
  6. Burnham-Marusich, A.R.; Plechaty, A.M.; Berninsone, P.M. Size-matched alkyne-conjugated cyanine fluorophores to identify differences in protein glycosylation. Electrophoresis, 2014, 35(18), 2621-2625. doi: 10.1002/elps.201400241
  7. Truong, F.; Yoo, T.H.; Lampo, T.J.; Tirrell, D.A. Two-Strain, Cell-Selective Protein Labeling in Mixed Bacterial Cultures. Journal of the American Chemical Society, 2012, 134(20), 8551-8556. doi: 10.1021/ja3004667

Cyanine5 амин

  1. Wilson, D.R.; Rui, Y.; Siddiq, K.; Routkevitch, D.; Green, J.J. Differentially Branched Ester Amine Quadpolymers with Amphiphilic and pH Sensitive Properties for Efficient Plasmid DNA Delivery. Molecular Pharmaceutics, in press. doi: 10.1021/acs.molpharmaceut.8b00963
  2. van Driessche, A; Kocere, A.; Everaert, H.; Nuhn, L.; van Herck, S.; Griffiths, G.; Fenaroli, F.; de Geest, B.G. pH-sensitive hydrazone-linked doxorubicin nanogels via polymeric activated ester scaffolds: synthesis, assembly, in vitro and in vivo evaluation in tumor bearing zebrafish. Chemistry of Materials, 2018, 30(23), 8587–8596. doi: 10.1021/acs.chemmater.8b03702
  3. Nuhn, L.; De Koker, S.; Van Lint, S.; Zhong, Z.; Catani, J.P.; Combes, F.; Deswarte, K.; Li, Y.; Lambrecht, B.N.; Lienenklaus, S.; Sanders, N.N.; David, S.A.; Tavernier, J.; De Geest, B.G. Nanoparticle-Conjugate TLR7/8 Agonist Localized Immunotherapy Provokes Safe Antitumoral Responses. Advanced Materials, 2018, 30(45), e1803397. doi: 10.1002/adma.201803397
  4. van Herck, S.; Deswarte, K.; Nuhn, L.; Zhong, Z.; Portela Catani, J.P.; Li, Y.; Sanders, N.N.; Lienenklaus, S.; De Koker, S.; Lambrecht, B.N.; David, S.A.; De Geest, B.G. Lymph-Node-Targeted Immune Activation by Engineered Block Copolymer Amphiphiles-TLR7/8 Agonist Conjugates. Journal of the American Chemical Society, 2018, 140, 14300–14307. doi: 10.1021/jacs.8b08595
  5. Babos, G.; Biró, E.; Meiczinger, M.; Feczkó, T. Dual Drug Delivery of Sorafenib and Doxorubicin from PLGA and PEG-PLGA Polymeric Nanoparticles. Polymers, 2018, 10(8), 895. doi: 10.3390/polym10080895
  6. Nuhn, L.; Van Hoecke, L.; Deswarte, K.; Schepens, B.; Li, Y.; Lambrecht, B.N.; De Koker, S.; David, S.A.; Saelens, X.; De Geest, B.G. Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist. Biomaterials, 2018, 178, 643–651. doi: 10.1016/j.biomaterials.2018.03.026
  7. Kongkatigumjorn, N.; Smith, S.A.; Chen, M.Z.; Fang, K.; Yang, S.; Gillies, E.R.; Johnston, A.P.R.; Such, G.K. Controlling Endosomal Escape Using pH Responsive Nanoparticles with Tunable Disassembly. Applied Nano Materials, 2018, 1(7), 3164–3173. doi: 10.1021/acsanm.8b00338
  8. Wang, B.; Chen, G.; Urabe, G.; Xie, R.; Wang, Y.; Shi, X.; Guo, L.-W.; Gong, S.; Kent, K.C. A paradigm of endothelium-protective and stent-free anti-restenotic therapy using biomimetic nanoclusters. Biomaterials, 2018, 178, 293–301. doi: 10.1016/j.biomaterials.2018.06.025
  9. Shih, T.-Y.; Blacklow, S.O.; Li, A.W.; Freedman, B.R.; Bencherif, S.; Koshy, S.T.; Darnell, M.C.; Mooney, D.J. Injectable, Tough Alginate Cryogels as Cancer Vaccines. Advanced Healthcare Materials, 2018, 7(10), 1701469. doi: 10.1002/adhm.201701469
  10. Raghupathi, K.; Skinner, M.; Chang, G.; Crawley, C.; Yoshida-Moriguchi, T.; Pipenhagen, P.; Zhu, Y.; Avila, L.Z.; Miller, R.J.; Dhal, P.K. Hyaluronic Acid Microgels as Intracellular Endosomolysis Reagents. ACS Biomaterials Science & Engineering, 2018, 4(2), 558–565. doi: 10.1021/acsbiomaterials.7b00966
  11. Pan, G.; Jia, T.-t.; Huang, Q.-x. Qiu, Y.-y.; Xu, J. Yin, P.-h.; Liu, T. Mesoporous Silica Nanoparticles (MSNs)-Based Organic/Inorganic Hybrid Nanocarriers Loading 5-Fluorouracil for the Treatment of Colon Cancer with Improved Anticancer Efficacy. Colloids and Surfaces, B: Biointerfaces, 2017, 159, 375–385. doi: 10.1016/j.colsurfb.2017.08.013
  12. Chen, G.; Wang, Y.; Xie, R.; Gong, S. Tumor-targeted pH/redox dual-sensitive unimolecular nanoparticles for efficient siRNA delivery. Journal of Controlled Release, 2017, 259, 105–114. doi: 10.1016/j.jconrel.2017.01.042
  13. Wilson, D.R.; Routkevitch, D.; Rui, Y.; Mosenia, A.; Wahlin, K.J.; Quinones-Hinojosa, A.; Zack, D.J.; Green, J.J. A Triple-Fluorophore Labeled Nucleic Acid pH Nanosensor to Investigate Non-Viral Gene Delivery. Molecular Therapy, 2017, 25(7), 1697–1709. doi: 10.1016/j.ymthe.2017.04.008
  14. Wang, Y.; Wang, L.; Chen, G.; Gong, S. Carboplatin-Complexed and cRGD-Conjugated Unimolecular Nanoparticles for Targeted Ovarian Cancer Therapy. Macromolecular Bioscience, 2017, 17(5), 1600292. doi: 10.1002/mabi.201600292
  15. Qu, J.-B.; Chapman, R.; Chen, F.; Lu, H.; Stenzel, M.H. Swollen Micelles for the Preparation of Gated, Squeezable, pH-Responsive Drug Carriers. ACS Applied Materials & Interfaces, 2017, 9(16), 13865–13874. doi: 10.1021/acsami.7b01120
  16. Yin, M.; Bao, Y.; Gao, X.; Wu, Y.; Sun, Y.; Zhao, X.; Xu, H.; Zhang, Z.; Tan, S. Redox/pH dual-sensitive hybrid micelles for targeting delivery and overcoming multidrug resistance of cancer. Journal of Materials Chemistry B, 2017, 5(16), 2964–2978. doi: 10.1039/c6tb03282f
  17. Glass, J.J.; Li, Y.; De Rose, R.; Johnston, A.P.R.; Czuba, E.I.; Khor, S.Y.; Quinn, J.F.; Whittaker, M.R.; Davis, T.P.; Kent, S.J. Thiol-Reactive Star Polymers Display Enhanced Association with Distinct Human Blood Components. ACS Applied Materials & Interfaces, 2017, 9(14), 12182-12194. doi: 10.1021/acsami.6b15942
  18. Zhang, R.; Yang, J.; Radford, D.C.; Fang, Y.; Kopeček, J. FRET Imaging of Enzyme-Responsive HPMA Copolymer Conjugate. Macromolecular Bioscience, 2017, 17(1), 1600125. doi: 10.1002/mabi.201600125
  19. Shalgunov, V.; Zaytseva-Zotova, D.; Zinchenko, A.; Levada, T.; Shilov, Y.; Andreyev, D.; Dzhumashev, D.; Metelkin, E.; Urusova, A.; Demin, O.; McDonnell, K.; Troiano, G.; Zale, S.; Safarovа, E. Comprehensive study of the drug delivery properties of poly(L-lactide)-poly(ethylene glycol) nanoparticles in rats and tumor-bearing mice. Journal of Controlled Release, 2017, 261, 31–42. doi: 10.1016/j.jconrel.2017.06.006
  20. Stefanello, T.; Couturaud, B.; Szarpak, A.; Fournier, D.; Louage, B.; Garcia, F.; Vataru Nakamura, C.; De Geest, B.; Woisel, P.; van der Sanden, B.; Auzely, R. Coumarin-containing thermoresponsive hyaluronic acid-based nanogels as delivery systems for anticancer chemotherapy. Nanoscale, 2017, 9(33), 12150–12162. doi: 10.1039/C7NR03964F
  21. Yang, W.; Xia, Y.; Zou, Y.; Meng, F.; Zhang, J.; Zhong, Z. Bioresponsive Chimaeric Nano-polymersomes Enable Targeted and Efficacious Protein Therapy for Human Lung Cancers in Vivo. Chemistry of Materials, 2017, 29(20), 8757–8765. doi: 10.1021/acs.chemmater.7b02953
  22. Pombo-García, K.; Weiss, S.; Zarschler, K.; Ang, C.-S.; Hübner, R.; Pufe, J.; Meister, S.; Seidel, J.; Pietzsch, J.; Spiccia, L.; Stephan, H.; Graham, B. Zwitterionic polymer-coated ultrasmall superparamagnetic iron oxide nanoparticles with low protein interaction and high biocompatibility. ChemNanoMat, 2016, 2(10), 959–971. doi: 10.1002/cnma.201600233
  23. Mann, S.K.; Dufour, A.; Glass, J.J.; De Rose, R.; Kent, S.J.; Such, G.K.; Johnston, A.P.R. Tuning the properties of pH responsive nanoparticles to control cellular interactions in vitro and ex vivo. Polymer Chemistry, 2016, 7(38), 6015–6024. doi: 10.1039/c6py01332e
  24. Mann, S.K.; Czuba, E.; Selby, L.I.; Such, G.K.; Johnston, A.P.R. Quantifying Nanoparticle Internalization Using a High Throughput Internalization Assay. Pharmaceutical Research, 2016, 33(10), 2421–2432. doi: 10.1007/s11095-016-1984-3
  25. Priwitaningrum, D.L.; Blonde, J.-B.; van Baarlen, J.; Hennink, W.E.; Storm, G.; Le Gac, S.; Prakash, J. Tumor stroma-containing 3D spheroid arrays: A tool to study nanoparticle penetration. Journal of Controlled Release, 2016, 244(Part B), 257–268. doi: 10.1016/j.jconrel.2016.09.004
  26. Zhu, Y.; Wang, X.; Chen, J.; Zhang, J.; Meng, F.; Deng, C.; Cheng, R.; Feijen, J.; Zhong, Z. Bioresponsive and fluorescent hyaluronic acid-iodixanol nanogels for targeted X-ray computed tomography imaging and chemotherapy of breast tumors. Journal of controlled release, 2016, 244(Part B), 229–239. doi: 10.1016/j.jconrel.2016.08.027
  27. Hartley, J.M.; Zhang, R.; Gudheti, M.; Yang, J.; Kopeček, J. Tracking and quantifying polymer therapeutic distribution on a cellular level using 3D dSTORM. Journal of Controlled Release, 2016, 231, 50–59. doi: 10.1016/j.jconrel.2016.02.005
  28. Bruckman, M.A.; Czapar, A.E.; VanMeter, A.; Randolph, L.N.; Steinmetz, N.F. Tobacco mosaic virus-based protein nanoparticles and nanorods for chemotherapy delivery targeting breast cancer. Journal of Controlled Release, 2016, 231, 103–113. doi: 10.1016/j.jconrel.2016.02.045
  29. Liu, T.; Yuan, X.; Jia, T.; and Liu, C.; Ni, Z.; Qin, Z.; Yuan, Y. Polymeric Prodrug of Bufalin for Increasing Solubility and Stability: Synthesis and Anticancer Study in Vitro and in Vivo. International Journal of Pharmaceutics, 2016, 506(1–2), 382–393. doi: 10.1016/j.ijpharm.2016.04.041
  30. Pan, G.; Bao, Y.-J.; Xu, J.; Liu, T.; Liu, C.; Qiu, Y.-Y.; Shi, X.-J.; Yu, H.; Jia, T.-T.; Yuan, X.; Yuan, Z.-T.; Yin, P.-H.; Cao, Y.-J. Esterase-responsive polymeric prodrug-based tumor targeting nanoparticles for improved anti-tumor performance against colon cancer. RSC Advances, 2016, 6(48), 42109–42119. doi: 10.1039/c6ra05236c
  31. Gao, D.; Zhang, P.; Liu, C.; Chen, C.; Gao, G.; Wu, Y.; Sheng, Z.; Song, L.; Cai, L. Compact chelator-free Ni-integrated CuS nanoparticles with tunable near-infrared absorption and enhanced relaxivity for in vivo dual-modal photoacoustic/MR imaging. Nanoscale, 2015, 7, 17631–17636. doi: 10.1039/C5NR05237H
  32. Yang, J.; Zhang, R.; Radford, D.C.; Kopeček, J. FRET-trackable biodegradable HPMA copolymer-epirubicin conjugates for ovarian carcinoma therapy. Journal of Controlled Release, 2015, 218, 36–44. doi: 10.1016/j.jconrel.2015.09.045
  33. Fuchs, A.V.; Tse, B.W.C.; Pearce, A.K.; Yeh, M.-C.; Fletcher, N.L.; Huang, S.S.; Heston, W.D.; Whittaker, A.K.; Russell, P.J.; Thurecht, K.J. Evaluation of Polymeric Nanomedicines Targeted to PSMA: Effect of Ligand on Targeting Efficiency. Biomacromolecules, 2015, 16(10), 3235–3247. doi: 10.1021/acs.biomac.5b00913
  34. Li, H.; Yang, Z.-Y.; Liu, C.; Zeng, Y.-P.; Hao, Y.-H. Gu, Y.; Wang, W.-D.; Li, R. PEGylated ceria nanoparticles used for radioprotection on Human liver cells under γ-ray irradiation. Free Radical Biology and Medicine, 2015, 87, 26–35. doi: 10.1016/j.freeradbiomed.2015.06.010
  35. Guo, Y.; Wang, D.; Song, Q.; Wu, T.; Zhuang, X.; Bao, Y.; Kong, M.; Qi, Y.; Tan, S.; Zhang, Z. Erythrocyte Membrane-Enveloped Polymeric Nanoparticles as Nanovaccine for Induction of Antitumor Immunity against Melanoma. ACS Nano, 2015, 9(7), 6918–6933. doi: 10.1021/acsnano.5b01042
  36. Ma, Y.; Fuchs, A.; Boase, N.R.B.; Rolfe, B.E.; Coombes, A.G.A.; Thurecht, K.J. The in vivo fate of nanoparticles and nanoparticle-loaded microcapsules after oral administration in mice: evaluation of their potential for colon-specific delivery. European Journal of Pharmaceutics and Biopharmaceutics, 2015, 94, 393–403. doi: 10.1016/j.ejpb.2015.06.014
  37. Zhang, R.; Yang, J.; Sima, M.; Zhou, Y.; Kopeček, J. Sequential combination therapy of ovarian cancer with degradable N-(2-hydroxypropyl)methacrylamide copolymer paclitaxel and gemcitabine conjugates. Proceedings of the National Academy of Sciences of the U.S.A., 2014, 111(33), 12181-12186. doi: 10.1073/pnas.1406233111

Cyanine5 гидразид

  1. Boone, C.; Grove, R.; Adamcova, D.; Braga, C.; Adamec, J. Revealing oxidative damage to enzymes of carbohydrate metabolism in yeast: An integration of 2D DIGE, quantitative proteomics and bioinformatics. Proteomics, 2016, 16(13), 1889–1903. doi: 10.1002/pmic.201500546
  2. Yoshimura, T.; Harashima, M.; Kurogi, K.; Suiko, M.; Liu, M.-C.; Sakakibara, Y. A novel procedure for the assessment of the antioxidant capacity of food components. Analytical Biochemistry, 2016, 507, 7–12. doi: 10.1016/j.ab.2016.05.002
  3. Huang, J.; Smith, F.; Panizzi, J.R.; Goodwin, D.C.; Panizzi, P. Inactivation of myeloperoxidase by benzoic acid hydrazide. Archives of Biochemistry and Biophysics, 2015, 570, 14–22. doi: 10.1016/j.abb.2015.01.028
  4. Einfalt, T.; Goers, R.; Dinu, I.A.; Najer, A.; Spulber, M.; Onaca-Fischer, O.; Palivan, C.G. Stimuli-triggered activity of nanoreactors by biomimetic engineering polymer membranes. Nano Letters, 2015, 15(11), 7596–7603. doi: 10.1021/acs.nanolett.5b03386
  5. Nienhaus, L.; Gross, D.E.; Xue, Z.; Moore, J.S.; Gruebele, M. Intramolecular energy transfer in a synthetic dendron-based light harvesting system. Journal of Photochemistry and Photobiology A: Chemistry, 2014, 295, 26-33. doi: 10.1016/j.jphotochem.2014.08.014
  6. Xie, M.; Xu, Y.; Shen, H.; Shen, S.; Ge, Y.; Xie, J. Negative-charge-functionalized mesoporous silica nanoparticles as drug vehicles targeting hepatocellular carcinoma. International Journal of Pharmaceutics, 2014, 474, 223-231. doi: 10.1016/j.ijpharm.2014.08.027
  7. Chang, Y.; Cai, C.; Li, L.; Miao, J.; Ucakturk, E.; Li, G.; Ly, M.; Linhardt, R.J. Ultrasensitive Detection and Quantification of Acidic Disaccharides Using Capillary Electrophoresis and Quantum Dot-Based Fluorescence Resonance Energy Transfer. Analytical Chemistry, 2013, 85(19), 9356-9362. doi: 10.1021/ac402242v
  8. Shen, H.; Shi, H.; Xie, M.; Ma, K.; Li, B.; Shen, S.; Wang, X.; Jin, Y. Biodegradable chitosan/alginate BSA-gel-capsules for pH-controlled loading and release of doxorubicin and treatment of pulmonary melanoma. Journal of Materials Chemistry B, 2013, 1(32), 3906-3906. doi: 10.1039/c3tb20330a
  9. Xie, M.; Shi, H.; Li, Z.; Shen, H.; Ma, K.; Li, B.; Shen, S.; Jin, Y. A multifunctional mesoporous silica nanocomposite for targeted delivery, controlled release of doxorubicin and bioimaging. Colloids and Surfaces B: Biointerfaces, 2013, 110, 138-147. doi: 10.1016/j.colsurfb.2013.04.009
  10. Xie, M.; Shi, H.; Ma, K.; Shen, H.; Li, B.; Shen, S.; Wang, X.; Jin, Y. Hybrid nanoparticles for drug delivery and bioimaging: Mesoporous silica nanoparticles functionalized with carboxyl groups and a near-infrared fluorescent dye. Journal of Colloid and Interface Science, 2013, 395, 306-314. doi: 10.1016/j.jcis.2013.01.001
  11. Xie, M.; Shi, H.; Ma, K.; Shen, H.; Li, B.; Shen, S.; Wang, X.; Jin, Y. Hybrid nanoparticles for drug delivery and bioimaging: Mesoporous silica nanoparticles functionalized with carboxyl groups and a near-infrared fluorescent dye. Journal of Colloid and Interface Science, 2013, 395, 306-314. doi: 10.1016/j.jcis.2013.01.001

Cyanine5 для разностного электрофореза

  1. Laberge, A.; Ayoub, A.; Arif, S.; Larochelle, S.; Garnier, A.; Moulin, V.J. α-2-Macroglobulin induces the shedding of microvesicles from cutaneous wound myofibroblasts. Journal of Cellular Physiology, in press. doi: 10.1002/jcp.27794
  2. Malheiros, J.M.; Braga, C.P.; Grove, R.A.; Ribeiro, F.A.; Calkins, C.R.; Adamec, J.; Chardulo, L.A.L. Influence of oxidative damage to proteins on meat tenderness using a proteomics approach. Meat Science, 2019, 148, 64–71. doi: 10.1016/j.meatsci.2018.08.016
  3. Jin, Y.N.; Schlueter, P.J.; Jurisch-Yaksi, N.; Lam, P.-Y.; Jin, S.; Hwang, W.Y.; Yeh, J.-R.J.; Yoshigi, M.; Ong, S.-E.; Schenone, M.; Hartigan, C.R.; Carr, S.A.; Peterson, R.T. Noncanonical translation via deadenylated 3' UTRs maintains primordial germ cells. Nature Chemical Biology, 2018, 14(9), 844–852. doi: 10.1038/s41589-018-0098-0
  4. Lu, J.; Tang, M.; Liu, Y.; Wang, J.; Wu, Z. Comparative Proteomics of Chromium-Transformed Beas-2B Cells by 2D-DIGE and MALDI-TOF/TOF MS. Biological Trace Element Research, 2018, 185(1), 78–88. doi: 10.1007/s12011-017-1222-9
  5. Tamošiūnė, I.; Stanienė, G.; Haimi, P.; Stanys, V.; Rugienius, R.; Baniulis, D. Endophytic Bacillus and Pseudomonas spp. Modulate Apple Shoot Growth, Cellular Redox Balance, and Protein Expression Under in Vitro Conditions. Frontiers in Plant Science, 2018, 9, 889. doi: 10.3389/fpls.2018.00889
  6. Tsikandelova, R.; Mladenov, P.; Planchon, S.; Kalenderova, S.; Praskova, M.; Mihaylova, Z.; Stanimirov, P.; Mitev, V.; Renaut, J.; Ishkitiev, N. Proteome response of dental pulp cells to exogenous FGF8. Journal of Proteomics, 2018, 183, 14–24. doi: 10.1016/j.jprot.2018.05.004
  7. Jun, D.; Minic, Z.; Bhat, S.V.; Vanderlinde, E.M.; Yost, C.K.; Babu, M.; Dahms, T.E.S. Metabolic Adaptation of a C-Terminal Protease A-Deficient Rhizobium leguminosarum in Response to Loss of Nutrient Transport. Frontiers in Microbiology, 2018, 8, 2617. doi: 10.3389/fmicb.2017.02617
  8. Shields, K.J.; Wu, C. Differential Adipose Tissue Proteomics. Methods in Molecular Biology, 2017, 1788, 243–250. doi: 10.1007/7651_2017_80
  9. Zhao, P.; George, J.V.; Li, B.; Amini, N.; Paluh, J.; Wang, J. Clickable Multifunctional Dumbbell Particles for In Situ Multiplex Single-Cell Cytokine Detection. ACS Applied Materials & Interfaces, 2017, 9(38), 32482–32488. doi: 10.1021/acsami.7b08338
  10. Haimi, P.; Vinskiene, J.; Stepulaitiene, I.; Baniulis, D.; Stanienė, G.; Šikšnianienė, J.B.; Rugienius, R. Patterns of low temperature-Induced accumulation of dehydrins in Rosaceae crops — Evidence for post-translational modification in apple. Journal of Plant Physiology, 2017, 218, 175–181. doi: 10.1016/j.jplph.2017.08.008
  11. Merjaneh, M.; Langlois, A.; Larochelle, S.; Cloutier, C.B.; Ricard-Blum, S.; Moulin, V.J. Pro-angiogenic capacities of microvesicles produced by skin wound myofibroblasts. Angiogenesis, 2017, 20(3), 385–398. doi: 10.1007/s10456-017-9554-9
  12. Sikorskaite-Gudziuniene, S.; Haimi, P.; Gelvonauskiene, D.; Stanys, V. Nuclear proteome analysis of apple cultivar ‘Antonovka’ accessions in response to apple scab (Venturia inaequalis). European Journal of Plant Pathology, 2017, 148(4), 771–784. doi: 10.1007/s10658-016-1131-3
  13. Heller, D.; Helmerhorst, E.J.; Oppenheim, F.G. Saliva and Serum Protein Exchange at the Tooth Enamel Surface. Journal of Dental Research, 2017, 96(4), 437–443. doi: 10.1177/0022034516680771
  14. Bian, Y.; Deng, X.; Yan, X.; Zhou, J.; Yuan, L.; Yan, Y. Integrated proteomic analysis of Brachypodium distachyon roots and leaves reveals a synergistic network in the response to drought stress and recovery. Scientific Reports, 2017, 7, 46183. doi: 10.1038/srep46183
  15. Kaux JF, Libertiaux V, Leprince P, Fillet M, Denoel V Wyss C, Lecut C, Gothot A, Le Goff C, Croisier JL, Crielaard JM, Drion P. Eccentric Training for Tendon Healing After Acute Lesion: A Rat Model. The American Journal of Sports Medicine, 2017, 45(6), 1440–1446. doi: 10.1177/0363546517689872
  16. Nemethova, M.; Talian, I.; Danielisova, V.; Tkacikova, S.; Bonova, P.; Bober, P.; Matiasova, M.; Sabo, J.; Burda, J. Delayed bradykinin postconditioning modulates intrinsic neuroprotective enzyme expression in the rat CA1 region after cerebral ischemia: a proteomic study. Metabolic Brain Disease, 2016, 31(6), 1391–1403. doi: 10.1007/s11011-016-9859-1
  17. Boone, C.; Grove, R.; Adamcova, D.; Braga, C.; Adamec, J. Revealing oxidative damage to enzymes of carbohydrate metabolism in yeast: An integration of 2D DIGE, quantitative proteomics and bioinformatics. Proteomics, 2016, 16(13), 1889–1903. doi: 10.1002/pmic.201500546
  18. Bertrand, A.; Bipfubusa, M.; Castonguay, Y.; Rocher, S.; Szopinska-Morawska, A.; Papadopoulos, Y.; Renaut, J. A proteome analysis of freezing tolerance in red clover (Trifolium pratense L.). BMC Plant Biology, 2016, 16, 65. doi: 10.1186/s12870-016-0751-2
  19. Bipfubusa, M.; Rocher, S.; Bertrand, A.; Castonguay, Y.; Renaut, J. Dataset of protein changes induced by cold acclimation in red clover (Trifolium pratense L.) populations recurrently selected for improved freezing tolerance. Data in Brief, 2016, 8, 570–574. doi: 10.1016/j.dib.2016.06.003
  20. Wang, Z.; Zourelias, L.; Wu, C.; Edwards, P.C.; Trombetta, M.; Passineau, M.J. Ultrasound-assisted nonviral gene transfer of AQP1 to the irradiated minipig parotid gland restores fluid secretion. Gene Therapy, 2015, 22, 739–749. doi: 10.1038/gt.2015.36
  21. Lu, J.; Zhou, Z.; Zheng, J.; Zhang, Z.; Lu, R.; Liu, H.; Shi, H.; Tu, Z. 2D-DIGE and MALDI TOF/TOF MS analysis reveal that small GTPase signaling pathways may play an important role in cadmium-induced colon cell malignant transformation. Toxicology and Applied Pharmacology, 2015, 288(1), 106–113. doi: 10.1016/j.taap.2015.07.020
  22. Printz, B.; Guerriero, G.; Sergeant, K.; Renaut, J.; Lutts, S.; Hausman, J.-F. Ups and downs in alfalfa: Proteomic and metabolic changes occurring in the growing stem. Plant Science, 2015, 238, 13–25. doi: 10.1016/j.plantsci.2015.05.014
  23. Ashoub, A.; Baeumlisberger, M.;Neupaertl, M.; Karas, M.; Brüggemann, W. Characterization of common and distinctive adjustments of wild barley leaf proteome under drought acclimation, heat stress and their combination. Plant Molecular Biology, 2015, 87(4–5), 459–471. doi: 10.1007/s11103-015-0291-4
  24. Feret, R.; Lilley, K.S. Protein Profiling Using Two-Dimensional Difference Gel Electrophoresis (2-D DIGE). Current Protocols in Protein Science, 2014, 22.2.1-22.2.17. doi: 10.1002/0471140864.ps2202s75
  25. Molinari, C.E.; Casadio, Y.S.; Hartmann, B.T.; Livk, A.; Bringans, S.; Arthur, P.G.; Hartmann, P.E. Proteome Mapping of Human Skim Milk Proteins in Term and Preterm Milk. Journal of Proteome Research, 2012, 11(3), 1696-1714. doi: 10.1021/pr2008797

Cyanine5 карбоновая кислота

  1. Santra, K.; Clark, K.D.; Maity, N.; Petrich, J.W.; Anderson, J.L. Exploiting Fluorescence Spectroscopy to Identify Magnetic Ionic Liquids Suitable for the Isolation of Oligonucleotides. The Journal of Physical Chemistry B, 2018, 122(31), 7747–7756. doi: 10.1021/acs.jpcb.8b05580
  2. Semkina, A.S.; Abakumov, M.A.; Skorikov, A.S.; Abakumova, T.O.; Melnikov, P.A.; Grinenko, N.F.; Cherepanov, S.A.; Vishnevskiy, D.A.; Naumenko, V.A.; Ionova, K.P.; Majouga, A.G.; Chekhonin, V.P. Multimodal doxorubicin loaded magnetic nanoparticles for {VEGF} targeted theranostics of breast cancer. Nanomedicine: Nanotechnology, Biology and Medicine, 2018, 14(5), 1733–1742. doi: 10.1016/j.nano.2018.04.019
  3. Kwok, S.J.J.; Choi, M.; Bhayana, B.; Zhang, X.; Ran, C.; Yun, S.-H. Two-photon excited photoconversion of cyanine-based dyes. Scientific Reports, 2016, 6, 23866. doi: 10.1038/srep23866
  4. Gupta, A.; Verma, N.C.; Khan, S.; Tiwari, S.; Chaudhary, A.; Nandi, C.K. Paper strip based and live cell ultrasensitive lead sensor using carbon dots synthesized from biological media. Sensors and Actuators B: Chemical, 2016, 232, 107–114. doi: 10.1016/j.snb.2016.03.110
  5. Deyle, K.M.; Farrow, B.; Hee, Y.Q.; Work, J.; Wong, M.; Lai, B.; Umeda, A.; Millward, S.W.; Nag, A.; Das, S.; Heath, J.R. A protein-targeting strategy used to develop a selective inhibitor of the E17K point mutation in the PH domain of Akt1. Nature Chemistry, 2015, 7, 455–462. doi: 10.1038/nchem.2223
  6. Rand, M.D.; Montgomery, S.L.; Prince, L.; Vorojeikina, D. Developmental Toxicity Assays Using the Drosophila Model. Current Protocols in Toxicology, 2014, 1.12.1-1.12.20. doi: 10.1002/0471140856.tx0112s59

Cyanine5 малеимид

  1. Gagni, P.; Romanato, A.; Bergamaschi, G.; Bettotti, P.; Vanna, R.; Piotto, C.; Morasso, C.F.; Chiari, M.; Cretich, M.; Gori, A. A self-assembling peptide hydrogel for ultrarapid 3D bioassays. Nanoscale Advances, in press. doi: 10.1039/c8na00158h
  2. Wu, B.; Zhang, H.; Sun, R.; Peng, S.; Cooperman, B.S.; Goldman, Y.E.; Chen, C. Translocation kinetics and structural dynamics of ribosomes are modulated by the conformational plasticity of downstream pseudoknots. Nucleic Acids Research, 2018, 46(18), 9736–9748. doi: 10.1093/nar/gky636
  3. Khor, S.Y.; Vu, M.N.; Pilkington, E.H.; Johnston, A.P.R.; Whittaker, M.R.; Quinn, J.F.; Truong, N.P.; Davis, T.P. Elucidating the Influences of Size, Surface Chemistry, and Dynamic Flow on Cellular Association of Nanoparticles Made by Polymerization-Induced Self-Assembly. Small, 2018, 14(34), e1801702. doi: 10.1002/smll.201801702
  4. Chambre, L.; Degirmenci, A.; Sanyal, R.; Sanyal, A. Multifunctional Nanogels as Theranostic Platforms: Exploiting Reversible and Non-reversible Linkages for Targeting, Imaging and Drug Delivery. Bioconjugate Chemistry, 2018, 29(6), 1885–1896. doi: 10.1021/acs.bioconjchem.8b00085
  5. Robinson, K.J.; Huynh, G.T.; Kouskousis, B.; Fletcher, N.L.; Houston, Z.H.; Thurecht, K.J.; Corrie, S.R. Modified organosilica core-shell nanoparticles for stable pH sensing in biological solutions. ACS Sensors, 2018, 3(5), 967–975. doi: 10.1021/acssensors.8b00034
  6. Gadkari, V.V.; Harvey, S.R.; Raper, A.T.; Chu, W.-T.; Wang, J.; Wysocki, V.H.; Suo, Z. Investigation of sliding DNA clamp dynamics by single-molecule fluorescence, mass spectrometry and structure-based modeling. Nucleic Acids Research, 2018, 46(6), 3103–3118. doi: 10.1093/nar/gky125
  7. Raper, A.T.; Stephenson, A.A.; Suo, Z. Functional Insights Revealed by the Kinetic Mechanism of CRISPR/Cas9. Journal of the American Chemical Society, 2018, 140(8), 2971–2984. doi: 10.1021/jacs.7b13047
  8. Jani, S.; Jackson, A.; Davies-Sala, C.; Chiem, K.; Soler-Bistué, A.; Zorreguieta, A.; Tolmasky, M.E. Assessment of External Guide Sequences' (EGS) Efficiency as Inducers of RNase P-Mediated Cleavage of mRNA Target Molecules. Methods in Molecular Biology, 2018, 1737, 89–98. doi: 10.1007/978-1-4939-7634-8_6
  9. Condon, S.G.F.; Mahbuba, D.-A.; Armstrong, C.R.; Díaz-Vázquez, G.; Craven, S.J.; LaPointe, L.M.; Khadria, A.S.; Chadda, R.; Crooks, J.A.; Rangarajan, N.; Weibel, D.B.; Hoskins, A.A.; Robertson, J.L.; Cui, Q.; Senes, A. The FtsLB sub-complex of the bacterial divisome is tetramer with an uninterrupted FtsL helix linking the transmembrane and periplasmic regions. Journal of Biological Chemistry, 2018, 293(5), 1623–1641. doi: 10.1074/jbc.RA117.000426
  10. Deyaert, E.; Wauters, L.; Guaitoli, G.; Konijnenberg, A.; Leemans, M.; Terheyden, S.; Petrovic, A.; Gallardo, R.; Nederveen-Schippers, L.M.; Athanasopoulos, P.S.; Pots, H.; Van Haastert, P.J.M.; Sobott, F.; Gloeckner, C.J.; Efremov, R.; Kortholt, A.; Versées, W. A homologue of the Parkinson's disease-associated protein LRRK2 undergoes a monomer-dimer transition during GTP turnover. Nature Communications, 2017, 8(1), 1008. doi: 10.1038/s41467-017-01103-4
  11. Baranova, N.; Loose, M. Single-molecule measurements to study polymerization dynamics of FtsZ-FtsA copolymers. Methods in Cell Biology, 2017, 137, 355–370. doi: 10.1016/bs.mcb.2016.03.036
  12. Zhang, Z.; Yomo, D.; Gradinaru, C. Choosing the right fluorophore for single-molecule fluorescence studies in a lipid environment. Biochimica et Biophysica Acta – Biomembranes, 2017, 1859(7), 1242–1253. doi: 10.1016/j.bbamem.2017.04.001
  13. Chen, L.; Weinmeister, R.; Kralovicova, J.; Eperon, L.P.; Vorechovsky, I.; Hudson, A.J.; Eperon, I.C. Stoichiometries of U2AF35, U2AF65 and snRNP reveal new early spliceosome assembly pathways. Nucleic Acids Research, 2017, 45(4), 2051–2067. doi: 10.1093/nar/gkw860
  14. Hinde, E.; Thammasiraphop, K.; Duong, H.T.T.; Yeow, J.; Karagoz, B.; Boyer, C.; Gooding, J.J.; Gaus, K. Pair correlation microscopy reveals the role of nanoparticle shape in intracellular transport and site of drug release. Nature Nanotechnology, 2017, 12(1), 81–89. doi: 10.1038/nnano.2016.160
  15. Sahle, F.F.; Giulbudagian, M.; Bergueiro, J.; Lademann, J.; Calderón, M. Dendritic polyglycerol and N-isopropylacrylamide based thermoresponsive nanogels as smart carriers for controlled delivery of drugs through the hair follicle. Nanoscale, 2017, 9(1), 172–182. doi: 10.1039/c6nr06435c
  16. Qiu, Y.; Levendosky, R.F.; Chakravarthy, S.; Patel, A.; Bowman, G.D.; Myong, S. The Chd1 Chromatin Remodeler Shifts Nucleosomal DNA Bidirectionally as a Monomer. Molecular Cell, 2017, 68(1), 76–88.e6. doi: 10.1016/j.molcel.2017.08.018
  17. Jackson, A.; Jani, S.; Sala, C.D.; Soler-Bistué, A.J.C.; Zorreguieta, A.; Tolmasky, M.E. Assessment of configurations and chemistries of bridged nucleic acids-containing oligomers as external guide sequences: a methodology for inhibition of expression of antibiotic resistance genes. Biology Methods and Protocols, 2016, 1(1), bpw001. doi: 10.1093/biomethods/bpw001
  18. Yoshimura, T.; Kurogi, K.; Liu, M.-C.; Suiko, M.; Sakakibara, Y. A proteomic approach for the analysis of S-nitrosylated proteins using a fluorescence labeling technique. Journal of Electrophoresis, 2016, 60(1), 5–14. doi: 10.2198/jelectroph.60.5
  19. Xue, C.; Whitis, N.R.; Sashital, D.G. Conformational Control of Cascade Interference and Priming Activities in CRISPR Immunity. Molecular Cell, 2016, 64(4), 826–834. doi: 10.1016/j.molcel.2016.09.033
  20. Kollarigowda, R.H.; De Santo, I.; Rianna, C.; Fedele, C.; Manikas, A.C.; Cavalli, S.; Netti, P.A. Shedding light on azopolymer brush dynamics by fluorescence correlation spectroscopy. Soft Matter, 2016, 12(34), 7102–7111. doi: 10.1039/c6sm01482h
  21. Chadda, R.; Krishnamani, V.; Mersch, K.; Wong, J.; Brimberry, M.; Chadda, A.; Kolmakova-Partensky, L.; Friedman, L.J.; Gelles, J.; Robertson, J.L. The dimerization equilibrium of a ClC Cl/H+ antiporter in lipid bilayers. eLIFE, 2016, 5, e17438. doi: 10.7554/eLife.17438
  22. Zhao, Y.; Wei, Z.; Zhao, H.; Jia, J.; Chen, Z.; Zhang, S.; Ouyang, Z.; Ma, X.; Zhang, X. In situ Ion-Transmission Mass Spectrometry for Paper-Based Analytical Devices. Analytical Chemistry, 2016, 88(22), 10805–10810. doi: 10.1021/acs.analchem.6b03272
  23. Noriega, R.; Finley, D.T.; Haberstroh, J.; Geissler, P.L.; Francis, M.B.; Ginsberg, N.S. Manipulating Excited-State Dynamics of Individual Light-Harvesting Chromophores through Restricted Motions in a Hydrated Nanoscale Protein Cavity. The Journal of Physical Chemistry B, 2015, 119(23), 6963–6973. doi: 10.1021/acs.jpcb.5b03784
  24. Leonard, J.D.; Narlikar, G.J. A Nucleotide-Driven Switch Regulates Flanking DNA Length Sensing by a Dimeric Chromatin Remodeler. Molecular Cell, 2015, 57(5), 850–859. doi: 10.1016/j.molcel.2015.01.008
  25. Popp, M.W. Site-Specific Labeling of Proteins via Sortase: Protocols for the Molecular Biologist. Methods in Molecular Biology, 2015, 1266, 185–198. doi: 10.1007/978-1-4939-2272-7_13
  26. Lipchik, A.M.; Perez, M.; Cui, W.; Parker, L.L. Multicolored, Tb3+-Based Antibody-Free Detection of Multiple Tyrosine Kinase Activities. Analytical Chemistry, 2015, 87(15), 7555–7558. doi: 10.1021/acs.analchem.5b02233
  27. Graen, T.M.D.; Hoefling, M.; Grubmüller, H. AMBER-DYES: Characterization of Charge Fluctuations and Force Field Parameterization of Fluorescent Dyes for Molecular Dynamics Simulations. Journal of Chemical Theory and Computation, 2014, 10(12), 5505-5512. doi: 10.1021/ct500869p
  28. Damayanti, N.P.; Parker, L.L.; Irudayaraj, J.M.K. Fluorescence Lifetime Imaging of Biosensor Peptide Phosphorylation in Single Live Cells. Angewandte Chemie International Edition, 2013, 52(14), 3931-3934. doi: 10.1002/anie.201209303
  29. Hartley, M.D.; Schneggenburger, P.E.; Imperiali, B. Lipid bilayer nanodisc platform for investigating polyprenol-dependent enzyme interactions and activities. Proceedings of the National Academy of Sciences of the U.S.A., 2013, 110(52), 20863-20870. doi: 10.1073/pnas.1320852110

Cyanine5.5 азид

  1. Sun, H.; Yan, L.; Carter, K.A.; Zhang, J.; Caserto, J.; Lovell, J.F.; Wu, Y.; Cheng, C. Zwitterionic Crosslinked Biodegradable Nanocapsules for Cancer Imaging. Langmuir, in press. doi: 10.1021/acs.langmuir.8b01633
  2. Stefaniak, J.; Lewis, A.M.; Conole, D.; Galan, S.R.G.; Bataille, C.J.R.; Wynne, G.M.; Castaldi, M.P.; Lundbäck, T.; Russell, A.J.; Huber, K.V.M. Chemical Instability and Promiscuity of Arylmethylidenepyrazolinone-Based MDMX Inhibitors. ACS Chemical Biology, 2018, 13(10), 2849–2854. doi: 10.1021/acschembio.8b00665
  3. Tian, T.; Zhang, H.-X.; He, C.-P.; Fan, S.; Zhu, Y.-L.; Qi, C.; Huang, N.-P.; Xiao, Z.-D.; Lu, Z.-H.; Tannous, B.A.; Gao, J. Surface functionalized exosomes as targeted drug delivery vehicles for cerebral ischemia therapy. Biomaterials, 2018, 150, 137–149. doi: 10.1016/j.biomaterials.2017.10.012
  4. Cho, C.-F.; Wolfe, J.M.; Fadzen, C.M.; Calligaris, D.; Hornburg, K.; Chiocca, E.A.; Agar, N.Y.R.; Pentelute, B.L.; Lawler, S.E. Blood-brain-barrier spheroids as an in vitro screening platform for brain-penetrating agents. Nature Communications, 2017, 8, 15623. doi: 10.1038/ncomms15623
  5. Li, N.; Cai, H.; Jiang, L.; Hu, J.; Bains, A.; Hu, J.; Gong, Q.; Luo, K.; Gu, Z. Enzyme-Sensitive and Amphiphilic PEGylated Dendrimer-Paclitaxel Prodrug Based Nanoparticles for Enhanced Stability and Anticancer Efficacy. ACS Applied Materials & Interfaces, 2017, 9(8), 6865–6877. doi: 10.1021/acsami.6b15505
  6. Garg, S.M.; Paiva, I.M.; Vakili, M.R.; Soudy, R.; Agopsowicz, K.; Soleimani, A.; Hitt, M.; Kaur, K.; Lavasanifar, A. Traceable PEO-poly(ester) micelles for breast cancer targeting: The effect of core structure and targeting peptide on micellar tumor accumulation. Biomaterials, 2017, 144, 17–29. doi: 10.1016/j.biomaterials.2017.08.001
  7. Sun, Y.; Hong, S.; Ma, X.; Cheng, K.; Wang, J.; Zhang, Z.; Yang, M.; Jiang, Y.; Hong, X.; Cheng, Z. Recyclable Cu(I)/Melanin Dots for Cycloadditions, Bioconjugation and Cell Labeling. Chemical Science, 2016, 7(9), 5888–5892. doi: 10.1039/c6sc01536k
  8. Huang, R.; Conti, P.S.; Chen, K. In Vivo Tumor Angiogenesis Imaging Using Peptide-Based Near-Infrared Fluorescent Probes. Methods in Molecular Biology, 2016, 1444, 73–84. doi: 10.1007/978-1-4939-3721-9_8
  9. Puthenveetil, S.; Musto, S.; Loganzo, F.; Tumey, L.N.; O'Donnell, C.J.; Graziani, E.I. Development of solid-phase site-specific conjugation and its application towards generation of dual labeled antibody and Fab drug conjugates. Bioconjugate Chemistry, 2016, 27(4), 1030–1039. doi: 10.1021/acs.bioconjchem.6b00054
  10. Stone, R.C.; Fellows, B.D.; Qi, B.; Trebatowski, D.; Jenkins, B.; Raval, Y.; Tzeng, T.R.; Bruce, T.F.; Mcnealy, T.; Austin, M.J.; Monson, T.C.; Huber, D.L.; Mefford, O.T. Highly Stable Multi-Anchored Magnetic Nanoparticles for Optical Imaging within Biofilms. Journal of Colloid and Interface Science, 2015, 459, 175–182. doi: 10.1016/j.jcis.2015.08.012
  11. Zhong, J.; Li, L.; Zhu, X.; Guan, S.; Yang, Q.; Zhou, Z.; Zhang, Z.; Huang, Y. A smart polymeric platform for multistage nucleus-targeted anticancer drug delivery. Biomaterials, 2015, 65, 43–55. doi: 10.1016/j.biomaterials.2015.06.042
  12. Li, G.; Xing, Y.; Wang, J.; Conti, P.S.; Chen, K. Near-infrared fluorescence imaging of CD13 receptor expression using a novel Cy5.5-labeled dimeric NGR peptide. Amino Acids, 2014, 46(6), 1547-1556. doi: 10.1007/s00726-014-1727-x
  13. Morton, S.W.; Zhao, X.; Quadir, M.A.; Hammond, P.T. FRET-enabled biological characterization of polymeric micelles. Biomaterials, 2014, 35(11), 3489-3496. doi: 10.1016/j.biomaterials.2014.01.027
  14. Chan, L.J.; Smith, C.M.; Chua, B.E.; Lin, F.; Bathgate, R.A.D.; Separovic, F.; Gundlach, A.L.; Hossain, M.A.; Wade, J.D. Synthesis of fluorescent analogs of relaxin family peptides and their preliminary in vitro and in vivo characterization. Frontiers in Chemistry, 2013, 1, Article 30. doi: 10.3389/fchem.2013.00030
  15. Astakhova, I.K.; Wengel, J. Interfacing Click Chemistry with Automated Oligonucleotide Synthesis for the Preparation of Fluorescent DNA Probes Containing Internal Xanthene and Cyanine Dyes. Chemistry - a European Journal, 2013, 19(3), 1112-1122. doi: 10.1002/chem.201202621
  16. Zolotarskaya, O.Y.; Wagner, A.F.; Beckta, J.M.; Valerie, K.; Wynne, K.J.; Yang, H. Synthesis of Water-Soluble Camptothecin-Polyoxetane Conjugates via Click Chemistry. Molecular Pharmaceutics, 2012, 9(11), 3403-3408. doi: 10.1021/mp3005066

Cyanine5.5 активированный эфир

  1. Chen, Y.; Fan, H.; Xu, C.; Hu, W.; Yu, B. Efficient Cholera Toxin B Subunit-Based Nanoparticles with MRI Capability for Drug Delivery to the Brain Following Intranasal Administration. Macromolecular Bioscience, in press. doi: 10.1002/mabi.201800340
  2. Nguyen, H.T.; Soe, Z.C.; Yang, K.Y.; Phung, C.D.; Nguyen, L.T-T.; Jeong, J.-H.; Jin, S.G.; Choi, H.-G.; Ku, S.K.; Yong, C.S.; Kim, J.O. Transferrin-conjugated pH-sensitive platform for effective delivery of porous palladium nanoparticles and paclitaxel in cancer treatment. Colloids and Surfaces, B: Biointerfaces, 2019, 176, 265–275. doi: 10.1016/j.colsurfb.2019.01.010
  3. Zhang, S.; Li, Z.-T.; Liu, M.; Wang, J.-R.; Xu, M.-Q.; Li, Z.-Y.; Duan, X.-C.; Hao, Y.-L.; Zheng, X.-C.; Li, H.; Feng, Z.-H.; Zhang, X. Anti-tumour activity of low molecular weight heparin doxorubicin nanoparticles for histone H1 high-expressive prostate cancer PC-3M cells. Journal of Controlled Release, 2019, 295, 102–117. doi: 10.1016/j.jconrel.2018.12.034
  4. Wang, Z.; Zhang, R.X.; Zhang, T.; He, C.; He, R.; Ju, X.; Wu, X.Y. In Situ Proapoptotic Peptide-Generating Rapeseed Protein-Based Nanocomplexes Synergize Chemotherapy for Cathepsin-B Overexpressing Breast Cancer. ACS Applied Materials & Interfaces, 2018, 10(48), 41056–41069. doi: 10.1021/acsami.8b14001
  5. Shih, F.-Y.; Su, I.-J.; Chu, L.-L.; Lin, X.; Kuo, S.-C.; Hou, Y.-C.; Chiang, Y.-T. Development of Pectin-Type B Gelatin Polyelectrolyte Complex for Curcumin Delivery in Anticancer Therapy. International Journal of Molecular Sciences, 2018, 19, E3625. doi: 10.3390/ijms19113625
  6. Li, L.; Liu, Y.; Li, H.; Guo, X.; He, X.; Geng, S.; Zhao, H.; Peng, X.; Shi, D.; Xiong, B.; Zhou, G.; Zhao, Y.; Zheng, C.; Yang, X. Rational design of temperature-sensitive blood-vessel-embolic nanogels for improving hypoxic tumor microenvironment after transcatheter arterial embolization. Theranostics, 2018, 8(22), 6291–6306. doi: 10.7150/thno.28845
  7. Zahid, M.; Feldman, K.S.; Garcia-Borrero, G.; Feinstein, T.N.; Pogodzinski, N.; Xu, X.; Yurko, R.; Czachowski, M.; Wu, Y.L.; Mason, N.S.; Lo, C.W. Cardiac Targeting Peptide, a Novel Cardiac Vector: Studies in Bio-Distribution, Imaging Application, and Mechanism of Transduction. Biomolecules, 2018, 8(4), 147. doi: 10.3390/biom8040147
  8. Bellat, V.; Ting, R.; Southard, T.L.; Vahdat, L.; Molina, H.; Fernandez, J.; Aras, O.; Stokol, T.; Law, B. Functional Peptide Nanofibers with Unique Tumor Targeting and Enzyme-Induced Local Retention Properties. Advanced Functional Materials, 2018, 28(44), 1803969. doi: 10.1002/adfm.201803969
  9. Moon, C.H.; Lee, J.Y.; Kim, E.S.; Park, J.H.; Kim, S.-Y.; Kim, J.Y.; Tchah, H. In vivo biodistribution of topical low molecular weight heparin-taurocholate in a neovascularized mouse cornea. International Journal of Ophthalmology, 2018, 11(9), 1435–1439. doi: 10.18240/ijo.2018.09.01
  10. Lv, J.; He, B.; Yu, J.; Wang, Y.; Wang, C.; Zhang, S.; Wang, H.; Hu, J.; Zhang, Q.; Cheng, Y. Fluoropolymers for intracellular and in vivo protein delivery. Biomaterials, 2018, 182, 167–175. doi: 10.1016/j.biomaterials.2018.08.023
  11. Machová, D.; Koziolová, E.; Chytil, P.; Venclíková, K.; Etrych, T.; Janoušková, O. Nanotherapeutics with suitable properties for advanced anticancer therapy based on HPMA copolymer-bound ritonavir via pH-sensitive spacers. European Journal of Pharmaceutics and Biopharmaceutics, 2018, 131, 141–150. doi: 10.1016/j.ejpb.2018.07.023
  12. Lu, Z.; Huang, F.-Y.; Cao, R.; Tan, G.-H.; Yi, G.; He, N.; Xu, L.; Zhang, L. Intrinsic, cancer cell-selective toxicity of organic photothermal nano-agent: a simple formulation for combined photothermal-chemotherapy of cancer. ACS Applied Materials & Interfaces, 2018, 10(31), 26028–26038. doi: 10.1021/acsami.8b07801
  13. Ruan, S.; Qin, L.; Xiao, W.; Hu, C.; Zhou, Y.; Wang, R.; Sun, X.; Yu, W.; He, Q.; Gao, H. Acid-Responsive Transferrin Dissociation and GLUT Mediated Exocytosis for Increased Blood-Brain Barrier Transcytosis and Programmed Glioma Targeting Delivery. Advanced Functional Materials, 2018, 28(30), 1802227. doi: 10.1002/adfm.201802227
  14. Wu, C.; Li, J.; Wang, W.; Hammond, P.T. Rationally Designed Polycationic Carriers for Potent Polymeric siRNA-Mediated Gene Silencing. ACS Nano, 2018, 12(7), 6504–6514. doi: 10.1021/acsnano.7b08777
  15. Liu, H.-J.; Luan, X.; Feng, H.-Y.; Dong, X.; Yang, S.-C.; Chen, Z.-J.; Cai, Q.-Y.; Lu, Q.; Zhang, Y.; Sun, P.; Zhao, M.; Chen, H.-Z.; Lovell, J.F.; Fang, C. Integrated Combination Treatment Using a "Smart" Chemotherapy and MicroRNA Delivery System Improves Outcomes in an Orthotopic Colorectal Cancer Mode. Advanced Functional Materials, 2018, 28(28), 1801118. doi: 10.1002/adfm.201801118
  16. Chen, J.; Zhou, J.; Gao, Z.; Li, X.; Wang, F.; Duan, X.; Li, G.; Joshi, B.; Kuick, R.D.; Appelman, H.D.; Wang, T. Multiplexed Targeting of Barrett's Neoplasia with a Heterobivalent Ligand: Imaging Study on Mouse Xenograft In Vivo and Human Specimens Ex Vivo. Journal of Medicinal Chemistry, 2018, 61(12), 5323–5331. doi: 10.1021/acs.jmedchem.8b00405
  17. Yang, Y.; Chen, Q.; Li, S.; Ma, W.; Yao, G.; Ren, F.; Cai, Z.; Zhao, P.; Liao, G.; Xiong, J.; Yu, Z. iRGD-Mediated and Enzyme-Induced Precise Targeting and Retention of Gold Nanoparticles for the Enhanced Imaging and Treatment of Breast Cancer. Journal of Biomedical Nanotechnology, 2018, 14(8), 1396–1408. doi: 10.1166/jbn.2018.2592
  18. Chiang, Y.-T.; Lyu, S.-Y.; Wen, Y.-H.; Lo, C.-L. Preparation and Characterization of Electrostatically Crosslinked Polymer-Liposomes in Anticancer Therapy. International Journal of Molecular Sciences, 2018, 19(6), 1615. doi: 10.3390/ijms19061615
  19. Balke, J.; Volz, P.; Neumann, F.; Brodwolf, R.; Wolf, A.; Pischon, H.; Radbruch, M.; Mundhenk, L.; Gruber, A.D.; Ma, N.; Alexiev, U. Visualizing Oxidative Cellular Stress Induced by Nanoparticles in the Subcytotoxic Range Using Fluorescence Lifetime Imaging. Small, 2018, 14(23), 1800310. doi: 10.1002/smll.201800310
  20. Cun, X.; Li, M.; Wang, S.; Wang, Y.; Wang, J.; Lu, Z.; Yang, R.; Tang, X.; Zhang, Z.; He, Q. A size switchable nanoplatform for targeting the tumor microenvironment and deep tumor penetration. Nanoscale, 2018, 10(21), 9935–9948. doi: 10.1039/c8nr00640g
  21. Akentieva, N.P.; Shushanov, S.S. Visualization of Ovarian Cancer Cells with Peptide VEGEGEEGEEY. Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology, 2018, 12(2), 189–198. doi: 10.1134/s1990747818020022
  22. Chen, C.C.; Stark, M.; Baikoghli, M.; Cheng, R.H. Surface Functionalization of Hepatitis E Virus Nanoparticles Using Chemical Conjugation Methods. Journal of Visualized Experiments, 2018, 135, e57020. doi: 10.3791/57020
  23. Wang, H.; Dai, T.; Li, S.; Zhou, S.; Yuan, X.; You, J.; Wang, C.; Mukwaya, V.; Zhou, G.; Liu, G.; Wei, X.; Dou, H. Scalable and cleavable polysaccharide nanocarriers for the delivery of chemotherapy drugs. Acta Biomaterialia, 2018, 72, 206–216. doi: 10.1016/j.actbio.2018.03.024
  24. Li, L.; Wang, C.; Huang, Q.; Xiao, J.; Zhang, Q.; Cheng, Y. A Degradable Hydrogel formed by Dendrimer-encapsulated Platinum Nanoparticle and Oxidized Dextran for Repeated Photothermal Cancer Therapy. Journal of Materials Chemistry B, 2018, 6(16), 2474–2480. doi: 10.1039/C8TB00091C
  25. He, H.; Chen, Y.; Li, Y.; Song, Z.; Zhong, Y.; Zhu, R.; Cheng, J.; Yin, L. Effective and Selective Anti-Cancer Protein Delivery via All-Functions-in-One Nanocarriers Coupled with Visible Light-Responsive, Reversible Protein Engineering. Advanced Functional Materials, 2018, 28(14), 1706710. doi: 10.1002/adfm.201706710
  26. Yang, W.; Cao, Y.; Zhang, Z.; Du, F.; Shi, Y.; Li, X.; Zhang, Q. Targeted delivery of FGF2 to subchondral bone enhanced the repair of articular cartilage defect. Acta Biomaterialia, 2018, 69, 170–182. doi: 10.1016/j.actbio.2018.01.039
  27. Alric, C.; Hervé-Aubert, K.; Aubrey, N.; Melouk, S.; Lajoie, L.; Même, W.; Même, S.; Courbebaisse, Y.; Ignatova, A.A.; Feofanov, A.V.; Chourpa, I.; Allard-Vannier, E. Targeting HER2-breast tumors with scFv-decorated bimodal nanoprobes. Journal of Nanobiotechnology, 2018, 16, 18. doi: 10.1186/s12951-018-0341-6
  28. Jasinski, D.L.; Yin, H.; Li, Z.; Guo, P. The Hydrophobic Effect from Conjugated Chemicals or Drugs on in Vivo Biodistribution of RNA Nanoparticles. Human Gene Therapy, 2018, 29(1), 77–86. doi: 10.1089/hum.2017.054
  29. Park, J.; Hwang, S.R.; Choi, J.U.; Alam, F.; Byun, Y. Self-assembled nanocomplex of PEGylated protamine and heparin–suramin conjugate for accumulation at the tumor site. International Journal of Pharmaceutics, 2018, 535(1–2), 38–46. doi: 10.1016/j.ijpharm.2017.10.055
  30. Kim, H.; Shin, K.; Park, O.K.; Choi, D.; Kim, H.D.; Baik, S.; Lee, S.H.; Kwon, S.-H.; Yarema, K.J.; Hong, J.; Hyeon, T.; Hwang, N.S. General and Facile Coating of Single Cells via Mild Reduction. Journal of the American Chemical Society, 2018, 140(4), 1199–1202. doi: 10.1021/jacs.7b08440
  31. Chen, J.; Ding, J.; Wang, Y.; Cheng, J.; Ji, S.; Zhuang, X.; Chen, X. Sequentially Responsive Shell-Stacked Nanoparticles for Deep Penetration into Solid Tumors. Advanced Materials, 2017, 29(32), 1701170. doi: 10.1002/adma.201701170
  32. Zhou, Z.; Jafari, M.; Sriram, V.; Kim, J.; Lee, J.-Y.; Ruiz-Torres, S.J.; Waltz, S.E. Delayed Sequential Co-Delivery of Gefitinib and Doxorubicin for Targeted Combination Chemotherapy. Molecular Pharmaceutics, 2017, 14(12), 4551–4559. doi: 10.1021/acs.molpharmaceut.7b00669
  33. Zhou, J.; He, L.; Pang, Z.; Appelman, H.D.; Kuick, R.; Beer, D.G.; Li, M.; Wang, T.D. Identification and validation of FGFR2 peptide for detection of early Barrett's neoplasia. Oncotarget, 2017, 8(50), 87095–87106. doi: 10.18632/oncotarget.19764
  34. Liu, Y.; Ji, X.; Liu, J.; Tong, W.W.L.; Askhatova, D.; Shi, J. Tantalum Sulfide Nanosheets as a Theranostic Nanoplatform for Computed Tomography Imaging-Guided Combinatorial Chemo-Photothermal Therapy. Advanced Functional Materials, 2017, 27(39), 1703261. doi: 10.1002/adfm.201703261
  35. Li, Y.; Han, Z.; Roelle, S.; DeSanto, A.; Sabatelle, R.; Schur, R.; Lu, Z.-R. Synthesis and Assessment of Peptide Gd-DOTA Conjugates Targeting Extradomain B Fibronectin for Magnetic Resonance Molecular Imaging of Prostate Cancer. Molecular Pharmaceutics, 2017, 14(11), 3906–3915. doi: 10.1021/acs.molpharmaceut.7b00619
  36. Xiao, W.; Ruan, S.; Yu, W.; Wang, R.; Hu, C.; Liu, R.; Gao, H. Normalizing tumor vessels to increase the enzyme-induced retention and targeting of gold nanoparticle for breast cancer imaging and treatment. Molecular Pharmaceutics, 2017, 14(10), 3489–3498. doi: 10.1021/acs.molpharmaceut.7b00475
  37. Xu, W.; Ding, J.; Chen, X. Reduction-Responsive Polypeptide Micelles for Intracellular Delivery of Antineoplastic Agent. Biomacromolecules, 2017, 18(10), 3291–3301. doi: 10.1021/acs.biomac.7b00950
  38. Han, Z.; Wu, X.; Roelle, S.; Chen, C.; Schiemann, W.P.; Lu, Z.-R. Targeted gadofullerene for sensitive magnetic resonance imaging and risk-stratification of breast cancer. Nature Communications, 2017, 8, 692. doi: Nature Communications
  39. Machado, Y.; Duinkerken, S.; Hoepflinger, V.; Mayr, M.; Korotchenko, E.; Kurtaj, A.; Pablos, I.; Steiner, M.; Stoecklinger, A.; Lübbers, J.; Schmid, M.; Ritter, U.; Scheiblhofer, S.; Ablinger, M.; Wally, V.; Hochmann, S.; Raninger, A.M.; Strunk, D.; van Kooyk, Y.; Thalhamer, J.; Weiss, R. Synergistic effects of dendritic cell targeting and laser-microporation on enhancing epicutaneous skin vaccination efficacy. Journal of Controlled Release, 2017, 266, 87–99. doi: 10.1016/j.jconrel.2017.09.020
  40. Park, J.; Choi, J.U.; Kim, K.; Byun, Y. Bile acid transporter mediated endocytosis of oral bile acid conjugated nanocomplex. Biomaterials, 2017, 147, 145–154. doi: 10.1016/j.biomaterials.2017.09.022
  41. Chen, Z.; Zhai, M.; Xie, X.Y.; Zhang, Y.; Ma, S.; Li, Z.; Yu, F.; Zhao, B.; Zhang, M.; Yang, Y.; Mei, X. Apoferritin Nanocage for Brain Targeted Doxorubicin Delivery. Molecular Pharmaceutics, 2017, 14(9), 3087–3097. doi: 10.1021/acs.molpharmaceut.7b00341
  42. Wang, H.; Chen, J.; Xu, C.; Shi, L.; Tayier, M.; Zhou, J.; Zhang, J.; Wu, J.; Ye, Z.; Fang, T.; Han, W. Cancer Nanomedicines Stabilized by π–π Stacking between Heterodimeric Prodrugs Enable Exceptionally High Drug Loading Capacity and Safer Delivery of Drug Combinations. Theranostics, 2017, 7(15), 3639–3652. doi: 10.7150/thno.20028
  43. Fu, L.; Han, L.; Xie, C.; Li, W.; Lin, L.; Pan, S.; Zhou, Y.; Li, Z.; Jin, M.; Zhang, A. Identification of Extracellular Actin As a Ligand for Triggering Receptor Expressed on Myeloid Cells-1 Signaling. Frontiers in Immunology, 2017, 8, 917. doi: 10.3389/fimmu.2017.00917
  44. Zhou, Z.; Kennell, C.; Jafari, M.; Lee, J.-Y.; Ruiz-Torres, S.J.; Waltz, S.E.; Lee, J.-H. Sequential Delivery of Erlotinib and Doxorubicin for Enhanced Triple Negative Breast Cancer Treatment Using Polymeric Nanoparticle. International Journal of Pharmaceutics, 2017, 530(1–2), 300–307. doi: 10.1016/j.ijpharm.2017.07.085
  45. Tsai, M.-H.; Pan, C.-H.; Peng, C.-L.; Shieh, M.-J. Panitumumab-Conjugated Pt-Drug Nanomedicine for Enhanced Efficacy of Combination Targeted Chemotherapy against Colorectal Cancer. Advanced Healthcare Materials, 2017, 6(13), 1700111. doi: 10.1002/adhm.201700111
  46. Han, S.; Son, H.Y.; Kang, B.; Jang, E.; Ki, J.; Lee, N.G.; Park, J.; Shin, M.-K.; Mun, B.; Min, J.-K.; Haam, S. Fluorescent nanoswitch for monitoring specific pluripotency-related microRNAs of induced pluripotent stem cells: Development of polyethyleneimineoligonucleotide hybridization probes. Nano Research, 2017, 10(8), 2545–2559. doi: 10.1007/s12274-016-1403-4
  47. Xu, X.; Saw, P.E.; Tao, W.; Li, Y.; Ji, X.; Yu, M.; Mahmoudi, M.; Rasmussen, J.; Ayyash, D.; Zhou, Y.; Farokhzad, O.C.; Shi, J. Tumor Microenvironment-Responsive Multistaged Nanoplatform for Systemic RNAi and Cancer Therapy. Nano Letters, 2017, 17(7), 4427–4435. doi: 10.1021/acs.nanolett.7b01571
  48. Ruan, S.; Xiao, W.; Hu, C.; Zhang, H.; Rao, J.; Wang, S.; Wang, X.; He, Q.; Gao, H. Ligand Mediated and Enzyme-Directed Precise Targeting and Retention for Enhanced Treatment of Glioblastoma. ACS Applied Materials & Interfaces, 2017, 9(24), 20348–20360. doi: 10.1021/acsami.7b02303
  49. Zhou, Z.; Yan, Y.; Hu, K.; Zou, Y.; Li, Y.; Ma, R.; Zhang, Q.; Cheng, Y. Autophagy inhibition enabled efficient photothermal therapy at a mild temperature. Biomaterials, 2017, 141, 116–124. doi: 10.1016/j.biomaterials.2017.06.030
  50. Yang, H.Y.; Jang, M.-S.; Li, Y.; Lee, J.H.; Lee, D.S. Multifunctional and Redox-Responsive Self-Assembled Magnetic Nanovectors for Protein Delivery and Dual-Modal Imaging. ACS Applied Materials & Interfaces, 2017, 9(22), 19184–19192. doi: 10.1021/acsami.7b03747
  51. Sun, W.; Li, L.; Yang, Q.-Q.; Zhang, Z.-R.; Huang, Y. Two birds, one stone: dual targeting of the cancer cell surface and subcellular mitochondria by the galectin-3-binding peptide G3-C12. Acta Pharmacologica Sinica, 2017, 38(6), 806–822. doi: 10.1038/aps.2016.137
  52. Lee, Y.; Kischuk, E.; Crist, S.; Ratliff, T.L.; Thompson, D.H. Targeting and Internalization of Liposomes by Bladder Tumor Cells Using a Fibronectin Attachment Protein-Derived Peptide–Lipopolymer Conjugate. Bioconjugate Chemistry, 2017, 28(5), 1481–1490. doi: 10.1021/acs.bioconjchem.7b00153
  53. Zhang, K.; Zhang, Y.; Li, Z.; Li, N.; Feng, N. Essential oil-mediated glycerosomes increase transdermal paeoniflorin delivery: optimization, characterization, and evaluation in vitro and in vivo. International Journal of Nanomedicine, 2017, 12, 3521–3532. doi: 10.2147/ijn.s135749
  54. Lee, J.Y.; Kim, S.E.; Yun, Y.-P.; Choi, S.-W.; Jeon, D.-I.; Kim, H.-J.; Park, K.; Song, H.-R. Osteogenesis and new bone formation of alendronate-immobilized porous PLGA microspheres in a rat calvarial defect model. Journal of Industrial and Engineering Chemistry, 2017, 52, 277–286. doi: 10.1016/j.jiec.2017.03.057
  55. Balasso, A.; Salmaso, S.; Pontisso, P.; Rosato, A.; Quarta, S.; Malfanti, A.; Mastrotto, F.; Caliceti, P. Re-programming pullulan for targeting and controlled release of doxorubicin to the hepatocellular carcinoma cells. European Journal of Pharmaceutical Sciences, 2017, 103, 104–115. doi: 10.1016/j.ejps.2017.02.016
  56. Yang, X.; Wang, Z.; Xiang, Z.; Li, D.; Hu, Z.; Cui, W.; Geng, L.; Fang, Q. Peptide probes derived from pertuzumab by molecular dynamics modeling for HER2 positive tumor imaging. PLoS Computational Biology, 2017, 13(4), e1005441. doi: 10.1371/journal.pcbi.1005441
  57. Han, Z.; Li, Y.; Roelle, S.; Zhou, Z.; Liu, Y.; Sabatelle, R.; DeSanto, A.; Yu, X.; Zhu, H.; Magi-Galluzzi, C.; Lu, Z.-R. A Targeted Contrast Agent Specific to an Oncoprotein in Tumor Microenvironment with the Potential for Detection and Risk Stratification of Prostate Cancer with MRI. Bioconjugate Chemistry, 2017, 28(4), 1031–1040. doi: 10.1021/acs.bioconjchem.6b00719
  58. Taskova, M.; Uhd, J.; Miotke, L.; Kubit, M.; Bell, J.; Ji, H.P.; Astakhova, K. Tandem Oligonucleotide Probe Annealing and Elongation To Discriminate Viral Sequence. Analytical Chemistry, 2017, 89(8), 4363–4366. doi: 10.1021/acs.analchem.7b00646
  59. Perillo, E.; Hervé-Aubert, K.; Allard-Vannier, E.; Falanga, A.; Galdiero, S.; Chourpa, I. Synthesis and in vitro evaluation of fluorescent and magnetic nanoparticles functionalized with a cell penetrating peptide for cancer theranosis. Journal of Colloid and Interface Science, 2017, 499, 209–217. doi: 10.1016/j.jcis.2017.03.106
  60. Pan, Y.; Ren, X.; Wang, S.; Li, X.; Luo, X.; Yin, Z. Annexin V-Conjugated Mixed Micelles as a Potential Drug Delivery System for Targeted Thrombolysis. Biomacromolecules, 2017, 18(3), 865–876. doi: 10.1021/acs.biomac.6b01756
  61. Alqahtani, M.S.; Islam, M.S.; Podaralla, S.; Kaushik, R.S.; Reineke, J.J.; Woyengo, T.; Perumal, O. Food Protein-based Core-Shell Nanocarriers for Oral Drug Delivery: Effect of Shell Composition on in-vitro and in-vivo Functional Performance of Zein Nanocarriers. Molecular Pharmaceutics, 2017, 14(3), 757–769. doi: 10.1021/acs.molpharmaceut.6b01017
  62. Mandracchia, D.; Rosato, A.; Trapani, A.; Chlapanidas, T.; Montagner, I.M.; Perteghella, S.; Di Franco, C.; Torre, M.L.; Trapani, G.; Tripodo, G. Design, synthesis and evaluation of biotin decorated inulin-based polymeric micelles as long-circulating nanocarriers for targeted drug delivery. Nanomedicine: Nanotechnology, Biology, and Medicine, 2017, 13(3), 1245–1254. doi: 10.1016/j.nano.2017.01.001
  63. Zhao, Lei and Chen, Guojun and Li, Jun and Fu, Yingmei and Mavlyutov, Timur A. and Yao, Annie and Nickells, Robert W. and Gong, Shaoqin and Guo, Lian-Wang. An intraocular drug delivery system using targeted nanocarriers attenuates retinal ganglion cell degeneration. Journal of Controlled Release, 2017, 247, 153–166. doi: 10.1016/j.jconrel.2016.12.038
  64. Braunová A.; Kostka, L.; Sivák, L.; Cuchalová, L.; Hvězdová, Z.; Laga, R.; Filippov, S.; Černoch, P.; Pechar, M.; Janoušková, O.; Šírová, M.; Etrych, T. Tumor-targeted micelle-forming block copolymers for overcoming of multidrug resistance. Journal of Controlled Release, 2017, 245, 41–51. doi: 10.1016/j.jconrel.2016.11.020
  65. Suarato, G.; Lee, S.-I.; Li, W.; Rao, S.; Khan, T.; Meng, Y.; Shelly, M. Micellar nanocomplexes for biomagnetic delivery of intracellular proteins to dictate axon formation during neuronal development. Biomaterials, 2017, 112, 176–191. doi: 10.1016/j.biomaterials.2016.09.035
  66. Yang, Q.; Wu, L.; Li, L.; Zhou, Z.; Huang, Y. Subcellular co-delivery of two different site-oriented payloads for tumor therapy. Nanoscale, 2017, 9(4), 1547–1558. doi: 10.1039/c6nr08200a
  67. Beldman, T.J.; Senders, M.L.; Alaarg, A.; Perez-Medina, C.; Tang, J.; Zhao, Y.; Fay, F.; Deichmöller, J.; Born, B.; Desclos, E.; van der Wel, N.N.; Hoebe, R.A.; Kohen, F.; Kartvelishvily, E.; Neeman, M.; Reiner, T.; Calcagno, C.; Fayad, Z.A.; de Winther, M.P.J.; Lutgens, E.; Mulder, W.J.M.; Kluza, E. Hyaluronan Nanoparticles Selectively Target Plaque-Associated Macrophages and Improve Plaque Stability in Atherosclerosis. ACS Nano, 2017, 11(6), 5785–5799. doi: 10.1021/acsnano.7b01385
  68. Zhou, Z.; Liu, Y.; Wu, L.; Li, L.; Huang, Y. Enhanced nuclear delivery of anti-cancer drugs using micelles containing releasable membrane fusion peptide and nuclear-targeting retinoic acid. Journal of Materials Chemistry B, 2017, 5(34), 7175–7185. doi: 10.1039/C7TB01177F
  69. Poh, S.; Putt, K.S.; Low, P.S. Folate-targeted dendrimers selectively accumulate at sites of inflammation in mouse models of ulcerative colitis and atherosclerosis. Biomacromolecules, 2017, 18(10), 3082–3088. doi: 10.1021/acs.biomac.7b00728
  70. Cao, T.; Zhou, X.; Zheng, Y.; Sun, Y.; Zhang, J.; Chen, W.; Zhang, J.; Zhou, Z.; Yang, S.-P.; Zhang, Y.; Yang, H.; Wang, M.-W. Chelator-Free Conjugation of 99mTc and Gd3+ to PEGylated Nanographene Oxide for Dual-modality SPECT/MR Imaging of Lymph Nodes. ACS Applied Materials & Interfaces, 2017, 9(49), 42612–42621. doi: 10.1021/acsami.7b14836
  71. Koziolová, E.; Machová, D.; Pola, R.; Janoušková, O.; Chytil, P.; Laga, R.; Filippov, S.K.; Šubr, V.; Etrych, T.; Pechar, M. Micelle-forming HPMA copolymer conjugates of ritonavir bound via a pH-sensitive spacer with improved cellular uptake designed for enhanced tumor accumulation. Journal of Materials Chemistry B, 2016, 4(47), 7620–7629. doi: 10.1039/C6TB02225A
  72. Yan, Y.; Liu, L.; Xiong, H.; Miller, J.B.; Zhou, K.; Kos, P.; Huffman, K.E.; Elkassih, S.; Norman, J.W.; Carstens, R.; Kim, J.; Minna, J.D.; Siegwart, D.J. Functional polyesters enable selective siRNA delivery to lung cancer over matched normal cells. Proceedings of the National Academy of Sciences of the U.S.A., 2016, 113(39), E5702–E5710. doi: 10.1073/pnas.1606886113
  73. Cao, T.; You, P.; Zhou, X.; Luo, J.; Xu, X.; Zhou, Z.; Yang, S.; Zhang, Y.; Yang, H.; Wang, M. Visualization of size-dependent tumour retention of PEGylated nanographene oxide via SPECT imaging. Journal of Materials Chemistry B, 2016, 4(39), 6446–6453. doi: 10.1039/c6tb01892k
  74. Ye, Y.; Wang, J.; Hu, Q.; Hochu, G.M.; Xin, H.; Wang, C.; Gu, Z. Synergistic Transcutaneous Immunotherapy Enhances Antitumor Immune Responses through Delivery of Checkpoint Inhibitors. ACS Nano, 2016, 10(9), 8956–8963. doi: 10.1021/acsnano.6b04989
  75. Chen, Y.; Li, Y.; Shen, W.; Li, K.; Yu, L.; Chen, Q.; Ding, J. Controlled release of liraglutide using thermogelling polymers in treatment of diabetes. Scientific Reports, 2016, 6, 31593. doi: 10.1038/srep31593
  76. Sun, Y.; Hong, S.; Ma, X.; Cheng, K.; Wang, J.; Zhang, Z.; Yang, M.; Jiang, Y.; Hong, X.; Cheng, Z. Recyclable Cu(I)/Melanin Dots for Cycloadditions, Bioconjugation and Cell Labeling. Chemical Science, 2016, 7(9), 5888–5892. doi: 10.1039/c6sc01536k
  77. Jiang, X.; Bugno, J.; Hu, C.; Yang, Y.; Herold, T.; Qi, J.; Chen, P.; Gurbuxani, S.; Arnovitz, S.; Strong, J.; Ferchen, K.; Ulrich, B.; Weng, H.; Wang, Y.; Huang, H.; Li, S.; Neilly, M.B.; Larson, R.A.; Le Beau, M.M.; Bohlander, S.K.; Jin, J.; Li, Z.; Bradner, J.E.; Hong, S.; Chen, J. Eradication of acute myeloid leukemia with FLT3 ligand-targeted miR-150 nanoparticles. Cancer Research, 2016, 76(15), 4470–4480. doi: 10.1158/0008-5472.CAN-15-2949
  78. Zhang, Y.; Li, Z.; Zhang, K.; Yang, G.; Wang, Z.; Zhao, J.; Hu, R.; Feng, N. Ethyl oleate-containing nanostructured lipid carriers improve oral bioavailability of trans-ferulic acid ascompared with conventional solid lipid nanoparticles. International Journal of Pharmaceutics, 2016, 511(1), 57–64. doi: 10.1016/j.ijpharm.2016.06.131
  79. Wang, C.; Wang, X.; Dong, K.; Luo, J.; Zhang, Q.; Cheng, Y. Injectable and Responsively Degradable Hydrogel for Personalized Photothermal Therapy. Biomaterials, 2016, 104, 129–137. doi: 10.1016/j.biomaterials.2016.07.013
  80. Kim, K.-M.; Kim, M.K.; Paek, H.-J.; Choi, S.-J.; Oh, J.-M. Stable fluorescence conjugation of ZnO nanoparticles and their size dependent cellular uptake. Colloids and Surfaces B: Biointerfaces, 2016, 145, 870–877. doi: 10.1016/j.colsurfb.2016.06.006
  81. Geng, L.; Wang, Z.; Jia, X.; Han, Q.; Xiang, Z.; Li, D.; Yang, X.; Zhang, D.; Bu, X.; Wang, W.; Hu, Z.; Fang, Q. HER2 Targeting Peptides Screening and Applications in Tumor Imaging and Drug Delivery. Theranostics, 2016, 6(8), 1261–1273. doi: 10.7150/thno.14302
  82. Yang, Q.; Li, L.; Sun, W.; Zhou, Z.; Huang, Y. Dual Stimuli-Responsive Hybrid Polymeric Nanoparticles Self-Assembled from POSS-Based Star-Like Copolymer-Drug Conjugates for Efficient Intracellular Delivery of Hydrophobic Drugs. ACS Applied Materials & Interfaces, 2016, 8(21), 13251–13261. doi: 10.1021/acsami.6b02403
  83. Brinkman, A.M.; Chen, G.; Wang, Y.; Hedman, C.J.; Sherer, N.M.; Havighurst, T.C.; Gong, S.; Xu, W. Aminoflavone-Loaded EGFR-Targeted Unimolecular Micelle Nanoparticles Exhibit Anti-Cancer Effects in Triple Negative Breast Cancer. Biomaterials, 2016, 101, 20–31. doi: 10.1016/j.biomaterials.2016.05.041
  84. Bygd, H.C.; Bratlie, K.M. The effect of chemically modified alginates on macrophage phenotype and biomolecule transport. Journal of Biomedical Materials Research, 2016, 104(7), 1707–1719. doi: 10.1002/jbm.a.35700
  85. Zhao, L.; Yuan, W.; Ang, C.Y.; Qu, Q.; Dai, Y.; Gao, Y.; Luo, Z.; Wang, J.; Chen, H.; Li, M.; Li, F.; Zhao, Y. Silica-Polymer Hybrid with Self-Assembled PEG Corona Excreted Rapidly via a Hepatobiliary Route. Advanced Functional Materials, 2016, 26(18), 3036–3047. doi: 10.1002/adfm.201505155
  86. Al-Hilal, T.A.; Chung, S.W.; Choi, J.U.; Alam, F.; Park, J.; Kim, S.W.; Kim, S.Y.; Ahsan, F.; Kim, I.-S.; Byun, Y. Targeting prion-like protein doppel selectively suppresses tumor angiogenesis. Journal of Clinical Investigation, 2016, 126(4), 1251–1266. doi: 10.1172/JCI83427
  87. Jiang, X.; Hu, C.; Arnovitz, S.; Bugno, J.; Yu, M.; Zuo, Z.; Chen, P.; Huang, H.; Ulrich, B.; Gurbuxani, S.; Weng, H.; Strong, J.; Wang, Y.; Li, Y.; Salat, J.; Li, S.; Elkahloun, A.G.; Yang, Y.; Neilly, M.B.; Larson, R.A.; Le Beau, M.M.; Herold, T.; Bohlander, S.K.; Liu, P.P.; Zhang, J.; Li, Z.; He, C.; Jin, J.; Hong, S.; Chen, J.;. miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia. Nature Communications, 2016, 7, 11452. doi: 10.1038/ncomms11452
  88. Kim, J.B.; Park, K.; Ryu, Ji.; Lee, J.J.; Lee, M.W.; Cho, H.S.; Nam, H.S.; Park, O.K.; Song, J.W.; Kim, T.S.; Oh, D.J.; Gweon, D.; Oh, W.-Y.; Yoo, H.; Kim, J.W. Intravascular optical imaging of high-risk plaques in vivo by targeting macrophage mannose receptors. Scientific Reports, 2016, 6, 22608. doi: 10.1038/srep22608
  89. Cai, X.; Jin, R.; Wang, J.; Yue, D.; Jiang, Q.; Wu, Y.; Gu, Z. Bioreducible Fluorinated Peptide Dendrimers Capable of Circumventing Various Physiological Barriers for Highly Efficient and Safe Gene Delivery. ACS Applied Materials & Interfaces, 2016, 8(9), 5821–5832. doi: 10.1021/acsami.5b11545
  90. Ma, G.; Zhao, Z.; Liu, H. Yeast Cells Encapsulating Polymer Nanoparticles as Trojan Particles via in Situ Polymerization inside Cells. Macromolecules, 2016, 49(5), 1545–1551. doi: 10.1021/acs.macromol.6b00016
  91. Rabinsky, E.F.; Joshi, B.P.; Pant, A.; Zhou, J.; Duan, X.; Smith, A.; Kuick, R.; Fan, S.; Nusrat, A.; Owens, S.R.; Appelman, H.D.; Wang, T.D. Overexpressed claudin-1 can be endoscopically visualized in colonic adenomas in vivo. CMGH Cellular and Molecular Gastroenterology and Hepatology, 2016, 2(2), 222–237. doi: 10.1016/j.jcmgh.2015.12.001
  92. Joshi, B.P.; Zhou, J.; Pant, A.; Duan, X.; Zhou, Q.; Kuick, R.; Owens, S.R.; Appelman, H.; Wang, T.D. Design and Synthesis of Near-Infrared Peptide for in Vivo Molecular Imaging of HER2. Bioconjugate Chemistry, 2016, 27(2), 481–494. doi: 10.1021/acs.bioconjchem.5b00565
  93. Khaliq, N.U.; Park, D.Y.; Lee, J.Y.; Joo, Y.; Oh, K.S.; Kim, J.S.; Kim, J.-S.; Kim, I.-S.; Kwon, I.C.; Yuk, S.H. The multilayer nanoparticles for deep penetration of docetaxel into tumor parenchyma to overcome tumor microenvironment. Colloids and Surfaces B: Biointerfaces, 2016, 146, 833–840. doi: 10.1016/j.colsurfb.2016.07.034
  94. Hu, H.; Li, Y.; Zhou, Q.; Ao, Y.; Yu, C.; Wan, Y.; Xu, H.-B.; Li, Z.; Yang, X. Redox-sensitive hydroxyethyl starch-doxorubicin conjugate for tumor targeted drug delivery. ACS Applied Materials & Interfaces, 2016, 8(45), 30833–30844. doi: 10.1021/acsami.6b11932
  95. Chen, Y.; Luan, J.; Shen, W.; Lei, K.; Yu, L.; Ding, J. Injectable and thermosensitive hydrogel containing liraglutide as a long-acting anti-diabetic system. ACS Applied Materials & Interfaces, 2016, 8(45), 30703–30713. doi: 10.1021/acsami.6b09415
  96. Alam, F.; Chung, S.W.; Hwang, S.R.; Kim, J.-y.; Park, J.; Moon, H.T.; Byun, Y. Preliminary safety evaluation of a taurocholate-conjugated low-molecular-weight heparin derivative (LHT7): a potent angiogenesis inhibitor. Journal of Applied Toxicology, 2015, 35(1), 104–115. doi: 10.1002/jat.2995
  97. Wang, H.; Li, D.; Liu, S.; Liu, R.; Yuan, H.; Krasnoperov, V.; Shan, H.; Conti, P.S.; Gill, P.S.; Li, Z. Small-Animal PET Imaging of Pancreatic Cancer Xenografts Using a 64Cu-Labeled Monoclonal Antibody, MAb159. Journal of Nuclear Medicine, 2015, 56(6), 908–913. doi: 10.2967/jnumed.115.155812
  98. Zhou, B.; Wang, H.; Liu, R.; Wang, M.; Deng, H.; Giglio, B.; Gill, P.S.; Shan, H.; Li, Z. PET Imaging of Dll4 Expression in Glioblastoma and Colorectal Cancer Xenografts Using 64Cu-Labeled Monoclonal Antibody 61B. Molecular Pharmaceutics, 2015, 12(10), 3527–3534. doi: 10.1021/acs.molpharmaceut.5b00105
  99. Geng, L.; Wang, Z.; Yang, X.; Li, D.; Lian, W.; Xiang, Z.; Wang, W.; Bu, X.; Lai, W.; Hu, Z.; Fang, Q. Structure-based Design of Peptides with High Affinity and Specificity to HER2 Positive Tumors. Theranostics, 2015, 5(10), 1154–1165. doi: 10.7150/thno.12398
  100. Chung, S.W.; Lee, B.S. Choi, J.U.; Kim, S.W.; Kim, I.-S.; Kim, S.Y.; Byun, Y. Optimization of a stable linker involved DEVD peptide-doxorubicin conjugate that is activated upon radiation-induced caspase-3-mediated apoptosis. Journal of Medicinal Chemistry, 2015, 58(16), 6435–6447. doi: 10.1021/acs.jmedchem.5b00420
  101. Li, L.; Sun, W.; Zhong, J.; Yang, Qi.; Zhu, X.; Zhou, Z.; Zhang Z.; Huang, Y. Multistage Nanovehicle Delivery System Based on Stepwise Size Reduction and Charge Reversal for Programmed Nuclear Targeting of Systemically Administered Anticancer Drugs. Advanced Functional Materials, 2015, 25(26), 4101–4113. doi: 10.1002/adfm.201501248
  102. Zhou, J.; Joshi, B.P.; Duan, X.; Pant, A.; Qiu, Z.; Kuick, R.; Owens, S.R.; Wang, T.D. EGFR Overexpressed in Colonic Neoplasia Can be Detected on Wide-Field Endoscopic Imaging. Clinical and Translational Gastroenterology, 2015, 6, e101. doi: 10.1038/ctg.2015.28
  103. Arami, H.; Khandhar, A.P.; Tomitaka, A.; Yu, E.; Goodwill, P.W.; Conolly, S.M.; Krishnan, K.M. In vivo multimodal magnetic particle imaging (MPI) with tailored magneto/optical contrast agents. Biomaterials, 2015, 52, 251–261. doi: 10.1016/j.biomaterials.2015.02.040
  104. Mahoney, D.; Owens, E.A.; Fan, C.; Hsiang, J.-C.; Henary, M.; Dickson, R.M. Tailoring Cyanine Dark States for Improved Optically Modulated Fluorescence Recovery. The Journal of Physical Chemistry B, 2015, 119(13), 4637–4643. doi: 10.1021/acs.jpcb.5b00777
  105. Bygd, H.C.; Forsmark, K.D.; Bratlie, K.M. Altering in vivo macrophage responses with modified polymer properties. Biomaterials, 2015, 56, 187–197. doi: 10.1016/j.biomaterials.2015.03.042
  106. Hou, Z.; Lin, J.; Li, Y.; Guo, F.; Yu, F.; Wu, H.; Fan, Z.; Zhi, L.; Luo, F. Validation of a dual role of methotrexate-based chitosan nanoparticles in vivo. RSC Advances, 2015, 5(52), 41393–41400. doi: 10.1039/c5ra03705K
  107. Ruan, S.; He, Q.; Gao, H. Matrix metalloproteinase triggered size-shrinkable gelatin-gold fabricated nanoparticles for tumor microenvironment sensitive penetration and diagnosis of glioma. Nanoscale, 2015, 7, 9487–9496. doi: 10.1039/c5nr01408e
  108. Kim, M.-G.; Park, J.Y.; Miao, W.; Lee, J.; Oh, Y.-K. Polyaptamer DNA nanothread-anchored, reduced graphene oxide nanosheets for targeted delivery. Biomaterials, 2015, 48, 129–136. doi: 10.1016/j.biomaterials.2015.01.009
  109. Cai, H.; Singh, A.N.; Sun, X.; Peng, F. Synthesis and Characterization of Her2-NLP Peptide Conjugates Targeting Circulating Breast Cancer Cells: Cellular Uptake and Localization by Fluorescent Microscopic Imaging. Journal of Fluorescence, 2015, 25(1), 113–117. doi: 10.1007/s10895-014-1486-9
  110. Yang, Q.; Li, L.; Zhu, X.; Sun, W.; Zhou, Z.; Huang, Y. The impact of the HPMA polymer structure on the targeting performance of the conjugated hydrophobic ligand. RSC Advances, 2015, 5(19), 14858–14870. doi: 10.1039/c4ra16085a
  111. Cai, L.; Dewi, R.E.; Heilshorn, S.C. Injectable Hydrogels with In Situ Double Network Formation Enhance Retention of Transplanted Stem Cells. Advanced Functional Materials, 2015, 25(9), 1344–1351. doi: 10.1002/adfm.201403631
  112. Jeong, J.-H. Molecular imaging monitoring of poly(ethylene glycol) conjugated islets for evaluation of islet graft rejection. Archives of Pharmacal Research, 2015, 38(5), 785–790. doi: 10.1007/s12272-014-0412-7
  113. Wang, X.; Huang, S.S.; Heston, W.D.W.; Guo, H.; Wang, B.-C.; Basilion, J.P. Development of Targeted Near-Infrared Imaging Agents for Prostate Cancer. Molecular Cancer Therapeutics, 2014, 13(11), 2595–2606. doi: 10.1158/1535-7163.mct-14-0422
  114. Kim, H.S.; Yoo, H.S. Surface-polymerized biomimetic nanofibrils for the cell-directed association of 3-D scaffolds. Chemical Communications, 2014, 51, 306–309. doi: 10.1039/c4cc06875k
  115. Al-Hilal, T.A.; Alam, F.; Park, J.W.; Kim, K.; Kwon, I.C.; Ryu, G.H.; Byun, Y. Prevention effect of orally active heparin conjugate on cancer-associated thrombosis. Journal of Controlled Release, 2014, 195, 155-161. doi: 10.1016/j.jconrel.2014.05.027
  116. Graen, T.M.D.; Hoefling, M.; Grubmüller, H. AMBER-DYES: Characterization of Charge Fluctuations and Force Field Parameterization of Fluorescent Dyes for Molecular Dynamics Simulations. Journal of Chemical Theory and Computation, 2014, 10(12), 5505-5512. doi: 10.1021/ct500869p
  117. Hu, S.-H.; Fang, R.-H.; Chen, Y.-W.; Liao, B.-J.; Chen, I.-W.; Chen, S.-Y. Photoresponsive Protein-Graphene-Protein Hybrid Capsules with Dual Targeted Heat-Triggered Drug Delivery Approach for Enhanced Tumor Therapy. Advanced Functional Materials, 2014, 24(26), 4144-4155. doi: 10.1002/adfm.201400080
  118. Lv, S.; Tang, Z.; Li, M.; Lin, J.; Song, W.; Liu, H.; Huang, Y.; Zhang, Y.; Chen, X. Co-delivery of doxorubicin and paclitaxel by PEG-polypeptide nanovehicle for the treatment of non-small cell lung cancer. Biomaterials, 2014, 35(23), 6118-6129. doi: 10.1016/j.biomaterials.2014.04.034
  119. Morton, S.W.; Lee, M.J.; Deng, Z.J.; Dreaden, E.C.; Siouve, E.; Shopsowitz, K.E.; Shah, N.J.; Yaffe, M.B.; Hammond, P.T. A Nanoparticle-Based Combination Chemotherapy Delivery System for Enhanced Tumor Killing by Dynamic Rewiring of Signaling Pathways. Science Signaling, 2014, 7(325), ra44-ra44. doi: 10.1126/scisignal.2005261
  120. Zou, Y.; Li, F.; Hou, W.; Sampath, P.; Zhang, Y.; Thorne, S.H. Manipulating the expression of chemokine receptors enhances delivery and activity of cytokine-induced killer cells. British Journal of Cancer, 2014, 110(8), 1992-1999. doi: 10.1038/bjc.2014.140
  121. Joshi, R.; Feldmann, V.; Koestner, W.; Detje, C.; Gottschalk, S.; Mayer, H.A.; Sauer, M.G.; Engelmann, J. Multifunctional silica nanoparticles for optical and magnetic resonance imaging. Biological Chemistry, 2013, 394(1), 125–135. doi: 10.1515/hsz-2012-0251
  122. Lee, A.; Chin, J.; Park, O.K.; Chung, H.; Kim, J.W.; Yoon, S.-Y.; Park, K. A novel near-infrared fluorescence chemosensor for copper ion detection using click ligation and energy transfer. Chemical Communications, 2013, 49, 5969–5971. doi: 10.1039/c3cc42059k
  123. Morton, S.W.; Herlihy, K.P.; Shopsowitz, K.E.; Deng, Z.J.; Chu, K.S.; Bowerman, C.J.; DeSimone, J.M.; Hammond, P.T. Scalable Manufacture of Built-to-Order Nanomedicine: Spray-Assisted Layer-by-Layer Functionalization of PRINT Nanoparticles. Advanced Materials, 2013, 25(34), 4707-4713. doi: 10.1002/adma.201302025
  124. Tang, H.; Sampath, P.; Yan, X.; Thorne, S.H. Potential for enhanced therapeutic activity of biological cancer therapies with doxycycline combination. Gene Therapy, 2013, 20(7), 770-778. doi: 10.1038/gt.2012.96
  125. Wang, C.; Ravi, S.; Garapati, U.S.; Das, M.; Howell, M.; Mallela, J.; Alwarappan, S.; Mohapatra, S.S.; Mohapatra, S. Multifunctional chitosan magnetic-graphene (CMG) nanoparticles: a theranostic platform for tumor-targeted co-delivery of drugs, genes and MRI contrast agents. Journal of Materials Chemistry B, 2013, 1(35), 4396-4396. doi: 10.1039/c3tb20452a
  126. Yuan, H.; Cho, H.; Chen, H.H.; Panagia, M.; Sosnovik, D.E.; Josephson, L. Fluorescent and radiolabeled triphenylphosphonium probes for imaging mitochondria. Chemical Communications, 2013, 49(88), 10361-10363. doi: 10.1039/c3cc45802d
  127. Liu, Z.; Miller, S.J.; Joshi, B.P.; Wang, T.D. In vivo targeting of colonic dysplasia on fluorescence endoscopy with near-infrared octapeptide. Gut, 2012, 62(3), 395-403. doi: 10.1136/gutjnl-2011-301913
  128. Adulnirath, A.; Chung, S.W.; Park, J.; Hwang, S.R.; Kim, J.-Y.; Yang, V.C.; Kim, S.Y.; Moon, H.T.; Byun, Y. Cyclic RGDyk-conjugated LMWH-taurocholate derivative as a targeting angiogenesis inhibitor. Journal of Controlled Release, 2012, 164(1), 8-16. doi: 10.1016/j.jconrel.2012.10.001
  129. Kim, J.-y.; Shim, G.; Choi, H.-w.; Park, J.; Chung, S.W.; Kim, S.; Kim, K.; Chan Kwon, I.; Kim, C.-W.; Kim, S.Y. et al. Tumor vasculature targeting following co-delivery of heparin-taurocholate conjugate and suberoylanilide hydroxamic acid using cationic nanolipoplex. Biomaterials, 2012, 33(17), 4424-4430. doi: 10.1016/j.biomaterials.2012.02.066
  130. Zhou, K.; Liu, H.; Zhang, S.; Huang, X.; Wang, Y.; Huang, G.; Sumer, B.D.; Gao, J. Multicolored pH-Tunable and Activatable Fluorescence Nanoplatform Responsive to Physiologic pH Stimuli. Journal of the American Chemical Society, 2012, 134(18), 7803-7811. doi: 10.1021/ja300176w

Cyanine5.5 алкин

  1. Mickuté, M.; Nainyté, M.; Vasiliauskaité, L.; Plotnikova, A.; Masevičius, V.; Klimašauskas, S.; Vilkaitis, G. Animal Hen1 2'-O-methyltransferases as tools for 3'-terminal functionalization and labelling of single-stranded RNAs. Nucleic Acids Research, 2018, 46(17), e104. doi: 10.1093/nar/gky514
  2. Yuan, H.; Wilks, M.Q.; Fakhri, G.E.; Normandin, M.D.; Kaittanis, C.; Josephson, L. Heat-induced-radiolabeling and click chemistry: A powerful combination for generating multifunctional nanomaterials. PLoS One, 2017, 12(2), e0172722. doi: 10.1371/journal.pone.0172722
  3. Duan, Z.; Zhang, Y.; Zhu, H.; Sun, L.; Cai, H.; Li, B.; Gong, Q.; Gu, Z.; Luo, K. Stimuli-Sensitive Biodegradable and Amphiphilic Block Copolymer-Gemcitabine Conjugates Self-assemble Into a Nanoscale Vehicle for Cancer Therapy. ACS Applied Materials & Interfaces, 2017, 9(4), 3474–3486. doi: 10.1021/acsami.6b15232
  4. Shi, Y.; van der Meel, R.; Theek, B.; Oude Blenke, E.; Pieters, E.H.E.; Fens, M.H.A.M.; Ehling, J.; Schiffelers, R.M.; Storm, G.; van Nostrum, C.F.; Lammers, T.; Hennink, W.E. Complete Regression of Xenograft Tumors upon Targeted Delivery of Paclitaxel via Π–Π Stacking Stabilized Polymeric Micelles. ACS Nano, 2015, 9(4), 3740–3752. doi: 10.1021/acsnano.5b00929

Cyanine5.5 амин

  1. Shim, K.-S.; Kim, H.-J.; Kim, S.E.; Park, K. Simple surface biofunctionalization of biphasic calcium phosphates for improving osteogenic activity and bone tissue regeneration. Journal of Industrial and Engineering Chemistry, 2018, 68, 228–228. doi: 10.1016/j.jiec.2018.07.048
  2. Qiao, R.; Esser, L.; Fu, C.; Zhang, C.; Hu, J.; Ramírez-García, P.; Li, Y.; Quinn, J.F.; Whittaker, M.R.; Whittaker, A.K.; Davis, T.P. Bioconjugation and Fluorescence Labelling of Iron Oxide Nanoparticles Grafted with Bromomaleimide-terminal Polymers. Biomacromolecules, 2018, 19(11), 4423–4429. doi: 10.1021/acs.biomac.8b01282
  3. Lee, S.Y.; Ko, S.-H.; Shim, J.-S.; Kim, D.-D.; Cho, H.-J. Tumor Targeting and Lipid Rafts Disrupting Hyaluronic Acid-Cyclodextrin-Based Nanoassembled Structure for Cancer Therapy. ACS Applied Materials & Interfaces, 2018, 10(43), 36628–36640. doi: 10.1021/acsami.8b08243
  4. Zhao, Y.; Fletcher, N.L.; Liu, T.; Gemmell, A.C.; Houston, Z.H.; Blakey, I.; Thurecht, K.J. In vivo therapeutic evaluation of polymeric nanomedicines: effect of different targeting peptides on therapeutic efficacy against breast cancer. Nanotheranostics, 2018, 2(4), 360–370. doi: 10.7150/ntno.27142
  5. Garcia, F.; Rippe, M.; Companhoni, M.V.; Stefanello, T.; Louage, B.; van Herck, S.; Sancey, L.; Coll, J.-L.; De Geest, B.; Nakamura, C.V.; Auzély-Velty, R. A versatile method for the selective core-crosslinking of hyaluronic acid-based nanogels via ketone-hydrazide chemistry: from chemical characterization to in vivo biodistribution. Biomaterials Science, 2018, 6(7), 1754–1763. doi: 10.1039/c8bm00396c
  6. Murata, H.; Carmali, S.; Baker, S.L.; Matyjaszewski, K.; Russell, A.J. Solid-phase synthesis of protein-polymers on reversible immobilization supports. Nature Communications, 2018, 9, 845. doi: 10.1038/s41467-018-03153-8
  7. Park, J.; Hwang, S.R.; Choi, J.U.; Alam, F.; Byun, Y. Self-assembled nanocomplex of PEGylated protamine and heparin–suramin conjugate for accumulation at the tumor site. International Journal of Pharmaceutics, 2018, 535(1–2), 38–46. doi: 10.1016/j.ijpharm.2017.10.055
  8. Park, J.; Choi, J.U.; Kim, K.; Byun, Y. Bile acid transporter mediated endocytosis of oral bile acid conjugated nanocomplex. Biomaterials, 2017, 147, 145–154. doi: 10.1016/j.biomaterials.2017.09.022
  9. Duret, D.; Grassin, A.; Henry, M.; Jacquet, T.; Thoreau, F.; Denis-Quanquin, S.; Coll, J.-L.; Boturyn, D.; Favier, A.; Charreyre, M.-T. "Polymultivalent" Polymer-Peptide Cluster Conjugates for an Enhanced Targeting of Cells Expressing αvβ3 Integrins. Bioconjugate Chemistry, 2017, 28(9), 2241–2245. doi: 10.1021/acs.bioconjchem.7b00362
  10. Luo, W.; Wen, G.; Yang, L.; Tang, J.; Wang, J.; Wang, J.; Zhang, S.; Zhang, L.; Ma, F.; Xiao, L.; Wang, Y.; Li, Y. Dual-targeted and pH-sensitive Doxorubicin Prodrug-Microbubble Complex with Ultrasound for Tumor Treatment. Theranostics, 2017, 7(2), 452–465
  11. Yang, X.; Wang, Z.; Zhang, F.; Zhu, G.; Song, J.; Teng, G.-J.; Niu, G.; Chen, X. Mapping Sentinel Lymph Node Metastasis by Dual-probe Optical Imaging. Theranostics, 2017, 7(1), 153–163. doi: 10.7150/thno.17085

Cyanine5.5 гидразид

  1. Machado, Y.; Duinkerken, S.; Hoepflinger, V.; Mayr, M.; Korotchenko, E.; Kurtaj, A.; Pablos, I.; Steiner, M.; Stoecklinger, A.; Lübbers, J.; Schmid, M.; Ritter, U.; Scheiblhofer, S.; Ablinger, M.; Wally, V.; Hochmann, S.; Raninger, A.M.; Strunk, D.; van Kooyk, Y.; Thalhamer, J.; Weiss, R. Synergistic effects of dendritic cell targeting and laser-microporation on enhancing epicutaneous skin vaccination efficacy. Journal of Controlled Release, 2017, 266, 87–99. doi: 10.1016/j.jconrel.2017.09.020
  2. Zhao, Y.; Wang, Y.; Ran, F.; Cui, Y.; Liu, C.; Zhao, Q.; Gao, Y.; Wang, D.; Wang, S. A comparison between sphere and rod nanoparticles regarding their in vivo biological behavior and pharmacokinetics. Scientific Reports, 2017, 7, 4131. doi: 10.1038/s41598-017-03834-2

Cyanine5.5 карбоновая кислота

  1. Zhang, L.; Yao, M.; Yan, W.; Liu, X.; Jiang, B.; Qian, Z.; Gao, Y.; Lu, X.-J.; Chen, X.; Wang, Q.-L. Delivery of a chemotherapeutic drug using novel hollow carbon spheres for esophageal cancer treatment. International Journal of Nanomedicine, 2017, 12, 6759–6769. doi: 10.2147/IJN.S142916
  2. Liu, M.; Richardson, R.R.; Mountford, S.J.; Zhang, L.; Tempone, M.H.; Herzog, H.; Holliday, N.D.; Thompson, P.E. Identification of a Cyanine-Dye Labelled Peptidic Ligand for Y1R and Y4R, based upon the Neuropeptide Y C-terminal analogue, BVD-15. Bioconjugate Chemistry, 2016, 27(9), 2166–2175. doi: 10.1021/acs.bioconjchem.6b00376
  3. Camerino, M.A.; Liu, M.; Moriya, S.; Kitahashi, T.; Mahgoub, A.; Mountford, S.J.; Chalmers, D.K.; Soga, T.; Parhar, I.S.; Thompson, P.E. Beta amino acid-modified and fluorescently labelled kisspeptin analogues with potent KISS1R activity. Journal of Peptide Science, 2016, 22(6), 406–414. doi: 10.1002/psc.2883
  4. Zhao, Y.; Fay, F.; Hak, S.; Manuel Perez-Aguilar, J.; Sanchez-Gaytan, B.L.; Goode, B.; Duivenvoorden, R.; de Lange Davies, C.; Bjørkøy, A.; Weinstein, H.; Fayad, Z.A.; Pérez-Medina, C.; Mulder, W.J.M. Augmenting drug-carrier compatibility improves tumour nanotherapy efficacy. Nature Communications, 2016, 7, 11221. doi: 10.1038/ncomms11221
  5. Kwok, S.J.J.; Choi, M.; Bhayana, B.; Zhang, X.; Ran, C.; Yun, S.-H. Two-photon excited photoconversion of cyanine-based dyes. Scientific Reports, 2016, 6, 23866. doi: 10.1038/srep23866
  6. Wang, X.; Wang, C.; Zhang, Q.; Cheng, Y. Near Infrared Light-responsive and Injectable Supramolecular Hydrogels for On-demand Drug Delivery. Chemical Communications, 2016, 52, 978–981. doi: 10.1039/c5cc08391e
  7. Kim, K.S.; Park, W.; Hu, J.; Bae, Y.H.; Na, K. A cancer-recognizable MRI contrast agents using pH-responsive polymeric micelle. Biomaterials, 2014, 35(1), 337-343. doi: 10.1016/j.biomaterials.2013.10.004
  8. Lee, B.-S.; Amano, T.; Wang, H.Q.; Pantoja, J.L.; Yoon, C.W.; Hanson, C.J.; Amatya, R.; Yen, A.; Black, K.L.; Yu, J.S. Reactive Oxygen Species Responsive Nanoprodrug to Treat Intracranial Glioblastoma. ACS Nano, 2013, 7(4), 3061-3077. doi: 10.1021/nn400347j

Cyanine5.5 малеимид

  1. Galstyan, A.; Chiechi, A.; Korman, A.J.; Sun, T.; Isreal, L.L.; Braubach, O.; Patil, R.; Shatalova, E.; Ljubimov, V.A.; Markman, J.; Grodzinski, Z.; Black, K.L.; Penichet, M.L.; Holler, E.; Ljubimov, A.V.; Ding, H.; Ljubimova, J.Y. Nano immunoconjugates crossing blood-brain barrier activate local brain tumor immune system for glioma treatment. bioRxiv. doi: 10.1101/466508
  2. Vishnu Vardhan, G.P.; Hema, M.; Sushmitha, C.; Savithri, H.S.; Natraj, U.; Murthy, M.R.N. Development of sesbania mosaic virus nanoparticles for imaging. Archives of Virology, in press. doi: 10.1007/s00705-018-4097-y
  3. Zhang, C.; Moonshi, S.S.; Wang, W.; Ta, H.T.; Han, Y.; Han, F.Y.; Peng, H.; Král, P.; Rolfe, B.E.; Gooding, J.J.; Gaus, K.; Whittaker, A.K. High F-Content Perfluoropolyether-Based Nanoparticles for Targeted Detection of Breast Cancer by 19F Magnetic Resonance and Optical Imaging. ACS Nano, 2018, 12(9), 9162–9176. doi: 10.1021/acsnano.8b03726
  4. Chung, S.W.; Choi, J.U.; Cho, Y.S.; Kim, H.R.; Won, T.H.; Dimitrion, P.; Jeon, O.-C.; Kim, S.W.; Kim, I.-S.; Kim, S.Y.; Byun, Y. Self-Triggered Apoptosis Enzyme Prodrug Therapy (STAEPT): Enhancing Targeted Therapies via Recurrent Bystander Killing Effect by Exploiting Caspase-Cleavable Linker. Advanced Science, 2018, 5(7), 1800368. doi: 10.1002/advs.201800368
  5. Cai, H.; Wang, X.; Zhang, H.; Sun, L.; Pan, D.; Gong, Q.; Gu, Z.; Luo, K. Enzyme-sensitive biodegradable and multifunctional polymeric conjugate as theranostic nanomedicine. Applied Materials Today, 2018, 11, 207–218. doi: 10.1016/j.apmt.2018.02.003
  6. Matsuoka, D.; Watanabe, H.; Shimizu, Y.; Kimura, H.; Yagi, Y.; Kawai, R.; Ono, M.; Saji, H. Structure–activity relationships of succinimidyl-Cys-C (O)-Glu derivatives with different near-infrared fluorophores as optical imaging probes for prostate-specific membrane antigen. Bioorganic & Medicinal Chemistry, 2018, 26(9), 2291–2301. doi: 10.1016/j.bmc.2018.03.015
  7. Zhang, C.; Moonshi, S.S.; Han, Y.; Puttick, S.; Peng, H.; Magoling, B.J.A.; Reid, J.C.; Bernardi, S.; Searles, D.J.; Král, P.; Whittaker, A.K. PFPE-Based Polymeric 19F MRI Agents: A New Class of Contrast Agents with Outstanding Sensitivity. Macromolecules, 2017, 50(15), 5953–5963. doi: 10.1021/acs.macromol.7b01285
  8. Masarapu, H.; Patel, B.K.; Chariou, P.L.; Hu, H.; Gulati, N.M.; Carpenter, B.L.; Ghiladi, R.A.; Shukla, S.; Steinmetz, N.F. Physalis Mottle Virus-Like Particles as Nanocarriers for Imaging Reagents and Drugs. Biomacromolecules, 2017, 18(12), 4141–4153. doi: 10.1021/acs.biomac.7b01196
  9. Wilks, M.Q.; Normandin, M.D.; Yuan, H.; Cho, H.; Guo, Y.; Herisson, F.; Ayata, C.; Wooten, D.W.; El Fakhri, G.; Josephson, L. Imaging PEG-Like Nanoprobes in Tumor, Transient Ischemia, and Inflammatory Disease Models. Bioconjugate Chemistry, 2015, 26(6), 1061–1069. doi: 10.1021/acs.bioconjchem.5b00213
  10. Cai, H.; Singh, A.N.; Sun, X.; Peng, F. Synthesis and Characterization of Her2-NLP Peptide Conjugates Targeting Circulating Breast Cancer Cells: Cellular Uptake and Localization by Fluorescent Microscopic Imaging. Journal of Fluorescence, 2015, 25(1), 113–117. doi: 10.1007/s10895-014-1486-9
  11. Graen, T.M.D.; Hoefling, M.; Grubmüller, H. AMBER-DYES: Characterization of Charge Fluctuations and Force Field Parameterization of Fluorescent Dyes for Molecular Dynamics Simulations. Journal of Chemical Theory and Computation, 2014, 10(12), 5505-5512. doi: 10.1021/ct500869p
  12. Park, S.; Kim, Y.-J.; Jon, S. A high-affinity peptide for nicotinic acetylcholine receptor-α1 and its potential use in pulmonary drug delivery. Journal of Controlled Release, 2014, 192, 141-147. doi: 10.1016/j.jconrel.2014.07.006
  13. Wang, X.; Yang, Y.; Jia, H.; Jia, W.; Miller, S.; Bowman, B.; Feng, J.; Zhan, F. Peptide decoration of nanovehicles to achieve active targeting and pathology-responsive cellular uptake for bone metastasis chemotherapy. Biomaterials Science, 2014, 2(7), 961-971. doi: 10.1039/c4bm00020j
  14. Fan, H.; Zhang, I.; Chen, X.; Zhang, L.; Wang, H.; Da Fonseca, A.; Manuel, E.R.; Diamond, D.J.; Raubitschek, A.; Badie, B. Intracerebral CpG Immunotherapy with Carbon Nanotubes Abrogates Growth of Subcutaneous Melanomas in Mice. Clinical Cancer Research, 2012, 18(20), 5628-5638. doi: 10.1158/1078-0432.ccr-12-1911
  15. Zhao, D.; Alizadeh, D.; Zhang, L.; Liu, W.; Farrukh, O.; Manuel, E.; Diamond, D.J.; Badie, B. Carbon Nanotubes Enhance CpG Uptake and Potentiate Antiglioma Immunity. Clinical Cancer Research, 2011, 17(4), 771–782. doi: 10.1158/1078-0432.ccr-10-2444

Cyanine7 азид

  1. Meka, R.R.; Venkatesha, S.H.; Moudgil, K.D. Peptide-directed liposomal delivery improves the therapeutic index of an immunomodulatory cytokine in controlling autoimmune arthritis. Journal of Controlled Release, 2018, 286, 279–288. doi: 10.1016/j.jconrel.2018.08.007
  2. Lyu, Z.; Kang, L.; Buuh, Z.Y.; Jiang, D.; McGuth, J.C.; Du, J.; Wissler, H.L.; Cai, W.; Wang, R.E. A Switchable Site-Specific Antibody Conjugate. ACS Chemical Biology, 2018, 13(4), 958–964. doi: 10.1021/acschembio.8b00107
  3. Maudens, P.; Seemayer, C.A.; Thauvin, C.; Gabay, C.; Jordan, O.; Allémann, E. Nanocrystal-Polymer Particles: Extended Delivery Carriers for Osteoarthritis Treatment. Small, 2018, 14(8), 1703108. doi: 10.1002/smll.201703108
  4. Morton, S.W.; Zhao, X.; Quadir, M.A.; Hammond, P.T. FRET-enabled biological characterization of polymeric micelles. Biomaterials, 2014, 35(11), 3489-3496. doi: 10.1016/j.biomaterials.2014.01.027

Cyanine7 активированный эфир

  1. Smith, W.J.; Wang, G.; Gaikwad, H.; Vu, V.P.; Groman, E.; Bourne, D.W.A.; Simberg, D. Accelerated Blood Clearance of Antibodies by Nanosized Click Antidotes. ACS Nano, 2018, 12(12), 12523–12532. doi: 10.1021/acsnano.8b07003
  2. Li, W.; Li, Y.; Liu, Z.; Kerdsakundee, N.; Zhang, M.; Zhang, F.; Liu, X.; Bauleth-Ramos, T.; Lian, W.; Mäkilä, E.; Kemell, M.; Ding, Y.; Sarmento, B.; Wiwattanapatapee, R.; Salonen, J.; Zhang, H.; Hirvonen, J.T.; Liu, D.; Deng, X.; Santos, H.A. Hierarchical structured and programmed vehicles deliver drugs locally to inflamed sites of intestine. Biomaterials, 2018, 185, 322–332. doi: 10.1016/j.biomaterials.2018.09.024
  3. Besford, Q.A.; Ju, Y.; Wang, T.-Y.; Yun, G.; Cherepanov, P.V.; Hagemeyer, C.E.; Cavalieri, F.; Caruso, F. Self-Assembled Metal-Phenolic Networks on Emulsions as Low-Fouling and pH-Responsive Particles. Small, 2018, 14(39), e1802342. doi: 10.1002/smll.201802342
  4. Etrych, T.; Daumová, L.; Pokorná, E.; Tušková, D.; Lidický, O.; Kolářová, V.; Pankrác, J.; Šefc, L.; Chytil, P.; Klener, P. Effective doxorubicin-based nano-therapeutics for simultaneous malignant lymphoma treatment and lymphoma growth imaging. Journal of Controlled Release, 2018, 289, 44–55. doi: 10.1016/j.jconrel.2018.09.018
  5. Bonnard, T.; Jayapadman, A.; Putri, J.A.; Cui, J.; Ju, Y.; Carmichael, C.; Angelovich, T.A.; Cody, S.H.; French, S.; Pascaud, K.; Pearce, H.A.; Jagdale, S.; Caruso, F.; Hagemeyer, C.E. Low-Fouling and Biodegradable Protein-Based Particles for Thrombus Imaging. ACS Nano, 2018, 12(7), 6988–6996. doi: 10.1021/acsnano.8b02588
  6. Moroz, P.; Jin, Z.; Sugiyama, Y.; Lara, D'A.; Razgoniaeva, N.; Yang, M.; Kholmicheva, N.; Khon, D.; Mattoussi, H.; Zamkov, M. The Competition of Charge and Energy Transfer Processes in Donor-Acceptor Fluorescence Pairs: Calibrating the Spectroscopic Ruler. ACS Nano, 2018, 12(6), 5657–5665. doi: 10.1021/acsnano.8b01451
  7. Gusliakova, O.; Atochina-Vasserman, E.N.; Sindeeva, O.; Sindeev, S.; Pinyaev, S.; Pyataev, N.; Revin, V.; Sukhorukov, G.B.; Gorin, D.; Gow, A.J. Use of Submicron Vaterite Particles Serves as an Effective Delivery Vehicle to the Respiratory Portion of the Lung. Frontiers in Pharmacology, 2018, 9, 559. doi: 10.3389/fphar.2018.00559
  8. Ashwanikumar, N.; Plaut, J.S.; Mostofian, B.; Patel, S.; Kwak, P.; Sun, C.; McPhail, K.; Zuckerman, D.M.; Esener, S.C.; Sahay, G. Supramolecular self assembly of nanodrill-like structures for intracellular delivery. Journal of Controlled Release, 2018, 282, 76–89. doi: 10.1016/j.jconrel.2018.02.041
  9. Zhang, X.; He, F.; Xiang, K.; Zhang, J.; Xu, M.; Long, P.; Su, H.; Gan, Z.; Yu, Q. CD44-targeted Facile Enzymatic Activatable Chitosan Nanoparticles for Efficient Antitumor Therapy and Reversal of Multidrug Resistance. Biomacromolecules, 2018, 19(3), 883–895. doi: 10.1021/acs.biomac.7b01676
  10. Tal, N.; Rudnick-Glick, S.; Grinberg, I.; Natan, M.; Banin, E.; Margel, S. Engineering of a New Bisphosphonate Monomer and Nanoparticles of Narrow Size Distribution for Antibacterial Applications. ACS Omega, 2018, 3(2), 1458–1469. doi: 10.1021/acsomega.7b01686
  11. Newman, M.R.; Russell, S.G.; Schmitt, C.S.; Marozas, I.A.; Sheu, T.-J.; Puzas, J.E.; Benoit, D.S.W. Multivalent Presentation of Peptide Targeting Groups Alters Polymer Biodistribution to Target Tissues. Biomacromolecules, 2018, 19(1), 71–84. doi: 10.1021/acs.biomac.7b01193
  12. Suleimanov, I.; Gabor, M.; Lionel, S.; Bousseksou, A. Near-infrared luminescence switching in a spin-crossover polymer nanocomposite. European Journal of Inorganic Chemistry, 2017, 28, 3446–3451. doi: 10.1002/ejic.201700426
  13. Wang, Y.; Malcolm, D.W.; Benoit, D.S.W. Controlled and sustained delivery of siRNA/NPs from hydrogels expedites bone fracture healing. Biomaterials, 2017, 139, 127–138. doi: 10.1016/j.biomaterials.2017.06.001
  14. Zhang, R.; Yang, J.; Radford, D.C.; Fang, Y.; Kopeček, J. FRET Imaging of Enzyme-Responsive HPMA Copolymer Conjugate. Macromolecular Bioscience, 2017, 17(1), 1600125. doi: 10.1002/mabi.201600125
  15. Shen, T.; Xu, X.; Guo, L.; Tang, H.; Diao, T.; Gan, Z.; Zhang, G.; Yu, Q. Efficient Tumor Accumulation, Penetration and Tumor Growth Inhibition Achieved by Polymer Therapeutics: The Effect of Polymer Architectures. Biomacromolecules, 2017, 18(1), 217–230. doi: 10.1021/acs.biomac.6b01533
  16. Kilic, E.; Novoselova, M.V.; Lim, S.H.; Pyataev, N.A.; Pinyaev, S.I.; Kulikov, O.A.; Sindeeva, O.A.; Mayorova, O.A.; Murney, R.; Antipina, M.N.; Haigh, B.; Sukhorukov, G.B.; Kiryukhin, M.V. Formulation for Oral Delivery of Lactoferrin Based on Bovine Serum Albumin and Tannic Acid Multilayer Microcapsules. Scientific Reports, 2017, 7, 44159. doi: 10.1038/srep44159
  17. Beldman, T.J.; Senders, M.L.; Alaarg, A.; Perez-Medina, C.; Tang, J.; Zhao, Y.; Fay, F.; Deichmöller, J.; Born, B.; Desclos, E.; van der Wel, N.N.; Hoebe, R.A.; Kohen, F.; Kartvelishvily, E.; Neeman, M.; Reiner, T.; Calcagno, C.; Fayad, Z.A.; de Winther, M.P.J.; Lutgens, E.; Mulder, W.J.M.; Kluza, E. Hyaluronan Nanoparticles Selectively Target Plaque-Associated Macrophages and Improve Plaque Stability in Atherosclerosis. ACS Nano, 2017, 11(6), 5785–5799. doi: 10.1021/acsnano.7b01385
  18. Rudnick-Glick, S.; Corem-Salkmon, E.; Grinberg, I.; Margel, S. Targeted drug delivery of near IR fluorescent doxorubicin-conjugated poly(ethylene glycol) bisphosphonate nanoparticles for diagnosis and therapy of primary and metastatic bone cancer in a mouse model. Journal of Nanobiotechnology, 2016, 14, 80. doi: 10.1186/s12951-016-0233-6
  19. Xu, X.; Xu, Z.; Liu, J.; Zhang, Z.; Chen, H.; Li, X.; Shi, S. Visual tracing of diffusion and biodistribution for amphiphilic cationic nanoparticles using photoacoustic imaging after ex vivo intravitreal injections. International Journal of Nanomedicine, 2016, 11, 5079–5086. doi: 10.2147/IJN.S109986
  20. Gera, L.; Charest-Morin, X.; Jean, M.; Bachelard, H.; Marceau, F. Infrared-emitting, peptidase-resistant fluorescent ligands of the bradykinin B2 receptor: application to cytofluorometry and imaging. BMC Research Notes, 2016, 9, 452. doi: 10.1186/s13104-016-2258-1
  21. Zhao, L.; Ma, S.; Pan, Y.; Zhang, Q.; Wang, K.; Song, D.; Wang, X.; Feng, G.; Liu, R.; Xu, H.; Zhang, J.; Qiao, M.; Kong, D. Functional Modification of Fibrous PCL Scaffolds with Fusion Protein VEGF-HGFI Enhanced Cellularization and Vascularization. Advanced Healthcare Materials, 2016, 5(18), 2376–2385. doi: 10.1002/adhm.201600226
  22. Sui, B.; Zhong, G.; Sun, J. Drug-loadable Mesoporous Bioactive Glass Nanospheres: Biodistribution, Clearance, BRL Cellular Location and Systemic Risk Assessment via 45Ca Labelling and Histological Analysis. Scientific Reports, 2016, 6, 33443. doi: 10.1038/srep33443
  23. Su, S.; Wang, J.; Vargas, E.; Wei, J.; Martinez-Zaguilan, R.; Sennoune, S.R.; Pantoya, M.L.; Wang, S.; Chaudhuri, J.; Qiu, J. Porphyrin Immobilized Nano-Graphene Oxide for Enhanced and Targeted Photothermal Therapy of Brain Cancer. ACS Biomaterials Science & Engineering, 2016, 2(8), 1357–1366. doi: 10.1021/acsbiomaterials.6b00290
  24. Zhang, L.; Navaratna, T.; Thurber, G.M. A Helix-Stabilizing Linker Improves Subcutaneous Bioavailability of a Helical Peptide Independent of Linker Lipophilicity , 2016, 27(7), 1663–1672. doi: 10.1021/acs.bioconjchem.6b00209
  25. Pérez-Medina, C.; Abdel-Atti, D.; Tang, J.; Zhao, Y.; Fayad, Z.A.; Lewis, J.S.; Mulder, W.J.M.; Reiner, T. Nanoreporter PET predicts the efficacy of anti-cancer nanotherapy. Nature Communications, 2016, 7, 11838. doi: 10.1038/ncomms11838
  26. Zhao, Y.; Fay, F.; Hak, S.; Manuel Perez-Aguilar, J.; Sanchez-Gaytan, B.L.; Goode, B.; Duivenvoorden, R.; de Lange Davies, C.; Bjørkøy, A.; Weinstein, H.; Fayad, Z.A.; Pérez-Medina, C.; Mulder, W.J.M. Augmenting drug-carrier compatibility improves tumour nanotherapy efficacy. Nature Communications, 2016, 7, 11221. doi: 10.1038/ncomms11221
  27. Dhande, Y.K.; Wagh, B.S.; Hall, B.C.; Sprouse, D.; Hackett, P.B.; Reineke, T.M. N-Acetylgalactosamine Block-co-Polycations Form Stable Polyplexes with Plasmids and Promote Liver-Targeted Delivery. Biomacromolecules, 2016, 17(3), 830–840. doi: 10.1021/acs.biomac.5b01555
  28. Kim, J.B.; Park, K.; Ryu, Ji.; Lee, J.J.; Lee, M.W.; Cho, H.S.; Nam, H.S.; Park, O.K.; Song, J.W.; Kim, T.S.; Oh, D.J.; Gweon, D.; Oh, W.-Y.; Yoo, H.; Kim, J.W. Intravascular optical imaging of high-risk plaques in vivo by targeting macrophage mannose receptors. Scientific Reports, 2016, 6, 22608. doi: 10.1038/srep22608
  29. Tolstyka, Z.P.; Phillips, H.; Cortez, M.; Wu, Y.; Ingle, N.; Bell, J.B.; Hackett, P.B.; Reineke, T.M. Trehalose-Based Block Copolycations Promote Polyplex Stabilization for Lyophilization and in Vivo pDNA Delivery. ACS Biomaterials Science & Engineering, 2016, 2(1), 43–55. doi: 10.1021/acsbiomaterials.5b00312
  30. Turcheniuk, K.; Dumych, T.; Bilyy, R.; Turcheniuk, V.; Bouckaert, J.; Vovk, V.; Chopyak, V.; Zaitsev, V.; Mariot, P.; Prevarskaya, N.; Boukherrouba, R.; Szunerits, S. Plasmonic photothermal cancer therapy with gold nanorods/reduced graphene oxide core/shell nanocomposites. RSC Advances, 2016, 6(2), 1600–1610. doi: 10.1039/c5ra24662h
  31. Gremse, F.; Doleschel, D.; Zafarnia, S.; Babler, A.; Jahnen-Dechent, W.; Lammers, T.; Lederle, W.; Kiessling, F. Hybrid µCT-FMT imaging and image analysis. Journal of Visualized Experiments, 2015, e52770. doi: 10.3791/52770
  32. Rudnick-Glick, S.; Corem-Salkmon, E.; Grinberg, I.; Yehuda, R.; Margel, S. Near IR fluorescent conjugated poly(ethylene glycol)bisphosphonate nanoparticles for in vivo bone targeting in a young mouse model. Journal of Nanobiotechnology, 2015, 13(1), 80. doi: 10.1186/s12951-015-0126-0
  33. Alexander, S.C.; Busby, K.N.; Cole, C.M.; Zhou, C.Y.; Devaraj, N.K. Site-Specific Covalent Labeling of RNA by Enzymatic Transglycosylation. Journal of the American Chemical Society, 2015, 137(40), 12756–12759. doi: 10.1021/jacs.5b07286
  34. Yu, Q.; Wei, Z.; Shi, J.; Guan, S.; Du, N.; Shen, T.; Tang, H.; Jia, B.; Wang, F.; Gan, Z. Polymer-Doxorubicin Conjugate Micelles Based on Poly(ethylene glycol) and Poly(N-(2-hydroxypropyl) methacrylamide): Effect of Negative Charge and Molecular Weight on Biodistribution and Blood Clearance. Biomacromolecules, 2015, 16(9), 2645–2655. doi: 10.1021/acs.biomac.5b00460
  35. Mwangi, T.K.; Bowles, R.D.; Tainter, D.M.; Bell, R.D.; Kaplan, D.L.; Setton, L.A. Synthesis and characterization of silk fibroin microparticles for intra-articular drug delivery. International Journal of Pharmaceutics, 2015, 485(1–2), 7–14. doi: 10.1016/j.ijpharm.2015.02.059
  36. Shi, Y.; van der Meel, R.; Theek, B.; Oude Blenke, E.; Pieters, E.H.E.; Fens, M.H.A.M.; Ehling, J.; Schiffelers, R.M.; Storm, G.; van Nostrum, C.F.; Lammers, T.; Hennink, W.E. Complete Regression of Xenograft Tumors upon Targeted Delivery of Paclitaxel via Π–Π Stacking Stabilized Polymeric Micelles. ACS Nano, 2015, 9(4), 3740–3752. doi: 10.1021/acsnano.5b00929
  37. Zhang, J.; Wang, G.; Mao, D.; Han, A.; Xiao, N.; Qi, X.; Ding, D.; Kong, D. Targeted In Vivo Imaging of Mouse Hindlimb Ischemia Using Fluorescent Gelatin Nanoparticles. Journal of Nanomaterials, 2015, 2015, Article ID 704817
  38. Choi, E.B.; Choi, J.; Bae, S.R.; Kim, H.-O.; Jang, E.; Kang, B.; Kim, M.-H.; Kim, B.; Suh, J.-S.; Lee, K. et al. Colourimetric redox-polyaniline nanoindicator for in situ vesicular trafficking of intracellular transport. Nano Research, 2015, 8(4), 1169–1179. doi: 10.1007/s12274-014-0597-6
  39. Brady, M.L.; Raghavan, R.; Singh, D.; Anand, P.; Fleisher, A.S.; Mata, J.; Broaddus, W.C.; Olbricht, W.L. In vivo performance of a microfabricated catheter for intraparenchymal delivery. Journal of Neuroscience Methods, 2014, 229, 76-83. doi: 10.1016/j.jneumeth.2014.03.016
  40. Graen, T.M.D.; Hoefling, M.; Grubmüller, H. AMBER-DYES: Characterization of Charge Fluctuations and Force Field Parameterization of Fluorescent Dyes for Molecular Dynamics Simulations. Journal of Chemical Theory and Computation, 2014, 10(12), 5505-5512. doi: 10.1021/ct500869p
  41. Lin, X.; Zhu, H.; Luo, Z.; Hong, Y.; Zhang, H.; Liu, X.; Ding, H.; Tian, H.; Yang, Z. Near-Infrared Fluorescence Imaging of Non-Hodgkin's Lymphoma CD20 Expression Using Cy7-Conjugated Obinutuzumab. Molecular Imaging and Biology, 2014. doi: 10.1007/s11307-014-0742-3
  42. Novo, L.; Rizzo, L.Y.; Golombek, S.K.; Dakwar, G.R.; Lou, B.; Remaut, K.; Mastrobattista, E.; van Nostrum, C.F.; Jahnen-Dechent, W.; Kiessling, F. et al. Decationized polyplexes as stable and safe carrier systems for improved biodistribution in systemic gene therapy. Journal of Controlled Release, 2014, 195, 162-175. doi: 10.1016/j.jconrel.2014.08.028
  43. Zhao, Y.; Meek, G.A.; Levine, B.G.; Lunt, R.R. Near-Infrared Harvesting Transparent Luminescent Solar Concentrators. Advanced Optical Materials, 2014, 2(7), 606-611. doi: 10.1002/adom.201400103
  44. Skaat, H.; Corem-Salkmon, E.; Grinberg, I.; Last, D.; Goez, D.; Mardor, Y.; Margel, S. Antibody-conjugated, dual-modal, near-infrared fluorescent iron oxide nanoparticles for antiamyloidgenic activity and specific detection of amyloid-β fibrils. International Journal of Nanomedicine, 2013, 8, 4063–4076. doi: 10.2147/ijn.s52833
  45. Gluz, E.; Grinberg, I.; Corem-Salkmon, E.; Mizrahi, D.; Margel, S. Engineering of new crosslinked near-infrared fluorescent polyethylene glycol bisphosphonate nanoparticles for bone targeting. Journal of Polymer Science, Part A: Polymer Chemistry, 2013, 51(20), 4282-4291. doi: 10.1002/pola.26858
  46. Gluz, E.; Mizrahi, D.M.; Margel, S. Synthesis and characterization of new poly(ethylene glycol)bisphosphonate vinylic monomer and non-fluorescent and NIR-fluorescent bisphosphonate micrometer-sized particles. Polymer, 2013, 54(2), 565-571. doi: 10.1016/j.polymer.2012.11.071
  47. Saxena, T.; Karumbaiah, L.; Gaupp, E.A.; Patkar, R.; Patil, K.; Betancur, M.; Stanley, G.B.; Bellamkonda, R.V. The impact of chronic blood-brain barrier breach on intracortical electrode function. Biomaterials, 2013, 34(20), 4703-4713. doi: 10.1016/j.biomaterials.2013.03.007

Cyanine7 алкин

  1. Tang, H.; Zhang, J.; Tang, J.; Shen, Y.; Guo, W.; Zhou, M.; Wang, R.; Jiang, N.; Gan, Z.; Yu, Q. Tumor specific and renal excretable star-like tri-block polymer-doxorubicin conjugates for safe and efficient anticancer therapy. Biomacromolecules, 2018, 19(7), 2849–2862. doi: 10.1021/acs.biomac.8b00425
  2. Smith, A.A.A.; Zuwala, K.; Pilgram, O.; Johansen, K.S.; Tolstrup, M.; Dagnæs-Hansen, F.; Zelikin, A.N. Albumin-Polymer-Drug Conjugates: Long Circulating, High Payload Drug Delivery Vehicles. ACS Macro Letters, 2016, 5, 1089–1094. doi: 10.1021/acsmacrolett.6b00544
  3. Zhang, L.; Thurber, G.M. Quantitative Impact of Plasma Clearance and Down-regulation on GLP-1 Receptor Molecular Imaging. Molecular Imaging and Biology, 2016, 18(1), 79–89. doi: 10.1007/s11307-015-0880-2

Cyanine7 амин

  1. Nuhn, L.; De Koker, S.; Van Lint, S.; Zhong, Z.; Catani, J.P.; Combes, F.; Deswarte, K.; Li, Y.; Lambrecht, B.N.; Lienenklaus, S.; Sanders, N.N.; David, S.A.; Tavernier, J.; De Geest, B.G. Nanoparticle-Conjugate TLR7/8 Agonist Localized Immunotherapy Provokes Safe Antitumoral Responses. Advanced Materials, 2018, 30(45), e1803397. doi: 10.1002/adma.201803397
  2. Joo, J.; Poon, C.; Yoo, S.P.; Chung, E.J. Shape Effects of Peptide Amphiphile Micelles for Targeting Monocytes. Molecules, 2018, 23(11), 2786. doi: 10.3390/molecules23112786
  3. Melgar-Asensio, I.; Kandela, I.; Aird, F.; Darjatmoko, S.R.; de Los Rios, C.; Sorenson, C.M.; Albert, D.M.; Sheibani, N.; Henkin, J. Extended Intravitreal Rabbit Eye Residence of Nanoparticles Conjugated With Cationic Arginine Peptides for Intraocular Drug Delivery: In Vivo Imaging. Investigative Ophthalmology & Visual Science, 2018, 59(10), 4071–4081. doi: 10.1167/iovs.18-24087
  4. Segura-Ibarra, V.; Cara, F.E.; Wu, S.; Iruegas-Nunez, D.A.; Wang, S.; Ferrari, M.; Ziemys, A.; Valderrabano, M.; Blanco, E. Nanoparticles administered intrapericardially enhance payload myocardial distribution and retention. Journal of Controlled Release, 2017, 262, 18–27. doi: 10.1016/j.jconrel.2017.07.012
  5. Cheng, L.; Ji, K.; Shih, T. Y.; Haddad, A.; Giatsidis, G.; Mooney, D.J.; Orgill, D.P.; Nabzdyk, C.S. Injectable Shape-Memorizing Three-Dimensional Hyaluronic Acid Cryogels for Skin Sculpting and Soft Tissue Reconstruction. Tissue Engineering Part A, 2017, 23(5–6), 243–251. doi: 10.1089/ten.tea.2016.0263

Cyanine7 карбоновая кислота

  1. Luthman, A.S. Wide-Field fHSI with a Linescan SRDA. In: Spectrally Resolved Detector Arrays for Multiplexed Biomedical Fluorescence Imaging (Springer Thesis), 2018, 51–85. doi: 10.1007/978-3-319-98255-7_3
  2. Luthman, A.S.; Dumitru, S.; Quiros-Gonzalez, I.; Joseph, J.; Bohndiek, S.E. Fluorescence hyperspectral imaging (fHSI) using a spectrally resolved detector array. Journal of Biophotonics, 2017, 10(6–7), 840–853. doi: 10.1002/jbio.201600304
  3. Zhao, Y.; Fay, F.; Hak, S.; Manuel Perez-Aguilar, J.; Sanchez-Gaytan, B.L.; Goode, B.; Duivenvoorden, R.; de Lange Davies, C.; Bjørkøy, A.; Weinstein, H.; Fayad, Z.A.; Pérez-Medina, C.; Mulder, W.J.M. Augmenting drug-carrier compatibility improves tumour nanotherapy efficacy. Nature Communications, 2016, 7, 11221. doi: 10.1038/ncomms11221
  4. Ma, X.; Cheng, Z.; Jin, Y.; Liang, X.; Yang, X.; Dai, Z.; Tian, J. SM5-1-Conjugated PLA nanoparticles loaded with 5-fluorouracil for targeted hepatocellular carcinoma imaging and therapy. Biomaterials, 2014, 35(9), 2878-2889. doi: 10.1016/j.biomaterials.2013.12.045

Cyanine7 малеимид

  1. Melgar-Asensio, I.; Kandela, I.; Aird, F.; Darjatmoko, S.R.; de Los Rios, C.; Sorenson, C.M.; Albert, D.M.; Sheibani, N.; Henkin, J. Extended Intravitreal Rabbit Eye Residence of Nanoparticles Conjugated With Cationic Arginine Peptides for Intraocular Drug Delivery: In Vivo Imaging. Investigative Ophthalmology & Visual Science, 2018, 59(10), 4071–4081. doi: 10.1167/iovs.18-24087
  2. Matsuoka, D.; Watanabe, H.; Shimizu, Y.; Kimura, H.; Yagi, Y.; Kawai, R.; Ono, M.; Saji, H. Structure–activity relationships of succinimidyl-Cys-C (O)-Glu derivatives with different near-infrared fluorophores as optical imaging probes for prostate-specific membrane antigen. Bioorganic & Medicinal Chemistry, 2018, 26(9), 2291–2301. doi: 10.1016/j.bmc.2018.03.015
  3. Tondera, C.; Wieduwild, R.; Röder, E.; Werner, C.; Zhang, Y.; Pietzsch, J. In Vivo Examination of an Injectable Hydrogel System Crosslinked by Peptide-Oligosaccharide Interaction in Immunocompetent Nude Mice. In Vivo Examination of an Injectable Hydrogel System Crosslinked by Peptide-Oligosaccharide Interaction in Immunocompetent Nude Mice, 2017, 27(15), 1605189. doi: 10.1002/adfm.201605189
  4. Wang, T.; Tang, Y.; He, X.; Yan, J.; Wang, C.; Feng, X. Self-Assembled Raspberry-Like Core/Satellite Nanoparticles for Anti-Inflammatory Protein Delivery. ACS Applied Materials & Interfaces, 2017, 9(8), 6902–6907. doi: 10.1021/acsami.6b16277
  5. Schwarz, B.; Madden, P.; Avera, J.; Gordon, B.; Larson, K.; Miettinen, H.; Uchida, M.; LaFrance, B.; Basu, G.; Rynda-Apple, A.; Douglas, T. Symmetry Controlled, Genetic Presentation of Bio-Active Proteins on the P22 Virus-Like Particle Using an External Decoration Protein. ACS Nano, 2015, 9(9), 9134–9147. doi: 10.1021/acsnano.5b03360

Cyanine7.5 азид

  1. Kong, J.-N.; Zhu, Z.; Itokazu, Y.; Wang, G.; Dinkins, M.B.; Zhong, L.; Lin, H.-P.; Elsherbini, A.; Leanhart, S.; Jiang, X.; Qin, H.; Zhi, W.; Spassieva, S.D.; Bieberich, E. Novel function of ceramide for regulation of mitochondrial ATP release in astrocytes. Journal of Lipid Research, 2018, 59(3), 488–506. doi: 10.1194/jlr.M081877
  2. van der Steen, S.C.H.A.; Raavé, R.; Langerak, S.; van Houdt, L.; van Duijnhoven, S.M.J.; van Lith, S.A.M.; Massuger, L.F.A.G.; Daamen, W.F.; Leenders, W.P.; van Kuppevelt, T.H. Targeting the extracellular matrix of ovarian cancer using functionalized, drug loaded lyophilisomes. European Journal of Pharmaceutics and Biopharmaceutics, 2017, 113, 229–239. doi: 10.1016/j.ejpb.2016.12.010
  3. Junker, M.; Rapoport, T.A. Involvement of VAT-1 in phosphatidylserine transfer from the endoplasmic reticulum to mitochondria. Traffic, 2015, 16(12), 1306–1317. doi: 10.1111/tra.12336

Cyanine7.5 активированный эфир

  1. Näkki, S.; Wang, J.T.-W.; Wu, J.; Fan, L.; Rantanen, J.; Nissinen, T.; Kettunen, M.I.; Backholm, M.; Ras, R.H.A.; Al-Jamal, K.T.; Lehto, V.-P.; Xu, W. Designed inorganic porous nanovector with controlled release and MRI features for safe administration of doxorubicin. International Journal of Pharmaceutics, 2019, 554, 327–336. doi: 10.1016/j.ijpharm.2018.10.074
  2. Xu, H.; Bandari, R.; Lee, L.E.; Li, R.; Yu, P.; Smith, C.J.; Ma, L. Design, Synthesis, and In Vitro and In Vivo Evaluation of High Affinity and Specificity Near-Infrared Fluorescent Bombesin Antagonists for Tumor Imaging. Journal of Medicinal Chemistry, 2018, 61(17), 7657–7670. doi: 10.1021/acs.jmedchem.8b00614
  3. Jones, J.E.; Busi, S.B.; Mitchem, J.B.; Amos-Landgraf, J.M.; Lewis, M.R. Evaluation of a Tumor-Targeting, Near-Infrared Fluorescent Peptide for Early Detection and Endoscopic Resection of Polyps in a Rat Model of Colorectal Cancer. Molecular Imaging, 2018, 17, 1536012118790065. doi: 10.1177/1536012118790065
  4. He, S.; Li, C.; Zhang, Q.; Ding, J.; Liang, X.-J.; Chen, X.; Xiao, H.; Chen, X.; Zhou, D.; Huang, Y. Tailoring Platinum(IV) Amphiphiles for Self-Targeting All-in-One Assemblies as Precise Multimodal Theranostic Nanomedicine. ACS Nano, 2018, 12(7), 7272–7281. doi: 10.1021/acsnano.8b03476
  5. Xue, F.; Wang, Y.; Zhang, Q.; Han, S.; Zhang, F.; Jin, T.; Li, C.; Hu, H.; Zhang, J. Self-assembly of affinity-controlled nanoparticles via host-guest interactions for drug delivery. Nanoscale, 2018, 10(26), 12364–12377. doi: 10.1039/C8NR01518J
  6. Li, H.; Li, K.; Dai, Y.; Xu, X.; Cao, X.; Zeng, Q.; He, H.; Pang, L.; Liang, J.; Chen, X.; Zhan, Y. In vivo near infrared fluorescence imaging and dynamic quantification of pancreatic metastatic tumors using folic acid conjugated biodegradable mesoporous silica nanoparticles. Nanomedicine: Nanotechnology, Biology and Medicine, 2018, 14(6), 1867–1877. doi: 10.1016/j.nano.2018.04.018
  7. Malhotra, M.; Sekar, T.V.; Ananta, J.S.; Devulapally, R.; Afjei, R.; Babikir, H.A.; Paulmurugan, R.; Massoud, T.F. Targeted nanoparticle delivery of therapeutic antisense microRNAs presensitizes glioblastoma cells to lower effective doses of temozolomide in vitro and in a mouse model. Oncotarget, 2018, 9(30), 21478–21494. doi: 10.18632/oncotarget.25135
  8. Shi, F.; Li, M.; Wang, J.; Wu, D.; Pan, M.; Guo, M.; Dou, J. Induction of multiple myeloma cancer stem cell apoptosis using conjugated anti-ABCG2 antibody with epirubicin-loaded microbubbles. Stem Cell Research & Therapy, 2018, 9, 144. doi: 10.1186/s13287-018-0885-2
  9. Loebel, C.; Rodell, C.B.; Chen, M.H.; Burdick, J.A. Shear-thinning and self-healing hydrogels as injectable therapeutics and for 3D-printing. Nature Protocols, 2017, 12(8), 1521–1541. doi: 10.1038/nprot.2017.053
  10. O'Mary, H.L.; Aldayel, A.M.; Valdes, S.A.; Naguib, Y.W.; Li, X.; Salvady, K.; Cui, Z. Acid-sensitive sheddable PEGylated, mannose-modified nanoparticles increase the delivery of betamethasone to chronic inflammation sites in a mouse model. Molecular Pharmaceutics, 2017, 14(6), 1929–1937. doi: 10.1021/acs.molpharmaceut.7b00024
  11. Sivak, L.; Subr, V.; Tomala, J.; Rihova, B.; Strohalm, J.; Etrych, T.; Kovar, M. Overcoming multidrug resistance via simultaneous delivery of cytostatic drug and P-glycoprotein inhibitor to cancer cells by HPMA copolymer conjugate. Biomaterials, 2017, 115, 65–80. doi: 10.1016/j.biomaterials.2016.11.013
  12. Lin, S.; Shah, A.; Hernández-Gil, J.; Stanziola, A.; Harriss, B.I.; Matsunaga, T.O.; Long, N.; Bamber, J.; Tang, M.-X. Optically and acoustically triggerable sub-micron phase-change contrast agents for enhanced photoacoustic and ultrasound imaging. Photoacoustics, 2017, 6, 26–36. doi: 10.1016/j.pacs.2017.04.001
  13. Cheng, J.; Feng, S.; Han, S.; Zhang, X.; Chen, Y.; Zhou, X.; Wang, R.; Li, X.; Hu, H.; Zhang, J. Facile Assembly of Cost-Effective and Locally Applicable or Injectable Nanohemostats for Hemorrhage Control. ACS Nano, 2016, 10(11), 9957&ndash9973. doi: 10.1021/acsnano.6b04124
  14. Zhang, Q.; Tao, H.; Lin, Y.; Hu, Y.; An, H.; Zhang, D.; Feng, S.; Hu, H.; Wang, R.; Li, X.; Zhang, J. A superoxide dismutase/catalase mimetic nanomedicine for targeted therapy of inflammatory bowel disease. Biomaterials, 2016, 105, 206–221. doi: 10.1016/j.biomaterials.2016.08.010
  15. Feng, S.; Hu, Y.; Peng, S.; Han, S.; Tao, H.; Zhang, Q.; Xu, X.; Zhang, J.; Hu, H. Nanoparticles responsive to the inflammatory microenvironment for targeted treatment of arterial restenosis. Biomaterials, 2016, 105, 167–184. doi: 10.1016/j.biomaterials.2016.08.003
  16. Dou, Y.; Guo, J.; Chen, Y.; Han, S.; Xu, X.; Shi, Q.; Jia, Y.; Liu, Y.; Deng, Y.; Wang, R.; Li, X.; Zhang, J. Sustained delivery by a cyclodextrin material-based nanocarrier potentiates antiatherosclerotic activity of rapamycin via selectively inhibiting mTORC1 in mice. Journal of Controlled Release, 2016, 235, 48–62. doi: 10.1016/j.jconrel.2016.05.049
  17. Markovic, S.; Belz, J.; Kumar, R.; Cormack, R.A.; Sridhar, S.; Niedre, M. Near-infrared fluorescence imaging platform for quantifying in vivo nanoparticle diffusion from drug loaded implants. International Journal of Nanomedicine, 2016, 11, 1213–1223. doi: 10.2147/IJN.S93324
  18. Zhang, Z.; Cai, H.; Liu, Z.; Yao, P. Effective Enhancement of Hypoglycemic Effect of Insulin by Liver-targeted Nanoparticles Containing Cholic Acid-modified Chitosan Derivative. Molecular Pharmaceutics, 2016, 13(7), 2433–2442. doi: 10.1021/acs.molpharmaceut.6b00188
  19. Han, F.Y.; Thurecht, K.J.; Lam, A.-L.; Whittaker, A.K.; Smith, M.T. Novel Polymeric Bioerodable Microparticles for Prolonged-Release Intrathecal Delivery of Analgesic Agents for Relief of Intractable Cancer-Related Pain. Journal of Pharmaceutical Sciences, 2015, 104(7), 2334–2344. doi: 10.1002/jps.24497
  20. Duong, H.T.T.; Dong, Z.; Su, L; Boyer, C.; George, J.; Davis, T.P.; Wang, J. The Use of Nanoparticles to Deliver Nitric Oxide to Hepatic Stellate Cells for Treating Liver Fibrosis and Portal Hypertension. Small, 2015, 11(19), 2291–2304. doi: 10.1002/smll.201402870
  21. Chen, K.; Xu, X.; Guo, J.W.; Zhang, X.; Han, S.; Wang, R.; Li, X.; Zhang, J. Enhanced Intracellular Delivery and Tissue Retention of Nanoparticles by Mussel-Inspired Surface Chemistry. Biomacromolecules, 2015, 16(11), 3574–3583. doi: 10.1021/acs.biomac.5b01056
  22. Lin, Y.-A.; Cheetham, A.G.; Zhang, P.; Ou, Y.-C.; Li, Y.; Liu, G.; Hermida Merino, D.; Hamley, I.W.; Cui, H. Multi-Walled Nanotubes Formed by Catanionic Mixtures of Drug Amphiphiles. ACS Nano, 2014, 8(12), 12690-12700. doi: 10.1021/nn505688b
  23. Graen, T.M.D.; Hoefling, M.; Grubmüller, H. AMBER-DYES: Characterization of Charge Fluctuations and Force Field Parameterization of Fluorescent Dyes for Molecular Dynamics Simulations. Journal of Chemical Theory and Computation, 2014, 10(12), 5505-5512. doi: 10.1021/ct500869p
  24. Lu, H.D.; Soranno, D.E.; Rodell, C.B.; Kim, I.L.; Burdick, J.A. Secondary Photocrosslinking of Injectable Shear-Thinning Dock-and-Lock Hydrogels. Advanced Healthcare Materials, 2013, 2(7), 1028-1036. doi: 10.1002/adhm.201200343
  25. Yang, H.; Mao, H.; Wan, Z.; Zhu, A.; Guo, M.; Li, Y.; Li, X.; Wan, J.; Yang, X.; Shuai, X. et al. Micelles assembled with carbocyanine dyes for theranostic near-infrared fluorescent cancer imaging and photothermal therapy. Biomaterials, 2013, 34(36), 9124-9133. doi: 10.1016/j.biomaterials.2013.08.022
  26. Zhou, K.; Liu, H.; Zhang, S.; Huang, X.; Wang, Y.; Huang, G.; Sumer, B.D.; Gao, J. Multicolored pH-Tunable and Activatable Fluorescence Nanoplatform Responsive to Physiologic pH Stimuli. Journal of the American Chemical Society, 2012, 134(18), 7803-7811. doi: 10.1021/ja300176w

Cyanine7.5 амин

  1. Hauser-Kawaguchi, A.; Milne, M.; Li, F.; Lee, T.Y.; Luyt, L.G. The development of a near infrared inulin optical probe for measuring glomerular filtration rate. International Journal of Biological Macromolecules, 2019, 123, 255–260. doi: 10.1016/j.ijbiomac.2018.11.034
  2. Li, Y.; Xiao, Y.; Lin, H.-P.; Reichel, D.; Bae, Y.; Lee, E.Y.; Jiang, Y.; Huang, X.; Yang, C.; Wang, Z. In vivo β-catenin attenuation by the integrin α5-targeting nano-delivery strategy suppresses triple negative breast cancer stemness and metastasis. Biomaterials, 2019, 188, 160–172. doi: 10.1016/j.biomaterials.2018.10.019
  3. Gurnani, Pratik and Sanchez-Cano, C.; Abraham, K.; Xandri-Monje, H.; Cook, A.B.; Hartlieb, M.; Lévi, F.; Dallmann, R.; Perrier, S. RAFT Emulsion Polymerization as a Platform to Generate Well-Defined Biocompatible Latex Nanoparticles. Macromolecular Bioscience, 2018, 18(10), e1800213. doi: 10.1002/mabi.201800213
  4. Tabe, H.; Sukenobe, K.; Kondo, T.; Sakurai, A.; Maruo, M.; Shimauchi, A.; Hirano, M.; Uno, S.-N.; Kamiya, M.; Urano, Y.; Matsushita, M.; Fujiyoshi, S. Cryogenic Fluorescence Localization Microscopy of Spectrally Selected Individual FRET Pairs in a Water Matrix. The Journal of Physical Chemistry B, 2018, 122(27), 6906–6911. doi: 10.1021/acs.jpcb.8b03977
  5. Souchek, J.J.; Wojtynek, N.E.; Payne, W.M.; Holmes, M.B.; Dutta, S.; Qi, B.; Datta, K.; LaGrange, C.A.; Mohs, A.M. Hyaluronic acid formulation of near infrared fluorophores optimizes surgical imaging in a prostate tumor xenograft. Acta Biomaterialia, 2018, 75, 323–333. doi: 10.1016/j.actbio.2018.06.016
  6. Mondal, G.; Almawash, S.; Chaudhary, A.K.; Mahato, R.I. EGFR-Targeted Cationic Polymeric Mixed Micelles for Co-delivery of Gemcitabine and miR-205 for treating Advanced Pancreatic Cancer. Molecular Pharmaceutics, 2017, 14(9), 3121–3133. doi: 10.1021/acs.molpharmaceut.7b00355
  7. Payne, W.M.; Hill, T.K.; Svechkarev, D.; Holmes, M.B.; Sajja, B.R.; Mohs, A.M. Multimodal Imaging Nanoparticles Derived from Hyaluronic Acid for Integrated Preoperative and Intraoperative Cancer Imaging. Contrast Media & Molecular Imaging, 2017, 2017, Article ID 9616791. doi: 10.1155/2017/9616791
  8. Ta, H.T.; Li, Z.; Hagemeyer, C.E.; Cowin, G.; Zhang, S.; Palasubramaniam, J.; Alt, K.; Wang, X.; Peter, K.; Whittaker, A.K. Molecular imaging of activated platelets via antibody-targeted ultra-small iron oxide nanoparticles displaying unique dual MRI contrast. Biomaterials, 2017, 134, 31–42. doi: 10.1016/j.biomaterials.2017.04.037
  9. Cheng, J.; Feng, S.; Han, S.; Zhang, X.; Chen, Y.; Zhou, X.; Wang, R.; Li, X.; Hu, H.; Zhang, J. Facile Assembly of Cost-Effective and Locally Applicable or Injectable Nanohemostats for Hemorrhage Control. ACS Nano, 2016, 10(11), 9957&ndash9973. doi: 10.1021/acsnano.6b04124
  10. Hill, T.K.; Kelkar, S.S.; Wojtynek, N.E.; Souchek, J.J:; Payne, W.M.; Stumpf, K.; Marini, F.C.; Mohs, A.M. Near Infrared Fluorescent Nanoparticles Derived from Hyaluronic Acid Improve Tumor Contrast for Image-Guided Surgery. Theranostics, 2016, 6(13), 2314–2328. doi: 10.7150/thno.16514
  11. Kelkar, S.S.; Hill, T.K.; Marini, F.C.; Mohs, A.M. Near infrared fluorescent nanoparticles based on hyaluronic acid: self-assembly, optical properties, and cell interaction. Acta Biomaterialia, 2016, 36, 112–121. doi: 10.1016/j.actbio.2016.03.024
  12. Saadat, E.; Shakor, N.; Gholami, M.; Dorkoosh, F.A. Hyaluronic acid based micelle for articular delivery of triamcinolone, preparation, in vitro and in vivo evaluation. International Journal of Pharmaceutics, 2015, 489(1–2), 218–225. doi: 10.1016/j.ijpharm.2015.05.001

Cyanine7.5 гидразид

  1. Liu, S.; Dozois, M.D.; Chang, C.N.; Ahmad, A.; Ng, D.L.T.; Hileeto, D.; Liang, H.; Reyad, M.-M.; Boyd, S.; Jones, L.W.; Gu, F.X. Prolonged Ocular Retention of Mucoadhesive Nanoparticle Eye Drop Formulation Enables Treatment of Eye Diseases Using Significantly Reduced Dosage. Molecular Pharmaceutics, 2016, 13(9), 2897–2905. doi: 10.1021/acs.molpharmaceut.6b00445

Cyanine7.5 карбоновая кислота

  1. Luthman, A.S. Wide-Field fHSI with a Linescan SRDA. In: Spectrally Resolved Detector Arrays for Multiplexed Biomedical Fluorescence Imaging (Springer Thesis), 2018, 51–85. doi: 10.1007/978-3-319-98255-7_3
  2. Nunes, R.; Araújo, F.; Tavares, J.; Sarmento, B.; das Neves, J. Surface modification with polyethylene glycol enhances colorectal distribution and retention of nanoparticles. European Journal of Pharmaceutics and Biopharmaceutics, 2018, 130, 200–206. doi: 10.1016/j.ejpb.2018.06.029
  3. Roberts, S.; Andreou, C.; Choi, C.; Donabedian, P.; Jayaraman, M.; Pratt, E.C.; Tang, J.; Pérez-Medina, C.; de la Cruz, M.J.; Mulder, W.J.M.; Grimm, J.; Kircher, M.; Reiner, T. Sonophore-enhanced nanoemulsions for optoacoustic imaging of cancer. Chemical Science, 2018, 9(25), 5646–5657. doi: 10.1039/C8SC01706A
  4. Luthman, A.S.; Dumitru, S.; Quiros-Gonzalez, I.; Joseph, J.; Bohndiek, S.E. Fluorescence hyperspectral imaging (fHSI) using a spectrally resolved detector array. Journal of Biophotonics, 2017, 10(6–7), 840–853. doi: 10.1002/jbio.201600304
  5. Shen, T.; Guan, S.; Gan, Z.; Zhang, G.; Yu, Q. Polymeric Micelles with Uniform Surface Properties and Tunable Size and Charge: Positive Charges Improve Tumor Accumulation. Biomacromolecules, 2016, 17(5), 1801–1810. doi: 10.1021/acs.biomac.6b00234
  6. Ravar, F.; Saadat, E.; Gholami, M.; Dehghankelishady, P.; Mahdavi, M.; Azami, S.; Dorkoosh, F.A. Hyaluronic acid-coated liposomes for targeted delivery of paclitaxel, in-vitro characterization and in-vivo evaluation. Journal of Controlled Release, 2016, 229, 10–22. doi: 10.1016/j.jconrel.2016.03.012
  7. Du, N.; Guo, W.; Yu, Q.; Guan, S.; Guo, L.; Shen, T.; Tang, H.; Gan, Z. Poly(D,L-lactic acid)-block-poly(N-(2-hydroxypropyl)methacrylamide) nanoparticles for overcoming accelerated blood clearance and achieving efficient anti-tumor therapy. Polymer Chemistry, 2016, 7(36), 5719–5729. doi: 10.1039/c6py01113f
  8. Rodell, C.B.; Rai, R.; Faubel, S.; Burdick, J.A.; Soranno, D.E. Local Immunotherapy via Delivery of Interleukin-10 and Transforming Growth Factor β Antagonist for Treatment of Chronic Kidney Disease. Journal of Controlled Release, 2015, 206, 131–139. doi: 10.1016/j.jconrel.2015.03.025
  9. Rodell, C.B.; Wade, R.J.; Purcell, B.P.; Dusaj, N.N.; Burdick, J.A. Selective Proteolytic Degradation of Guest–Host Assembled, Injectable Hyaluronic Acid Hydrogels. ACS Biomaterials Science & Engineering, 2015, 1(4), 277–286. doi: 10.1021/ab5001673
  10. Wade, R.J.; Bassin, E.J.; Rodell, C.B.; Burdick, J.A. Protease-degradable electrospun fibrous hydrogels. Nature Communications, 2015, 6, 6639. doi: 10.1038/ncomms7639

Cyanine7.5 малеимид

  1. Men, Y.; Peng, S.; Yang, P.; Jiang, Q.; Zhang, Y.; Shen, B.; Dong, P.; Pang, Z.; Yang, W. Biodegradable Zwitterionic Nanogels with Long Circulation for Antitumor Drug Delivery. ACS Applied Materials & Interfaces, 2018, 10(28), 23509–23521. doi: 10.1021/acsami.8b03943

DMS(O)MT аминолинк C6

  1. Aparin, I.O.; Farzan, V.M.; Veselova, O.A.; Chistov, A.A.; Podkolzin, A.T.; Ustinov, A.V.; Shipulin, G.A.; Formanovsky, A.A.; Korshun, V.A.; Zatsepin, T.S. 1-Phenylethynylpyrene (PEPy) as a novel blue-emitting dye for qPCR assay. Analyst, 2016, 141, 1331–1338. doi: 10.1039/c5an01767j

EdU (5-этинил-2'-дезоксиуридин)

  1. Hernandez-Segura, A.; Brandenburg, S.; Demaria, M. Induction and Validation of Cellular Senescence in Primary Human Cells. Journal of Visualized Experiments, 2018, 136, e57782. doi: 10.3791/57782

FAM (флуоресцеин) азид, 5-изомер

  1. Haider, N.; Dutt, P.; van de Kooij, B.; Yaffe, M.B.; Stambolic, V. NEK10 tyrosine phosphorylates p53 and controls its transcriptional activity. bioRxiv. doi: 10.1101/516971
  2. Feltes, M.; Moores, S.; Gale, S.E.; Krishnan, K.; Mydock-McGrane, L.; Covey, D.F.; Ory, D.S.; Schaffer, J.E. Synthesis and characterization of diazirine alkyne probes for the study of intracellular cholesterol trafficking. Journal of Lipid Research, in press. doi: 10.1194/jlr.D091470
  3. Delasoie, J.; Rossier, J.; Haeni, L.; Rothen-Rutishauser, B.; Zobi, F. Slow-targeted release of a ruthenium anticancer agent from vitamin B12 functionalized marine diatom microalgae. Dalton Transactions, 2018, 47(48), 17221–17232. doi: 10.1039/c8dt02914h
  4. Ta, D.T.; Vanella, R.; Nash, M.A. Bioorthogonal Elastin-like Polypeptide Scaffolds for Immunoassay Enhancement. ACS Applied Materials & Interfaces, 2018, 10(36), 30147–30154. doi: 10.1021/acsami.8b10092
  5. Dutta, D.; Lai, K.-Y.; Reyes-Ordoñez, A.; Chen, J.; van der Donk, W.A. Lanthionine synthetase C-like protein 2 (LanCL2) is Important for Adipogenic Differentiation. Journal of Lipid Research, 2018, 59(8), 1433–1445. doi: 10.1194/jlr.M085274
  6. Ganapathy, U.S.; Bai, L.; Wei, L.; Eckartt, K.A.; Lett, C.M.; Previti, M.L.; Carrico, I.S.; Seeliger, J.C. Compartment-Specific Labeling of Bacterial Periplasmic Proteins by Peroxidase-Mediated Biotinylation. ACS Infectious Diseases, 2018, 4(6), 918–925. doi: 10.1021/acsinfecdis.8b00044
  7. Su, H.; Liu, Z.; Liu, Y.; Ma, V.P.-Y.; Blanchard, A.; Zhao, J.; Galior, K.; Dyer, R.B.; Salaita, K. Light-Responsive Polymer Particles as Force Clamps for the Mechanical Unfolding of Target Molecules. Nano Letters, 2018, 18(4), 2630–2636. doi: 10.1021/acs.nanolett.8b00459
  8. Long, M.J.C.; Urul, D.A.; Chawla, S.; Lin, H.-Y.; Zhao, Y.; Haegele, J.A.; Wang, Y.; Aye, Y. Precision Electrophile Tagging in Caenorhabditis elegans. Biochemistry, 2018, 57(2), 216–220. doi: 10.1021/acs.biochem.7b00642
  9. Fatona, A.; Berry, R.M.; Brook, M.A.; Moran-Mirabal, J.M. Versatile Surface Modification of Cellulose Fibres and Cellulose Nanocrystals through Modular Triazinyl Chemistry. Chemistry of Materials, 2018, 30(7), 2424–2435. doi: 10.1021/acs.chemmater.8b00511
  10. Pink, M.; Verma, N.; Zerries, A.; Schmitz-Spanke, S. Dose-dependent response to 3-nitrobenzanthrone exposure in human urothelial cancer cells. Chemical Research in Toxicology, 2017, 30(10), 1855–1864. doi: 10.1021/acs.chemrestox.7b00174
  11. Guttenplan, A.P.M.; Young, L.J.; Matak-Vinkovic, D.; Kaminski, C.F.; Knowles, T.P.J.; Itzhaki, L.S. Nanoscale click-reactive scaffolds from peptide self-assembly. Journal of Nanobiotechnology, 2017, 15, 70. doi: 10.1186/s12951-017-0300-7
  12. Ruhl, K.E; Rovis, T. Visible Light-Gated Cobalt Catalysis for a Spatially and Temporally Resolved [2+2+2] Cycloaddition. Journal of the American Chemical Society, 2016, 138(48), 15527–15530. doi: 10.1021/jacs.6b08792
  13. Berte, N.; Piee-Staffa, A.; Piecha, N.; Wang, M.; Borgmann, K.; Kaina, B.; Nikolova, T. Targeting homologous recombination by pharmacological inhibitors enhances the killing response of glioblastoma cells treated with alkylating drugs. Molecular Cancer Therapeutics, 2016, 15(11), 2665–2678. doi: 10.1158/1535-7163.mct-16-0176
  14. Ngo, J.T.; Adams, S.R.; Deerinck, T.J.; Boassa, D.; Rodriguez-Rivera, F.; Palida, S.F.; Bertozzi, C.R.; Ellisman, M.H.; Tsien, R.Y. Click-EM for imaging metabolically tagged nonprotein biomolecules. Nature Chemical Biology, 2016, 12(6), 459–465. doi: 10.1038/nchembio.2076
  15. Li, Z.; Liu, Z.; Chen, Z.; Ju, E.; Li, W.; Ren, J.; Qu, X. Bioorthogonal chemistry for selective recognition, separation and killing bacteria over mammalian cells. Chemical Communications, 2016, 52(17), 3482–3485. doi: 10.1039/c5cc10625g

FAM (флуоресцеин) азид, 6-изомер

  1. Haider, N.; Dutt, P.; van de Kooij, B.; Yaffe, M.B.; Stambolic, V. NEK10 tyrosine phosphorylates p53 and controls its transcriptional activity. bioRxiv. doi: 10.1101/516971
  2. Feltes, M.; Moores, S.; Gale, S.E.; Krishnan, K.; Mydock-McGrane, L.; Covey, D.F.; Ory, D.S.; Schaffer, J.E. Synthesis and characterization of diazirine alkyne probes for the study of intracellular cholesterol trafficking. Journal of Lipid Research, in press. doi: 10.1194/jlr.D091470
  3. Ruhl, K.E; Rovis, T. Visible Light-Gated Cobalt Catalysis for a Spatially and Temporally Resolved [2+2+2] Cycloaddition. Journal of the American Chemical Society, 2016, 138(48), 15527–15530. doi: 10.1021/jacs.6b08792
  4. Berte, N.; Piee-Staffa, A.; Piecha, N.; Wang, M.; Borgmann, K.; Kaina, B.; Nikolova, T. Targeting homologous recombination by pharmacological inhibitors enhances the killing response of glioblastoma cells treated with alkylating drugs. Molecular Cancer Therapeutics, 2016, 15(11), 2665–2678. doi: 10.1158/1535-7163.mct-16-0176
  5. Ngo, J.T.; Adams, S.R.; Deerinck, T.J.; Boassa, D.; Rodriguez-Rivera, F.; Palida, S.F.; Bertozzi, C.R.; Ellisman, M.H.; Tsien, R.Y. Click-EM for imaging metabolically tagged nonprotein biomolecules. Nature Chemical Biology, 2016, 12(6), 459–465. doi: 10.1038/nchembio.2076
  6. Kryvalap, Y.; Lo, C.-W.; Manuylova, E.; Baldzizhar, R.; Jospe, N.; Czyzyk, J. Antibody Response to Serpin B13 Induces Adaptive Changes in Mouse Pancreatic Islets and Slows Down the Decline in the Residual Beta Cell Function in Children with Recent Onset of Type 1 Diabetes Mellitus. Journal of Biological Chemistry, 2016, 291(1), 266–278. doi: 10.1074/jbc.M115.687848

FAM (флуоресцеин) алкин, 5-изомер

  1. Rojas-Sánchez, L.; Sokolova, V.; Riebe, S.; Voskuhl, J.; Epple, M. Covalent Surface Functionalization of Calcium Phosphate Nanoparticles with Fluorescent Dyes by Copper-Catalysed and by Strain-Promoted Azide-Alkyne Click Chemistry. ChemNanoMat, in press. doi: 10.1002/cnma.201800509
  2. Ganapathy, U.S.; Bai, L.; Wei, L.; Eckartt, K.A.; Lett, C.M.; Previti, M.L.; Carrico, I.S.; Seeliger, J.C. Compartment-Specific Labeling of Bacterial Periplasmic Proteins by Peroxidase-Mediated Biotinylation. ACS Infectious Diseases, 2018, 4(6), 918–925. doi: 10.1021/acsinfecdis.8b00044
  3. Stadler, D.; Siribbal, S.M.; Gessner, I.; Öz, S.; Ilyas, S.; Mathur, S. Asymmetric attachment and functionalization of plasmonic nanoparticles on ceramic interfaces. Journal of Nanostructure in Chemistry, 2018, 8(1), 33–44. doi: 10.1007/s40097-018-0252-y
  4. Shi, P.; Ju, E.; Yan, Z.; Gao, N.; Wang, J.; Hou, J.; Zhang, Y.; Ren, J.; Qu, X. Spatiotemporal control of cell-cell reversible interactions using molecular engineering. Nature communications, 2016, 7, 13088. doi: 10.1038/ncomms13088
  5. Lu, X.; Jia, F.; Tan, X.; Wang, D.; Cao, X.; Zheng, J.; Zhang, K. Effective Antisense Gene Regulation via Noncationic, Polyethylene Glycol Brushes. Journal of the American Chemical Society, 2016, 138(29), 9097–9100. doi: 10.1021/jacs.6b05787
  6. Ilnitskaya, E.V.; Kononevich, Y.N.; Muzafarov, A.M.; Rzhevskiy, S.A.; Shadrin, I.A.; Babaev, E.V.; Martynov, V.I.; Pakhomov, A.A. Preparation and application of a BODIPY-labeled probe for a real-time polymerase chain reaction. Russian Journal of Bioorganic Chemistry, 2015, 41(4), 451–453. doi: 10.1134/S1068162015040068

FAM (флуоресцеин) алкин, 6-изомер

  1. Machado, Y.; Duinkerken, S.; Hoepflinger, V.; Mayr, M.; Korotchenko, E.; Kurtaj, A.; Pablos, I.; Steiner, M.; Stoecklinger, A.; Lübbers, J.; Schmid, M.; Ritter, U.; Scheiblhofer, S.; Ablinger, M.; Wally, V.; Hochmann, S.; Raninger, A.M.; Strunk, D.; van Kooyk, Y.; Thalhamer, J.; Weiss, R. Synergistic effects of dendritic cell targeting and laser-microporation on enhancing epicutaneous skin vaccination efficacy. Journal of Controlled Release, 2017, 266, 87–99. doi: 10.1016/j.jconrel.2017.09.020
  2. Shi, P.; Ju, E.; Yan, Z.; Gao, N.; Wang, J.; Hou, J.; Zhang, Y.; Ren, J.; Qu, X. Spatiotemporal control of cell-cell reversible interactions using molecular engineering. Nature communications, 2016, 7, 13088. doi: 10.1038/ncomms13088

FAM активированный эфир, 6-изомер

  1. Evans, L.E.; Jones, K.; Cheeseman, M.D. Targeting secondary protein complexes in drug discovery: studying the druggability and chemical biology of the HSP70/BAG1 complex. Chemical Communications, 2017, 53(37), 5167–5170. doi: 10.1039/c7cc01376k
  2. Warminski, M.; Sikorski, P.J.; Warminska, Z.; Lukaszewicz, M.; Kropiwnicka, A.; Zuberek, J.; Darzynkiewicz, E.; Kowalska, J.; Jemielity, J. Amino-functionalized 5' cap analogs as tools for site-specific sequence-independent labeling of messenger RNA. Bioconjugate Chemistry, 2017, 28(7), 1978–1992. doi: 10.1021/acs.bioconjchem.7b00291
  3. Horning, D.P.; Joyce, G.F. Amplification of RNA by an RNA polymerase ribozyme. Proceedings of the National Academy of Sciences of the United States of America, 2016, 113(35), 9786–9791. doi: 10.1073/pnas.1610103113

FAM малеимид, 6-изомер

  1. Yu, C.; Tang, J.; Loredo, A.; Chen, Y.; Jung, S.Y.; Jain, A.; Gordon, A.; Xiao, H. Proximity-Induced Site-Specific Antibody Conjugation. Bioconjugate Chemistry, 2018, 29(11), 3522–3526. doi: 10.1021/acs.bioconjchem.8b00680

FAM фосфорамидит, 6-изомер

  1. Zhou, Z.; Liu, S.; Zhang, Y.; Yang, X.; Ma, Y.; Guan, Z.; Wu, Y.; Zhang, L.; Yang, Z. Reductive nanocomplex encapsulation of cRGD-siRNA conjugates for enhanced targeting to cancer cells. International Journal of Nanomedicine, 2017, 12, 7255–7272. doi: 10.2147/ijn.S136726

JOE азид, 5- изомер

  1. Nåbo, L.J.; Madsen, C.S.; Jensen, K.J.; Kongsted, J.; Astakhova, K. Ultramild Protein-Mediated Click Chemistry Creates Efficient Oligonucleotide Probes for Targeting and Detecting Nucleic Acids. ChemBioChem, 2015, 16(8), 1163–1167. doi: 10.1002/cbic.201500145

R110 азид, 5-изомер

  1. Nåbo, L.J.; Madsen, C.S.; Jensen, K.J.; Kongsted, J.; Astakhova, K. Ultramild Protein-Mediated Click Chemistry Creates Efficient Oligonucleotide Probes for Targeting and Detecting Nucleic Acids. ChemBioChem, 2015, 16(8), 1163–1167. doi: 10.1002/cbic.201500145
  2. Shieh, P.; Siegrist, M.S.; Cullen, A.J.; Bertozzi, C.R. Imaging bacterial peptidoglycan with near-infrared fluorogenic azide probes. Proceedings of the National Academy of Sciences of the U.S.A., 2014, 111(15), 5456–5461. doi: 10.1073/pnas.1322727111
  3. Okholm, A.; Kjems, J.; Astakhova, K. Fluorescence detection of natural RNA using rationally designed "clickable" oligonucleotide probes. RSC Advances, 2014, 4(86), 45653–45656. doi: 10.1039/c4ra07165d

R110 азид, 6-изомер

  1. Shieh, P.; Siegrist, M.S.; Cullen, A.J.; Bertozzi, C.R. Imaging bacterial peptidoglycan with near-infrared fluorogenic azide probes. Proceedings of the National Academy of Sciences of the U.S.A., 2014, 111(15), 5456–5461. doi: 10.1073/pnas.1322727111

ROX активированный эфир, 5-изомер

  1. Konopka, C.J.; Wozniak, M.; Hedhli, J.; Ploska, A.; Schwartz-Duval, A.; Siekierzycka, A.; Pan, D.; Munirathinam, G.; Dobrucki, I.T.; Kalinowski, L.; Dobrucki, L.W. Multimodal imaging of the receptor for advanced glycation end-products with molecularly targeted nanoparticles. Theranostics, 2018, 8(18), 5012–5024. doi: 10.7150/thno.24791

ROX активированный эфир, 6-изомер

  1. Konopka, C.J.; Wozniak, M.; Hedhli, J.; Ploska, A.; Schwartz-Duval, A.; Siekierzycka, A.; Pan, D.; Munirathinam, G.; Dobrucki, I.T.; Kalinowski, L.; Dobrucki, L.W. Multimodal imaging of the receptor for advanced glycation end-products with molecularly targeted nanoparticles. Theranostics, 2018, 8(18), 5012–5024. doi: 10.7150/thno.24791

ROX референсный краситель

  1. Schmidt, N.; Kollewe, A.; Constantin, C.E.; Henrich, S.; Ritzau-Jost, A.; Bildl, W.; Saalbach, A.; Hallermann, S.; Kulik, A.; Fakler, B.; Schulte, U. Neuroplastin and Basigin Are Essential Auxiliary Subunits of Plasma Membrane Ca2+-ATPases and Key Regulators of Ca2+ Clearance. Neuron, 2017, 96(4), 827–838.e9. doi: 10.1016/j.neuron.2017.09.038

ROX-азид, 5-изомер

  1. Feltes, M.; Moores, S.; Gale, S.E.; Krishnan, K.; Mydock-McGrane, L.; Covey, D.F.; Ory, D.S.; Schaffer, J.E. Synthesis and characterization of diazirine alkyne probes for the study of intracellular cholesterol trafficking. Journal of Lipid Research, in press. doi: 10.1194/jlr.D091470
  2. Verardi, R.; Kim, J.-S.; Ghirlando, R.; Banerjee, A. Structural Basis for Substrate Recognition by the Ankyrin Repeat Domain of Human DHHC17 Palmitoyltransferase. Structure, 2017, 25(9), 1337–1347. doi: 10.1016/j.str.2017.06.018
  3. Bak, D.W.; Pizzagalli, M.D.; Weerapana, E. Identifying Functional Cysteine Residues in the Mitochondria. ACS Chemical Biology, 2017, 12(4), 947–957. doi: 10.1021/acschembio.6b01074
  4. Nåbo, L.J.; Madsen, C.S.; Jensen, K.J.; Kongsted, J.; Astakhova, K. Ultramild Protein-Mediated Click Chemistry Creates Efficient Oligonucleotide Probes for Targeting and Detecting Nucleic Acids. ChemBioChem, 2015, 16(8), 1163–1167. doi: 10.1002/cbic.201500145
  5. Astakhova, I.K.; Wengel, J. Interfacing Click Chemistry with Automated Oligonucleotide Synthesis for the Preparation of Fluorescent DNA Probes Containing Internal Xanthene and Cyanine Dyes. Chemistry - a European Journal, 2013, 19(3), 1112-1122. doi: 10.1002/chem.201202621
  6. Liboska, R.; Ligasová, A.; Strunin, D.; Rosenberg, I.; Koberna, K. Most Anti-BrdU Antibodies React with 2'-Deoxy-5-Ethynyluridine ‒ The Method for the Effective Suppression of This Cross-Reactivity. PLoS ONE, 2012, 7(12), e51679. doi: 10.1371/journal.pone.0051679

SYBR Green I для ПЦР реального времени, 100x

  1. Segal, E.S.; Gritsenko, V.; Levitan, A.; Yadav, B.; Dror, N.; Steenwyk, J.L.; Silberberg, Y.; Mielich, K.; Rokas, A.; Gow, N.A.R.; Kunze, R.; Sharan, R.; Berman, J. Gene Essentiality Analyzed by In Vivo Transposon Mutagenesis and Machine Learning in a Stable Haploid Isolate of Candida albicans. mBio, 2018, 9(5), e02048-18. doi: 10.1128/mBio.02048-18
  2. Maximova, N.; Koroleva, A.; Sitnikova, T.; Khanaev, I.; Bukin, Y.; Kirilchik, S. Age Dynamics of Telomere Length of Baikal Gastropods is Sex Specific and Multidirectional. Folia Biologica (Kraków), 2017, 65(4), 187–197. doi: 10.3409/fb65_4.187
  3. Schmidt, N.; Kollewe, A.; Constantin, C.E.; Henrich, S.; Ritzau-Jost, A.; Bildl, W.; Saalbach, A.; Hallermann, S.; Kulik, A.; Fakler, B.; Schulte, U. Neuroplastin and Basigin Are Essential Auxiliary Subunits of Plasma Membrane Ca2+-ATPases and Key Regulators of Ca2+ Clearance. Neuron, 2017, 96(4), 827–838.e9. doi: 10.1016/j.neuron.2017.09.038
  4. Sharangdhar, T.; Sugimoto, Y.; Heraud-Farlow, J.; Fernández-Moya, S.M.; Ehses, J.; Ruiz de Los Mozos, I.; Ule, J.; Kiebler, M.A. A retained intron in the 3'-UTR of Calm3 mRNA mediates its Staufen2- and activity-dependent localization to neuronal dendrites. EMBO Reports, 2017, 18(10), 1762–1774. doi: 10.15252/embr.201744334
  5. Revalde, J.L.; Li, Y.; Wijeratne, T.S.; Bugde, P.; Hawkins, B.C.; Rosengren, R.J.; Paxton, J.W. Curcumin and its cyclohexanone analogue inhibited human Equilibrative nucleoside transporter 1 (ENT1) in pancreatic cancer cells. European Journal of Pharmacology, 2017, 803, 167–173. doi: 10.1016/j.ejphar.2017.03.055
  6. Wu, Z.-G.; Jiang, W.; Chen, S.-L.; Mantri, N.; Tao, Z.-M.; Jiang, C.-X. Insights from the Cold Transcriptome and Metabolome of Dendrobium officinale: Global Reprogramming of Metabolic and Gene Regulation Networks during Cold Acclimation. Frontiers in Plant Science, 2016, 7, 1653. doi: 10.3389/fpls.2016.01653
  7. Brauer, V.S.; Stomp, M.; Bouvier, T.; Fouilland, E.; Leboulanger, C.; Confurius-Guns, V.; Weissing, F.J.; Stal, L.J.; Huisman, J. Competition and facilitation between the marine nitrogen-fixing cyanobacterium Cyanothece and its associated bacterial community. Frontiers in Microbiology, 2015, 5, 795. doi: 10.3389/fmicb.2014.00795

SYBR Green I раствор для прокраски гелей, 10000x

  1. Komarova, N.; Andrianova, M.; Glukhov, S.; Kuznetsov, A. Selection, Characterization, and Application of {ssDNA} Aptamer against Furaneol. Molecules, 2018, 23(12), 3159. doi: 10.3390/molecules23123159
  2. Zietzer, A.; Buschmann, E.E.; Janke, D.; Li, L.; Brix, M.; Meyborg, H.; Stawowy, P.; Jungk, C.; Buschmann, I.; Hillmeister, P. Acute Physical Exercise and Long-Term Individual Shear Rate Therapy Increase Telomerase Activity in Human Peripheral Blood Mononuclear Cells. Acta Physiologica, 2017, 220(2), 251–262. doi: 10.1111/apha.12820
  3. Diaz-Romero, J.; Kürsener, S.; Kohl, S.; Nesic, D. S100B+A1 CELISA: A Novel Potency Assay and Screening Tool for Redifferentiation Stimuli of Human Articular Chondrocytes. Journal of Cellular Physiology, 2017, 232(6), 1559–1570. doi: 10.1002/jcp.25682
  4. Richter-Heitmann, T.; Eickhorst, T.; Knauth, S.; Friedrich, M.W.; Schmidt, H. Evaluation of Strategies to Separate Root-Associated Microbial Communities: A Crucial Choice in Rhizobiome Research. Frontiers in Microbiology, 2016, 7, 773. doi: 10.3389/fmicb.2016.00773
  5. Jain, D.; Siede, W. Rad5 Template Switch Pathway of DNA Damage Tolerance Determines Synergism between Cisplatin and NSC109268 in Saccharomyces cerevisiae. PLoS ONE, 2013, 8(10), e77666. doi: 10.1371/journal.pone.0077666
  6. Song, C.-X.; Sun, Y.; Dai, Q.; Lu, X.-Y.; Yu, M.; Yang, C.-G.; He, C. Detection of 5-Hydroxymethylcytosine in DNA by Transferring a Keto-Glucose by Using T4 Phage beta-Glucosyltransferase. ChemBioChem, 2011, 12(11), 1682-1685. doi: 10.1002/cbic.201100278
  7. Song, C.-X.; Yu, M.; Dai, Q.; He, C. Detection of 5-hydroxymethylcytosine in a combined glycosylation restriction analysis (CGRA) using restriction enzyme Taq[alpha]I. Bioorganic & Medicinal Chemistry Letters, 2011, 21(17), 5075-5077. doi: 10.1016/j.bmcl.2011.03.118

Sulfo-Cyanine3 азид

  1. Doll, F.; Steimbach, R.; Zumbusch, A. Direct Imaging of Protein-Specific Methylation in Mammalian Cells. Chembiochem, in press. doi: 10.1002/cbic.201800787
  2. Melnychuk, N.; Klymchenko, A.S. DNA-Functionalized Dye-Loaded Polymeric Nanoparticles: Ultrabright FRET Platform for Amplified Detection of Nucleic Acids. Journal of the American Chemical Society, 2018, 140(34), 10856–10865. doi: 10.1021/jacs.8b05840
  3. Hernandez-Segura, A.; Brandenburg, S.; Demaria, M. Induction and Validation of Cellular Senescence in Primary Human Cells. Journal of Visualized Experiments, 2018, 136, e57782. doi: 10.3791/57782
  4. Wong, S.Z.H.; Scott, E.P.; Mu, W.; Guo, X.; Borgenheimer, E.; Freeman, M.; Ming, G.-L.; Wu, Q.-F.; Song, H.; Nakagawa, Y. In vivo clonal analysis reveals spatiotemporal regulation of thalamic nucleogenesis. PLoS Biology, 2018, 16, e2005211. doi: 10.1371/journal.pbio.2005211
  5. Konishcheva, E.V.; Zhumaev, U.E.; Meier, W.P. PEO-b-PCL-b-PMOXA Triblock Copolymers: From Synthesis to Microscale Polymersomes with Asymmetric Membrane. Macromolecules, 2017, 50(4), 1512–1520. doi: 10.1021/acs.macromol.6b02743
  6. Sun, L.; Gai, Y.; Anderson, C.J.; Zeng, D. Highly-efficient and versatile fluorous-tagged Cu(I)-catalyzed azide–alkyne cycloaddition ligand for preparing bioconjugates. Chemical Communications, 2015, 51, 17072–17075. doi: 10.1039/C5CC06858D
  7. Haller, A.; Altman, R.B.; Souliere, M.F.; Blanchard, S.C.; Micura, R. Folding and ligand recognition of the TPP riboswitch aptamer at single-molecule resolution. Proceedings of the National Academy of Sciences of the U.S.A., 2013, 110(11), 4188-4193. doi: 10.1073/pnas.1218062110

Sulfo-Cyanine3 активированный эфир

  1. Meena, G.G.; Jain, A.; Parks, J.; Stambaugh, A.; Patterson, J.; Hawkins, A.; Schmidt, H. Integration of sample preparation and analysis on an optofluidic chip for multi-target disease detection. Lab on a Chip, 2018, 18(23), 3678–3686. doi: 10.1039/c8lc00966j
  2. Zadeh, P.S.N.; do Valle Gomes, M.Z.; Abrahamsson, M.; Palmqvist, A.; Åkerman, B. Measuring Viscosity inside Mesoporous Silica Using Protein-Bound Molecular Rotor Probe. Physical Chemistry Chemical Physics, 2018, 20(36), 23202–23213. doi: 10.1039/C8CP01063C
  3. Gu, R.; Oweida, T.; Yingling, Y.G.; Chilkoti, A.; Zauscher, S. Enzymatic synthesis of nucleobase-modified single-stranded DNA offers tunable resistance to nuclease degradation. Biomacromolecules, 2018, 19(8), 3525–3535. doi: 10.1021/acs.biomac.8b00816
  4. Zadeh, P.S.N.; do Valle Gomes, M.Z.; Åkerman, B.; Palmqvist, A.E.C. Förster resonance energy transfer study of the improved biocatalytic conversion of CO2 to formaldehyde by co-immobilization of enzymes in siliceous mesostructured cellular foams. ACS Catalysis, 2018, 8(8), 7251–7260. doi: 10.1021/acscatal.8b01806
  5. Stambaugh, A.; Parks, J.W.; Stott, M.A.; Meena, G.G.; Hawkins, A.R.; Schmidt, H. Optofluidic detection of Zika nucleic acid and protein biomarkers using multimode interference multiplexing. Biomedical Optics Express, 2018, 9(8), 3725–3730. doi: 10.1364/BOE.9.003725
  6. Selnihhin, D.; Sparvath, S.M.; Preus, S.; Birkedal, V.; Andersen, E.S. Multi-Fluorophore DNA Origami Beacon as a Biosensing Platform. ACS Nano, 2018, 12(6), 5699–5708. doi: 10.1021/acsnano.8b01510
  7. Sallada, N.D.; Dunn, K.J.; Berger, B.W. A structural and functional role for disulfide bonds in a class II hydrophobin. Biochemistry, 2018, 57(5), 645–653. doi: 10.1021/acs.biochem.7b01166
  8. Zabara, A.; Meikle, T.G.; Trenker, R.; Yao, S.; Newman, J.; Peat, T.S.; Separovic, F.; Conn, C.E.; Call, M.J.; Call, M.E.; Landau, E.M.; Drummond, C.J. Lipidic Cubic Phase-Induced Membrane Protein Crystallization: Interplay Between Lipid Structure, Mesophase Properties, and Crystallogenesis. Crystal Growth and Design, 2017, 17(11), 5667–5674. doi: 10.1021/acs.cgd.7b00519
  9. Ozcelik, D.; Jain, A.; Stambaugh, A.; Stott, M.A.; Parks, J.W.; Hawkins, A.; Schmidt, H. Scalable Spatial-Spectral Multiplexing of Single-Virus Detection Using Multimode Interference Waveguides. Scientific Reports, 2017, 7, 12199. doi: 10.1038/s41598-017-12487-0
  10. Shi, X.; Yu, C.Y.Y.; Su, H.; Kwok, R.T.K.; Jiang, M.; He, Z.; Lam, J.W.Y.; Tang, B.Z. A Red-emissive antibody–AIEgen conjugate for turn-on and wash-free imaging of specific cancer cells. Chemical Science, 2017, 8(10), 7014–7024. doi: 10.1039/C7SC01054K
  11. Schneider, J.R.; Carias, A.M.; Bastian, A.R.; Cianci, G.C.; Kiser, P.F.; Veazey, R.S.; Hope, T.J. Long-term direct visualization of passively transferred fluorophore-conjugated antibodies. Journal of Immunological Methods, 2017, 450, 66–72. doi: 10.1016/j.jim.2017.07.009
  12. Huang, T.-Y.; Chang, C.-K.; Kao, Y.-F.; Chin, C.-H.; Ni, C.-W.; Hsu, H.-Y.; Hu, N.-J.; Hsieh, L.-C.; Chou, S.-H.; Lee, I.-R.; Hou, M.-H. Parity-dependent hairpin configurations of repetitive DNA sequence promote slippage associated with DNA expansion. Proceedings of the National Academy of Sciences of the USA, 2017, 114(36), 9535–9540. doi: 10.1073/pnas.1708691114
  13. Barnett, D.; Liu, Y.; Partyka, K.; Huang, Y.; Tang, H.; Hostetter, G.; Brand, R.E.; Singhi, A.D.; Drake, R.R.; Haab, B.B. The CA19-9 and Sialyl-TRA Antigens Define Separate Subpopulations of Pancreatic Cancer Cells. Scientific Reports, 2017, 7, 4020. doi: 10.1038/s41598-017-04164-z
  14. Korkmaz, E.; Friedrich, E.E.; Ramadan, M.H.; Erdos, G.; Mathers, A.R.; Ozdoganlar, O.B.; Washburn, N.R.; Falo, Jr, L.D. Tip-Loaded Dissolvable Microneedle Arrays Effectively Deliver Polymer-Conjugated Antibody Inhibitors of Tumor-Necrosis-Factor-Alpha Into Human Skin. Journal of Pharmaceutical Sciences, 2016, 105(11), 3453–3457. doi: 10.1016/j.xphs.2016.07.008
  15. Zhou, L.; Wang, K.; Wu, Z.; Dong, H.; Sun, H.; Cheng, X.; Zhang, H.; Zhou, H.; Jia, C.; Jin, Q.; Mao, H.; Coll, J.-L.; Zhao, J. Investigation of Controllable Nanoscale Heat-Denatured Bovine Serum Albumin Films on Graphene. Langmuir, 2016, 32(48), 12623–12631. doi: 10.1021/acs.langmuir.6b03296
  16. Zhang, X.; MIn, L.; Jia, C. Application of Wavelet Transform Algorithm and Rolling Ball Algorithm in Single Molecule Fluorescence Resonance Energy Transfer Images. Progress in Biochemistry and Biophysics, 2016, 43(10), 997–1003. doi: 10.16476/j.pibb.2016.0218
  17. Søndergaard, S.; Aznauryan, M.; Haustrup, E.K.; Schiøtt, B.; Birkedal, V.; Corry, B. Dynamics of Fluorescent Dyes Attached to G-Quadruplex DNA and their Effect on FRET Experiments. ChemPhysChem, 2015, 16(12), 2562–2570. doi: 10.1002/cphc.201500271
  18. Wang, W.; Kapur, A.; Ji, X.; Safi, M.; Palui, G.; Palomo, V.; Dawson, P.E.; Mattoussi, H. Photoligation of an Amphiphilic Polymer with Mixed Coordination Provides Compact and Reactive Quantum Dots. Journal of the American Chemical Society, 2015, 137(16), 5438–5451. doi: 10.1021/jacs.5b00671
  19. Reid, D.A.; Keegan, S.; Leo-Macias, A.; Watanabe, G.; Strande, N.T.; Chang, H.H.; Oksuz, B.A.; Fenyo, D.; Lieber, M.R.; Ramsden, D.A.; Rothenberg, E. Organization and dynamics of the nonhomologous end-joining machinery during DNA double-strand break repair. Proceedings of the National Academy of Sciences of the U.S.A., 2015, 112(20), E2575–E2584. doi: 10.1073/pnas.1420115112
  20. Glembockyte, V.; Lincoln, R.; Cosa, G. Cy3 Photoprotection Mediated by Ni2+ for Extended Single-Molecule Imaging: Old Tricks for New Techniques. Journal of the American Chemical Society, 2015, 137(3), 1116–1122. doi: 10.1021/ja509923e
  21. Martell, D.J.; Joshi, C.P.; Gaballa, A.; Santiago, A.G.; Chen, T.-Y.; Jung, W.; Helmann, J.D.; Chen, P. Metalloregulator CueR biases RNA polymerase's kinetic sampling of dead-end or open complex to repress or activate transcription. Proceedings of the National Academy of Sciences of the U.S.A., 2015, 112(44), 13467–13472. doi: 10.1073/pnas.1515231112
  22. Graen, T.M.D.; Hoefling, M.; Grubmüller, H. AMBER-DYES: Characterization of Charge Fluctuations and Force Field Parameterization of Fluorescent Dyes for Molecular Dynamics Simulations. Journal of Chemical Theory and Computation, 2014, 10(12), 5505-5512. doi: 10.1021/ct500869p
  23. Wang, W.; Ji, X.; Na, H.B.; Safi, M.; Smith, A.; Palui, G.; Perez, J.M.; Mattoussi, H. Design of a Multi-Dopamine-Modified Polymer Ligand Optimally Suited for Interfacing Magnetic Nanoparticles with Biological Systems. Langmuir, 2014, 30(21), 6197-6208. doi: 10.1021/la500974r
  24. Aldeek, F.; Muhammed, M.A.H.; Palui, G.; Zhan, N.; Mattoussi, H. Growth of Highly Fluorescent Polyethylene Glycol- and Zwitterion-Functionalized Gold Nanoclusters. ACS Nano, 2013, 7(3), 2509-2521. doi: 10.1021/nn305856t
  25. Zhan, N.; Palui, G.; Safi, M.; Ji, X.; Mattoussi, H. Multidentate Zwitterionic Ligands Provide Compact and Highly Biocompatible Quantum Dots. Journal of the American Chemical Society, 2013, 135(37), 13786-13795. doi: 10.1021/ja405010v
  26. Kim, W.-J.; Kim, A.; Huh, C.; Park, C.W.; Ah, C.S.; Kim, B.K.; Yang, J.-H.; Chung, K.H.; Choi, Y.H.; Hong, J. et al. Photo selective protein immobilization using bovine serum albumin. Applied Surface Science, 2012, 261, 880-889. doi: 10.1016/j.apsusc.2012.08.111

Sulfo-Cyanine3 алкин

  1. Rambarran, T.; Gonzaga, F.; Fatona, A.; Coulson, M.; Saem, S.; Moran-Mirabal, J.; Brook, M.A. Bonding and in-channel microfluidic functionalization using the huisgen cyclization. ournal of Polymer Science Part A: Polymer Chemistry, 2018, 56(6), 589–597. doi: 10.1002/pola.28930
  2. Konishcheva, E.V.; Zhumaev, U.E.; Meier, W.P. PEO-b-PCL-b-PMOXA Triblock Copolymers: From Synthesis to Microscale Polymersomes with Asymmetric Membrane. Macromolecules, 2017, 50(4), 1512–1520. doi: 10.1021/acs.macromol.6b02743

Sulfo-Cyanine3 амин

  1. Zhang, Q.; Scigliano, A.; Biver, T.; Pucci, A.; Swager, T.M. Interfacial Bioconjugation on Emulsion Droplet for Biosensors. Bioorganic & Medicinal Chemistry, 2018, 26(19), 5307–5313. doi: 10.1016/j.bmc.2018.04.020
  2. Sobotzki, N.; Schafroth, M.A.; Rudnicka, A.; Koetemann, A.; Marty, F.; Goetze, S.; Yamauchi, Y.; Carreira, E.M.; Wollscheid, B. HATRIC-based identification of receptors for orphan ligands. Nature Communications, 2018, 9, 1519. doi: 10.1038/s41467-018-03936-z

Sulfo-Cyanine3 карбоновая кислота

  1. Cho, U.; Riordan, D.P.; Ciepla, P.; Kocherlakota, K.S.; Chen, J.K.; Harbury, P.B. Ultrasensitive optical imaging with lanthanide lumiphores. Nature Chemical Biology, 2018, 14(1), 15–21. doi: 10.1038/nchembio.2513
  2. Spears, B.R.; Marin, M.A.; Chaker, A.N.; Lampley, M.W.; Harth, E. Precise Microscale Polymeric Networks through Piezoelectronic Inkjet Printing. ACS Biomaterials Science & Engineering, 2016, 2(8), 1265–1272. doi: 10.1021/acsbiomaterials.6b00175

Sulfo-Cyanine3 малеимид

  1. Ni, Y.; Arts, R.; Merkx, M. Ratiometric bioluminescent sensor proteins based on intramolecular split luciferase complementation. ACS Sensors, in press. doi: 10.1021/acssensors.8b01381
  2. Agrawalla, B.K.; Wang, T.; Riegger, A.; Domogalla, M.P.; Steinbrink, K.; Dörfler, T.; Chen, X.; Boldt, F.; Lamla, M.; Michaelis, J.; Kuan, S.L.; Weil, T. Chemoselective Dual and Triple Labelling of Native and Recombinant Proteins. Bioconjugate Chemistry, 2018, 29(1), 29–34. doi: 10.1021/acs.bioconjchem.7b00675
  3. Yao, L.; Li, Q.; Guan, Y.; Zhu, X.X.; Zhang, Y. Tetrahedral, Octahedral, and Triangular Dipyramidal Microgel Clusters with Thermosensitivity Fabricated from Binary Colloidal Crystals Template and Thiol–Ene Reaction. ACS Macro Letters, 2018, 7, 80–84. doi: 10.1021/acsmacrolett.7b00935
  4. Steffen, W.; Ko, F.C.; Patel, J.; Lyamichev, V.; Albert, T.; Benz, J.; Rudolph, M.G.; Bergmann, F.; Streidl, T.; Kratzsch, P.; Boenitz-Dulat, M.; Oelschlaegel, T.; Schraeml, M. Discovery of a microbial transglutaminase enabling highly site-specific labeling of proteins. Journal of Biological Chemistry, 2017, 292(38), 15622–15635. doi: 10.1074/jbc.M117.797811
  5. Allen, C.D.; Chen, M.Y.; Trick, A.Y.; Le, D.T.; Ferguson, A.L.; Link, A.J. Thermal Unthreading of the Lasso Peptides Astexin-2 and Astexin-3. ACS Chemical Biology, 2016, 11(11), 3043–3051. doi: 10.1021/acschembio.6b00588
  6. Shebl, B., Menke, D.E.; Pennella, M.; Poudyal, R.R.; Burke, D.H.; Cornish, P.V. Preparation of ribosomes for smFRET studies: A simplified approach. Archives of Biochemistry and Biophysics, 2016, 603, 118–130. doi: 10.1016/j.abb.2016.05.010

Sulfo-Cyanine5 азид

  1. Maerle, A.V.; Simonova, M.A.; Pivovarov, V.D.; Voronina, D.V.; Drobyazina, P.E.; Trofimov, D.Y.; Alekseev, L.P.; Zavriev, S.K.; Ryazantsev, D.Y. Development of the covalent antibody-DNA conjugates technology for detection of IgE and IgM antibodies by immuno-PCR. PloS One, 2019, 14(1), e0209860. doi: 10.1371/journal.pone.0209860
  2. Marín-Caba, L.; Chariou, P.L.; Pesquera, C.; Correa-Duarte, M.A.; Steinmetz, N.F. Tobacco Mosaic Virus-Functionalized Mesoporous Silica Nanoparticles, a Wool-Ball-like Nanostructure for Drug Delivery. Langmuir, 2019, 35(1), 203–211. doi: 10.1021/acs.langmuir.8b03337
  3. Pitek, A.S.; Hu, H.; Shukla, S.; Steinmetz, N.F. Cancer Theranostic Applications of Albumin-Coated Tobacco Mosaic Virus Nanoparticles. ACS Applied Materials & Interfaces, 2018, 10(46), 39468–39477. doi: 10.1021/acsami.8b12499
  4. Karas, J.; Turner, B.J.; Shabanpoor, F. The Assembly of Fluorescently Labeled Peptide-Oligonucleotide Conjugates via Orthogonal Ligation Strategies. Methods in Molecular Biology, 2018, 1282, 355–363. doi: 10.1007/978-1-4939-8651-4_22
  5. Lomakin, Y.; Kudriaeva, A.; Kostin, N.; Terekhov, S.; Kaminskaya, A.; Chernov, A.; Zakharova, M.; Ivanova, M.; Simaniv, T.; Telegin, G.; Gabibov, A.; Belogurov, A. Diagnostics of autoimmune neurodegeneration using fluorescent probing. Scientific Reports, 2018, 8, 12679. doi: 10.1038/s41598-018-30938-0
  6. Franke, C.E.; Czapar, A.E.; Patel, R.B.; Steinmetz, N.F. Tobacco Mosaic Virus-Delivered Cisplatin Restores Efficacy in Platinum-Resistant Ovarian Cancer Cells. Molecular Pharmaceutics, 2018, 15(8), 2922–2931. doi: 10.1021/acs.molpharmaceut.7b00466
  7. Gupta, S.; M-Redmond, T; Meng, F.; Tidball, A.; Akil, H.; Watson, S.; Parent, J.M.; Uhler, M.; others. Fibroblast Growth Factor 2 Regulates Activity and Gene Expression of Human Postmitotic Excitatory Neuron. Journal of Neurochemistry, 2018, 145(3), 188–203. doi: 10.1111/jnc.14255
  8. Gulati, N.M.; Pitek, A.S.; Czapar, A.E.; Stewart, P.L.; Steinmetz, N.F. The in vivo fates of plant viral nanoparticles camouflaged using self-proteins: overcoming immune recognition. Journal of Materials Chemistry B, 2018, 6(15), 2204–2216. doi: 10.1039/C7TB03106H
  9. Zhao, M.; Steffen, F.D.; and Börner, R.; Schaffer, M.F.; Sigel, R.K.O.; Freisinger, E. Site-specific dual-color labeling of long RNAs for single-molecule spectroscopy. Nucleic Acids Research, 2018, 46(3), e13. doi: 10.1093/nar/gkx1100
  10. Rambarran, T.; Gonzaga, F.; Fatona, A.; Coulson, M.; Saem, S.; Moran-Mirabal, J.; Brook, M.A. Bonding and in-channel microfluidic functionalization using the huisgen cyclization. ournal of Polymer Science Part A: Polymer Chemistry, 2018, 56(6), 589–597. doi: 10.1002/pola.28930
  11. Rachel, N.M.; Toulouse, J.L.; Pelletier, J.N. Transglutaminase-Catalyzed Bioconjugation Using One-Pot Metal-Free Bioorthogonal Chemistry. Bioconjugate Chemistry, 2017, 28(10), 2518–2523. doi: 10.1021/acs.bioconjchem.7b00509
  12. Gulati, N.M.; Pitek, A.S.; Steinmetz, N.F.; Stewart, P.L. Cryo-electron tomography investigation of serum albumin-camouflaged tobacco mosaic virus nanoparticles. Nanoscale, 2017, 9(10), 3408–3425. doi: 10.1039/c6nr06948g
  13. Long, M.J.; Lin, H.-Y.; Parvez, S.; Zhao, Y.; Poganik, J.R.; Huang, P.; Aye, Y. β-TrCP1 Is a Vacillatory Regulator of Wnt Signaling. Cell Chemical Biology, 2017, 24(8), 944–957.e7. doi: 10.1016/j.chembiol.2017.06.009
  14. Parvez, S.; Long, M.J.C.; Lin, H.-Y.; Zhao, Y.; Haegele, J.A.; Pham, V.N.; Lee, D.K.; Aye, Y. T-REX on-demand redox targeting in live cells. Nature Protocols, 2016, 11(12), 2328–2356. doi: 10.1038/nprot.2016.114
  15. Farzan, V.M.; Aparin, I.O.; Veselova, O.A.; Podkolzin, A.T.; Shipulin, G.A.; Korshun, V.A.; Zatsepin, T.S. Cy5/BHQ dye-quencher pairs in fluorogenic qPCR probes: effects of charge and hydrophobicity. Analytical Methods, 2016, 8(29), 5826–5831. doi: 10.1039/c6ay01304j
  16. Pitek, A.S.; Jameson, S.A.; Veliz, F.A.; Shukla, S.; Steinmetz, N.F. Serum Albumin "Camouflage" of Plant Virus Based Nanoparticles Prevents Their Antibody Recognition and Enhances Pharmacokinetics. Biomaterials, 2016, 89, 89–97. doi: 10.1016/j.biomaterials.2016.02.032
  17. Bruckman, M.; Randolph, L.; Gulati, N.; Stewart, P.; Steinmetz, N.F. Silica mineralization of Gd(DOTA)-loaded viral nanoparticles enhances MRI relaxivity and avoids immune recognition. Journal of Materials Chemistry B, 2015, 3(38), 7503–7510. doi: 10.1039/c5tb01014d
  18. Li, F.; Dong, J.; Hu, X.; Gong, W.; Li, J.; Shen, J.; Tian, H.; Wang, J. A Covalent Approach for Site-Specific RNA Labeling in Mammalian Cells. Angewandte Chemie International Edition, 2015, 54(15), 4597–4602. doi: 10.1002/anie.201410433
  19. Maruani, A.; Smith, M.E.B.; Miranda, E.; Chester, K.A.; Chudasama, V.; Caddick, S. A plug-and-play approach to antibody-based therapeutics via a chemoselective dual click strategy. Nature communications, 2015, 6, 6645. doi: 10.1038/ncomms7645
  20. Nikić, I.; Kang, J.H.; Girona, G.E.; Aramburu, I.V.; Lemke, E.A. Labeling proteins on live mammalian cells using click chemistry. Nature Protocols, 2015, 10(5), 780–791. doi: 10.1038/nprot.2015.045
  21. Wen, A.M.; Infusino, M.; De Luca, A.; Kernan, D.L.; Czapar, A.E.; Strangi, G.; Steinmetz, N.F. Interface of Physics and Biology: Engineering Virus-Based Nanoparticles for Biophotonics. Bioconjugate Chemistry, 2015, 26(1), 51–62. doi: 10.1021/bc500524f
  22. Maruani, A.; Alom, S.; Canavelli, P.; Lee, M.T.W.; Morgan, R.E.; Chudasama, V.; Caddick, S. A mild TCEP-based para-azidobenzyl cleavage strategy to transform reversible cysteine thiol labelling reagents into irreversible conjugates. Chemical Communications, 2015, 51, 5279–5282. doi: 10.1039/c4cc08515a
  23. Bruckman, M.A.; Randolph, L.N.; VanMeter, A.; Hern, S.; Shoffstall, A.J.; Taurog, R.E.; Steinmetz, N.F. Biodistribution, pharmacokinetics, and blood compatibility of native and PEGylated tobacco mosaic virus nano-rods and -spheres in mice. Virology, 2014, 449, 163-173. doi: 10.1016/j.virol.2013.10.035
  24. Bruckman, M.A.; Steinmetz, N.F. Chemical Modification of the Inner and Outer Surfaces of Tobacco Mosaic Virus (TMV). Methods in Molecular Biology (Virus Hybrids as Nanomaterials), 2014, 1108, 173-185. doi: 10.1007/978-1-62703-751-8_13
  25. Sloniec, J.; Resch-Genger, U.; Hennig, A. Photophysics and Release Kinetics of Enzyme-Activatable Optical Probes Based on H-Dimerized Fluorophores on Self-Immolative Linkers. The Journal of Physical Chemistry B, 2013, 117(46), 14336-14344. doi: 10.1021/jp409388b

Sulfo-Cyanine5 активированный эфир

  1. Le, D.H.T.; Méndez-López, E.; Wang, C.; Commandeur, U.; Aranda, M.A.; Steinmetz, N.F. Biodistribution of Filamentous Plant Virus Nanoparticles: Pepino Mosaic Virus versus Potato Virus X. Biomacromolecules, 2019, 20(1), 469–477. doi: 10.1021/acs.biomac.8b01365
  2. Pirutin, S.K.; Efremova, M.V.; Yusipovich, A.I.; Turovetskii, V.B.; Maksimov, G.V.; Druzhko, A.B.; Mazhuga, A.G. Visualization and Cytotoxicity of Fluorescence-Labeled Dimeric Magnetite-Gold Nanoparticles Conjugated with Prostate-Specific Membrane Antigen in Mouse Macrophages. Bulletin of Experimental Biology and Medicine, 2019, 166(3), 386–389. doi: 10.1007/s10517-019-04356-9
  3. Lalonde, T.; Shepherd, T.G.; Dhanvantari, S.; Luyt, L.G. Stapled ghrelin peptides as fluorescent imaging probes. Peptide Science, 2019, 111(1), e24055. doi: 10.1002/pep2.24055
  4. Kluender, E.J.; Hedrick, J.L.; Brown, K.A.; Rao, R.; Meckes, B.; Du, J.S.; Moreau, L.M.; Maruyama, B.; Mirkin, C.A. Catalyst discovery through megalibraries of nanomaterials. Proceedings of the National Academy of Sciences of the United States of America, 2019, 116(1), 40–45. doi: 10.1073/pnas.1815358116
  5. Pawar, G.N.; Parayath, N.N.; Nocera, A.L.; Bleier, B.S.; Amiji, M.M. Direct CNS delivery of proteins using thermosensitive liposome-in-gel carrier by heterotopic mucosal engrafting. PLoS One, 2018, 13, e0208122. doi: 10.1371/journal.pone.0208122
  6. Swenson, S.; Minea, R.O.; Tuan, C.D.; Thein, T.-Z.; Chen, T.C.; Markland, F.S. A Novel Venom-Derived Peptide for Brachytherapy of Glioblastoma: Preclinical Studies in Mice. Molecules, 2018, 23(11), 2918. doi: 10.3390/molecules23112918
  7. Pitek, A.S.; Park, J.; Wang, Y.; Gao, H.; Hu, H.; Simon, D.I.; Steinmetz, N.F. Delivery of thrombolytic therapy using rod-shaped plant viral nanoparticles decreases the risk of hemorrhage. Nanoscale, 2018, 10(35), 16547–16555. doi: 10.1039/c8nr02861c
  8. Zadeh, P.S.N.; do Valle Gomes, M.Z.; Abrahamsson, M.; Palmqvist, A.; Åkerman, B. Measuring Viscosity inside Mesoporous Silica Using Protein-Bound Molecular Rotor Probe. Physical Chemistry Chemical Physics, 2018, 20(36), 23202–23213. doi: 10.1039/C8CP01063C
  9. Joshi, B.P.; Hardie, J.; Mingroni, M.A.; Farkas, M.E. Surface-Modified Macrophages Facilitate Tracking of Breast Cancer-Immune Interactions. ACS Chemical Biology, 2018, 13(8), 2339–2346. doi: 10.1021/acschembio.8b00509
  10. Babič, A.; Vinet, L.; Chellakudam, V.; Janikowska, K.; Allémann, E.; Lange, N. Squalene-PEG-exendin as high-affinity constructs for pancreatic beta-cells. Bioconjugate Chemistry, 2018, 29(8), 2531–2540. doi: 10.1021/acs.bioconjchem.8b00186
  11. Zadeh, P.S.N.; do Valle Gomes, M.Z.; Åkerman, B.; Palmqvist, A.E.C. Förster resonance energy transfer study of the improved biocatalytic conversion of CO2 to formaldehyde by co-immobilization of enzymes in siliceous mesostructured cellular foams. ACS Catalysis, 2018, 8(8), 7251–7260. doi: 10.1021/acscatal.8b01806
  12. Sarker, B.; Walter, C.; Pathak, A. Direct micropatterning of {ECM} proteins on functionalized polyacrylamide hydrogels shows geometric regulation of cell-cell junctions. ACS Biomaterials Science & Engineering, 2018, 4(7), 2340–2349. doi: 10.1021/acsbiomaterials.8b00331
  13. Blackman, L.D.; Varlas, S.; Arno, M.C.; Houston, Z.H.; Fletcher, N.L.; Thurecht, K.J.; Hasan, M.; Gibson, M.I.; O'Reilly, R.K. Confinement of Therapeutic Enzymes in Selectively Permeable Polymer Vesicles by Polymerization-Induced Self-Assembly (PISA) Reduces Antibody Binding and Proteolytic Susceptibility. Central Science, 2018, 4(6), 718–723. doi: 10.1021/acscentsci.8b00168
  14. Selnihhin, D.; Sparvath, S.M.; Preus, S.; Birkedal, V.; Andersen, E.S. Multi-Fluorophore DNA Origami Beacon as a Biosensing Platform. ACS Nano, 2018, 12(6), 5699–5708. doi: 10.1021/acsnano.8b01510
  15. Li, H.; Zhang, Z.; Bao, X.; Xu, G.; Yao, P. Fatty acid and quaternary ammonium modified chitosan nanoparticles for insulin delivery. Colloids and Surfaces, B: Biointerfaces, 2018, 170, 136–143. doi: 10.1016/j.colsurfb.2018.05.063
  16. Parayath, N.N.; Parikh, A.; Amiji, M.M. Repolarization of Tumor-Associated Macrophages in a Genetically Engineered Nonsmall Cell Lung Cancer Model by Intraperitoneal Administration of Hyaluronic Acid-Based Nanoparticles Encapsulating MicroRNA-125b. Nano Letters, 2018, 18(6), 3571–3579. doi: 10.1021/acs.nanolett.8b00689
  17. Volkov, I.L.; Lindén, M.; Aguirre Rivera, J.; Ieong, K.-W.; Metelev, M.; Elf, J.; Johansson, M. tRNA tracking for direct measurements of protein synthesis kinetics in live cells. Nature Chemical Biology, 2018, 14(6), 618–626. doi: 10.1038/s41589-018-0063-y
  18. Peng, S.; Wang, W.; Chen, C. Surface Transient Binding Based Fluorescence Correlation Spectroscopy (STB-FCS), a Simple and Easy-to-Implement Method to Extend the Upper Limit of Time Window to Seconds. The Journal of Physical Chemistry B, 2018, 122(18), 4844–4850. doi: 10.1021/acs.jpcb.8b03476
  19. Mietlicki-Baase, E.G.; Liberini, C.G.; Workinger, J.L.; Bonaccorso, R.L.; Borner, T.; Reiner, D.J.; Koch-Laskowski, K.; McGrath, L.E.; Lhamo, R.; Stein, L.M.; De Jonghe, B.C.; Holz, G.G.; Roth, C.L.; Doyle, R.P.; Hayes, M.R. A Vitamin B12 Conjugate of Exendin-4 Improves Glucose Tolerance Without Associated Nausea or Hypophagia in Rodents. Diabetes, Obesity & Metabolism, 2018, 20(5), 1223–1234. doi: 10.1111/dom.13222
  20. Kim, H.-Y.; Wang, X.; Kang, R.; Tang, D.; Boone, B.A.; Zeh, H.J.; Lotze, M.T.; Edwards, W.B. RAGE-specific single chain Fv for PET imaging of pancreatic cancer. PLoS One, 2018, 13(3), e0192821. doi: 10.1371/journal.pone.0192821
  21. Ghai, A.; Maji, D.; Rettig, M.; Chanswangphuwana, C.; DiPersio, J.; Akers, W.; Achilefu, S.; Dehdashti, F.; Vij, R.; Shokeen, M. Preclinical development of CD38-targeted [89Zr]Zr-DFO-daratumumab for imaging multiple myeloma. Journal of Nuclear Medicine, 2018, 59(2), 216–222. doi: 10.2967/jnumed.117.196063
  22. Lam, R.; Gondin, A.B.; Canals, M.; Kellam, B.; Briddon, S.J.; Graham, B.; Scammells, P.J. Fluorescently Labelled Morphine Derivatives for Bioimaging Studies. Journal of Medicinal Chemistry, 2018, 61(3), 1316–1329. doi: 10.1021/acs.jmedchem.7b01811
  23. Sallada, N.D.; Dunn, K.J.; Berger, B.W. A structural and functional role for disulfide bonds in a class II hydrophobin. Biochemistry, 2018, 57(5), 645–653. doi: 10.1021/acs.biochem.7b01166
  24. Wu, Y.; Zhang, L.; Cui, C.; Cansiz, S.; Liang, H.; Wu, C.; Teng, I.-T.; Chen, W.; Liu, Y.; Hou, W.; Zhang, X.; Tan, W. Enhanced Targeted Gene Transduction: AAV2 Vectors Conjugated to Multiple Aptamers via Reducible Disulfide Linkages. Journal of the American Chemical Society, 2018, 140(1), 2–5. doi: 10.1021/jacs.7b08518
  25. Ou, H.; Cheng, T.; Zhang, Y.; Liu, J.; Ding, Y.; Zhen, J.; Shen, W.; Xu, Y.; Yang, W.; Niu, P.; Liu, J.; An, Y.; Liu, Y.; Shi, L. Surface-adaptive Zwitterionic Nanoparticles for Prolonged Blood Circulation Time and Enhanced Cellular Uptake in Tumor Cells. Acta Biomaterialia, 2018, 65, 339–348. doi: 10.1016/j.actbio.2017.10.034
  26. Cioloboc, D.; Kennedy, C.; Boice, E.N.; Clark, E.R.; Kurtz, D.M. A Trojan Horse for Light-Triggered Bifurcated Production of Singlet Oxygen and Fenton-Reactive Iron Within Cancer Cells. Biomacromolecules, 2018, 19(1), 178–187. doi: 10.1021/acs.biomac.7b01433
  27. Lockhart, J.N.; Spoonmore, T.J.; McCurdy, M.W.; Rogers, B.R.; Guelcher, S.A.; Harth, E. Poly(glycidol) Coating on Ultrahigh Molecular Weight Polyethylene for Reduced Biofilm Growth. ACS Applied Materials & Interfaces, 2018, 10(4), 4050–4056. doi: 10.1021/acsami.7b15981
  28. Feiner-Gracia, N.; Beck, M.; Pujals, S.; Tosi, S.; Mandal, T.; Buske, C.; Linden, M.; Albertazzi, L. Super-Resolution Microscopy Unveils Dynamic Heterogeneities in Nanoparticle Protein Corona. Small, 2017, 13(41), 1701631. doi: 10.1002/smll.201701631
  29. Ozcelik, D.; Jain, A.; Stambaugh, A.; Stott, M.A.; Parks, J.W.; Hawkins, A.; Schmidt, H. Scalable Spatial-Spectral Multiplexing of Single-Virus Detection Using Multimode Interference Waveguides. Scientific Reports, 2017, 7, 12199. doi: 10.1038/s41598-017-12487-0
  30. Schneider, J.R.; Carias, A.M.; Bastian, A.R.; Cianci, G.C.; Kiser, P.F.; Veazey, R.S.; Hope, T.J. Long-term direct visualization of passively transferred fluorophore-conjugated antibodies. Journal of Immunological Methods, 2017, 450, 66–72. doi: 10.1016/j.jim.2017.07.009
  31. Pettersson, J.R.; Lanni, F.; Rule, G.S. Dual lifetimes for complexes between Glutathione-S-transferase (hGSTA1-1) and product-like ligands detected by single-molecule fluorescence imaging. Biochemistry, 2017, 56(31), 4073–4083. doi: 10.1021/acs.biochem.7b00030
  32. Barnett, D.; Liu, Y.; Partyka, K.; Huang, Y.; Tang, H.; Hostetter, G.; Brand, R.E.; Singhi, A.D.; Drake, R.R.; Haab, B.B. The CA19-9 and Sialyl-TRA Antigens Define Separate Subpopulations of Pancreatic Cancer Cells. Scientific Reports, 2017, 7, 4020. doi: 10.1038/s41598-017-04164-z
  33. George, J.T.; Srivatsan, S.G. Vinyluridine as a Versatile Chemoselective Handle for the Post-transcriptional Chemical Functionalization of RNA. Bioconjugate Chemistry, 2017, 28(5), 1529–1536. doi: 10.1021/acs.bioconjchem.7b00169
  34. Goto, A.; Yen, H.-C.; Anraku, Y.; Fukushima, S.; Lai, P.-S.; Kato, M.; Kishimura, A.; Kataoka, K. Facile Preparation of Delivery Platform of Water-Soluble Low-Molecular-Weight Drugs Based on Polyion Complex Vesicle (PICsome) Encapsulating Mesoporous Silica Nanoparticle. ACS Biomaterials Science & Engineering, 2017, 3(5), 807–815. doi: 10.1021/acsbiomaterials.6b00562
  35. Wong, A.S.M.; Czuba, E.; Chen, M.Z.; Yuen, D.; Cupic, K.I.; Yang, S.; Hodgetts, R.Y.; Selby, L.I.; Johnston, A.P.R.; Such, G.K. pH-Responsive Transferrin-pHlexi Particles Capable of Targeting Cells in Vitro. ACS Macro Letters, 2017, 6, 315–320. doi: 10.1021/acsmacrolett.7b00044
  36. Terekhov, S.S.; Smirnov, I.V.; Stepanova, A.V.; Bobik, T.V.; Mokrushina, Y.A.; Ponomarenko, N.A.; Belogurov, A.A.; Rubtsova, M.P.; Kartseva, O.V.; Gomzikova, M.O.; Moskovtsev, A.A.; Bukatin, A.S.; Dubina, M.V.; Kostryukova, E.S.; Babenko, V.V.; Vakhitova, M.T.; Manolov, A.I.; Malakhova, M.V.; Kornienko, M.A.; Tyakht, A.V.; Vanyushkina, A.A.; Ilina, E.N.; Masson, P.; Gabibov, A.g.; Altman, S. Microfluidic droplet platform for ultrahigh-throughput single-cell screening of biodiversity. Proceedings of the National Academy of Sciences of the U.S.A., 2017, 114(10), 2550–2555. doi: 10.1073/pnas.1621226114
  37. Masarapu, H.; Patel, B.K.; Chariou, P.L.; Hu, H.; Gulati, N.M.; Carpenter, B.L.; Ghiladi, R.A.; Shukla, S.; Steinmetz, N.F. Physalis Mottle Virus-Like Particles as Nanocarriers for Imaging Reagents and Drugs. Biomacromolecules, 2017, 18(12), 4141–4153. doi: 10.1021/acs.biomac.7b01196
  38. Zhang, X.; MIn, L.; Jia, C. Application of Wavelet Transform Algorithm and Rolling Ball Algorithm in Single Molecule Fluorescence Resonance Energy Transfer Images. Progress in Biochemistry and Biophysics, 2016, 43(10), 997–1003. doi: 10.16476/j.pibb.2016.0218
  39. Ye, R.; Zhu, C.; Song, Y.; Song, J.; Fu, S.; Lu, Q.; Yang, X.; Zhu, M.-J.; Du, D.; Li, H.; Lin, Y. One-pot bioinspired synthesis of all-inclusive protein–protein nanoflowers for point-of-care bioassay: detection of E. coli O157:H7 from milk. Nanoscale, 2016, 8(45), 18980–18986. doi: 10.1039/c6nr06870g
  40. Mattheolabakis, G.; Ling, D.; Ahmad, G.; Amiji, M. Enhanced Anti-Tumor Efficacy of Lipid-Modified Platinum Derivatives in Combination with Survivin Silencing siRNA in Resistant Non-Small Cell Lung Cancer. Pharmaceutical Research, 2016, 33(12), 2943–2953. doi: 10.1007/s11095-016-2016-z
  41. Machulkin, A.E.; Garanina, A.S.; Zhironkina, O.A.; Beloglazkina, E.K.; Zyk, N.V.; Savchenko, A.G.; Kotelyanskii, V.E.; Mazhuga, A.G. Nanohybride Materials Based on Magnetite-Gold Nanoparticles for Diagnostics of Prostate Cancer: Synthesis and In Vitro Testing. Bulletin of Experimental Biology and Medicine, 2016, 161(5), 706–710. doi: 10.1007/s10517-016-3490-3
  42. Li, Hong-Jun and Du, Jin-Zhi and Liu, Jing and Du, Xiao-Jiao and Shen, Song and Zhu, Yan-Hua and Wang, Xiaoyan and Ye, Xiaodong and Nie, Shuming and Wang, Jun. Smart Superstructures with Ultrahigh pH-Sensitivity for Targeting Acidic Tumor Microenvironment: Instantaneous Size Switching and Improved Tumor Penetration. ACS Nano, 2016, 10(7), 6753–6761. doi: 10.1021/acsnano.6b02326
  43. Wang, H.; Tang, L.; Liu, Y.; Dobrucka, I.T.; Dobrucki, L.W.; Yin, L.; Cheng, J. In Vivo Targeting of Metabolically Labeled Cancers with Ultra-Small Silica Nanoconjugates. Theranostics, 2016, 6(9), 1467–1476. doi: 10.7150/thno.16003
  44. Soodgupta, D.; Zhou, H.; Beaino, W.; Lu, L.; Rettig, M.; Snee, M.; Skeath, J.; DiPersio, J.F.; Akers, W.J.; Laforest, R.; Anderson, C.J.; Tomasson, M.H.; Shokeen, M. Ex Vivo and In Vivo Evaluation of Overexpressed VLA-4 in Multiple Myeloma Using LLP2A Imaging Agents. Journal of Nuclear Medicine, 2016, 57(4), 640–645. doi: 10.2967/jnumed.115.164624
  45. Ye, R.; Zhu, C.; Song, Y.; Lu, Q.; Ge, X.; Yang, X.; Zhu, M.-J.; Du, D.; Li, H.; Lin, Y. Bioinspired Synthesis of All-in-One Organic-Inorganic Hybrid Nanoflowers Combined with a Handheld pH Meter for On-Site Detection of Food Pathogen. Small, 2016, 12(23), 3094–3100. doi: 10.1002/smll.201600273
  46. Bruckman, M.A.; Czapar, A.E.; VanMeter, A.; Randolph, L.N.; Steinmetz, N.F. Tobacco mosaic virus-based protein nanoparticles and nanorods for chemotherapy delivery targeting breast cancer. Journal of Controlled Release, 2016, 231, 103–113. doi: 10.1016/j.jconrel.2016.02.045
  47. Sindhwani, S.; Syed, A.M.; Wilhelm, S.; Glancy, D.R.; Chen, Y.Y.; Dobosz, M.; Chan, W.C.W. Three-Dimensional Optical Mapping of Nanoparticle Distribution in Intact Tissues. ACS Nano, 2016, 10(5), 5468–5478. doi: 10.1021/acsnano.6b01879
  48. Sun, S.; Błażewska, K.M.; Kadina, A.P.; Kashemirov, B.A.; Duan, X.; Triffitt, J.T.; Dunford, J.E.; Russell, R.G.G.; Ebetino, F.H.; Roelofs, A.J.; Coxon, F.P.; Lundy, M.W.; McKenna, C.E. Fluorescent Bisphosphonate and Carboxyphosphonate Probes: A Versatile Imaging Toolkit for Applications in Bone Biology and Biomedicine. Bioconjugate Chemistry, 2016, 27(2), 329–340. doi: 10.1021/acs.bioconjchem.5b00369
  49. Wang, X.; Song, P.; Peng, L.; Tong, A.; Xiang, Y. Aggregation-Induced Emission Luminogen-Embedded Silica Nanoparticles Containing DNA Aptamers for Targeted Cell Imaging. ACS Applied Materials & Interfaces, 2016, 8(1), 609–616. doi: 10.1021/acsami.5b09644
  50. Zhao, Y.; Wei, Z.; Zhao, H.; Jia, J.; Chen, Z.; Zhang, S.; Ouyang, Z.; Ma, X.; Zhang, X. In situ Ion-Transmission Mass Spectrometry for Paper-Based Analytical Devices. Analytical Chemistry, 2016, 88(22), 10805–10810. doi: 10.1021/acs.analchem.6b03272
  51. Lehtivuori, H.; Bhattacharya, S.;Angenent-Mari, N.M.; Satyshur, K.A.; Forest, K.T. Removal of Chromophore-Proximal Polar Atoms Decreases Water Content and Increases Fluorescence in a Near Infrared Phytofluor. Frontiers in Molecular Biosciences, 2015, 2, 65. doi: 10.3389/fmolb.2015.00065
  52. Barlow, N.; Nasser, Y.; Zhao, P.; Sharma, N.; Guerrero-Alba, R.; Edgington-Mitchell, L.E.; Lieu, T.; Veldhuis, N.A.; Poole, D.P.; Conner, J.W.; Lindström, E.; Craig, A.W.; Graham, B.; Vanner, S.J.; Bunnett, N.W. Demonstration of elevated levels of active cathepsin S in dextran sulfate sodium colitis using a new activatable probe. Neurogastroenterology and Motility, 2015, 27(11), 1675–1680. doi: 10.1111/nmo.12656
  53. Singh, S.; Pal, K.; Yadav, J.; Tang, H.; Partyka, K.; Kletter, D.; Hsueh, P.; Ensink, E.; KC, B.; Hostetter, G.; Xu, H.E.; Bern, M.; Smith, D.F.; Mehta, A.S.; Brand, R.; Melcher, K.; Haab, B.B. Upregulation of Glycans Containing 3' Fucose in a Subset of Pancreatic Cancers Uncovered Using Fusion-Tagged Lectins. Journal of Proteome Research, 2015, 14(6), 2594–2605. doi: 10.1021/acs.jproteome.5b00142
  54. Hörner, A.; Hagendorn, T.; Schepers, U.; Bräse, S. Photophysical properties and synthesis of new dye-cyclooctyne conjugates for multicolor and advanced microscopy. Bioconjugate Chemistry, 2015, 26(4), 718–724. doi: 10.1021/acs.bioconjchem.5b00059
  55. Mahoney, D.; Owens, E.A.; Fan, C.; Hsiang, J.-C.; Henary, M.; Dickson, R.M. Tailoring Cyanine Dark States for Improved Optically Modulated Fluorescence Recovery. The Journal of Physical Chemistry B, 2015, 119(13), 4637–4643. doi: 10.1021/acs.jpcb.5b00777
  56. Han, Z.; Zhou, Z.; Shi, X.; Wang, J.; Wu, X.; Sun, D.; Chen, Y.; Zhu, H.; Magi-Galluzzi, C.; Lu, Z.-R. EDB fibronectin specific peptide for prostate cancer targeting. Bioconjugate Chemistry, 2015, 26(5), 830–838. doi: 10.1021/acs.bioconjchem.5b00178
  57. Aldeek, F.; Hawkins, D.; Palomo, V.; Safi, M.; Palui, G.; Dawson, P.E.; Alabugin, I.V.; Mattoussi, H. UV and Sunlight Driven Photoligation of Quantum Dots: Understanding the Photochemical Transformation of the Ligands. Journal of the American Chemical Society, 2015, 137(7), 2704–2714. doi: 10.1021/ja512802x
  58. Wen, A.M.; Infusino, M.; De Luca, A.; Kernan, D.L.; Czapar, A.E.; Strangi, G.; Steinmetz, N.F. Interface of Physics and Biology: Engineering Virus-Based Nanoparticles for Biophotonics. Bioconjugate Chemistry, 2015, 26(1), 51–62. doi: 10.1021/bc500524f
  59. Nakamura, T.; Sugihara, F.; Matsushita, H.; Yoshioka, Y.; Mizukami, S.; Kikuchi, K. Mesoporous silica nanoparticles for 19F magnetic resonance imaging, fluorescence imaging, and drug delivery. Chemical Science, 2015, 6, 1986–1990. doi: 10.1039/c4sc03549f
  60. Hsueh, P.-Y.; Edman, M.C.; Sun, G.; Shi, P.; Xu, S.; Lin, Y.-a.; Cui, H.; Hamm-Alvarez, S.F.; MacKay, J.A. Tear-mediated delivery of nanoparticles through transcytosis of the lacrimal gland. Journal of Controlled Release, 2015, 208, 2–13. doi: 10.1016/j.jconrel.2014.12.017
  61. Geertsema, H.J.; Duderstadt, K.E.; van Oijen, A.M. Single-molecule observation of prokaryotic DNA replication. Methods in Molecular Biology, 2015, 1300, 219–238. doi: 10.1007/978-1-4939-2596-4_14
  62. Nooney, R.I.; White, A.; O’Mahony, C.; O’Connell, C.; Kelleher, S.M.; Daniels, S.; McDonagh, C. Investigating the colloidal stability of fluorescent silica nanoparticles under isotonic conditions for biomedical applications. Journal of Colloid and Interface Science, 2015, 456, 50–58. doi: 10.1016/j.jcis.2015.05.051
  63. Santangelo, M.F.; Sciuto, E.L.; Busacca, A.C.; Petralia, S.; Conoci, S.; Libertino, S. SiPM as miniaturised optical biosensor for DNA-microarray applications. Sensing and Bio-Sensing Research, 2015, 6, 95–98. doi: 10.1016/j.sbsr.2015.08.003
  64. Sciuto, E.L.; Santangelo, M.F.; Villaggio, G.; Sinatra, F.; Bongiorno, C.; Nicotra, G.; Libertino, S. Photo-physical characterization of fluorophore Ru(bpy)32+ for optical biosensing applications. Sensing and Bio-Sensing Research, 2015, 6, 67–71. doi: 10.1016/j.sbsr.2015.09.003
  65. Hickey, S. F.; Hammond, M.C. Structure-Guided Design of Fluorescent S-Adenosylmethionine Analogs for a High-Throughput Screen to Target SAM-I Riboswitch RNAs. Chemistry & Biology, 2014, 21(3), 345–356. doi: 10.1016/j.chembiol.2014.01.004
  66. Terekhov, S.S.; Smirnov, I.V.; Shamborant, O.G.; Zenkova, M.A.; Chernolovskaya, E.L.; Gladkikh, D.V.; Murashev, A.N.; Dyachenko, I.A.; Knorre, V.D.; Belogurov, A.A.; Ponomarenko, N.A.; Deyev, S.M.; Vlasov, V.V.; Gabibov, A.G. Excessive Labeling Technique Provides a Highly Sensitive Fluorescent Probe for Real-time Monitoring of Biodegradation of Biopolymer Pharmaceuticals in vivo. Acta Naturae, 2014, 6(4), 54–59
  67. Ayala-Orozco, C.; Liu, J.G.; Knight, M.W.; Wang, Y.; Day, J.K.; Nordlander, P.; Halas, N.J. Fluorescence Enhancement of Molecules Inside a Gold Nanomatryoshka. Nano Letters, 2014, 14(5), 2926-2933. doi: 10.1021/nl501027j
  68. Brand, C.; Abdel-Atti, D.; Zhang, Y.; Carlin, S.; Clardy, S.M.; Keliher, E.J.; Weber, W.A.; Lewis, J.S.; Reiner, T. In Vivo Imaging of GLP-1R with a Targeted Bimodal PET/Fluorescence Imaging Agent. Bioconjugate Chemistry, 2014, 25(7), 1323-1330. doi: 10.1021/bc500178d
  69. Graen, T.M.D.; Hoefling, M.; Grubmüller, H. AMBER-DYES: Characterization of Charge Fluctuations and Force Field Parameterization of Fluorescent Dyes for Molecular Dynamics Simulations. Journal of Chemical Theory and Computation, 2014, 10(12), 5505-5512. doi: 10.1021/ct500869p
  70. Li, L.-L.; Xu, J.-H.; Qi, G.-B.; Zhao, X.; Yu, F.; Wang, H. Core-Shell Supramolecular Gelatin Nanoparticles for Adaptive and "On-Demand" Antibiotic Delivery. ACS Nano, 2014, 8(5), 4975-4983. doi: 10.1021/nn501040h
  71. Viehweger, K.; Barbaro, L.; García, K.P.; Joshi, T.; Geipel, G.; Steinbach, J.; Stephan, H.; Spiccia, L.; Graham, B. EGF Receptor-Targeting Peptide Conjugate Incorporating a Near-IR Fluorescent Dye and a Novel 1,4,7-Triazacyclononane-Based 64Cu(II) Chelator Assembled via Click Chemistry. Bioconjugate Chemistry, 2014, 25(5), 1011-1022. doi: 10.1021/bc5001388
  72. Zhou, Z.; Wu, X.; Kresak, A.; Griswold, M.; Lu, Z.-R. Peptide targeted tripod macrocyclic Gd(III) chelates for cancer molecular MRI. Biomaterials, 2013, 34(31), 7683-7693. doi: 10.1016/j.biomaterials.2013.06.057
  73. Zou, C.; Loka, R.S.; Zhang, Y.; Cairo, C.W. Glycoform Remodeling Generates a Synthetic T Cell Phenotype. Bioconjugate Chemistry, 2013, 24(6), 907-914. doi: 10.1021/bc300599w

Sulfo-Cyanine5 алкин

  1. Rojas-Sánchez, L.; Sokolova, V.; Riebe, S.; Voskuhl, J.; Epple, M. Covalent Surface Functionalization of Calcium Phosphate Nanoparticles with Fluorescent Dyes by Copper-Catalysed and by Strain-Promoted Azide-Alkyne Click Chemistry. ChemNanoMat, in press. doi: 10.1002/cnma.201800509
  2. Braselmann, E.; Wierzba, A.J.; Polaski, J.T.; Chromiński, M.; Holmes, Z.E.; Hung, S.-T.; Batan, D.; Wheeler, J.R.; Parker, R.; Jimenez, R.; Gryko, D.; Batey, R.T.; Palmer, A.E. A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells. Nature Chemical Biology, 2018, 14(10), 964–971. doi: 10.1038/s41589-018-0103-7
  3. Qu, S.; Shi, Y.; Benavides, S.; Hunter, A.J.; Gao, H.; Phillip, W.A. Copolymer Nanofilters with Charge-Patterned Domains for Enhanced Electrolyte Transport. Chemistry of Materials, 2017, 29(2), 762–772. doi: 10.1021/acs.chemmater.6b04660
  4. Ngambenjawong, C.; Gustafson, H.H.; Pineda, J.M.; Kacherovsky, N.A.; Cieslewicz, M.; Pun, S.H. Serum Stability and Affinity Optimization of an M2 Macrophage-Targeting Peptide (M2pep). Theranostics, 2016, 6(9), 1403–1414. doi: 10.7150/thno.15394

Sulfo-Cyanine5 амин

  1. Xie, J.; Yang, C.; Liu, Q.; Li, J.; Liang, R.; Shen, C.; Zhang, Y.; Wang, K.; Liu, L.; Shezad, K.; Sullivan, M.; Xu, Y.; Shen, G.; Tao, J.; Zhu, J.; Zhang, Z. Encapsulation of Hydrophilic and Hydrophobic Peptides into Hollow Mesoporous Silica Nanoparticles for Enhancement of Antitumor Immune Response. Small, 2017, 13(40), 1701741. doi: 10.1002/smll.201701741

Sulfo-Cyanine5 карбоновая кислота

  1. Ranjit, S.; Malacrida, L.; Gratton, E. Differences between FLIM phasor analyses for data collected with the Becker and Hickl SPC830 card and with the FLIMbox card. Microscopy Research and Technique, 2018, 81(9), 980–989. doi: 10.1002/jemt.23061
  2. Razgoniaeva, N.; Rogers, S.; Moroz, P.; Cassidy, J.; Zamkov, M. Improving the spectral resolution in fluorescence microscopy through shaped-excitation imaging. Methods and Applications in Fluorescence, 2018, 6(4), 045006. doi: 10.1088/2050-6120/aad81c
  3. Siltanen, C.A.; Cole, R.H.; Poust, S.; Chao, L.; Tyerman, J.; Kaufmann-Malaga, B.; Ubersax, J.; Gartner, Z.J.; Abate, A.R. An Oil-Free Picodrop Bioassay Platform for Synthetic Biology. Scientific Reports, 2018, 8, 7913. doi: 10.1038/s41598-018-25577-4
  4. Zhao, Y.; Zhang, W.; Li, C. Optimization of the conical mirror design based on Monte Carlo simulations for fluorescence molecular tomography. SPIE Proceedings: Multimodal Biomedical Imaging XIII, 2018, 10487, 104870M. doi: 10.1117/12.2290665
  5. Cho, U.; Riordan, D.P.; Ciepla, P.; Kocherlakota, K.S.; Chen, J.K.; Harbury, P.B. Ultrasensitive optical imaging with lanthanide lumiphores. Nature Chemical Biology, 2018, 14(1), 15–21. doi: 10.1038/nchembio.2513
  6. Than, A.; Liang, K.; Xu, S.; Sun, L.; Duan, H.; Xi, F.; Xu, C.; Chen, P. Transdermal Delivery of Anti-Obesity Compounds to Subcutaneous Adipose Tissue with Polymeric Microneedle Patches. Small Methods, 2017, 1(11), 1700269. doi: 10.1002/smtd.201700269
  7. Summer, D.; Grossrubatscher, L.; Petrik, M.; Michalcikova, T.; Novy, Z.; Rangger, C.; Klingler, M.; von Guggenberg, E.; Haubner, R.; Kaeopookum, P.; Haas, H.; Decristoforo, C. Developing targeted hybrid imaging probes by chelator scaffolding. Bioconjugate Chemistry, 2017, 28(6), 1722–1733. doi: 10.1021/acs.bioconjchem.7b00182
  8. Hatai, J.; Motiei, L.; Margulies, D. Analyzing Amyloid Beta Aggregates with a Combinatorial Fluorescent Molecular Sensor. Journal of the American Chemical Society, 2017, 139(6), 2136–2139. doi: 10.1021/jacs.6b10809
  9. Schlegel, I.; Muñoz-Espí, R.; Renz, P.; Lieberwirth, I.; Floudas, G.; Suzuki, Y.; Crespy, D.; Landfester, K. Crystallinity Tunes Permeability of Polymer Nanocapsules. Macromolecules, 2017, 50(12), 4725–4732. doi: 10.1021/acs.macromol.7b00667
  10. Liu, M.; Richardson, R.R.; Mountford, S.J.; Zhang, L.; Tempone, M.H.; Herzog, H.; Holliday, N.D.; Thompson, P.E. Identification of a Cyanine-Dye Labelled Peptidic Ligand for Y1R and Y4R, based upon the Neuropeptide Y C-terminal analogue, BVD-15. Bioconjugate Chemistry, 2016, 27(9), 2166–2175. doi: 10.1021/acs.bioconjchem.6b00376
  11. Gao, P.; Hunter, A.J.; Summe, M.J.; Phillip, W.A. A Method for the Efficient Fabrication of Multifunctional Mosaic Membranes by Inkjet Printing. ACS Applied Materials & Interfaces, 2016, 8(30), 19772–19779. doi: 10.1021/acsami.6b06048
  12. Calver, C.F.; Liu, H.-W.; Cosa, G. Exploiting Conjugated Polyelectrolyte Photophysics towards Monitoring Real-Time Lipid Membrane-Surface Interaction Dynamics at the Single Particle Level. Langmuir, 2015, 31(43), 11842–11850. doi: 10.1021/acs.langmuir.5b00979
  13. Lee, S.J.; Shim, Y.H.; Oh, J.-S.; Jeong, Y.-I. Park, I.-K.; Lee, H.C. Folic-acid-conjugated pullulan/poly(DL-lactide-co-glycolide) graft copolymer nanoparticles for folate-receptor-mediated drug delivery. Nanoscale Research Letters, 2015, 10, 43. doi: 10.1186/s11671-014-0706-1
  14. Tucker, K.R.; Block, E.R.; Levitan, E.S. Action potentials and amphetamine release antipsychotic drug from dopamine neuron synaptic VMAT vesicles. Proceedings of the National Academy of Sciences of the U.S.A., 2015, 112(32), E4485–E4494. doi: 10.1073/pnas.1503766112
  15. Lin, W.; Liu, J.; Jeffries, C.; Yang, L.; Lu, Y.; Lee, R.E.; Chen, T. Development of BODIPY FL Vindoline as a Novel and High-Affinity Pregnane X Receptor Fluorescent Probe. Bioconjugate Chemistry, 2014, 25(9), 1664-1677. doi: 10.1021/bc5002856

Sulfo-Cyanine5 малеимид

  1. Baranova, N.; Radler, P.; Hernandez-Rocamora, V.M.; Alfonso, C.; Lopez-Pelegrin, M.; Rivas, G.; Vollmer, W.; Loose, M. FtsZ assembles the bacterial cell division machinery by a diffusion-and-capture mechanism. bioRxiv. doi: 10.1101/485656
  2. Graham, T.G.W.; Carney, S.M.; Walter, J.C.; Loparo, J.J. A single XLF dimer bridges DNA ends during nonhomologous end joining. Nature Structural & Molecular Biology, 2018, 25(9), 877–884. doi: 10.1038/s41594-018-0120-y
  3. Torres, O.B.; Duval, A.J.; Sulima, A.; Antoline, J.F.G.; Jacobson, A.E.; Rice, K.C.; Alving, C.R.; Matyas, G.R. A rapid solution-based method for determining the affinity of heroin hapten-induced antibodies to heroin, its metabolites, and other opioids. Analytical and Bioanalytical Chemistry, 2018, 410(16), 3885–3903. doi: 10.1007/s00216-018-1060-4
  4. Liu, L.; Zhang, C.; Li, Z.; Wang, C.; Bi, J.; Yin, S.; Wang, Q.; Yu, R.; Liu, Y.D.; Su, Z. Albumin binding domain fusing R/K-X-X-R/K sequence for enhancing tumor delivery of doxorubicin. Molecular Pharmaceutics, 2017, 14(11), 3739–3749. doi: 10.1021/acs.molpharmaceut.7b00497
  5. Guo, L.Y.; Allu, P.K.; Zandarashvili, L.; McKinley, K.L.; Sekulic, N.; Dawicki-McKenna, J.M.; Fachinetti, D.; Logsdon, G.A.; Jamiolkowski, R.M.; Cleveland, D.W.; Cheeseman, I.M.; Black, B.E. Centromeres are maintained by fastening CENP-A to DNA and directing an arginine anchor-dependent nucleosome transition. Nature Communications, 2017, 8, 15775. doi: 10.1038/ncomms15775
  6. Nemudraya, A.; Kuligina, E.; Ilyichev, A.; Fomin, A.; Stepanov, G.; Savelyeva, A.; Koval, O.; Richter, V. Selection of antitumor displayed peptides for the specific delivery of the anticancer drug lactaptin. Oncology Letters, 2016, 12(6), 4547–4555. doi: 10.3892/ol.2016.5266
  7. Bruckman, M.A.; Czapar, A.E.; VanMeter, A.; Randolph, L.N.; Steinmetz, N.F. Tobacco mosaic virus-based protein nanoparticles and nanorods for chemotherapy delivery targeting breast cancer. Journal of Controlled Release, 2016, 231, 103–113. doi: 10.1016/j.jconrel.2016.02.045
  8. Shebl, B., Menke, D.E.; Pennella, M.; Poudyal, R.R.; Burke, D.H.; Cornish, P.V. Preparation of ribosomes for smFRET studies: A simplified approach. Archives of Biochemistry and Biophysics, 2016, 603, 118–130. doi: 10.1016/j.abb.2016.05.010

Sulfo-Cyanine5.5 azide

  1. Gu, W.; Bobrin, V.A.; Chen, S.-P.R.; Wang, Z.; Schoning, J.P.; Gu, Y.; Chen, W.; Chen, M.; Jia, Z.; Monteiro, M.J. Biodistribution of PNIPAM-Coated Nanostructures Synthesized by the TDMT Method. Biomacromolecules, in press. doi: 10.1021/acs.biomac.8b01196

Sulfo-Cyanine5.5 активированный эфир

  1. Kwon, Y.-D.; Oh, J.-M.; La, M.T.; Chung, H.-J.; Lee, S.J.; Chun, S.; Lee, S.-H.; Jeong, B.-H.; Kim, H.-K. Synthesis and Evaluation of Multifunctional Fluorescent Inhibitors with Synergistic Interaction of PSMA and Hypoxia for Prostate Cancer. Bioconjugate Chemistry, 2019, 30(1), 90–100. doi: 10.1021/acs.bioconjchem.8b00767
  2. Liu, Y.; Wang, Z.; Li, X.; Ma, X.; Wang, S.; Kang, F.; Yang, W.; Ma, W.; Wang, J. Near-infrared Fluorescent Peptides with High Tumor Selectivity: Novel Probes for Image-Guided Surgical Resection of Orthotopic Glioma. Molecular Pharmaceutics, 2019, 16(1), 108–117. doi: 10.1021/acs.molpharmaceut.8b00888
  3. Jasinski, D.L.; Yin, H.; Li, Z.; Guo, P. The Hydrophobic Effect from Conjugated Chemicals or Drugs on in Vivo Biodistribution of RNA Nanoparticles. Human Gene Therapy, 2018, 29(1), 77–86. doi: 10.1089/hum.2017.054
  4. Park, S.; Shevlin, E.; Vedvyas, Y.; Zaman, M.; Park, S.; Hsu, Y.-M.S.; Min, I.M.; Jin, M.M. Micromolar affinity CAR T cells to ICAM-1 achieves rapid tumor elimination while avoiding systemic toxicity. Scientific Reports, 2017, 7, 14366. doi: 10.1038/s41598-017-14749-3
  5. Zhang, C.; Zhao, X.; Guo, S.; Lin, T.; Guo, H. Highly effective photothermal chemotherapy with pH-responsive polymer-coated drug-loaded melanin-like nanoparticles. International Journal of Nanomedicine, 2017, 12, 1827–1840. doi: 10.2147/ijn.s130539
  6. Duan, X.; Li, H.; Zhou, J.; Zhou, Q.; Oldham, K.R.; Wang, T.D. Visualizing epithelial expression of EGFR in vivo with distal scanning side-viewing confocal endomicroscope. Scientific Reports, 2016, 6, 37315. doi: 10.1038/srep37315
  7. Zhou, Q.; Li, Z.; Zhou, J.; Joshi, B.P.; Li, G.; Duan, X.; Kuick, R.; Owens, S.R.; Wang, T.D. In vivo photoacoustic tomography of EGFR overexpressed in hepatocellular carcinoma mouse xenograft. Photoacoustics, 2016, 4(2), 43–54. doi: 10.1016/j.pacs.2016.04.001
  8. Abolmaali, S.; Tamaddon, A.; Kamali-Sarvestani, E.; Ashraf, M.; Dinarvand, R. Stealth Nanogels of Histinylated Poly Ethyleneimine for Sustained Delivery of Methotrexate in Collagen-Induced Arthritis Model. Pharmaceutical Research, 2015, 32(10), 3309–3323. doi: 10.1007/s11095-015-1708-0

Sulfo-Cyanine5.5 амин

  1. Malinovskaya, Y.; Melnikov, P.; Baklaushev, V.; Gabashvili, A.; Osipova, N.; Mantrov, S.; Ermolenko, Y.; Maksimenko, O.; Gorshkova, M.; Balabanyan, V.; Kreuter, J.; Gelperina, S. Delivery of doxorubicin-loaded PLGA nanoparticles into U87 human glioblastoma cells. International Journal of Pharmaceutics, 2017, 524(1–2), 77–90. doi: 10.1016/j.ijpharm.2017.03.049

Sulfo-Cyanine7 активированный эфир

  1. Bykov, Y.; Cohen, N.; Gabrielli, N.; Manenschijn, H.; Welsch, S.; Chlanda, P.; Kukulski, W.; Patil, K.R.R.; Schuldiner, M.; Briggs, J.A.G. Multiplexed electron microscopy by fluorescent barcoding allows screening for ultrastructural phenotype. bioRxiv. doi: 10.1101/515841
  2. Song, J.Y.; Larson, N.R.; Thati, S.; Torres-Vazquez, I.; Martinez-Rivera, N.; Subelzu-Aispuru, N.J.; Leon, M.A.; Rosa-Molinar, E.; Schöneich, C.; Middaugh, C.R.; Berkland, C.J. Glatiramer acetate persists at the injection site and draining lymph nodes via electrostatically-induced aggregation. Journal of Controlled Release, 2019, 293, 36–47. doi: 10.1016/j.jconrel.2018.11.007
  3. Ishihara, J.; Ishihara, A.; Potin, L.; Hosseinchi, P.; Fukunaga, K.; Damo, M.; Gajewski, T.F.; Swartz, M.A.; Hubbell, J.A. Improving Efficacy and Safety of Agonistic Anti-CD40 Antibody Through Extracellular Matrix Affinity. Molecular Cancer Therapeutics, 2018, 17(11), 2399–2411. doi: 10.1158/1535-7163.MCT-18-0091
  4. Henderson, L.; Neumann, O.; Kaffes, C.; Zhang, R.; Marangoni, V.; Ravoori, M.K.; Kundra, V.; Bankson, J.; Nordlander, P.; Halas, N.J. Routes to Potentially Safer T1 Magnetic Resonance Imaging Contrast in a Compact Plasmonic Nanoparticle with Enhanced Fluorescence. ACS Nano, 2018, 12(8), 8214–8223. doi: 10.1021/acsnano.8b03368
  5. Bhatnagar, S.; Verma, K.D.; Hu, Y.; Khera, E.; Priluck, A.; Smith, D.E.; Thurber, G.M. Oral Administration and Detection of a Near-Infrared Molecular Imaging Agent in an Orthotopic Mouse Model for Breast Cancer Screening. Molecular Pharmaceutics, 2018, 15(5), 1746–1754. doi: 10.1021/acs.molpharmaceut.7b00994
  6. Gaspar, I.; Hövelmann, F.; Chamiolo, J.; Ephrussi, A.; Seitz, O. Quantitative mRNA Imaging with Dual Channel qFIT Probes to Monitor Distribution and Degree of Hybridization. ACS Chemical Biology, 2018, 13(3), 742–749. doi: 10.1021/acschembio.7b01007
  7. Liu, Z.; Wang, S.; Li, W.; Tian, Y. Bioimaging and Biosensing of Ferrous Ion in Neurons and HepG2 Cells Upon Oxidative Stress. Analytical Chemistry, 2018, 90(4), 2816–2825. doi: 10.1021/acs.analchem.7b04934
  8. Das, S.; Haedicke, K.; Grimm, J. Cerenkov-activated sticky tag for in vivo fluorescence imaging. Journal of Nuclear Medicine, 2018, 59(1), 58–65. doi: 10.2967/jnumed.117.198549
  9. Timin, A.S.; Muslimov, A.R.; Lepik, K.V.; Epifanovskaya, O.S:; Shakirova, A.I.; Mock, U.; Riecken, K.; Okilova, M.V.; Sergeev, V.S.; Afanasyev, B.V.; Fehse, B.; Sukhorukov, G.B. Efficient gene editing via non-viral delivery of CRISPR-Cas9 system using polymeric and hybrid microcarriers. Nanomedicine: Nanotechnology, Biology, and Medicine, 2018, 14(1), 97–108. doi: 10.1016/j.nano.2017.09.001
  10. Huang, Y.; Zhou, J.; Hakamivala, A.; Wu, J.; Hong, Y.; Borrelli, J.; Tang, L. An optical probe for detecting chondrocyte apoptosis in response to mechanical injury. Scientific Reports, 2017, 7, 10906. doi: 10.1038/s41598-017-10653-y
  11. Nakhaei, E.; Kim, C.W.; Funamoto, D.; Sato, H.; Nakamura, Y.; Kishimura, A.; Mori, T.; Katayama, Y. Design of a ligand for cancer imaging with long blood circulation and an enhanced accumulation ability in tumors. MedChemComm, 2017, 8(6), 1190–1195. doi: 10.1039/c7md00102a
  12. Iyisan, B.; Kluge, J.; Formanek, P.; Voit, B.; Appelhans, D. Multifunctional and Dual-Responsive Polymersomes as Robust Nanocontainers: Design, Formation by Sequential Post-Conjugations, and pH-Controlled Drug Release. Chemistry of Materials, 2016, 28(5), 1513–1525. doi: 10.1021/acs.chemmater.5b05016
  13. Saita, M.; Kaneko, J.; Sato, T.; Takahashi, S.; Takahashi, S.W.; Kawamata, R.; Sakurai, T.; Lee, M.-C.; Hamada, N.; Kimoto, K.; Nagasaki, Y. Novel antioxidative nanotherapeutics in a rat periodontitis model: Reactive oxygen species scavenging by redox injectable gel suppresses alveolar bone resorption. Biomaterials, 2016, 76, 292–301. doi: 10.1016/j.biomaterials.2015.10.077
  14. Subedi, M.; Minn, I.; Chen, J.; Kim, Y.; Ok, K.; Jung, Y.W.; Pomper, M.G.; Byun, Y. Design, synthesis and biological evaluation of PSMA/hepsin-targeted heterobivalent ligands. European Journal of Medicinal Chemistry, 2016, 118, 208–218. doi: 10.1016/j.ejmech.2016.04.033
  15. Cilliers, C.; Liao, J.; Atangcho, L.; Thurber, G.M. Residualization Rates of Near-Infrared Dyes for the Rational Design of Molecular Imaging Agents. Molecular Imaging and Biology, 2015, 17(6), 757–762. doi: 10.1007/s11307-015-0851-7
  16. Terekhov, S., Smirnov, I.; Bobik, T.; Shamborant, O.; Zenkova, M.; Chernolovskaya, E.; Gladkikh, D.; Murashev, A.; Dyachenko, I.; Palikov, V.; Palikova, Y.; Knorre, V.; Belogurov Jr, A.; Ponomarenko, N.; Blackburn, G.M.; Masson, P.; Gabibov, A. A novel expression cassette delivers efficient production of exclusively tetrameric human butyrylcholinesterase with improved pharmacokinetics for protection against organophosphate poisoning. Biochimie, 2015, 118, 51–59. doi: 10.1016/j.biochi.2015.07.028
  17. Mahoney, D.; Owens, E.A.; Fan, C.; Hsiang, J.-C.; Henary, M.; Dickson, R.M. Tailoring Cyanine Dark States for Improved Optically Modulated Fluorescence Recovery. The Journal of Physical Chemistry B, 2015, 119(13), 4637–4643. doi: 10.1021/acs.jpcb.5b00777
  18. Zhang, X.-N.; Zhang, C.-G.; Zhu, Q.-L.; Zhou, Y.; Liu, Y.; Chen, W.-L.; Yang, S.-D. Zhou, X.-F. Zhu, A.-J.; Zhang, X.-N.; Jin, Y. N-Succinyl-chitosan nanoparticles coupled with low-density lipoprotein for targeted osthole-loaded delivery to low-density lipoprotein receptor-rich tumors. International Journal of Nanomedicine, 2014, 9, 2919–2932. doi: 10.2147/ijn.s59799
  19. Terekhov, S.S.; Smirnov, I.V.; Shamborant, O.G.; Zenkova, M.A.; Chernolovskaya, E.L.; Gladkikh, D.V.; Murashev, A.N.; Dyachenko, I.A.; Knorre, V.D.; Belogurov, A.A.; Ponomarenko, N.A.; Deyev, S.M.; Vlasov, V.V.; Gabibov, A.G. Excessive Labeling Technique Provides a Highly Sensitive Fluorescent Probe for Real-time Monitoring of Biodegradation of Biopolymer Pharmaceuticals in vivo. Acta Naturae, 2014, 6(4), 54–59
  20. Ayala-Orozco, C.; Liu, J.G.; Knight, M.W.; Wang, Y.; Day, J.K.; Nordlander, P.; Halas, N.J. Fluorescence Enhancement of Molecules Inside a Gold Nanomatryoshka. Nano Letters, 2014, 14(5), 2926-2933. doi: 10.1021/nl501027j

Sulfo-Cyanine7 амин

  1. Guo, X.; Zou, C.-L.; Jung, H.; Gong, Z.; Bruch, A.; Jiang, L.; Tang, H.X. Efficient Generation of a Near-visible Frequency Comb via Cherenkov-like Radiation from a Kerr Microcomb. Physical Review Applied, 2018, 10(1), 014012. doi: 10.1103/PhysRevApplied.10.014012
  2. Tabe, H.; Sukenobe, K.; Kondo, T.; Sakurai, A.; Maruo, M.; Shimauchi, A.; Hirano, M.; Uno, S.-N.; Kamiya, M.; Urano, Y.; Matsushita, M.; Fujiyoshi, S. Cryogenic Fluorescence Localization Microscopy of Spectrally Selected Individual FRET Pairs in a Water Matrix. The Journal of Physical Chemistry B, 2018, 122(27), 6906–6911. doi: 10.1021/acs.jpcb.8b03977
  3. Miragoli, M.; Ceriotti, P.; Iafisco, M.; Vacchiano, M.; Salvarani, N.; Alogna, A.; Carullo, P.; Ramirez-Rodríguez, G.B.; Patrício, T.; Esposti, L.D.; Rossi, F.; Ravanetti, F.; Pinelli, S.; Alinovi, R.; Erreni, M.; Rossi, S.; Condorelli, G.; Post, H.; Tampieri, A.; Catalucci, D. Inhalation of peptide-loaded nanoparticles improves heart failure. Science Translational Medicine, 2018, 10(424), eaan6205. doi: 10.1126/scitranslmed.aan6205
  4. Park, H.-K.; Lee, S.J.; Oh, J.-S.; Lee, S.-G.; Jeong, Y.-I.; Lee, H.C. Smart Nanoparticles Based on Hyaluronic Acid for Redox-Responsive and CD44 Receptor-Mediated Targeting of Tumor. Nanoscale Research Letters, 2015, 10(1), 981. doi: 10.1186/s11671-015-0981-5

Sulfo-Cyanine7 карбоновая кислота

  1. Luthman, A.S. Wide-Field fHSI with a Linescan SRDA. In: Spectrally Resolved Detector Arrays for Multiplexed Biomedical Fluorescence Imaging (Springer Thesis), 2018, 51–85. doi: 10.1007/978-3-319-98255-7_3
  2. Luthman, A.S.; Dumitru, S.; Quiros-Gonzalez, I.; Joseph, J.; Bohndiek, S.E. Fluorescence hyperspectral imaging (fHSI) using a spectrally resolved detector array. Journal of Biophotonics, 2017, 10(6–7), 840–853. doi: 10.1002/jbio.201600304

Sulfo-Cyanine7.5 карбоновая кислота

  1. Shi, F.; Li, M.; Wu, S.; Yang, F.; Di, W.; Pan, M.; Zhao, F.; Luo, S.; Gu, N.; Dou, J. Enhancing the Anti-Multiple Myeloma Efficiency in a Cancer Stem Cell Xenograft Model by Conjugating the ABCG2 Antibody with Microbubbles for a Targeted Delivery of Ultrasound Mediated Epirubicin. Biochemical Pharmacology, 2017, 132, 18–28. doi: 10.1016/j.bcp.2017.02.014

TAMRA азид, 5-изомер

  1. Eelen, G.; Dubois, C.; Cantelmo, A.R.; Goveia, J.; Brüning, U.; DeRan, M.; Jarugumilli, G.; van Rijssel, J.; Saladino, G.; Comitani, F.; Zecchin, A.; Rocha, S.; Chen, R.; Huang, H.; Vandekeere, S.; Kalucka, J.; Lange, C.; Morales-Rodriguez, F.; Cruys, B.; Treps, L.; Ramer, L.; Vinckier, S.; Brepoels, K.; Wyns, S.; Souffreau, J.; Schoonjans, L.; Lamers, W.H.; Wu, Y.; Haustraete, J.; Hofkens, J.; Liekens, S.; Cubbon, R.; Ghesquière, B.; Dewerchin, M.; Gervasio, F.L.; Li, X.; van Buul, J.D.; Wu, X.; Carmeliet, P. Role of glutamine synthetase in angiogenesis beyond glutamine synthesis. Nature, 2018, 561(7721), 63–69. doi: 10.1038/s41586-018-0466-7
  2. Spangler, B.; Dovala, D.; Sawyer, W.S.; Thompson, K.V.; Six, D.A.; Reck, F.; Feng, B.Y. Molecular probes for the determination of sub-cellular compound exposure profiles in Gram-negative bacteria. ACS Infectious Diseases, 2018, 4(9), 1355–1367. doi: 10.1021/acsinfecdis.8b00093
  3. Moynihan, K.D.; Holden, R.L.; Mehta, N.K.; Wang, C.; Karver, M.R.; Dinter, J.; Liang, S.; Abraham, W.; Melo, M.B.; Zhang, A.Q.; Li, N.; Le Gall, S.; Pentelute, B.; Irvine, D.J. Enhancement of peptide vaccine immunogenicity by increasing lymphatic drainage and boosting serum stability. Cancer Immunology Research, 2018, 6(9), 1025–1038. doi: 10.1158/2326-6066.CIR-17-0607
  4. Li, W.; Zhou, Y.; Tang, G.; Wong, N.-K.; Yang, M.; Tan, D.; Xiao, Y. Chemoproteomics Reveals the Anti-proliferative Potential of Parkinson's Disease Kinase Inhibitor LRRK2-IN-1 by Targeting PCNA Protein. Molecular Pharmaceutics, 2018, 15(8), 3252–3259. doi: 10.1021/acs.molpharmaceut.8b00325
  5. Nemmara, V.J.; Subramanian, V.; Muth, A.; Mondal, S.; Salinger, A.J.; Maurais, A.J.; Tilvawala, R.; Weerapana, E.; Thompson, P.R. The Development of Benzimidazole-Based Clickable Probes for the Efficient Labeling of Cellular Protein Arginine Deiminases (PADs). ACS Chemical Biology, 2018, 13(3), 712–722. doi: 10.1021/acschembio.7b00957
  6. Niessen, S.; Dix, M.M.; Barbas, S.; Potter, Z.E.; Lu, S.; Brodsky, O.; Planken, S.; Behenna, D.; Almaden, C.; Gajiwala, K.S.; Ryan, K.; Ferre, R.; Lazear, M.R.; Hayward, M.M.; Kath, J.C.; Cravatt, B.F. Proteome-wide Map of Targets of T790M-EGFR-Directed Covalent Inhibitors. Cell Chemical Biology, 2017, 24(11), 1388–1400.e7. doi: 10.1016/j.chembiol.2017.08.017
  7. Schonhoft, J.D.; Monteiro, C.; Plate, L.; Eisele, Y.S.; Kelly, J.M.; Boland, D.; Parker, C.G.; Cravatt, B.F.; Teruya, S.; Helmke, S.; Maurer, M.; Berk, J.; Sekijima, Y.; Novais, M.; Coelho, T.; Powers, E.T.; Kelly, J.W. Peptide probes detect misfolded transthyretin oligomers in plasma of hereditary amyloidosis patients. Science Translational Medicine, 2017, 9(407), eaam7621. doi: 10.1126/scitranslmed.aam7621
  8. Planken, S.; Behenna, D.C.; Nair, S.K.; Johnson, T.O.; Nagata, A.; Almaden, C.; Bailey, S.; Ballard, T.E.; Bernier, L.; Cheng, H. et al. Discovery of N-((3R, 4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl) amino)-9-methyl-9H-purin-2-yl) pyrrolidine-3-yl) acrylamide (PF-06747775) Through Structure-Based Drug Design; ... Journal of Medicinal Chemistry, 2017, 60(7), 3002–3019. doi: 10.1021/acs.jmedchem.6b01894
  9. Zhou, Y.; Li, W.; Wang, M.; Zhang, X.; Zhang, H.; Tong, X.; Xiao, Y. Competitive profiling of celastrol targets in human cervical cancer HeLa cells via quantitative chemical proteomics. Molecular BioSystems, 2017, 13(1), 83–91. doi: 10.1039/c6mb00691d
  10. Butler, C.R.; Beck, E.M.; Harris, A.R.; Huang, Z.; McAllister, L.A.; Am Ende, C.W.; Fennell, K.F.; Foley, T.L.; Fonseca, K.R.; Hawrylik, S.J.; Johnson, D.S.; Knafels, J.D.; Mente, S.; Noell, S.; Pandit, J.; Phillips, T.B.; Piro, J.R.; Rogers, B.N.; Samad, T.A.; Wang, J.; Wan, S.; Brodney, M.A. Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase. Journal of Medicinal Chemistry, 2017, 60(23), 9860–9873. doi: 10.1021/acs.jmedchem.7b01531
  11. Zuhl, A.M.; Nolan, C.E.; Brodney, M.A.; Niessen, S.; Atchison, K.; Houle, C.; Karanian, D.A.; Ambroise, Cl.; Brulet, J.W.; Beck, E.M.; Doran, S.D.; O'Neill, B.T.; am Ende, C.W.; Chang, C.; Geoghegan, K.F.; West, G.M.; Judkins, J.C.; Hou, X.; Riddell, D.R.; Johnson, D.S. Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of β-secretase inhibitors. Nature communications, 2016, 7, 13042. doi: 10.1038/ncomms13042
  12. Rana, S.; Blowers, E.C.; Tebbe, C.; Contreras, J.I.; Radhakrishnan, P.; Kizhake, S.; Zhou, T.; Rajule, R.N.; Arnst, J.L.; Munkarah, A.R.; Rattan, R.; Natarajan, A. Isatin Derived Spirocyclic Analogues with α-Methylene-γ-butyrolactone as Anticancer Agents: A Structure-Activity Relationship Study. Journal of Medicinal Chemistry, 2016, 59(10), 5121–5127. doi: 10.1021/acs.jmedchem.6b00400
  13. Zhou, Y.; Li, W.; Xiao, Y. Profiling of Multiple Targets of Artemisinin Activated by Hemin in Cancer Cell Proteome. ACS Chemical Biology, 2016, 11(4), 882–888. doi: 10.1021/acschembio.5b01043
  14. Nusshold, C.; Üllen, A.; Kogelnik, N.; Bernhart, E.; Reicher, H.; Plastira, I.; Glasnov, T.; Zangger, K.; Rechberger, G.; Kollroser, M.; Fauler, G.; Wolinski, H.; Weksler, B.B.; Romero, I.A.; Kohlwein, S.D.; Couraud, P.-O.; Malle, E.; Sattler, W. Assessment of electrophile damage in a human brain endothelial cell line utilizing a clickable alkyne analogue of 2-chlorohexadecanal. Free Radical Biology and Medicine, 2016, 90, 59–74. doi: 10.1016/j.freeradbiomed.2015.11.010
  15. Li, W.; Zhou, Y.; Tang, G.; Xiao, Y. Characterization of the Artemisinin Binding Site for Translationally Controlled Tumor Protein (TCTP) by Bioorthogonal Click Chemistry. Bioconjugate Chemistry, 2016, 27(12), 2828–2833. doi: 10.1021/acs.bioconjchem.6b00556
  16. Mahmoodi, M.M.; Rashidian, M.; Zhang, Y.; Distefano, M.D. Application of meta- and para- Phenylenediamine as Enhanced Oxime Ligation Catalysts for Protein Labeling, PEGylation, Immobilization, and Release. Current Protocols in Protein Science, 2015, 79, 15.4.1–15.4.28. doi: 10.1002/0471140864.ps1504s79
  17. Jia, L.; Chisari, M.; Maktabi, M.H.; Sobieski, C.; Zhou, H.; Konopko, A.M.; Martin, B.R.; Mennerick, S.J.; Blumer, K.J. A Mechanism Regulating G Protein-coupled Receptor Signaling That Requires Cycles of Protein Palmitoylation and Depalmitoylation. Journal of Biological Chemistry, 2014, 289(9), 6249–6257. doi: 10.1074/jbc.m113.531475
  18. Zhou, Y.; Guo, T.; Li, X.; Dong, Y.; Galatsis, P.; Johnson, D.S.; Pan, Z. Discovery of selective 2,4-diaminopyrimidine-based photoaffinity probes for glyoxalase I. Medicinal Chemistry Communications, 2014, 5(3), 352–357. doi: 10.1039/c3md00286a
  19. Zhou, Y.; Guo, T.; Tang, G.; Wu, H.; Wong, N.-K.; Pan, Z. Site-Selective Protein Immobilization by Covalent Modification of GST Fusion Proteins. Bioconjugate Chemistry, 2014, 25(11), 1911-1915. doi: 10.1021/bc500347b

TAMRA азид, 6-изомер

  1. Eelen, G.; Dubois, C.; Cantelmo, A.R.; Goveia, J.; Brüning, U.; DeRan, M.; Jarugumilli, G.; van Rijssel, J.; Saladino, G.; Comitani, F.; Zecchin, A.; Rocha, S.; Chen, R.; Huang, H.; Vandekeere, S.; Kalucka, J.; Lange, C.; Morales-Rodriguez, F.; Cruys, B.; Treps, L.; Ramer, L.; Vinckier, S.; Brepoels, K.; Wyns, S.; Souffreau, J.; Schoonjans, L.; Lamers, W.H.; Wu, Y.; Haustraete, J.; Hofkens, J.; Liekens, S.; Cubbon, R.; Ghesquière, B.; Dewerchin, M.; Gervasio, F.L.; Li, X.; van Buul, J.D.; Wu, X.; Carmeliet, P. Role of glutamine synthetase in angiogenesis beyond glutamine synthesis. Nature, 2018, 561(7721), 63–69. doi: 10.1038/s41586-018-0466-7
  2. Li, W.; Zhou, Y.; Tang, G.; Wong, N.-K.; Yang, M.; Tan, D.; Xiao, Y. Chemoproteomics Reveals the Anti-proliferative Potential of Parkinson's Disease Kinase Inhibitor LRRK2-IN-1 by Targeting PCNA Protein. Molecular Pharmaceutics, 2018, 15(8), 3252–3259. doi: 10.1021/acs.molpharmaceut.8b00325
  3. Nemmara, V.J.; Subramanian, V.; Muth, A.; Mondal, S.; Salinger, A.J.; Maurais, A.J.; Tilvawala, R.; Weerapana, E.; Thompson, P.R. The Development of Benzimidazole-Based Clickable Probes for the Efficient Labeling of Cellular Protein Arginine Deiminases (PADs). ACS Chemical Biology, 2018, 13(3), 712–722. doi: 10.1021/acschembio.7b00957
  4. Zhou, Y.; Li, W.; Wang, M.; Zhang, X.; Zhang, H.; Tong, X.; Xiao, Y. Competitive profiling of celastrol targets in human cervical cancer HeLa cells via quantitative chemical proteomics. Molecular BioSystems, 2017, 13(1), 83–91. doi: 10.1039/c6mb00691d
  5. Butler, C.R.; Beck, E.M.; Harris, A.R.; Huang, Z.; McAllister, L.A.; Am Ende, C.W.; Fennell, K.F.; Foley, T.L.; Fonseca, K.R.; Hawrylik, S.J.; Johnson, D.S.; Knafels, J.D.; Mente, S.; Noell, S.; Pandit, J.; Phillips, T.B.; Piro, J.R.; Rogers, B.N.; Samad, T.A.; Wang, J.; Wan, S.; Brodney, M.A. Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase. Journal of Medicinal Chemistry, 2017, 60(23), 9860–9873. doi: 10.1021/acs.jmedchem.7b01531
  6. Zuhl, A.M.; Nolan, C.E.; Brodney, M.A.; Niessen, S.; Atchison, K.; Houle, C.; Karanian, D.A.; Ambroise, Cl.; Brulet, J.W.; Beck, E.M.; Doran, S.D.; O'Neill, B.T.; am Ende, C.W.; Chang, C.; Geoghegan, K.F.; West, G.M.; Judkins, J.C.; Hou, X.; Riddell, D.R.; Johnson, D.S. Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of β-secretase inhibitors. Nature communications, 2016, 7, 13042. doi: 10.1038/ncomms13042
  7. Zhou, Y.; Li, W.; Xiao, Y. Profiling of Multiple Targets of Artemisinin Activated by Hemin in Cancer Cell Proteome. ACS Chemical Biology, 2016, 11(4), 882–888. doi: 10.1021/acschembio.5b01043
  8. Li, W.; Zhou, Y.; Tang, G.; Xiao, Y. Characterization of the Artemisinin Binding Site for Translationally Controlled Tumor Protein (TCTP) by Bioorthogonal Click Chemistry. Bioconjugate Chemistry, 2016, 27(12), 2828–2833. doi: 10.1021/acs.bioconjchem.6b00556
  9. Mahmoodi, M.M.; Rashidian, M.; Zhang, Y.; Distefano, M.D. Application of meta- and para- Phenylenediamine as Enhanced Oxime Ligation Catalysts for Protein Labeling, PEGylation, Immobilization, and Release. Current Protocols in Protein Science, 2015, 79, 15.4.1–15.4.28. doi: 10.1002/0471140864.ps1504s79
  10. Jia, L.; Chisari, M.; Maktabi, M.H.; Sobieski, C.; Zhou, H.; Konopko, A.M.; Martin, B.R.; Mennerick, S.J.; Blumer, K.J. A Mechanism Regulating G Protein-coupled Receptor Signaling That Requires Cycles of Protein Palmitoylation and Depalmitoylation. Journal of Biological Chemistry, 2014, 289(9), 6249–6257. doi: 10.1074/jbc.m113.531475
  11. Zhou, Y.; Guo, T.; Li, X.; Dong, Y.; Galatsis, P.; Johnson, D.S.; Pan, Z. Discovery of selective 2,4-diaminopyrimidine-based photoaffinity probes for glyoxalase I. Medicinal Chemistry Communications, 2014, 5(3), 352–357. doi: 10.1039/c3md00286a

TAMRA алкин, 5-изомер

  1. Rojas-Sánchez, L.; Sokolova, V.; Riebe, S.; Voskuhl, J.; Epple, M. Covalent Surface Functionalization of Calcium Phosphate Nanoparticles with Fluorescent Dyes by Copper-Catalysed and by Strain-Promoted Azide-Alkyne Click Chemistry. ChemNanoMat, in press. doi: 10.1002/cnma.201800509

TAMRA алкин, 6-изомер

  1. Rink, W.M.; Thomas, F. Decoration of Coiled-Coil Peptides with N-Cysteine Peptide Thioesters As Cyclic Peptide Precursors Using Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC) Click Reaction. Organic Letters, 2018, 20(23), 7493–7497. doi: 10.1021/acs.orglett.8b03261

TFA-амино CPG 500

  1. Taskova, M.; Uhd, J.; Miotke, L.; Kubit, M.; Bell, J.; Ji, H.P.; Astakhova, K. Tandem Oligonucleotide Probe Annealing and Elongation To Discriminate Viral Sequence. Analytical Chemistry, 2017, 89(8), 4363–4366. doi: 10.1021/acs.analchem.7b00646

sulfo-Cyanine5 бис- NHS-эфир

  1. Pettersson, J.R.; Lanni, F.; Rule, G.S. Dual lifetimes for complexes between Glutathione-S-transferase (hGSTA1-1) and product-like ligands detected by single-molecule fluorescence imaging. Biochemistry, 2017, 56(31), 4073–4083. doi: 10.1021/acs.biochem.7b00030

Азидомасляной кислоты активированный эфир

  1. Kuznetsov, A.E.; Komarova, N.V.; Kuznetsov, E.V.; Andrianova, M.S.; Grudtsov, V.P.; Rybachek, E.N.; Puchnin, K.V.; Ryazantsev, D.V.; Saurov, A.N. Integration of a field effect transistor-based aptasensor under a hydrophobic membrane for bioelectronic nose applications. Biosensors and Bioelectronics. doi: 10.1016/j.bios.2019.01.013
  2. Kumar, P.; Kuhlmann, F.M.; Chakroborty, S.; Bourgeois, A.L.; Foulke-Abel, J.; Tumala, B.; Vickers, T.J.; Sack, D.A.; DeNearing, B.; Harro, C.D.; Wright, W.S.; Gildersleeve, J.C.; Ciorba, M.A.; Santhanam, S.; Porter, C.K.; Gutierrez, R.L.; Prouty, M.G.; Riddle, M.S.; Polino, A.; Sheikh, A.; Donowitz, M.; Fleckenstein, J.M. Enterotoxigenic Escherichia coli blood group A interactions intensify diarrheal severity. The Journal of Clinical Investigation, 2018, 128(8), 3298–3311. doi: 10.1172/JCI97659
  3. Andrianova, M.; Komarova, N.; Grudtsov, V.; Kuznetsov, E.; Kuznetsov, A. Amplified Detection of the Aptamer-Vanillin Complex with the Use of Bsm DNA Polymerase. Sensors, 2018, 18, 49. doi: 10.3390/s18010049
  4. Kuznetsov, A.; Komarova, N.; Andrianova, M.; Grudtsov, V.; Kuznetsov, E. Aptamer based vanillin sensor using an ion-sensitive field-effect transistor. Microchimica Acta, 2018, 185(1), 3. doi: 10.1007/s00604-017-2586-4
  5. Taskova, M.; Uhd, J.; Miotke, L.; Kubit, M.; Bell, J.; Ji, H.P.; Astakhova, K. Tandem Oligonucleotide Probe Annealing and Elongation To Discriminate Viral Sequence. Analytical Chemistry, 2017, 89(8), 4363–4366. doi: 10.1021/acs.analchem.7b00646
  6. Bu, J.; Pilo, A.L.; McLuckey, S.A. Gas Phase Click Chemistry via Ion/Ion Reactions. International Journal of Mass Spectrometry, 2015, 390, 118–123. doi: 10.1016/j.ijms.2015.05.010
  7. Potapova, I.; Eglin, D.; Laschke, M.W.; Bischoff, M.; Richards, R.G.; Moriarty, T.F. Two-step labeling of Staphylococcus aureus with Lysostaphin-Azide and DIBO-Alexa using click chemistry. Journal of Microbiological Methods, 2013, 92(1), 90-98. doi: 10.1016/j.mimet.2012.11.004

Алкиновый амидит (5'-концевой)

  1. Farzan, V.M.; Kvach, M.V.; Aparin, I.O.; Kireev, D.E.; Prikazchikova, T.A.; Ustinov, A.V.; Shmanai, V.V.; Shipulin, G.A.; Korshun, V.A.; Zatsepin, T.S. Novel homo Yin-Yang probes improve sensitivity in RT-qPCR detection of low copy HIV RNA. Talanta, 2019, 194, 226–232. doi: 10.1016/j.talanta.2018.10.043
  2. Taskova, M.; Uhd, J.; Miotke, L.; Kubit, M.; Bell, J.; Ji, H.P.; Astakhova, K. Tandem Oligonucleotide Probe Annealing and Elongation To Discriminate Viral Sequence. Analytical Chemistry, 2017, 89(8), 4363–4366. doi: 10.1021/acs.analchem.7b00646
  3. Aparin, I.O.; Farzan, V.M.; Veselova, O.A.; Chistov, A.A.; Podkolzin, A.T.; Ustinov, A.V.; Shipulin, G.A.; Formanovsky, A.A.; Korshun, V.A.; Zatsepin, T.S. 1-Phenylethynylpyrene (PEPy) as a novel blue-emitting dye for qPCR assay. Analyst, 2016, 141, 1331–1338. doi: 10.1039/c5an01767j
  4. Astakhova, I.K.; Santhosh Kumar, T.; Campbell, M.A.; Ustinov, A.V.; Korshun, V.A.; Wengel, J. Branched DNA nanostructures efficiently stabilised and monitored by novel pyrene-perylene 2'-alpha-L-amino-LNA FRET pairs. Chemical Communications, 2013, 49(5), 511-511. doi: 10.1039/c2cc37547h

Амино-11-ddUTP

  1. Gaspar, I.; Wippich, F.; Ephrussi, A. Enzymatic production of single molecule FISH and RNA capture probes. RNA, 2017, 23(10), 1582–1591. doi: 10.1261/rna.061184.117

Аскорбиновая кислота

  1. Taskova, M.; Uhd, J.; Miotke, L.; Kubit, M.; Bell, J.; Ji, H.P.; Astakhova, K. Tandem Oligonucleotide Probe Annealing and Elongation To Discriminate Viral Sequence. Analytical Chemistry, 2017, 89(8), 4363–4366. doi: 10.1021/acs.analchem.7b00646
  2. Samuelsen, S.V.; Maity, A.; Nybo, M.; Macaubas, C.; Lønstrup, L.; Balboni, I.M.; Mellins, E.D.; Astakhova, K. Novel Phospholipid-Protein Conjugates Allow Improved Detection of Antibodies in Patients with Autoimmune Diseases. PLoS One, 2016, 11(6), e0156125. doi: 10.1371/journal.pone.0156125
  3. Li, Z.; Liu, Z.; Chen, Z.; Ju, E.; Li, W.; Ren, J.; Qu, X. Bioorthogonal chemistry for selective recognition, separation and killing bacteria over mammalian cells. Chemical Communications, 2016, 52(17), 3482–3485. doi: 10.1039/c5cc10625g
  4. Maity, A.; Macaubas, C.; Mellins, E.; Astakhova, K. Synthesis of Phospholipid-Protein Conjugates as New Antigens for Autoimmune Antibodies. Molecules, 2015, 20(6), 10253–10263. doi: 10.3390/molecules200610253

Биотин PEG3 азид

  1. Wang, E.; Hunter, C.P. SID-1 Functions in Multiple Roles To Support Parental RNAi in Caenorhabditis elegans. Genetics, 2017, 207(2), 547–557. doi: 10.1534/genetics.117.300067
  2. Bruckman, M.A.; Czapar, A.E.; VanMeter, A.; Randolph, L.N.; Steinmetz, N.F. Tobacco mosaic virus-based protein nanoparticles and nanorods for chemotherapy delivery targeting breast cancer. Journal of Controlled Release, 2016, 231, 103–113. doi: 10.1016/j.jconrel.2016.02.045

Биотин алкин

  1. Rink, W.M.; Thomas, F. Decoration of Coiled-Coil Peptides with N-Cysteine Peptide Thioesters As Cyclic Peptide Precursors Using Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC) Click Reaction. Organic Letters, 2018, 20(23), 7493–7497. doi: 10.1021/acs.orglett.8b03261
  2. Cui, X.-Y.; Sun, N.-N.; Xie, X.-N.; Sun, W.-C.; Zhao, Q.; Liu, N. Detection of Newly Synthesized Proteins via Metabolic Incorporation of Non-natural Amino Acid. Chinese Journal of Analytical Chemistry, 2018, 46(11), 1808–1813. doi: 10.1016/s1872-2040(18)61125-9
  3. Ullrich, M.; Liang, V.; Chew, Y.L.; Banister, S.; Song, X.; Zaw, T.; Lam, H.; Berber, S.; Kassiou, M.; Nicholas, H.R. et al. Bio-orthogonal labeling as a tool to visualize and identify newly synthesized proteins in Caenorhabditis elegans. Nature Protocols, 2014, 9(9), 2237-2255. doi: 10.1038/nprot.2014.150

Диметилформамид для мечения

  1. Gu, R.; Oweida, T.; Yingling, Y.G.; Chilkoti, A.; Zauscher, S. Enzymatic synthesis of nucleobase-modified single-stranded DNA offers tunable resistance to nuclease degradation. Biomacromolecules, 2018, 19(8), 3525–3535. doi: 10.1021/acs.biomac.8b00816

Краситель Pico488 для определения концентрации ДНК, 200x раствор в ДМСО

  1. Norred, S.E.; Dabbs, R.M.; Chauhan, G.; Caveney, P.M.; Collier, C.P.; Abel, S.M.; Simpson, M.L. Synergistic interactions between confinement and macromolecular crowding spatially order transcription and translation in cell-free expression. bioRxiv, unrefereed preprint. doi: 10.1101/445544

Кумарин 343 азид

  1. Musiol-Kroll, E.M.; Zubeil, F.; Schafhauser, T.; Härtner, T.; Kulik, A.; McArthur, J.B.; Koryakina, I.; Wohlleben, W.; Grond, S.; Williams, G.J.; Lee, S.Y.; Weber, T. Polyketide bio-derivatization using the promiscuous acyltransferase KirCII. ACS Synthetic Biology, 2017, 6(3), 421–427. doi: 10.1021/acssynbio.6b00341
  2. Teske, N.S.; Voigt, J.; Shastri, V.P. Clickable Degradable Aliphatic Polyesters via Copolymerization with Alkyne Epoxy Esters: Synthesis and Postfunctionalization with Organic Dyes. Journal of the American Chemical Society, 2014, 136(29), 10527-10533. doi: 10.1021/ja505629w

Пентиновой кислоты активированный эфир (STP)

  1. Samuelsen, S.V.; Maity, A.; Nybo, M.; Macaubas, C.; Lønstrup, L.; Balboni, I.M.; Mellins, E.D.; Astakhova, K. Novel Phospholipid-Protein Conjugates Allow Improved Detection of Antibodies in Patients with Autoimmune Diseases. PLoS One, 2016, 11(6), e0156125. doi: 10.1371/journal.pone.0156125
  2. Maity, A.; Macaubas, C.; Mellins, E.; Astakhova, K. Synthesis of Phospholipid-Protein Conjugates as New Antigens for Autoimmune Antibodies. Molecules, 2015, 20(6), 10253–10263. doi: 10.3390/molecules200610253

Перилен азид

  1. Westergaard Mulberg, M.; Taskova, M.; Thomsen, R.P.; Okholm, A.H.; Kjems, J.; Astakhova, K. New Fluorescent Nanoparticles for Ultrasensitive Detection of Nucleic Acids by Optical Methods. Chembiochem, 2017, 18(16), 1599–1603. doi: 10.1002/cbic.201700125
  2. Okholm, A.; Kjems, J.; Astakhova, K. Fluorescence detection of natural RNA using rationally designed "clickable" oligonucleotide probes. RSC Advances, 2014, 4(86), 45653–45656. doi: 10.1039/c4ra07165d

Пирен азид 2

  1. Wanat, P.; Walczak, S.; Wojtczak, B.A.; Nowakowska, M.; Jemielity, J.; Kowalska, J. Ethynyl, 2-Propynyl, and 3-Butynyl C-Phosphonate Analogues of Nucleoside Di- and Triphosphates: Synthesis and Reactivity in CuAAC. Organic Letters, 2015, 17(12), 3062–3065. doi: 10.1021/acs.orglett.5b01346
Товар добавлен. Просмотрите корзину покупок или оформите заказ
Введено некорректное число товаров для добавления.