Список цитирований

Список публикаций, цитирующих продукты Lumiprobe. Публикации можно отсортировать по дате или по продукту.

Сортировка
по дате по продукту

В печати

  1. Feng, X.; Cui, X.; Zhang, L.-S.; Ye, C.; Wang, P.; Zhong, Y.; Zheng, Z.; He, C. Sequencing of N 6 -Methyl-Deoxyadenosine at Single-Base Resolution across the Mammalian Genome. bioRxiv, 2023, preprint. doi: 10.1101/2023.01.16.524325
  2. Soxpollard, N.; Strauss, S.; Jungmann, R.; MacPherson, I. Selection of Antibody-Binding Covalent Aptamers. bioRxiv, 2023, preprint. doi: 10.1101/2023.03.09.530504
  3. Piranej, S.; Zhang, L.; Bazrafshan, A.; Marin, M.; Melikyan, G. B.; Salaita, K. Rolosense: Mechanical Detection of SARS-CoV-2 Using a DNA-Based Motor. bioRxiv, 2023, preprint. doi: 10.1101/2023.02.27.530294
  4. Ayala-Orozco, C.; Galvez-Aranda, D.; Corona, A.; Seminario, J. M.; Rangel, R.; Myers, J. N.; Tour, J. M. Molecular Jackhammers Eradicate Cancer Cells by Vibronic-Driven Action. bioRxiv, 2023, preprint. doi: 10.1101/2023.01.25.525400
  5. Morrison, V. E.; Houpert, M. G.; Trapani, J. B.; Brockman, A. A.; Kingsley, P. J.; Katdare, K. A.; Layden, H. M.; Nguena-Jones, G.; Trevisan, A. J.; Maguire-Zeiss, K. A.; Marnett, L. J.; Bixa, G. J.; Ihrie, R. A.; Carter, B. D. Jedi-1/MEGF12-Mediated Phagocytosis Controls the pro-Neurogenic Properties of Microglia in the Ventricular-Subventricular Zone. bioRxiv, 2023, preprint. doi: 10.1101/2023.03.03.531012
  6. Matthews, M.; Cook, E.; Naguib, N.; Wiesner, U.; Lewis, K. Intravital Imaging of Osteocyte αvβ3 Integrin Dynamics with Locally Injectable Fluorescent Nanoparticles. bioRxiv, 2023, preprint. doi: 10.1101/2023.02.23.529785
  7. Yao, P.; Liu, R.; Broginni, T.; Thunemann, M.; Kleinfeld, D. Guide to the Construction and Use of an Adaptive Optics Two-Photon Microscope with Direct Wavefront Sensing. bioRxiv, 2023, preprint. doi: 10.1101/2023.01.24.525307
  8. Montepietra, D.; Tesei, G.; Martins, J. M.; Kunze, M. B. A.; Best, R. B.; Lindorff-Larsen, K. FRETpredict: A Python Package for FRET Efficiency Predictions Using Rotamer Libraries. bioRxiv, 2023, preprint. doi: 10.1101/2023.01.27.525885
  9. Krasikova, A.; Kulikova, T.; Ramos, J. S. R.; Maslova, A. Assignment of the Somatic A/B Compartments to Chromatin Domains in Giant Transcriptionally Active Lampbrush Chromosomes. bioRxiv, 2023. doi: 10.1101/2023.03.14.532542
  10. Musicò, A.; Zenatelli, R.; Romano, M.; Zendrini, A.; Alacqua, S.; Tassoni, S.; Paolini, L.; Urbinati, C.; Rusnati, M.; Bergese, P.; Pomarico, G.; Radeghieri, A. Assessing the Effect of Protein Corona Formation in the Process of EV Surface Engineering. ChemRxiv, 2023, preprint. doi: 10.26434/chemrxiv-2023-rh5s8
  11. Knudsen, E. B.; Zappitelli, K.; Brown, J.; Reeder, J.; Smith, K. S.; Rostov, M.; Choi, J.; Rochford, A.; Slager, N.; Miura, S. K.; Rodgers, K.; Reed, A.; Lewis Israeli, Y. R.; Shiraga, S.; Seo, K. J.; Wolin, C.; Dawson, P.; Eltaeb, M.; Dasgupta, A.; Rothman, M.; Yoon, E.; Chong, P.; Charles, S.; Stewart, J. M.; Silva, R. A.; Kim, T.; Kong, Y.; Mardinly, A. R.; Hodak, M. A Thin-Film Optogenetic Visual Prosthesis. bioRxiv, 2023, preprint. doi: 10.1101/2023.01.31.526482
  12. Chadda, R.; Lee, T.; Sandal, P.; Mahoney-Kruszka, R.; Robertson, J. L. A Thermodynamic Analysis of CLC Transporter Dimerization in Lipid Bilayers. bioRxiv, 2023, preprint. doi: 10.1101/2023.03.14.532678
  13. Martin-Alonso, C.; Tabrizi, S.; Xiong, K.; Blewett, T.; Patel, S.; An, Z.; Sridhar, S.; Bekdemir, A.; Shea, D.; Amini, A. P.; Wang, S.-T.; Kirkpatrick, J.; Rhoades, J.; Golub, T. R.; Love, J. C.; Adalsteinsson, V. A.; Bhatia, S. N. A Nanoparticle Priming Agent Reduces Cellular Uptake of Cell-Free DNA and Enhances the Sensitivity of Liquid Biopsies. bioRxiv, 2023, preprint. doi: 10.1101/2023.01.13.524003
  14. Song, X.; Jin, J.; Yin, H.; Wang, T.; Zong, H.; Wang, F.; Liu, J.; Huang, X.; Wang, B.; Chai, C.; Li, Z.; Liu, D.; Wang, X.; Song, N. Trichoderma Viride F7 Improves Peanut Performance While Remedying Cadmium-Contaminated Soil with Microplastics. Pedosphere, 2023. doi: 10.1016/j.pedsph.2023.06.010
  15. Jaiswal, M.; Tran, T. T.; Guo, J.; Zhou, M.; Kunda, S.; Guo, Z.; Fanucci, G. Spin-Labeling Insights into How Chemical Fixation Impacts Glycan Organization on Cells. Research Square, 2023, preprint. doi: doi.org/10.21203/rs.3.rs-3039983/v1
  16. Kislova, A. V.; Zheglo, D.; Pozhitnova, V. O.; Sviridov, P. S.; Gadzhieva, E. P.; Voronina, E. S. Replication Stress Causes Delayed Mitotic Entry and Chromosome 12 Fragility at the ANKS1B Large Neuronal Gene in Human Induced Pluripotent Stem Cells. Research Square, 2023, preprint. doi: 10.21203/rs.3.rs-2781849/v1
  17. Izzo, A.; Akol, I.; Villarreal, A.; Garcia-Miralles, M.; Bovio, P.; Heidrich, S.; Vogel, T. Nucleophosmin 1 Cooperates with the Methyltransferase DOT1L to Regulate H3K79me2 Levels and DNA Satellites Expression at Peri-Nucleolar Heterochromatin. Research Square, 2023, preprint. doi: 10.21203/rs.3.rs-2745386/v1
  18. Ehrman, R. N.; Brohlin, O. R.; Wijesundara, Y. H.; Kumari, S.; Trashi, I.; Trashi, O.; Howlett, T. S.; Herbert, F. C.; Raja, A.; Koirala, S.; Tran, N.; Al-Kharji, N. M.; Hagge, L. M.; Gassensmith, J. A Scalable Synthesis of Adjuvanting Antigen Depots Based on Met-al-Organic Frameworks. ChemRxiv, 2023, preprint. doi: 10.26434/chemrxiv-2023-gtl30
  19. Wang, L.; Qiao, S.; Xia, R.; Liu, Y.; Hu, Y.; Wu, Y.; Zhou, J.; Liang, G.; Tian, T.; Cao, L. Mesenchymal Stromal Cell–Derived Magnetic Nanovesicles for Enhanced Skin Retention and Hair Follicle Growth. Cytotherapy, 2023. doi: 10.1016/j.jcyt.2023.07.001

2023

  1. Kerr, M. D.; McBride, D. A.; Johnson, W. T.; Chumber, A. K.; Najibi, A. J.; Seo, B. R.; Stafford, A. G.; Scadden, D. T.; Mooney, D. J.; Shah, N. J. Immune-Responsive Biodegradable Scaffolds for Enhancing Neutrophil Regeneration. Bioengineering & Translational Medicine, 2023, 8(1), e10309. doi: 10.1002/btm2.10309
  2. Toti, K. S.; Campbell, R. G.; Lee, H.; Salmaso, V.; Suresh, R. R.; Gao, Z.-G.; Jacobson, K. A. Fluorescent A2A and A3 Adenosine Receptor Antagonists as Flow Cytometry Probes. Purinergic Signalling, 2023, 19(3), 565–578. doi: 10.1007/s11302-022-09873-3
  3. Shesterikova, E. M.; Bondarenko, V. S.; Volkova, P. Yu. Differential Gene Expression in Chronically Irradiated Herbaceous Species from the Chernobyl Exclusion Zone. International Journal of Radiation Biology, 2023, 99(2), 229–237. doi: 10.1080/09553002.2022.2087927
  4. Gabold, B.; Adams, F.; Brameyer, S.; Jung, K.; Ried, C. L.; Merdan, T.; Merkel, O. M. Transferrin-Modified Chitosan Nanoparticles for Targeted Nose-to-Brain Delivery of Proteins. Drug Deliv. and Transl. Res., 2023, 13(3), 822–838. doi: 10.1007/s13346-022-01245-z
  5. Bär, S. I.; Schleser, S. W.; Oberhuber, N.; Herrmann, A.; Schlotte, L.; Weber, S. E.; Schobert, R. Trans-[Bis(Benzimidazol-2-Ylidene)Dichlorido]Platinum(II) Complexes with Peculiar Modes of Action and Activity against Cisplatin-Resistant Cancer Cells. Journal of Inorganic Biochemistry, 2023, 238, 112028. doi: 10.1016/j.jinorgbio.2022.112028
  6. Loukas, I.; Simeoni, F.; Milan, M.; Inglese, P.; Patel, H.; Goldstone, R.; East, P.; Strohbuecker, S.; Mitter, R.; Talsania, B.; Tang, W.; Ratcliffe, C. D. H.; Sahai, E.; Shahrezaei, V.; Scaffidi, P. Selective Advantage of Epigenetically Disrupted Cancer Cells via Phenotypic Inertia. Cancer Cell, 2023, 41(1), 70-87.e14. doi: 10.1016/j.ccell.2022.10.002
  7. Repellin, M.; Carton, F.; Boschi, F.; Galiè, M.; Perduca, M.; Calderan, L.; Jacquier, A.; Carras, J.; Schaeffer, L.; Briançon, S.; Lollo, G.; Malatesta, M. Repurposing Pentamidine Using Hyaluronic Acid-Based Nanocarriers for Skeletal Muscle Treatment in Myotonic Dystrophy. Nanomedicine: Nanotechnology, Biology and Medicine, 2023, 47, 102623. doi: 10.1016/j.nano.2022.102623
  8. Pershina, A. G.; Demin, A. M.; Perekucha, N. A.; Brikunova, O. Y.; Efimova, L. V.; Nevskaya, K. V.; Vakhrushev, A. V.; Zgoda, V. G.; Uimin, M. A.; Minin, A. S.; Malkeyeva, D.; Kiseleva, E.; Zima, A. P.; Krasnov, V. P.; Ogorodova, L. M. Peptide Ligands on the PEGylated Nanoparticle Surface and Human Serum Composition Are Key Factors for the Interaction between Immune Cells and Nanoparticles. Colloids and Surfaces B: Biointerfaces, 2023, 221, 112981. doi: 10.1016/j.colsurfb.2022.112981
  9. Nie, Q.; Li, C.; Wang, Y.; Hu, Y.; Pu, W.; Zhang, Q.; Cai, J.; Lin, Y.; Li, G.; Wang, C.; Li, L.; Dou, Y.; Zhang, J. Pathologically Triggered in Situ Aggregation of Nanoparticles for Inflammation-Targeting Amplification and Therapeutic Potentiation. Acta Pharmaceutica Sinica B, 2023, 13(1), 390–409. doi: 10.1016/j.apsb.2022.07.013
  10. Hebels, E. R.; Bindt, F.; Walther, J.; van Geijn, M.; Weterings, J.; Hu, Q.; Colombo, C.; Liskamp, R.; Rijcken, C.; Hennink, W. E.; Vermonden, T. Orthogonal Covalent Entrapment of Cargo into Biodegradable Polymeric Micelles via Native Chemical Ligation. Biomacromolecules, 2023, 24(10), 4385–4396. doi: 10.1021/acs.biomac.2c00865
  11. Robertson, N.; Sempere, L.; Kenyon, E.; Mallet, C.; Smith, K.; Hix, J.; Halim, A.; Fan, J.; Moore, A. Omniparticle Contrast Agent for Multimodal Imaging: Synthesis and Characterization in an Animal Model. Mol Imaging Biol, 2023, 25(2), 401–412. doi: 10.1007/s11307-022-01770-w
  12. Chen, L.; Xu, N.; Wang, P.; Zhu, H.; Zhang, Z.; Yang, Z.; Zhang, W.; Guo, H.; Lin, J. Nanoalbumin–Prodrug Conjugates Prepared via a Thiolation-and-Conjugation Method Improve Cancer Chemotherapy and Immune Checkpoint Blockade Therapy by Promoting CD8+ T-Cell Infiltration. Bioengineering & Translational Medicine, 2023, 8(1), e10377. doi: 10.1002/btm2.10377
  13. Sokolov, A. V.; Isakova-Sivak, I. N.; Mezhenskaya, D. A.; Kostevich, V. A.; Gorbunov, N. P.; Elizarova, A. Yu.; Matyushenko, V. A.; Berson, Yu. M.; Grudinina, N. A.; Kolmakov, N. N.; Zabrodskaya, Y. A.; Komlev, A. S.; Semak, I. V.; Budevich, A. I.; Rudenko, L. G.; Vasilyev, V. B. Molecular Mimicry of the Receptor-Binding Domain of the SARS-CoV-2 Spike Protein: From the Interaction of Spike-Specific Antibodies with Transferrin and Lactoferrin to the Antiviral Effects of Human Recombinant Lactoferrin. Biometals, 2023, 36(3), 437–462. doi: 10.1007/s10534-022-00458-6
  14. Strada, A.; Frigerio, R.; Bergamaschi, G.; Gagni, P.; Cretich, M.; Gori, A. Membrane-Sensing Peptides for Extracellular Vesicle Analysis. Peptide Microarrays: Methods and Protocols, 2023, 249–257. doi: 10.1007/978-1-0716-2732-7_18
  15. Li, H.; Zhong, Y.; Wang, S.; Zha, M.; Gu, W.; Liu, G.; Wang, B.; Yu, Z.; Wang, Y.; Li, K.; Yin, Y.; Mu, J.; Chen, X. In Vivo Bioorthogonal Labeling of Rare-Earth Doped Nanoparticles for Improved NIR-II Tumor Imaging by Extracellular Vesicle-Mediated Targeting. Nano Res., 2023, 16(2), 2895–2904. doi: 10.1007/s12274-022-5033-8
  16. Husser, C.; Baudrey, S.; Ryckelynck, M. High-Throughput Development and Optimization of RNA-Based Fluorogenic Biosensors of Small Molecules Using Droplet-Based Microfluidics. Nucleic Acid Aptamers. Methods in Molecular Biology, 2023, 2570, 243–269. doi: 10.1007/978-1-0716-2695-5_19
  17. Adachi, J.; Oda, H.; Fukushima, T.; Lestari, B.; Kimura, H.; Sugai, H.; Shiraki, K.; Hamaguchi, R.; Sato, K.; Kinbara, K. Dense and Acidic Organelle-Targeted Visualization in Living Cells: Application of Viscosity-Responsive Fluorescence Utilizing Restricted Access to Minimum Energy Conical Intersection. Anal. Chem., 2023, 95(12), 5196–5204. doi: 10.1021/acs.analchem.2c04133
  18. Cadavid, J. L.; Latour, S.; Nowlan, F.; Co, I. L.; Landon-Brace, N.; Wouters, B. G.; Grünwald, B. T.; Nitz, M.; Jackson, H. W.; McGuigan, A. P. An Engineered Paper-Based 3D Coculture Model of Pancreatic Cancer to Study the Impact of Tissue Architecture and Microenvironmental Gradients on Cell Phenotype. Advanced Healthcare Materials, 2023, 12(14), 2201846. doi: 10.1002/adhm.202201846
  19. Ko, H. S.; Yang, D. H.; Kim, A.; Wie, J. H.; Kim, S. H.; Jeong, G.-J.; Hyun, H.; Shin, J. C.; Chun, H. J. Visible Light-Curable Methacrylated Glycol Chitosan Hydrogel Patches for Prenatal Closure of Fetal Myelomeningocele. Carbohydrate Polymers, 2023, 311, 120620. doi: 10.1016/j.carbpol.2023.120620
  20. Babi, M.; Williams, A.; Reid, M.; Grandfield, K.; Bassim, N. D.; Moran-Mirabal, J. M. Unraveling the Supramolecular Structure and Nanoscale Dislocations of Bacterial Cellulose Ribbons Using Correlative Super-Resolution Light and Electron Microscopy. Biomacromolecules, 2023, 24(1), 258–268. doi: 10.1021/acs.biomac.2c01108
  21. Khrustaleva, L.; Nzeha, M.; Ermolaev, A.; Nikitina, E.; Romanov, V. Two-Step Identification of N-, S-, R- and T-Cytoplasm Types in Onion Breeding Lines Using High-Resolution Melting (HRM)-Based Markers. International Journal of Molecular Sciences, 2023, 24(2), 1605. doi: 10.3390/ijms24021605
  22. Zhang, B.; Pan, H.; Chen, Z.; Yin, T.; Zheng, M.; Cai, L. Twin-Bioengine Self-Adaptive Micro/Nanorobots Using Enzyme Actuation and Macrophage Relay for Gastrointestinal Inflammation Therapy. Sci. Adv., 2023, 9(8), eadc8978. doi: 10.1126/sciadv.adc8978
  23. Uvyn, A.; Tonneaux, C.; Fossépré, M.; Ouvrier-Buffet, A.; De Geest, B. G.; Surin, M. Towards a Rational Design of Antibody-Recruiting Molecules through a Computational Microscopy View of Their Interactions with the Target Antibody. Chemistry – A European Journal, 2023, 29(30), e202300474. doi: 10.1002/chem.202300474
  24. McGregor, L. A.; Zhu, B.; Goetz, A. M.; Sczepanski, J. T. Thymine DNA Glycosylase Is an RNA-Binding Protein with High Selectivity for G-Rich Sequences. Journal of Biological Chemistry, 2023, 299(4), 104590. doi: 10.1016/j.jbc.2023.104590
  25. Li, W.; Liu, Z.; Wang, P.; Di, R.; Wang, X.; Liu, Y.; Chu, M. The Transcription Factor RUNX1 Affects the Maturation of Porcine Oocytes via the BMP15/TGF-β Signaling Pathway. International Journal of Biological Macromolecules, 2023, 238, 124026. doi: 10.1016/j.ijbiomac.2023.124026
  26. Shushunova, N. A.; Mayorova, O. A.; Prikhozhdenko, E. S.; Goryacheva, O. A.; Kulikov, O. A.; Plastun, V. O.; Gusliakova, O. I.; Muslimov, A. R.; Inozemtseva, O. A.; Pyataev, N. A.; Shirokov, A. A.; Gorin, D. A.; Sukhorukov, G. B.; Sindeeva, O. A. Targeted Therapy for Glomerulonephritis Using Arterial Delivery of Encapsulated Etanercept. International Journal of Molecular Sciences, 2023, 24(3), 2784. doi: 10.3390/ijms24032784
  27. Yodsanit, N.; Shirasu, T.; Huang, Y.; Yin, L.; Islam, Z. H.; Gregg, A. C.; Riccio, A. M.; Tang, R.; Kent, E. W.; Wang, Y.; Xie, R.; Zhao, Y.; Ye, M.; Zhu, J.; Huang, Y.; Hoyt, N.; Zhang, M.; Hossack, J. A.; Salmon, M.; Kent, K. C.; Guo, L.-W.; Gong, S.; Wang, B. Targeted PERK Inhibition with Biomimetic Nanoclusters Confers Preventative and Interventional Benefits to Elastase-Induced Abdominal Aortic Aneurysms. Bioactive Materials, 2023, 26, 52–63. doi: 10.1016/j.bioactmat.2023.02.009
  28. Bariana, M.; Zhang, B.; Sun, J.; Wang, W.; Wang, J.; Cassella, E.; Myint, F.; Anuncio, S. A.; Ouk, S.; Liou, H.-C.; Tan, M.; Wang, H.; Zakrzewski, J. L. Targeted Lymphoma Therapy Using a Gold Nanoframework-Based Drug Delivery System. ACS Appl. Mater. Interfaces, 2023, 15(5), 6312–6325. doi: 10.1021/acsami.2c17214
  29. Lee, J.-R.; Sim, W.-S.; Park, H.-J.; Park, B.-W.; Joung, Y. K. Targeted Delivery of Apoptotic Cell-Derived Nanovesicles Prevents Cardiac Remodeling and Attenuates Cardiac Function Exacerbation. Advanced Functional Materials, 2023, 33(23), 2210864. doi: 10.1002/adfm.202210864
  30. Bashore, C.; Prakash, S.; Johnson, M. C.; Conrad, R. J.; Kekessie, I. A.; Scales, S. J.; Ishisoko, N.; Kleinheinz, T.; Liu, P. S.; Popovych, N.; Wecksler, A. T.; Zhou, L.; Tam, C.; Zilberleyb, I.; Srinivasan, R.; Blake, R. A.; Song, A.; Staben, S. T.; Zhang, Y.; Arnott, D.; Fairbrother, W. J.; Foster, S. A.; Wertz, I. E.; Ciferri, C.; Dueber, E. C. Targeted Degradation via Direct 26S Proteasome Recruitment. Nature Chemical Biology, 2023, 19(1), 55–63. doi: 10.1038/s41589-022-01218-w
  31. Zashikhina, N.; Gladnev, S.; Sharoyko, V.; Korzhikov-Vlakh, V.; Korzhikova-Vlakh, E.; Tennikova, T. Synthesis and Characterization of Nanoparticle-Based Dexamethasone-Polypeptide Conjugates as Potential Intravitreal Delivery Systems. International Journal of Molecular Sciences, 2023, 24(4), 3702. doi: 10.3390/ijms24043702
  32. Anderson, C. F.; Wang, Q.; Stern, D.; Leonard, E. K.; Sun, B.; Fergie, K. J.; Choi, C.; Spangler, J. B.; Villano, J.; Pekosz, A.; Brayton, C. F.; Jia, H.; Cui, H. Supramolecular Filaments for Concurrent ACE2 Docking and Enzymatic Activity Silencing Enable Coronavirus Capture and Infection Prevention. Matter, 2023, 6(2), 583–604. doi: 10.1016/j.matt.2022.11.027
  33. Reddi, R. N.; Rogel, A.; Gabizon, R.; Rawale, D. G.; Harish, B.; Marom, S.; Tivon, B.; Arbel, Y. S.; Gurwicz, N.; Oren, R.; David, K.; Liu, J.; Duberstein, S.; Itkin, M.; Malitsky, S.; Barr, H.; Katz, B.-Z.; Herishanu, Y.; Shachar, I.; Shulman, Z.; London, N. Sulfamate Acetamides as Self-Immolative Electrophiles for Covalent Ligand-Directed Release Chemistry. J. Am. Chem. Soc, 2023, 145(6), 3346–3360. doi: 10.1021/jacs.2c08853
  34. Marin, M. A.; Gleichman, A. J.; Brumm, A. J.; Carmichael, S. T. Subcortical White Matter Stroke in the Mouse: Inducing Injury and Tracking Cellular Proliferation. Neural Repair: Methods and Protocols, 2023, 2616, 13–20. doi: 10.1007/978-1-0716-2926-0_2
  35. Chhonker, Y. S.; Wojtynek, N. E.; Agrawal, P.; Mohs, A. M.; Murry, D. J. A Simple and Sensitive LC-MS/MS for Quantitation of ICG in Rat Plasma: Application to a Pre-Clinical Pharmacokinetic Study. Separations, 2023, 10(2), 66. doi: 10.3390/separations10020066
  36. Mao, X.; Ye, R. One-Pot Synthesis of Enzyme and Antibody/CaHPO4 Nanoflowers for Magnetic Chemiluminescence Immunoassay of Salmonella Enteritidis. Sensors, 2023, 23(5), 2779. doi: 10.3390/s23052779
  37. Psotta, C.; Chaturvedi, V.; Gonzalez-Martinez, J. F.; Sotres, J.; Falk, M. Portable Prussian Blue-Based Sensor for Bacterial Detection in Urine. Sensors, 2023, 23(1), 388. doi: 10.3390/s23010388
  38. Gerasimova, N. S.; Pestov, N. A.; Studitsky, V. M. Role of Histone Tails and Single Strand DNA Breaks in Nucleosomal Arrest of RNA Polymerase. International Journal of Molecular Sciences, 2023, 24(3), 2295. doi: 10.3390/ijms24032295
  39. Lai, C.; Zhang, B.; Li, D.; Tan, X.; Luo, B.; Shen, J.; Li, L.; Shao, J. Rational Design of a Minimum Nanoplatform for Maximizing Therapeutic Potency: Three Birds with One Stone. Journal of Colloid and Interface Science, 2023, 635, 441–455. doi: 10.1016/j.jcis.2022.12.157
  40. Sharma, A. K.; Fitieh, A. M.; Locke, A. J.; Ali, J. Y. H.; Ismail, I. H. Quantification of Protein Enrichment at Site-Specific DNA Double-Strand Breaks by Chromatin Immunoprecipitation in Cultured Human Cells. STAR Protocols, 2023, 4(1), 101917. doi: 10.1016/j.xpro.2022.101917
  41. Liu, Y.; Jia, Z.; Ma, L.; Wang, D. Pyrophosphorylated-Cholesterol-Modified Bone-Targeting Liposome Formulation Procedure. Liposomes: Methods and Protocols, 2023, 2622, 207–220. doi: 10.1007/978-1-0716-2954-3_18
  42. Cui, J.; Zhang, C.; Liu, H.; Yang, L.; Liu, X.; Zhang, J.; Zhou, Y.; Zhang, J.; Yan, X. Pulmonary Delivery of Recombinant Human Bleomycin Hydrolase Using Mannose-Modified Hierarchically Porous UiO-66 for Preventing Bleomycin-Induced Pulmonary Fibrosis. ACS Appl. Mater. Interfaces, 2023, 15(9), 11520–11535. doi: 10.1021/acsami.2c20479
  43. Wlodarczyk, M. T.; Dragulska, S. A.; Chen, Y.; Poursharifi, M.; Acosta Santiago, M.; Martignetti, J. A.; Mieszawska, A. J. Pt(II)-PLGA Hybrid in a PH-Responsive Nanoparticle System Targeting Ovarian Cancer. Pharmaceutics, 2023, 15(2), 607. doi: 10.3390/pharmaceutics15020607
  44. Sabuncu, S.; Montoya Mira, J.; Quentel, A.; Gomes, M. M.; Civitci, F.; Fischer, J. M.; Yildirim, A. Protein-Coated Biodegradable Gas-Stabilizing Nanoparticles for Cancer Therapy and Diagnosis Using Focused Ultrasound. Advanced Materials Interfaces, 2023, 10(2), 2201543. doi: 10.1002/admi.202201543
  45. Dhara, S. P.; Udvadia, A. J. Profiling Dynamic Changes in DNA Accessibility During Axon Regeneration After Optic Nerve Crush in Adult Zebrafish. Axon Regeneration: Methods and Protocols, 2023, 2636, 323–341. doi: 10.1007/978-1-0716-3012-9_18
  46. Pizzi, D.; Humphries, J.; Morrow, J. P.; Mahmoud, A. M.; Fletcher, N. L.; Sonderegger, S. E.; Bell, C. A.; Thurecht, K. J.; Kempe, K. Probing the Biocompatibility and Immune Cell Association of Chiral, Water-Soluble, Bottlebrush Poly(2-Oxazoline)s. Biomacromolecules, 2023, 24(1), 246–257. doi: 10.1021/acs.biomac.2c01105
  47. Barclay, M. S.; Chowdhury, A. U.; Biaggne, A.; Huff, J. S.; Wright, N. D.; Davis, P. H.; Li, L.; Knowlton, W. B.; Yurke, B.; Pensack, R. D.; Turner, D. B. Probing DNA Structural Heterogeneity by Identifying Conformational Subensembles of a Bicovalently Bound Cyanine Dye. The Journal of Chemical Physics, 2023, 158(3), 035101. doi: 10.1063/5.0131795
  48. Ruan, Z.; Li, S.; Grigoropoulos, A.; Amiri, H.; Hilburg, S. L.; Chen, H.; Jayapurna, I.; Jiang, T.; Gu, Z.; Alexander-Katz, A.; Bustamante, C.; Huang, H.; Xu, T. Population-Based Heteropolymer Design to Mimic Protein Mixtures. Nature, 2023, 615(7951), 251–258. doi: 10.1038/s41586-022-05675-0
  49. Guo, H.; Xu, W.; Nomoto, T.; Kanamori, K.; Voon, Y. M.; Honda, Y.; Yamada, N.; Takemoto, H.; Matsui, M.; Nishiyama, N. Polymeric Ligands Comprising Sulfur-Containing Amino Acids for Targeting Tumor-Associated Amino Acid Transporters. Biomaterials, 2023, 293, 121987. doi: 10.1016/j.biomaterials.2022.121987
  50. Song, Y.; He, Y.; Rong, L.; Wang, Z.; Ma, Y.; Zhang, N.; Wang, B. “Platelet-Coated Bullets” Biomimetic Nanoparticles to Ameliorate Experimental Colitis by Targeting Endothelial Cells. Biomaterials Advances, 2023, 148, 213378. doi: 10.1016/j.bioadv.2023.213378
  51. Meiers, J.; Dastbaz, J.; Adam, S.; Rasheed, S.; Kirsch, S. H.; Meiser, P.; Gross, P.; Müller, R.; Titz, A. Pineapple Lectin AcmJRL Binds SARS-CoV-2 Spike Protein in a Carbohydrate-Dependent Fashion**. ChemBioChem, 2023, 24(3), e202200463. doi: 10.1002/cbic.202200463
  52. Nizamov, T. R.; Iliasov, A. R.; Vodopyanov, S. S.; Kozhina, I. V.; Bordyuzhin, I. G.; Zhukov, D. G.; Ivanova, A. V.; Permyakova, E. S.; Mogilnikov, P. S.; Vishnevskiy, D. A.; Shchetinin, I. V.; Abakumov, M. A.; Savchenko, A. G. Study of Cytotoxicity and Internalization of Redox-Responsive Iron Oxide Nanoparticles on PC-3 and 4T1 Cancer Cell Lines. Pharmaceutics, 2023, 15(1), 127. doi: 10.3390/pharmaceutics15010127
  53. Roussel, S.; Grenier, P.; Chénard, V.; Bertrand, N. Dual-Labelled Nanoparticles Inform on the Stability of Fluorescent Labels In Vivo. Pharmaceutics 2023, 15 (3), 769., 2023, 15(3), 769. doi: 10.3390/pharmaceutics15030769
  54. Khramtsov, Y. V.; Ulasov, A. V.; Rosenkranz, A. A.; Slastnikova, T. A.; Lupanova, T. N.; Georgiev, G. P.; Sobolev, A. S. An Approach to Evaluate the Effective Cytoplasmic Concentration of Bioactive Agents Interacting with a Selected Intracellular Target Protein. Pharmaceutics, 2023, 15(2), v. doi: 10.3390/pharmaceutics15020324
  55. Asker, M.; Krieger, J.-P.; Liles, A.; Tinsley, I. C.; Borner, T.; Maric, I.; Doebley, S.; Furst, C. D.; Börchers, S.; Longo, F.; Bhat, Y. R.; De Jonghe, B. C.; Hayes, M. R.; Doyle, R. P.; Skibicka, K. P. Peripherally Restricted Oxytocin Is Sufficient to Reduce Food Intake and Motivation, While CNS Entry Is Required for Locomotor and Taste Avoidance Effects. Diabetes, Obesity and Metabolism, 2023, 25(3), 856–877. doi: 10.1111/dom.14937
  56. Meng, P.; Shao, Y.; Xiong, Y.; Zhang, L.; Bao, H.; Lu, H. Peptide- and Protein-Level Combined Strategy for Analyzing Newly Synthesized Proteins by Integrating Tandem Orthogonal Proteolysis with Cleavable Bioorthogonal Tagging. Anal. Chem., 2023, 95(2), 628–637. doi: 10.1021/acs.analchem.2c01537
  57. Nikitin, M. P. Non-Complementary Strand Commutation as a Fundamental Alternative for Information Processing by DNA and Gene Regulation. Nature Chemistry, 2023, 15(1), 70-82. doi: 10.1038/s41557-022-01111-y
  58. Song, Q.-X.; Liu, N.-N.; Liu, Z.-X.; Zhang, Y.-Z.; Rety, S.; Hou, X.-M.; Xi, X.-G. Nonstructural N- and C-Tails of Dbp2 Confer the Protein Full Helicase Activities. Journal of Biological Chemistry, 2023, 299(5), 104592. doi: 10.1016/j.jbc.2023.104592
  59. Garafutdinov, R. R.; Burkhanova, G. F.; Maksimov, I. V.; Sakhabutdinova, A. R. New Method for MicroRNA Detection Based on Multimerization. Analytical Biochemistry, 2023, 664, 115049. doi: 10.1016/j.ab.2023.115049
  60. Cai, J.; Liu, L.; Qin, Z.; Liu, S.; Wang, Y.; Chen, Z.; Yao, Y.; Zheng, L.; Zhao, J.; Gao, M. Natural Morin-Based Metal Organic Framework Nanoenzymes Modulate Articular Cavity Microenvironment to Alleviate Osteoarthritis. Research, 2023, 6, 0068. doi: 10.34133/research.0068
  61. Liu, B.; Kong, Y.; Alimi, O. A.; Kuss, M. A.; Tu, H.; Hu, W.; Rafay, A.; Vikas, K.; Shi, W.; Lerner, M.; Berry, W. L.; Li, Y.; Carlson, M. A.; Duan, B. Multifunctional Microgel-Based Cream Hydrogels for Postoperative Abdominal Adhesion Prevention. ACS Nano, 2023, 17(4), 3847–3864. doi: 10.1021/acsnano.2c12104
  62. Mitin, D. E.; Chubarov, A. S. Fluorinated Human Serum Albumin as Potential 19F Magnetic Resonance Imaging Probe. Molecules, 2023, 28(4), 1695. doi: 10.3390/molecules28041695.
  63. Kropacheva, N. O.; Golyshkin, A. A.; Vorobyeva, M. A.; Meschaninova, M. I. Convenient Solid-Phase Attachment of Small-Molecule Ligands to Oligonucleotides via a Biodegradable Acid-Labile P-N-Bond. Molecules, 2023, 28(4), 1904. doi: 10.3390/molecules28041904
  64. Sapozhnikova, K. A.; Gulyak, E. L.; Misyurin, V. A.; Simonova, M. A.; Ryabukhina, E. V.; Alexeeva, A. V.; Tikhonova, N. A.; Lyzhko, N. A.; Popova, G. P.; Misyurin, A. V.; Ustinov, A. V.; Korshun, V. A.; Alferova, V. A.; Ryazantsev, D. Y.; Brylev, V. A. Branched Linkers for Site-Specific Fluorescent Labeling of Antibodies. Molecules, 2023, 28(1), 425. doi: 10.3390/molecules28010425
  65. Pattadar, D.; Zheng, L.; Robb, A. J.; Beery, D.; Yang, W.; Hanson, K.; Saavedra, S. S. Molecular Orientation of −PO3H2 and −COOH Functionalized Dyes on TiO2, Al2O3, ZrO2, and ITO: A Comparative Study. J. Phys. Chem. C, 2023, 127(5), 2705–2715. doi: 10.1021/acs.jpcc.2c08632
  66. Rybkin, I.; Pinyaev, S.; Sindeeva, O.; German, S. V.; Koblar, M.; Pyataev, N.; Čeh, M.; Gorin, D.; Sukhorukov, G.; Lapanje, A. Modification of Bacterial Cells for in Vivo Remotely Guided Systems. Frontiers in Bioengineering and Biotechnology, 2023, 10, 1070851. doi: 10.3389/fbioe.2022.1070851
  67. Dong, B.; Qiu, Y.; Liu, Z.; Huang, J.; Wang, Z.; Tu, Q.; Zhou, Z.; He, J.; Wang, Y.; Liu, X.; Zhang, J.; Shuai, X.; Tao, J.; Xia, W. Manipulating Bioactivities of Endothelial Progenitor Cell-Derived Exosomes for Promoting Angiogenesis in Ischemic Vascular Diseases. Nano Today, 2023, 48, 101758. doi: 10.1016/j.nantod.2023.101758
  68. Loppinet, E.; Besser, H. A.; Sewa, A. S.; Yang, F.-C.; Jabri, B.; Khosla, C. LRP-1 Links Post-Translational Modifications to Efficient Presentation of Celiac Disease-Specific T Cell Antigens. Cell Chemical Biology, 2023, 30(1), 55-68.e10. doi: 10.1016/j.chembiol.2022.12.002
  69. Zeng, Z.; Hou, W.; Hu, Z.; Liu, L.; Liu, Z.; Shi, Y.; Li, M.; Chen, Y. Long-Acting Insulin-Zwitterionic Polymer Conjugate Mitigates Hypoglycemia. Chemistry – A European Journal, 2023, 29(12), e202203460. doi: 10.1002/chem.202203460
  70. Liao, T.-W.; Huang, L.; Wilson, T. J.; Ganser, L. R.; Lilley, D. M. J.; Ha, T. Linking Folding Dynamics and Function of SAM/SAH Riboswitches at the Single Molecule Level. Nucleic Acids Research, 2023, 51(17), 8957–8969. doi: 10.1093/nar/gkad633
  71. Barberio, A. E.; Smith, S. G.; Pires, I. S.; Iyer, S.; Reinhardt, F.; Melo, M. B.; Suh, H.; Weinberg, R. A.; Irvine, D. J.; Hammond, P. T. Layer-by-Layer Interleukin-12 Nanoparticles Drive a Safe and Effective Response in Ovarian Tumors. Bioengineering & Translational Medicine, 2023, 8(2), e10453. doi: 10.1002/btm2.10453
  72. Janiszewski, T.; Kołt, S.; Ciastoń, I.; Vizovisek, M.; Poręba, M.; Turk, B.; Drąg, M.; Kozieł, J.; Kasperkiewicz, P. Investigation of Osteoclast Cathepsin K Activity in Osteoclastogenesis and Bone Loss Using a Set of Chemical Reagents. Cell Chemical Biology, 2023, 30(2), 159-174.e8. doi: 10.1016/j.chembiol.2023.01.001
  73. Bao, X.; Qian, K.; Xu, M.; Chen, Y.; Wang, H.; Pan, T.; Wang, Z.; Yao, P.; Lin, L. Intestinal Epithelium Penetration of Liraglutide via Cholic Acid Pre-Complexation and Zein/Rhamnolipids Nanocomposite Delivery. Journal of Nanobiotechnology, 2023, 21(1), 16. doi: 10.1186/s12951-022-01743-9
  74. Son, S.; Nam, J.; Kim, A. S.; Ahn, J.; Park, K. S.; Phoo, M. T.; Sherren, B.; Zou, W.; Lee, S.-H.; Farokhzad, O. C.; Shi, J.; Moon, J. J. Induction of T-Helper-17-Cell-Mediated Anti-Tumour Immunity by Pathogen-Mimicking Polymer Nanoparticles. Nature Biomedical Engineering, 2023, 7(1), 72–84. doi: 10.1038/s41551-022-00973-4
  75. Cho, H.; Jeon, S. I.; Shim, M. K.; Ahn, C.-H.; Kim, K. In Situ Albumin-Binding and Esterase-Specifically Cleaved BRD4-Degrading PROTAC for Targeted Cancer Therapy. Biomaterials, 2023, 295, 122038. doi: 10.1016/j.biomaterials.2023.122038
  76. Pizarek, J. A.; Fischer, N. G.; Aparicio, C. Immunomodulatory IL-23 Receptor Antagonist Peptide Nanocoatings for Implant Soft Tissue Healing. Dental Materials, 2023, 39(2), 204–216. doi: 10.1016/j.dental.2023.01.001
  77. Wang, Y.-J.; Li, L.; Yu, J.; Hu, H.-Y.; Liu, Z.-X.; Jiang, W.-J.; Xu, W.; Guo, X.-P.; Wang, F.-S.; Sheng, J.-Z. Imaging of Escherichia Coli K5 and Glycosaminoglycan Precursors via Targeted Metabolic Labeling of Capsular Polysaccharides in Bacteria. Sci. Adv., 2023, 9(7), eade4770. doi: 10.1126/sciadv.ade4770
  78. Kalinovsky, D. V.; Kholodenko, I. V.; Kibardin, A. V.; Doronin, I. I.; Svirshchevskaya, E. V.; Ryazantsev, D. Y.; Konovalova, M. V.; Rozov, F. N.; Larin, S. S.; Deyev, S. M.; Kholodenko, R. V. Minibody-Based and ScFv-Based Antibody Fragment-Drug Conjugates Selectively Eliminate GD2-Positive Tumor Cells. International Journal of Molecular Sciences, 2023, 24(2), 1239. doi: 10.3390/ijms24021239
  79. Malinovskaya, J.; Salami, R.; Valikhov, M.; Vadekhina, V.; Semyonkin, A.; Semkina, A.; Abakumov, M.; Harel, Y.; Levy, E.; Levin, T.; Persky, R.; Chekhonin, V.; Lellouche, J.-P.; Melnikov, P.; Gelperina, S. Supermagnetic Human Serum Albumin (HSA) Nanoparticles and PLGA-Based Doxorubicin Nanoformulation: A Duet for Selective Nanotherapy. International Journal of Molecular Sciences, 2023, 24(1), 627. doi: 10.3390/ijms24010627
  80. Drozdov, A. S.; Komarova, K. S.; Mochalova, E. N.; Komedchikova, E. N.; Shipunova, V. O.; Nikitin, M. P. Fluorescent Magnetic Nanoparticles for Bioimaging through Biomimetic Surface Modification. International Journal of Molecular Sciences, 2023, 24(1), 134. doi: 10.3390/ijms24010134
  81. Miltner, N.; Kalló, G.; Csősz, É.; Miczi, M.; Nagy, T.; Mahdi, M.; Mótyán, J. A.; Tőzsér, J. Identification of SARS-CoV-2 Main Protease (Mpro) Cleavage Sites Using Two-Dimensional Electrophoresis and In Silico Cleavage Site Prediction. International Journal of Molecular Sciences, 2023, 24(4), 3236. doi: 10.3390/ijms24043236
  82. Sandberg, E.; Piguet, J.; Liu, H.; Widengren, J. Combined Fluorescence Fluctuation and Spectrofluorometric Measurements Reveal a Red-Shifted, Near-IR Emissive Photo-Isomerized Form of Cyanine 5. International Journal of Molecular Sciences, 2023, 24(3), 1990. doi: 10.3390/ijms24031990
  83. Van Baelen, A.-C.; Iturrioz, X.; Chaigneau, M.; Kessler, P.; Llorens-Cortes, C.; Servent, D.; Gilles, N.; Robin, P. Characterization of the First Animal Toxin Acting as an Antagonist on AT1 Receptor. International Journal of Molecular Sciences, 2023, 24(3), 2330. doi: 10.3390/ijms24032330
  84. Novopashina, D. S.; Dymova, M. A.; Davydova, A. S.; Meschaninova, M. I.; Malysheva, D. O.; Kuligina, E. V.; Richter, V. A.; Kolesnikov, I. A.; Taskaev, S. Y.; Vorobyeva, M. A. Aptamers for Addressed Boron Delivery in BNCT: Effect of Boron Cluster Attachment Site on Functional Activity. International Journal of Molecular Sciences, 2023, 24(1), 306. doi: 10.3390/ijms24010306
  85. Sapozhnikova, K. A.; Gulyak, E. L.; Brylev, V. A.; Misyurin, V. A.; Oreshkov, S. D.; Alexeeva, A. V.; Ryazantsev, D. Y.; Simonova, M. A.; Ryabukhina, E. V.; Popova, G. P.; Tikhonova, N. A.; Lyzhko, N. A.; Barmashov, A. E.; Misyurin, A. V.; Ustinov, A. V.; Alferova, V. A.; Korshun, V. A. Aminooxy Click Modification of a Periodate-Oxidized Immunoglobulin G: A General Approach to Antibody–Drug Conjugates with Dye-Mediated Expeditious Stoichiometry Control. International Journal of Molecular Sciences, 2023, 24(6), 5134. doi: 10.3390/ijms24065134
  86. Dong, N.; Liu, Z.; He, H.; Lu, Y.; Qi, J.; Wu, W. “Hook&Loop” Multivalent Interactions Based on Disk-Shaped Nanoparticles Strengthen Active Targeting. Journal of Controlled Release, 2023, 354, 279–293. doi: 10.1016/j.jconrel.2023.01.022
  87. Long, Y.; Guo, J.; Chen, J.; Sun, J.; Wang, H.; Peng, X.; Wang, Z.; Lai, W.; Liu, N.; Shu, L.; Chen, L.; Shi, Y.; Xiao, D.; Liu, S.; Tao, Y. GPR162 Activates STING Dependent DNA Damage Pathway as a Novel Tumor Suppressor and Radiation Sensitizer. Signal Transduction and Targeted Therapy, 2023, 8(1), 48. doi: 10.1038/s41392-022-01224-3
  88. Modrzycka, S.; Kołt, S.; Adams, T. E.; Potoczek, S.; Huntington, J. A.; Kasperkiewicz, P.; Drąg, M. Fluorescent Activity-Based Probe To Image and Inhibit Factor XIa Activity in Human Plasma. J. Med. Chem., 2023, 66(6), 3785–3797. doi: 10.1021/acs.jmedchem.2c00845
  89. McMahon, N. P.; Jones, J. A.; Anderson, A. N.; Dietz, M. S.; Wong, M. H.; Gibbs, S. L. Flexible Cyclic Immunofluorescence (CyCIF) Using Oligonucleotide Barcoded Antibodies. Cancers, 2023, 15(3), 827. doi: 10.3390/cancers15030827
  90. Han, S.; da Costa Marques, R.; Simon, J.; Kaltbeitzel, A.; Koynov, K.; Landfester, K.; Mailänder, V.; Lieberwirth, I. Endosomal Sorting Results in a Selective Separation of the Protein Corona from Nanoparticles. Nature Communications, 2023, 14(1), 295. doi: 10.1038/s41467-023-35902-9
  91. Saud, K. T.; Xu, J.; Wilkanowicz, S.; He, Y.; Moon, J. J.; Solomon, M. J. Electrosprayed Microparticles from Inulin and Poly(Vinyl) Alcohol for Colon Targeted Delivery of Prebiotics. Food Hydrocolloids, 2023, 140, 108625. doi: 10.1016/j.foodhyd.2023.108625.
  92. Schraven, S.; Rosenhain, S.; Brueck, R.; Wiechmann, T. M.; Pola, R.; Etrych, T.; Lederle, W.; Lammers, T.; Gremse, F.; Kiessling, F. Dye Labeling for Optical Imaging Biases Drug Carriers’ Biodistribution and Tumor Uptake. Nanomedicine: Nanotechnology, Biology and Medicine, 2023, 48, 102650. doi: 10.1016/j.nano.2023.102650
  93. Al-Nakashli, R.; Raveendran, R.; Khine, Y. Y.; Cao, C.; McKay, S.; Lu, H.; Stenzel, M. H. Drug-Loading Content Influences Cellular Uptake of Polymer-Coated Nanocellulose. Mol. Pharmaceutics, 2023, 20(4), 2017–2028. doi: 10.1021/acs.molpharmaceut.2c00997
  94. Yi, G.; Sung, Y.; Kim, C.; Ra, J. S.; Hirakawa, H.; Kato, T. A.; Fujimori, A.; Kim, H.; Takata, K. DNA Polymerase θ-Mediated Repair of High LET Radiation-Induced Complex DNA Double-Strand Breaks. Nucleic Acids Research, 2023, 51(5), 2257–2269. doi: 10.1093/nar/gkad076
  95. Chetverikov, P. E.; Craemer, C.; Gankevich, V. D.; Kremenetskaya, M. V.; Kuzmin, I. V.; Zhuk, A. S. Endoparasitic Gall Mites: Two New Novophytoptus Species (Eriophyoidea, Phytoptidae) from Southern African Sedges (Cyperaceae, Carex) and New Hypotheses on the Phylogeny of Novophytoptines. Diversity, 2023, 15(3), 416;. doi: 10.3390/d15030416
  96. Joo, S.-H.; Kim, J.; Hong, J.; Fakhraei Lahiji, S.; Kim, Y.-H. Dissolvable Self-Locking Microneedle Patches Integrated with Immunomodulators for Cancer Immunotherapy. Advanced Materials, 2023, 35(10), 2209966. doi: 10.1002/adma.202209966
  97. Zhang, H.; Guo, J.; Wang, Z.; Wang, N.; Feng, N.; Zhang, Y. Diethylene Glycol Monoethyl Ether-Mediated Nanostructured Lipid Carriers Enhance Trans -Ferulic Acid Delivery by Caco-2 Cells Superior to Solid Lipid Nanoparticles. Acta Pharmaceutica, 2023, 73(1), 133–143. doi: 10.2478/acph-2023-0009
  98. Jiang, Y.; Lyu, Z.; Ralahy, B.; Liu, J.; Roussel, T.; Ding, L.; Tang, J.; Kosta, A.; Giorgio, S.; Tomasini, R.; Liang, X.-J.; Dusetti, N.; Iovanna, J.; Peng, L. Dendrimer Nanosystems for Adaptive Tumor-Assisted Drug Delivery via Extracellular Vesicle Hijacking. Proc. Natl. Acad. Sci. U.S.A., 2023, 120(7), e2215308120. doi: 10.1073/pnas.2215308120
  99. Strasser, P.; Montsch, B.; Weiss, S.; Sami, H.; Kugler, C.; Hager, S.; Schueffl, H.; Mader, R.; Brüggemann, O.; Kowol, C. R.; Ogris, M.; Heffeter, P.; Teasdale, I. Degradable Bottlebrush Polypeptides and the Impact of Their Architecture on Cell Uptake, Pharmacokinetics, and Biodistribution In Vivo. Small, 2023, 19(22), 2300767. doi: 10.1002/smll.202300767
  100. Gao, W.; He, J.; Chen, L.; Meng, X.; Ma, Y.; Cheng, L.; Tu, K.; Gao, X.; Liu, C.; Zhang, M.; Fan, K.; Pang, D.-W.; Yan, X. Deciphering the Catalytic Mechanism of Superoxide Dismutase Activity of Carbon Dot Nanozyme. Nature Communications, 2023, 14(1), 160. doi: 10.1038/s41467-023-35828-2
  101. Lin, W.; Gandhi, S.; Bhattarai, P.; Kasa, K.; Kizil, C.; Zhang, Y. Combining High Throughput Array Synthesis and Growth Algorithm to Discover TNF-α Binders with New Structures and Properties. European Journal of Medicinal Chemistry, 2023, 248, 115078. doi: 10.1016/j.ejmech.2022.115078
  102. Eljack, S.; Allard-Vannier, E.; Misericordia, Y.; Hervé-Aubert, K.; Aubrey, N.; Chourpa, I.; Faggad, A.; David, S. Combination of Nanovectorized SiRNA Directed against Survivin with Doxorubicin for Efficient Anti-Cancer Activity in HER2+ Breast Cancer Cells. Pharmaceutics, 2023, 14(11), 2537. doi: 10.3390/pharmaceutics14112537
  103. Catania, G.; Rodella, G.; Vanvarenberg, K.; Préat, V.; Malfanti, A. Combination of Hyaluronic Acid Conjugates with Immunogenic Cell Death Inducer and CpG for Glioblastoma Local Chemo-Immunotherapy Elicits an Immune Response and Induces Long-Term Survival. Biomaterials, 2023, 294, 122006. doi: 10.1016/j.biomaterials.2023.122006
  104. Bagdanoff, J. T.; Smith, T. M.; Allan, M.; O’Donnell, P.; Nguyen, Z.; Moore, E. A.; Baird, J.; Wang, S.; Subramanian, V.; Tigani, B.; Nettleton, D. O.; Monovich, L. G.; Lewis, I.; Flyer, A. N.; Granda, B.; Blankenship, J. W.; Barnes-Seeman, D.; Clairmont, K. B. Clearance of Plasma PCSK9 via the Asialoglycoprotein Receptor Mediated by Heterobifunctional Ligands. Cell Chemical Biology, 2023, 30(1), 97-109.e9. doi: 10.1016/j.chembiol.2022.12.003
  105. Sousa De Almeida, M.; Roshanfekr, A.; Balog, S.; Petri-Fink, A.; Rothen-Rutishauser, B. Cellular Uptake of Silica Particles Influences EGFR Signaling Pathway and Is Affected in Response to EGF. IJN, 2023, 18, 1047–1061. doi: 10.2147/IJN.S388557
  106. Neupane, Y. R.; Handral, H. K.; Alkaff, S. A.; Chng, W. H.; Venkatesan, G.; Huang, C.; Lee, C. K.; Wang, J.-W.; Sriram, G.; Dienzo, R. A.; Lu, W. F.; Ali, Y.; Czarny, B.; Pastorin, G. Cell-Derived Nanovesicles from Mesenchymal Stem Cells as Extracellular Vesicle-Mimetics in Wound Healing. Acta Pharmaceutica Sinica B, 2023, 13(5), 1887–1902. doi: 10.1016/j.apsb.2022.10.022
  107. Komkova, M. A.; Shavokshina, V. A.; Zarochintsev, A. A.; Melnik, D. M.; Aparin, I. O.; Zatsepin, T. S.; Karyakin, A. A. Catalytically Synthesized Prussian Blue Nanozymes as Labels for Electrochemical DNA/RNA Sensors. Talanta, 2023, 257, 124337. doi: 10.1016/j.talanta.2023.124337
  108. Chen, H.; Li, Y.; Li, L.; Yang, Z.; Wen, Z.; Liu, L.; Liu, H.; Chen, Y. Carrier-Free Subunit Nanovaccine Amplifies Immune Responses against Tumors and Viral Infections. Acta Biomaterialia, 2023, 158, 525–534. doi: 10.1016/j.actbio.2022.12.042
  109. Bunce, C.; Barske, L.; Zhang, G.; Capel, B. Biased Precursor Ingression Underlies the Center-to-Pole Pattern of Male Sex Determination in Mouse. Development, 2023, 150(5), dev201060. doi: 10.1242/dev.201060
  110. Moiseeva, N.; Eroshenko, D.; Laletina, L.; Rybalkina, E.; Susova, O.; Karamysheva, A.; Tolmacheva, I.; Nazarov, M.; Grishko, V. The Molecular Mechanisms of Oleanane Aldehyde-β-Enone Cytotoxicity against Doxorubicin-Resistant Cancer Cells. Biology, 2023, 12(3), 415. doi: 10.3390/biology12030415
  111. Du, G.; Zhao, L.; Zheng, Y.; Belfetmi, A.; Cai, T.; Xu, B.; Heyninck, K.; Van Den Heede, K.; Buyse, M.-A.; Fontana, P.; Bowman, M.; Lin, L.-L.; Wu, H.; Chou, J. J. Autoinhibitory Structure of Preligand Association State Implicates a New Strategy to Attain Effective DR5 Receptor Activation. Cell Research, 2023, 33(2), 131–146. doi: 10.1038/s41422-022-00755-2
  112. Williams, C.; Dong, K. C.; Arkinson, C.; Martin, A. The Ufd1 Cofactor Determines the Linkage Specificity of Polyubiquitin Chain Engagement by the AAA+ ATPase Cdc48. Molecular Cell, 2023, 83(5), 759-769.e7. doi: 10.1016/j.molcel.2023.01.016
  113. Komaniecki, G.; Camarena, M. D. C.; Gelsleichter, E.; Mendoza, R.; Subler, M.; Windle, J. J.; Dozmorov, M. G.; Lai, Z.; Sarkar, D.; Lin, H. Astrocyte Elevated Gene-1 Cys75 S-Palmitoylation by ZDHHC6 Regulates Its Biological Activity. Biochemistry, 2023, 62(2), 543–553. doi: 10.1021/acs.biochem.2c00583
  114. Erstling, J. A.; Naguib, N.; Hinckley, J. A.; Lee, R.; Feuer, G. B.; Tallman, J. F.; Tsaur, L.; Tang, D.; Wiesner, U. B. Antibody Functionalization of Ultrasmall Fluorescent Core–Shell Aluminosilicate Nanoparticle Probes for Advanced Intracellular Labeling and Optical Super Resolution Microscopy. Chem. Mater., 2023, 35(3), 1047–1061. doi: 10.1021/acs.chemmater.2c02963
  115. Mei, X.; Li, J.; Wang, Z.; Zhu, D.; Huang, K.; Hu, S.; Popowski, K. D.; Cheng, K. An Inhaled Bioadhesive Hydrogel to Shield Non-Human Primates from SARS-CoV-2 Infection. Nature Materials, 2023, 22(7), 903–912. doi: 10.1038/s41563-023-01475-7
  116. Hade, M. D.; Suire, C. N.; Suo, Z. An Effective Peptide-Based Platform for Efficient Exosomal Loading and Cellular Delivery of a MicroRNA. ACS Appl. Mater. Interfaces, 2023, 15(3), 3851–3866. doi: 10.1021/acsami.2c20728
  117. Dzhuzha, A. Y.; Tarasenko, I. I.; Atanase, L. I.; Lavrentieva, A.; Korzhikova-Vlakh, E. G. Amphiphilic Polypeptides Obtained by the Post-Polymerization Modification of Poly(Glutamic Acid) and Their Evaluation as Delivery Systems for Hydrophobic Drugs. International Journal of Molecular Sciences, 2023, 24(2), 1049. doi: 10.3390/ijms24021049
  118. Tola, A. J.; Missihoun, T. D. Ammonium Sulfate-Based Prefractionation Improved Proteome Coverage and Detection of Carbonylated Proteins in Arabidopsis Thaliana Leaf Extract. Planta, 2023, 257(3), 62. doi: 10.1007/s00425-023-04083-6
  119. De Prisco, N.; Ford, C.; Elrod, N. D.; Lee, W.; Tang, L. C.; Huang, K.-L.; Lin, A.; Ji, P.; Jonnakuti, V. S.; Boyle, L.; Cabaj, M.; Botta, S.; Õunap, K.; Reinson, K.; Wojcik, M. H.; Rosenfeld, J. A.; Bi, W.; Tveten, K.; Prescott, T.; Gerstner, T.; Schroeder, A.; Fong, C.-T.; George-Abraham, J. K.; Buchanan, C. A.; Hanson-Khan, A.; Bernstein, J. A.; Nella, A. A.; Chung, W. K.; Brandt, V.; Jovanovic, M.; Targoff, K. L.; Yalamanchili, H. K.; Wagner, E. J.; Gennarino, V. A. Alternative Polyadenylation Alters Protein Dosage by Switching between Intronic and 3′UTR Sites. Sci. Adv., 2023, 9(7), eade4814. doi: 10.1126/sciadv.ade4814
  120. Shin, J.; Mir, H.; Khurram, M. A.; Fujihara, K. M.; Dynlacht, B. D.; Cardozo, T. J.; Possemato, R. Allosteric Regulation of CAD Modulates de Novo Pyrimidine Synthesis during the Cell Cycle. Nature Metabolism, 2023, 5(2), 277–293.. doi: 10.1038/s42255-023-00735-9
  121. Zhou, L.; He, F.; Xiang, X.; Dong, C.; Xiang, T.; Li, X.; Li, H.; Bu, L.; Wang, Y.; Ma, X. Radioactive and Fluorescent Dual Modality Cysteine Cathepsin B Activity-Based Probe for Cancer Theranostics. Mol. Pharmaceutics, 2023, 20(7), 3539–3548. doi: 10.1021/acs.molpharmaceut.3c00148
  122. Chen, P.; Pan, K.; Song, N.; Yang, Y.; Gu, C.; Zhong, P.; Li, L.; Li, M.; Zhang, Y.; Dai, Z.; Shangguan, L.; Lei, C.; Liu, Z.; Zhang, J.; Tang, R.; Liu, C.; Fan, S.; Lin, X. A Natural Extracellular Matrix Hydrogel through Selective Nutrient Restriction for Hyperinflammatory Starvation Therapy. Matter, 2023, 6(2), 397–428. doi: 10.1016/j.matt.2022.12.002
  123. Luo, M.; Li, Y.; Peng, B.; White, J.; Mäkilä, E.; Tong, W. Y.; Jonathan Choi, C. H.; Day, B.; Voelcker, N. H. A Multifunctional Porous Silicon Nanocarrier for Glioblastoma Treatment. Mol. Pharmaceutics, 2023, 20(1), 545–560. doi: 10.1021/acs.molpharmaceut.2c00763
  124. Luo, M.; Li, Y.; Peng, B.; White, J.; Mäkilä, E.; Tong, W. Y.; Jonathan Choi, C. H.; Day, B.; Voelcker, N. H. A Multifunctional Porous Silicon Nanocarrier for Glioblastoma Treatment. Mol. Pharmaceutics, 2023, 20(1), 545–560. doi: 10.1021/acs.molpharmaceut.2c00763
  125. Dirscherl, C. F.; Ianeselli, A.; Tetiker, D.; Matreux, T.; Queener, R. M.; Mast, C. B.; Braun, D. A Heated Rock Crack Captures and Polymerizes Primordial DNA and RNA. Phys. Chem. Chem. Phys., 2023, 25(4), 3375–3386. doi: 10.1039/D2CP04538A
  126. Zhao, Z.; A. Ortega-Rivera, O.; Hun Chung, Y.; Simms, A.; F. Steinmetz, N. A Co-Formulated Vaccine of Irradiated Cancer Cells and Cowpea Mosaic Virus Improves Ovarian Cancer Rejection. Journal of Materials Chemistry B, 2023, 11(24), 5429–5441. doi: 10.1039/D2TB02355E
  127. Kowalski, K. A. Brief Survey on the Application of Metal-Catalyzed Azide–Alkyne Cycloaddition Reactions to the Synthesis of Ferrocenyl-x-1,2,3-Triazolyl-R (x = None or a Linker and R = Organic Entity) Compounds with Anticancer Activity. Coordination Chemistry Reviews, 2023, 479, 214996. doi: 10.1016/j.ccr.2022.214996
  128. Radion, E. I.; Mukhin, V. E.; Kholodova, A. V.; Vladimirov, I. S.; Alsaeva, D. Y.; Zhdanova, A. S.; Ulasova, N. Y.; Bulanova, N. V.; Makarov, V. V.; Keskinov, A. A.; Yudin, S. M. Functional Characteristics of Serum Anti-SARS-CoV-2 Antibodies against Delta and Omicron Variants after Vaccination with Sputnik V. Viruses, 2023, 15(6). doi: 10.3390/v15061349
  129. Visentin, A.; Demitroff, N.; Salgueiro, M.; Borkosky, S. S.; Uversky, V. N.; Camporeale, G.; de Prat-Gay, G. Assembly of the Tripartite and RNA Condensates of the Respiratory Syncytial Virus Factory Proteins In Vitro: Role of the Transcription Antiterminator M2-1. Viruses, 2023, 15(6), 1329. doi: 10.3390/v15061329
  130. Tong, Z.; Xie, Y.; Arno, M. C.; Zhang, Y.; Manners, I.; O’Reilly, R. K.; Dove, A. P. Uniform Segmented Platelet Micelles with Compositionally Distinct and Selectively Degradable Cores. Nature Chemistry, 2023, 15(6), 824–831. doi: 10.1038/s41557-023-01177-2
  131. Li, Z.; Zhang, L.; Zhou, L.; Li, X.; Zhao, Y.; Wang, J. Tunable Catalytic Release of Nitric Oxide via Copper-Loaded Coatings on Titanium Nanotubes for Regulating Biological Performance. Biosurface and Biotribology, 2023, 9(2), 45–57. doi: 10.1049/bsb2.12060
  132. Itzhaki, E.; Chausky-Barzakh, E.; Atkins, A.; Bareket-Samish, A.; Stemmer, S. M.; Margel, S.; Moskovits, N. Tumor-Targeted Poly(ArgGlyAsp) Nanocapsules for Personalized Cancer Therapy – In Vivo Study. Advanced Therapeutics, 2023, 6(6), 2200337. doi: 10.1002/adtp.202200337
  133. Deng, W.; Ren, G.; Luo, J.; Gao, S.; Huang, W.; Liu, W.; Ye, S. TRPM7 Mediates Endoplasmic Reticulum Stress and Ferroptosis in Sepsis-Induced Myocardial Injury. Journal of Bioenergetics and Biomembranes, 2023, 55(3), 207–217. doi: 10.1007/s10863-023-09968-5
  134. Nanjaiah, H.; Moudgil, K. D. The Utility of Peptide Ligand-Functionalized Liposomes for Subcutaneous Drug Delivery for Arthritis Therapy. International Journal of Molecular Sciences, 2023, 24(8), 6883. doi: 10.3390/ijms24086883
  135. Hiroki, H.; Ishii, Y.; Piao, J.; Namikawa, Y.; Masutani, M.; Honda, H.; Akahane, K.; Inukai, T.; Morio, T.; Takagi, M. Targeting Poly(ADP)Ribose Polymerase in BCR/ABL1-Positive Cells. Scientific Reports, 2023, 13(1), 7588. doi: 10.1038/s41598-023-33852-2
  136. Subrahmanyam, N.; Yathavan, B.; Yu, S. M.; Ghandehari, H. Targeting Intratibial Osteosarcoma Using Water-Soluble Copolymers Conjugated to Collagen Hybridizing Peptides. Mol. Pharmaceutics, 2023, 20(3), 1670–1680. doi: 10.1021/acs.molpharmaceut.2c00880
  137. Ding, T.; Ji, J.; Zhang, W.; Liu, Y.; Liu, B.; Han, Y.; Chen, C.; Yu, L. The Phosphatidylinositol (4,5)-Bisphosphate-Rab35 Axis Regulates Migrasome Formation. Cell Research, 2023, 33(8), 617–627. doi: 10.1038/s41422-023-00811-5
  138. Damstra, H. G. J.; Mohar, B.; Eddison, M.; Akhmanova, A.; Kapitein, L. C.; Tillberg, P. W. Ten-Fold Robust Expansion Microscopy. Bio Protoc, 2023, 13(12), e4698. doi: 10.21769/BioProtoc.4698
  139. Wiesner, W.; Kühnel, R. M.; Pomorski, T. G. Synthesis and Purification of Lipid-Conjugated Fluorescent PH Sensors. Bio Protoc, 2023, 13(11), e4694. doi: 10.21769/BioProtoc.4694
  140. Dang, W.; Xing, B.; Jia, X.; Zhang, Y.; Jia, B.; Yu, C.; He, J.; Li, Z.; Li, H.; Liu, Z. Subcellular Organelle-Targeted Nanostructured Lipid Carriers for the Treatment of Metastatic Breast Cancer. IJN, 2023, 18, 3047–3068. doi: 10.2147/IJN.S413680
  141. Sun, X.-L.; Chen, Z.-H.; Guo, X.; Wang, J.; Ge, M.; Wong, S. Z. H.; Wang, T.; Li, S.; Yao, M.; Johnston, L. A.; Wu, Q.-F. Stem Cell Competition Driven by the Axin2-P53 Axis Controls Brain Size during Murine Development. Developmental Cell, 2023, 58(9), 744-759.e11. doi: 10.1016/j.devcel.2023.03.016
  142. Rodgers, M. L.; O’Brien, B.; Woodson, S. A. Small RNAs and Hfq Capture Unfolded RNA Target Sites during Transcription. Molecular Cell, 2023, 83(9), 1489-1501.e5. doi: 10.1016/j.molcel.2023.04.003.
  143. Shevchuk, A. I.; Svinko, V. O.; Smirnov, A. N.; Solovyeva, E. V. SERS Study of Cyanine Dyes: Optimization of Metal Core and Molecular Label Choice for Plasmonic Nanotags. Dyes and Pigments, 2023, 216, 111329. doi: 10.1016/j.dyepig.2023.111329.
  144. Ji, Y.; Chakraborty, T.; Wegner, S. V. Self-Regulated and Bidirectional Communication in Synthetic Cell Communities. ACS Nano, 2023, 17(10), 8992–9002. doi: 10.1021/acsnano.2c09908
  145. Sahu, A.; Min, K.; Jeon, S. H.; Kwon, K.; Tae, G. Self-Assembled Hemin-Conjugated Heparin with Dual-Enzymatic Cascade Reaction Activities for Acute Kidney Injury. Carbohydrate Polymers, 2023, 316, 121088. doi: 10.1016/j.carbpol.2023.121088
  146. Gu, J.; Sun, J.; Tian, K.; Bian, J.; Peng, J.; Xu, S.; Zhao, L. Reversal of Hepatic Fibrosis by the Co-Delivery of Drug and Ribonucleoprotein-Based Genome Editor. Biomaterials, 2023, 298, 122133. doi: 10.1016/j.biomaterials.2023.122133
  147. Martín-Asensio, A.; Dávila, S.; Cacheux, J.; Lindstaedt, A.; Dziadosz, A.; Witt, D.; Calero, M.; Balaz, I.; Rodríguez, I. Recapitulating Solid Stress on Tumor on a Chip for Nanomedicine Diffusive Transport Prediction. Advanced NanoBiomed Research, 2023, 3(6), 2200164. doi: 10.1002/anbr.202200164
  148. Ardana, A.; Ghosh, S.; Huda, P.; Fletcher, N. L.; Thurecht, K. J.; Williams, C. C. RAFT Polymer–Antibody Conjugation: Squaramide Ester Chemistry Leads to Conjugates with a Therapeutic Anti-EGFR Antibody with Full Retention of Activity and Increased Tumor Uptake In Vivo. Mol Pharmaceutics, 2023, 20(6), 3073–3087. doi: 10.1021/acs.molpharmaceut.3c00085
  149. Lu, Y.; Zhang, M.; Zhang, J.; Jiang, M.; Bai, G. Psoralen Prevents the Inactivation of Estradiol and Treats Osteoporosis via Covalently Targeting HSD17B2. Journal of Ethnopharmacology, 2023, 311, 116426. doi: 10.1016/j.jep.2023.116426
  150. Xu, X.; Wang, C.; Guan, W.; Wang, F.; Li, X.; Yuan, J.; Xu, G. Protoporphyrin IX-Loaded Albumin Nanoparticles Reverse Cancer Chemoresistance by Enhancing Intracellular Reactive Oxygen Species. Nanomedicine: Nanotechnology, Biology and Medicine, 2023, 51, 102688. doi: 10.1016/j.nano.2023.102688
  151. Zueva, A. O.; Silchenko, A. S.; Rasin, A. B.; Malyarenko, O. S.; Kusaykin, M. I.; Kalinovsky, A. I.; Ermakova, S. P. Production of High- and Low-Molecular Weight Fucoidan Fragments with Defined Sulfation Patterns and Heightened in Vitro Anticancer Activity against TNBC Cells Using Novel Endo-Fucanases of the GH107 Family. Carbohydrate Polymers, 2023, 318, 121128. doi: 10.1016/j.carbpol.2023.121128
  152. Luo, J.; Zhao, X.; Guo, B.; Han, Y. Preparation, Thermal Response Mechanisms and Biomedical Applications of Thermosensitive Hydrogels for Drug Delivery. Expert Opinion on Drug Delivery, 2023, 20(5), 641–672. doi: 10.1080/17425247.2023.2217377
  153. Guirguis, N.; Machuca-Parra, A. I.; Matoori, S. Portable Near-Infrared Fluorometer for a Liposomal Blood Lactate Assay. ACS Pharmacol Transl Sci, 2023, 6(6), 907–912. doi: 10.1021/acsptsci.3c00055
  154. Okamoto, W.; Usui, T.; Hasegawa, M.; Kobayashi, T.; Fujisawa, J.; Taguchi, K.; Matsumoto, K.; Kohno, M.; Iwazaki, M.; Shimano, S.; Nagao, I.; Toyoda, H.; Matsumura, N.; Tomiyasu, H.; Tochinai, R.; Komatsu, T. Polyoxazoline-Conjugated Porcine Serum Albumin as an Artificial Plasma Expander for Dogs. Sci Rep, 2023, 13(1), 9512. doi: 10.1038/s41598-023-35999-4
  155. Wu, Y.; Leyk, S.; Torabi, H.; Höhn, K.; Honecker, B.; Tauler, M. D. P. M.; Cadar, D.; Jacobs, T.; Bruchhaus, I.; Metwally, N. G. Plasmodium Falciparum Infection Reshapes the Human MicroRNA Profiles of Red Blood Cells and Their Extracellular Vesicles. iScience, 2023, 26(7), 107119. doi: 10.1016/j.isci.2023.107119
  156. Protas, V. V.; Pogossyan, G. P.; Li, K. G.; Zhumina, A. G.; Bisseneva, A. K.; Shaikina, D. N. Plasma 25-Hydroxyvitamin D Level and VDR Gene Single Nucleotide Polymorphism Rs2228570 Influence on COVID-19 Susceptibility among the Kazakh Ethnic Group—A Pilot Study. Nutrients, 2023, 15(7), 1781. doi: 10.3390/nu15071781
  157. Sandberg, E.; Piguet, J.; Kostiv, U.; Baryshnikov, G.; Liu, H.; Widengren, J. Photoisomerization of Heptamethine Cyanine Dyes Results in Red-Emissive Species: Implications for Near-IR, Single-Molecule, and Super-Resolution Fluorescence Spectroscopy and Imaging. J Phys Chem B, 2023, 127(14), 3208–3222. doi: 10.1021/acs.jpcb.2c08016
  158. Yao, P.; Wang, X.; Wang, Q.; Dai, Q.; Peng, Y.; Yuan, Q.; Mou, N.; Lv, S.; Weng, B.; Wang, Y.; Sun, F. Cyclic RGD-Functionalized PH/ROS Dual-Responsive Nanoparticle for Targeted Breast Cancer Therapy. Pharmaceutics, 2023, 15(7), 1827. doi: 10.3390/pharmaceutics15071827
  159. Deiss-Yehiely, E.; Cárcamo-Oyarce, G.; Berger, A. G.; Ribbeck, K.; Hammond, P. T. PH-Responsive, Charge-Reversing Layer-by-Layer Nanoparticle Surfaces Enhance Biofilm Penetration and Eradication. ACS Biomater Sci Eng, 2023, 9(8), 4794–4804. doi: 10.1021/acsbiomaterials.3c00481
  160. Ponomartsev, N.; Zilov, D.; Gushcha, E.; Travina, A.; Sergeev, A.; Enukashvily, N. Overexpression of Pericentromeric HSAT2 DNA Increases Expression of EMT Markers in Human Epithelial Cancer Cell Lines. International Journal of Molecular Sciences, 2023, 24(8), 6918. doi: 10.3390/ijms24086918
  161. Schvartzman, J.-M.; Forsyth, G.; Walch, H.; Chatila, W.; Taglialatela, A.; Lee, B. J.; Zhu, X.; Gershik, S.; Cimino, F. V.; Santella, A.; Menghrajani, K.; Ciccia, A.; Koche, R.; Sánchez-Vega, F.; Zha, S.; Thompson, C. B. Oncogenic IDH Mutations Increase Heterochromatin-Related Replication Stress without Impacting Homologous Recombination. Molecular Cell, 2023, 83(13), 2347-2356.e8. doi: 10.1016/j.molcel.2023.05.026
  162. Pinto, R. M.; Yazdani, S.; Seabra, C. L.; De Jonge, M.; Izci, M.; Cruz, R.; Casal, S.; Soenen, S. J.; Reis, S.; Nunes, C.; Van Dijck, P. Non Disseminative Nano-Strategy against in Vivo Staphylococcus Aureus Biofilms. npj Biofilms Microbiomes, 2023, 9(1), 1-15. doi: 10.1038/s41522-023-00405-4
  163. Zhao, Z.; Li, C.; Zhang, Y.; Li, C.; Chu, Y.; Li, X.; Liu, P.; Chen, H.; Wang, Y.; Su, B.; Chen, Q.; Sun, T.; Jiang, C. Nanomaterials with Dual Immunomodulatory Functions for Synergistic Therapy of Breast Cancer Brain Metastases. Bioactive Materials, 2023, 27, 474–487. doi: 10.1016/j.bioactmat.2023.04.021
  164. Naeimipour, S.; Boroojeni, F. R.; Lifwergren, P.; Selegård, R.; Aili, D. Multimodal andDynamic Cross-Linking of Modular Thiolated Alginate-Based Bioinks. Materials Today Advances, 2023, 19, 100415. doi: 10.1016/j.mtadv.2023.100415
  165. Hyun, G. H.; Jeong, D.-H.; Yang, Y. Y.; Cho, I. H.; Ha, Y.-J.; Xing, X.; Abbott, D. W.; Hsieh, Y. S. Y.; Kang, Y. P.; Cha, J.-H.; Hong, S.-S.; Lee, S. J.; Kim, Y.-S.; Kwon, S. W. Multivalent Carbohydrate Nanocomposites for Tumor Microenvironment Remodeling to Enhance Antitumor Immunity. ACS Nano, 2023, 17(12), 11567–11582. doi: 10.1021/acsnano.3c01645
  166. Ji, F.; Hur, M.; Hur, S.; Wang, S.; Sarkar, P.; Shao, S.; Aispuro, D.; Cong, X.; Hu, Y.; Li, Z.; Xue, M. Multiplex Protein Imaging through PACIFIC: Photoactive Immunofluorescence with Iterative Cleavage. ACS Bio Med Chem Au, 2023, 3(3), 283–294. doi: 10.1021/acsbiomedchemau.3c00018
  167. Smirnov, A. N.; Aslanov, S. F.; Danilov, D. V.; Kurapova, O. Yu.; Solovyeva, E. V. One-Pot Synthesis of Silica-Coated Gold Nanostructures Loaded with Cyanine 5.5 for Cell Imaging by SERS Spectroscopy. Nanomaterials, 2023, 13(7), 1267. doi: 10.3390/nano13071267
  168. Saveleva, M. S.; Lobanov, M. E.; Gusliakova, O. I.; Plastun, V. O.; Prikhozhdenko, E. S.; Sindeeva, O. A.; Gorin, D. A.; Mayorova, O. A. Mucoadhesive Emulsion Microgels for Intravesical Drug Delivery: Preparation, Retention at Urothelium, and Biodistribution Study. ACS Appl Mater Interfaces, 2023, 15(21), 25354–25368. doi: 10.1021/acsami.3c02741
  169. Gmoshinskiy, V. I.; Novozhilov, Yu. K.; Prikhodko, I. S.; Bortnikov, F. M.; Shchepin, O. N.; Schnittler, M. Morphology and phylogeny of Diderma aurantiacum (Myxomycetes) — a new species for Russia from the Far East. Novosti sistematiki nizshikh rastenii, 2023, 57(1), 27–42. doi: 10.31111/nsnr/2023.57.1.27
  170. Mustafa, R. A.; Parkkila, P.; Rosenholm, J. M.; Zhang, H.; Viitala, T. Monitoring Silica Core@shell Nanoparticle-Bacterial Film Interactions Using the Multi-Parametric Surface Plasmon Resonance Technique. Smart Medicine, 2023, 2(3), e20230012. doi: 10.1002/SMMD.20230012
  171. Salgueiro, M.; Camporeale, G.; Visentin, A.; Aran, M.; Pellizza, L.; Esperante, S. A.; Corbat, A.; Grecco, H.; Sousa, B.; Esperón, R.; Borkosky, S. S.; de Prat-Gay, G. Molten Globule Driven and Self-Downmodulated Phase Separation of a Viral Factory Scaffold. Journal of Molecular Biology, 2023, 435(16), 168153. doi: 10.1016/j.jmb.2023.168153
  172. Xavier da Silva, T. N.; Schulte, C.; Alves, A. N.; Maric, H. M.; Friedmann Angeli, J. P. Molecular Characterization of AIFM2/FSP1 Inhibition by IFSP1-like Molecules. Cell Death & Disease, 2023, 14(4), 281. doi: 10.1038/s41419-023-05787-z
  173. Wang, Y.; Ling, X.; Zhang, C.; Zou, J.; Luo, B.; Luo, Y.; Jia, X.; Jia, G.; Zhang, M.; Hu, J.; Liu, T.; Wang, Y.; Lu, K.; Li, D.; Ma, J.; Liu, C.; Su, Z. Modular Characterization of SARS-CoV-2 Nucleocapsid Protein Domain Functions in Nucleocapsid-like Assembly. Molecular Biomedicine, 2023, 4(1), 16. doi: 10.1186/s43556-023-00129-z
  174. Somsen, B. A.; Sijbesma, E.; Leysen, S.; Honzejkova, K.; Visser, E. J.; Cossar, P. J.; Obšil, T.; Brunsveld, L.; Ottmann, C. Molecular Basis and Dual Ligand Regulation of Tetrameric Estrogen Receptor α/14-3-3ζ Protein Complex. Journal of Biological Chemistry, 2023, 299(7), 104855. doi: 10.1016/j.jbc.2023.104855
  175. Tong, L.; Zhang, S.; Liu, Q.; Huang, C.; Hao, H.; Tan, M. S.; Yu, X.; Lou, C. K. L.; Huang, R.; Zhang, Z.; Liu, T.; Gong, P.; Ng, C. H.; Muthiah, M.; Pastorin, G.; Wacker, M. G.; Chen, X.; Storm, G.; Lee, C. N.; Zhang, L.; Yi, H.; Wang, J.-W. Milk-Derived Extracellular Vesicles Protect Intestinal Barrier Integrity in the Gut-Liver Axis. Sci Adv, 2023, 9(15), eade5041. doi: 10.1126/sciadv.ade5041
  176. Salova, V. D.; Kholdina, A. M.; Melnik, A. D.; Zayulina, K. S.; Elcheninov, A. G.; Klyukina, A. A.; Kublanov, I. V. Microbial Communities Associated with the White Sea Red Algae as a Source of Xylanolytic Microorganisms. Microbiology, 2023, 92(3), 418–426. doi: 10.1134/S002626172360026X
  177. Das, S. K.; Huynh, M. T.; Gao, J.; Sengupta, B.; Yadav, S. P.; Lee, T.-H. Methods to Investigate Nucleosome Structure and Dynamics with Single-Molecule FRET. Methods, 2023, 215, 17–27. doi: 10.1016/j.ymeth.2023.05.003
  178. Park, H. H.; Wang, B.; Moon, S.; Jepson, T.; Xu, K. Machine-Learning-Powered Extraction of Molecular Diffusivity from Single-Molecule Images for Super-Resolution Mapping. Commun Biol, 2023, 6(1), 1-8. doi: 10.1038/s42003-023-04729-x
  179. Watanabe, T.; Mizuno, H. L.; Norimatsu, J.; Obara, T.; Cabral, H.; Tsumoto, K.; Nakakido, M.; Kawauchi, D.; Anraku, Y. Ligand Installation to Polymeric Micelles for Pediatric Brain Tumor Targeting. Polymers, 2023, 15(7), 1808. doi: 10.3390/polym15071808
  180. Barkovich, K. J.; Zhao, Z.; Steinmetz, N. F. IRGD-Targeted Physalis Mottle Virus Like Nanoparticles for Targeted Cancer Delivery. Small Science, 2023, 3(8), 2300067. doi: 10.1002/smsc.202300067
  181. Matthews, M. D.; Cook, E.; Naguib, N.; Wiesner, U. B.; Lewis, K. J. Intravital Imaging of Osteocyte Integrin Dynamics with Locally Injectable Fluorescent Nanoparticles. Bone, 2023, 174, 116830. doi: 10.1016/j.bone.2023.116830
  182. Lam, A. D.; Styles, I. K.; Senyschyn, D.; Cao, E.; Anshabo, A.; Abdallah, M.; Mikrani, R.; Nowell, C. J.; Porter, C. J. H.; Feeney, O. M.; Trevaskis, N. L. Intra-Articular Injection of a B Cell Depletion Antibody Enhances Local Exposure to the Joint-Draining Lymph Node in Mice with Collagen-Induced Arthritis. Mol Pharmaceutics, 2023, 20(4), 2053–2066. doi: 10.1021/acs.molpharmaceut.2c01041
  183. Liu, C.; Tong, Y. W. Interfacial Polyelectrolyte Complexation-Inspired Bioprinting of Vascular Constructs. ACS Appl Mater Interfaces, 2023, 15(17), 20712–20725. doi: 10.1021/acsami.3c01199
  184. Kolyvanova, M. A.; Klimovich, M. A.; Dement’eva, O. V.; Rudoy, V. M.; Kuzmin, V. A.; Trofimov, A. V.; Morozov, V. N. Interaction of Gold Nanoparticles with Cyanine Dyes in Cholesteric DNA Submicroparticles: Impact of the Way of Their Introduction into the System. Russian Journal of Physical Chemistry B, 2023, 17(1), 206–214. doi: 10.1134/S1990793123010062
  185. Chetverikov, P. E.; Craemer, C.; Gankevich, V. D.; Zhuk, A. S. Integrative Taxonomy of the Gall Mite Nothopoda Todeica n. Sp. (Eriophyidae) from the Disjunct Afro-Australasian Fern Todea Barbara: Morphology, Phylogeny, and Mitogenomics. Insects, 2023, 14(6), 507. doi: 10.3390/insects14060507
  186. Schoenmakers, L. L. J.; Yewdall, N. A.; Lu, T.; André, A. A. M.; Nelissen, Frank. H. T.; Spruijt, E.; Huck, W. T. S. In Vitro Transcription–Translation in an Artificial Biomolecular Condensate. ACS Synth Biol, 2023, 12(7), 2004–2014. doi: 10.1021/acssynbio.3c00069
  187. Lu, J.; Zhu, X.; Zhang, M.; Jiang, X.; Guo, W.; Jiang, F.; Cao, F. In Vitro and in Vivo Assessment of Structural Integrity for HPCD Complex@Liposome Nanocomposites from Ocular Surface to the Posterior Segment of the Eye. Carbohydrate Polymers, 2023, 315, 120960. doi: 10.1016/j.carbpol.2023.120960
  188. Godino, E.; Restrepo Sierra, A. M.; Danelon, C. Imaging Flow Cytometry for High-Throughput Phenotyping of Synthetic Cells. ACS Synth Biol, 2023, 12(7), 2015–2028. doi: 10.1021/acssynbio.3c00074
  189. Sim, J.; Li, M.; Park, K. M.; Kim, K. Identification of Mitochondrial Proteins Associated with Cyanine 5 Using a Combination of Affinity-Based Photocrosslinking with Bio-Orthogonal Supramolecular Latching. J. Porphyrins Phthalocyanines, 2023, 27(07n10), 1148–1155. doi: 10.1142/S108842462350058X
  190. Nasimi, H.; Madsen, J. S.; Zedan, A. H.; Malmendal, A.; Osther, P. J. S.; Alatraktchi, F. A. Identification of Early Stage and Metastatic Prostate Cancer Using Electrochemical Detection of Beta-2-Microglobulin in Urine Samples from Patients. Scientific Reports, 2023, 13(1), 10658. doi: 10.1038/s41598-023-37886-4
  191. Malfanti, A.; Bausart, M.; Vanvarenberg, K.; Ucakar, B.; Préat, V. Hyaluronic Acid-Antigens Conjugates Trigger Potent Immune Response in Both Prophylactic and Therapeutic Immunization in a Melanoma Model. Drug Delivery and Translational Research, 2023, 13(10), 2550–2567. doi: 10.1007/s13346-023-01337-4
  192. Purohit, M. P.; Kar, A. K.; Kumari, M.; Ghosh, D.; Patnaik, S. Heparin Biofunctionalized Selenium Nanoparticles as Potential Antiangiogenic–Chemotherapeutic Agents for Targeted Doxorubicin Delivery. ACS Appl Mater Interfaces, 2023, 15(16), 19904–19920. doi: 10.1021/acsami.3c00219
  193. Kim, G. B.; Kim, S.; Hwang, Y. H.; Kim, S.; Lee, I.; Kim, S. A.; Goo, J.; Yang, Y.; Jeong, C.; Nam, G.-H.; Kim, I.-S. Harnessing Oncolytic Extracellular Vesicles for Tumor Cell-Preferential Cytoplasmic Delivery of Misfolded Proteins for Cancer Immunotherapy. Small, 2023, 19(37), 2300527. doi: 10.1002/smll.202300527
  194. Liu, H.-J.; Chen, W.; Wu, G.; Zhou, J.; Liu, C.; Tang, Z.; Huang, X.; Gao, J.; Xiao, Y.; Kong, N.; Joshi, N.; Cao, Y.; Abdi, R.; Tao, W. Glutathione-Scavenging Nanoparticle-Mediated PROTACs Delivery for Targeted Protein Degradation and Amplified Antitumor Effects. Advanced Science, 2023, 10(16), 2207439. doi: 10.1002/advs.202207439
  195. Lu, Y.; Zhou, J.; Wang, Q.; Cai, J.; Yu, B.; Dai, Q.; Bao, Y.; Chen, R.; Zhang, Z.; Zhang, D.; Hou, T. Glucocorticoid-Loaded PH/ROS Dual-Responsive Nanoparticles Alleviate Joint Destruction by Downregulating the NF-ΚB Signaling Pathway. Acta Biomaterialia, 2023, 164, 458–473. doi: 10.1016/j.actbio.2023.04.012
  196. Kim, J.; Won, J.; Chung, D. K.; Lee, H. H. FRET Analysis of the Temperature-Induced Structural Changes in Human TRPV3. Scientific Reports, 2023, 13(1), 10108. doi: 10.1038/s41598-023-36885-9
  197. Wang, Q.; Yu, Y.; Chang, Y.; Xu, X.; Wu, M.; Ediriweera, G. R.; Peng, H.; Zhen, X.; Jiang, X.; Searles, D. J.; Fu, C.; Whittaker, A. K. Fluoropolymer-MOF Hybrids with Switchable Hydrophilicity for 19F MRI-Monitored Cancer Therapy. ACS Nano, 2023, 17(9), 8483–8498. doi: 10.1021/acsnano.3c00694
  198. Maltseva, D.; Chatterjee, S.; Yu, C.-C.; Brzezinski, M.; Nagata, Y.; Gonella, G.; Murthy, A. C.; Stachowiak, J. C.; Fawzi, N. L.; Parekh, S. H.; Bonn, M. Fibril Formation and Ordering of Disordered FUS LC Driven by Hydrophobic Interactions. Nature Chemistry, 2023, 15(8), 1146–1154. doi: 10.1038/s41557-023-01221-1
  199. Byun, J.; Wu, Y.; Lee, J.; Kim, J. S.; Shim, G.; Oh, Y.-K. External Cold Atmospheric Plasma-Responsive on-Site Hydrogel for Remodeling Tumor Immune Microenvironment. Biomaterials, 2023, 299, 122162. doi: 10.1016/j.biomaterials.2023.122162
  200. Rezaei, S.; de Araújo Júnior, R. F.; da Silva, I. L. G.; Schomann, T.; Eich, C.; Cruz, L. J. Erythrocyte−cancer Hybrid Membrane-Coated Reduction-Sensitive Nanoparticles for Enhancing Chemotherapy Efficacy in Breast Cancer. Biomaterials Advances, 2023, 151, 213456. doi: 10.1016/j.bioadv.2023.213456
  201. Ianshina, T.; Sidorin, A.; Petrova, K.; Shubert, M.; Makeeva, A.; Sambuk, E.; Govdi, A.; Rumyantsev, A.; Padkina, M. Effect of Methionine on Gene Expression in Komagataella Phaffii Cells. Microorganisms, 2023, 11(4), 877. doi: 10.3390/microorganisms11040877
  202. Aldag, P.; Rutkauskas, M.; Madariaga-Marcos, J.; Songailiene, I.; Sinkunas, T.; Kemmerich, F.; Kauert, D.; Siksnys, V.; Seidel, R. Dynamic Interplay between Target Search and Recognition for a Type I CRISPR-Cas System. Nature Communications, 2023, 14(1), 3654. doi: 10.1038/s41467-023-38790-1
  203. Prabhakar, A.; Pavlov, M. Y.; Zhang, J.; Indrisiunaite, G.; Wang, J.; Lawson, M. R.; Ehrenberg, M.; Puglisi, J. D. Dynamics of Release Factor Recycling during Translation Termination in Bacteria. Nucleic Acids Research, 2023, 52(11), 5774–5790. doi: 10.1093/nar/gkad286
  204. Konhäuser, M.; Kannaujiya, V. K.; Kaltbeitzel, J.; Winterwerber, P.; Böhm, E.; Breitenbach, B.; Wich, P. R. Dual-Responsive Enzyme–Polysaccharide Conjugate as a Nanocarrier System for Enzyme Prodrug Therapy. Biomacromolecules, 2023, 24(5), 2138–2148. doi: 10.1021/acs.biomac.3c00031
  205. Emami, F.; Duwa, R.; Banstola, A.; Woo, S. M.; Kwon, T. K.; Yook, S. Dual Receptor Specific Nanoparticles Targeting EGFR and PD-L1 for Enhanced Delivery of Docetaxel in Cancer Therapy. Biomedicine & Pharmacotherapy, 2023, 165, 115023. doi: 10.1016/j.biopha.2023.115023
  206. Chen, Y.-C.; Li, Y.; Yan, C.-C. S.; Hsu, C.-P.; Cheng, P.-L.; Tu, H.-L. DNA Tension Assays Reveal That Force-Dependent Integrin Activation Regulates Neurite Outgrowth in Primary Cortical Neurons. Biomaterials Advances, 2023, 150, 213431. doi: 10.1016/j.bioadv.2023.213431
  207. Monzó, C.; Gkioni, L.; Beyer, A.; Valenzano, D. R.; Grönke, S.; Partridge, L. Dietary Restriction Mitigates the Age-Associated Decline in Mouse B Cell Receptor Repertoire Diversity. Cell Reports, 2023, 42(7), 112722. doi: 10.1016/j.celrep.2023.112722
  208. Zabegina, L.; Zyatchin, I.; Kniazeva, M.; Shalaev, A.; Berkut, M.; Sharoyko, V.; Mikhailovskii, V.; Kondratov, K.; Reva, S.; Nosov, A.; Malek, A. Diagnosis of Prostate Cancer through the Multi-Ligand Binding of Prostate-Derived Extracellular Vesicles and MiRNA Analysis. Life, 2023, 13(4), 885. doi: 10.3390/life13040885
  209. Chu, W.; Houston, Z. H.; Fletcher, N. L.; Huda, P.; Ahamed, M.; Lim, T. X.; Day, B. W.; Pinkham, M.; Thurecht, K. J. Development and Validation of a Targeted Treatment for Brain Tumors Using a Multi-Drug Loaded, Relapse-Resistant Polymeric Theranostic. Biomacromolecules, 2023, 24(6), 2674–2690. doi: 10.1021/acs.biomac.3c00138
  210. Chetverikov, Ph.E.; Desnitskiy, A.G.; Klimov, P.B.; Ozman- Sullivan, S.K.; Romanovich, A.E.; Sukhareva, S.I. Deuterogyny and the Association of Two Vagrant Eriophyoid Mites (Acariformes, Eriophyoidea) with the Host-Plant Generative Organs of Two Broad-Leaved Trees in North-West Russia. Zoological Studies, 2023, 62, 35. doi: 10.6620/ZS.2023.62-35
  211. Sakhabutdinova, A. R.; Chemeris, A. V.; Garafutdinov, R. R. Detection of Specific RNA Targets by Multimerization. Biochemistry (Moscow), 2023, 88(5), 679–686. doi: 10.1134/S0006297923050103
  212. Seipp, E. K.; Huang, R. Design and Synthesis of a Fluorescent Probe to Develop a Fluorescence Polarization Assay for the E3 Ligase FEM1C. Bioorganic & Medicinal Chemistry, 2023, 90, 117371. doi: 10.1016/j.bmc.2023.117371
  213. Lawanprasert, A.; Sloand, J. N.; González Vargas, M.; Singh, H.; Eldor, T.; Miller, M. A.; Pimcharoen, S.; Wang, J.; Leighow, S. M.; Pritchard, J. R.; Dokholyan, N. V.; Medina, S. H. Deciphering the Mechanistic Basis for Perfluoroalkyl-Protein Interactions. ChemBioChem, 2023, 24(13), e202300159. doi: 10.1002/cbic.202300159
  214. Feigin, C. Y.; Moreno, J. A.; Ramos, R.; Mereby, S. A.; Alivisatos, A.; Wang, W.; Van Amerongen, R.; Camacho, J.; Rasweiler, J. J.; Behringer, R. R.; Ostrow, B.; Plikus, M. V.; Mallarino, R. Convergent Deployment of Ancestral Functions during the Evolution of Mammalian Flight Membranes. Sci Adv, 2023, 9(12), eade7511. doi: 10.1126/sciadv.ade7511
  215. Zhang, Q.; Li, X.; Huang, K.; Huang, Y.; Zhao, S.; Liu, S.; Li, Y. Controlling the Trimerization of the Collagen Triple-Helix by Solvent Switching. Biomacromolecules, 2023, 24(4), 1689–1699. doi: 10.1021/acs.biomac.2c01475
  216. Mazrad, Z. A. I.; Leiske, M. N.; Tabor, R. F.; Nicolazzo, J. A.; Kempe, K. Comparison of the Anti-Inflammatory Activity and Cellular Interaction of Brush Polymer–N-Acetyl Cysteine Conjugates in Human and Murine Microglial Cell Lines. Mol. Pharmaceutics, 2023, 20(5), 2686–2701. doi: 10.1021/acs.molpharmaceut.3c00140
  217. Svinko, V. O.; Smirnov, A. N.; Shevchuk, A. I.; Demenshin, A. I.; Smirnov, A. A.; Solovyeva, E. V. Comparative Study of Fluorescence Core-Shell Nanotags with Different Morphology of Gold Core. Colloids and Surfaces B: Biointerfaces, 2023, 226, 113306. doi: 10.1016/j.colsurfb.2023.113306
  218. Abil, Z.; Restrepo Sierra, A. M.; Danelon, C. Clonal Amplification-Enhanced Gene Expression in Synthetic Vesicles. ACS Synth Biol, 2023, 12(4), 1187–1203. doi: 10.1021/acssynbio.2c00668
  219. Hostert, J.D.; Sepesy, M. R.; Duval, C. E.;  Renner, J.N. Clickable Polymer Scaffolds Enable Ce Recovery with Peptide Ligands. Soft Matter, 2023, 19(15), 2823–2831. doi: 10.1039/D2SM01664H
  220. Farkas, S.; Cioca, D.; Murányi, J.; Hornyák, P.; Brunyánszki, A.; Szekér, P.; Boros, E.; Horváth, P.; Hujber, Z.; Rácz, G. Z.; Nagy, N.; Tóth, R.; Nyitray, L.; Péterfi, Z. Chlorotoxin Binds to Both Matrix Metalloproteinase 2 and Neuropilin 1. Journal of Biological Chemistry, 2023, 299(9), 104998. doi: 10.1016/j.jbc.2023.104998
  221. Crothers, R. A.; Orr, N. H. P.; van der Meer, B.; Dullens, R. P. A.; Yanagishima, T. Characterization and Optimization of Fluorescent Organosilica Colloids for 3D Confocal Microscopy Prepared Under “Zero-Flow” Conditions. Langmuir, 2023, 39(15), 5306–5314. doi: 10.1021/acs.langmuir.2c03306
  222. Kozlova, T.; Popov, A.; Romanov, M. V.; Savintseva, I.; Vasilyeva, D. N.; Baranchikov, A.; Ivanov, V. Ceric Phosphates and Nanocrystalline Ceria: Selective Toxicity to Melanoma Cells. Nanosystems: Physics, Chemistry, Mathematics, 2023, 14, 223–230. doi: 10.17586/2220-8054-2023-14-2-223-230
  223. Bianchi, A.; De Castro Silva, I.; Deshpande, N. U.; Singh, S.; Mehra, S.; Garrido, V. T.; Guo, X.; Nivelo, L. A.; Kolonias, D. S.; Saigh, S. J.; Wieder, E.; Rafie, C. I.; Dosch, A. R.; Zhou, Z.; Umland, O.; Amirian, H.; Ogobuiro, I. C.; Zhang, J.; Ban, Y.; Shiau, C.; Nagathihalli, N. S.; Montgomery, E. A.; Hwang, W. L.; Brambilla, R.; Komanduri, K.; Villarino, A. V.; Toska, E.; Stanger, B. Z.; Gabrilovich, D. I.; Merchant, N. B.; Datta, J. Cell-Autonomous Cxcl1 Sustains Tolerogenic Circuitries and Stromal Inflammation via Neutrophil-Derived TNF in Pancreatic Cancer. Cancer Discovery, 2023, 13(6), 1428–1453. doi: 10.1158/2159-8290.CD-22-1046
  224. Chang, Y.; Cai, X.; Syahirah, R.; Yao, Y.; Xu, Y.; Jin, G.; Bhute, V. J.; Torregrosa-Allen, S.; Elzey, B. D.; Won, Y.-Y.; Deng, Q.; Lian, X. L.; Wang, X.; Eniola-Adefeso, O.; Bao, X. CAR-Neutrophil Mediated Delivery of Tumor-Microenvironment Responsive Nanodrugs for Glioblastoma Chemo-Immunotherapy. Nature Communications, 2023, 14(1), 2266. doi: 10.1038/s41467-023-37872-4
  225. Wang, H.; Lee, D.; Cao, Y.; Bi, X.; Du, J.; Miao, K.; Wei, L. Bond-Selective Fluorescence Imaging with Single-Molecule Sensitivity. Nature Photonics, 2023, 17(10), 846–855. doi: 10.1038/s41566-023-01243-8
  226. Li, H.; Bruce, G.; Childerhouse, N.; Keegan, G.; Mantovani, G.; Stolnik, S. Biotin Receptor-Mediated Intracellular Delivery of Synthetic Polypeptide-Protein Complexes. Journal of Controlled Release, 2023, 357, 333–341. doi: 10.1016/j.jconrel.2023.03.051
  227. Ivanov, A. V.; Safenkova, I. V.; Zherdev, A. V.; Wan, Y.; Dzantiev, B. B. Comparison of Single-Stranded DNA Probes Conjugated with Magnetic Particles for Trans-Cleavage in Cas12a-Based Biosensors. Biosensors, 2023, 23(7), 700. doi: 10.3390/bios13070700
  228. Rodgers, M. L.; Sun, Y.; Woodson, S. A. Ribosomal Protein S12 Hastens Nucleation of Co-Transcriptional Ribosome Assembly. Biomolecules, 2023, 13(6), 951. doi: 10.3390/biom13060951
  229. Xie, Y.; Ye, J.; Ouyang, Y.; Gong, J.; Li, C.; Deng, Y.; Mai, Y.; Liu, Y.; Deng, W. Microneedle-Assisted Topical Delivery of Idebenone-Loaded Bioadhesive Nanoparticles Protect against UV-Induced Skin Damage. Biomedicines, 2023, 11(6), 1649. doi: 10.3390/biomedicines11061649
  230. Herman, C. E.; Min, L.; Choe, L. H.; Maurer, R. W.; Xu, X.; Ghose, S.; Lee, K. H.; Lenhoff, A. M. Behavior of Host-Cell-Protein-Rich Aggregates in Antibody Capture and Polishing Chromatography. Journal of Chromatography A, 2023, 1702, 464081. doi: 10.1016/j.chroma.2023.464081
  231. Liu, N.; Gujrati, V.; Werner, J. P. F.; Mishra, K.; Anzenhofer, P.; Stiel, A. C.; Mettenleiter, G.; Feuchtinger, A.; Walch, A.; Ntziachristos, V. Bacterial Outer Membrane Vesicles as Cationic Dye Carriers for Optoacoustics-Guided Phototherapy of Cancer. Cancer Nanotechnology, 2023, 14(1), 36. doi: 10.1186/s12645-023-00191-w
  232. Hernández‐Carralero, E.; Cabrera, E.; Rodríguez-Torres, G.; Hernández-Reyes, Y.; Singh, A. N.; Santa-María, C.; Fernández-Justel, J. M.; Janssens, R. C.; Marteijn, J. A.; Evert, B. O.; Mailand, N.; Gómez, M.; Ramadan, K.; Smits, V. A. J.; Freire, R. ATXN3 Controls DNA Replication and Transcription by Regulating Chromatin Structure. Nucleic Acids Research, 2023, 51(11), 5396–5413. doi: 10.1093/nar/gkad212
  233. Wang, D.; Li, Y.; Deng, X.; Torre, M.; Zhang, Z.; Li, X.; Zhang, W.; Cullion, K.; Kohane, D. S.; Weldon, C. B. An Aptamer-Based Depot System for Sustained Release of Small Molecule Therapeutics. Nature Communications, 2023, 14(1), 2444. doi: 10.1038/s41467-023-37002-0
  234. Xue, X.; Qu, H.; Bo, R.; Zhang, D.; Zhu, Z.; Xiang, B.; Li, L.; Ricci, M.; Pan, C.-X.; Lin, T.-Y.; Li, Y. A Transformable Nanoplatform with Multiple Therapeutic and Immunostimulatory Properties for Treatment of Advanced Cancers. Biomaterials, 2023, 299, 122145. doi: 10.1016/j.biomaterials.2023.122145
  235. Yang, Z.; Xie, H.; Wan, J.; Wang, Y.; Zhang, L.; Zhou, K.; Tang, H.; Zhao, W.; Wang, H.; Song, P.; Zheng, S. A Nanotherapeutic Strategy That Engages Cytotoxic and Immunosuppressive Activities for the Treatment of Cancer Recurrence Following Organ Transplantation. eBioMedicine, 2023, 92, 104594. doi: 10.1016/j.ebiom.2023.104594
  236. Yoshikawa, A. M.; Rangel, A. E.; Zheng, L.; Wan, L.; Hein, L. A.; Hariri, A. A.; Eisenstein, M.; Soh, H. T. A Massively Parallel Screening Platform for Converting Aptamers into Molecular Switches. Nat Commun, 2023, 14(1), 2336. doi: 10.1038/s41467-023-38105-4
  237. De Rosa, L.; Hawala, I.; Di Stasi, R.; Stefania, R.; Capozza, M.; Nava, D.; D’Andrea, L. D. A Chemical Strategy for the Preparation of Multimodified Peptide Imaging Probes. J Org Chem, 2023, 88(7), 4546–4553. doi: 10.1021/acs.joc.3c00014
  238. Hull, S. M.; Lou, J.; Lindsay, C. D.; Navarro, R. S.; Cai, B.; Brunel, L. G.; Westerfield, A. D.; Xia, Y.; Heilshorn, S. C. 3D Bioprinting of Dynamic Hydrogel Bioinks Enabled by Small Molecule Modulators. Sci Adv, 2023, 9(13), eade7880. doi: 10.1126/sciadv.ade7880
  239. Tsai, H.-Y.; Robidillo, C. J. T.; Matharu, G. K.; O’Connor, K.; Cheong, I. T.; Ni, C.; Veinot, J. G. C.; Algar, W. R. Spectrotemporal Characterization of Photoluminescent Silicon Nanocrystals and Their Energy Transfer to Dyes. Nanoscale, 2023, 15(30), 12492–12505. doi: 10.1039/D3NR02461J
  240. Robertus, C. M.; Snyder, S. M.; Curley, S. M.; Murundi, S. D.; Whitman, M. A.; Fischbach, C.; Putnam, D. Selective Accumulation of Near Infrared-Labeled Multivalent Quinidine Copolymers in Tumors Overexpressing P-Glycoprotein: Potential for Noninvasive Diagnostic Imaging. ACS Appl Bio Mater, 2023, 6(8), 3117–3130. doi: 10.1021/acsabm.3c00239
  241. Ozharovskaia, T. A.; Popova, O.;Zubkova, O. V.; Vavilova, I. V.; Pochtovyy, A. A.; Shcheblyakov, D. V.; Gushchin, V.A.; Logunov, D.Yu.; Gintsburg, A.L. Development and characterization of a vector system based on the simian adenovirus type 25. Bulletin of RSMU, 2023, 1, 4-11. doi: 10.24075/brsmu.2023.006
  242. Sivolapova, A. B.; Polivanova, O. B.; Goryunov, D. V.; Chebanova, Y. V.; Fedorova, A. V.; Sotnikova, E. A.; Karabitsina, Y. I.; Benko, N. I.; Mukhina, Z. M.; Anisimova, I. N.; Demurin, Y. N.; Goryunova, S. V. Refinement of Rf1-Gene Localization and Development of the New Molecular Markers for Fertility Restoration in Sunflower. Mol Biol Rep, 2023, 50(9), 7919–7926. doi: 10.1007/s11033-023-08646-4
  243. Grinberg, I.; Ben-Zvi, O.; Adler-Abramovich, L.; Yacoby, I. Peptide Self-Assembly as a Strategy for Facile Immobilization of Redox Enzymes on Carbon Electrodes. Carbon Energy, 2023, e411. doi: 10.1002/cey2.411
  244. Pattadar, D.; Arcidiacono, A.; Beery, D.; Hanson, K.; Saavedra, S. S. Molecular Orientation and Energy Transfer Dynamics of a Metal Oxide Bound Self-Assembled Trilayer. Langmuir, 2023, 39(30), 10670–10679. doi: 10.1021/acs.langmuir.3c01323
  245. Makam, S.; Sétamou, M.; Alabi, O. J.; Day, W.; Cromey, D.; Nwugo, C. Mitigation of Huanglongbing: Implications of a Biologically-Enhanced Nutritional Program on Yield, Pathogen Localization and Host Gene Expression Profiles. Plant Disease, 2023. doi: 10.1094/PDIS-10-22-2336-RE
  246. Peng, Y.-J.; Nanduri, J.; , Wang, N.; Kumar, G.K.; Bindokas, V.;,Paul, B.D.; Chen, X.; Fox, A.P.; Vignane, T.; Filipovic, M.R.; Prabhakar, N.R. Hypoxia sensing requires H2S-dependent persulfidation of olfactory receptor 78. Science Advances, 2023, 9(27), eadf302. doi: 10.1126/sciadv.adf3026
  247. Liang, C.; Huang, W.; Zhang, Y.; Zhang, D.; An, S.; Wu, Q.; Zhao, H.; Wang, C.; Huang, G.; Wei, W.; Liu, J. ImmunoPET Imaging of CD47 with VHH-Derived Tracers in Pancreatic Cancers. Mol. Pharmaceutics, 2023, 20(8), 4184–4195. doi: 10.1021/acs.molpharmaceut.3c00311
  248. Cheng, C.; Zhang, J.; Liu, K.; Xu, Y.; Shen, F.; Han, Y.; Hou, Y.; Zhang, T.; Bai, G. Ginsenoside CK Targeting KEAP1-DGR/Kelch Domain Disrupts the Binding between KEAP1 and NRF2-DLG Motif to Ameliorate Oxidative Stress Damage. Phytomedicine, 2023, 119, 154992. doi: 10.1016/j.phymed.2023.154992
  249. Mauser, A.; Quevedo, D. F.; Zhang, B.; Hernandez, Y.; Berardi, A.; Brown, W.; Lee, S.; Miki, R.; Raymond, J.; Lahann, J.; Greineder, C. F. Enzyme-Based Synthetic Protein Nanoparticles as Colloidal Antioxidants , 2023, 2300007. doi: 10.1002/adtp.202300007
  250. De Pauw, E.; Chen, Y.; De Keersmaecker, H.; De Coninck, E.; De Smet, L.; De Geest, B.; Braeckmans, K.; Vervaet, C.; Vanhoorne, V. Drying Behaviour and Visualization of Surfactants after Co-Spray Drying of Surfactant-Stabilized Aqueous Suspensions. International Journal of Pharmaceutics, 2023, 643, 123231. doi: 10.1016/j.ijpharm.2023.123231
  251. Borner, T.; Tinsley, I. C.; Milliken, B. T.; Doebley, S. A.; Najjar, N. R.; Kerwood, D. J.; De Jonghe, B. C.; Hayes, M. R.; Doyle, R. P. Creation of a Peptide Antagonist of the GFRAL–RET Receptor Complex for the Treatment of GDF15-Induced Malaise. J. Med. Chem., 2023, 66(16), 11237–11249. doi: 10.1021/acs.jmedchem.3c00667
  252. Hu, H.-Y.; Deng, J.-Q.; Wang, Y.-J.; Li, Y.; Meng, X.-L.; Jiang, W.-J.; Wang, F.-S.; Sheng, J.-Z. Cell-Based Assay Approaches for Glycosaminoglycan Synthase High-Throughput Screening: Development and Applications. ACS Chem Biol, 2023, 18(7), 1632–1641. doi: 10.1021/acschembio.3c00244
  253. Breine, A.; Van holsbeeck, K.; Martin, C.; Gonzalez, S.; Mannes, M.; Pardon, E.; Steyaert, J.; Remaut, H.; Ballet, S.; Van der Henst, C. Bypassing the Need for Cell Permeabilization: Nanobody CDR3 Peptide Improves Binding on Living Bacteria. Bioconjugate Chem, 2023, 34(7), 1234–1243. doi: 10.1021/acs.bioconjchem.3c00116
  254. Dai, C.-Y.; Ng, C. C.; Hung, G. C. C.; Kirmes, I.; Hughes, L. A.; Du, Y.; Brosnan, C. A.; Ahier, A.; Hahn, A.; Haynes, C. M.; Rackham, O.; Filipovska, A.; Zuryn, S. ATFS-1 Counteracts Mitochondrial DNA Damage by Promoting Repair over Transcription. Nat Cell Biol, 2023, 25, 1111-1120. doi: 10.1038/s41556-023-01192-y
  255. Rwandamuriye, F. X.; Evans, C. W.; Wylie, B.; Norret, M.; Vitali, B.; Ho, D.; Nguyen, D.; Roper, E. A.; Wang, T.; Hepburn, M. S.; Sanderson, R. W.; Pfirrmann, M.; Fear, V. S.; Forbes, C. A.; Wyatt, K.; Ryan, A. L.; Johns, T. G.; Phillips, M. B.; Hodder, R.; Leslie, C.; Kennedy, B. F.; Zemek, R. M.; Iyer, K. S.; Lesterhuis, W. J. A Surgically Optimized Intraoperative Poly(I:C)-Releasing Hydrogel Prevents Cancer Recurrence. CR Med, 2023, 4(7). doi: 10.1016/j.xcrm.2023.101113
  256. Yang, C., Xu, H., Yang, D.; Xie, Y.; Xiong, M.; Fan, Y.; Liu, X.; Zhang, Y.; Xiao, Y.; Chen, Y.; Zhou, Y.; Song, L.; Wang, C.; Peng, A.; Petersen, R.B.; Chen, H.; Zheng, L.;. A renal YY1-KIM1-DR5 axis regulates the progression of acute kidney injury. Nat Commun, 2023, 14(1), 4261. doi: 10.1038/s41467-023-40036-z
  257. Hossain, K.; Smith, M.; Santoro, S.W. A histological protocol for quantifying the birthrates of specific subtypes of olfactory sensory neurons in mice. STAR Protocols, 2023, 4(3), 102432. doi: 10.1016/j.xpro.2023.102432
  258. Grohme, M.; Frank, O.; Rink, J. Preparing Planarian Cells for High-content Fluorescence Microscopy Using RNA in situ Hybridization and Immunocytochemistry. Methods in Molecular Biology, 2023, 2680, 121-155. doi: 10.1007/978-1-0716-3275-8_8
  259. Amelchenko, E.M.; Bezriadnov, D.V.; Chekhov, O.A.; Ivanova, A.A.; Kedrov, A.V.; Anokhin, K.V.; Lazutkin, A.A.; Enikolopov, G. Cognitive Flexibility Is Selectively Impaired by Radiation and Is Associated with Differential Recruitment of Adult-Born Neurons. The Journal of Neuroscience, 2023, 43(34), 6061-6083. doi: 10.1523/JNEUROSCI.0161-22.2023
  260. Tolmacheva, I.; Beloglazova, Y.; Nazarov, M.; Gagarskikh, O.; Grishko, V. Synthesis and Anticancer Activity of A-Ring-Modified Derivatives of Dihydrobetulin. International Journal of Molecular Sciences, 2023, 24(12), 9863. doi: 10.3390/ijms24129863
  261. Shik, A.V.; Stepanova, I.A.; Doroshenko, I.A.; Podrugina, T.A.; Beklemishev, M.K. Carbocyanine-Based Optical Sensor Array for the Discrimination of Proteins and Rennet Samples Using Hypochlorite Oxidation. Sensors (Basel), 2023, 23(9), 4299. doi: 10.3390/s23094299
  262. Girich, E.V.; Trinh, P.T.H; Nesterenko, L.E.; Popov, R.S.; Kim, N.Y.; Rasin, A.B.; Menchinskaya, E.S.; Kuzmich, A.S.; Chingizova, E.A.; Minin, A.S.; Ngoc, N.T.D.; Van, T.T.T.; Yurchenko, E.A.; Yurchenko, A.N.; Berdyshev, D.V. Absolute Stereochemistry and Cytotoxic Effects of Vismione E from Marine Sponge-Derived Fungus Aspergillus sp. 1901NT-1.2.2. International Journal of Molecular Sciences, 2023, 24(9), 8150. doi: 10.3390/ijms24098150
  263. Moiseeva, N.; Eroshenko, D.; Laletina, L.; Rybalkina, E.; Susova, O.; Karamysheva, A.; Tolmacheva, I.; Nazarov, M.; Grishko, V. The Molecular Mechanisms of Oleanane Aldehyde-β-enone Cytotoxicity against Doxorubicin-Resistant Cancer Cells. Biology (Basel), 2023, 12(3), 415. doi: 10.3390/biology12030415
  264. Gileva, A.; Trushina, D.; Yagolovich, A.; Gasparian, M.; Kurbanova, L.; Smirnov, I.; Burov, S.; Markvicheva, E. Doxorubicin-Loaded Polyelectrolyte Multilayer Capsules Modified with Antitumor DR5-Specific TRAIL Variant for Targeted Drug Delivery to Tumor Cells. Nanomaterials, 2023, 13(5), 902. doi: 10.3390/nano13050902
  265. Psotta, C.; Chaturvedi, V.; Gonzalez-Martinez, J.F.; Sotres, J.; Falk, M. Portable Prussian Blue-Based Sensor for Bacterial Detection in Urine. Sensors, 2023, 23(1), 388. doi: 10.3390/s23010388

2022

  1. Boffoli, D.; Bellato, F.; Avancini, G.; Gurnani, P.; Yilmaz, G.; Romero, M.; Robertson, S.; Moret, F.; Sandrelli, F.; Caliceti, P.; Salmaso, S.; Cámara, M.; Mantovani, G.; Mastrotto, F. Tobramycin-Loaded Complexes to Prevent and Disrupt Pseudomonas Aeruginosa Biofilms. Drug Deliv. and Transl. Res., 2022, 12(8), 1788–1810. doi: 10.1007/s13346-021-01085-3
  2. Kuiper, E. F. E.; Gallardo, P.; Bergsma, T.; Mari, M.; Kolbe Musskopf, M.; Kuipers, J.; Giepmans, B. N. G.; Steen, A.; Kampinga, H. H.; Veenhoff, L. M.; Bergink, S. The Chaperone DNAJB6 Surveils FG-Nucleoporins and Is Required for Interphase Nuclear Pore Complex Biogenesis. Nat Cell Biol, 2022, 24(11), 1584–1594. doi: 10.1038/s41556-022-01010-x
  3. Melnikov, N. P.; Bolshakov, F. V.; Frolova, V. S.; Skorentseva, K. V.; Ereskovsky, A. V.; Saidova, A. A.; Lavrov, A. I. Tissue Homeostasis in Sponges: Quantitative Analysis of Cell Proliferation and Apoptosis. Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, 2022, 338(6), 360–381. doi: 10.1002/jez.b.23138
  4. Maltsev, D. I.; Mellanson, K. A.; Belousov, V. V.; Enikolopov, G. N.; Podgorny, O. V. The Bioavailability Time of Commonly Used Thymidine Analogues after Intraperitoneal Delivery in Mice: Labeling Kinetics in Vivo and Clearance from Blood Serum. Histochem Cell Biol, 2022, 157(2), 239–250. doi: 10.1007/s00418-021-02048-y
  5. Yan, Y.; Zhou, L.; Sun, Z.; Song, D.; Cheng, Y. Targeted and Intracellular Delivery of Protein Therapeutics by a Boronated Polymer for the Treatment of Bone Tumors. Bioactive Materials, 2022, 7, 333–340. doi: 10.1016/j.bioactmat.2021.05.041
  6. Emelyanova, M.; Pokataev, I.; Shashkov, I.; Kopantseva, E.; Lyadov, V.; Heydarov, R.; Mikhailovich, V. TYMS 3′-UTR Polymorphism: A Novel Association with FOLFIRINOX-Induced Neurotoxicity in Pancreatic Cancer Patients. Pharmaceutics, 2022, 14(1), 77. doi: 10.3390/pharmaceutics14010077
  7. Fischer, N. G.; Kobe, A. C.; Dai, J.; He, J.; Wang, H.; Pizarek, J. A.; De Jong, D. A.; Ye, Z.; Huang, S.; Aparicio, C. Tapping Basement Membrane Motifs: Oral Junctional Epithelium for Surface-Mediated Soft Tissue Attachment to Prevent Failure of Percutaneous Devices. Acta Biomaterialia, 2022, 141, 70–88. doi: 10.1016/j.actbio.2021.12.030
  8. Santos-Coquillat, A.; González, M. I.; Clemente-Moragón, A.; González-Arjona, M.; Albaladejo-García, V.; Peinado, H.; Muñoz, J.; Ximénez Embún, P.; Ibañez, B.; Oliver, E.; Desco, M.; Salinas, B. Goat Milk Exosomes As Natural Nanoparticles for Detecting Inflammatory Processes By Optical Imaging. Small, 2022, 18(6), 2105421. doi: 10.1002/smll.202105421
  9. Zuo, Z.; He, L.; Duan, X.; Peng, Z.; Han, J. Glycyrrhizic Acid Exhibits Strong Anticancer Activity in Colorectal Cancer Cells via SIRT3 Inhibition. Bioengineered, 2022, 13(2), 2720–2731. doi: 10.1080/21655979.2021.2001925
  10. Lee, J. H.; Song, J.; Kim, I. G.; You, G.; Kim, H.; Ahn, J.-H.; Mok, H. Exosome-Mediated Delivery of Transforming Growth Factor-β Receptor 1 Kinase Inhibitors and Toll-like Receptor 7/8 Agonists for Combination Therapy of Tumors. Acta Biomaterialia, 2022, 141, 354–363. doi: 10.1016/j.actbio.2022.01.005
  11. White, M. J.; Raczy, M. M.; Budina, E.; Yuba, E.; Solanki, A.; Shim, H.-N.; Zhang, Z. J.; Gray, L. T.; Cao, S.; Alpar, A. T.; Hubbell, J. A. Engineered Collagen-Targeting Therapeutics Reverse Lung and Kidney Fibrosis in Mice. bioRxiv, 2022, preprint. doi: 10.1101/2022.01.04.474747
  12. Alshanski, I.; Shitrit, A.; Sukhran, Y.; Unverzagt, C.; Hurevich, M.; Yitzchaik, S. Effect of Interfacial Properties on Impedimetric Biosensing of the Sialylation Process with a Biantennary N-Glycan-Based Monolayer. Langmuir, 2022, 38(2), 849–855. doi: 10.1021/acs.langmuir.1c02995
  13. Selnihhin, D.; Mortensen, K. I.; Larsen, J. B.; Simonsen, J. B.; Pedersen, F. S. DNA Origami Calibrators for Counting Fluorophores on Single Particles by Flow Cytometry. Small Methods, 2022, 6(3), 2101364. doi: 10.1002/smtd.202101364
  14. Yan, Y.; Chen, B.; Yin, Q.; Wang, Z.; Yang, Y.; Wan, F.; Wang, Y.; Tang, M.; Xia, H.; Chen, M.; Liu, J.; Wang, S.; Zhang, Q.; Wang, Y. Dissecting Extracellular and Intracellular Distribution of Nanoparticles and Their Contribution to Therapeutic Response by Monochromatic Ratiometric Imaging. Nat Commun, 2022, 13(1), 2004. doi: 10.1038/s41467-022-29679-6
  15. Elangovan, A.; Suresh, D.; Tarim, A. O.; Upendran, A.; Kannan, R. Controlled Assembly of Gold and Albumin Nanoparticles to Form Hybrid Multimeric Nanomaterials. Polymers for Advanced Technologies, 2022, 33(2), 566–575. doi: 10.1002/pat.5538
  16. Kesarwani, V.; Walker, J. A.; Henderson, E. C.; Huynh, G.; McLiesh, H.; Graham, M.; Wieringa, M.; Banaszak Holl, M. M.; Garnier, G.; Corrie, S. R. Column Agglutination Assay Using Polystyrene Microbeads for Rapid Detection of Antibodies against SARS-CoV-2. ACS Appl. Mater. Interfaces, 2022, 14(2), 2501–2509. doi: 10.1021/acsami.1c17859
  17. Arranz-Gibert, P.; Vanderschuren, K.; Haimovich, A.; Halder, A.; Gupta, K.; Rinehart, J.; Isaacs, F. J. Chemoselective Restoration of Para-Azido-Phenylalanine at Multiple Sites in Proteins. Cell Chemical Biology, 2022, 29(6), 1046-1052.e4. doi: 10.1016/j.chembiol.2021.12.002
  18. Ksenofontov, A. A.; Bocharov, P. S.; Ksenofontova, K. V.; Antina, E. V. Water-Soluble BODIPY-Based Fluorescent Probe for BSA and HSA Detection. Journal of Molecular Liquids, 2022, 345, 117031. doi: 10.1016/j.molliq.2021.117031
  19. Tähtinen, V.; Gulumkar, V.; Maity, S. K.; Yliperttula, A.-M.; Siekkinen, S.; Laine, T.; Lisitsyna, E.; Haapalehto, I.; Viitala, T.; Vuorimaa-Laukkanen, E.; Yliperttula, M.; Virta, P. Assembly of Bleomycin Saccharide-Decorated Spherical Nucleic Acids. Bioconjugate Chem., 2022, 33(1), 206–218. doi: 10.1021/acs.bioconjchem.1c00539
  20. Wei, W.; Zhang, D.; Wang, C.; Zhang, Y.; An, S.; Chen, Y.; Huang, G.; Liu, J. Annotating CD38 Expression in Multiple Myeloma with [18F]F–Nb1053. Mol. Pharmaceutics, 2022, 19(10), 3502–3510. doi: 10.1021/acs.molpharmaceut.1c00733
  21. Kafle, C. M.; Anderson, A. Y.; Prakash, A.; Swedik, S.; Bridge, E. An Adenovirus Early Region 4 Deletion Mutant Induces G2/M Arrest via ATM Activation and Reduces Expression of the Mitotic Marker Phosphorylated (Ser10) Histone 3. Virology, 2022, 565, 1–12. doi: 10.1016/j.virol.2021.09.006
  22. Mohammad-Beigi, H.; Zanganeh, M.; Scavenius, C.; Eskandari, H.; Farzadfard, A.; Shojaosadati, S. A.; Enghild, J. J.; Otzen, D. E.; Buell, A. K.; Sutherland, D. S. A Protein Corona Modulates Interactions of α-Synuclein with Nanoparticles and Alters the Rates of the Microscopic Steps of Amyloid Formation. ACS Nano, 2022, 16(1), 1102–1118. doi: 10.1021/acsnano.1c08825
  23. Schotman, M. J. G.; Fransen, P.-P.; Song, J.; W. Dankers, P. Y. Tuning the Affinity of Amphiphilic Guest Molecules in a Supramolecular Polymer Transient Network. RSC Advances, 2022, 12(22), 14052–14060. doi: 10.1039/D2RA00346E
  24. Reyes, A. F.; Goldusky, J.; Bhimalli, P.; Marzo, A. L.; Schneider, J. R. Tracking Fluorescently Labeled IL-15 and Anti-PD-1 in the Tumor Microenvironment and Draining Lymph Nodes. Journal of Immunological Methods, 2022, 505, 113253. doi: 10.1016/j.jim.2022.113253.
  25. Krausova, K.; Charousova, M.; Kratochvil, Z.; Takacsova, P.; Tesarova, B.; Sivak, L.; Peskova, M. K.; Sukupova, M.; Zivotska, H.; Makovicky, P.; Yamashita, I.; Okamoto, N.; Hynek, D.; Haddad, Y.; Pekarik, V.; Rex, S.; Heger, Z. Toward Understanding the Kinetics of Disassembly of Ferritins of Varying Origin and Subunit Composition. Applied Materials Today, 2022, 28, 101535. doi: 10.1016/j.apmt.2022.101535
  26. Liu, X.; Ren, X.; Zhou, L.; Liu, K.; Deng, L.; Qing, Q.; Li, J.; Zhi, F.; Li, M. Tollip Orchestrates Macrophage Polarization to Alleviate Intestinal Mucosal Inflammation. Journal of Crohn’s and Colitis, 2022, 16(7), 1151–1167. doi: 10.1093/ecco-jcc/jjac019
  27. Kim, Y. M.; Lee, K.; Lee, Y.; Yang, K.; Choe, D.; Roh, Y. H. Thermoresponsive Semi-Interpenetrating Gelatin-Alginate Networks for Encapsulation and Controlled Release of Scent Molecules. International Journal of Biological Macromolecules, 2022, 208, 1096–1105. doi: 10.1016/j.ijbiomac.2022.03.185
  28. Kalinovsky, D. V.; Kibardin, A. V.; Kholodenko, I. V.; Svirshchevskaya, E. V.; Doronin, I. I.; Konovalova, M. V.; Grechikhina, M. V.; Rozov, F. N.; Larin, S. S.; Deyev, S. M.; Kholodenko, R. V. Therapeutic Efficacy of Antibody-Drug Conjugates Targeting GD2-Positive Tumors. J Immunother Cancer, 2022, 10(5), e004646. doi: 10.1136/jitc-2022-004646
  29. Sposito, B.; Mambu, J.; Gwilt, K. B.; Spinelli, L.; Andreeva, N.; Galland, F.; Naquet, P.; Mitsialis, V.; Thiagarajah, J. R.; Snapper, S. B.; Broggi, A.; Zanoni, I. Type III Interferons Induce Pyroptosis in Gut Epithelial Cells and Delay Tissue Restitution upon Acute Intestinal Injury. bioRxiv, 2022, preprint. doi: 10.1101/2022.03.04.482997
  30. Cierzniak, A.; Kaliszewski, K.; Małodobra-Mazur, M. The Preliminary Evaluation of Epigenetic Modifications Regulating the Expression of IL10 in Insulin-Resistant Adipocytes. Genes, 2022, 13(2), 294. doi: 10.3390/genes13020294
  31. Han, G.; Kim, H.; Kim, D. E.; Ahn, Y.; Kim, J.; Jang, Y. J.; Kim, K.; Yang, Y.; Kim, S. H. The Potential of Bovine Colostrum-Derived Exosomes to Repair Aged and Damaged Skin Cells. Pharmaceutics, 2022, 14(2), 307. doi: 10.3390/pharmaceutics14020307
  32. Zhang, W.; Zhang, S.; Chen, C.; Liu, N.; Yang, D.; Wang, P.; Ren, F. The Internalization Mechanisms and Trafficking of the Pea Albumin in Caco-2 Cells. International Journal of Biological Macromolecules, 2022, 217, 111–119. doi: 10.1016/j.ijbiomac.2022.06.149
  33. Ikonnikova, A.; Rodina, T.; Dmitriev, A.; Melnikov, E.; Kazakov, R.; Nasedkina, T. The Influence of the CES1 Genotype on the Pharmacokinetics of Enalapril in Patients with Arterial Hypertension. Journal of Personalized Medicine, 2022, 12(4), 580. doi: 10.3390/jpm12040580
  34. Mishyn, V.; Hugo, A.; Rodrigues, T.; Aspermair, P.; Happy, H.; Marques, L.; Hurot, C.; Othmen, R.; Bouchiat, V.; Boukherroub, R.; Knoll, W.; Szunerits, S. The Holy Grail of Pyrene-Based Surface Ligands on the Sensitivity of Graphene-Based Field Effect Transistors. Sens. Diagn., 2022, 1(2), 235–244.. doi: 10.1039/D1SD00036E
  35. Borkosky, S. S.; Fassolari, M.; Campos-León, K.; Rossi, A. H.; Salgueiro, M.; Pascuale, C.; Martínez, R. P.; Gaston, K.; Gay, G. de P. The Guardian of the Genome Meets a Viral Master Gene Regulator at a Biomolecular Condensate. bioRxiv, 2022, preprint. doi: 10.1101/2022.02.09.479752
  36. Gaglia, G.; Kabraji, S.; Rammos, D.; Dai, Y.; Verma, A.; Wang, S.; Mills, C.; Chung, M.; Bergholz, J.; Coy, S.; Lin, J.-R.; Jeselsohn, R.; Metzger, O.; Winer, E.; Dillon, D.; Zhao, J.; Sorger, P.; Santagata, S. Temporal and Spatial Topography of Cell Proliferation in Cancer. Nature Cell Biology, 2022, 24, 316–326. doi: 10.1038/s41556-022-00860-9
  37. Petit, P.-F.; Bombart, R.; Desimpel, P.-H.; Naulaerts, S.; Thouvenel, L.; Collet, J.-F.; Van Den Eynde, B. J.; Zhu, J. T Cell–Mediated Targeted Delivery of Anti–PD-L1 Nanobody Overcomes Poor Antibody Penetration and Improves PD-L1 Blocking at the Tumor Site. Cancer Immunology Research, 2022, 10(5), 713–727. doi: 10.1158/2326-6066.CIR-21-0801
  38. Zhdanov, G. A.; Gribanyov, D. A.; Gambaryan, A. S.; Kukushkin, V. I.; Zavyalova, E. G. Using a Biosensor Based on Surface-Enhanced Raman Scattering to Identify Influenza Viruses in Biological Fluids. Bull. Russ. Acad. Sci. Phys., 2022, 86(4), 434–437. doi: 10.3103/S1062873822040293
  39. Ma, X.; Bai, Y.; Liu, K.; Han, Y.; Zhang, J.; Liu, Y.; Hou, X.; Hao, E.; Hou, Y.; Bai, G. Ursolic Acid Inhibits the Cholesterol Biosynthesis and Alleviates High Fat Diet-Induced Hypercholesterolemia via Irreversible Inhibition of HMGCS1 in Vivo. Phytomedicine, 2022, 103, 154233. doi: 10.1016/j.phymed.2022.154233
  40. Sokolova, V.; Ebel, J.-F.; Kollenda, S.; Klein, K.; Kruse, B.; Veltkamp, C.; Lange, C. M.; Westendorf, A. M.; Epple, M. Uptake of Functional Ultrasmall Gold Nanoparticles in 3D Gut Cell Models. Small, 2022, 18(31), 2201167. doi: 10.1002/smll.202201167
  41. Schmitz, V.; Ochoa, M. T.; Teles, R. M. B.; Jo, E.-K. Editorial: Strategies Played by Immune Cells and Mycobacteria in the Battle between Antimicrobial Activity and Bacterial Survival. Front. Immunol., 2022, 13. doi: 10.3389/fimmu.2022.869692
  42. Chumakov, D.; Kichkailo, A.; Zamay, G.; Burov, A.; Khlebtsov, N. Synthesis and Characteristics of Fluorescent Red-Emitting DNA-Templated Silver Nanoclusters Based on Aptamer Selected to Lung Cancer. Computational Biophysics and Nanobiophotonics: SPIE, 2022, 12194, 245–250. doi: 10.1117/12.2626120
  43. Latorre, R.; Ramírez-Garcia, P. D.; Hegron, A.; Grace, J. L.; Retamal, J. S.; Shenoy, P.; Tran, M.; Aurelio, L.; Flynn, B.; Poole, D. P.; Klein-Cloud, R.; Jensen, D. D.; Davis, T. P.; Schmidt, B. L.; Quinn, J. F.; Whittaker, M. R.; Veldhuis, N. A.; Bunnett, N. W. Sustained Endosomal Release of a Neurokinin-1 Receptor Antagonist from Nanostars Provides Long-Lasting Relief of Chronic Pain. Biomaterials, 2022, 285, 121536. doi: 10.1016/j.biomaterials.2022.121536
  44. Tang, W.; Panja, S.; Jogdeo, C. M.; Tang, S.; Yu, A.; Oupický, D. Study of Renal Accumulation of Targeted Polycations in Acute Kidney Injury. Biomacromolecules, 2022, 23(5), 2064–2074. doi: 10.1021/acs.biomac.2c00079
  45. Müller, C.; Gleixner, J.; Tahk, M.-J.; Kopanchuk, S.; Laasfeld, T.; Weinhart, M.; Schollmeyer, D.; Betschart, M. U.; Lüdeke, S.; Koch, P.; Rinken, A.; Keller, M. Structure-Based Design of High-Affinity Fluorescent Probes for the Neuropeptide Y Y1 Receptor. J. Med. Chem., 2022, 65(6), 4832–4853. doi: 10.1021/acs.jmedchem.1c02033
  46. Alakesh, A.; Jothiprakasam, T.; Raghavan, J. V.; Jhunjhunwala, S. Sterile Inflammation Alters Neutrophil Kinetics in Mice. Journal of Leukocyte Biology, 2022, 112(3), 395–409. doi: 10.1002/JLB.1A0321-132RR
  47. Li, W.; Hadjigol, S.; Mazo, A. R.; Holden, J.; Lenzo, J.; Shirbin, S. J.; Barlow, A.; Shabani, S.; Huang, T.; Reynolds, E. C.; Qiao, G. G.; O’Brien-Simpson, N. M. Star-Peptide Polymers Are Multi-Drug-Resistant Gram-Positive Bacteria Killers. ACS Appl. Mater. Interfaces, 2022, 14(22), 25025–25041. doi: 10.1021/acsami.1c23734
  48. Drexel, M.; Rahimi, S.; Sperk, G. Silencing of Hippocampal Somatostatin Interneurons Induces Recurrent Spontaneous Limbic Seizures in Mice. Neuroscience, 2022, 487, 155–165. doi: 10.1016/j.neuroscience.2022.02.007
  49. Liu, H.; Hu, Z.; Chen, H.; Yan, Y.; Le, Z.; Wei, C.; Cao, W.; Chen, T.; Chen, Y.; Liu, L. Self-Degradable Poly(β-Amino Ester)s Promote Endosomal Escape of Antigen and Agonist. Journal of Controlled Release, 2022, 345, 91–100. doi: 10.1016/j.jconrel.2022.03.006
  50. Li, M.; Huang, J.; Ma, M.; Shi, X.; Li, L. Selective Enrichment of Sialylglycopeptides Enabled by Click Chemistry and Dynamic Covalent Exchange. Anal. Chem., 2022, 94(18), 6681–6688.. doi: 10.1021/acs.analchem.1c05158
  51. Nonaka, S.; Kadowaki, T.; Nakanishi, H. Secreted Gingipains from Porphyromonas Gingivalis Increase Permeability in Human Cerebral Microvascular Endothelial Cells through Intracellular Degradation of Tight Junction Proteins. Neurochemistry International, 2022, 154, 105282. doi: 10.1016/j.neuint.2022.105282
  52. Pletnev, P. I.; Shulenina, O.; Evfratov, S.; Treshin, V.; Subach, M. F.; Serebryakova, M. V.; Osterman, I. A.; Paleskava, A.; Bogdanov, A. A.; Dontsova, O. A.; Konevega, A. L.; Sergiev, P. V. Ribosomal Protein S18 Acetyltransferase RimI Is Responsible for the Acetylation of Elongation Factor Tu. Journal of Biological Chemistry, 2022, 298(5), 101914. doi: 10.1016/j.jbc.2022.101914
  53. Kuwabara, J. T.; Hara, A.; Heckl, J. R.; Peña, B.; Bhutada, S.; DeMaris, R.; Ivey, M. J.; DeAngelo, L. P.; Liu, X.; Park, J.; Jahansooz, J. R.; Mestroni, L.; McKinsey, T. A.; Apte, S. S.; Tallquist, M. D. Regulation of Extracellular Matrix Composition by Fibroblasts during Perinatal Cardiac Maturation. Journal of Molecular and Cellular Cardiology, 2022, 169, 84–95. doi: 10.1016/j.yjmcc.2022.05.003
  54. Ji, F.; Wang, S.; Shao, S.; Sarkar, P.; Xue, M. Real-Time Analysis of AKT Signaling Activities at Single-Cell Resolution Using Cyclic Peptide-Based Probes. Biomedical Engineering Technologies: Methods in Molecular Biology, 2022, 2394, 65–80. doi: 10.1007/978-1-0716-1811-0_5
  55. Monakhova, M. V.; Kubareva, E. A.; Kolesnikov, K. K.; Anashkin, V. A.; Kosaretskiy, E. M.; Zvereva, M. I.; Romanova, E. A.; Friedhoff, P.; Oretskaya, T. S.; Zatsepin, T. S. Reactive Acrylamide-Modified DNA Traps for Accurate Cross-Linking with Cysteine Residues in DNA–Protein Complexes Using Mismatch Repair Protein MutS as a Model. Molecules, 2022, 27(8), 2438. doi: 10.3390/molecules27082438
  56. Michielsen, C. M. S.; van Aalen, E. A.; Merkx, M. Ratiometric Bioluminescent Zinc Sensor Proteins to Quantify Serum and Intracellular Free Zn2+. ACS Chem. Biol., 2022, 17(6), 1567–1576. doi: 10.1021/acschembio.2c00227
  57. Fu, H.-J.; Su, R.; Luo, L.; Chen, Z.-J.; Sørensen, T. J.; Hildebrandt, N.; Xu, Z.-L. Rapid and Wash-Free Time-Gated FRET Histamine Assays Using Antibodies and Aptamers. ACS Sens., 2022, 7(4), 1113–1121. doi: 10.1021/acssensors.2c00085
  58. Son, T.; Cho, Y.-J.;Lee, H.; Cho, M.Y.; Goh, B.; Kim, H.M.; Phan, H.Th.N.; Cho, S.-H.; Park, Y.-J.; Park, H.S. Quantitative Assessment of the Size-dependent Whole-body to Cellular Biodistribution of Fine Particulate Matters Following Inhalation by Fluorescence Imaging. Research Square, 2022, preprint. doi: 10.21203/rs.3.rs-1230726/v1
  59. Alì, A.; Leibowitz, D.; Bhatt, N.; Doubrovin, M.; Bates-Pappas, G. E.; Taub, R. N.; McKiernan, J. M.; Mintz, A.; Molotkov, A. Preliminary Efficacy of [90Y] DOTA-Biotin-Avidin Radiotherapy against Non-Muscle Invasive Bladder Cancer. Research Square, 2022, preprint. doi: 10.21203/rs.3.rs-1559077/v1
  60. Najer, A.; Blight, J.; Ducker, C. B.; Gasbarri, M.; Brown, J. C.; Che, J.; Høgset, H.; Saunders, C.; Ojansivu, M.; Lu, Z.; Lin, Y.; Yeow, J.; Rifaie-Graham, O.; Potter, M.; Tonkin, R.; Penders, J.; Doutch, J. J.; Georgiadou, A.; Barriga, H. M. G.; Holme, M. N.; Cunnington, A. J.; Bugeon, L.; Dallman, M. J.; Barclay, W. S.; Stellacci, F.; Baum, J.; Stevens, M. M. Potent Virustatic Polymer–Lipid Nanomimics Block Viral Entry and Inhibit Malaria Parasites In Vivo. ACS Cent. Sci., 2022, 8(9), 1238–1257. doi: 10.1021/acscentsci.1c01368
  61. Liu, H.; Wu, S.; Lee, H.; Baudo, G.; Massaro, M.; Zhang, A.; Hamilton, D. J.; Blanco, E. Polymer-Functionalized Mitochondrial Transplantation to Plaque Macrophages as a Therapeutic Strategy Targeting Atherosclerosis. Advanced Therapeutics, 2022, 5(5), 2100232. doi: 10.1002/adtp.202100232
  62. Yang, Y.; Kozlovskaya, V.; Zhang, Z.; Xing, C.; Zaharias, S.; Dolmat, M.; Qian, S.; Zhang, J.; Warram, J. M.; Yang, E. S.; Kharlampieva, E. Poly(N-Vinylpyrrolidone)-Block-Poly(Dimethylsiloxane)-Block-Poly(N-Vinylpyrrolidone) Triblock Copolymer Polymersomes for Delivery of PARP1 SiRNA to Breast Cancers. ACS Appl. Bio Mater., 2022, 5(4), 1670–1682. doi: 10.1021/acsabm.2c00063
  63. Hernández-Coronado, M.; Dias Araujo, P. C.; Ip, P.-L.; Nunes, C. O.; Rahni, R.; Wudick, M. M.; Lizzio, M. A.; Feijó, J. A.; Birnbaum, K. D. Plant Glutamate Receptors Mediate a Bet-Hedging Strategy between Regeneration and Defense. Developmental Cell, 2022, 57(4), 451-465.e6. doi: 10.1016/j.devcel.2022.01.013
  64. Maingret, V.; Chartier, C.; Six, J.-L.; Schmitt, V.; Héroguez, V. Pickering Emulsions Stabilized by Biodegradable Dextran-Based Nanoparticles Featuring Enzyme Responsiveness and Co-Encapsulation of Actives. Carbohydrate Polymers, 2022, 284, 119146. doi: 10.1016/j.carbpol.2022.119146
  65. Chetverikov, P. E.; Rector, B. G.; Tonkel, K.; Dimitri, L.; Cheglakov, D. S.; Romanovich, A. E.; Amrine, J. Phylogenetic Position of a New Trisetacus Mite Species (Nalepellidae) Destroying Seeds of North American Junipers and New Hypotheses on Basal Divergence of Eriophyoidea. Insects, 2022, 13(2), 201. doi: 10.3390/insects13020201
  66. Klöcker, N.; Weissenboeck, F. P.; van Dülmen, M.; Špaček, P.; Hüwel, S.; Rentmeister, A. Photocaged 5′ Cap Analogues for Optical Control of MRNA Translation in Cells. Nat. Chem., 2022, 14(8), 905–913. doi: 10.1038/s41557-022-00972-7
  67. Khadria, A.; Paavola, C. D.; Maslov, K.; Valenzuela, F. A.; Sperry, A. E.; Cox, A. L.; Cao, R.; Shi, J.; Brown-Augsburger, P. L.; Lozano, E.; Blankenship, R. L.; Majumdar, R.; Bradley, S. A.; Beals, J. M.; Oladipupo, S. S.; Wang, L. V. Photoacoustic Imaging Reveals Mechanisms of Rapid-Acting Insulin Formulations Dynamics at the Injection Site. Molecular Metabolism, 2022, 62, 101522. doi: 10.1016/j.molmet.2022.101522
  68. Vellecco, V.; Panza, E.; Bibli, S.-I.; Casillo, G. M.; Raucci, F.; Manzo, O. L.; Smimmo, M.; Villani, R.; Cavezza, M. R.; Fleming, I.; d’Emmanuele di Villa Bianca, R.; Maione, F.; Cirino, G.; Bucci, M. Phosphodiesterases S-Sulfhydration Contributes to Human Skeletal Muscle Function. Pharmacological Research, 2022, 177, 106108. doi: 10.1016/j.phrs.2022.106108
  69. Utterström, J.; Barriga, H. M. G.; Holme, M. N.; Selegård, R.; Stevens, M. M.; Aili, D. Peptide-Folding Triggered Phase Separation and Lipid Membrane Destabilization in Cholesterol-Rich Lipid Vesicles. Bioconjugate Chem., 2022, 33(4), 736–746. doi: 10.1021/acs.bioconjchem.2c00115
  70. He, Y.; Hong, C.; Fletcher, S. J.; Berger, A. G.; Sun, X.; Yang, M.; Huang, S.; Belcher, A. M.; Irvine, D. J.; Li, J.; Hammond, P. T. Peptide-Based Cancer Vaccine Delivery via the STINGΔTM-CGAMP Complex. Advanced Healthcare Materials, 2022, 11(15), 2200905. doi: 10.1002/adhm.202200905
  71. Li, Y.; Lofchy, L.; Wang, G.; Gaikwad, H.; Fujita, M.; Simberg, D. PEGylated Liposomes Accumulate in the Areas Relevant to Skin Toxicities via Passive Extravasation across “Leaky” Endothelium. ACS Nano, 2022, 16(4), 6349–6358. doi: 10.1021/acsnano.2c00423
  72. Kim, S.; Heo, R.; Song, S. H.; Song, K.-H.; Shin, J. M.; Oh, S. J.; Lee, H.-J.; Chung, J. E.; Park, J. H.; Kim, T. W. PD-L1 SiRNA–Hyaluronic Acid Conjugate for Dual-Targeted Cancer Immunotherapy. Journal of Controlled Release, 2022, 346, 226–239. doi: 10.1016/j.jconrel.2022.04.023
  73. Travanut, A.; F. Monteiro, P.; Smith, S.; M. Howdle, S.; M. Grabowska, A.; Kellam, B.; R. Meier, M. A.; Alexander, C. Passerini Chemistries for Synthesis of Polymer Pro-Drug and Polymersome Drug Delivery Nanoparticles. Journal of Materials Chemistry B, 2022, 10(20), 3895–3905. doi: 10.1039/D2TB00045H
  74. Zhao, P.; Liu, S.; Koriath, A. T.; Gao, X. Partial Magneto-Endosomalysis for Cytosolic Delivery of Antibodies. Bioconjugate Chem., 2022, 33(2), 363–368. doi: 10.1021/acs.bioconjchem.1c00598
  75. Conod, A.; Silvano, M.; Ruiz i Altaba, A. On the Origin of Metastases: Induction of pro-Metastatic States after Impending Cell Death via ER Stress, Reprogramming, and a Cytokine Storm. Cell Reports, 2022, 38(10), 110490. doi: 10.1016/j.celrep.2022.110490
  76. Park, J. S.; Lim, Y. G.; Park, K. Novel Bidentate β-Glutamic Acid-Based Bone-Targeting Agents for in Vivo Bone Imaging. Journal of Industrial and Engineering Chemistry, 2022, 110, 471–478. doi: 10.1016/j.jiec.2022.03.021
  77. Li, C.; Yang, Q.; Chen, Z.; Qiu, Y.; Du, Y.; Wang, R.; He, Q.; Yang, J.; Zhen, H.; Kang, L. Noninvasive Evaluation of Multidrug Resistance via Imaging of ABCG2/BCRP Multidrug Transporter in Lung Cancer Xenograft Models. Mol. Pharmaceutics, 2022, 19(10), 3521–3529. doi: 10.1021/acs.molpharmaceut.1c00939
  78. Budke, B.; Zhong, A.; Sullivan, K.; Park, C.; Gittin, D. I.; Kountz, T. S.; Connell, P. P. Noncanonical NF-ΚB Factor P100/P52 Regulates Homologous Recombination and Modulates Sensitivity to DNA-Damaging Therapy. Nucleic Acids Research, 2022, 50(11), 6251–6263. doi: 10.1093/nar/gkac491
  79. Massó-Vallés, D.; Beaulieu, M.-E.; Jauset, T.; Giuntini, F.; Zacarías-Fluck, M. F.; Foradada, L.; Martínez-Martín, S.; Serrano, E.; Martín-Fernández, G.; Casacuberta-Serra, S.; Castillo Cano, V.; Kaur, J.; López-Estévez, S.; Morcillo, M. Á.; Alzrigat, M.; Mahmoud, L.; Luque-García, A.; Escorihuela, M.; Guzman, M.; Arribas, J.; Serra, V.; Larsson, L.-G.; Whitfield, J. R.; Soucek, L. MYC Inhibition Halts Metastatic Breast Cancer Progression by Blocking Growth, Invasion, and Seeding. Cancer Research Communications, 2022, 2(2), 110–130. doi: 10.1158/2767-9764.CRC-21-0103
  80. Hagemans, I. M.; Wierstra, P. J.; Steuten, K.; Molkenboer-Kuenen, J. D. M.; van Dalen, D.; ter Beest, M.; van der Schoot, J. M. S.; Ilina, O.; Gotthardt, M.; Figdor, C. G.; Scheeren, F. A.; Heskamp, S.; Verdoes, M. Multiscale Imaging of Therapeutic Anti-PD-L1 Antibody Localization Using Molecularly Defined Imaging Agents. Journal of Nanobiotechnology, 2022, 20(1), 64. doi: 10.1186/s12951-022-01272-5
  81. Santiana, J.J. ; Sawant, S.S.; Gomez, N.; Rouge, J. L. Multi-Layered Stimuli Responsive DNA Micelles for the Stepwise Controlled Release of Small Molecules. Journal of Materials Chemistry B, 2022, 10(37), 7518–7526. doi: 10.1039/D1TB02722K
  82. Son, T.; Cho, Y.-J.; Lee, H.; Cho, M. Y.; Goh, B.; Kim, H. M.; Hoa, P. T. N.; Cho, S.-H.; Park, Y.-J.; Park, H. S.; Hong, K. S. Monitoring in Vivo Behavior of Size-Dependent Fluorescent Particles as a Model Fine Dust. Journal of Nanobiotechnology, 2022, 20(1), 227. doi: 10.1186/s12951-022-01419-4
  83. Wu, F.; Gardinier, T. C.; Turker, M. Z.; Chen, F.; Chen, P.-M.; Venkatesan, A. M.; Patel, V.; Adams, G. P.; Bradbury, M. S.; Wiesner, U. B.; Germano, G.; Ma, K. Molecular Engineering of Surface Functional Groups Enabling Clinical Translation of Nanoparticle–Drug Conjugates. Chem. Mater., 2022, 34(12), 5344–5355. doi: 10.1021/acs.chemmater.1c04447
  84. Hong, C.; Alser, O.; Gebran, A.; He, Y.; Joo, W.; Kokoroskos, N.; Velmahos, G.; Olsen, B. D.; Hammond, P. T. Modulating Nanoparticle Size to Understand Factors Affecting Hemostatic Efficacy and Maximize Survival in a Lethal Inferior Vena Cava Injury Model. ACS Nano, 2022, 16(2), 2494–2510. doi: 10.1021/acsnano.1c09108
  85. Tang, W.; Panja, S.; Jogdeo, C. M.; Tang, S.; Ding, L.; Yu, A.; Foster, K. W.; Dsouza, D. L.; Chhonker, Y. S.; Jensen-Smith, H.; Jang, H.-S.; Boesen, E. I.; Murry, D. J.; Padanilam, B.; Oupický, D. Modified Chitosan for Effective Renal Delivery of SiRNA to Treat Acute Kidney Injury. Biomaterials, 2022, 285, 121562. doi: 10.1016/j.biomaterials.2022.121562
  86. Mousa, A. H.; Bliman, D.; Hiram Betancourt, L.; Hellman, K.; Ekström, P.; Savvakis, M.; Strakosas, X.; Marko-Varga, G.; Berggren, M.; Hjort, M.; Ek, F.; Olsson, R. Method Matters: Exploring Alkoxysulfonate-Functionalized Poly(3,4-Ethylenedioxythiophene) and Its Unintentional Self-Aggregating Copolymer toward Injectable Bioelectronics. Chem. Mater., 2022, 34(6), 2752–2763. doi: 10.1021/acs.chemmater.1c04342
  87. Aupič, J.; Lapenta, F.; Strmšek, Ž.; Merljak, E.; Plaper, T.; Jerala, R. Metal Ion–Regulated Assembly of Designed Modular Protein Cages. Science Advances, 2022, 8(24), eabm8243. doi: 10.1126/sciadv.abm8243
  88. Zheng, T.; Zhang, Q.; Peng, Z.; Li, D.; Wu, X.; Liu, Y.; Li, P.; Zhang, J.; Du, G. Metabolite-Based Cell Sorting Workflow for Identifying Microbes Producing Carbonyls in Tobacco Leaves. Appl Microbiol Biotechnol, 2022, 106(11), 4199–4209. doi: 10.1007/s00253-022-11982-3
  89. Hu, L.; Wang, J.; Lin, D.; Shen, Y.; Huang, H.; Cao, Y.; Li, Y.; Li, K.; Yu, Y.; Yu, Y.; Chu, C.; Qin, L.; Wang, X.; Zhang, H.; Fulton, D.; Chen, F. Mesenchymal Stem Cell–Derived Nanovesicles as a Credible Agent for Therapy of Pulmonary Hypertension. Am J Respir Cell Mol Biol, 2022, 67(1), 61–75. doi: 10.1165/rcmb.2021-0415OC
  90. Casey, L. M.; Hughes, K. R.; Saunders, M. N.; Miller, S. D.; Pearson, R. M.; Shea, L. D. Mechanistic Contributions of Kupffer Cells and Liver Sinusoidal Endothelial Cells in Nanoparticle-Induced Antigen-Specific Immune Tolerance. Biomaterials, 2022, 283, 121457. doi: 10.1016/j.biomaterials.2022.121457
  91. Backes, I. M.; Byrd, B. K.; Slein, M. D.; Patel, C. D.; Taylor, S. A.; Garland, C. R.; MacDonald, S. W.; Balazs, A. B.; Davis, S. C.; Ackerman, M. E.; Leib, D. A. Maternally Transferred MAbs Protect Neonatal Mice from HSV-Induced Mortality and Morbidity. Journal of Experimental Medicine, 2022, 219(12), e20220110. doi: 10.1084/jem.20220110
  92. Wang, Z.; Chen, D.; Guan, D.; Liang, X.; Xue, J.; Zhao, H.; Song, G.; Lou, J.; He, Y.; Zhang, H. Material Properties of Phase-Separated TFEB Condensates Regulate the Autophagy-Lysosome Pathway. Journal of Cell Biology, 2022, 221(5), e202112024. doi: 10.1083/jcb.202112024
  93. Caronna, F.; Glimpel, N.; Paar, G.-P.; Gries, T.; Blaeser, A.; Do, K.; B. Dolan, E.; Ronan, W. Manufacturing, Characterization, and Degradation of a Poly(Lactic Acid) Warp-Knitted Spacer Fabric Scaffold as a Candidate for Tissue Engineering Applications. Biomaterials Science, 2022, 10(14), 3793–3807. doi: 10.1039/D1BM02027G
  94. Grzelak, J.; Gázquez, J.; Grayston, A.; Teles, M.; Herranz, F.; Roher, N.; Rosell, A.; Roig, A.; Gich, M. Magnetic Mesoporous Silica Nanorods Loaded with Ceria and Functionalized with Fluorophores for Multimodal Imaging. ACS Appl. Nano Mater., 2022, 5(2), 2113–2125. doi: 10.1021/acsanm.1c03837
  95. Wang, Y.; Zhang, Y.; Guan, Y.; Zhang, Y. Magnetic Field-Assisted Fast Assembly of Microgel Colloidal Crystals. Langmuir, 2022, 38(19), 6057–6065. doi: 10.1021/acs.langmuir.2c00297
  96. Bose, M.; Lampe, M.; Mahamid, J.; Ephrussi, A. Liquid-to-Solid Phase Transition of Oskar Ribonucleoprotein Granules Is Essential for Their Function in Drosophila Embryonic Development. Cell, 2022, 185(8), 1308-1324.e23. doi: 10.1016/j.cell.2022.02.022
  97. Ambrozkiewicz, M. C.; Borisova, E.; Newman, A. G.; Kraushar, M. L.; Schaub, T.; Dannenberg, R.; Brockmann, M.; Rosário, M.; Turko, P.; Jahn, O.; Kaplan, D. R.; Iwawaki, T.; Spahn, C. M. T.; Rosenmund, C.; Tarabykin, V. Ire1α-Regulated MRNA Translation Rate Controls the Identity and Polarity of Upper Layer Cortical Neurons. bioRxiv, 2022, preprint. doi: 10.1101/2021.06.23.449563
  98. Zhao, Y.; Liu, T.; Ardana, A.; Fletcher, N. L.; Houston, Z. H.; Blakey, I.; Thurecht, K. J. Investigation of a Dual SiRNA/Chemotherapy Delivery System for Breast Cancer Therapy. ACS Omega, 2022, 7(20), 17119–17127. doi: 10.1021/acsomega.2c00620
  99. Warmt, C.; Yaslanmaz, C.; Henkel, J. Investigation and Validation of Labelling Loop Mediated Isothermal Amplification (LAMP) Products with Different Nucleotide Modifications for Various Downstream Analysis. Sci Rep, 2022, 12(1), 7137. doi: 10.1038/s41598-022-11320-7
  100. Macdougall, L. J.; Hoffman, T. E.; Kirkpatrick, B. E.; Fairbanks, B. D.; Bowman, C. N.; Spencer, S. L.; Anseth, K. S. Intracellular Crowding by Bio-Orthogonal Hydrogel Formation Induces Reversible Molecular Stasis. Advanced Materials, 2022, 34(31), 2202882. doi: 10.1002/adma.202202882
  101. Liu, J.; Lu, F.; Chen, Y.; Plow, E.; Qin, J. Integrin Mediates Cell Entry of the SARS-CoV-2 Virus Independent of Cellular Receptor ACE2. Journal of Biological Chemistry, 2022, 298(3), 101710. doi: 10.1016/j.jbc.2022.101710
  102. Nkanga, C. I.; Ortega-Rivera, O. A.; Shin, M. D.; Moreno-Gonzalez, M. A.; Steinmetz, N. F. Injectable Slow-Release Hydrogel Formulation of a Plant Virus-Based COVID-19 Vaccine Candidate. Biomacromolecules, 2022, 23(4), 1812–1825. doi: 10.1021/acs.biomac.2c00112
  103. Grodetskaya, T. A.; Evlakov, P. M.; Fedorova, O. A.; Mikhin, V. I.; Zakharova, O. V.; Kolesnikov, E. A.; Evtushenko, N. A.; Gusev, A. A. Influence of Copper Oxide Nanoparticles on Gene Expression of Birch Clones In Vitro under Stress Caused by Phytopathogens. Nanomaterials, 2022, 12(5), 864. doi: 10.3390/nano12050864
  104. Radler, P.; Baranova, N.; Caldas, P.; Sommer, C.; López-Pelegrín, M.; Michalik, D.; Loose, M. In Vitro Reconstitution of Escherichia Coli Divisome Activation. Nat Commun, 2022, 13(1), 2635. doi: 10.1038/s41467-022-30301-y
  105. Kikuma, T.; Ibuki, H.; Nakamoto, M.; Seko, A.; Ito, Y.; Takeda, Y. In Vitro Mannosidase Activity of EDEM3 against Asparagine-Linked Oligomannose-Type Glycans. Biochemical and Biophysical Research Communications, 2022, 612, 44–49. doi: 10.1016/j.bbrc.2022.04.094
  106. Fujii, S.; Takano, S.; Nakazawa, K.; Sakurai, K. Impact of Zwitterionic Polymers on the Tumor Permeability of Molecular Bottlebrush-Based Nanoparticles. Biomacromolecules, 2022, 23(7), 2846–2855. doi: 10.1021/acs.biomac.2c00216
  107. Barmin, R. A.; Rudakovskaya, P. G.; Chernyshev, V. S.; Guslyakova, O. I.; Sindeeva, O. A.; Prikhozhdenko, E. S.; Bratashov, D. N.; Abdurashitov, A. S.; Maksimova, E. A.; Demina, P. A.; Khaydukov, E. V.; Gayer, A. V.; Shirshin, E. A.; Solovev, A. A.; Mei, Y.; Gorin, D. A. Impact of Fluorescent Dyes on the Physicochemical Parameters of Microbubbles Stabilized by Albumin-Dye Complex. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2022, 647, 129095. doi: 10.1016/j.colsurfa.2022.129095
  108. Chen, S.; Li, W.; Zheng, X.; Yu, P.; Wang, P.; Sun, Z.; Xu, Y.; Jiao, D.; Ye, X.; Cai, M.; Shen, M.; Wang, M.; Zhang, Q.; Kong, F.; Wang, Y.; He, J.; Wei, H.; Shi, F.; Du, J. Immunomagnetic Microscopy of Tumor Tissues Using Quantum Sensors in Diamond. Proc. Natl. Acad. Sci. U.S.A., 2022, 119(5), e2118876119. doi: 10.1073/pnas.2118876119
  109. Tian, T.; Liang, R.; Erel-Akbaba, G.; Saad, L.; Obeid, P. J.; Gao, J.; Chiocca, E. A.; Weissleder, R.; Tannous, B. A. Immune Checkpoint Inhibition in GBM Primed with Radiation by Engineered Extracellular Vesicles. ACS Nano, 2022, 16(2), 1940–1953. doi: 10.1021/acsnano.1c05505
  110. Lu, M.; Huang, X.; Cai, X.; Sun, J.; Liu, X.; Weng, L.; Zhu, L.; Luo, Q.; Chen, Z. Hypoxia-Responsive Stereocomplex Polymeric Micelles with Improved Drug Loading Inhibit Breast Cancer Metastasis in an Orthotopic Murine Model. ACS Appl. Mater. Interfaces, 2022, 14(18), 20551–20565. doi: 10.1021/acsami.1c23737
  111. Chelomin, V. P.; Mazur, A. A.; Slobodskova, V. V.; Kukla, S. P.; Dovzhenko, N. V. Genotoxic Properties of Polystyrene (PS) Microspheres in the Filter-Feeder Mollusk Mytilus Trossulus (Gould, 1850). Journal of Marine Science and Engineering, 2022, 10(2), 273. doi: 10.3390/jmse10020273
  112. Zhao, Y.; Miranda Herrera, P. A.; Chang, D.; Hamelin, R.; Long, M. J. C.; Aye, Y. Function-Guided Proximity Mapping Unveils Electrophilic-Metabolite Sensing by Proteins Not Present in Their Canonical Locales. Proc. Natl. Acad. Sci. U.S.A., 2022, 119(5), e2120687119. doi: 10.1073/pnas.2120687119
  113. Jena, S.; Parker, L. L. Fluorescence Lifetime Imaging Probes for Cell-Based Measurements of Enzyme Activity. Biomedical Engineering Technologies: Methods in Molecular Biology, 2022, 2394, 133–162. doi: 10.1007/978-1-0716-1811-0_9
  114. Valles, M.; Pujals, S.; Albertazzi, L.; Sánchez, S. Enzyme Purification Improves the Enzyme Loading, Self-Propulsion, and Endurance Performance of Micromotors. ACS Nano, 2022, 16(4), 5615–5626. doi: 10.1021/acsnano.1c10520
  115. McGorman, B.; Fantoni, N. Z.; O’Carroll, S.; Ziemele, A.; El-Sagheer, A. H.; Brown, T.; Kellett, A. Enzymatic Synthesis of Chemical Nuclease Triplex-Forming Oligonucleotides with Gene-Silencing Applications. Nucleic Acids Research, 2022, 50(10), 5467–5481. doi: 10.1093/nar/gkac438
  116. Jiang, H.; Chiang, C. Y.; Chen, Z.; Nathan, S.; D’Agostino, G.; Paulo, J. A.; Song, G.; Zhu, H.; Gabelli, S. B.; Cole, P. A. Enzymatic Analysis of WWP2 E3 Ubiquitin Ligase Using Protein Microarrays Identifies Autophagy-Related Substrates. Journal of Biological Chemistry, 2022, 298(5), 101854. doi: 10.1016/j.jbc.2022.101854
  117. Katila, N.; Duwa, R.; Bhurtel, S.; Khanal, S.; Maharjan, S.; Jeong, J.-H.; Lee, S.; Choi, D.-Y.; Yook, S. Enhancement of Blood–Brain Barrier Penetration and the Neuroprotective Effect of Resveratrol. Journal of Controlled Release, 2022, 346, 1–19. doi: 10.1016/j.jconrel.2022.04.003
  118. Chang, Y.; Syahirah, R.; Wang, X.; Jin, G.; Torregrosa-Allen, S.; Elzey, B. D.; Hummel, S. N.; Wang, T.; Li, C.; Lian, X.; Deng, Q.; Broxmeyer, H. E.; Bao, X. Engineering Chimeric Antigen Receptor Neutrophils from Human Pluripotent Stem Cells for Targeted Cancer Immunotherapy. Cell Reports, 2022, 40(3), 111128. doi: 10.1016/j.celrep.2022.111128
  119. Suresh, D.; Suresh, A.; Kannan, R. Engineering Biomolecular Systems: Controlling the Self-Assembly of Gelatin to Form Ultra-Small Bioactive Nanomaterials. Bioactive Materials, 2022, 8, 321–336. doi: 10.1016/j.bioactmat.2022.02.035
  120. Babi, M.; Fatona, A.; Li, X.; Cerson, C.; Jarvis, V. M.; Abitbol, T.; Moran-Mirabal, J. M. Efficient Labeling of Nanocellulose for High-Resolution Fluorescence Microscopy Applications. Biomacromolecules, 2022, 23(5), 1981–1994. doi: 10.1021/acs.biomac.1c01698
  121. Novoselova, M.; Chernyshev, V. S.; Schulga, A.; Konovalova, E. V.; Chuprov-Netochin, R. N.; Abakumova, T. O.; German, S.; Shipunova, V. O.; Mokrousov, M. D.; Prikhozhdenko, E.; Bratashov, D. N.; Nozdriukhin, D. V.; Bogorodskiy, A.; Grishin, O.; Kosolobov, S. S.; Khlebtsov, B. N.; Inozemtseva, O.; Zatsepin, T. S.; Deyev, S. M.; Gorin, D. A. Effect of Surface Modification of Multifunctional Nanocomposite Drug Delivery Carriers with DARPin on Their Biodistribution In Vitro and In Vivo. ACS Appl. Bio Mater., 2022, 5(6), 2976–2989. doi: 10.1021/acsabm.2c00289
  122. Ray, S.; Wirth, D. M.; Ortega-Rivera, O. A.; Steinmetz, N. F.; Pokorski, J. K. Dissolving Microneedle Delivery of a Prophylactic HPV Vaccine. Biomacromolecules, 2022, 23(3), 903–912. doi: 10.1021/acs.biomac.1c01345
  123. Olson, S. W.; Turner, A.-M. W.; Arney, J. W.; Saleem, I.; Weidmann, C. A.; Margolis, D. M.; Weeks, K. M.; Mustoe, A. M. Discovery of a Large-Scale, Cell-State-Responsive Allosteric Switch in the 7SK RNA Using DANCE-MaP. Molecular Cell, 2022, 82(9), 1708-1723.e10. doi: 10.1016/j.molcel.2022.02.009
  124. Babi, M.; Palermo, A.; Abitbol, T.; Fatona, A.; Jarvis, V.; Nayak, A.; Cranston, E.; Moran-Mirabal, J. Direct Imaging of the Alternating Disordered and Crystalline Structure of Cellulose Fibrils via Super-Resolution Fluorescence Microscopy. ChemRxiv, 2022, preprint. doi: 10.26434/chemrxiv-2022-0jqng
  125. Chen, Y.; Wang, Y.; Jiang, X.; Cai, J.; Chen, Y.; Huang, H.; Yang, Y.; Zheng, L.; Zhao, J.; Gao, M. Dimethylamino Group Modified Polydopamine Nanoparticles with Positive Charges to Scavenge Cell-Free DNA for Rheumatoid Arthritis Therapy. Bioactive Materials, 2022, 18, 409–420. doi: 10.1016/j.bioactmat.2022.03.028
  126. Bieber, J. M.; Sanman, L. E.; Sun, X.; Hammerlindl, H.; Bao, F.; Roth, M. A.; Koleske, M. L.; Huang, L.; Aweeka, F.; Wu, L. F.; Altschuler, S. J. Differential Toxicity to Murine Small and Large Intestinal Epithelium Induced by Oncology Drugs. Commun Biol, 2022, 5(1), 1–11. doi: 10.1038/s42003-022-03048-x
  127. Bessonova, T. A.; Fando, M. S.; Kostareva, O. S.; Tutukina, M. N.; Ozoline, O. N.; Gelfand, M. S.; Nikulin, A. D.; Tishchenko, S. V. Differential Impact of Hexuronate Regulators ExuR and UxuR on the Escherichia Coli Proteome. International Journal of Molecular Sciences, 2022, 23(15), 8379. doi: 10.3390/ijms23158379
  128. Matoori, S.; Mooney, D. J. Development of a Liposomal Near-Infrared Fluorescence Lactate Assay for Human Blood. Biomaterials, 2022, 283, 121475. doi: 10.1016/j.biomaterials.2022.121475
  129. Marasini, N.; Er, G.; Fu, C.; Subasic, C. N.; Ibrahim, J.; Skwarczynski, M.; Toth, I.; Whittaker, A. K.; Kaminskas, L. M. Development of a Hyperbranched Polymer-Based Methotrexate Nanomedicine for Rheumatoid Arthritis. Acta Biomaterialia, 2022, 142, 298–307. doi: 10.1016/j.actbio.2022.01.054.
  130. Ryabchevskaya, E. M.; Granovskiy, D. L.; Evtushenko, E. A.; Ivanov, P. A.; Kondakova, O. A.; Nikitin, N. A.; Karpova, O. V. Designing Stable Bacillus Anthracis Antigens with a View to Recombinant Anthrax Vaccine Development. Pharmaceutics, 2022, 14(4), 806. doi: 10.3390/pharmaceutics14040806
  131. Demina, P. A.; Saveleva, M. S.; Anisimov, R. A.; Prikhozhdenko, E. S.; Voronin, D. V.; Abalymov, A. A.; Cherednichenko, K. A.; Timaeva, O. I.; Lomova, M. V. Degradation of Hybrid Drug Delivery Carriers with a Mineral Core and a Protein–Tannin Shell under Proteolytic Hydrolases. Biomimetics, 2022, 7(2), 61. doi: 10.3390/biomimetics7020061
  132. Tsavkelova, E. A.; Glukhareva, I. D.; Volynchikova, E. A.; Egorova, M. A.; Leontieva, M. R.; Malakhova, D. V.; Kolomeitseva, G. L.; Netrusov, A. I. Cyanobacterial Root Associations of Leafless Epiphytic Orchids. Microorganisms, 2022, 10(5), 1006. doi: 10.3390/microorganisms10051006
  133. Garafutdinov, R. R.; Chemeris, D. A.; Sakhabutdinova, A. R.; Moiseev, K. V.; Urmancheev, S. F.; Mikhaylenko, C. I.; Privalov, L. Y.; Chemeris, A. V. Convective Polymerase Chain Reaction in Standard Microtubes. Analytical Biochemistry, 2022, 641, 114565. doi: 10.1016/j.ab.2022.114565
  134. Zivotska, H.; Mokry, M.; Rodrigo, M. A. M.; Michalkova, H.; Kapolkova, K.; Splichal, Z.; Stokowa-Soltys, K.; Milosavljevic, V.; Guran, R.; Richtera, L.; Haddad, Y.; Rex, S.; Heger, Z. Conotoxin-Derived Biomimetic Coiled Cone-Shaped Peptide as Ligand for Selective Nanodelivery to Norepinephrine Transporter-Expressing Neuroblastoma Cells. Applied Materials Today, 2022, 27, 101410. doi: 10.1016/j.apmt.2022.101410
  135. Konhäuser, M.; Kannaujiya, V. K.; Steiert, E.; Schwickert, K.; Schirmeister, T.; Wich, P. R. Co-Encapsulation of l-Asparaginase and Etoposide in Dextran Nanoparticles for Synergistic Effect in Chronic Myeloid Leukemia Cells. International Journal of Pharmaceutics, 2022, 622, 121796. doi: 10.1016/j.ijpharm.2022.121796
  136. Hanisch, D.; Krumm, A.; Diehl, T.; Stork, C. M.; Dejung, M.; Butter, F.; Kim, E.; Brenner, W.; Fritz, G.; Hofmann, T. G.; Roos, W. P. Class I HDAC Overexpression Promotes Temozolomide Resistance in Glioma Cells by Regulating RAD18 Expression. Cell Death Dis, 2022, 13(4), 1–12. doi: 10.1038/s41419-022-04751-7
  137. Kolyvanova, M. A.; Klimovich, M. A.; Shibaeva, A. V.; Koshevaya, E. D.; Bushmanov, Y. A.; Belousov, A. V.; Kuzmin, V. A.; Morozov, V. N. Cholesteric Liquid-Crystalline DNA – a New Type of Chemical Detector of Ionizing Radiation. Liquid Crystals, 2022, 49(10), 1359–1366. doi: 10.1080/02678292.2022.2032854
  138. Lin, G.; Huang, J.; Zhang, M.; Chen, S.; Zhang, M. Chitosan-Crosslinked Low Molecular Weight PEI-Conjugated Iron Oxide Nanoparticle for Safe and Effective DNA Delivery to Breast Cancer Cells. Nanomaterials, 2022, 12(4), 584. doi: 10.3390/nano12040584
  139. Perzanowska, O.; Smietanski, M.; Jemielity, J.; Kowalska, J. Chemically Modified Poly(A) Analogs Targeting PABP: Structure Activity Relationship and Translation Inhibitory Properties. Chemistry – A European Journal, 2022, 28(42), e202201115. doi: 10.1002/chem.202201115
  140. Piranej, S.; Bazrafshan, A.; Salaita, K. Chemical-to-Mechanical Molecular Computation Using DNA-Based Motors with Onboard Logic. Nat. Nanotechnol., 2022, 17(5), 514–523. doi: 10.1038/s41565-022-01080-w
  141. Ahunbay, E.; Steffen, F. D.; Zelger-Paulus, S.; Sigel, R. K. O. Chemical Dual End-Labeling of Large Ribozymes. DNAzymes: Methods and Protocols, 2022, 2439, 191–204. doi: 10.1007/978-1-0716-2047-2_13
  142. Fouquet, J. P.; Sikpa, D.; Lebel, R.; Sibgatulin, R.; Krämer, M.; Herrmann, K.-H.; Deistung, A.; Tremblay, L.; Reichenbach, J. R.; Lepage, M. Characterization of Microparticles of Iron Oxide for Magnetic Resonance Imaging. Magnetic Resonance Imaging, 2022, 92, 67–81. doi: 10.1016/j.mri.2022.05.020
  143. Ramm, F.; Jack, L.; Kaser, D.; Schloßhauer, J. L.; Zemella, A.; Kubick, S. Cell-Free Systems Enable the Production of AB5 Toxins for Diagnostic Applications. Toxins, 2022, 14(4), 233. doi: 10.3390/toxins14040233
  144. Ksenofontov, A. A.; Lukanov, M. M.; Bocharov, P. S. Can Machine Learning Methods Accurately Predict the Molar Absorption Coefficient of Different Classes of Dyes?. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 279, 121442. doi: 10.1016/j.saa.2022.121442
  145. Zeng, L.; Liu, Y.; Nguyenla, X. H.; Abbott, T. R.; Han, M.; Zhu, Y.; Chemparathy, A.; Lin, X.; Chen, X.; Wang, H.; Rane, D. A.; Spatz, J. M.; Jain, S.; Rustagi, A.; Pinsky, B.; Zepeda, A. E.; Kadina, A. P.; Walker, J. A.; Holden, K.; Temperton, N.; Cochran, J. R.; Barron, A. E.; Connolly, M. D.; Blish, C. A.; Lewis, D. B.; Stanley, S. A.; La Russa, M. F.; Qi, L. S. Broad-Spectrum CRISPR-Mediated Inhibition of SARS-CoV-2 Variants and Endemic Coronaviruses in Vitro. Nat Commun, 2022, 13(1), 2766. doi: 10.1038/s41467-022-30546-7
  146. Yu, H.; Palazzolo, J. S.; Zhou, J.; Hu, Y.; Niego, B.; Pan, S.; Ju, Y.; Wang, T.-Y.; Lin, Z.; Hagemeyer, C. E.; Caruso, F. Bioresponsive Polyphenol-Based Nanoparticles as Thrombolytic Drug Carriers. ACS Appl. Mater. Interfaces, 2022, 14(3), 3740–3751. doi: 10.1021/acsami.1c19820
  147. Hayun, H.; Arkadash, V.; Sananes, A.; Arbely, E.; Stepensky, D.; Papo, N. Bioorthogonal PEGylation Prolongs the Elimination Half-Life of N-TIMP2 While Retaining MMP Inhibition. Bioconjugate Chem., 2022, 33(5), 795–806. doi: 10.1021/acs.bioconjchem.2c00059
  148. Li, S.; Co, C. M.; Izuagbe, S.; Hong, Y.; Liao, J.; Borrelli Jr., J.; Tang, L. Biomolecules-Releasing Click Chemistry-Based Bioadhesives for Repairing Acetabular Labrum Tears. Journal of Orthopaedic Research, 2022, 40(11), 2646–2655. doi: 10.1002/jor.25290
  149. Tengjisi; Liu, Y.; Zou, D.; Yang, G.; Zhao, C.-X. Bioinspired Core-Shell Silica Nanoparticles Monitoring Extra- and Intra-Cellular Drug Release. Journal of Colloid and Interface Science, 2022, 624, 242–250. doi: 10.1016/j.jcis.2022.05.099
  150. de Paiva, I. M.; Vakili, M. R.; Soleimani, A. H.; Tabatabaei Dakhili, S. A.; Munira, S.; Paladino, M.; Martin, G.; Jirik, F. R.; Hall, D. G.; Weinfeld, M.; Lavasanifar, A. Biodistribution and Activity of EGFR Targeted Polymeric Micelles Delivering a New Inhibitor of DNA Repair to Orthotopic Colorectal Cancer Xenografts with Metastasis. Mol. Pharmaceutics, 2022, 19(6), 1825–1838. doi: 10.1021/acs.molpharmaceut.1c00918
  151. de Jesus, V.; Schmid, J.; Fürtig, B. Binding of 30S Ribosome Induces Single-Stranded Conformation Within and Downstream of the Expression Platform in a Translational Riboswitch. Journal of Molecular Biology, 2022, 434(18), 167668. doi: 10.1016/j.jmb.2022.167668
  152. Białas, N.; Sokolova, V.; van der Meer, S. B.; Knuschke, T.; Ruks, T.; Klein, K.; Westendorf, A. M.; Epple, M. Bacteria (E. Coli) Take up Ultrasmall Gold Nanoparticles (2 Nm) as Shown by Different Optical Microscopic Techniques (CLSM, SIM, STORM). Nano Select, 2022, 3(10), 1407–1420. doi: 10.1002/nano.202200049
  153. Lella, M.; Oh, M. W.; Kuo, S. H.; Lau, G. W.; Tal-Gan, Y. Attenuating the Streptococcus Pneumoniae Competence Regulon Using Urea-Bridged Cyclic Dominant-Negative Competence-Stimulating Peptide Analogs. J. Med. Chem., 2022, 65(9), 6826–6839. doi: 10.1021/acs.jmedchem.2c00148
  154. Gaikwad, H.; Li, Y.; Wang, G.; Li, R.; Dai, S.; Rester, C.; Kedl, R.; Saba, L.; Banda, N. K.; Scheinman, R. I.; Patrick, C.; Mallela, K. M. G.; Moghimi, S. M.; Simberg, D. Antibody-Dependent Complement Responses toward SARS-CoV-2 Receptor-Binding Domain Immobilized on “Pseudovirus-like” Nanoparticles. ACS Nano, 2022, 16(6), 8704–8715. doi: 10.1021/acsnano.2c02794
  155. Zheng, J.; Hu, R.; Yang, Y.; Wang, Y.; Wang, Q.; Xu, S.; Yao, P.; Liu, Z.; Zhou, J.; Yang, J.; Bao, Y.; Zhang, D.; Shen, W.; Zhou, Z. Antibiotic-Loaded Reactive Oxygen Species-Responsive Nanomedicine for Effective Management of Chronic Bacterial Prostatitis. Acta Biomaterialia, 2022, 143, 471–486. doi: 10.1016/j.actbio.2022.02.044
  156. Wu, D.; Wang, Z.; Huang, J.; Huang, L.; Zhang, S.; Zhao, R.; Li, W.; Chen, D.; Ou, G. An Antagonistic Pleiotropic Gene Regulates the Reproduction and Longevity Tradeoff. Proceedings of the National Academy of Sciences, 2022, 119(18), e2120311119. doi: 10.1073/pnas.2120311119
  157. Osipova, O.; Zakharova, N.; Pyankov, I.; Egorova, A.; Kislova, A.; Lavrentieva, A.; Kiselev, A.; Tennikova, T.; Korzhikova-Vlakh, E. Amphiphilic PH-Sensitive Polypeptides for SiRNA Delivery. Journal of Drug Delivery Science and Technology, 2022, 69, 103135. doi: 10.1016/j.jddst.2022.103135
  158. Mitrach, F.; Schmid, M.; Toussaint, M.; Dukic-Stefanovic, S.; Deuther-Conrad, W.; Franke, H.; Ewe, A.; Aigner, A.; Wölk, C.; Brust, P.; Hacker, M. C.; Schulz-Siegmund, M. Amphiphilic Anionic Oligomer-Stabilized Calcium Phosphate Nanoparticles with Prospects in SiRNA Delivery via Convection-Enhanced Delivery. Pharmaceutics, 2022, 14(2), 326. doi: 10.3390/pharmaceutics14020326
  159. Hong, S.-N.; Kim, M.; Park, J.-A.; Kang, M.; Cha, H.; Park, S.; Kim, J. K.; Pac, J.; Seo, Y.; Kim, S.; Kim, M.; Kim, D. W.; Lee, Y. Alleviation of Surgery-Induced Osteitis in Sinonasal Cavity by Dexamethasone-Loaded Poly(Lactic-Co-Glycolic Acid) (PLGA) Microparticles with Strong Calcium-Binding Affinity. Pharmaceutics, 2022, 14(3), 546. doi: 10.3390/pharmaceutics14030546
  160. Dinesen, A.; Winther, A.; Wall, A.; Märcher, A.; Palmfeldt, J.; Chudasama, V.; Wengel, J.; Gothelf, K. V.; Baker, J. R.; Howard, K. A. Albumin Biomolecular Drug Designs Stabilized through Improved Thiol Conjugation and a Modular Locked Nucleic Acid Functionalized Assembly. Bioconjugate Chem., 2022, 33(2), 333–342. doi: 10.1021/acs.bioconjchem.1c00561
  161. Edr, A.; Wrobel, D.; Krupková, A.; Šťastná, L. Č.; Cuřínová, P.; Novák, A.; Malý, J.; Kalasová, J.; Malý, J.; Malý, M.; Strašák, T. Adaptive Synthesis of Functional Amphiphilic Dendrons as a Novel Approach to Artificial Supramolecular Objects. International Journal of Molecular Sciences, 2022, 23(4), 2114. doi: 10.3390/ijms23042114
  162. Lee, J. Y.; Wing, P. A.; Gala, D. S.; Noerenberg, M.; Järvelin, A. I.; Titlow, J.; Zhuang, X.; Palmalux, N.; Iselin, L.; Thompson, M. K.; Parton, R. M.; Prange-Barczynska, M.; Wainman, A.; Salguero, F. J.; Bishop, T.; Agranoff, D.; James, W.; Castello, A.; McKeating, J. A.; Davis, I. Absolute Quantitation of Individual SARS-CoV-2 RNA Molecules Provides a New Paradigm for Infection Dynamics and Variant Differences. eLife, 2022, 11, e74153. doi: 10.7554/eLife.74153
  163. Cheng, B.; Ahn, H.-H.; Nam, H.; Jiang, Z.; Gao, F. J.; Minn, I.; Pomper, M. G. A Unique Core–Shell Structured, Glycol Chitosan-Based Nanoparticle Achieves Cancer-Selective Gene Delivery with Reduced Off-Target Effects. Pharmaceutics, 2022, 14(2), 373. doi: 10.3390/pharmaceutics14020373
  164. Dai, Z.; Wang, Q.; Tang, J.; Qu, R.; Wu, M.; Li, H.; Yang, Y.; Zhen, X.; Yu, C. A Sub-6 Nm MnFe2O4-Dichloroacetic Acid Nanocomposite Modulates Tumor Metabolism and Catabolism for Reversing Tumor Immunosuppressive Microenvironment and Boosting Immunotherapy. Biomaterials, 2022, 284, 121533. doi: 10.1016/j.biomaterials.2022.121533
  165. Lin, C.-H.; Sun, Y. J.; Lee, S. H.; Mujica, E. M.; Kunchur, C. R.; Wu, M.-R.; Yang, J.; Jung, Y. S.; Chiang, B.; Wang, S.; Mahajan, V. B. A Protocol to Inject Ocular Drug Implants into Mouse Eyes. STAR Protocols, 2022, 3(1), 101143. doi: 10.1016/j.xpro.2022.101143
  166. Kim, R.; Wang, Y.; Sims, C. E.; Allbritton, N. L. A Platform for Co-Culture of Primary Human Colonic Epithelium With Anaerobic Probiotic Bacteria. Front Bioeng Biotechnol, 2022, 10, 890396. doi: 10.3389/fbioe.2022.890396
  167. Fujii, S.; Sakurai, K. Zwitterionic Amino Acid Polymer-Grafted Core-Crosslinked Particle toward Tumor Delivery. Biomacromolecules, 2022, 23(9), 3968–3977. doi: 10.1021/acs.biomac.2c00803
  168. Xu, J.; Zhang, Y.; Liu, Y.; You, Y.; Li, F.; Chen, Y.; Xie, L.; Tong, S.; Zhou, S.; Liang, K.; Huang, Y.; Jiang, G.; Song, Q.; Mei, N.; Ma, F.; Gao, X.; Wang, H.; Chen, J. Vitality-Enhanced Dual-Modal Tracking System Reveals the Dynamic Fate of Mesenchymal Stem Cells for Stroke Therapy. Small, 2022, 18(47), 2203431. doi: 10.1002/smll.202203431
  169. Mitmoen, M.; Kedem, O. UV- and Visible-Light Photopatterning of Molecular Gradients Using the Thiol–Yne Click Reaction. ACS Appl. Mater. Interfaces, 2022, 14(28), 32696–32705. doi: 10.1021/acsami.2c06946.
  170. Lee, W. Y.; Chapman, D. V.; Yu, F.; Tait, W. R. T.; Thedford, R. P.; Freychet, G.; Zhernenkov, M.; Estroff, L. A.; Wiesner, U. B. Triblock Terpolymer Thin Film Nanocomposites Enabling Two-Color Optical Super-Resolution Microscopy. Macromolecules, 2022, 55(21), 9452–9464. doi: 10.1021/acs.macromol.2c01017
  171. Lee, W. Y.; Chapman, D. V.; Yu, F.; Tait, W. R. T.; Thedford, R. P.; Freychet, G.; Zhernenkov, M.; Estroff, L. A.; Wiesner, U. B. Triblock Terpolymer Thin Film Nanocomposites Enabling Two-Color Optical Super-Resolution Microscopy. Macromolecules, 2022, 55(21), 9452–9464. doi: 10.1021/acs.macromol.2c01017
  172. Liao, F.-H.; Yao, C.-N.; Chen, S.-P.; Wu, T.-H.; Lin, S.-Y. Transdermal Delivery of Succinate Accelerates Energy Dissipation of Brown Adipocytes to Reduce Remote Fat Accumulation. Mol. Pharmaceutics, 2022, 19(11), 4299–4310. doi: 10.1021/acs.molpharmaceut.2c00628
  173. Wang, Z.; He, Y.; Tan, Z. Transcription Analysis of Liver and Muscle Tissues from Landrace Finishing Pigs with Different Feed Conversion Ratios. Genes, 2022, 13(11), 2067. doi: 10.3390/genes13112067
  174. Ghaffari Sharaf, M.; Waduthanthri, K. D.; Crichton, A.; Damji, K. F.; Unsworth, L. D. Towards Preventing Exfoliation Glaucoma by Targeting and Removing Fibrillar Aggregates Associated with Exfoliation Syndrome. Journal of Nanobiotechnology, 2022, 20(1), 459. doi: 10.1186/s12951-022-01665-6
  175. Mai, Y.; Ouyang, Y.; Yu, M.; Qin, Y.; Girardi, M.; Saltzman, W. M.; Cocco, E.; Zhao, C.; Yu, L.; Jia, Y.; Xiao, L.; Dou, L.; Deng, W.; Liu, Y.; Xie, J.; Deng, Y. Topical Formulation Based on Disease-Specific Nanoparticles for Single-Dose Cure of Psoriasis. Journal of Controlled Release, 2022, 349, 354–366. doi: 10.1016/j.jconrel.2022.07.006
  176. Alexandrova, V. V.; Anisimov, M. N.; Zaitsev, A. V.; Mustyatsa, V. V.; Popov, V. V.; Ataullakhanov, F. I.; Gudimchuk, N. B. Theory of Tip Structure–Dependent Microtubule Catastrophes and Damage-Induced Microtubule Rescues. Proceedings of the National Academy of Sciences, 2022, 119(46), e2208294119. doi: 10.1073/pnas.2208294119
  177. Senchurova, S. I.; Syryamina, V. N.; Kuznetsova, A. A.; Novopashina, D. S.; Ishchenko, A. A.; Saparbaev, M.; Dzuba, S. A.; Fedorova, O. S.; Kuznetsov, N. A. The Mechanism of Damage Recognition by Apurinic/Apyrimidinic Endonuclease Nfo from Escherichia Coli. Biochimica et Biophysica Acta (BBA) - General Subjects, 2022, 1866(11), 130216. doi: 10.1016/j.bbagen.2022.130216
  178. Cuccaro, A.; De Marchi, L.; Oliva, M.; Monni, G.; Miragliotta, V.; Fumagalli, G.; Freitas, R.; Pretti, C. The Influence of Salinity on the Toxicity of Chemical UV-Filters to Sperms of the Free-Spawning Mussel Mytilus Galloprovincialis (Lamark, 1819). Aquatic Toxicology, 2022, 250, 106263. doi: 10.1016/j.aquatox.2022.106263
  179. Kuiper, E. F. E.; Gallardo, P.; Bergsma, T.; Mari, M.; Kolbe Musskopf, M.; Kuipers, J.; Giepmans, B. N. G.; Steen, A.; Kampinga, H. H.; Veenhoff, L. M.; Bergink, S. The Chaperone DNAJB6 Surveils FG-Nucleoporins and Is Required for Interphase Nuclear Pore Complex Biogenesis. Nat Cell Biol, 2022, 24(11), 1584–1594. doi: 10.1038/s41556-022-01010-x
  180. Duwa, R.; Pokhrel, R. H.; Banstola, A.; Pandit, M.; Shrestha, P.; Jeong, J.-H.; Chang, J.-H.; Yook, S. T-Cell Engaging Poly(Lactic-Co-Glycolic Acid) Nanoparticles as a Modular Platform to Induce a Potent Cytotoxic Immunogenic Response against PD-L1 Overexpressing Cancer. Biomaterials, 2022, 291, 121911. doi: 10.1016/j.biomaterials.2022.121911
  181. Liu, L.; Pan, D.; Chen, S.; Martikainen, M.-V.; Kårlund, A.; Ke, J.; Pulkkinen, H.; Ruhanen, H.; Roponen, M.; Käkelä, R.; Xu, W.; Wang, J.; Lehto, V.-P. Systematic Design of Cell Membrane Coating to Improve Tumor Targeting of Nanoparticles. Nat Commun, 2022, 13(1), 6181. doi: 10.1038/s41467-022-33889-3
  182. Terekhova, N. V.; Lyubina, A. P.; Voloshina, A. D.; Sapunova, A. S.; Khayarov, K. R.; Islamov, D. R.; Usachev, K. S.; Evtugyn, V. G.; Tatarinov, D. A.; Mironov, V. F. Synthesis, Biological Evaluation and Structure-Activity Relationship of 2-(2-Hydroxyaryl)Alkenylphosphonium Salts with Potency as Anti-MRSA Agents. Bioorganic Chemistry, 2022, 127, 106030. doi: 10.1016/j.bioorg.2022.106030
  183. Salazar-Chaparro, A. F.; Halder, S.; Trader, D. J. Synthesis and Application of a Clickable Epoxomicin-Based Probe for Proteasome Activity Analysis. Current Protocols, 2022, 2(7), e490. doi: 10.1002/cpz1.490
  184. Deiss-Yehiely, E.; Brucks, S. D.; Boehnke, N.; Pickering, A. J.; Kiessling, L. L.; Hammond, P. T. Surface Presentation of Hyaluronic Acid Modulates Nanoparticle–Cell Association. Bioconjugate Chem., 2022, 33(11), 2065–2075. doi: 10.1021/acs.bioconjchem.2c00412
  185. Shen, N.; Qi, X.; Bagrov, D. V.; Krechetov, S. P.; Sharapov, M. G.; Durymanov, M. O. Surface Modification of Fibroblasts with Peroxiredoxin-1-Loaded Polymeric Microparticles Increases Cell Mobility, Resistance to Oxidative Stress and Collagen I Production. Colloids and Surfaces B: Biointerfaces, 2022, 219, 112834. doi: 10.1016/j.colsurfb.2022.112834
  186. Judge, R. A.; Sridar, J.; Tunyasuvunakool, K.; Jain, R.; Wang, J. C. K.; Ouch, C.; Xu, J.; Mafi, A.; Nile, A. H.; Remarcik, C.; Smith, C. L.; Ghosh, C.; Xu, C.; Stoll, V.; Jumper, J.; Singh, A. H.; Eaton, D.; Hao, Q. Structure of the PAPP-ABP5 Complex Reveals Mechanism of Substrate Recognition. Nat Commun, 2022, 13(1), 5500. doi: 10.1038/s41467-022-33175-2
  187. Zhou, X.; Sala, G.; Sagis, L. M. C. Structure and Rheological Properties of Oil-Water and Air-Water Interfaces Stabilized with Micellar Casein Isolate and Whey Protein Isolate Mixtures. Food Hydrocolloids, 2022, 133, 107946. doi: 10.1016/j.foodhyd.2022.107946
  188. Kapitonova, A. A.; Tugaeva, K. V.; Varfolomeeva, L. A.; Boyko, K. M.; Cooley, R. B.; Sluchanko, N. N. Structural Basis for the Recognition by 14-3-3 Proteins of a Conditional Binding Site within the Oligomerization Domain of Human Nucleophosmin. Biochemical and Biophysical Research Communications, 2022, 627, 176–183. doi: 10.1016/j.bbrc.2022.08.047
  189. Zavyalova, E.; Tikhonova, D.; Zhdanov, G.; Rudakova, E.; Alferova, V.; Moiseenko, A.; Kamzeeva, P.; Khrulev, A.; Zalevsky, A.; Arutyunyan, A.; Novikov, R.; Kukushkin, V.; Aralov, A. SERS-Based Biosensor with Raman-Active External Responsive Element for Rapid Determination of Adenosine Monophosphate. Analytica Chimica Acta, 2022, 1221, 340140. doi: 10.1016/j.aca.2022.340140
  190. DiSalvo, M.; Patrone, P. N.; Kearsley, A. J.; Cooksey, G. A. Serial Flow Cytometry in an Inertial Focusing Optofluidic Microchip for Direct Assessment of Measurement Variations. Lab Chip, 2022, 22(17), 3217–3228. doi: 10.1039/D1LC01169C
  191. Ge, X.; Hao, Y.; Li, H.; Zhao, H.; Liu, Y.; Liu, Y.; Li, X.; Chen, H.; Zou, J.; Zhang, S.; Huang, L.; Shan, G.; Zhang, Z. Sequential Acid/Reduction Response of Triblock Copolymeric Nanomicelles to Release Camptothecin and Toll-like Receptor 7/8 Agonist for Orchestrated Chemoimmunotherapy. Journal of Nanobiotechnology, 2022, 20(1), 369. doi: 10.1186/s12951-022-01577-5
  192. McMullen, A.; Muñoz Basagoiti, M.; Zeravcic, Z.; Brujic, J. Self-Assembly of Emulsion Droplets through Programmable Folding. Nature, 2022, 610(7932), 502–506. doi: 10.1038/s41586-022-05198-8
  193. Klimek, R.; Kaiser, C.; Murmann, N. S.; Kaltenschnee, N.; Spanò, T.; Wachtveitl, J.; Schuman, E. M.; Heckel, A. RNA Probes for Visualization of Sarcin/Ricin Loop Depurination without Background Fluorescence. Chemistry – An Asian Journal, 2022, 17(24), e202201077. doi: 10.1002/asia.202201077
  194. Gallicano, G. I.; Fu, J.; Mahapatra, S.; Sharma, M. V. R.; Dillon, C.; Deng, C.; Zahid, M. Reversing Cardiac Hypertrophy at the Source Using a Cardiac Targeting Peptide Linked to MiRNA106a: Targeting Genes That Cause Cardiac Hypertrophy. Pharmaceuticals, 2022, 15(7), 871. doi: 10.3390/ph15070871
  195. Sakhabutdinova, A. R.; Gazizov, R. R.; Chemeris, A. V.; Garafutdinov, R. R. Reverse Transcriptase-Free Detection of Viral RNA Using Hemo Klentaq DNA Polymerase. Analytical Biochemistry, 2022, 659, 114960.. doi: 10.1016/j.ab.2022.114960
  196. Chattaraj, R.; Kim, C. Y.; Lee, D.; Hammer, D. A. Recombinant Protein Micelles to Block Transduction by SARS-CoV-2 Pseudovirus. ACS Nano, 2022, 16(10), 17466–17477. doi: 10.1021/acsnano.2c09015
  197. Wang, P.; Moreno, S.; Janke, A.; Boye, S.; Wang, D.; Schwarz, S.; Voit, B.; Appelhans, D. Probing Crowdedness of Artificial Organelles by Clustering Polymersomes for Spatially Controlled and PH-Triggered Enzymatic Reactions. Biomacromolecules, 2022, 23(9), 3648–3662. doi: 10.1021/acs.biomac.2c00546
  198. Tang, Y.-J.; Zhou, D.-Y.; Dai, J.; Li, Y.; Xing, Y.-M.; Guo, S.-X.; Chen, J. Potential Specificity Between Mycorrhizal Fungi Isolated from Widespread Dendrobium Spp. and Rare D. Huoshanense Seeds. Curr Microbiol, 2022, 79(9), 264. doi: 10.1007/s00284-022-02952-z
  199. Hagen, R.; Fehr, D.; Spano, F.; Brambilla, D.; Bonmarin, M. Portable Multi-Wavelength Fluorescence Measurement Device. 2022 IEEE International Symposium on Medical Measurements and Applications (MeMeA), 2022, 1-6. doi: 10.1109/MeMeA54994.2022.9856591
  200. Jeong, M.; Jung, Y.; Yoon, J.; Kang, J.; Lee, S. H.; Back, W.; Kim, H.; Sailor, M. J.; Kim, D.; Park, J.-H. Porous Silicon-Based Nanomedicine for Simultaneous Management of Joint Inflammation and Bone Erosion in Rheumatoid Arthritis. ACS Nano, 2022, 16(10), 16118–16132. doi: 10.1021/acsnano.2c04491.
  201. Yu, H.; Palazzolo, J. S.; Ju, Y.; Niego, B.; Pan, S.; Hagemeyer, C. E.; Caruso, F. Polyphenol-Functionalized Cubosomes as Thrombolytic Drug Carriers. Advanced Healthcare Materials, 2022, 11(21), 2201151. doi: 10.1002/adhm.202201151
  202. Hu, Y.; Wang, Y.; Singh, J.; Sun, R.; Xu, L.; Niu, X.; Huang, K.; Bai, G.; Liu, G.; Zuo, X.; Chen, C.; Qin, P. Z.; Fang, X. Phosphorothioate-Based Site-Specific Labeling of Large RNAs for Structural and Dynamic Studies. ACS Chem. Biol., 2022, 17(9), 2448–2460. doi: 10.1021/acschembio.2c00199
  203. Cathcart, J.; Suarato, G.; Li, W.; Cao, J.; Meng, Y. Peptide-Functionalized Nanoparticles for the Targeted Delivery of Cytotoxins to MMP-14-Expressing Cancer Cells. Biophysica, 2022, 2(3), 203–220. doi: 10.3390/biophysica2030021
  204. Almeida, S. F. F.; Fonseca, A.; Sereno, J.; Ferreira, H. R. S.; Lapo-Pais, M.; Martins-Marques, T.; Rodrigues, T.; Oliveira, R. C.; Miranda, C.; Almeida, L. P.; Girão, H.; Falcão, A.; Abrunhosa, A. J.; Gomes, C. M. Osteosarcoma-Derived Exosomes as Potential PET Imaging Nanocarriers for Lung Metastasis. Small, 2022, 18(49), 2203999. doi: 10.1002/smll.202203999
  205. Almeida, A.; Castro, F.; Resende, C.; Lúcio, M.; Schwartz, S.; Sarmento, B. Oral Delivery of Camptothecin-Loaded Multifunctional Chitosan-Based Micelles Is Effective in Reduce Colorectal Cancer. Journal of Controlled Release, 2022, 349, 731–743. doi: 10.1016/j.jconrel.2022.07.029
  206. Chen, Y.; Wang, Y.; Chen, Z.; Cai, J.; Li, K.; Huang, H.; Song, F.; Gao, M.; Yang, Y.; Zheng, L.; Zhao, J. NIR-Driven Polydopamine-Based Nanoenzymes as ROS Scavengers to Suppress Osteoarthritis Progression. Materials Today Nano, 2022, 19, 100240. doi: 10.1016/j.mtnano.2022.100240
  207. Zhang, F.; Zhuang, J.; Li, Z.; Gong, H.; de Ávila, B. E.-F.; Duan, Y.; Zhang, Q.; Zhou, J.; Yin, L.; Karshalev, E.; Gao, W.; Nizet, V.; Fang, R. H.; Zhang, L.; Wang, J. Nanoparticle-Modified Microrobots for in Vivo Antibiotic Delivery to Treat Acute Bacterial Pneumonia. Nat. Mater., 2022, 21(11), 1324–1332. doi: 10.1038/s41563-022-01360-9
  208. Liu, H.; Wen, Z.; Chen, H.; Yang, Z.; Le, Z.; Liu, Z.; Chen, Y.; Liu, L. Nanoadjuvants Actively Targeting Lymph Node Conduits and Blocking Tumor Invasion in Lymphatic Vessels. Journal of Controlled Release, 2022, 352, 497–506. doi: 0.1016/j.jconrel.2022.10.053
  209. Mills, C. E.; Subramanian, K.; Hafner, M.; Niepel, M.; Gerosa, L.; Chung, M.; Victor, C.; Gaudio, B.; Yapp, C.; Nirmal, A. J.; Clark, N.; Sorger, P. K. Multiplexed and Reproducible High Content Screening of Live and Fixed Cells Using Dye Drop. Nature Communications, 2022, 13(1), 6918. doi: 10.1038/s41467-022-34536-7
  210. Zhang, Y.; Sriramaneni, R. N.; Clark, P. A.; Jagodinsky, J. C.; Ye, M.; Jin, W.; Wang, Y.; Bates, A.; Kerr, C. P.; Le, T.; Allawi, R.; Wang, X.; Xie, R.; Havighurst, T. C.; Chakravarty, I.; Rakhmilevich, A. L.; O’Leary, K. A.; Schuler, L. A.; Sondel, P. M.; Kim, K.; Gong, S.; Morris, Z. S. Multifunctional Nanoparticle Potentiates the in Situ Vaccination Effect of Radiation Therapy and Enhances Response to Immune Checkpoint Blockade. Nat Commun, 2022, 13(1), 4948. doi: 10.1038/s41467-022-32645-x
  211. Semenova, D.; Zabirnyk, A.; Lobov, A.; Boyarskaya, N.; Kachanova, O.; Uspensky, V.; Zainullina, B.; Denisov, E.; Gerashchenko, T.; Kvitting, J.-P. E.; Kaljusto, M.-L.; Thiede, B.; Kostareva, A.; Stensløkken, K.-O.; Vaage, J.; Malashicheva, A. Multi-Omics of in Vitro Aortic Valve Calcification. Frontiers in Cardiovascular Medicine, 2022, 9, 1043165. doi: 10.3389/fcvm.2022.1043165
  212. New, E. J. Molecular Fluorescent Sensors for Cellular Studies. John Wiley & Sons, 2022
  213. Luu, B. E.; Mossa, A. H.; Cammisotto, P. G.; Uri Saragovi, H.; Campeau, L. Modulation of Diabetic Kidney Disease Markers by an Antagonist of P75NTR in Streptozotocin-Treated Mice. Gene, 2022, 838, 146729. doi: 10.1016/j.gene.2022.146729
  214. Mills, J. A.; Humphries, J.; Simpson, J. D.; Sonderegger, S. E.; Thurecht, K. J.; Fletcher, N. L. Modulating Macrophage Clearance of Nanoparticles: Comparison of Small-Molecule and Biologic Drugs as Pharmacokinetic Modifiers of Soft Nanomaterials. Mol. Pharmaceutics, 2022, 19(11), 4080–4097. doi: 10.1021/acs.molpharmaceut.2c00528
  215. Ong, S. C.; Belgi, A.; Merriman, A. L.; Delaine, C. A.; van Lierop, B.; Andrikopoulos, S.; Robinson, A. J.; Forbes, B. E. Minimizing Mitogenic Potency of Insulin Analogues Through Modification of a Disulfide Bond. Front Endocrinol (Lausanne), 2022, 13, 907864. doi: 10.3389/fendo.2022.907864
  216. Hoque, J.; Zeng, Y.; Newman, H.; Gonzales, G.; Lee, C.; Varghese, S. Microgel-Assisted Delivery of Adenosine to Accelerate Fracture Healing. ACS Biomater. Sci. Eng., 2022, 8(11), 4863–4872. doi: 10.1021/acsbiomaterials.2c00977
  217. Chung, Y. H.; Volckaert, B. A.; Steinmetz, N. F. Metastatic Colon Cancer Treatment Using S100A9-Targeted Cowpea Mosaic Virus Nanoparticles. Biomacromolecules, 2022, 23(12), 5127–5136. doi: 10.1021/acs.biomac.2c00873
  218. Liu, N.; Yang, C.; Liang, X.; Cao, K.; Xie, J.; Luo, Q.; Luo, H. Mesoporous Silica Nanoparticle-Encapsulated Bifidobacterium Attenuates Brain Aβ Burden and Improves Olfactory Dysfunction of APP/PS1 Mice by Nasal Delivery. Journal of Nanobiotechnology, 2022, 20(1), 439. doi: 10.1186/s12951-022-01642-z
  219. Brodszkij, E.; Westensee, I. N.; Holleufer, S. F.; Ade, C.; Andres, P. D. D.; Pedersen, J. S.; Städler, B. Membrane Composition of Polymer-Lipid Hybrid Vesicles. Applied Materials Today, 2022, 29, 101549. doi: 10.1016/j.apmt.2022.101549
  220. Backes, I. M.; Byrd, B. K.; Slein, M. D.; Patel, C. D.; Taylor, S. A.; Garland, C. R.; MacDonald, S. W.; Balazs, A. B.; Davis, S. C.; Ackerman, M. E.; Leib, D. A. Maternally Transferred MAbs Protect Neonatal Mice from HSV-Induced Mortality and Morbidity. Journal of Experimental Medicine, 2022, 219(12), e20220110. doi: 10.1084/jem.20220110
  221. Boehnke, N.; Straehla, J. P.; Safford, H. C.; Kocak, M.; Rees, M. G.; Ronan, M.; Rosenberg, D.; Adelmann, C. H.; Chivukula, R. R.; Nabar, N.; Berger, A. G.; Lamson, N. G.; Cheah, J. H.; Li, H.; Roth, J. A.; Koehler, A. N.; Hammond, P. T. Massively Parallel Pooled Screening Reveals Genomic Determinants of Nanoparticle Delivery. Science, 2022, 377(6604), eabm5551. doi: 10.1126/science.abm5551
  222. Bulgakova, A.; Chubarov, A.; Dmitrienko, E. Magnetic Nylon 6 Nanocomposites for the Microextraction of Nucleic Acids from Biological Samples. Magnetochemistry, 2022, 8(8), 85. doi: 10.3390/magnetochemistry8080085
  223. Sapach, A. Yu.; Sindeeva, O. A.; Nesterchuk, M. V.; Tsitrina, A. A.; Mayorova, O. A.; Prikhozhdenko, E. S.; Verkhovskii, R. A.; Mikaelyan, A. S.; Kotelevtsev, Y. V.; Sukhorukov, G. B. Macrophage In Vitro and In Vivo Tracking via Anchored Microcapsules. ACS Appl. Mater. Interfaces, 2022, 14(46), 51579–51592. doi: 10.1021/acsami.2c12004
  224. Toporkova, Y. Y.; Smirnova, E. O.; Mukhtarova, L. S.; Grechkin, A. N. Lipoxygenase Pathway in Brown Algae: The Biosynthesis of Novel Oxylipins ‘Ectocarpins’ by Hydroperoxide Bicyclase CYP5164A3 of Ectocarpus Siliculosus. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2022, 1867(10), 159205. doi: 10.1016/j.bbalip.2022.159205
  225. Chatterjee, S.; Maltseva, D.; Kan, Y.; Hosseini, E.; Gonella, G.; Bonn, M.; Parekh, S. H. Lipid-Driven Condensation and Interfacial Ordering of FUS. Science Advances, 2022, 8(31), eabm7528. doi: 10.1126/sciadv.abm7528
  226. Khan, S. H.; Braet, S. M.; Koehler, S. J.; Elacqua, E.; Anand, G. S.; Okafor, C. D. Ligand-Induced Shifts in Conformational Ensembles That Describe Transcriptional Activation. eLife, 2022, 11, e80140. doi: 0.7554/eLife.80140
  227. Levina, A.; Repkova, M.; Kupryushkin, M.; Seryapina, A.; Shevelev, O.; Pyshnyi, D.; Zarytova, V.; Markel, A. In Vivo Hypotensive Effect of Aminosilanol-Based Nanocomposites Bearing Antisense Oligonucleotides. Journal of Drug Delivery Science and Technology, 2022, 75, 103612. doi: 10.1016/j.jddst.2022.103612
  228. Affonso de Oliveira, J. F.; Chan, S. K.; Omole, A. O.; Agrawal, V.; Steinmetz, N. F. In Vivo Fate of Cowpea Mosaic Virus In Situ Vaccine: Biodistribution and Clearance. ACS Nano, 2022, 16(11), 18315–18328. doi: 10.1021/acsnano.2c06143
  229. Khrenova, M.; Nikiforova, L.; Grabovenko, F.; Orlova, N.; Sinegubova, M.; Kolesov, D.; Zavyalova, E.; Spiridonova, V.; Zatsepin, T.; Zvereva, M. In Vitro Selection of an Aptamer Targeting SARS-CoV-2 Spike Protein with Nanopore Sequence Identification Reveals Discrimination Between the Authentic Strain and Omicron. ChemRxiv, 2022, preprint. doi: 10.26434/chemrxiv-2022-d9gcs
  230. Serda, M.; Malarz, K.; Korzuch, J.; Szubka, M.; Zubko, M.; Musioł, R. In Situ Cellular Localization of Nonfluorescent [60]Fullerene Nanomaterial in MCF-7 Breast Cancer Cells. ACS Biomater. Sci. Eng., 2022, 8(8), 3450–3462. doi: 10.1021/acsbiomaterials.2c00542
  231. Zhang, Y.; Xu, K.; Zhi, D.; Qian, M.; Liu, K.; Shuai, Q.; Qin, Z.; Xie, J.; Wang, K.; Yang, J. Improving Vascular Regeneration Performance of Electrospun Poly(ε-Caprolactone) Vascular Grafts via Synergistic Functionalization with VE-Cadherin/VEGF. Adv. Fiber Mater., 2022, 4(6), 1685–1702. doi: 10.1007/s42765-022-00213-z
  232. Kanamaru, T.; Sakurai, K.; Fujii, S. Impact of Polyethylene Glycol (PEG) Conformations on the In Vivo Fate and Drug Release Behavior of PEGylated Core-Cross-Linked Polymeric Nanoparticles. Biomacromolecules, 2022, 23(9), 3909–3918. doi: 10.1021/acs.biomac.2c00730
  233. Lu, Y.; Huntoon, K.; Lee, D.; Wang, Y.; Ha, J.; Qie, Y.; Li, X.; Schrank, B. R.; Dong, S.; Gallup, T. D.; Kang, M.; Zhao, H.; An, Y.; Yang, Z.; Li, J.; Kim, B. Y. S.; Jiang, W. Immunological Conversion of Solid Tumours Using a Bispecific Nanobioconjugate for Cancer Immunotherapy. Nat. Nanotechnol., 2022, 17(12), 1332–1341. doi: 10.1038/s41565-022-01245-7
  234. Bonova, P.; Koncekova, J.; Nemethova, M.; Petrova, K.; Bona, M.; Gottlieb, M. Identification of Proteins Responsible for the Neuroprotective Effect of the Secretome Derived from Blood Cells of Remote Ischaemic Conditioned Rats. Biomolecules, 2022, 12(10), 1423. doi: 10.3390/biom12101423
  235. Samuelian, J. S.; Baum, D. A. Identification of DNA Aptamers for Benzodiazepine Detection in Synthetic Urine. Analysis & Sensing, 2022, 2(6), e202200044. doi: 10.1002/anse.202200044
  236. Xu, J.; Chen, P.; Yu, C.; Shi, Q.; Wei, S.; Li, Y.; Qi, H.; Cao, Q.; Guo, C.; Wu, X.; Di, G. Hypoxic Bone Marrow Mesenchymal Stromal Cells-Derived Exosomal MiR-182-5p Promotes Liver Regeneration via FOXO1-Mediated Macrophage Polarization. The FASEB Journal, 2022, 36(10), e22553. doi: 10.1096/fj.202101868RRR
  237. Mahmoud, A. M.; Nowell, C. J.; Feeney, O.; van ’t Hag, L.; Davis, T. P.; Kempe, K. Hydrophobicity Regulates the Cellular Interaction of Cyanine5-Labeled Poly(3-Hydroxypropionate)-Based Comb Polymers. Biomacromolecules, 2022, 23(9), 3560–3571. doi: 10.1021/acs.biomac.2c00303
  238. Shvindelman, O.; Nordling-David, M. M.; Grad, E.; Golomb, G. Harnessing Monocytes for a Liposomal Rosiglitazone-Mediated Anti-Inflammatory Effect. Precision Nanomedicine, 2022, 5(4), 930–945. doi: 10.33218/001c.38312
  239. Phan, H.; Cavanagh, R.; Destouches, D.; Vacherot, F.; Brissault, B.; Taresco, V.; Penelle, J.; Couturaud, B. H2O2-Responsive Nanocarriers Prepared by RAFT-Mediated Polymerization-Induced Self-Assembly of N-(2-(Methylthio)Ethyl)Acrylamide for Biomedical Applications. ACS Appl. Polym. Mater., 2022, 4(10), 7778–7789. doi: 10.1021/acsapm.2c01327
  240. Quarta, C.; Stemmer, K.; Novikoff, A.; Yang, B.; Klingelhuber, F.; Harger, A.; Bakhti, M.; Bastidas-Ponce, A.; Baugé, E.; Campbell, J. E.; Capozzi, M.; Clemmensen, C.; Collden, G.; Cota, P.; Douros, J.; Drucker, D. J.; DuBois, B.; Feuchtinger, A.; Garcia-Caceres, C.; Grandl, G.; Hennuyer, N.; Herzig, S.; Hofmann, S. M.; Knerr, P. J.; Kulaj, K.; Lalloyer, F.; Lickert, H.; Liskiewicz, A.; Liskiewicz, D.; Maity, G.; Perez-Tilve, D.; Prakash, S.; Sanchez-Garrido, M. A.; Zhang, Q.; Staels, B.; Krahmer, N.; DiMarchi, R. D.; Tschöp, M. H.; Finan, B.; Müller, T. D. GLP-1-Mediated Delivery of Tesaglitazar Improves Obesity and Glucose Metabolism in Male Mice. Nat Metab, 2022, 4(8), 1071–1083. doi: 10.1038/s42255-022-00617-6
  241. Duskey, J. T.; Rinaldi, A.; Ottonelli, I.; Caraffi, R.; De Benedictis, C. A.; Sauer, A. K.; Tosi, G.; Vandelli, M. A.; Ruozi, B.; Grabrucker, A. M. Glioblastoma Multiforme Selective Nanomedicines for Improved Anti-Cancer Treatments. Pharmaceutics, 2022, 14(7), 1450. doi: 10.3390/pharmaceutics14071450
  242. Zhang, F.; Li, Z.; Duan, Y.; Abbas, A.; Mundaca-Uribe, R.; Yin, L.; Luan, H.; Gao, W.; Fang, R. H.; Zhang, L.; Wang, J. Gastrointestinal Tract Drug Delivery Using Algae Motors Embedded in a Degradable Capsule. Science Robotics, 2022, 7(70), eabo4160. doi: 10.1126/scirobotics.abo4160
  243. Morozov, V. N.; Klimovich, M. A.; Kostyukov, A. A.; Belousov, A. V.; Kolyvanova, M. A.; Nekipelova, T. D.; Kuzmin, V. A. Förster Resonance Energy Transfer from Hoechst 33258 to SYBR Green I in Cholesteric Liquid-Crystalline DNA. Journal of Luminescence, 2022, 252, 119381. doi: 10.1016/j.jlumin.2022.119381
  244. Chetverikov, P. E.; Bertone, M. A. First Rhyncaphytoptine Mite (Eriophyoidea, Diptilomiopidae) Parasitizing American Hazelnut (Corylus Americana): Molecular Identification, Confocal Microscopy, and Phylogenetic Position. Exp Appl Acarol, 2022, 88(1), 75–95. doi: 10.1007/s10493-022-00740-9
  245. Mekhail, K.; Lee, M.; Sugiyama, M.; Astori, A.; St-Germain, J.; Latreille, E.; Khosraviani, N.; Wei, K.; Li, Z.; Rini, J.; Lee, W. L.; Antonescu, C.; Raught, B.; Fairn, G. D. FASN Inhibitor TVB-3166 Prevents S-Acylation of the Spike Protein of Human Coronaviruses. Journal of Lipid Research, 2022, 63(9), 100256. doi: 10.1016/j.jlr.2022.100256
  246. Britton, B. M.; London, J. A.; Martin-Lopez, J.; Jones, N. D.; Liu, J.; Lee, J.-B.; Fishel, R. Exploiting the Distinctive Properties of the Bacterial and Human MutS Homolog Sliding Clamps on Mismatched DNA. Journal of Biological Chemistry, 2022, 298(11), 102505. doi: 10.1016/j.jbc.2022.102505
  247. Garcia Maset, R.; Hapeshi, A.; Hall, S.; Dalgliesh, R. M.; Harrison, F.; Perrier, S. Evaluation of the Antimicrobial Activity in Host-Mimicking Media and In Vivo Toxicity of Antimicrobial Polymers as Functional Mimics of AMPs. ACS Appl. Mater. Interfaces, 2022, 14(29), 32855–32868. doi: 10.1021/acsami.2c05979
  248. Naeimipour, S.; Rasti Boroojeni, F.; Selegård, R.; Aili, D. Enzymatically Triggered Deprotection and Cross-Linking of Thiolated Alginate-Based Bioinks. Chem. Mater., 2022, 34(21), 9536–9545. doi: 10.1021/acs.chemmater.2c02037
  249. Lee, S. E.; Lee, C. M.; Won, J. E.; Jang, G.-Y.; Lee, J. H.; Park, S. H.; Kang, T. H.; Han, H. D.; Park, Y.-M. Enhancement of Anticancer Immunity by Immunomodulation of Apoptotic Tumor Cells Using Annexin A5 Protein-Labeled Nanocarrier System. Biomaterials, 2022, 288, 121677. doi: 10.1016/j.biomaterials.2022.121677
  250. Dragulska, S. A.; Poursharifi, M.; Chen, Y.; Wlodarczyk, M. T.; Acosta Santiago, M.; Dottino, P.; Martignetti, J. A.; Mieszawska, A. J. Engineering and Validation of a Peptide-Stabilized Poly(Lactic-Co-Glycolic) Acid Nanoparticle for Targeted Delivery of a Vascular Disruptive Agent in Cancer Therapy. Bioconjugate Chem., 2022, 33(12), 2348–2360. doi: 10.1021/acs.bioconjchem.2c00418
  251. Chernyshev, V. S.; Nozdriukhin, D.; Chuprov-Netochin, R.; Tsydenzhapova, E.; Novoselova, M.; Gorin, D.; Yashchenok, A. Engineered Multicompartment Vesicosomes for Selective Uptake by Living Cells. Colloids and Surfaces B: Biointerfaces, 2022, 220, 112953. doi: 10.1016/j.colsurfb.2022.112953
  252. Hao, D.; Lu, L.; Song, H.; Duan, Y.; Chen, J.; Carney, R.; Li, J. J.; Zhou, P.; Nolta, J.; Lam, K. S.; Leach, J. K.; Farmer, D. L.; Panitch, A.; Wang, A. Engineered Extracellular Vesicles with High Collagen-Binding Affinity Present Superior in Situ Retention and Therapeutic Efficacy in Tissue Repair. Theranostics, 2022, 12(13), 6021–6037. doi: 10.7150/thno.70448
  253. Manspeaker, M. P.; O’Melia, M. J.; Thomas, S. N. Elicitation of Stem-like CD8+ T Cell Responses via Lymph Node-Targeted Chemoimmunotherapy Evokes Systemic Tumor Control. J Immunother Cancer, 2022, 10(9), e005079. doi: 10.1136/jitc-2022-005079
  254. Santos-Coquillat, A.; Herreros-Pérez, D.; Samaniego, R.; González, M. I.; Cussó, L.; Desco, M.; Salinas, B. Dual-Labeled Nanoparticles Based on Small Extracellular Vesicles for Tumor Detection. Biol Direct, 2022, 17(1), 31. doi: 10.1186/s13062-022-00345-7
  255. Xu, S.; Zhang, P.; Heing-Becker, I.; Zhang, J.; Tang, P.; Bej, R.; Bhatia, S.; Zhong, Y.; Haag, R. Dual Tumor- and Subcellular-Targeted Photodynamic Therapy Using Glucose-Functionalized MoS2 Nanoflakes for Multidrug-Resistant Tumor Ablation. Biomaterials, 2022, 290, 121844. doi: 10.1016/j.biomaterials.2022.121844
  256. Wiemann, J. T.; Nguyen, D.; Li, Y.; Yu, Y. Domain-Selective Disruption and Compression of Phase-Separated Lipid Vesicles by Amphiphilic Janus Nanoparticles. iScience, 2022, 25(12), 105525. doi: 10.1016/j.isci.2022.105525
  257. Kang, K.; Shi, Q.; Wang, X.; Chen, Y.-G. Dishevelled Phase Separation Promotes Wnt Signalosome Assembly and Destruction Complex Disassembly. Journal of Cell Biology, 2022, 221(12), e202205069. doi: 10.1083/jcb.202205069
  258. McGuire, C. C.; Robert, J. R. Developmental Exposure to Thyroid Disrupting Chemical Mixtures Alters Metamorphosis and Post-Metamorphic Thymocyte Differentiation. Current Research in Toxicology, 2022, 3, 100094. doi: 10.1016/j.crtox.2022.100094
  259. Cheng, A. G.; Ho, P.-Y.; Aranda-Díaz, A.; Jain, S.; Yu, F. B.; Meng, X.; Wang, M.; Iakiviak, M.; Nagashima, K.; Zhao, A.; Murugkar, P.; Patil, A.; Atabakhsh, K.; Weakley, A.; Yan, J.; Brumbaugh, A. R.; Higginbottom, S.; Dimas, A.; Shiver, A. L.; Deutschbauer, A.; Neff, N.; Sonnenburg, J. L.; Huang, K. C.; Fischbach, M. A. Design, Construction, and in Vivo Augmentation of a Complex Gut Microbiome. Cell, 2022, 185(19), 3617-3636.e19. doi: 10.1016/j.cell.2022.08.003
  260. Carraro, C.; Bonaguro, L.; Schulte-Schrepping, J.; Horne, A.; Oestreich, M.; Warnat-Herresthal, S.; Helbing, T.; De Franco, M.; Haendler, K.; Mukherjee, S.; Ulas, T.; Gandin, V.; Goettlich, R.; Aschenbrenner, A. C.; Schultze, J. L.; Gatto, B. Decoding Mechanism of Action and Sensitivity to Drug Candidates from Integrated Transcriptome and Chromatin State. eLife, 2022, 11, e78012. doi: 10.7554/eLife.78012
  261. Nakamura, M.; Fujiwara, K.; Doi, N. Cytoplasmic Delivery of SiRNA Using Human-Derived Membrane Penetration-Enhancing Peptide. Journal of Nanobiotechnology, 2022, 20(1), 458. doi: 10.1186/s12951-022-01667-4
  262. Chen, Q.; Menon, R.; Calder, L. J.; Tolar, P.; Rosenthal, P. B. Cryomicroscopy Reveals the Structural Basis for a Flexible Hinge Motion in the Immunoglobulin M Pentamer. Nat Commun, 2022, 13(1), 6314. doi: 10.1038/s41467-022-34090-2
  263. Futamata, H.; Fukuda, M.; Umeda, R.; Yamashita, K.; Tomita, A.; Takahashi, S.; Shikakura, T.; Hayashi, S.; Kusakizako, T.; Nishizawa, T.; Homma, K.; Nureki, O. Cryo-EM Structures of Thermostabilized Prestin Provide Mechanistic Insights Underlying Outer Hair Cell Electromotility. Nat Commun, 2022, 13(1), 6208. doi: 10.1038/s41467-022-34017-x
  264. Pauwels, M. J.; Xie, J.; Ceroi, A.; Balusu, S.; Castelein, J.; Van Wonterghem, E.; Van Imschoot, G.; Ward, A.; Menheniott, T. R.; Gustafsson, O.; Combes, F.; EL Andaloussi, S.; Sanders, N. N.; Mäger, I.; Van Hoecke, L.; Vandenbroucke, R. E. Choroid Plexus-Derived Extracellular Vesicles Exhibit Brain Targeting Characteristics. Biomaterials, 2022, 290, 121830. doi: 10.1016/j.biomaterials.2022.121830
  265. Liu, B.; Zhuang, S.; Tian, R.; Liu, Y.; Wang, Y.; Lei, X.; Wang, C. Chemoproteomic Profiling Reveals the Mechanism of Bile Acid Tolerance in Bacteria. ACS Chem. Biol., 2022, 17(9), 2461–2470. doi: 10.1021/acschembio.2c00286
  266. Gantsova, E. A.; Gavrilenkova, A. A.; Serova, O. V.; Deyev, I. E. Changes in the Expression of the Gapdh Gene in the Organs of Insrr Knockout Mice. Dokl Biol Sci, 2022, 505(1), 113–118. doi: 10.1134/S0012496622040056
  267. Schaal, J. L.; Bhattacharyya, J.; Brownstein, J.; Strickland, K. C.; Kelly, G.; Saha, S.; Milligan, J.; Banskota, S.; Li, X.; Liu, W.; Kirsch, D. G.; Zalutsky, M. R.; Chilkoti, A. Brachytherapy via a Depot of Biopolymer-Bound 131I Synergizes with Nanoparticle Paclitaxel in Therapy-Resistant Pancreatic Tumours. Nat. Biomed. Eng., 2022, 6(10), 1148–1166. doi: 10.1038/s41551-022-00949-4
  268. Costabile, G.; Mitidieri, E.; Visaggio, D.; Provenzano, R.; Miro, A.; Quaglia, F.; d’Angelo, I.; Frangipani, E.; Sorrentino, R.; Visca, P.; d’Emmanuele di Villa Bianca, R.; Ungaro, F. Boosting Lung Accumulation of Gallium with Inhalable Nano-Embedded Microparticles for the Treatment of Bacterial Pneumonia. International Journal of Pharmaceutics, 2022, 629, 122400. doi: 10.1016/j.ijpharm.2022.122400
  269. Zeng, Y.; Shen, Y.; Wu, S.; Cai, L.; Wang, Z.; Cai, K.; Shen, J.; Hii Ru Yie, K.; Zhang, H.; Xu, L.; Liu, J. Bone-Targeting PLGA Derived Lipid Drug Delivery System Ameliorates Bone Loss in Osteoporotic Ovariectomized Rats. Materials & Design, 2022, 221, 110967. doi: 10.1016/j.matdes.2022.110967
  270. Grossenbacher, P.; C. Essers, M.; Moser, J.; A. Singer, S.; Häusler, S.; Stieger, B.; Rougier, J.-S.; Lochner, M. Bioorthogonal Site-Selective Conjugation of Fluorescent Dyes to Antibodies: Method and Potential Applications. RSC Advances, 2022, 12(44), 28306–28317. doi: 10.1039/D2RA05580E
  271. Egorova, D. A.; Solovyev, A. I.; Polyakov, N. B.; Danilova, K. V.; Scherbakova, A. A.; Kravtsov, I. N.; Dmitrieva, M. A.; Rykova, V. S.; Tutykhina, I. L.; Romanova, Y. M.; Gintsburg, A. L. Biofilm Matrix Proteome of Clinical Strain of P. Aeruginosa Isolated from Bronchoalveolar Lavage of Patient in Intensive Care Unit. Microbial Pathogenesis, 2022, 170, 105714. doi: 10.1016/j.micpath.2022.105714
  272. Bodin, J.-B.; Gateau, J.; Coïs, J.; Lucas, T.; Lefebvre, F.; Moine, L.; Noiray, M.; Cailleau, C.; Denis, S.; Clavier, G.; Tsapis, N.; Méallet-Renault, R. Biocompatible and Photostable Photoacoustic Contrast Agents as Nanoparticles Based on Bodipy Scaffold and Polylactide Polymers: Synthesis, Formulation, and In Vivo Evaluation. ACS Appl. Mater. Interfaces, 2022, 14(36), 40501–40512. doi: 10.1021/acsami.2c04874
  273. Grzelak, J.; Teles, M.; Roher, N.; Grayston, A.; Rosell, A.; Gich, M.; Roig, A. Bioevaluation of Magnetic Mesoporous Silica Rods: Cytotoxicity, Cell Uptake and Biodistribution in Zebrafish and Rodents. RSC Advances, 2022, 12(49), 31878–31888. doi: 10.1039/D2RA05750F
  274. Abakumova, T. O.; Gusliakova, O. I.; Cvjetinovic, J.; Efimova, O. I.; Konovalova, E. V.; Schulga, A. A.; Zatsepin, T. S.; Gorin, D. A.; Yashchenok, A. M.; Deyev, S. M. Barnase-Loaded Vaterite Nanoparticles Functionalized by EpCAM Targeting Vectors for the Treatment of Lung Diseases. ACS Appl. Nano Mater., 2022, 5(8), 10744–10754. doi: 10.1021/acsanm.2c02078
  275. Baharlou, H.; Canete, N.; Vine, E. E.; Hu, K.; Yuan, D.; Sandgren, K. J.; Bertram, K. M.; Nasr, N.; Rhodes, J. W.; Gosselink, M. P.; Di Re, A.; Reza, F.; Ctercteko, G.; Pathma-Nathan, N.; Collins, G.; Toh, J.; Patrick, E.; Haniffa, M. A.; Estes, J. D.; Byrne, S. N.; Cunningham, A. L.; Harman, A. N. An in Situ Analysis Pipeline for Initial Host-Pathogen Interactions Reveals Signatures of Human Colorectal HIV Transmission. Cell Reports, 2022, 40(12), 111385. doi: 10.1016/j.celrep.2022.111385
  276. Hu, C.; Ni, D.; Nam, K. H.; Majumdar, S.; McLean, J.; Stahlberg, H.; Terns, M. P.; Ke, A. Allosteric Control of Type I-A CRISPR-Cas3 Complexes and Establishment as Effective Nucleic Acid Detection and Human Genome Editing Tools. Molecular Cell, 2022, 82(15), 2754-2768.e5. doi: 10.1016/j.molcel.2022.06.007
  277. Abucayon, E. G.; Whalen, C.; Torres, O. B.; Duval, A. J.; Sulima, A.; Antoline, J. F. G.; Oertel, T.; Barrientos, R. C.; Jacobson, A. E.; Rice, K. C.; Matyas, G. R. A Rapid Method for Direct Quantification of Antibody Binding-Site Concentration in Serum. ACS Omega, 2022, 7(30), 26812–26823. doi: 10.1021/acsomega.2c03237
  278. Kolyvanova, M. A.; Klimovich, M. A.; Belousov, A. V.; Kuzmin, V. A.; Morozov, V. N. A Principal Approach to the Detection of Radiation-Induced DNA Damage by Circular Dichroism Spectroscopy and Its Dosimetric Application. Photonics, 2022, 9(11), 787. doi: 10.3390/photonics9110787
  279. Chen, H. H.; Khatun, Z.; Wei, L.; Mekkaoui, C.; Patel, D.; Kim, S. J. W.; Boukhalfa, A.; Enoma, E.; Meng, L.; Chen, Y. I.; Kaikkonen, L.; Li, G.; Capen, D. E.; Sahu, P.; Kumar, A. T. N.; Blanton, R. M.; Yuan, H.; Das, S.; Josephson, L.; Sosnovik, D. E. A Nanoparticle Probe for the Imaging of Autophagic Flux in Live Mice via Magnetic Resonance and Near-Infrared Fluorescence. Nat. Biomed. Eng, 2022, 6(9), 1045–1056. doi: 10.1038/s41551-022-00904-3
  280. He, J.-X.; Fei, Z.-C.; Fu, L.; Tian, C.-P.; He, F.-C.; Chi, H.; Yang, J. A Modification-Centric Assessment Tool for the Performance of Chemoproteomic Probes. Nat Chem Biol, 2022, 18(8), 904–912. doi: 10.1038/s41589-022-01074-8
  281. Miyazaki, T.; Chen, S.; Florinas, S.; Igarashi, K.; Matsumoto, Y.; Yamasoba, T.; Xu, Z.-Q.; Wu, H.; Gao, C.; Kataoka, K.; Christie, R. J.; Cabral, H. A Hoechst Reporter Enables Visualization of Drug Engagement In Vitro and In Vivo: Toward Safe and Effective Nanodrug Delivery. ACS Nano, 2022, 16(8), 12290–12304. doi: 10.1021/acsnano.2c03170
  282. Zhang, S.; Feng, Y.; Meng, M.; Li, Z.; Li, H.; Lin, L.; Xu, C.; Chen, J.; Hao, K.; Tang, Z.; Tian, H.; Chen, X. A Generally Minimalist Strategy of Constructing Biomineralized High-Efficiency Personalized Nanovaccine Combined with Immune Checkpoint Blockade for Cancer Immunotherapy. Biomaterials, 2022, 289, 121794. doi: 10.1016/j.biomaterials.2022.121794
  283. Kong, X.; Yan, K.; Deng, P.; Fu, H.; Sun, H.; Huang, W.; Jiang, S.; Dai, J.; Zhang, Q. C.; Liu, J. G.; Xi, Q. LncRNA-Smad7 Mediates Cross-Talk between Nodal/TGF-β and BMP Signaling to Regulate Cell Fate Determination of Pluripotent and Multipotent Cells. Nucleic Acids Research, 2022, 50(18), 10526–10543. doi: 10.1093/nar/gkac780
  284. Tran, T. T.; Vaage, E. B.; Mehta, A.; Chopra, A.; Tietze, L.; Kolderup, A.; Anthi, A.; König, M.; Nygaard, G.; Lind, A.; Müller, F.; Nissen-Meyer, L. S.; Magnus, P.; Trogstad, L.; Mjaaland, S.; Søraas, A.; Midtvedt, K.; Åsberg, A.; Barratt-Due, A.; Medhus, A. W.; Høivik, M. L.; Lundin, K.; Karlsen, R. F.; Dahle, R.; Danielsson, K.; Thomassen, K. S.; Kro, G. B.; Cox, R. J.; Zhou, F.; Langeland, N.; Aukrust, P.; Melum, E.; Åvitsland, T. L.; Wiencke, K.; Holter, J. C.; Munthe, L. A.; Grødeland, G.; Andersen, J.-T.; Vaage, J. T.; Lund-Johansen, F. Titers of Antibodies against Ancestral SARS-CoV-2 Correlate with Levels of Neutralizing Antibodies to Multiple Variants. npj Vaccines, 2022, 7(1), 174. doi: 10.1038/s41541-022-00586-7
  285. Ikonnikova, A.; Kazakov, R.; Rodina, T.; Dmitriev, A.; Melnikov, E.; Zasedatelev, A.; Nasedkina, T. The Influence of Structural Variants of the CES1 Gene on the Pharmacokinetics of Enalapril, Presumably Due to Linkage Disequilibrium with the Intronic Rs2244613. Genes, 2022, 13(12), 2225. doi: 10.3390/genes13122225
  286. Shanaa O.A.; Rumyantsev A.M.; Sambuk E.V.; Padkina M.V. The synthesis of Broccoli RNA fluorescent aptamer in  Saccharomyces cerevisiae  yeast cells. EcoGen, 2022, 20(4), 339–348. doi: 10.17816/ecogen111012
  287. Xiao, Y.; Pandey, K.; Nicolás-Boluda, A.; Onidas, D.; Nizard, P.; Carn, F.; Lucas, T.; Gateau, J.; Martin-Molina, A.; Quesada-Pérez, M.; del Mar Ramos-Tejada, M.; Gazeau, F.; Luo, Y.; Mangeney, C. Synergic Thermo- and PH-Sensitive Hybrid Microgels Loaded with Fluorescent Dyes and Ultrasmall Gold Nanoparticles for Photoacoustic Imaging and Photothermal Therapy. ACS Appl. Mater. Interfaces, 2022, 14(49), 54439–54457. doi: 10.1021/acsami.2c12796
  288. Afonin, D. A.; Geras’kina, O. V.; Loseva, T. V.; Kirpichnikov, M. P.; Studitsky, V. M.; Feofanov, A. V. Structure and Affinity of Complexes between the DNA-Binding Domain of Swi4 and DNA. Biophysics, 2022, 67(5), 700–707. doi: 10.1134/S0006350922050037
  289. Jo, M. H.; Li, J.; Jaumouillé, V.; Hao, Y.; Coppola, J.; Yan, J.; Waterman, C. M.; Springer, T. A.; Ha, T. Single-Molecule Characterization of Subtype-Specific Β1 Integrin Mechanics. Nature Communications, 2022, 13(1), 7471. doi: 10.1038/s41467-022-35173-w
  290. Jang, H.-J.; Yoon, Y. J.; Choi, J.; Lee, Y.-J.; Lee, S.; Cho, W.; Byun, W. G.; Park, S. B.; Han, D. C.; Kwon, B.-M. S-Benproperine, an Active Stereoisomer of Benproperine, Suppresses Cancer Migration and Tumor Metastasis by Targeting ARPC2. Pharmaceuticals, 2022, 15(12), 1462. doi: 10.3390/ph15121462
  291. Apostolos, A. J.; Chordia, M. D.; Kolli, S. H.; Dalesandro, B. E.; Rutkowski, M. R.; Pires, M. M. Real-Time Non-Invasive Fluorescence Imaging of Gut Commensal Bacteria to Detect Dynamic Changes in the Microbiome of Live Mice. Cell Chemical Biology, 2022, 29(12), 1721-1728.e5. doi: 10.1016/j.chembiol.2022.11.010
  292. Zhubanova, G.; Filchakova, O. RC-4BC Cells Express Nicotinic and Muscarinic Acetylcholine Receptors. PLOS ONE, 2022, 17(12), e0279284. doi: 10.1371/journal.pone.0279284
  293. Kostyunin, A.; Glushkova, T.; Lobov, A.; Ovcharenko, E.; Zainullina, B.; Bogdanov, L.; Shishkova, D.; Markova, V.; Asanov, M.; Mukhamadiyarov, R.; Velikanova, E.; Akentyeva, T.; Rezvova, M.; Stasev, A.; Evtushenko, A.; Barbarash, L.; Kutikhin, A. Proteolytic Degradation Is a Major Contributor to Bioprosthetic Heart Valve Failure. Journal of the American Heart Association, 2022, 12, e028215. doi: 10.1161/JAHA.122.028215
  294. Nevers, Q.; Scrima, N.; Glon, D.; Bars, R. L.; Decombe, A.; Garnier, N.; Ouldali, M.; Lagaudrière-Gesbert, C.; Blondel, D.; Albertini, A.; Gaudin, Y. Properties of Rabies Virus Phosphoprotein and Nucleoprotein Biocondensates Formed in Vitro and in Cellulo. PLOS Pathogens, 2022, 18(12), e1011022. doi: 10.1371/journal.ppat.1011022
  295. Park, Y.; Moses, A. S.; Demessie, A. A.; Singh, P.; Lee, H.; Korzun, T.; Taratula, O. R.; Alani, A. W. G.; Taratula, O. Poly(Aspartic Acid)-Based Polymeric Nanoparticle for Local and Systemic MRNA Delivery. Mol. Pharmaceutics, 2022, 19(12), 4696–4704. doi: 10.1021/acs.molpharmaceut.2c00738
  296. Yim, J.; Lee, J.; Yi, S.; Koo, J. Y.; Oh, S.; Park, H.; Kim, S. S.; Bae, M. A.; Park, J.; Park, S. B. Phenotype-Based Screening Rediscovered Benzopyran-Embedded Microtubule Inhibitors as Anti-Neuroinflammatory Agents by Modulating the Tubulin–P65 Interaction. Exp Mol Med, 2022, 54(12), 2200–2209. doi: 10.1038/s12276-022-00903-z
  297. Khvorova, I.; Kostina, D.; Zainullina, B.; Fefilova, E.; Gromova, E.; Tikhilov, R.; Bozhkova, S.; Sereda, A.; Karelkin, V.; Malashicheva, A.; Lobov, A. Osteogenic Differentiation In Vitro of Human Osteoblasts Is Associated with Only Slight Shift in Their Proteomics Profile. Cell and Tissue Biology, 2022, 16, 540–546. doi: 10.1134/S1990519X22060025
  298. Kitaura, Y.; Nakamura, U.; Awada, C.; Yamaguchi, M.; Kim, M.; Ikeda, Y.; Matsuo, Y.; Moriishi, T.; Sawase, T.; Chung, U.; Hojo, H.; Ohba, S. Orally Administrable Peptides Derived from Egg Yolk Promote Skeletal Repair and Ameliorate Degenerative Skeletal Disorders in Mouse Models. Regenerative Therapy, 2022, 21, 584–595. doi: 10.1016/j.reth.2022.11.002
  299. Ang, S.-T. J.; Crombie, E. M.; Dong, H.; Tan, K.-T.; Hernando, A.; Yu, D.; Adamson, S.; Kim, S.; Withers, D. J.; Huang, H.; Tsai, S.-Y. Muscle 4EBP1 Activation Modifies the Structure and Function of the Neuromuscular Junction in Mice. Nat Commun, 2022, 13(1), 7792. doi: 10.1038/s41467-022-35547-0
  300. Raducanu, V.-S.; Tehseen, M.; Al-Amodi, A.; Joudeh, L. I.; De Biasio, A.; Hamdan, S. M. Mechanistic Investigation of Human Maturation of Okazaki Fragments Reveals Slow Kinetics. Nature Communications, 2022, 13(1), 6973. doi: 10.1038/s41467-022-34751-2
  301. Zhang, F.; Li, Z.; Duan, Y.; Luan, H.; Yin, L.; Guo, Z.; Chen, C.; Xu, M.; Gao, W.; Fang, R. H.; Zhang, L.; Wang, J. Extremophile-Based Biohybrid Micromotors for Biomedical Operations in Harsh Acidic Environments. Science Advances, 2022, 8(51), eade6455. doi: 10.1126/sciadv.ade6455
  302. Schürz, M.; Danmayr, J.; Jaritsch, M.; Klinglmayr, E.; Benirschke, H. M.; Matea, C.-T.; Zimmerebner, P.; Rauter, J.; Wolf, M.; Gomes, F. G.; Kratochvil, Z.; Heger, Z.; Miller, A.; Heuser, T.; Stanojlovic, V.; Kiefer, J.; Plank, T.; Johnson, L.; Himly, M.; Blöchl, C.; Huber, C. G.; Hintersteiner, M.; Meisner-Kober, N. EVAnalyzer: High Content Imaging for Rigorous Characterisation of Single Extracellular Vesicles Using Standard Laboratory Equipment and a New Open-Source ImageJ/Fiji Plugin. Journal of Extracellular Vesicles, 2022, 11(12), 12282. doi: 10.1002/jev2.12282
  303. Nishiguchi, A.; Taguchi, T. Engineering Thixotropic Supramolecular Gelatin-Based Hydrogel as an Injectable Scaffold for Cell Transplantation. Biomed. Mater., 2022, 18(1), 015012. doi: 10.1088/1748-605X/aca501
  304. Kim, R. M.; Huh, J.-H.; Yoo, S.; Kim, T. G.; Kim, C.; Kim, H.; Han, J. H.; Cho, N. H.; Lim, Y.-C.; Im, S. W.; Im, E.; Jeong, J. R.; Lee, M. H.; Yoon, T.-Y.; Lee, H.-Y.; Park, Q.-H.; Lee, S.; Nam, K. T. Enantioselective Sensing by Collective Circular Dichroism. Nature, 2022, 612(7940), 470–476. doi: 10.1038/s41586-022-05353-1
  305. Shin, J. S.; Li, S. DNA-Immobilized Fluorescent Polystyrene Nanoparticles as Probes with Tunable Detection Limits. ACS Omega, 2022, 7(51), 48310–48319. doi: 10.1021/acsomega.2c06498
  306. Zhang, D.-X.; Tieu, T.; Esser, L.; Wojnilowicz, M.; Lee, C.-H.; Cifuentes-Rius, A.; Thissen, H.; Voelcker, N. H. Differential Surface Engineering Generates Core–Shell Porous Silicon Nanoparticles for Controlled and Targeted Delivery of an Anticancer Drug. ACS Appl. Mater. Interfaces, 2022, 14(49), 54539–54549. doi: 10.1021/acsami.2c16370
  307. Rabanel, J.-M.; Mirbagheri, M.; Olszewski, M.; Xie, G.; Le Goas, M.; Latreille, P.-L.; Counil, H.; Hervé, V.; Silva, R. O.; Zaouter, C.; Adibnia, V.; Acevedo, M.; Servant, M. J.; Martinez, V. A.; Patten, S. A.; Matyjaszewski, K.; Ramassamy, C.; Banquy, X. Deep Tissue Penetration of Bottle-Brush Polymers via Cell Capture Evasion and Fast Diffusion. ACS Nano, 2022, 16(12), 21583–21599. doi: 10.1021/acsnano.2c10554
  308. Hao, J.; Jin, R.; Zeng, J.; Hua, Y.; Yorek, M. S.; Liu, L.; Mandal, A.; Li, J.; Zheng, H.; Sun, Y.; Yi, Y.; Yin, D.; Zheng, Q.; Li, X.; Ng, C. K.; Rouchka, E. C.; Egilmez, N. K.; Jabbari, A.; Li, B. Consumption of Fish Oil High-Fat Diet Induces Murine Hair Loss via Epidermal Fatty Acid Binding Protein in Skin Macrophages. Cell Reports, 2022, 41(11), 111804. doi: 10.1016/j.celrep.2022.111804
  309. Garanina, A. S.; Efremova, M. V.; Machulkin, A. E.; Lyubin, E. V.; Vorobyeva, N. S.; Zhironkina, O. A.; Strelkova, O. S.; Kireev, I. I.; Alieva, I. B.; Uzbekov, R. E.; Agafonov, V. N.; Shchetinin, I. V.; Fedyanin, A. A.; Erofeev, A. S.; Gorelkin, P. V.; Korchev, Y. E.; Savchenko, A. G.; Abakumov, M. A. Bifunctional Magnetite–Gold Nanoparticles for Magneto-Mechanical Actuation and Cancer Cell Destruction. Magnetochemistry, 2022, 8(12), 185. doi: 10.3390/magnetochemistry8120185
  310. Budiardjo, S. J.; Stevens, J.J.; Calkins, A. L.; Ikujuni, A. P.; Wimalasena, V. K.; Firlar, E.; Case, D. A.; Biteen, J. S.; Kaelber, J. T.; Slusky, J. S.G. Colicin E1 Opens Its Hinge to Plug TolC. eLife, 2022, 11, e73297. doi: 10.7554/eLife.73297
  311. Singh, A.; Jothiprakasam, T.; Raghavan, J.V.; Jhunjhunwala, S. Sterile Inflammation Alters Neutrophil Kinetics in Mice. Journal of Leukocyte Biology, 2022, 112(3), 395-409. doi: 10.1002/JLB.1A0321-132RR
  312. Lee, M.S.; Hyun, H.; Park, I.; Kim, S.; Jang, D.-H.; Kim, S.; Im, J.-K.; Kim, H.; Lee, J.H.; Kwon, T.; Kang, J.H. Quantitative fluorescence in situ hybridization (FISH) of magnetically confined bacteria enables rapid determination of early-stage human bacteremia. Small Methods, 2022, 6(3), e2101239. doi: 10.1002/smtd.202101239
  313. Ast, J.; Novak, A.N.; Podewin, T.; Fine, N.H.F.; Jones, B.; Tomas, A.; Birke, R.; Roßmann, K.; Mathes, B:; Eichhorst, J.; Lehmann, M.; Linnemann, A.K.; Hodson, D.J.; Broichhagen, J. Expanded LUXendin color palette for GLP1R detection and visualization in vitro and in vivo. JACS Au, 2022, 2(4), 1007-1017. doi: 10.1021/jacsau.2c00130
  314. Futamata, H.; Fukuda, M.; Umeda, R.; Yamashita, K.; Takahashi, S.; Shikakura, Ta.; Hayashi, S.; Homma, K.; Nishizawa, T.; Nureki, O. Cryo-EM structures of thermostabilized prestin provide mechanistic insights underlying outer hair cell electromotility. Nature Communications, 2022, 13, 6208. doi: 10.1038/s41467-022-34017-x
  315. Cooley, M.B.; Abenojar, E.C.; Wegierak, D.; Gupta, A.S.; Kolios, M.C.; Exner, A.A. Characterization of the Interaction of Nanobubble Ultrasound Contrast Agents with Human Blood Components. Bioactive Materials, 2022, 19, 642-652. doi: 10.1016/j.bioactmat.2022.05.001
  316. Yagolovich, A.V.; Isakova, A.A.; Artykov, A.A.; Vorontsova, Y.V.; Mazur, D.V.; Antipova, N.V.; Pavlyukov, M.S.; Shakhparonov, M.I.; Gileva, A.M.; Markvicheva, E.A.; Plotnikova, E.A.; Pankratov, A.A.; Kirpichnikov, M.P.; Gasparian, M.E.; Dolgikh, D.A. DR5-Selective TRAIL Variant DR5-B Functionalized with Tumor-Penetrating iRGD Peptide for Enhanced Antitumor Activity against Glioblastoma. International Journal of Molecular Sciences, 2022, 23(20), 12687. doi: 10.3390/ijms232012687
  317. Gruenke, P.R.; Aneja, R.; Welbourn, S.; Ukah, O.B.; Sarafianos, S.G.; Burke, D.H.; Lange, M.J. Selection and identification of an RNA aptamer that specifically binds the HIV-1 capsid lattice and inhibits viral replication. Nucleic Acids Research, 2022, 50(3), 1701–1717. doi: 10.1093/nar/gkab1293
  318. Bellat, V.; Michel, A.O.; Thomas, C.; Stokol, T.; Choi, B.; Law, B. A urinary drug-disposing approach as an alternative to intravesical chemotherapy for treating non-muscle invasive bladder cancer. Cancer Research, 2022, 82(7), 1409–1422. doi: 10.1158/0008-5472.CAN-21-2897
  319. Yin, X.; Ren, J.; Lan, W.; Chen, Y.; Ouyang, M.; Su, H.; Zhang, L.; Zhu, J.; Zhang, C. Microfluidics-assisted optimization of highly adhesive haemostatic hydrogel coating for arterial puncture. Bioactive Materials, 2022, 12, 133-142. doi: 10.1016/j.bioactmat.2021.10.009
  320. Delvaux, N.A.; Mathew, B.; Rice, K.G. Fluorescent Labeling of Plasmid DNA for Gene Delivery: Implications of Dye Hydrophobicity on Labeling Efficiencies and Nanoparticle Size. Analytical Biochemistry, 2022, 644, 113895. doi: 10.1016/j.ab.2020.113895
  321. Kolyvanova, M.A.; Klimovich, M.A.; Shibaeva, A.V.; Koshevaya, E.D.; Bushmanov, Y.A.; Belousov, A.V.; Kuzmin, V.A.; Morozov, V.N. Cholesteric liquid-crystalline DNA – a new type of chemical detector of ionizing radiation. Liquid Crystals, 2022, 49(10). doi: 10.1080/02678292.2022.2032854
  322. Sun, F.; Wang, Y.; Wang, Q.; Wang, X.; Yao, P.; Feng, W.; Yuan, Q.; Qi, X.; Chen, S.; Pu, W.; Huang, R.; Dai, Q.; lv, J.; Wang, Q.; Shen, W.; Xia, P.; Zhang, D. Self-Illuminating Triggered Release of Therapeutics from Photocleavable Nanoprodrug for the Targeted Treatment of Breast Cancer. ACS Applied Materials & Interfaces, 2022, 14(7), 8766–8781. doi: 10.1021/acsami.1c21665
  323. Sokolov, A. V., Isakova-Sivak, I. N., Mezhenskaya, D. A., Kostevich, V. A., Gorbunov, N. P., Elizarova, A. Y., Matyushenko, V. A.; Berson, Y. M.; Grudinina, N. A.; Kolmakov, N. N.; Zabrodskaya, Y. A.; Komlev, A. S.; Semak, I. V.; Budevich, A. I.; Rudenko, L. G.; Vasilyev, V. B. Molecular mimicry of the receptor-binding domain of the SARS-CoV-2 spike protein: from the interaction of spike-specific antibodies with transferrin and lactoferrin to the antiviral effects of human recombinant lactoferrin. BioMetals, 2022. doi: 10.1007/s10534-022-00458-6
  324. Sokolov, A.; Isakova-Sivak, I.; Grudinina, N.; Mezhenskaya, D.; Litasova, E.; Kostevich, V.; Stepanova, E.; Rak, A.; Sychev, I.; Kirik, O.; & Rudenko, L. Ferristatin II Efficiently Inhibits SARS-CoV-2 Replication in Vero Cells. Viruses, 2022, 14(2), 317. doi: 10.3390/v14020317
  325. Rueda-Alaña, E.; García-Moreno, F. Time in Neurogenesis: Conservation of the Developmental Formation of the Cerebellar Circuitry. Brain, Behavior and Evolution, 2022, 97, 33-47. doi: 10.1159/000519068
  326. Diaz-Salmeron, R.; Toussaint, B.; Cailleau, C.; Ponchel, G.; Bouchemal, K. Morphology-Dependent Bioadhesion and Bioelimination of Hyaluronan Particles Administered in the Bladder. Advanced NanoBiomed Research, 2022, 2(5), 2100138. doi: 10.1002/anbr.202100138
  327. Maltsev, D.I.; Mellanson, K.A.; Belousov, V.V.; Enikolopov, G.N.; Podgorny, O.V. The bioavailability time of commonly used thymidine analogues after intraperitoneal delivery in mice: labeling kinetics in vivo and clearance from blood serum. Histochemistry and Cell Biology, 2022, 157, 239–250. doi: 10.1007/s00418-021-02048-y
  328. Ivanova, A.; Gruzova, O.; Ermolaeva, E.; Astakhova, O.; Itaman, S.; Enikolopov, G.; Lazutkin, A. Synthetic Thymidine Analog Labeling without Misconceptions. Cells, 2022, 11(12), 1888. doi: 10.3390/cells11121888
  329. Han, Z.; Chen, C.; Xu, X.; Bai, R.; Staedtke, V.; Huang, J.; Chan, K.W.Y.; Xu, J.; Kamson, D.O.; Wen, Z.; Knutsson, L.; Zijl, P.C.M.; Liu, G. Dynamic contrast-enhanced CEST MRI using a low molecular weight dextran. NMR in Biomedicine, 2022, 35(3), e4649. doi: 10.1002/nbm.4649
  330. Lee, J.; Kang, Y.K.; Oh, E.; Jeong, J.; Im, S.H.; Kim, D.K.; Lee, H.; Kim, S.-G.; Jung, K.; Chung, H.J. Nano-assembly of a Chemically Tailored Cas9 Ribonucleoprotein for In Vivo Gene Editing and Cancer Immunotherapy. Chemistry of Materials, 2022, 34(2), 547–561. doi: 10.1021/acs.chemmater.1c02844
  331. Vakhrushev, A.V.; Demin, A.M.; Krasnov, V.P. Synthesis of fluorescent GRGD peptide derivatives. AIP Conference Proceedings, 2022, 2390(1), 020083. doi: 10.1063/5.0069274
  332. Li, F.; Wei, Y.; Zhao, J.; Zhang, L.; Li, Q. In vivo pharmacokinetic study of a Cucurbita moschata polysaccharide after oral administration. International Journal of Biological Macromolecules, 2022, 203, 19–28. doi: 10.1016/j.ijbiomac.2022.01.111
  333. Kang, Y.; Nack, L.M.; Liu, Yang and.; Qi, B.; Huang, Y.; Liu, Z.; Chakraborty, I.; Schulz, F.; Ahmed, A.A.A.; Poveda, M.C.; Hafizi, F.; Roy, S.; Mutas, M.; Holzapfel, M.; Sanchez-Cano, C.; Wegner, K.D.; Feliu, N.; Parak, W.J. Quantitative considerations about the size dependence of cellular entry and excretion of colloidal nanoparticles for different cell types. ChemTexts, 2022, 8(1), 9. doi: 10.1007/s40828-021-00159-6
  334. Chung, I.J.; Moon, H.; Jeon, S.I.; Lee, H.J.; Ahn, C.-H. Ultrasound-triggered imaging and drug delivery using microbubble-self-aggregate complexes. Journal of Biomaterials Science, Polymer Edition, 2022, 33(1), 57–76. doi: 10.1080/09205063.2021.1976362
  335. Mamot, A.; Sikorski, P.J.; Siekierska, A.; de Witte, P.; Kowalska, J.; Jemielity, J. Ethylenediamine derivatives efficiently react with oxidized RNA 3′ ends providing access to mono and dually labelled RNA probes for enzymatic assays and in vivo translation. Nucleic Acids Research, 2022, 50(1), e3. doi: 10.1093/nar/gkab867
  336. Jobbins, A.M.; Campagne, S.; Weinmeister, R.; Lucas, C.M.; Gosliga, A.R.; Clery, A.; Chen, L.; Eperon, L.P.; Hodson, M.J.; Hudson, A.J.; Allain, F.H.T.; Eperon, I.C. Exon-independent recruitment of SRSF1 is mediated by U1 snRNP stem-loop 3. The EMBO Journal, 2022, 41(1), e107640. doi: 10.15252/embj.2021107640
  337. Kumar, A.; Singam, A.; Swaminathan, G.; Killi, N.; Tangudu, N.K.; Jose, J.; Rathna G.V.N.; Kumar, L.D. Combinatorial therapy using RNAi and curcumin nano-architectures regresses tumors in breast and colon cancer models. Nanoscale, 2022, 14(2), 492–505. doi: 10.1039/D1NR04411G
  338. Mohale, M.; Gundampati, R.K.; Thallapuranam, S.; Heyes, C.D. Site-specific labeling and functional efficiencies of human fibroblast growth Factor-1 with a range of fluorescent dyes in the flexible N-Terminal region and a rigid β-turn region. Analytical Biochemistry, 2022, 640, 114524. doi: 10.1016/j.ab.2021.114524
  339. Iacobazzi, R.M.; Arduino, I.; Di Fonte, R.; Lopedota, A.A.; Serratì, S.; Racaniello, G.; Bruno, V.; Laquintana, V.; Lee, B.-C.; Silvestris, N.; Leonetti, F.; Denora, N.; Porcelli, L.; Azzariti, A. Microfluidic-Assisted Preparation of Targeted pH-Responsive Polymeric Micelles Improves Gemcitabine Effectiveness in PDAC: In Vitro Insights. Cancers, 2022, 14(1), 5. doi: 10.3390/cancers14010005
  340. Guo, H.; Liu, L.; Hu, Q.; Dou, H. Monodisperse ZIF-8@dextran nanoparticles co-loaded with hydrophilic and hydrophobic functional cargos for combined near-infrared fluorescence imaging and photothermal therapy. Acta Biomaterialia, 2022, 137, 290–304. doi: 10.1016/j.actbio.2021.10.006
  341. Nekrasov, N.; Jaric, S.; Kireev, D.; Emelianov, A.V.; Orlov, A.V.; Gadjanski, I.; Nikitin, P.I.; Akinwande, D.; Bobrinetskiy, I. Real-time detection of ochratoxin A in wine through insight of aptamer conformation in conjunction with graphene field-effect transistяor. Biosensors and Bioelectronics, 2022, 200, 113890. doi: 10.1016/j.bios.2021.113890
  342. Mochalova, E. N.; Kotov, I. A.; Lifanov, D. A.; Chakraborti, S.; Nikitin, M. P. Imaging Flow Cytometry Data Analysis Using Convolutional Neural Network for Quantitative Investigation of Phagocytosis. Biotechnology and Bioengineering, 2022, 119(2), 626–635. doi: 10.1002/bit.27986
  343. Wachholz, V.; Mustafa, A.-H. M.; Zeyn, Y.; Henninger, S. J.; Beyer, M.; Dzulko, M.; Piée-Staffa, A.; Brachetti, C.; Haehnel, P. S.; Sellmer, A.; Mahboobi, S.; Kindler, T.; Brenner, W.; Nikolova, T.; Krämer, O. H. Inhibitors of Class I HDACs and of FLT3 Combine Synergistically against Leukemia Cells with Mutant FLT3. Arch Toxicol, 2022, 96(1), 177–193. doi: 10.1007/s00204-021-03174-1
  344. Wang, Y.; Song, X.; Zhuang, L.; Lang, H.; Yu, L.; Yan, X.; He, Z. Kinetic Control of Phytic Acid/Lixisenatide/Fe (III) Ternary Nanoparticles Assembly Process for Sustained Peptide Release. International Journal of Pharmaceutics, 2022, 611, 121317. doi: 10.1016/j.ijpharm.2021.121317
  345. Tully, M.; Hauptstein, N.; Licha, K.; Meinel, L.; Lühmann, T.; Haag, R. Linear Polyglycerol for N-Terminal-Selective Modification of Interleukin-4. Journal of Pharmaceutical Sciences, 2022, 111(6), 1642–1651. doi: 10.1016/j.xphs.2021.10.032
  346. Lim, S.; An, S. B.; Jung, M.; Joshi, H. P.; Kumar, H.; Kim, C.; Song, S. Y.; Lee, J.-R.; Kang, M.; Han, I.; Kim, B.-S. Local Delivery of Senolytic Drug Inhibits Intervertebral Disc Degeneration and Restores Intervertebral Disc Structure. Advanced Healthcare Materials, 2022, 11(2), 2101483. doi: 10.1002/adhm.202101483
  347. Lim, S.; An, S. B.; Jung, M.; Joshi, H. P.; Kumar, H.; Kim, C.; Song, S. Y.; Lee, J.-R.; Kang, M.; Han, I.; Kim, B.-S. Local Delivery of Senolytic Drug Inhibits Intervertebral Disc Degeneration and Restores Intervertebral Disc Structure. Advanced Healthcare Materials, 2022, 11(2), 2101483. doi: 10.1002/adhm.202101483
  348. Geng, Y.; Xiang, J.; Shao, S.; Tang, J.; Shen, Y. Mitochondria-Targeted Polymer-Celastrol Conjugate with Enhanced Anticancer Efficacy. Journal of Controlled Release, 2022, 342, 122–133. doi: 10.1016/j.jconrel.2022.01.002
  349. Giudice, C. L.; Yang, J.; Poncin, M. A.; Adumeau, L.; Delguste, M.; Koehler, M.; Evers, K.; Dumitru, A. C.; Dawson, K. A.; Alsteens, D. Nanophysical Mapping of Inflammasome Activation by Nanoparticles via Specific Cell Surface Recognition Events. ACS Nano, 2022, 16(1), 306–316. doi: 10.1021/acsnano.1c06301
  350. An, S.; Nam, J.; Kanimozhi, C.; Song, Y.; Kim, S.; Shin, N.; Gopalan, P.; Kim, M. Photoimageable Organic Coating Bearing Cyclic Dithiocarbonate for a Multifunctional Surface. ACS Appl. Mater. Interfaces, 2022, 14(2), 3274–3283. doi: 10.1021/acsami.1c19559
  351. Zhou, H.; Chen, P.; Dai, F.; Wang, J. Up-Regulation of TGFBI and TGFB2 in the Plasma of Gestational Diabetes Mellitus Patients and Its Clinical Significance. Ir J Med Sci, 2022, 191(5), 2029–2033. doi: 10.1007/s11845-021-02838-2
  352. Nekrasov, N.; Jaric, S.; Kireev, D.; Emelianov, A. V.; Orlov, A. V.; Gadjanski, I.; Nikitin, P. I.; Akinwande, D.; Bobrinetskiy, I. Real-Time Detection of Ochratoxin A in Wine through Insight of Aptamer Conformation in Conjunction with Graphene Field-Effect Transistor. Biosensors and Bioelectronics, 2022, 200, 113890. doi: 10.1016/j.bios.2021.113890
  353. Muraru, S.; Muraru, S.; Nitu, F. R.; Ionita, M. Recent Efforts and Milestones for Simulating Nucleic Acid FRET Experiments through Computational Methods. J. Chem. Inf. Model., 2022, 62(1), 232–239. doi: 10.1021/acs.jcim.1c00957
  354. Jahn, K.; Kurz, B.; Sinke, C.; Kneer, J.; Riemer, O.; Ponseti, J.; Walter, M.; Beier, K. M.; Walter, H.; Frieling, H.; Schiffer, B.; Kruger, T. H. C. Serotonin System-Associated Genetic and Epigenetic Changes in Pedophilia and Child Sexual Offending. Journal of Psychiatric Research, 2022, 145, 60–69. doi: 10.1016/j.jpsychires.2021.11.042
  355. Francis, C.; Wroblewska, L.; Pegman, P.; Amiji, M. Systemic Biodistribution and Hepatocyte-Specific Gene Editing with CRISPR/Cas9 Using Hyaluronic Acid-Based Nanoparticles. Nanomedicine: Nanotechnology, Biology and Medicine, 2022, 40, 102488. doi: 10.1016/j.nano.2021.102488

2021

  1. Feng, H.-Y.; Yuan, Y.; Zhang, Y.; Liu, H.-J.; Dong, X.; Yang, S.-C.; Liu, X.-L.; Lai, X.; Zhu, M.-H.; Wang, J.; Lu, Q.; Lin, Q.; Chen, H.-Z.; Lovell, J. F.; Sun, P.; Fang, C. Targeted Micellar Phthalocyanine for Lymph Node Metastasis Homing and Photothermal Therapy in an Orthotopic Colorectal Tumor Model. Nano-Micro Lett., 2021, 13(1), 145. doi: 10.1007/s40820-021-00666-8
  2. Song, Z.; Gremminger, T.; Singh, G.; Cheng, Y.; Li, J.; Qiu, L.; Ji, J.; Lange, M. J.; Zuo, X.; Chen, S.-J.; Zou, X.; Boris-Lawrie, K.; Heng, X. The Three-Way Junction Structure of the HIV-1 PBS-Segment Binds Host Enzyme Important for Viral Infectivity. Nucleic Acids Research, 2021, 49(10), 5925–5942. doi: 10.1093/nar/gkab342
  3. Zharinov, G. M.; Khalchitsky, S. E.; Loktionov, A.; Sogoyan, M. V.; Khutoryanskaya, Y. V.; Neklasova, N. Y.; Bogomolov, O. A.; Smirnov, I. V.; Samoilovich, M. P.; Skakun, V. N.; Vissarionov, S. V.; Anisimov, V. N. The Presence of Polymorphisms in Genes Controlling Neurotransmitter Metabolism and Disease Prognosis in Patients with Prostate Cancer: A Possible Link with Schizophrenia. Oncotarget, 2021, 12(7), 698–707. doi: 10.18632/oncotarget.27921
  4. Kim, K. R.; You, S. J.; Kim, H. J.; Yang, D. H.; Chun, H. J.; Lee, D.; Khang, G. Theranostic Potential of Biodegradable Polymeric Nanoparticles with Paclitaxel and Curcumin against Breast Carcinoma. Biomater. Sci., 2021, 9(10), 3750–3761. doi: 10.1039/D1BM00370D
  5. Li, R.; Ng, T. S. C.; Wang, S. J.; Prytyskach, M.; Rodell, C. B.; Mikula, H.; Kohler, R. H.; Garlin, M. A.; Lauffenburger, D. A.; Parangi, S.; Dinulescu, D. M.; Bardeesy, N.; Weissleder, R.; Miller, M. A. Therapeutically Reprogrammed Nutrient Signalling Enhances Nanoparticulate Albumin Bound Drug Uptake and Efficacy in KRAS-Mutant Cancer. Nat. Nanotechnol., 2021, 16(7), 830–839. doi: 10.1038/s41565-021-00897-1
  6. Garry, G. A.; Bezprozvannaya, S.; Chen, K.; Zhou, H.; Hashimoto, H.; Morales, M. G.; Liu, N.; Bassel-Duby, R.; Olson, E. N. The Histone Reader PHF7 Cooperates with the SWI/SNF Complex at Cardiac Super Enhancers to Promote Direct Reprogramming. Nat Cell Biol, 2021, 23(5), 467–475. doi: 10.1038/s41556-021-00668-z
  7. Zhang, T.; Fu, C.; Alradwan, I.; Yen, T.; Lip, H.; Cai, P.; Rauth, A. M.; Zhang, L.; Wu, X. Y. Targeting Signaling Pathways of Hyaluronic Acid and Integrin Receptors by Synergistic Combination Nanocomposites Inhibits Systemic Metastases and Primary Triple Negative Breast Cancer. Advanced Therapeutics, 2021, 4(6), 2100022. doi: 10.1002/adtp.202100022
  8. Biswas, S.; Wu, C.; van der Donk, W. A. The Antimicrobial Activity of the Glycocin Sublancin Is Dependent on an Active Phosphoenolpyruvate-Sugar Phosphotransferase System. ACS Infect. Dis., 2021, 7(8), 2402–2412. doi: 10.1021/acsinfecdis.1c00157
  9. Babi, M.; Riesco, R.; Boyer, L.; Fatona, A.; Accardo, A.; Malaquin, L.; Moran-Mirabal, J. Tuning the Nanotopography and Chemical Functionality of 3D Printed Scaffolds through Cellulose Nanocrystal Coatings. ACS Appl. Bio Mater., 2021, 4(12), 8443–8455. doi: 10.1021/acsabm.1c00970
  10. Kupryushkin, M. S.; Zharkov, T. D.; Ilina, E. S.; Markov, O. V.; Kochetkova, A. S.; Akhmetova, M. M.; Lomzov, A. A.; Pyshnyi, D. V.; Lavrik, O. I.; Khodyreva, S. N. Triazinylamidophosphate Oligonucleotides: Synthesis and Study of Their Interaction with Cells and DNA-Binding Proteins. Russ J Bioorg Chem, 2021, 47(3), 719–733. doi: 10.1134/S1068162021030110
  11. Shukla, S.; Marks, I.; Church, D.; Chan, S.-K.; K. Pokorski, J.; F. Steinmetz, N. Tobacco Mosaic Virus for the Targeted Delivery of Drugs to Cells Expressing Prostate-Specific Membrane Antigen. RSC Advances, 2021, 11(33), 20101–20108. doi: 10.1039/D1RA03166J
  12. Ha, L.; Choi, K. M.; Kim, D.-P. Interwoven MOF-Coated Janus Cells as a Novel Carrier of Toxic Proteins. ACS Appl. Mater. Interfaces, 2021, 13(16), 18545–18553. doi: 10.1021/acsami.1c01927
  13. Leiske, M. N.; Lai, M.; Amarasena, T.; Davis, T. P.; Thurecht, K. J.; Kent, S. J.; Kempe, K. Biomaterials. Interactions of Core Cross-Linked Poly(2-Oxazoline) and Poly(2-Oxazine) Micelles with Immune Cells in Human Blood, 2021, 274, 120843. doi: 10.1016/j.biomaterials.2021.120843
  14. Mu, W.; Li, S.; Xu, J.; Guo, X.; Wu, H.; Chen, Z.; Qiao, L.; Helfer, G.; Lu, F.; Liu, C.; Wu, Q.-F. Hypothalamic Rax+ Tanycytes Contribute to Tissue Repair and Tumorigenesis upon Oncogene Activation in Mice. Nat Commun, 2021, 12(1), 2288. doi: 10.1038/s41467-021-22640-z
  15. Lee, F.; Hyun Bae, K.; Ng, S.; Yamashita, A.; Kurisawa, M. Hyaluronic Acid–Green Tea Catechin Conjugates as a Potential Therapeutic Agent for Rheumatoid Arthritis. RSC Advances, 2021, 11(24), 14285–14294. doi: 10.1039/D1RA01491A
  16. Parayath, N. N.; Hong, B. V.; Mackenzie, G. G.; Amiji, M. M. Hyaluronic Acid Nanoparticle-Encapsulated MicroRNA-125b Repolarizes Tumor-Associated Macrophages in Pancreatic Cancer. Nanomedicine, 2021, 16(25), 2291–2303. doi: 10.2217/nnm-2021-0080
  17. Le, T.-N.; Lin, C.-J.; Shen, Y. C.; Lin, K.-Y.; Lee, C.-K.; Huang, C.-C.; Rao, N. V. Hyaluronic Acid Derived Hypoxia-Sensitive Nanocarrier for Tumor Targeted Drug Delivery. ACS Appl. Bio Mater., 2021, 4(12), 8325–8332. doi: 10.1021/acsabm.1c00847
  18. Rhodes, J. W.; Botting, R. A.; Bertram, K. M.; Vine, E. E.; Rana, H.; Baharlou, H.; Vegh, P.; O’Neil, T. R.; Ashhurst, A. S.; Fletcher, J.; Parnell, G. P.; Graham, J. D.; Nasr, N.; Lim, J. J. K.; Barnouti, L.; Haertsch, P.; Gosselink, M. P.; Di Re, A.; Reza, F.; Ctercteko, G.; Jenkins, G. J.; Brooks, A. J.; Patrick, E.; Byrne, S. N.; Hunter, E.; Haniffa, M. A.; Cunningham, A. L.; Harman, A. N. Human Anogenital Monocyte-Derived Dendritic Cells and Langerin+cDC2 Are Major HIV Target Cells. Nat Commun, 2021, 12(1), 2147. doi: 10.1038/s41467-021-22375-x
  19. Noskov, R.; Machnev, A.; Shishkin, I.; Novoselova, M.; Gaier, A.; Ezhov, A.; Shirshin, E.; German, S. V.; Rukhlenko, I.; Fleming, S.; Khlebtsov, B.; Gorin, D.; Ginzburg, P. Golden Vaterite as a Mesoscopic Metamaterial for Biophotonic Applications. Advanced Materials, 2021, 2008484. doi: 10.1002/adma.202008484
  20. Khawaja, R. R.; Agarwal, A.; Fukaya, M.; Jeong, H.-K.; Gross, S.; Gonzalez-Fernandez, E.; Soboloff, J.; Bergles, D. E.; Kang, S. H. GluA2 Overexpression in Oligodendrocyte Progenitors Promotes Postinjury Oligodendrocyte Regeneration. Cell Reports, 2021, 35(7), 109147. doi: 10.1016/j.celrep.2021.109147
  21. Hsu, C.-F.; Chang, K.-C.; Chen, Y.-L.; Hsieh, P.-S.; Lee, A.-I.; Tu, J.-Y.; Chen, Y.-T.; Wen, J.-D. Formation of Frameshift-Stimulating RNA Pseudoknots Is Facilitated by Remodeling of Their Folding Intermediates. Nucleic Acids Research, 2021, 49(12), 6941–6957. doi: 10.1093/nar/gkab512
  22. Zhang, S.; Li, G.; Deng, D.; Dai, Y.; Liu, Z.; Wu, S. Fluorinated Chitosan Mediated Synthesis of Copper Selenide Nanoparticles with Enhanced Penetration for Second Near-Infrared Photothermal Therapy of Bladder Cancer. Advanced Therapeutics, 2021, 4(7), 2100043. doi: 10.1002/adtp.202100043
  23. Bou, S.; Klymchenko, A. S.; Collot, M. Fluorescent Labeling of Biocompatible Block Copolymers: Synthetic Strategies and Applications in Bioimaging. Mater. Adv., 2021, 2(10), 3213–3233. doi: 10.1039/D1MA00110H
  24. Lin, J.-C.; Hsu, C.-Y.; Chen, J.-Y.; Fang, Z.-S.; Chen, H.-W.; Yao, B.-Y.; Shiau, G. H. M.; Tsai, J.-S.; Gu, M.; Jung, M.; Lee, T.-Y.; Hu, C.-M. J. Facile Transformation of Murine and Human Primary Dendritic Cells into Robust and Modular Artificial Antigen-Presenting Systems by Intracellular Hydrogelation. Advanced Materials, 2021, 33(30), 2101190. doi: 10.1002/adma.202101190
  25. Kim, C.; Shon, M. J.; Kim, S. H.; Eun, G. S.; Ryu, J.-K.; Hyeon, C.; Jahn, R.; Yoon, T.-Y. Extreme Parsimony in ATP Consumption by 20S Complexes in the Global Disassembly of Single SNARE Complexes. Nat Commun, 2021, 12(1), 3206. doi: 10.1038/s41467-021-23530-0
  26. Zhang, E.; Osipova, N.; Sokolov, M.; Maksimenko, O.; Semyonkin, A.; Wang, M.; Grigartzik, L.; Gelperina, S.; Sabel, B. A.; Henrich-Noack, P. Exploring the Systemic Delivery of a Poorly Water-Soluble Model Drug to the Retina Using PLGA Nanoparticles. European Journal of Pharmaceutical Sciences, 2021, 164, 105905. doi: 10.1016/j.ejps.2021.105905
  27. Hu, K.-W.; Fan, H.-F.; Lin, H.-C.; Huang, J.-W.; Chen, Y.-C.; Shen, C.-L.; Shih, Y.-H.; Tu, L.-H. Exploring the Impact of Glyoxal Glycation on β-Amyloid Peptide (Aβ) Aggregation in Alzheimer’s Disease. J. Phys. Chem. B, 2021, 125(21), 5559–5571. doi: 10.1021/acs.jpcb.1c02797
  28. Clark, H. R.; McKenney, C.; Livingston, N. M.; Gershman, A.; Sajjan, S.; Chan, I. S.; Ewald, A. J.; Timp, W.; Wu, B.; Singh, A.; Regot, S. Epigenetically Regulated Digital Signaling Defines Epithelial Innate Immunity at the Tissue Level. Nat Commun, 2021, 12(1), 1836. doi: 10.1038/s41467-021-22070-x
  29. Damavandi, F.; Wang, W.; Shen, W.-Z.; Cetinel, S.; Jordan, T.; Jovel, J.; Montemagno, C.; Wong, G. K.-S. Enrichment of Low Abundance DNA/RNA by Oligonucleotide-Clicked Iron Oxide Nanoparticles. Sci Rep, 2021, 11(1), 13053. doi: 10.1038/s41598-021-92376-9
  30. Jäger, E.; Humajová, J.; Dölen, Y.; Kučka, J.; Jäger, A.; Konefał, R.; Pankrác, J.; Pavlova, E.; Heizer, T.; Šefc, L.; Hrubý, M.; Figdor, C. G.; Verdoes, M. Enhanced Antitumor Efficacy through an “AND Gate” Reactive Oxygen-Species-Dependent PH-Responsive Nanomedicine Approach. Advanced Healthcare Materials, 2021, 10(13), 2100304. doi: 10.1002/adhm.202100304
  31. Pan, H.; Li, L.; Pang, G.; Han, C.; Liu, B.; Zhang, Y.; Shen, Y.; Sun, T.; Liu, J.; Chang, J.; Wang, H. Engineered NIR Light-Responsive Bacteria as Anti-Tumor Agent for Targeted and Precise Cancer Therapy. Chemical Engineering Journal, 2021, 426, 130842. doi: 10.1016/j.cej.2021.130842
  32. Yin, S.; Wang, Y.; Zhang, B.; Qu, Y.; Liu, Y.; Dai, S.; Zhang, Y.; Wang, Y.; Bi, J. Engineered Human Heavy-Chain Ferritin with Half-Life Extension and Tumor Targeting by PAS and RGDK Peptide Functionalization. Pharmaceutics, 2021, 13(4), 521. doi: 10.3390/pharmaceutics13040521
  33. Yan, Y.; Hernandez-Andrade, E.; Basij, M.; Alshahrani, S. S.; Kondle, S.; Brown, B. O.; Gelovani, J.; Hassan, S.; Hsu, C.-D.; Mehrmohammadi, M. Endocavity Ultrasound and Photoacoustic System for Fetal and Maternal Imaging: Design, Implementation, and Ex-Vivo Validation. JMI, 2021, 8(6), 066001. doi: 10.1117/1.JMI.8.6.066001
  34. Peplau, E.; De Rose, F.; Eichinger, A.; Reder, S.; Mittelhäuser, M.; Scafetta, G.; Schwaiger, M.; Weber, W. A.; Bartolazzi, A.; D’Alessandria, C.; Skerra, A. Effective Rational Humanization of a PASylated Anti-Galectin-3 Fab for the Sensitive PET Imaging of Thyroid Cancer in Vivo. Sci Rep, 2021, 11(1), 7358. doi: 10.1038/s41598-021-86641-0
  35. Min, K.; Yoo, S.; Han, M. S.; Tae, G. Effective and Prolonged Targeting of a Nanocarrier to the Inflammation Site by Functionalization with ZnBPMP and Chitosan. Materials Science and Engineering: C, 2021, 131, 112521. doi: 10.1016/j.msec.2021.112521
  36. Epanchintseva, A. V.; Gorbunova, E. A.; Ryabchikova, E. I.; Pyshnaya, I. A.; Pyshnyi, D. V. Effect of Fluorescent Labels on DNA Affinity for Gold Nanoparticles. Nanomaterials, 2021, 11(5), 1178. doi: 10.3390/nano11051178
  37. Ouali, R.; Vieira, L. R.; Salmon, D.; Bousbata, S. Early Post-Prandial Regulation of Protein Expression in the Midgut of Chagas Disease Vector Rhodnius Prolixus Highlights New Potential Targets for Vector Control Strategy. Microorganisms, 2021, 9(4), 804. doi: 10.3390/microorganisms9040804
  38. Lunn, A. M.; Unnikrishnan, M.; Perrier, S. Dual PH-Responsive Macrophage-Targeted Isoniazid Glycoparticles for Intracellular Tuberculosis Therapy. Biomacromolecules, 2021, 22(9), 3756–3768. doi: 10.1021/acs.biomac.1c00554
  39. Li, H.; Wang, Z.; Chen, Z.; Ci, T.; Chen, G.; Wen, D.; Li, R.; Wang, J.; Meng, H.; Bryan Bell, R.; Gu, Z.; Dotti, G.; Gu, Z. Disrupting Tumour Vasculature and Recruitment of APDL1-Loaded Platelets Control Tumour Metastasis. Nat Commun, 2021, 12(1), 2773. doi: 10.1038/s41467-021-22674-3
  40. Schmitner, N.; Recheis, C.; Thönig, J.; Kimmel, R. A. Differential Responses of Neural Retina Progenitor Populations to Chronic Hyperglycemia. Cells, 2021, 10(11), 3265. doi: 10.3390/cells10113265
  41. Donlin-Asp, P. G.; Polisseni, C.; Klimek, R.; Heckel, A.; Schuman, E. M. Differential Regulation of Local MRNA Dynamics and Translation Following Long-Term Potentiation and Depression. Proc Natl Acad Sci U S A, 2021, 118(13), e2017578118. doi: 10.1073/pnas.2017578118
  42. Trinh, P. N. H.; Chong, D. J. W.; Leach, K.; Hill, S. J.; Tyndall, J. D. A.; May, L. T.; Vernall, A. J.; Gregory, K. J. Development of Covalent, Clickable Probes for Adenosine A1 and A3 Receptors. J. Med. Chem., 2021, 64(12), 8161–8178. doi: 10.1021/acs.jmedchem.0c02169
  43. Wang, Y.; Li, Y.; Cao, J.; Meng, Q.; Li, X.; Zhang, Y.; Lam, K. S.; Hong, A.; Liu, R.; Chen, X. Development and Characterization of a Novel Peptide—Drug Conjugate with DM1 for Treatment of FGFR2-Positive Tumors. Biomedicines, 2021, 9(8), 849. doi: 10.3390/biomedicines9080849
  44. Sapozhnikova, K. A.; Misyurin, A. V.; Pestov, N. B.; Meleshkina, E. G.; Oreshkov, S. D.; Ganzhula, E. P.; Mikhailova, A. S.; Korshun, V. A.; Misyurin, V. A.; Brylev, V. A. Detection of the PRAME Protein on the Surface of Melanoma Cells Using a Fluorescently Labeled Monoclonal Antibody. Russ J Bioorg Chem, 2021, 47(5), 1077–1085. doi: 10.1134/S1068162021050332
  45. Park, J.; Wen, A. M.; Gao, H.; Shin, M. D.; Simon, D. I.; Wang, Y.; Steinmetz, N. F. Designing S100A9-Targeted Plant Virus Nanoparticles to Target Deep Vein Thrombosis. Biomacromolecules, 2021, 22(6), 2582–2594. doi: 10.1021/acs.biomac.1c00303
  46. Kim, S.-Y.; Han, G.; Hwang, D.-B.; Won, D.-H.; Shin, Y.-S.; Kim, C.; Kang, J. M.; Park, J.-H.; Jung, H.-D.; Park, W.; Yun, J.-W. Design and Usability Evaluations of a 3D-Printed Implantable Drug Delivery Device for Acute Liver Failure in Preclinical Settings. Advanced Healthcare Materials, 2021, 10(14), 2100497. doi: 10.1002/adhm.202100497
  47. Richard, E. T.; Morinaga, K.; Zheng, Y.; Sundberg, O.; Hokugo, A.; Hui, K.; Zhou, Y.; Sasaki, H.; Kashemirov, B. A.; Nishimura, I.; McKenna, C. E. Design and Synthesis of Cathepsin-K-Activated Osteoadsorptive Fluorogenic Sentinel (OFS) Probes for Detecting Early Osteoclastic Bone Resorption in a Multiple Myeloma Mouse Model. Bioconjugate Chem., 2021, 32(5), 916–927. doi: 10.1021/acs.bioconjchem.1c00036
  48. Chetverikov, P. E.; Fedorov, D. S.; Letukhova, V. Y.; Romanovich, A. E. Description of Cecidophyes Fibigiae n. Sp., New Combinations, Records, and DNA Barcodes of Eriophyid Mites (Eriophyoidea, Eriophyidae) from Karadag Nature Reserve (Crimea). Systematic and Applied Acarology, 2021, 26(4), 818-828. doi: 10.11158/saa.26.4.12
  49. Park, J. Y.; You, S. J.; Park, K.; Song, Y. J.; Park, J. S.; Yang, D. H.; Kim, J. K.; Chun, H. J.; Khang, G. Cyclic RGDfK- and Sulfo-Cy5.5-Functionalized MPEG-PCL Theranostic Nanosystems for Hepatocellular Carcinoma. Journal of Industrial and Engineering Chemistry, 2021, 99, 204–213. doi: 10.1016/j.jiec.2021.04.023
  50. Ortega-Rivera, O. A.; Shukla, S.; Shin, M. D.; Chen, A.; Beiss, V.; Moreno-Gonzalez, M. A.; Zheng, Y.; Clark, A. E.; Carlin, A. F.; Pokorski, J. K.; Steinmetz, N. F. Cowpea Mosaic Virus Nanoparticle Vaccine Candidates Displaying Peptide Epitopes Can Neutralize the Severe Acute Respiratory Syndrome Coronavirus. ACS Infect. Dis., 2021, 7(11), 3096–3110. doi: 10.1021/acsinfecdis.1c00410
  51. Bartlett, C.; Langsjoen, J.; Cheng, Q.; Yingling, A. V.; Weiss, M.; Bradfute, S.; Perkins, D. J.; Hurwitz, I. COVID-19 Global Pandemic Planning: Presence of SARS-CoV-2 Fomites in a University Hospital Setting. Exp Biol Med (Maywood), 2021, 246(18), 2039–2045. doi: 10.1177/15353702211024597
  52. Choi, S.; Zhang, B.; Ma, S.; Gonzalez-Celeiro, M.; Stein, D.; Jin, X.; Kim, S. T.; Kang, Y.-L.; Besnard, A.; Rezza, A.; Grisanti, L.; Buenrostro, J. D.; Rendl, M.; Nahrendorf, M.; Sahay, A.; Hsu, Y.-C. Corticosterone Inhibits GAS6 to Govern Hair Follicle Stem-Cell Quiescence. Nature, 2021, 592(7854), 428–432. doi: 10.1038/s41586-021-03417-2
  53. Bauer, T. A.; Horvat, N. K.; Marques, O.; Chocarro, S.; Mertens, C.; Colucci, S.; Schmitt, S.; Carrella, L. M.; Morsbach, S.; Koynov, K.; Fenaroli, F.; Blümler, P.; Jung, M.; Sotillo, R.; Hentze, M. W.; Muckenthaler, M. U.; Barz, M. Core Cross-Linked Polymeric Micelles for Specific Iron Delivery: Inducing Sterile Inflammation in Macrophages. Advanced Healthcare Materials, 2021, 10(19), 2100385. doi: 10.1002/adhm.202100385
  54. Scott, A. J.; Niitsu, A.; Kratochvil, H. T.; Lang, E. J. M.; Sengel, J. T.; Dawson, W. M.; Mahendran, K. R.; Mravic, M.; Thomson, A. R.; Brady, R. L.; Liu, L.; Mulholland, A. J.; Bayley, H.; DeGrado, W. F.; Wallace, M. I.; Woolfson, D. N. Constructing Ion Channels from Water-Soluble α-Helical Barrels. Nat. Chem., 2021, 13(7), 643–650. doi: 10.1038/s41557-021-00688-0
  55. Guan, J.; You, S.; Xiang, Y.; Schimelman, J.; Alido, J.; Ma, X.; Tang, M.; Chen, S. Compensating the Cell-Induced Light Scattering Effect in Light-Based Bioprinting Using Deep Learning. Biofabrication, 2021, 14(1), 015011. doi: 10.1088/1758-5090/ac3b92
  56. Borvinskaya, E.; Kochneva, A.; Bedulina, D.; Sukhovskaya, I.; Smirnov, L.; Babkina, I. Comparative Analysis of Proteins of Functionally Different Body Parts of the Fish Parasites Triaenophorus Nodulosus and Triaenophorus Crassus. Acta Parasit., 2021, 66(4), 1137–1150. doi: 10.1007/s11686-021-00384-6
  57. Kotova, A. V.; Lobov, A. A.; Dombrovskaya, J. A.; Sannikova, V. Y.; Ryumina, N. A.; Klausen, P.; Shavarda, A. L.; Malashicheva, A. B.; Enukashvily, N. I. Comparative Analysis of Dental Pulp and Periodontal Stem Cells: Differences in Morphology, Functionality, Osteogenic Differentiation and Proteome. Biomedicines, 2021, 9(11), 1606. doi: 10.3390/biomedicines9111606
  58. Co, C. M.; Izuagbe, S.; Zhou, J.; Zhou, N.; Sun, X.; Borrelli, J.; Tang, L. Click Chemistry-Based Pre-Targeting Cell Delivery for Cartilage Regeneration. Regenerative Biomaterials, 2021, 8(3), rbab018. doi: 10.1093/rb/rbab018
  59. Ji, D.; Lyu, K.; Zhao, H.; Kwok, C. K. Circular L-RNA Aptamer Promotes Target Recognition and Controls Gene Activity. Nucleic Acids Research, 2021, 49(13), 7280–7291. doi: 10.1093/nar/gkab593
  60. Merta, H.; Carrasquillo Rodríguez, J. W.; Anjur-Dietrich, M. I.; Vitale, T.; Granade, M. E.; Harris, T. E.; Needleman, D. J.; Bahmanyar, S. Cell Cycle Regulation of ER Membrane Biogenesis Protects against Chromosome Missegregation. Developmental Cell, 2021, 56(24), 3364-3379.e10. doi: 10.1016/j.devcel.2021.11.009
  61. Yang, H. Y.; Meng Du, J.; Jang, M.-S.; Mo, X. W.; Sun, X. S.; Lee, D. S.; Lee, J. H.; Fu, Y. CD44-Targeted and Enzyme-Responsive Photo-Cross-Linked Nanogels with Enhanced Stability for In Vivo Protein Delivery. Biomacromolecules, 2021, 22(8), 3590–3600. doi: 10.1021/acs.biomac.1c00653
  62. Kang, Y. K.; Lee, J.; Im, S. H.; Lee, J. H.; Jeong, J.; Kim, D. K.; Yang, S. Y.; Jung, K.; Kim, S.-G.; Chung, H. J. Cas9 Conjugate Complex Delivering Donor DNA for Efficient Gene Editing by Homology-Directed Repair. Journal of Industrial and Engineering Chemistry, 2021, 102, 241–250. doi: 10.1016/j.jiec.2021.07.009
  63. Hoque, J.; Shih, Y.-R. V.; Zeng, Y.; Newman, H.; Sangaj, N.; Arjunji, N.; Varghese, S. Bone Targeting Nanocarrier-Assisted Delivery of Adenosine to Combat Osteoporotic Bone Loss. Biomaterials, 2021, 273, 120819. doi: 10.1016/j.biomaterials.2021.120819
  64. Das, A.; Vishvakarma, V.; Dey, A.; Dey, S.; Gupta, A.; Das, M.; Vishwakarma, K. K.; Roy, D. S.; Yadav, S.; Kesarwani, S.; Venkatramani, R.; Maiti, S. Biophysical Properties of the Isolated Spike Protein Binding Helix of Human ACE2. Biophysical Journal, 2021, 120(14), 2785–2792. doi: 10.1016/j.bpj.2021.06.017
  65. Shin, M. D.; Hochberg, J. D.; Pokorski, J. K.; Steinmetz, N. F. Bioconjugation of Active Ingredients to Plant Viral Nanoparticles Is Enhanced by Preincubation with a Pluronic F127 Polymer Scaffold. ACS Appl. Mater. Interfaces, 2021, 13(50), 59618–59632. doi: 10.1021/acsami.1c13183
  66. Erokhina, T. N.; Ryazantsev, D. Yu.; Samokhvalova, L. V.; Mozhaev, A. A.; Orsa, A. N.; Zavriev, S. K.; Morozov, S. Yu. Activity of Chemically Synthesized Peptide Encoded by the MiR156A Precursor and Conserved in the Brassicaceae Family Plants. Biochemistry Moscow, 2021, 86(5), 551–562. doi: 10.1134/S0006297921050047
  67. Shramova, E. I.; Shilova, M. V.; Ryabova, A. V.; Dzhalilova, D. S.; Zolotova, N. A.; Telegin, G. B.; Deyev, S. M.; Proshkina, G. M. Barnase*Barstar-Guided Two-Step Targeting Approach for Drug Delivery to Tumor Cells in Vivo. Journal of Controlled Release, 2021, 340, 200–208. doi: 10.1016/j.jconrel.2021.11.001
  68. Goujon, G.; Baldim, V.; Roques, C.; Bia, N.; Seguin, J.; Palmier, B.; Graillot, A.; Loubat, C.; Mignet, N.; Margaill, I.; Berret, J.-F.; Beray-Berthat, V. Antioxidant Activity and Toxicity Study of Cerium Oxide Nanoparticles Stabilized with Innovative Functional Copolymers. Adv Healthcare Materials, 2021, 10(11), 2100059. doi: 10.1002/adhm.202100059
  69. Chen, K.; Si, Y.; Ou, J.; Guan, J.-S.; Kim, S.; Ernst, P.; Zhang, Y.; Zhou, L.; Han, X.; Liu, X. Antibody–Drug Conjugate to Treat Meningiomas. Pharmaceuticals, 2021, 14(5), 427. doi: 10.3390/ph14050427
  70. Si, Y.; Zhang, Y.; Guan, J.-S.; Ngo, H. G.; Totoro, A.; Singh, A. P.; Chen, K.; Xu, Y.; Yang, E. S.; Zhou, L.; Liu, R.; Liu, X. Anti-CD47 Monoclonal Antibody–Drug Conjugate: A Targeted Therapy to Treat Triple-Negative Breast Cancers. Vaccines, 2021, 9(8), 882. doi: 10.3390/vaccines9080882.
  71. Sun, Y. J.; Lin, C.-H.; Wu, M.-R.; Lee, S. H.; Yang, J.; Kunchur, C. R.; Mujica, E. M.; Chiang, B.; Jung, Y. S.; Wang, S.; Mahajan, V. B. An Intravitreal Implant Injection Method for Sustained Drug Delivery into Mouse Eyes. Cell Reports Methods, 2021, 1(8), 100125. doi: 10.1016/j.crmeth.2021.100125
  72. Chen, R.; Zhu, C.; Xu, L.; Gu, Y.; Ren, S.; Bai, H.; Zhou, Q.; Liu, X.; Lu, S.; Bi, X.; Li, W.; Jia, X.; Chen, Z. An Injectable Peptide Hydrogel with Excellent Self-Healing Ability to Continuously Release Salvianolic Acid B for Myocardial Infarction. Biomaterials, 2021, 274, 120855. doi: 10.1016/j.biomaterials.2021.120855
  73. Klein, K.; Loza, K.; Heggen, M.; Epple, M. An Efficient Method for Covalent Surface Functionalization of Ultrasmall Metallic Nanoparticles by Surface Azidation Followed by Copper-Catalyzed Azide-Alkyne Cycloaddition (Click Chemistry). ChemNanoMat, 2021, 7(12), 1330–1339. doi: 10.1002/cnma.202100359
  74. Li, L.; Huang, K.-L.; Gao, Y.; Cui, Y.; Wang, G.; Elrod, N. D.; Li, Y.; Chen, Y. E.; Ji, P.; Peng, F.; Russell, W. K.; Wagner, E. J.; Li, W. An Atlas of Alternative Polyadenylation Quantitative Trait Loci Contributing to Complex Trait and Disease Heritability. Nat Genet, 2021, 53(7), 994–1005. doi: 10.1038/s41588-021-00864-5
  75. Shirasu, T.; Yodsanit, N.; Xie, X.; Zhao, Y.; Wang, Y.; Xie, R.; Huang, Y.; Wang, B.; Urabe, G.; Gong, S.; Guo, L.-W.; Kent, K. C. An Adventitial Painting Modality of Local Drug Delivery to Abate Intimal Hyperplasia. Biomaterials, 2021, 275, 120968. doi: 10.1016/j.biomaterials.2021.120968
  76. Marotta, N. P.; Ara, J.; Uemura, N.; Lougee, M. G.; Meymand, E. S.; Zhang, B.; Petersson, E. J.; Trojanowski, J. Q.; Lee, V. M.-Y. Alpha-Synuclein from Patient Lewy Bodies Exhibits Distinct Pathological Activity That Can Be Propagated in Vitro. Acta Neuropathologica Communications, 2021, 9(1), 188. doi: 10.1186/s40478-021-01288-2
  77. Kohli, J.; Wang, B.; Brandenburg, S. M.; Basisty, N.; Evangelou, K.; Varela-Eirin, M.; Campisi, J.; Schilling, B.; Gorgoulis, V.; Demaria, M. Algorithmic Assessment of Cellular Senescence in Experimental and Clinical Specimens. Nat Protoc, 2021, 16(5), 2471–2498. doi: 10.1038/s41596-021-00505-5
  78. Long, M.; Liu, X.; Huang, X.; Lu, M.; Wu, X.; Weng, L.; Chen, Q.; Wang, X.; Zhu, L.; Chen, Z. Alendronate-Functionalized Hypoxia-Responsive Polymeric Micelles for Targeted Therapy of Bone Metastatic Prostate Cancer. Journal of Controlled Release, 2021, 334, 303–317. doi: 10.1016/j.jconrel.2021.04.035
  79. Moore, C.; Borum, R. M.; Mantri, Y.; Xu, M.; Fajtová, P.; O’Donoghue, A. J.; Jokerst, J. V. Activatable Carbocyanine Dimers for Photoacoustic and Fluorescent Detection of Protease Activity. ACS Sens., 2021, 6(6), 2356–2365. doi: 10.1021/acssensors.1c00518
  80. Valero, J.; Civit, L.; Dupont, D. M.; Selnihhin, D.; Reinert, L. S.; Idorn, M.; Israels, B. A.; Bednarz, A. M.; Bus, C.; Asbach, B.; Peterhoff, D.; Pedersen, F. S.; Birkedal, V.; Wagner, R.; Paludan, S. R.; Kjems, J. A Serum-Stable RNA Aptamer Specific for SARS-CoV-2 Neutralizes Viral Entry. Proc. Natl. Acad. Sci. U.S.A., 2021, 118(50), e2112942118. doi: 10.1073/pnas.2112942118
  81. Dai, C.; Reyes-Ordoñez, A.; You, J.-S.; Chen, J. A Non-Translational Role of Threonyl-TRNA Synthetase in Regulating JNK Signaling during Myogenic Differentiation. The FASEB Journal, 2021, 35(10), e21948. doi: 10.1096/fj.202101094R
  82. Helal, D. O.; Rouatbi, N.; Han, S.; Tzu-Wen Wang, J.; Walters, A. A.; Abdel-Mottaleb, M. M. A.; Kamel, A. O.; Geneidi, A.-S.; Awad, G. A. S.; Al-Jamal, K. T. A Natural Protein Based Platform for the Delivery of Temozolomide Acid to Glioma Cells. European Journal of Pharmaceutics and Biopharmaceutics, 2021, 169, 297–308. doi: 10.1016/j.ejpb.2021.10.007
  83. Taira, Y.; Shimoji, Y.; Nakasone, T.; Arakaki, Y.; Nakamoto, T.; Kinjo, T.; Kudaka, W.; Mekaru, K.; Aoki, Y. A High-Risk Gestational Trophoblastic Neoplasia Derived from a Complete Hydatidiform Mole with Coexisting Fetus Identified by Short Tandem Repeats Analysis: A Case Report. Case Reports in Women’s Health, 2021, 31, e00336. doi: 10.1016/j.crwh.2021.e00336
  84. Ye, Z.; Zhang, Y.; Liu, Y.; Liu, Y.; Tu, J.; Shen, Y. EGFR Targeted Cetuximab-Valine-Citrulline (vc)-Doxorubicin Immunoconjugates- Loaded Bovine Serum Albumin (BSA) Nanoparticles for Colorectal Tumor Therapy. IJN, 2021, 16, 2443–2459. doi: 10.2147/IJN.S289228
  85. Tan, R.; Tian, D.; Liu, J.; Wang, C.; Wan, Y. Doxorubicin-Bound Hydroxyethyl Starch Conjugate Nanoparticles with PH/Redox Responsive Linkage for Enhancing Antitumor Therapy. IJN, 2021, 16, 4527–4544. doi: 10.2147/IJN.S314705
  86. Sivkina, A. L.; Feofanov, A. V.; Kirpichnikov, M. P.; Akhtar, M. S.; Studitsky, V. M. Role of the Nhp6 Protein in Nucleosome Unfolding by the FACT Factor. Moscow Univ. Biol.Sci. Bull., 2021, 76(4), 191–195. doi: 10.3103/S009639252104012X
  87. McCandless, K.; Mishra, S.; Stiltner, J.; Feldman, K. S.; Yagi, H.; Yurko, R.; Islam, K.; Brown, J. M.; Frizzell, R.; Zahid, M. Novel Lung Targeting Cell Penetrating Peptides as Vectors for Delivery of Therapeutics. Research Square, 2021, preprint. doi: 10.21203/rs.3.rs-1056707/v1
  88. Zahid, M.; McCandless, K.; Mishra, S.; Stiltner, J.; Feldman, K.; Yagi, H.; Yurko, R.; Islam, K.; Brown, J.; Frizzell, R. Novel Lung Targeting Cell Penetrating Peptides as Vectors for Delivery of Therapeutics. Research Square, 2021, preprint. doi: 10.21203/rs.3.rs-1056707/v1
  89. Zanon, P.R.A.; Yu, F.; Musacchio, P.; Lewald, L.; Zollo, M.; Krauskopf, K.; Mrdović, D.; Raunft, P.; Maher, T.E.; Cigler, M.; Chang, C.; Lang, K.; Toste, F.D.; Nesvizhskii, A.I.; Hacker, S.M. Profiling the proteome-wide selectivity of diverse electrophiles. ChemRxiv, 2021, preprint. doi: 10.33774/chemrxiv-2021-w7rss-v2
  90. Baker, Y. R.; Yuan, L.; Chen, J.; Belle, R.; Carlisle, R.; El-Sagheer, A. H.; Brown, T. Expanding the Chemical Functionality of DNA Nanomaterials Generated by Rolling Circle Amplification. Nucleic Acids Research, 2021, 49(16), 9042–9052. doi: 10.1093/nar/gkab720
  91. Yang, M.; Sun, R.; Deng, P.; Yang, Y.; Wang, W.; Liu, J.-J. G.; Chen, C. Nonspecific Interactions between SpCas9 and DsDNA Sites Located Downstream of the PAM Mediate Facilitated Diffusion to Accelerate Target Search. Chem. Sci, 2021, 12(38), 12776–12784. doi: 10.1039/D1SC02633J
  92. Si, Y.; Kim, S.; Ou, J.; Lu, Y.; Ernst, P.; Chen, K.; Whitt, J.; Carter, A. M.; Markert, J. M.; Bibb, J. A.; Chen, H.; Zhou, L.; Jaskula-Sztul, R.; Liu, X. Anti-SSTR2 Antibody-Drug Conjugate for Neuroendocrine Tumor Therapy. Cancer Gene Ther, 2021, 28(7–8), 799–812. doi: 10.1038/s41417-020-0196-5
  93. Sasaki, K.; Harada, M.; Yoshikawa, T.; Tagawa, H.; Harada, Y.; Yonemitsu, Y.; Ryujin, T.; Kishimura, A.; Mori, T.; Katayama, Y. Fc-Binding Antibody-Recruiting Molecules Targeting Prostate-Specific Membrane Antigen: Defucosylation of Antibody for Efficacy Improvement. ChemBioChem, 2021, 22(3), 496–500. doi: 10.1002/cbic.202000577
  94. Pishesha, N.; Harmand, T.; Smeding, L. Y.; Ma, W.; Ludwig, L. S.; Janssen, R.; Islam, A.; Xie, Y. J.; Fang, T.; McCaul, N.; Pinney, W.; Sugito, H. R.; Rossotti, M. A.; Gonzalez-Sapienza, G.; Ploegh, H. L. Induction of Antigen-Specific Tolerance by Nanobody–Antigen Adducts That Target Class-II Major Histocompatibility Complexes. Nature Biomedical Engineering, 2021, 5(11), 1389–1401. doi: 10.1038/s41551-021-00738-5
  95. Yu, J.-H.; Steinberg, I.; Davis, R.M.; Malkovskiy, A.V.; Zlitni, A.; Radzyminski, R.K.; Jung, K.O.; Chung, D.T.; Curet, L.D.; D'Souza, A.L.; Chang, E.; Rosenberg, J.; Campbell, J.; Frostig, H.; Park, S.M.; Pratx, G.; Levin, C.; Gambhir, S.S. Noninvasive and Highly Multiplexed Five-Color Tumor Imaging of Near-Infrared Resonant Surface-Enhanced Raman Nanoparticles In Vivo. ACS Nano, 2021, 15(12), 19956-19969. doi: 10.1021/acsnano.1c07470
  96. Carter, J.G.; Iturbe, L.O.; Duprey, J.-L.H.A.; Carter, I.R.; Southern, C.D.; Rana, M.; Whalley, C.M.; Bosworth, A.; Beggs, A.D.; Hicks, M.R.; Tucker, J.H.R.; Dafforn, T.R. Ultrarapid detection of SARS-CoV-2 RNA using a reverse transcription-free exponential amplification reaction, RTF-EXPAR. Proceedings of the National Academy of Sciences, 2021, 118(35), e2100347118. doi: 10.1073/pnas.2100347118
  97. Koide, H.; Okishima, A.; Hoshino, Y.; Kamon, Y.; Yoshimatsu, K.; Saito, K.; Yamauchi, I.; Ariizumi, S.; Zhou, Y.; Xiao, T.-H.; Goda, K.; Oku, N.; Asai, T.; Shea, K. Synthetic hydrogel nanoparticles for sepsis therapy. Nature Communications, 2021, 12(1), 5552. doi: 10.1038/s41467-021-25847-2
  98. Rudack, T.; Teuber, C.; Scherlo, M.; Güldenhaupt, J.; Schartner, J.; Lübben, M.; Klare, J.P.; Gerwert, K.; Kötting, C. The Ras Dimer Structure. Chemical Science, 2021, 12(23), 8178-8189. doi: 10.1039/d1sc00957e
  99. Song, S.; Mason, A.; Post, R.; de Corato, M.; Mestre, R.; Yewdall, A.; Cao, S.; van der Hofstad, R.; Sanchez, S.; Abdelmohsen, L.; van Hest, J.C. Engineering transient dynamics of artificial cells by stochastic distribution of enzymes. Nature Communications, 2021, 12(1), 6897. doi: 10.1038/s41467-021-27229-0
  100. Guarin, M.; Faelens, R.; Giusti, A.; De Croze, N.; Léonard, M.; Cabooter, D.; Annaert, P.; de Witte, P.; Ny, A. Spatiotemporal Imaging and Pharmacokinetic of Fluorescent Compounds in Zebrafish Eleuthero-Embryos After Different Routes of Administration. Scientific Reports, 2021, 11(1), 12229. doi: 10.1038/s41598-021-91612-6.
  101. Wells, C.I.; Al-Ali, H.; Andrews, D.M.; Asquith, C.R.M.; Axtman, A.D.; Chung, M.; Dikic, I.; Ebner, D.; Elkins, J.M.; Ettmayer, P.; Fischer, C.; Frederiksen, M.; Gray, N.S.; Hatch, S.; Knapp, S.; Lee, S.; Lücking, U.; Michaelides, M.; Mills, C.E.; Müller, S.; Owen, D.; Picado, A.; Ramadan, K.; Saikatendu, K.S.; Schröder, M.; Stolz, A.; Tellechea, M.; Treiber, D.K.; Turunen, B.J.; Vilar, S.; Wang, J.; Zuercher, W.J.; Willson, T.M.; Drewry, D.H. The Kinase Chemogenomic Set (KCGS): An open science resource for kinase vulnerability identification. International Journal of Molecular Sciences, 2021, 22(2), 566. doi: 10.3390/ijms22020566
  102. Zakharenkova, S.A.; Katkova, E.A.; Doroshenko, I.A.; Kriveleva, A.S.; Lebedeva, A.N.; Vidinchuk, T.A.; Shik, A.V.; Abramchuk, S.S.; Podrugina, T.A.; Beklemishev, M.K. Aggregation- based fluorescence amplification strategy: "turn-on" sensing of aminoglycosides using near-IR carbocyanine dyes and pre-micellar surfactants. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2021, 247, 119109. doi: 10.1016/j.saa.2020.119109
  103. Petrunina, N.A.; Lebedev, V.V.; Kirillova, Y.G.; Aralov, A..V.; Varizhuk, A.M.; Sardushkin, M.V. DNA Intercalated Motifs with Non-Nucleoside Inserts. Russian Journal of Bioorganic Chemistry, 2021, 47(6), 1341–1344. doi: 10.1134/S1068162021060212
  104. Stepanova, I.A.; Lebedeva, A.N.; Shik, A..V.; Skorobogatov, E.V.; Beklemishev, M.K. Recognition and Determination of Sulfonamides by Near-IR Fluorimetry Using Their Effect on the Rate of the Catalytic Oxidation of a Carbocyanine Dye by Hydrogen Peroxide. Journal of Analytical Chemistry, 2021, 76(12), 1399–1407. doi: 10.1134/S1061934821120121
  105. Huang, S.-K.; Whitney, P.H.; Dutta, S.; Shvartsman, S.Y.; Rushlow, C.A. Spatial organization of transcribing loci during early genome activation in Drosophila. Current Biology, 2021, 31(22), 5102–5110. doi: 10.1016/j.cub.2021.09.027
  106. do Valle Gomes, M.Z.; Masdeu, G.; Eiring, P.; Kuhlemann, A.; Sauer, M.; Åkerman, B:; Palmqvist, A.E.C. Improved biocatalytic cascade conversion of CO2 to methanol by enzymes Co-immobilized in tailored siliceous mesostructured cellular foams. Catalysis Science & Technology, 2021, 11(21), 6952–6959. doi: 10.1039/D1CY01354H
  107. Lee, R.; Erstling, J.A.; Hinckley, J.A.; Chapman, D.V.; Wiesner, U.B. Addressing Particle Compositional Heterogeneities in Super-Resolution-Enhanced Live-Cell Ratiometric pH Sensing with Ultrasmall Fluorescent Core–Shell Aluminosilicate Nanoparticles. Advanced Functional Materials, 2021, 31(45), 2106144. doi: 10.1002/adfm.202106144
  108. Mu, Q.; Lin, G.; Jeon, M.; Wang, H.; Chang, F.-C.; Revia, R.A.; Yu, J.; Zhang, M. Iron oxide nanoparticle targeted chemo-immunotherapy for triple negative breast cancer. Materials Today, 2021, 50, 149–169. doi: 10.1016/j.mattod.2021.08.002
  109. Abbasov, M.E.; Kavanagh, M.E.; Ichu, T.-A.; Lazear, M.R.; Tao, Y.; Crowley, V.M.; am Ende, C.W.; Hacker, S.M.; Ho, J.; Dix, M.M.; Suciu, R.; Hayward, M.M.; Kiessling, L.L.; Cravatt, B.F. A proteome-wide atlas of lysine-reactive chemistry. Nature Chemistry, 2021, 13(11), 1081–1092. doi: 10.1038/s41557-021-00765-4
  110. Lee, J.-R.; Park, B.-W.; Park, J.-H.; Lim, S.; Kwon, S.P.; Hwang, J.-W.; Kim, H.; Park, H.-J.; Kim, B.-S. Local delivery of a senolytic drug in ischemia and reperfusion-injured heart attenuates cardiac remodeling and restores impaired cardiac function. Acta Biomaterialia, 2021, 135, 520--533. doi: 10.1016/j.actbio.2021.08.028
  111. Igarashi, K.; Cabral, H.; Hong, T.; Anraku, Y.; Mpekris, F.; Stylianopoulos, T.; Khan, T.; Matsumoto, A.; Kataoka, K.; Matsumoto, Y.; Yamasoba, T. Vascular Bursts Act as a Versatile Tumor Vessel Permeation Route for Blood-Borne Particles and Cells. Small, 2021, 17(42), 2103751. doi: 10.1002/smll.202103751
  112. Nkanga, C.I.; Chung, Y.H.; Shukla, S.; Zhou, J.; Jokerst, J.V.; Steinmetz, N.F. The in vivo fate of tobacco mosaic virus nanoparticle theranostic agents modified by the addition of a polydopamine coat. Biomaterials Science, 2021, 9(21), 7134–7150. doi: 10.1039/D1BM01113H
  113. Schmidt, V.; Horváth, C.; Dong, H.; Blüher, M.; Qvist, P.; Wolfrum, C.; Willnow, T.E. SORLA is required for insulin-induced expansion of the adipocyte precursor pool in visceral fat. Journal of Cell Biology, 2021, 220(12), e202006058. doi: 10.1083/jcb.202006058
  114. Lobov, A.A.; Babkina, I.Y.; Danilov, L.G.; Masharskiy, A.E.; Predeus, A.V.; Mikhailova, N.A.; Granovitch, A.I.; Maltseva, A.L. Species-Specific Proteins in the Oviducts of Snail Sibling Species: Proteotranscriptomic Study of Littorina fabalis and L. obtusata. Biology, 2021, 10(11), 1087. doi: 10.3390/biology10111087
  115. Francis, D.M. Manspeaker, M.P.; Archer, P.A.; Sestito, L.F.; Heiler, A.J.; Schudel, A.; Thomas, S.N. Drug-eluting immune checkpoint blockade antibody-nanoparticle conjugate enhances locoregional and systemic combination cancer immunotherapy through T lymphocyte targeting. Biomaterials, 2021, 279, 121184. doi: 10.1016/j.biomaterials.2021.121184
  116. Nascimento, A.; Pedro, M.N.S.; Pinto, I.F.; Aires-Barros, M.R.; Azevedo, A.M. Microfluidics as a high-throughput solution for chromatographic process development – The complexity of multimodal chromatography used as a proof of concept. Journal of Chromatography A, 2021, 1658, 462618. doi: 10.1016/j.chroma.2021.462618
  117. Bauer, B.W.; Davidson, I.F.; Canena, D.; Wutz, G.; Tang, W.; Litos, G.; Horn, S.; Hinterdorfer, P.; Peters, J.-M. Cohesin mediates DNA loop extrusion by a “swing and clamp” mechanism. Cell, 2021, 184(21), 5448--5464.e22. doi: 10.1016/j.cell.2021.09.016
  118. Kong, S.M.; Costa, D.F.; Jagielska, A.; Van Vliet, K.J.; Hammond, P.T. Stiffness of targeted layer-by-layer nanoparticles impacts elimination half-life, tumor accumulation, and tumor penetration. Proceedings of the National Academy of Sciences, 2021, 118(42), e2104826118. doi: 10.1073/pnas.2104826118
  119. Nobori, T.; Kishimura, A.; Mori, T.; Katayama, Y. A FRET-based Protein Kinase Assay using Phos-tag-modified Quantum Dots and Fluorophore-labeled Peptides. Analytical Sciences, 2021, 37(10), 1361–1366. doi: 10.2116/analsci.20P443
  120. van Beek, L.F.; Welzen, P.L.W.; Teufel, L.U.; Joosten, I.; Diavatopoulos, D.A.; van Hest, J.; de Jonge, M.I. Bimodal Targeting of Human Leukocytes by Fc- and CpG-Decorated Polymersomes to Tune Immune Induction. Biomacromolecules, 2021, 22(10), 4422–4433. doi: 10.1021/acs.biomac.1c00985
  121. Li, D.; Taylor, D.H.; van Wolfswinkel, J.C. PIWI-mediated control of tissue-specific transposons is essential for somatic cell differentiation. Cell Reports, 2021, 37(1), 109776. doi: 10.1016/j.celrep.2021.109776
  122. Liu, Q.; Tian, J.; Liu, J.; Zhu, M.; Gao, Z.; Hu, X.; Midgley, A.C.; Wu, J.; Wang, Xi.; Kong, D.; Zhuang, J.; Liu, J.; Yan, X.; Huang, X. Modular Assembly of Tumor-Penetrating and Oligomeric Nanozyme Based on Intrinsically Self-Assembling Protein Nanocages. Advanced Materials, 2021, 33(39), 2103128. doi: 10.1002/adma.202103128
  123. Umebara, M.; Sugai, N.; Murayama, K.; Sugawara, T.; Akashi, Y.; Morita, Y.; Kato, R.; Komatsu, T. Catalase-driven protein microtube motors with different exterior surfaces as ultrasmall biotools. Materials Advances, 2021, 2(19), 6428–6438. doi: 10.1039/D1MA00610J
  124. Yang, X.; Xia, X.; Xia, X.-X.; Sun, Z.; Yan, D. Improving Targeted Delivery and Antitumor Efficacy with Engineered Tumor Necrosis Factor-Related Apoptosis Ligand-Affibody Fusion Protein. Molecular Pharmaceutics, 2021, 18(10), 3854–3861. doi: 10.1021/acs.molpharmaceut.1c00483
  125. Özcan, A.; Krajeski, R.; Ioannidi, E.; Lee, B.; Gardner, A.; Makarova, K.S.; Koonin, E.V.; Abudayyeh, O.O.; Gootenberg, J.S. Programmable RNA targeting with the single-protein CRISPR effector Cas7-11. Nature, 2021, 597(7878), 720–725. doi: 10.1038/s41586-021-03886-5
  126. Wang, Q.; Gao, Z.; Zhong, Q.-Z.; Wang, N.; Mei, H.; Dai, Q.; Cui, J.; Hao, J. Encapsulation of Enzymes in Metal{\textendash}Phenolic Network Capsules for the Trigger of Intracellular Cascade Reactions. Langmuir, 2021, 37(38), 11292–11300. doi: 10.1021/acs.langmuir.1c01821
  127. Puthenveetil, R.; Lun, C.M.; Murphy, R.E.; Healy, L.B.; Vilmen, G.; Christenson, E.T.; Freed, E.O.; Banerjee, A. S-acylation of SARS-CoV-2 Spike Protein: Mechanistic Dissection, In Vitro Reconstitution and Role in Viral Infectivity. Journal of Biological Chemistry, 2021, 297(4), 101112. doi: 10.1016/j.jbc.2021.101112
  128. Dao, N.V.; Ercole, F.; Li, Y.; Davis, T.P.; Kaminskas, L.M.; Sloan, E.K.; Quinn, J.F.; Whittaker, M.R. Nitroxide-functional PEGylated nanostars arrest cellular oxidative stress and exhibit preferential accumulation in co-cultured breast cancer cells. Journal of Materials Chemistry B, 2021, 9(37), 7805–7820. doi: 10.1039/D1TB00812A
  129. Baranova, M.N.; Babikova, P.A.; Kudzhaev, A.M.; Mokrushina, Y.A.; Belozerova, O.A.; Yunin, M.A.; Kovalchuk, S.; Gabibov, A.G.; Smirnov, I.V.; Terekhov, S.S. Live Biosensors for Ultrahigh-Throughput Screening of Antimicrobial Activity against Gram-Negative Bacteria. Antibiotics, 2021, 10(10), 1161. doi: 10.3390/antibiotics10101161
  130. Morozov, V.N.; Klimovich, M.A.; Kolyvanova, M.A.; Dement'eva, O.V.; Rudoy, V.M.; Kuzmin, V.A. Interaction of Gold Nanoparticles with Cyanine Dyes in Cholesteric DNA Submicroparticles. High Energy Chemistry, 2021, 55(5), 341–348. doi: 10.1134/S0018143921050088
  131. Wang, S.; Latallo, M.J.; Zhang, Z.; Huang, B.; Bobrovnikov, D.G.; Dong, D.; Livingston, N.M.; Tjoeng, W.; Hayes, L.R.; Rothstein, J.D.; Ostrow, L.W.; Wu, B.; Sun, S. Nuclear export and translation of circular repeat-containing intronic RNA in C9ORF72-ALS/FTD. Nature Communications, 2021, 12(1), 4908. doi: 10.1038/s41467-021-25082-9
  132. Woodford, M.R.; Baker-Williams, A.J.; Sager, R.A.; Backe, S.J.; Blanden, A.R.; Hashmi, F.; Kancherla, P.; Gori, A.; Loiselle, D.R.; Castelli, M.; Serapian, S.A.; Colombo, G.; Haystead, T.A.; Jensen, S.M.; Stetler-Stevenson, W.G.; Loh, S.N.; Schmidt, L.S.; Linehan, W.M.; Bah, A.; Bourboulia, D.; Bratslavsky, G.; Mollapour, M. The tumor suppressor folliculin inhibits lactate dehydrogenase A and regulates the Warburg effect. Nature Structural & Molecular Biology, 2021, 28(8), 662–670. doi: 10.1038/s41594-021-00633-2
  133. Guo, H.; Liu, L.; Hu, Q.; Dou, H. Mixed Solvent Method for Improving the Size Uniformity and Cargo-Loading Efficiency of ZIF-8 Nanoparticles. Langmuir, 2021, 37(33), 10089–10099. doi: 10.1021/acs.langmuir.1c01399
  134. Lo, Y.-C.; Lin, W.-J. Benefit of a Short Chain Peptide as a Targeting Ligand of Nanocarriers for a Brain-Driven Purpose. Pharmaceutics, 2021, 13(8), 1249. doi: 10.3390/pharmaceutics13081249
  135. Saifutiarova, A.E.; Fedorov, Y.V.; Tsvetkov, V.B.; Rustamova, D.A.; Gulakova, E.N.; Chmelyuk, N.S.; Abakumov, M.A.; Aliev, T.M.; Fedorova, O.A. Photochemical synthesis, intercalation with DNA and antitumor evaluation in vitro of benzo[d]thiazolo[3,2-a]quinolin-10-ium derivatives. Bioorganic Chemistry, 2021, 115, 105267. doi: 10.1016/j.bioorg.2021.105267
  136. Carter, J.G.; Iturbe, L.O.; Duprey, J.-L.H.A.; Carter, I.R.; Southern, C.D.; Rana, M.; Whalley, C.M.; Bosworth, A.; Beggs, A.D.; Hicks, M.R.; Tucker, J.H.R.; Dafforn, T.R. Ultrarapid detection of SARS-CoV-2 RNA using a reverse transcription{\textendash}free exponential amplification reaction, RTF-EXPAR. Proceedings of the National Academy of Sciences of the U.S.A., 2021, 118(35), e2100347118. doi: 10.1073/pnas.2100347118
  137. Tamarov, K.; Wang, J.T.W.; Kari, J.; Happonen, E.; Vesavaara, I.; Niemelä, M.; Perämäki, P.; Al-Jamal, K.T.; Xu, W.; Lehto, V.-P. Comparison between Fluorescence Imaging and Elemental Analysis to Determine Biodistribution of Inorganic Nanoparticles with Strong Light Absorption. ACS Applied Materials & Interfaces, 2021, 13(34), 40392–40400. doi: 10.1021/acsami.1c11875
  138. Koide, H.; Okishima, A.; Hoshino, Y.; Kamon, Y.; Yoshimatsu, K.; Saito, K.; Yamauchi, I.; Ariizumi, S.; Zhou, Y.; Xiao, T.-H.; Goda, K.; Oku, N.; Asai, T.; Shea, K.J. Synthetic hydrogel nanoparticles for sepsis therapy. Nature Communications, 2021, 12(1), 5552. doi: 10.1038/s41467-021-25847-2
  139. Koch, P.D.; Quintana, J.; Ahmed, M.S.; Kohler, R.H.; Weissleder, R. Small Molecule Imaging Agent for Mutant KRAS G12C. Advanced Therapeutics, 2021, 4(5), 2000290. doi: 10.1002/adtp.202000290
  140. Kamzabek, D.; Le Dé, B.; Coche-Guérente, L.; Miomandre, F.; Dubacheva, G.V. Thermoresponsive Fluorescence Switches Based on Au@pNIPAM Nanoparticles. Langmuir, 2021, 37(37), 10971–10978. doi: 10.1021/acs.langmuir.1c01397
  141. Hong, T.; Miyazaki, T.; Matsumoto, A.; Koji, K.; Miyahara, Y.; Anraku, Y.; Cabral, H. Phosphorylcholine-Installed Nanocarriers Target Pancreatic Cancer Cells through the Phospholipid Transfer Protein. ACS Biomaterials Science & Engineering, 2021, 7(9), 4439–4445. doi: 10.1021/acsbiomaterials.1c00730
  142. Yu, S.; Yang, H.; Li, T.; Pan, H.; Ren, S.; Luo, G.; Jiang, J.; Yu, L.; Chen, B.; Zhang, Y.; Wang, S.; Tian, R.; Zhang, T.; Zhang, S.; Chen, Y.; Yuan, Q.; Ge, S.; Zhang, J.; Xia, N. Efficient intracellular delivery of proteins by a multifunctional chimaeric peptide in vitro and in vivo. Nature Communications, 2021, 12(1), 5131. doi: 10.1038/s41467-021-25448-z
  143. Song, J.W.; Nam, H.S.; Ahn, J.W.; Park, H.-S.; Kang, D.O.; Kim, H.J.; Kim, Y.H.; Han, J.; Choi, J.Y.; Lee, S.-Y.; Kim, S.; Oh, W.-Y.; Yoo, H.; Park, K.; Kim, J.W. Macrophage targeted theranostic strategy for accurate detection and rapid stabilization of the inflamed high-risk plaque. Theranostics, 2021, 11(18), 8874–8893. doi: 10.7150/thno.59759
  144. Hurley, C.M.; Kraut, D.A. Determination of Proteasomal Unfolding Ability. Methods in Molecular Biology, 2021, 2365, 217–244. doi: 10.1007/978-1-0716-1665-9_12
  145. Wiktor, J.; Gynnå, A.H.; Leroy, P.; Larsson, J.; Coceano, G.; Testa, I.; Elf, J. RecA finds homologous DNA by reduced dimensionality search. Nature, 2021, 597(7876), 426–429. doi: 10.1038/s41586-021-03877-6
  146. Svetlova, J.; Sardushkin, M.; Kolganova, N.; Timofeev, E. Recognition Interface of the Thrombin Binding Aptamer Requires Antiparallel Topology of the Quadruplex Core. Biomolecules, 2021, 11(9), 1332. doi: 10.3390/biom11091332
  147. Demin, A.M.; Pershina, A.G.; Minin, A.S.; Brikunova, O.Y.; Murzakaev, A.M.; Perekucha, N.A.; Romashchenko, A.V.; Shevelev, O.B.; Uimin, M.A.; Byzov, I.V.; Malkeyeva, D.; Kiseleva, E.; Efimova, L.V.; Vtorushin, S.V.; Ogorodova, L.M.; Krasnov, V.P. Smart Design of a pH-Responsive System Based on pHLIP-Modified Magnetite Nanoparticles for Tumor MRI. ACS Applied Materials & Interfaces, 2021, 13(31), 36800–36815. doi: 10.1021/acsami.1c07748
  148. Rosier, N.; Grätz, L.; Schihada, H.; Möller, J.; Işbilir, A.; Humphrys, L.J.; Nagl, M.; Seibel, U.; Lohse, M.J.; Pockes, S. A Versatile Sub-Nanomolar Fluorescent Ligand Enables NanoBRET Binding Studies and Single-Molecule Microscopy at the Histamine H3 Receptor. Journal of Medicinal Chemistry, 2021, 64(15), 11695–11708. doi: 10.1021/acs.jmedchem.1c01089
  149. Zhuo, X.-Z.; Bai, K.; Wang, Y.; Liu, P.; Xi, W.; She, J.; Liu, J. Long-chain non-coding RNA-GAS5 / hsa-miR-138-5p attenuates high glucose-induced cardiomyocyte damage by targeting CYP11B2. Bioscience Reports, 2021, 41(9), BSR20202232. doi: 10.1042/BSR20202232
  150. Son, S.; Shin, J.M.; Shin, S.; Kim, C.H.; Lee, J.A.; Ko, H.; Lee, E.S.; Jung, J.M:; Kim, J.; Park, J.H. Repurposing macitentan with nanoparticle modulates tumor microenvironment to potentiate immune checkpoint blockade. Biomaterials, 2021, 276, 121058. doi: 10.1016/j.biomaterials.2021.121058
  151. Buehler, P.W.; Swindle, D.; Pak, D.I.; Ferguson, S.K.; Majka, S.M.; Karoor, V.; Moldovan, R.; Sintas, C.; Black, J.; Gentinetta, T.; Buzzi, R.M.; Vallelian, F.; Wassmer, A.; Edler, M.; Bain, J.; Schu, D.; Hassell, K.; Nuss, R.; Schaer, D.J.; Irwin, D.C. Hemopexin dosing improves cardiopulmonary dysfunction in murine sickle cell disease. Free Radical Biology and Medicine, 2021, 175, 95–107. doi: 10.1016/j.freeradbiomed.2021.08.238
  152. Eliseev, I.E.; Ukrainskaya, V.M.; Yudenko, A.N.; Mikushina, A.D.; Shmakov, S.V.; Afremova, A.I.; Ekimova, V.M.; Vronskaia, A.A.; Knyazev, N.A.; Shamova, O.V. Targeting ErbB3 Receptor in Cancer with Inhibitory Antibodies from Llama. Biomedicines, 2021, 9(9), 1106. doi: 10.3390/biomedicines9091106
  153. Pham, L.M.; Poudel, K.; Phung, C.D.; Nguyen, T.T.; Pandit, M.; Nguyen, H.T.; Chang, J.-H.; Jin, S.G.; Jeong, J.-H.; Ku, S.K.; Choi, H.-G.; Yong, C.S.; Kim, J.O. Preparation and evaluation of dabrafenib-loaded, CD47-conjugated human serum albumin-based nanoconstructs for chemoimmunomodulation. Colloids and Surfaces B: Biointerfaces, 2021, 208, 112093. doi: 10.1016/j.colsurfb.2021.112093
  154. Charoen-Rajapark, P.; Clarke, D.R. Confocal microscopy observations of electrical pre-breakdown of bi-layer elastomer dielectrics. Extreme Mechanics Letters, 2021, 49, 101473. doi: 10.1016/j.eml.2021.101473
  155. Nosella, M.L.; Tereshchenko, M.; Pritišanac, I.; Chong, P.A.; Toretsky, J.A.; Lee, H.O.; Forman-Kay, J.D. O-Linked-N-Acetylglucosaminylation of the RNA-Binding Protein EWS N-Terminal Low Complexity Region Reduces Phase Separation and Enhances Condensate Dynamics. Journal of the American Chemical Society, 2021, 143(30), 11520–11534. doi: 10.1021/jacs.1c04194
  156. Yamansarov, E.Y.; Lopatukhina, E.V.; Evteev, S.A.; Skvortsov, D.A.; Lopukhov, A.V.; Kovalev, S.V.; Vaneev, A.N.; Shkil', D.O.; Akasov, R.A.; Lobov, A,.N.; Naumenko, V.A.; Pavlova, E.N.; Ryabaya, O.O.; Burenina, O.Y.; Ivanenkov, Y.A.; Klyachko, N.L.; Erofeev, A.S.; Gorelkin, P.V.; Beloglazkina, E.K.; Majouga, A. Discovery of Bivalent GalNAc-Conjugated Betulin as a Potent ASGPR-Directed Agent against Hepatocellular Carcinoma. Bioconjugate Chemistry, 2021, 32(4), 763–781. doi: 10.1021/acs.bioconjchem.1c00042
  157. Tao, Y.; Xie, J.; Zhong, Q.; Wang, Y.; Zhang, S.; Luo, F.; Wen, F.; Xie, J.; Zhao, J.; Sun, X.; Long, H.; Ma, J.; Zhang, Q.; Long, J.; Fang, X.; Lu, Y.; Li, D.; Li, M.; Zhu, J.; Sun, B.; Li, G.; Diao, J.; Liu, C. A novel partially open state of {SHP}2 points to a "multiple gear" regulation mechanism. Journal of Biological Chemistry, 2021, 296, 100538. doi: 10.1016/j.jbc.2021.100538
  158. Kim, H.; Yuk, S.A.; Dieterly, A.M.; Kwon, S.; Park, J.; Meng, F.; Gadalla, H.H.; Cadena, M.J.; Lyle, L.T.; Yeo, Y. Nanosac, a Noncationic and Soft Polyphenol Nanocapsule, Enables Systemic Delivery of siRNA to Solid Tumors. ACS Nano, 2021, 15(3), 4576–4593. doi: 10.1021/acsnano.0c08694
  159. Bagert, J.D.; Mitchener, M.M.; Patriotis, A.L.; Dul, B.E.; Wojcik, F.; Nacev, B.A.; Feng, L.; Allis, C.D.; Muir, T.W. Oncohistone mutations enhance chromatin remodeling and alter cell fates. Nature Chemical Biology, 2021, 17(4), 403–411. doi: 10.1038/s41589-021-00738-1
  160. Nong, J.; Kang, K.; Shi, Q.; Zhu, X.; Tao, Q.; Chen, Y.-G. Phase separation of Axin organizes the β-catenin destruction complex. Journal of Cell Biology, 2021, 220(4), 202012112. doi: 10.1083/jcb.202012112
  161. Barrios-Hernández, M.L.; Bettinelli, C.; Mora-Cabrera, K.; Vanegas-Camero, M.-C.; Garcia, H.; van de Vossenberg, J.; Prats, D.; Brdjanovic, D.; van Loosdrecht, M.C.M.; Hooijmans, C.M. Unravelling the removal mechanisms of bacterial and viral surrogates in aerobic granular sludge systems. Water Research, 2021, 195, 116992. doi: 10.1016/j.watres.2021.116992
  162. Radzisheuskaya, A.; Shliaha, P.V.; Grinev, V.V.; Shlyueva, D.; Damhofer, H.; Koche, R.; Gorshkov, V.; Kovalchuk, S.; Zhan, Y.; Rodriguez, K.L.; Johnstone, A.L.; Keogh, M.-C.; Hendrickson, R.C.; Jensen, O.N.; Helin, K. Complex-dependent histone acetyltransferase activity of KAT8 determines its role in transcription and cellular homeostasis. Molecular Cell, 2021, 81(8), 1749–1765. doi: 10.1016/j.molcel.2021.02.012
  163. Wang, Y.; Cottle, W.T.; Wang, H.; Feng, X.A.; Mallon, J.; Gavrilov, M.; Bailey, S.; Ha, T. Genome oligopaint via local denaturation fluorescence in situ hybridization. Molecular Cell, 2021, 81(7), 1566–1577. doi: 10.1016/j.molcel.2021.02.011
  164. So, I.-S.; Kang, J.H.; Hong, J.W.; Sung, S.; Hasan, A.F.; Sa, K.H.; Han, S.W.; Kim, I.S.; Kang, Y.M. A novel apoptosis probe, cyclic ApoPep-1, for in vivo imaging with multimodal applications in chronic inflammatory arthritis. Apoptosis, 2021, 26(3–4), 209–218. doi: 10.1007/s10495-021-01659-z
  165. Robla, S.; Prasanna, M.; Varela-Calviño, R.; Grandjean, C.; Csaba, N. A chitosan-based nanosystem as pneumococcal vaccine delivery platform. Drug Delivery and Translational Research, 2021, 11(2), 581–597. doi: 10.1007/s13346-021-00928-3
  166. Sun, X.; Du, J.D.; Hawley, A.; Tan, A.; Boyd, B.J. Magnetically-stimulated transformations in the nanostructure of PEGylated phytantriol-based nanoparticles for on-demand drug release. Colloids and Surfaces B: Biointerfaces, 2021, 207, 112005. doi: 10.1016/j.colsurfb.2021.112005
  167. Zhang, Q.; Agius, S.C.; Flanigan, S.F.; Uckelmann, M.; Levina, V.; Owen, B.M.; Davidovich, C. PALI1 facilitates DNA and nucleosome binding by PRC2 and triggers an allosteric activation of catalysis. Nature Communications, 2021, 12(1), 4592. doi: 10.1038/s41467-021-24866-3
  168. Kántor, I.; Aparaschivei, D.; Todea, A.; Biró, E.; Babos, G.; Szerényi, D.; Kakasi, B.; Péter, F:; Şişu, Eugen and Feczkó, T. Biocatalytic synthesis of poly[ε-caprolactone-co-(12-hydroxystearate)] copolymer for sorafenib nanoformulation useful in drug delivery. Catalysis Today, 2021, 366, 195–201. doi: 10.1016/j.cattod.2020.05.005
  169. Chiou, A.E.; Hinckley, J.A.; Khaitan, R:; Varsano, N.; Wang, J.; Malarkey, H.F.; Hernandez, C.J.; Williams, R.M.; Estroff, L.A.; Weiner, S.; Addadi, L.; Wiesner, U.B.; Fischbach, C. Fluorescent Silica Nanoparticles to Label Metastatic Tumor Cells in Mineralized Bone Microenvironments. Small, 2021, 17(15), 2001432. doi: 10.1002/smll.202001432
  170. Yang, X.; Wang, Z.; Huang, H.; Ling, S.; Zhang, R.; Zhang, Y.; Chen, G.; Li, C.; Wang, Q. A Targeted Activatable NIR-IIb Nanoprobe for Highly Sensitive Detection of Ischemic Stroke in a Photothrombotic Stroke Model. Advanced Healthcare Materials, 2021, 10(5), 2001544. doi: 10.1002/adhm.202001544
  171. Koch, S.; Seinen, A.-B.; Kamel, M.; Kuckla, D.; Monzel, C.; Kedrov, A.; Driessen, A.J.M. Single-molecule analysis of dynamics and interactions: of the SecYEG translocon. FEBS Journal, 2021, 288(7), 2203–2221. doi: 10.1111/febs.15596
  172. Roberts, S.; Khera, E.; Choi, C.; Navaratna, T.; Grimm, J.; Thurber, G.M.; Reiner, T. Optoacoustic imaging of Glucagon-like Peptide 1 Receptor with a near-infrared exendin-4 analog. Journal of Nuclear Medicine, 2021, 62(6), 839–848. doi: 10.2967/jnumed.120.252262
  173. Geng, S.; Li, Z.; Zhang, R.; Zhou, W.; Luo, G.; Chu, P.K.; Yu, X.-F. Complete ablation of resistant tumors with photosensitive black phosphorus quantum dots-based lipid nanocapsules. Chemical Engineering Journal, 2021, 421, 127879. doi: 10.1016/j.cej.2020.127879
  174. Geng, H.; Zhou, M.; Li, B.; Liu, L.; Yang, X.; Wen, Y.; Yu, H.; Wang, H.; Chen, J.; Chen, L. Metal-drug nanoparticles-mediated osteolytic microenvironment regulation for enhanced radiotherapy of orthotopic osteosarcoma. Chemical Engineering Journal, 2021, 417, 128103. doi: 10.1016/j.cej.2020.128103
  175. Xu, C.; Wang, Y.; Wang, E.; Yan, N.; Sheng, S.; Chen, J.; Lin, L.; Guo, Z.; Tian, H.; Chen, X. Effective Eradication of Tumors by Enhancing Photoacoustic-Imaging-Guided Combined Photothermal Therapy and Ultrasonic Therapy. Advanced Functional Materials, 2021, 31(10), 2009314. doi: 10.1002/adfm.202009314
  176. Nie, T.; He, Z.; Zhu, J.; Chen, K.; Howard, G.P.; Pacheco-Torres, J.; Minn, I.; Zhao, P.; Bhujwalla, Z.M.; Mao, H.-Q.; Liu, L.; Chen, Y. Non-invasive delivery of levodopa-loaded nanoparticles to the brain via lymphatic vasculature to enhance treatment of Parkinson's disease. Nano Research, 2021, 14(8), 2749–2761. doi: 10.1007/s12274-020-3280-0
  177. Ahn, Y.J.; Yun, W.S.; Choi, J.S.; Kim, W.C.; Lee, S.H.; Park, D.J.; Park, J.E.; Key, J.; Seo, Y.J. Biodistribution of poly clustered superparamagnetic iron oxide nanoparticle labeled mesenchymal stem cells in aminoglycoside induced ototoxic mouse model. Biomedical Engineering Letters, 2021, 11(1), 39–53. doi: 10.1007/s13534-020-00181-6
  178. Krchlíková, V.; Mikešová, J.; Geryk, J.; Bařinka, C.; Nexo, E.; Fedosov, S.N.; Kosla, J.; Kučerová, D.; Reinišová, M.; Hejnar, J.; Elleder, D. The avian retroviral receptor Tva mediates the uptake of transcobalamin bound vitamin B12 (cobalamin). Journal of Virology, 2021, 95(8). doi: 10.1128/JVI.02136-20
  179. Slor, G.; Olea, A.R.; Pujals, S.; Tigrine, A.; De La Rosa, V.R.; Hoogenboom, R.; Albertazzi, L.; Amir, R.J. Judging Enzyme-Responsive Micelles by Their Covers: Direct Comparison of Dendritic Amphiphiles with Different Hydrophilic Blocks. Biomacromolecules, 2021, 22(3), 1197–1210. doi: 10.1021/acs.biomac.0c01708
  180. Deckard, C.E.; Sczepanski, J.T. Reversible chromatin condensation by the DNA repair and demethylation factor thymine DNA glycosylase. Nucleic Acids Research, 2021, 49(5), 2450–2459. doi: 10.1093/nar/gkab040
  181. Chariou, P.L.; Beiss, V.; Ma, Y.; Steinmetz, N.F. In situ vaccine application of inactivated CPMV nanoparticles for cancer immunotherapy. Materials Advances, 2021, 2(5), 1644–1656. doi: 10.1039/D0MA00752H
  182. Li, S.; Luo, M.; Wang, Z.; Feng, Q.; Wilhelm, J.; Wang, X.; Li, W.; Wang, J.; Cholka, A.; Fu, Y.-X.; Sumer, B.D.; Yu, H.; Gao, J. Prolonged activation of innate immune pathways by a polyvalent STING agonist. Nature Biomedical Engineering, 2021, 5(5), 455–466. doi: 10.1038/s41551-020-00675-9
  183. Ieong, K.-W.; Indrisiunaite, G.; Prabhakar, A.; Puglisi, J.D.; Ehrenberg, M. N6-Methyladenosines in mRNAs reduce the accuracy of codon reading by transfer RNAs and peptide release factors. Nucleic Acids Research, 2021, 49(5), 2684–2699. doi: 10.1093/nar/gkab033
  184. Schotman, M.J.G.; Peters, M.M.C.; Krijger, G.C.; van Adrichem, I.; de Roos, R.; Bemelmans, J.L.M.; Pouderoijen, M.J.; Rutten, M.G.T.A.; Neef, K.; Chamuleau, S.A.J.; Dankers, P.Y.W. In Vivo Retention Quantification of Supramolecular Hydrogels Engineered for Cardiac Delivery. Advanced Healthcare Materials, 2021, 10(10), e2001987. doi: 10.1002/adhm.202001987
  185. Kochappan, R.; Cao, E.; Han, S.; Hu, L.; Quach, T.; Senyschyn, D.; Ferreira, V.I.; Lee, G.; Leong, N.; Sharma, G.; Lim, S.F.; Nowell, C.J.; Chen, Z.; von Andrian, U.H.; Bonner, D.; Mintern, J.D.; Simpson, J.S.; Trevaskis, N.L.; Porter, C.J.H. Targeted delivery of mycophenolic acid to the mesenteric lymph node using a triglyceride mimetic prodrug approach enhances gut-specific immunomodulation in mice. Journal of Controlled Release, 2021, 332, 636–651. doi: 10.1016/j.jconrel.2021.02.008
  186. Deirram, N.; Kermaniyan, S.S.; Johnston, A.P.R.; Such, G.K. Understanding the Polymer Rearrangement of pH-Responsive Nanoparticles. Australian Journal of Chemistry, 2021, 74(7), 514–521. doi: 10.1071/CH20331
  187. Best, Q.A.; Haack, R.A.; Swift, K.M.; Bax, B.M.; Tetin, S.Y.; Hershberger, S.J. A Rainbow of Acridinium Chemiluminescence. Luminescence, 2021, 36(4), 1097–1106. doi: 10.1002/bio.4038
  188. Nixon, B.; Anderson, A.L.; Bromfield, E.G.; Martin, J.H.; Cafe, S.L.; Skerrett-Byrne, D.A.; Dun, M.D.; Eamens, A.L.; De Iuliis, G.N.; Johnston, S.D. Post-testicular sperm maturation in the saltwater crocodile Crocodylus porosus: assessing the temporal acquisition of sperm motility. Reproduction, Fertility, and Development, 2021, 33(9), 530–539. doi: 10.1071/RD20204
  189. Fernández-Rico, C.; Urbach, J.S.; Dullens, R.P.A. Synthesis of Rough Colloidal SU-8 Rods and Bananas via Nanoprecipitation. Langmuir, 2021, 37(9), 2900–2906. doi: 10.1021/acs.langmuir.0c03361
  190. Lu, Z.; Zhang, Y.; Wang, Y.; Tan, G.-H.; Huang, F.-Y.; Cao, R.; He, N.; Zhang, L. A biotin-avidin-system-based virus-mimicking nanovaccine for tumor immunotherapy. Journal of Controlled Release, 2021, 332, 245–259. doi: 10.1016/j.jconrel.2021.02.029
  191. Berditchevskii, G.M.; Vasina, L.V.; Ageev, S.V.; Meshcheriakov, A.A.; Galkin, M.A.; Ishmukhametov, R.R.; Nashchekin, A.V.; Kirilenko, D.A.; Petrov, A.V.; Martynova, S.D.; Semenov, K.N.; Sharoyko, V.V. A comprehensive study of biocompatibility of detonation nanodiamonds. Journal of Molecular Liquids, 2021, 332, 115763. doi: 10.1016/j.molliq.2021.115763
  192. Yamansarov, E.Y.; Lopatukhina, E.V.; Evteev, S.A.; Skvortsov, D.A.; Lopukhov, A.V.; Kovalev, S.V.; Vaneev, A.N.; Shkil', D.O.; Akasov, R.A.; Lobov, A.N.; Naumenko, V.A.; Pavlova, E.N.; Ryabaya, O.O.; Burenina, O.Y.; Ivanenkov, Y.A.; Klyachko, N.L.; Erofeev, A.S.; Gorelkin, P.V.; Beloglazkina, E.K.; Majouga, A.G. Discovery of Bivalent GalNAc-Conjugated Betulin as a Potent ASGPR-Directed Agent against Hepatocellular Carcinoma. Bioconjugate Chemistry, 2021, 32(4), 763–781. doi: 10.1021/acs.bioconjchem.1c00042
  193. Xu, D.; Wang, Y. smFRET study of rRNA dimerization at the peptidyl transfer center. Biophysical Chemistry, 2021, 277, 106657. doi: 10.1016/j.bpc.2021.106657
  194. Thuenemann, E.C.; Le, D.H.T.; Lomonossoff, G.P.; Steinmetz, N.F. Bluetongue Virus Particles as Nanoreactors for Enzyme Delivery and Cancer Therapy. Molecular Pharmaceutics, 2021, 18(3), 1150–1156. doi: 10.1021/acs.molpharmaceut.0c01053
  195. Binkhathlan, Z.; Ali, R.; Qamar, W.; Al-Lawati, H.; Lavasanifar, A. Pharmacokinetic and Tissue Distribution of Orally Administered Cyclosporine A-Loaded poly(ethylene oxide)-block-Poly(ε-caprolactone) Micelles versus Sandimmune® in Rats. Pharmaceutical Research, 2021, 38(1), 51–65. doi: 10.1007/s11095-021-02990-5
  196. Bagheri, M.; Fens, M.H.; Kleijn, T.G.; Capomaccio, R.B.; Mehn, D.; Krawczyk, P.M.; Scutigliani, E.M.; Gurinov, A.; Baldus, M.; van Kronenburg, N.C.H.; Kok, R.J.; Heger, M.; van Nostrum, C.F.; Hennink, W.E. In Vitro and In Vivo Studies on HPMA-Based Polymeric Micelles Loaded with Curcumin. Molecular Pharmaceutics, 2021, 18(3), 1247–1263. doi: 10.1021/acs.molpharmaceut.0c01114
  197. Amar-Lewis, E.; Buaron, N.; Chintakunta, R.; Benafsha, C.; Goldbart, R.; Traitel, T.; Prasad, M.; Elkabets, M.; Kost, J. Quaternized Starch-Based Composite Nanoparticles for siRNA Delivery to Tumors. ACS Applied Nano Materials, 2021, 4(2), 2218–2229. doi: 10.1021/acsanm.1c00032
  198. Nam, S.H.; Jang, J.; Cheon, D.H.; Chong, S.-E.; Ahn, J.H.; Hyun, S.; Yu, J.; Lee, Y. pH-Activatable cell penetrating peptide dimers for potent delivery of anticancer drug to triple-negative breast cancer. Journal of Controlled Release, 2021, 330, 898–906. doi: 10.1016/j.jconrel.2020.10.063
  199. Shikov, A.E.; Malovichko, Y.V.; Lobov, A.A.; Belousova, M.E.; Nizhnikov, A.A.; Antonets, K.S. The Distribution of Several Genomic Virulence Determinants Does Not Corroborate the Established Serotyping Classification of Bacillus thuringiensis. International Journal of Molecular Sciences, 2021, 22(5), 2244. doi: 10.3390/ijms22052244
  200. Nomoto, T.; Yao, Y.; Inoue, Y.; Suzuki, M.; Kanamori, K.; Takemoto, H.; Matsui, M.; Tomoda, K.; Nishiyama, N. Fructose-functionalized polymers to enhance therapeutic potential of p-Boronophenylalanine for neutron capture therapy. Journal of Controlled Release, 2021, 332, 184–193. doi: 10.1016/j.jconrel.2021.02.021
  201. Bin Rashed, F.; Stoica, A.C.; MacDonald, D.; El-Saidi, H.; Ricardo, C.; Bhatt, B.; Moore, J.; Diaz-Dussan, D.; Ramamonjisoa, N.; Mowery, Y.; Damaraju, S.; Fahlman, R.; Kumar, P.; Weinfeld, M. Identification of proteins and cellular pathways targeted by 2-nitroimidazole hypoxic cytotoxins. Redox Biology, 2021, 41, 101905. doi: 10.1016/j.redox.2021.101905
  202. Suraweera, A.; Duijf, P.H.G.; Jekimovs, C.; Schrobback, K.; Liu, C.; Adams, M.N.; O'Byrne, K.J.; Richard, D.J. COMMD1, from the Repair of DNA Double Strand Breaks, to a Novel Anti-Cancer Therapeutic Target. Cancers, 2021, 13(4), 830. doi: 10.3390/cancers13040830
  203. Wang, Y.; Xu, X.; Zhao, X.; Yin, Z. Functionalized polymeric hybrid micelles as an efficient nanotheranostic agent for thrombus imaging and thrombolysis. Acta Biomaterialia, 2021, 122, 278–290. doi: 10.1016/j.actbio.2020.10.015
  204. Trac, N.; Chen, L.-Y.; Zhang, A.; Liao, C.-P.; Poon, C.; Wang, J.; Ando, Y.; Joo, J.; Garri, C.; Shen, K.; Kani, K.; Gross, M.E.; Chung, E.J. CCR2-targeted micelles for anti-cancer peptide delivery and immune stimulation. Journal of Controlled Release, 2021, 329, 614–623. doi: 10.1016/j.jconrel.2020.09.054
  205. Yang, Y.; Zhang, Q.; Zhang, J.; Chen, A.; Chen, Y.; Li, S.; Ye, M.; Xuan, X.; Li, X.; He, H.; Wu, J. Natural pollen extract for photothermal therapy. Materials & Design, 2021, 202, 109573. doi: 10.1016/j.matdes.2021.109573
  206. Mizuno, H.L.; Anraku, Y.; Sakuma, I.; Akagi, Y. Design of a Photocleavable Drug Binding Platform for a Novel Remotely Controllable Drug Coated Balloon. Journal of Drug Delivery Science and Technology, 2021, 62, 102375. doi: 10.1016/j.jddst.2021.102375
  207. Nguyen, H.T.; Phung, C.D.; Tran, T.H.; Pham, T.T.; Pham, L.M.; Nguyen, T.T.; Jeong, J.-H.; Choi, H.-G.; Ku, S.K.; Yong, C.S.; Kim, J.O. Manipulating immune system using nanoparticles for an effective cancer treatment: Combination of targeted therapy and checkpoint blockage miRNA. Journal of Controlled Release, 2021, 329, 524–537. doi: 10.1016/j.jconrel.2020.09.034
  208. Seneviratne, U.; Huang, Z.; Am Ende, C.W.; Butler, T.W.; Cleary, L.; Dresselhaus, E.; Evrard, E.; Fisher, E.L.; Green, M.E.; Helal, C.J.; Humphrey, J.M.; Lanyon, L.F.; Marconi, M.; Mukherjee, P.; Sciabola, S.; Steppan, C.M.; Sylvain, E.K.; Tuttle, J.B.; Verhoest, P.R.; Wager, T.T.; Xie, L.; Ramaswamy, G.; Johnson, D.S.; Pettersson, M. Photoaffinity Labeling and Quantitative Chemical Proteomics Identify LXRβ as the Functional Target of Enhancers of Astrocytic apoE. Cell Chemical Biology, 2021, 28(2), 148–157.e7. doi: 10.1016/j.chembiol.2020.09.002
  209. Emami, F.; Pathak, S.; Nguyen, T.T.; Shrestha, P.; Maharjan, S.; Kim, J.O.; Jeong, J.-H.; Yook, S. Photoimmunotherapy with cetuximab-conjugated gold nanorods reduces drug resistance in triple negative breast cancer spheroids with enhanced infiltration of tumor-associated macrophages. Journal of Controlled Release, 2021, 329, 645–664. doi: 10.1016/j.jconrel.2020.10.001
  210. Lapenta, F.; Aupič, J.; Vezzoli, M.; Strmšek, Ž.; Da Vela, S.; Svergun, D.I.; Carazo, J.M.; Melero, R.; Jerala, R. Self-assembly and regulation of protein cages from pre-organised coiled-coil modules. Nature Communications, 2021, 12, 939. doi: 10.1038/s41467-021-21184-6
  211. Aupič, J.; Strmšek, Ž.; Lapenta, F.; Pahovnik, D.; Pisanski, T.; Drobnak, I.; Ljubetič, A.; Jerala, R. Designed folding pathway of modular coiled-coil-based proteins. Nature Communications, 2021, 12, 940. doi: 10.1038/s41467-021-21185-5
  212. Gribanyov, D.; Zhdanov, G.; Olenin, A.; Lisichkin, G.; Gambaryan, A.; Kukushkin, V.; Zavyalova, E. SERS-Based Colloidal Aptasensors for Quantitative Determination of Influenza Virus. International Journal of Molecular Sciences, 2021, 22(4), 1842. doi: 10.3390/ijms22041842
  213. Hull, S.M.; Lindsay, C.D.; Brunel, L.G.; Shiwarski, D.J.; Tashman, J.W.; Roth, J.G.; Myung, D.; Feinberg, A.W.; Heilshorn, S.C. 3D Bioprinting using UNIversal Orthogonal Network (UNION) Bioinks. Advanced Functional Materials, 2021, 31(7), 2007983. doi: 10.1002/adfm.202007983
  214. Ji, M.-L.; Jiang, H.; Wu, F.; Geng, R.; Ya, L.K.; Lin, Y.C.; Xu, J.H.; Wu, X.T.; Lu, J. Precise targeting of miR-141/200c cluster in chondrocytes attenuates osteoarthritis development. Annals of the Rheumatic Diseases, 2021, 80(3), 356–366. doi: 10.1136/annrheumdis-2020-218469
  215. Petrov, R.A.; Mefedova, S.R.; Yamansarov, E.Y.; Maklakova, S.Y.; Grishin, D.A.; Lopatukhina, E.V.; Burenina, O.Y.; Lopukhov, A.V.; Kovalev, S.V.; Timchenko, Y.V.; Ondar, E.E.; Ivanenkov, Y.A.; Evteev, S.A.; Vaneev, A.N.; Timoshenko, R.V.; Klyachko, N.L.; Erofeev, A.S.; Gorelkin, P.V.; Beloglazkina, E.K.; Majouga, A.G. New Small-Molecule Glycoconjugates of Docetaxel and GalNAc for Targeted Delivery to Hepatocellular Carcinoma. Molecular Pharmaceutics, 2021, 18(1), 461–468. doi: 10.1021/acs.molpharmaceut.0c00980
  216. Fang, Y.; Coulter, J.A.; Wu, J.; Liu, L.; Li, X.; Dong, Y.; Ma, L.; Pu, Y.; Sun, B.; Niu, Z.; Jin, J.; Zhao, Y.; Mi, W.; Xu, Y.; Sun, W. Identification of differentially expressed genes involved in amino acid and lipid accumulation of winter turnip rape (Brassica rapa L.) in response to cold stress. PloS ONE, 2021, 16(2), e0245494. doi: 10.1371/journal.pone.0245494
  217. Van Lysebetten, D.; Malfanti, A.; Deswarte, K.; Koynov, K.; Golba, B.; Ye, T.; Zhong, Z.; Kasmi, S.; Lamoot, A.; Chen, Y.; Van Herck, S.; Lambrecht, B.N.; Sanders, Niek N.N.; Lienenklaus, S.; David, S.A.; Vicent, M.J.; De Koker, S.; De Geest, B.G. Lipid-Polyglutamate Nanoparticle Vaccine Platform. ACS Applied Materials & Interfaces, 2021, 13(5), 6011–6022. doi: 10.1021/acsami.0c20607
  218. Phung, C.D.; Tran, T.H.; Choi, J.-Y.; Jeong, J.-H.; Ku, S.K.; Yong, C.S.; Kim, J.O. Pre- and Post-Transcriptional Regulation of cFLIP for Effective Cancer Therapy Using pH-Ultrasensitive Nanoparticles. ACS Applied Materials & Interfaces, 2021, 13(5), 5999–6010. doi: 10.1021/acsami.0c20624
  219. De Luca, S.; Treny, J.; Chen, F.; Seal, P.; Stenzel, M.H.; Smith, S.C. Enhancing Cationic Drug Delivery with Polymeric Carriers: The Coulomb-pH Switch Approach. Advanced Theory and Simulations, 2021, 4(2), 2000247. doi: 10.1002/adts.202000247
  220. Abukar, T.; Rahmani, S.; Thompson, N.K.; Antonescu, C.N.; Wakarchuk, W.W. Development of BODIPY labelled sialic acids as sialyltransferase substrates for direct detection of terminal galactose on N- and O-linked glycans. Carbohydrate Research, 2021, 500, 108249. doi: 10.1016/j.carres.2021.108249
  221. Wang, K.; Kievit, F.M.; Chiarelli, P.A.; Stephen, Z.R.; Lin, G.; Silber, J.R.; Ellenbogen, R.G.; Zhang, M. siRNA Nanoparticle Suppresses Drug-Resistant Gene and Prolongs Survival in an Orthotopic Glioblastoma Xenograft Mouse Model. Advanced Functional Materials, 2021, 31(6), 2007166. doi: 10.1002/adfm.202007166
  222. González, L.F.; Acuña, E.; Arellano, G.; Morales, P.; Sotomayor, P.; Oyarzun-Ampuero, F.; Naves, R. Intranasal delivery of interferon-β-loaded nanoparticles induces control of neuroinflammation in a preclinical model of multiple sclerosis: A promising simple, effective, non-invasive, and low-cost therapy. Journal of Controlled Release, 2021, 331, 443–459. doi: 10.1016/j.jconrel.2020.11.019
  223. Serteyn, L.; Bosquee, E.; Delatour, A.; Rubio-Melendez, M.E.; Vega-Muñoz, K.V.; Ramirez, C.C.; Francis, F. Multi-approach comparative study of the two most prevalent genotypes of pea aphid Acyrthosiphon pisum (Hemiptera: Aphididae) in Chile. Entomological Science, 2021, 24(1), 55–67. doi: 10.1111/ens.12436
  224. Chudinov, A.V.; Vasiliskov, V.A.; Kuznetsova, V.E.; Lapa, S.A.; Kolganova, N.A.; Timofeev, E.N. Mononucleotide repeat expansions with non-natural polymerase substrates. Scientific Reports, 2021, 11, 2423. doi: 10.1038/s41598-021-82150-2
  225. Huo, S.; Zhao, P.; Shi, Z.; Zou, M.; Yang, X.; Warszawik, E.; Loznik, M.; Göstl, R.; Herrmann, A. Mechanochemical bond scission for the activation of drugs. Nature Chemistry, 2021, 13, 131–139. doi: 10.1038/s41557-020-00624-8
  226. Ford, C.A.; Spoonmore, T.J.; Gupta, M.K.; Duvall, C.L.; Guelcher, S.A.; Cassat, J.E. Diflunisal-loaded poly(propylene sulfide) nanoparticles decrease S. aureus-mediated bone destruction during osteomyelitis. Journal of Orthopaedic Research, 2021, 39(2), 426–437. doi: 10.1002/jor.24948
  227. Biosca, A.; Cabanach, P.; Abdulkarim, M.; Gumbleton, M.; Gómez-Canela, C.; Ramírez, M.; Bouzón-Arnáiz, I.; Avalos-Padilla, Y.; Borros, S.; Fernàndez-Busquets, X. Zwitterionic self-assembled nanoparticles as carriers for Plasmodium targeting in malaria oral treatment. Journal of Controlled Release, 2021, 331, 364–375. doi: 10.1016/j.jconrel.2021.01.028
  228. Si, Y.; Xu, Y.; Guan, J.; Chen, K.; Kim, S.; Yang, E.S.; Zhou, L.; Liu, X.M. Anti-EGFR antibody-drug conjugate for triple-negative breast cancer therapy. Engineering in Life Sciences, 2021, 21(1–2), 37–44. doi: 10.1002/elsc.202000027
  229. Shao, S.; Ortega-Rivera, O.A.; Ray, S.; Pokorski, J.K.; Steinmetz, N.F. A Scalable Manufacturing Approach to Single Dose Vaccination against HPV. Vaccines, 2021, 9(1), 66. doi: 10.3390/vaccines9010066
  230. Novoselova, M.V.; German, S.V.; Abakumova, T.O.; Perevoschikov, S.V.; Sergeeva, O.V.; Nesterchuk, M.V.; Efimova, O.I.; Petrov, K.S.; Chernyshev, V.S.; Zatsepin, T.S.; Gorin, D.A. Multifunctional nanostructured drug delivery carriers for cancer therapy: Multimodal imaging and ultrasound-induced drug release. Colloids and Surfaces B: Biointerfaces, 2021, 200, 111576. doi: 10.1016/j.colsurfb.2021.111576
  231. Jiang, H.; Cole, P.A. N-Terminal Protein Labeling with N-Hydroxysuccinimide Esters and Microscale Thermophoresis Measurements of Protein-Protein Interactions Using Labeled Protein. Current Protocols, 2021, 1, e14. doi: 10.1002/cpz1.14
  232. Zhang, Y.; Hughes, K.R.; Raghani, R.M.; Ma, J.; Orbach, S.; Jeruss, J.S.; Shea, L.D. Cargo-free immunomodulatory nanoparticles combined with anti-PD-1 antibody for treating metastatic breast cancer. Biomaterials, 2021, 269, 120666. doi: 10.1016/j.biomaterials.2021.120666
  233. Lim, S.; Kim, W.; Song, S.; Shim, M.K.; Yoon, H.Y.; Kim, B.-S.; Kwon, I.C.; Kim, K. Intracellular Uptake Mechanism of Bioorthogonally Conjugated Nanoparticles on Metabolically Engineered Mesenchymal Stem Cells. Bioconjugate Chemistry, 2021, 32(1), 199–214. doi: 10.1021/acs.bioconjchem.0c00640
  234. Lee, S.Y.; Yang, M.; Seo, J.-H.; Jeong, D.I.; Hwang, C.; Kim, H.-J.; Lee, J.; Lee, K.; Park, J.; Cho, H.-J. Serially pH-Modulated Hydrogels Based on Boronate Ester and Polydopamine Linkages for Local Cancer Therapy. ACS Applied Materials & Interfaces, 2021, 13(2), 2189–2203. doi: 10.1021/acsami.0c16199
  235. Gurevich, D.; Dor, S.; Erov, M.; Dan, Y.; Moy, J.C.; Mairesse, O.; Dafny-Yelin, M.; Adler-Abramovich, L.; Afriat-Jurnou, L. Directed Enzyme Evolution and Encapsulation in Peptide Nanospheres of Quorum Quenching Lactonase as an Antibacterial Treatment against Plant Pathogen. ACS Applied Materials & Interfaces, 2021, 13(2), 2179–2188. doi: 10.1021/acsami.0c15808
  236. Shen, J.Z.; Qiu, Z.; Wu, Q.; Finlay, D.; Garcia, G.; Sun, D.; Rantala, J.; Barshop, W.; Hope, J.L.; Gimple, R.C.; Sangfelt, O.; Bradley, L.M.; Wohlschlegel, J.; Rich, J.N.; Spruck, C. FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells. Cell, 2021, 184(2), 352–369.e23. doi: 10.1016/j.cell.2020.11.042
  237. Lyu, X.; Lei, K.-H.; Biak Sang, P.; Shiva, O.; Chastain, M.; Chi, P.; Chai, W. Human CST complex protects stalled replication forks by directly blocking MRE11 degradation of nascent-strand DNA. EMBO Journal, 2021, 40(2), e103654. doi: 10.15252/embj.2019103654
  238. Pham, L.M.; Kim, E.-C.; Ou, W.; Phung, C.D.; Nguyen, T.T.; Pham, T.T.; Poudel, K.; Gautam, M.; Nguyen, H.T.; Jeong, J.-H.; Yong, C.S.; Park, S.-Y.; Kim, J.-R.; Kim, J.O. Targeting and Clearance of Senescent Foamy Macrophages and Senescent Endothelial Cells by Antibody-Functionalized Mesoporous Silica Nanoparticles for Alleviating Aorta Atherosclerosis. Biomaterials, 2021, 269, 120677. doi: 10.1016/j.biomaterials.2021.120677
  239. Shapoval, O.; Oleksa, V.; Šlouf, M.; Lobaz, V.; Trhlíková, O.; Filipová, M.; Janoušková, O.; Engstová, H.; Pankrác, J.; Modrý, A.; Herynek, V.; Ježek, P.; Šefc, L.; Horák, D. Colloidally Stable P(DMA-AGME)-Ale-Coated Gd(Tb)F3:Tb3+(Gd3+),Yb3+,Nd3+ Nanoparticles as a Multimodal Contrast Agent for Down- and Upconversion Luminescence, Magnetic. Nanomaterials, 2021, 11(1), 230. doi: 10.3390/nano11010230
  240. González, M.I.; González-Arjona, M.; Santos-Coquillat, A.; Vaquero, J.; Vázquez-Ogando, E.; de Molina, A.; Peinado, H.; Desco, M.; Salinas, B. Covalently Labeled Fluorescent Exosomes for In Vitro and In Vivo Applications. Biomedicines, 2021, 9, 81. doi: 10.3390/biomedicines9010081
  241. Wang, Y.; Goun, A.; Laforge, F.; Quine, Z.; Rabitz, H. A key bidirectional switching issue in optogenetics emulated with laser dyes to illustrate its mitigation using nonlinear optical tools. Applied Physics Letters, 2021, 118(2), 024101. doi: 10.1063/5.0035183
  242. Guan, J.; Lu, C.; Jin, Q.; Lu, H.; Chen, X.; Tian, L.; Zhang, Y.; Ortega, J.; Zhang, J.; Siteni, S.; Chen, M.; Gu, L.; Shay, J.W.; Davis, A.J.; Chen, Z.J.; Fu, Y.-X.; Li, G.-M. MLH1 Deficiency-Triggered DNA Hyperexcision by Exonuclease 1 Activates the cGAS-STING Pathway. Cancer Cell, 2021, 39(1), 109–121.e5. doi: 10.1016/j.ccell.2020.11.004
  243. Lu, C.; Guan, J.; Lu, S.; Jin, Q.; Rousseau, B.; Lu, T.; Stephens, D.; Zhang, H.; Zhu, J.; Yang, M.; Ren, Z.; Liang, Y.; Liu, Z.; Han, C.; Liu, L.; Cao, X.; Zhang, A.; Qiao, J.; Batten, K.; Chen, M.; Castrillon, D.H.; Wang, T.; Li, B.; Diaz, L.A.; Li, G.-M.; Fu, Y.-X. DNA Sensing in Mismatch Repair-Deficient Tumor Cells Is Essential for Anti-tumor Immunity. Cancer Cell, 2021, 39(1), 96–108.e6. doi: 10.1016/j.ccell.2020.11.006
  244. Irwin, N.A.T.; Pittis, A.A.; Mathur, V.; Howe, L.J.; Keeling, P.J.; Lynn, D.H.; Bourland, W.A. The Function and Evolution of Motile DNA Replication Systems in Ciliates. Current Biology, 2021, 31(1), 66–76.e6. doi: 10.1016/j.cub.2020.09.077
  245. Bos, I.; Timmerman, M.; Sprakel, J. FRET-Based Determination of the Exchange Dynamics of Complex Coacervate Core Micelles. Macromolecules, 2021, 54(1), 398–411. doi: 10.1021/acs.macromol.0c02387
  246. Zeng, Q.; Deng, H.; Li, Y.; Fan, T.; Liu, Y.; Tang, S.; Wei, W.; Liu, X.; Guo, X.; Jiang, J.; Wang, Y.; Song, D. Berberine Directly Targets the NEK7 Protein to Block the NEK7–NLRP3 Interaction and Exert Anti-inflammatory Activity. Journal of Medicinal Chemistry, 2021, 64(1), 768–781. doi: 10.1021/acs.jmedchem.0c01743
  247. Ridolfo, R.; Tavakoli, S.; Junnuthula, V.; Williams, D.S.; Urtti, A.; van Hest, J.C.M. Exploring the impact of morphology on the properties of biodegradable nanoparticles and their diffusion in complex biological medium. Biomacromolecules, 2021, 22(1), 126–133. doi: 10.1021/acs.biomac.0c00726
  248. Nagai, H.; Tatara, H.; Tanaka-Furuhashi, K.; Kurata, S.; Yano, T. Homeostatic Regulation of ROS-Triggered Hippo-Yki Pathway via Autophagic Clearance of Ref(2)P/p62 in the Drosophila Intestine. Developmental Cell, 2021, 56(1), 81--94.e10. doi: 10.1016/j.devcel.2020.12.007
  249. Gueiderikh, A.; Maczkowiak-Chartois, F.; Rouvet, G.; Souquère-Besse, S.; Apcher, S.; Diaz, J.-J.; Rosselli, F. Fanconi anemia A protein participates in nucleolar homeostasis maintenance and ribosome biogenesis. Science Advances, 2021, 7(1), eabb5414. doi: 10.1126/sciadv.abb5414
  250. Conner, J.W.; Poole, D.P.; Jörg, M.; Veldhuis, N.A. New small molecule fluorescent probes for G protein-coupled receptors: valuable tools for drug discovery. Future Medicinal Chemistry, 2021, 13(1), 63–90. doi: 10.4155/fmc-2019-0327
  251. Park, Y.I.; Kwon, S.-H.; Lee, G.; Motoyama, K.; Kim, M.W.; Lin, M.; Niidome, T.; Choi, J.H.; Lee, R. pH-sensitive multi-drug liposomes targeting folate receptor β for efficient treatment of non-small cell lung cancer. Journal of Controlled Release, 2021, 330, 1–14. doi: 10.1016/j.jconrel.2020.12.011
  252. Novopashina, D.S.; Vorobyeva, M.A.; Lomzov, A.A.; Silnikov, V.N.; Venyaminova, A.G. Terminal Mono- and Bis-Conjugates of Oligonucleotides with Closo-Dodecaborate: Synthesis and Physico-Chemical Properties. International Journal of Molecular Sciences, 2021, 22(1), 182. doi: 10.3390/ijms22010182
  253. Morozov, V.N.; Kolyvanova, M.A.; Dement'eva, O.V.; Rudoy, V.M.; Kuzmin, V.A. Comparison of quenching efficacy of SYBR green I and picoGreen fluorescence by ultrasmall gold nanoparticles in isotropic and liquid-crystalline DNA systems. Journal of Molecular Liquids, 2021, 321, 114751. doi: 10.1016/j.molliq.2020.114751
  254. Anson, F.; Kanjilal, P.; Thayumanavan, S.; Hardy, J.A. Tracking Exogenous Intracellular Casp-3 Using Split GFP. Protein Science, 2021, 30(2), 366–380. doi: 10.1002/pro.3992
  255. DuRoss, A.N.; Landry, M.R.; Thomas, C.R.; Neufeld, M.J.; Sun, C. Fucoidan-coated nanoparticles target radiation-induced P-selectin to enhance chemoradiotherapy in murine colorectal cancer. Cancer Letters, 2021, 500, 208–219. doi: 10.1016/j.canlet.2020.11.021
  256. Martins dos Santos, A.; Bagliotti Meneguin, A.; Taslima Akhter, D.; Fletcher, N.; Houston, Z.H.; Bell, C.; Thurecht, K.J.; Palmira Daflon Gremião, M. Understanding the role of colon-specific microparticles based on retrograded starch/pectin in the delivery of chitosan nanoparticles along the gastrointestinal tract. European Journal of Pharmaceutics and Biopharmaceutics, 2021, 158, 371–378. doi: 10.1016/j.ejpb.2020.12.004
  257. Chetverikov, P.E.; Craemer, C.; Cvrković, T.; Klimov, P.B.; Petanović, R.U.; Romanovich, A.E.; Sukhareva, S.I.; Zukoff, S.N.; Bolton, S.; Amrine, J. Molecular phylogeny of the phytoparasitic mite family Phytoptidae (Acariformes: Eriophyoidea) identified the female genitalic anatomy as a major macroevolutionary factor and revealed multiple origins of gall induction. Experimental & Applied Acarology, 2021, 83(1), 31–68. doi: 10.1007/s10493-020-00571-6
  258. Nechaeva, N.L.; Sorokina, O.N.; Konstantinova, T.S.; Vasilyeva, A.D.; Yurina, L.V.; Byzova, N.A.; Bugrova, A.E.; Yanovich, S.V.; Eremenko, A.V.; Kurochkin, I.N. Simultaneous express immunoassay of multiple cardiac biomarkers with an automatic platform in human plasma. Talanta, 2021, 224, 121860. doi: 10.1016/j.talanta.2020.121860
  259. Thauvin, C.; Maudens, P.; Allémann, E. Microwave-assisted synthesis of self-assembling bi-functionalizable amphiphilic diblock copolymers. Journal of Drug Delivery Science and Technology, 2021, 61, 102255. doi: 10.1016/j.jddst.2020.102255
  260. Prikhozhdenko, E.S.; Gusliakova, O.I.; Kulikov, O.A.; Mayorova, O.A.; Shushunova, N.A.; Abdurashitov, A.S.; Bratashov, D.N.; Pyataev, N.A.; Tuchin, V.V.; Gorin, D.A.; Sukhorukov, G.B.; Sindeeva, O.A. Target delivery of drug carriers in mice kidney glomeruli via renal artery. Balance between efficiency and safety. Journal of Controlled Release, 2021, 329, 175–190. doi: 10.1016/j.jconrel.2020.11.051
  261. Ye, R.; Xu, H.; Gu, J.; Chen, H. Bioinspired synthesis of protein-posnjakite organic-inorganic nanobiohybrid for biosensing applications. Analytica Chimica Acta, 2021, 1143, 31–36. doi: 10.1016/j.aca.2020.11.026
  262. Merlo, R.; Caprioglio, D.; Cillo, M.; Valenti, A.; Mattossovich, R.; Morrone, C.; Massarotti, A.; Rossi, F.; Miggiano, R.; Leonardi, A.; Minassi, A.; Perugino, G. The SNAP-tag technology revised: an effective chemo-enzymatic approach by using a universal azide-based substrate. Journal of Enzyme Inhibition and Medicinal Chemistry, 2021, 36(1), 85–97. doi: 10.1080/14756366.2020.1841182
  263. Zhong, Z.; Deng, X.; Wang, P.; Yu, C.; Kiratitanaporn, W.; Wu, X.; Schimelman, J.; Tang, M.; Balayan, A.; Yao, E.; Tian, J.; Chen, L.; Zhang, K.; Chen, S. Rapid bioprinting of conjunctival stem cell micro-constructs for subconjunctival ocular injection. Biomaterials, 2021, 267, 120462. doi: 10.1016/j.biomaterials.2020.120462
  264. Janczewska, M.; Szkop, M.; Pikus, G.; Kopyra, K.; Świątkowska, A.; Brygoła, K.; Karczmarczyk, U.; Walczak, J.; Żuk, M.T.; Duszak, J.; Ciach, T. PSMA targeted conjugates based on dextran. Applied Radiation and Isotopes, 2021, 167, 109439. doi: 10.1016/j.apradiso.2020.109439
  265. Cuccaro, A.; De Marchi, L.; Oliva, M.; Sanches, M.V.; Freitas, R.; Casu, V.; Monni, G.; Miragliotta, V.; Pretti, C. Sperm quality assessment in Ficopomatus enigmaticus (Fauvel, 1923): Effects of selected organic and inorganic chemicals across salinity levels. Ecotoxicology and Environmental Safety, 2021, 207, 111219. doi: 10.1016/j.ecoenv.2020.111219
  266. Fornasier, M.; Porcheddu, A.; Casu, A.; Raghavan, S.R.; Jönsson, P.; Schillén, K.; Murgia, S. Surface-modified nanoerythrosomes for potential optical imaging diagnostics. Journal of Colloid and Interface Science, 2021, 582, 246–253. doi: 10.1016/j.jcis.2020.08.032
  267. Yao, J.; Huang, X.; Ren, J. In Situ Determination of Secretory Kinase Fam20C from Living Cells Using Fluorescence Correlation Spectroscopy. Talanta, 2021, 232, 122473. doi: 10.1016/j.talanta.2021.122473
  268. Sharoyko, V. V.; Iamalova, N. R.; Ageev, S. V.; Meshcheriakov, A. A.; Iurev, G. O.; Petrov, A. V.; Nerukh, D. A.; Farafonov, V. S.; Vasina, L. V.; Penkova, A. V.; Semenov, K. N. In Vitro and In Silico Investigation of Water-Soluble Fullerenol C60(OH)24: Bioactivity and Biocompatibility. J. Phys. Chem. B, 2021, 125(32), 9197–9212. doi: 10.1021/acs.jpcb.1c03332
  269. Pishesha, N.; Harmand, T.; Smeding, L. Y.; Ma, W.; Ludwig, L. S.; Janssen, R.; Islam, A.; Xie, Y. J.; Fang, T.; McCaul, N.; Pinney, W.; Sugito, H. R.; Rossotti, M. A.; Gonzalez-Sapienza, G.; Ploegh, H. L. Induction of Antigen-Specific Tolerance by Nanobody–Antigen Adducts That Target Class-II Major Histocompatibility Complexes. Nat Biomed Eng, 2021, 5(11), 1389–1401. doi: 10.1038/s41551-021-00738-5
  270. Sakhabutdinova, A. R.; Kamalov, M. I.; Salakhieva, D. V.; Mavzyutov, A. R.; Garafutdinov, R. R. Inhibition of Nonspecific Polymerase Activity Using Poly(Aspartic) Acid as a Model Anionic Polyelectrolyte. Analytical Biochemistry, 2021, 628, 114267. doi: 10.1016/j.ab.2021.114267
  271. Bayin, N. S.; Mizrak, D.; Stephen, D. N.; Lao, Z.; Sims, P. A.; Joyner, A. L. Injury-Induced ASCL1 Expression Orchestrates a Transitory Cell State Required for Repair of the Neonatal Cerebellum. Sci. Adv., 2021, 7(50), eabj1598. doi: 10.1126/sciadv.abj1598
  272. Junnuthula, V.; Sadeghi Boroujeni, A.; Cao, S.; Tavakoli, S.; Ridolfo, R.; Toropainen, E.; Ruponen, M.; van Hest, J. C. M.; Urtti, A. Intravitreal Polymeric Nanocarriers with Long Ocular Retention and Targeted Delivery to the Retina and Optic Nerve Head Region. Pharmaceutics, 2021, 13(4), 445. doi: 10.3390/pharmaceutics13040445.
  273. Kang, Y.; Flores, L.; Ngai, H. W.; Cornejo, Y. R.; Haber, T.; McDonald, M.; Moreira, D. F.; Gonzaga, J. M.; Abidi, W.; Zhang, Y.; Hammad, M.; Kortylewski, M.; Aboody, K. S.; Berlin, J. M. Large, Anionic Liposomes Enable Targeted Intraperitoneal Delivery of a TLR 7/8 Agonist To Repolarize Ovarian Tumors’ Microenvironment. Bioconjugate Chem., 2021, 32(8), 1581–1592. doi: 10.1021/acs.bioconjchem.1c00139
  274. Ganguly, S.; Neelam; Grinberg, I.; Margel, S. Layer by Layer Controlled Synthesis at Room Temperature of Tri-Modal (MRI, Fluorescence and CT) Core/Shell Superparamagnetic IO/Human Serum Albumin Nanoparticles for Diagnostic Applications. Polymers for Advanced Technologies, 2021, 32(10), 3909–3921. doi: 10.1002/pat.5344
  275. Rapoport, E. M.; Khasbiullina, N. R.; Komarova, V. A.; Ryzhov, I. M.; Gorbatch, M. M.; Tuzikov, A. B.; Khaidukov, S. V.; Popova, I. S.; Korchagina, E. Y.; Henry, S. M.; Bovin, N. V. Localization of Synthetic Glycolipids in the Cell and the Dynamics of Their Insertion/Loss. Biochimica et Biophysica Acta (BBA) - Biomembranes, 2021, 1863(9), м. doi: 10.1016/j.bbamem.2021.183645
  276. Nikitin, A. A.; Yurenya, A. Y.; Zatsepin, T. S.; Aparin, I. O.; Chekhonin, V. P.; Majouga, A. G.; Farle, M.; Wiedwald, U.; Abakumov, M. A. Magnetic Nanoparticles as a Tool for Remote DNA Manipulations at a Single-Molecule Level. ACS Appl. Mater. Interfaces, 2021, 13(12), 14458–14469. doi: 10.1021/acsami.0c21002
  277. Sim, T.; Choi, B.; Kwon, S. W.; Kim, K.-S.; Choi, H.; Ross, A.; Kim, D.-H. Magneto-Activation and Magnetic Resonance Imaging of Natural Killer Cells Labeled with Magnetic Nanocomplexes for the Treatment of Solid Tumors. ACS Nano, 2021, 15(8), 12780–12793. doi: 10.1021/acsnano.1c01889
  278. Xu, J.; Zhao, L.; Peng, S.; Chu, H.; Liang, R.; Tian, M.; Connell, P. P.; Li, G.; Chen, C.; Wang, H.-W. Mechanisms of Distinctive Mismatch Tolerance between Rad51 and Dmc1 in Homologous Recombination. Nucleic Acids Research, 2021, 49(22), 13135–13149. doi: 10.1093/nar/gkab1141
  279. Arduino, I.; Liu, Z.; Iacobazzi, R. M.; Lopedota, A. A.; Lopalco, A.; Cutrignelli, A.; Laquintana, V.; Porcelli, L.; Azzariti, A.; Franco, M.; Santos, H. A.; Denora, N. Microfluidic Preparation and in Vitro Evaluation of IRGD-Functionalized Solid Lipid Nanoparticles for Targeted Delivery of Paclitaxel to Tumor Cells. International Journal of Pharmaceutics, 2021, 610, 121246. doi: 10.1016/j.ijpharm.2021.121246
  280. Saouaf, O. M.; Roth, G. A.; Ou, B. S.; Smith, A. A. A.; Yu, A. C.; Gale, E. C.; Grosskopf, A. K.; Picece, V. C. T. M.; Appel, E. A. Modulation of Injectable Hydrogel Properties for Slow Co-Delivery of Influenza Subunit Vaccine Components Enhance the Potency of Humoral Immunity. Journal of Biomedical Materials Research Part A, 2021, 109(11), 2173–2186. doi: 10.1002/jbm.a.37203
  281. Liu, L.; Huang, K.; Li, W.; Qiu, R.; Fang, Y.; Huang, Y.; Zhao, S.; Lv, H.; Zhang, K.; Shan, H.; Li, Y. Molecular Imaging of Collagen Destruction of the Spine. ACS Nano, 2021, 15(12), 19138–19149. doi: 10.1021/acsnano.1c07112
  282. Saidi, A.; Wartenberg, M.; Madinier, J.-B.; Ilango, G.; Seren, S.; Korkmaz, B.; Lecaille, F.; Aucagne, V.; Lalmanach, G. Monitoring Human Neutrophil Activation by a Proteinase 3 Near-Infrared Fluorescence Substrate-Based Probe. Bioconjugate Chem., 2021, 32(8), 1782–1790. doi: 10.1021/acs.bioconjchem.1c00267
  283. Pilipenko, I.; Korzhikov-Vlakh, V.; Valtari, A.; Anufrikov, Y.; Kalinin, S.; Ruponen, M.; Krasavin, M.; Urtti, A.; Tennikova, T. Mucoadhesive Properties of Nanogels Based on Stimuli-Sensitive Glycosaminoglycan-Graft-PNIPAAm Copolymers. International Journal of Biological Macromolecules, 2021, 186, 864–872. doi: 10.1016/j.ijbiomac.2021.07.070
  284. Cursi, L.; Vercellino, S.; M. McCafferty, M.; Sheridan, E.; Petseva, V.; Adumeau, L.; A. Dawson, K. Multifunctional Superparamagnetic Nanoparticles with a Fluorescent Silica Shell for the in Vitro Study of Bio-Nano Interactions at the Subcellular Scale. Nanoscale, 2021, 13(38), 16324–16338. doi: 10.1039/D1NR04582B
  285. Gvozdev, D. A.; Ramonova, А. А.; Slonimskiy, Y. B.; Gudkova, V. R.; Nikelshparg, E. I.; Moisenovich, A. М.; Moisenovich, М. М.; Zaitsev, A. V.; Olshevskaya, V. A.; Paschenko, V. Z.; Maksimov, Е. G. Nanodiamonds as a Platform for Targeted Delivery of Chlorin-Based Photosensitizers to Cancer Cells. Diamond and Related Materials, 2021, 120, 108676. doi: 10.1016/j.diamond.2021.108676
  286. Zhao, P.; Xia, X.; Xu, X.; Leung, K. K. C.; Rai, A.; Deng, Y.; Yang, B.; Lai, H.; Peng, X.; Shi, P.; Zhang, H.; Chiu, P. W. Y.; Bian, L. Nanoparticle-Assembled Bioadhesive Coacervate Coating with Prolonged Gastrointestinal Retention for Inflammatory Bowel Disease Therapy. Nat Commun, 2021, 12(1), 7162. doi: 10.1038/s41467-021-27463-6
  287. Kwon, S. P.; Hwang, B.-H.; Park, E.-H.; Kim, H. Y.; Lee, J.-R.; Kang, M.; Song, S. Y.; Jung, M.; Sohn, H. S.; Kim, E.; Kim, C. W.; Lee, K. Y.; Oh, G. C.; Choo, E.; Lim, S.; Chung, Y.; Chang, K.; Kim, B.-S. Nanoparticle-Mediated Blocking of Excessive Inflammation for Prevention of Heart Failure Following Myocardial Infarction. Small, 2021, 17(32), 2101207. doi: 10.1002/smll.202101207
  288. Choi, H.; Kwon, M.; Choi, H. E.; Hahn, S. K.; Kim, K. S. Non-Invasive Topical Drug-Delivery System Using Hyaluronate Nanogels Crosslinked via Click Chemistry. Materials, 2021, 14(6), 1504. doi: 10.3390/ma14061504
  289. Yu, J. H.; Steinberg, I.; Davis, R. M.; Malkovskiy, A. V.; Zlitni, A.; Radzyminski, R. K.; Jung, K. O.; Chung, D. T.; Curet, L. D.; D’Souza, A. L.; Chang, E.; Rosenberg, J.; Campbell, J.; Frostig, H.; Park, S.; Pratx, G.; Levin, C.; Gambhir, S. S. Noninvasive and Highly Multiplexed Five-Color Tumor Imaging of Multicore Near-Infrared Resonant Surface-Enhanced Raman Nanoparticles In Vivo. ACS Nano, 2021, 15(12), 19956–19969. doi: 10.1021/acsnano.1c07470
  290. van der Post, S.; Birchenough, G. M. H.; Held, J. M. NOX1-Dependent Redox Signaling Potentiates Colonic Stem Cell Proliferation to Adapt to the Intestinal Microbiota by Linking EGFR and TLR Activation. Cell Reports, 2021, 35(1), 108949. doi: 10.1016/j.celrep.2021.108949
  291. Ticho, A. L.; Calzadilla, N.; Malhotra, P.; Lee, H.; Anbazhagan, A. N.; Saksena, S.; Dudeja, P. K.; Lee, D.; Gill, R. K.; Alrefai, W. A. NPC1L1-Dependent Transport of 27-Alkyne Cholesterol in Intestinal Epithelial Cells. American Journal of Physiology-Cell Physiology, 2021, 320(5), C916–C925. doi: 10.1152/ajpcell.00062.2021
  292. DeJulius, C. R.; Dollinger, B. R.; Kavanaugh, T. E.; Dailing, E.; Yu, F.; Gulati, S.; Miskalis, A.; Zhang, C.; Uddin, J.; Dikalov, S.; Duvall, C. L. Optimizing an Antioxidant TEMPO Copolymer for Reactive Oxygen Species Scavenging and Anti-Inflammatory Effects in Vivo. Bioconjugate Chem, 2021, 32(5), 928–941. doi: 10.1021/acs.bioconjchem.1c00081
  293. Abdurashitov, A. S.; Prikhozhdenko, E. S.; Mayorova, O. A.; Plastun, V. O.; Gusliakova, O. I.; Shushunova, N. A.; Kulikov, O. A.; Tuchin, V. V.; Sukhorukov, G. B.; Sindeeva, O. A. Optical Coherence Microangiography of the Mouse Kidney for Diagnosis of Circulatory Disorders. Biomed. Opt. Express, BOE, 2021, 12(7), 4467–4477. doi: 10.1364/BOE.430393
  294. Poudel, S.; Napit, P. R.; Briski, K. P.; Mattheolabakis, G. Oral Delivery of Nucleic Acids with Passive and Active Targeting to the Intestinal Tissue Using Polymer-Based Nanocarriers. Pharmaceutics, 2021, 13(7), 1075. doi: 10.3390/pharmaceutics13071075
  295. Lee, S.; Kim, H. J.; Park, J.-I.; Cho, H. B.; Park, J. S.; Park, K.-H. Organelle Targeting Using a Fluorescent Probe That Selectively Penetrates the Zona Pellucida. International Journal of Pharmaceutics, 2021, 610, 121282. doi: 10.1016/j.ijpharm.2021.121282
  296. Talamini, L.; Picchetti, P.; Ferreira, L. M.; Sitia, G.; Russo, L.; Violatto, M. B.; Travaglini, L.; Fernandez Alarcon, J.; Righelli, L.; Bigini, P.; De Cola, L. Organosilica Cages Target Hepatic Sinusoidal Endothelial Cells Avoiding Macrophage Filtering. ACS Nano, 2021, 15(6), 9701–9716.. doi: 10.1021/acsnano.1c00316
  297. Chapman, D. V.; Hinckley, J. A.; Erstling, J. A.; Estroff, L. A.; Wiesner, U. B. Orthogonal Nanoprobes Enabling Two-Color Optical Super-Resolution Microscopy Imaging of the Two Domains of Diblock Copolymer Thin Film Nanocomposites. Chem. Mater., 2021, 33(13), 5156–5167. doi: 10.1021/acs.chemmater.1c01204
  298. Tsao, W.; Buj, R.; Aird, K. M.; Sidorova, J. M.; Eckert, K. A. Overexpression of Oncogenic H-Ras in HTERT-Immortalized and SV40-Transformed Human Cells Targets Replicative and Specialized DNA Polymerases for Depletion. PLOS ONE, 2021, 16(5), e0251188. doi: 10.1371/journal.pone.0251188
  299. Guarin, M.; Ny, A.; De Croze, N.; Maes, J.; Léonard, M.; Annaert, P.; de Witte, P. A. M. Pharmacokinetics in Zebrafish Embryos (ZFE) Following Immersion and Intrayolk Administration: A Fluorescence-Based Analysis. Pharmaceuticals, 2021, 14(6), 576. doi: 10.3390/ph14060576
  300. Cao, S.; Shao, J.; Wu, H.; Song, S.; De Martino, M. T.; Pijpers, I. A. B.; Friedrich, H.; Abdelmohsen, L. K. E. A.; Williams, D. S.; van Hest, J. C. M. Photoactivated Nanomotors via Aggregation Induced Emission for Enhanced Phototherapy. Nat Commun, 2021, 12(1), 2077. doi: 10.1038/s41467-021-22279-w
  301. van Vliet, T.; Varela-Eirin, M.; Wang, B.; Borghesan, M.; Brandenburg, S. M.; Franzin, R.; Evangelou, K.; Seelen, M.; Gorgoulis, V.; Demaria, M. Physiological Hypoxia Restrains the Senescence-Associated Secretory Phenotype via AMPK-Mediated MTOR Suppression. Molecular Cell, 2021, 81(9), 2041-2052.e6. doi: 10.1016/j.molcel.2021.03.018
  302. Tong, O.; Duette, G.; O’Neil, T. R.; Royle, C. M.; Rana, H.; Johnson, B.; Popovic, N.; Dervish, S.; Brouwer, M. A. E.; Baharlou, H.; Patrick, E.; Ctercteko, G.; Palmer, S.; Lee, E.; Hunter, E.; Harman, A. N.; Cunningham, A. L.; Nasr, N. Plasmacytoid Dendritic Cells Have Divergent Effects on HIV Infection of Initial Target Cells and Induce a Pro-Retention Phenotype. PLOS Pathogens, 2021, 17(4), e1009522. doi: 10.1371/journal.ppat.1009522
  303. Hang, Y.; Tang, S.; Tang, W.; Větvička, D.; Zhang, C.; Xie, Y.; Yu, F.; Yu, A.; Sil, D.; Li, J.; Singh, R. K.; Oupický, D. Polycation Fluorination Improves Intraperitoneal SiRNA Delivery in Metastatic Pancreatic Cancer. Journal of Controlled Release, 2021, 333, 139–150. doi: 10.1016/j.jconrel.2021.03.028
  304. Qi, Y.; Li, J.; Nie, Q.; Gao, M.; Yang, Q.; Li, Z.; Li, Q.; Han, S.; Ding, J.; Li, Y.; Zhang, J. Polyphenol-Assisted Facile Assembly of Bioactive Nanoparticles for Targeted Therapy of Heart Diseases. Biomaterials, 2021, 275, 120952. doi: 10.1016/j.biomaterials.2021.120952
  305. Kim, J.; Kim, J.-M.; Ha, M.; Oh, J.-W.; Nam, J.-M. Polysorbate- and DNA-Mediated Synthesis and Strong, Stable, and Tunable Near-Infrared Photoluminescence of Plasmonic Long-Body Nanosnowmen. ACS Nano, 2021, 15(12), 19853–19863. doi: 10.1021/acsnano.1c07319
  306. Cresti, J. R.; Manfredonia, A. J.; Bragança, C. E.; Boscia, J. A.; Hurley, C. M.; Cundiff, M. D.; Kraut, D. A. Proteasomal Conformation Controls Unfolding Ability. Proceedings of the National Academy of Sciences, 2021, 118(25), e2101004118. doi: 10.1073/pnas.2101004118
  307. Niu, X.; Sun, R.; Chen, Z.; Yao, Y.; Zuo, X.; Chen, C.; Fang, X. Pseudoknot Length Modulates the Folding, Conformational Dynamics, and Robustness of Xrn1 Resistance of Flaviviral XrRNAs. Nat Commun, 2021, 12(1), 6417. doi: 10.1038/s41467-021-26616-x
  308. Kicková, E.; Salmaso, S.; Mastrotto, F.; Caliceti, P.; Urtti, A. Pullulan Based Bioconjugates for Ocular Dexamethasone Delivery. Pharmaceutics, 2021, 13(6), 791. doi: 10.3390/pharmaceutics13060791
  309. Yin, Q.; Pan, A.; Chen, B.; Wang, Z.; Tang, M.; Yan, Y.; Wang, Y.; Xia, H.; Chen, W.; Du, H.; Chen, M.; Fu, C.; Wang, Y.; Yuan, X.; Lu, Z.; Zhang, Q.; Wang, Y. Quantitative Imaging of Intracellular Nanoparticle Exposure Enables Prediction of Nanotherapeutic Efficacy. Nat Commun, 2021, 12(1), 2385. doi: 10.1038/s41467-021-22678-z
  310. Li, H.; Li, X.; Chen, L.; Li, B.; Dong, H.; Liu, H.; Yang, X.; Ueda, H.; Dong, J. Quench-Release-Based Fluorescent Immunosensor for the Rapid Detection of Tumor Necrosis Factor α. ACS Omega, 2021, 6(46), 31009–31016. doi: 10.1021/acsomega.1c03941
  311. Shih, T.-Y.; Najibi, A. J.; Bartlett, A. L.; Li, A. W.; Mooney, D. J. Ultrasound-Triggered Release Reveals Optimal Timing of CpG-ODN Delivery from a Cryogel Cancer Vaccine. Biomaterials, 2021, 279, 121240. doi: 10.1016/j.biomaterials.2021.121240
  312. Usuelli, M.; Meyer, T.; Mezzenga, R.; Mitsi, M. VEGF and VEGFR2 Bind to Similar PH-Sensitive Sites on Fibronectin, Exposed by Heparin-Mediated Conformational Changes. Journal of Biological Chemistry, 2021, 296, 100584. doi: 10.1016/j.jbc.2021.100584
  313. Rickert-Zacharias, V.; Schultz, M.; Mall, M. A.; Schultz, C. Visualization of Ectopic Serine Protease Activity by Förster Resonance Energy Transfer-Based Reporters. ACS Chem. Biol., 2021, 16(11), 2174–2184.. doi: 10.1021/acschembio.1c00168
  314. Zhang, Y.; Yin, Y.; Zhang, W.; Li, H.; Wang, T.; Yin, H.; Sun, L.; Su, C.; Zhang, K.; Xu, H. Reactive Oxygen Species Scavenging and Inflammation Mitigation Enabled by Biomimetic Prussian Blue Analogues Boycott Atherosclerosis. Journal of Nanobiotechnology, 2021, 19(1), 161. doi: 10.1186/s12951-021-00897-2
  315. Ng, S. C.; Güttler, T.; Görlich, D. Recapitulation of Selective Nuclear Import and Export with a Perfectly Repeated 12mer GLFG Peptide. Nat Commun, 2021, 12(1), 4047. doi: 10.1038/s41467-021-24292-5
  316. Mattila, J. T.; Beaino, W.; White, A. G.; Nyiranshuti, L.; Maiello, P.; Tomko, J.; Frye, L. J.; Fillmore, D.; Scanga, C. A.; Lin, P. L.; Flynn, J. L.; Anderson, C. J. Retention of 64Cu-FLFLF, a Formyl Peptide Receptor 1-Specific PET Probe, Correlates with Macrophage and Neutrophil Abundance in Lung Granulomas from Cynomolgus Macaques. ACS Infect. Dis., 2021, 7(8), 2264–2276. doi: 10.1021/acsinfecdis.0c00826
  317. Kotlar, R. M.; Jones, N. D.; Senavirathne, G.; Gardner, A. M.; Messer, R. K.; Tan, Y. Y.; Rabe, A. J.; Fishel, R.; Yoder, K. E. Retroviral Prototype Foamy Virus Intasome Binding to a Nucleosome Target Does Not Determine Integration Efficiency. Journal of Biological Chemistry, 2021, 296, 100550. doi: 10.1016/j.jbc.2021.100550
  318. Rex, R.; Siddhanta, S.; Barman, I. Role of Aqueous-Phase Calcination in Synthesis of Ultra-Stable Dye-Embedded Fluorescent Nanoparticles for Cellular Probing. Appl Spectrosc, 2021, 75(8), 1012–1021. doi: 10.1177/00037028211027597
  319. Diaz-Salmeron, R.; Michel, J.-P.; Hadji, H.; Gout, E.; Vivès, Romain. R.; Ponchel, G.; Bouchemal, K. Role of the Interactions of Soft Hyaluronan Nanomaterials with CD44 and Supported Bilayer Membranes in the Cellular Uptake. Colloids and Surfaces B: Biointerfaces, 2021, 205, 111916. doi: 10.1016/j.colsurfb.2021.111916
  320. Goryunova, M. S.; Arzhanik, V. K.; Zavriev, S. K.; Ryazantsev, D. Y. Rolling Circle Amplification with Fluorescently Labeled DUTP—Balancing the Yield and Degree of Labeling. Anal Bioanal Chem, 2021, 413(14), 3737–3748. doi: 10.1007/s00216-021-03322-7
  321. Zhao, Y.; Liu, R.; Fan, Y.; Zhao, B.; Qian, W.; Guo, J.; Li, C.; Chen, S.; Luo, G.; Deng, H.; Zhang, J. Self-Sealing Hemostatic and Antibacterial Needles by Polyphenol-Assisted Surface Self-Assembly of Multifunctional Nanoparticles. Chemical Engineering Journal, 2021, 425, 130621. doi: 10.1016/j.cej.2021.130621
  322. Zisis, T.; Schwarz, J.; Balles, M.; Kretschmer, M.; Nemethova, M.; Chait, R.; Hauschild, R.; Lange, J.; Guet, C.; Sixt, M.; Zahler, S. Sequential and Switchable Patterning for Studying Cellular Processes under Spatiotemporal ControlACS Appl. Mater. Interfaces 2021, 13 (30), 35545–35560. https://doi.org/. ACS Appl. Mater. Interfaces, 2021, 13(30), 35545–35560. doi: 10.1021/acsami.1c09850
  323. Zisis, T.; Schwarz, J.; Balles, M.; Kretschmer, M.; Nemethova, M.; Chait, R.; Hauschild, R.; Lange, J.; Guet, C.; Sixt, M.; Zahler, S. Sequential and Switchable Patterning for Studying Cellular Processes under Spatiotemporal Control. ACS Appl. Mater. Interfaces, 2021, 13(30), 35545–35560. doi: 10.1021/acsami.1c09850
  324. Sapozhnikova, Y. P.; Koroleva, A. G.; Yakhnenko, V. M.; Khanaev, I. V.; Glyzina, O. Y.; Avezova, T. N.; Volkova, A. A.; Mushinskaya, A. V.; Tyagun, M. L.; Shagun, A. N.; Makarov, M. M.; Kirilchik, S. V.; Sudakov, N. P.; Klimenkov, I. V.; Sukhanova, L. V. Sex Associated Effects of Noise Pollution in Stone Sculpin (Paracottus Knerii) as a Model Object in the Context of Human-Induced Rapid Environmental Change. Biology, 2021, 10(10), 1063. doi: 10.3390/biology10101063
  325. Nishiyama, K.; Maeki, M.; Ishida, A.; Tani, H.; Hisamoto, H.; Tokeshi, M. Simple Approach for Fluorescence Signal Amplification Utilizing a Poly(Vinyl Alcohol)-Based Polymer Structure in a Microchannel. ACS Omega, 2021, 6(12), 8340–8345. doi: 10.1021/acsomega.1c00057
  326. Yang, Z.; Xu, H.; Wang, J.; Chen, W.; Zhao, M. Single-Molecule Fluorescence Techniques for Membrane Protein Dynamics Analysis. Appl Spectrosc, 2021, 75(5), 491–505. doi: 10.1177/00037028211009973
  327. Reddi, R. N.; Rogel, A.; Resnick, E.; Gabizon, R.; Prasad, P. K.; Gurwicz, N.; Barr, H.; Shulman, Z.; London, N. Site-Specific Labeling of Endogenous Proteins Using CoLDR Chemistry. J. Am. Chem. Soc., 2021, 143(48), 20095–20108. doi: 10.1021/jacs.1c06167
  328. Robinson, N. J.; Miyagi, M.; Scarborough, J. A.; Scott, J. G.; Taylor, D. J.; Schiemann, W. P. SLX4IP Promotes RAP1 SUMOylation by PIAS1 to Coordinate Telomere Maintenance through NF-ΚB and Notch Signaling. Science Signaling, 2021, 14(689), eabe9613. doi: 10.1126/scisignal.abe9613
  329. Gonzalez-Valdivieso, J.; Garcia-Sampedro, A.; Hall, A. R.; Girotti, A.; Arias, F. J.; Pereira, S. P.; Acedo, P. Smart Nanoparticles as Advanced Anti-Akt Kinase Delivery Systems for Pancreatic Cancer Therapy. ACS Appl. Mater. Interfaces, 2021, 13(47), 55790–55805. doi: 10.1021/acsami.1c14592
  330. Lobov, A. A.; Babkina, I. Y.; Danilov, L. G.; Masharskiy, A. E.; Predeus, A. V.; Mikhailova, N. A.; Granovitch, A. I.; Maltseva, A. L. Species-Specific Proteins in the Oviducts of Snail Sibling Species: Proteotranscriptomic Study of Littorina Fabalis and L. Obtusata. Biology, 2021, 10(11), 1087. doi: 10.3390/biology10111087
  331. Huynh, G. T.; Henderson, E. C.; Frith, J. E.; Meagher, L.; Corrie, S. R. Stability and Performance Study of Fluorescent Organosilica PH Nanosensors. Langmuir, 2021, 37(21), 6578–6587. doi: 10.1021/acs.langmuir.1c00936
  332. Shalaeva, A. Y.; Kostyuchenko, R. P.; Kozin, V. V. Structural and Functional Characterization of the FGF Signaling Pathway in Regeneration of the Polychaete Worm Alitta Virens (Annelida, Errantia). Genes, 2021, 12(6), 788. doi: 10.3390/genes12060788
  333. Patel, N.; Ji, N.; Wang, Y.; Li, X.; Langley, N.; Tan, C. Subcutaneous Delivery of Albumin: Impact of Thermosensitive Hydrogels. AAPS PharmSciTech, 2021, 22(3), 120. doi: 10.1208/s12249-021-01982-3
  334. Hofmeister, A.; Jahn-Hofmann, K.; Brunner, B.; Helms, M. W.; Metz-Weidmann, C.; Krack, A.; Kurz, M.; Li, Z.; Weitzenberg, M. M.; Pflimlin, E.; Plettenburg, O.; Scheidler, S. Syntheses of Morpholine-Based Nucleotide Analogs for Hepatic SiRNA Targeting and Stabilization. J. Med. Chem., 2021, 64(10), 6838–6855. doi: 10.1021/acs.jmedchem.1c00144
  335. Machulkin, A. E.; Shafikov, R. R.; Uspenskaya, A. A.; Petrov, S. A.; Ber, A. P.; Skvortsov, D. A.; Nimenko, E. A.; Zyk, N. U.; Smirnova, G. B.; Pokrovsky, V. S.; Abakumov, M. A.; Saltykova, I. V.; Akhmirov, R. T.; Garanina, A. S.; Polshakov, V. I.; Saveliev, O. Y.; Ivanenkov, Y. A.; Aladinskaya, A. V.; Finko, A. V.; Yamansarov, E. U.; Krasnovskaya, O. O.; Erofeev, A. S.; Gorelkin, P. V.; Dontsova, O. A.; Beloglazkina, E. K.; Zyk, N. V.; Khazanova, E. S.; Majouga, A. G. Synthesis and Biological Evaluation of PSMA Ligands with Aromatic Residues and Fluorescent Conjugates Based on Them. J. Med. Chem., 2021, 64(8), 4532–4552. doi: 10.1021/acs.jmedchem.0c01935
  336. Tuzikov, A. B.; Rapoport, E. M.; Khaidukov, S. V.; Nokel, E. A.; Knirel, Y. A.; Bovin, N. V. Synthesis of Bodipy-Labeled Bacterial Polysaccharides and Their Interaction with Human Dendritic Cells. Glycoconj J, 2021, 38(3), 369–374. doi: 10.1007/s10719-021-09993-9

2020

  1. Janiszewski, T.; Kołt, S.; Kaiserman, D.; Snipas, S. J.; Li, S.; Kulbacka, J.; Saczko, J.; Bovenschen, N.; Salvesen, G.; Drąg, M.; Bird, P. I.; Kasperkiewicz, P. Noninvasive Optical Detection of Granzyme B from Natural Killer Cells with Enzyme-Activated Fluorogenic Probes. Journal of Biological Chemistry, 2020, 295(28), 9567–9582. doi: 10.1074/jbc.RA120.013204
  2. Toyonaga, T.; Steinbach, E. C.; Keith, B. P.; Barrow, J. B.; Schaner, M. R.; Wolber, E. A.; Beasley, C.; Huling, J.; Wang, Y.; Allbritton, N. L.; Chaumont, N.; Sadiq, T. S.; Koruda, M. J.; Jain, A.; Long, M. D.; Barnes, E. L.; Herfarth, H. H.; Isaacs, K. L.; Hansen, J. J.; Shanahan, M. T.; Rahbar, R.; Furey, T. S.; Sethupathy, P.; Sheikh, S. Z. Decreased Colonic Activin Receptor-Like Kinase 1 Disrupts Epithelial Barrier Integrity in Patients With Crohn’s Disease. Cellular and Molecular Gastroenterology and Hepatology, 2020, 10(4), 779–796. doi: 10.1016/j.jcmgh.2020.06.005
  3. Wang, Y.; Yao, J.; Cai, L.; Liu, T.; Wang, X.; Zhang, Y.; Zhou, Z.; Li, T.; Liu, M.; Lai, R.; Liu, X. Bone-Targeted Extracellular Vesicles from Mesenchymal Stem Cells for Osteoporosis Therapy. IJN, 2020, 15, 7967–7977. doi: 10.2147/IJN.S263756
  4. Wang, Y.; Kathiresan, V.; Chen, Y.; Hu, Y.; Jiang, W.; Bai, G.; Liu, G.; Qin, P. Z.; Fang, X. Posttranscriptional Site-Directed Spin Labeling of Large RNAs with an Unnatural Base Pair System under Non-Denaturing Conditions. Chem. Sci., 2020, 11(35), 9655–9664. doi: 10.1039/D0SC01717E
  5. Mohammad-Beigi, H.; Hayashi, Y.; Zeuthen, C. M.; Eskandari, H.; Scavenius, C.; Juul-Madsen, K.; Vorup-Jensen, T.; Enghild, J. J.; Sutherland, D. S. Mapping and Identification of Soft Corona Proteins at Nanoparticles and Their Impact on Cellular Association. Nature Communications, 2020, 11(1), 4535. doi: 10.1038/s41467-020-18237-7
  6. Bakker, R.; Mani, M.; Carthew, R. W. The Wg and Dpp Morphogens Regulate Gene Expression by Modulating the Frequency of Transcriptional Bursts. eLife, 2020, 9, e56076. doi: 10.7554/eLife.56076
  7. Poreba, M.; Groborz, K. M.; Rut, W.; Pore, M.; Snipas, S. J.; Vizovisek, M.; Turk, B.; Kuhn, P.; Drag, M.; Salvesen, G. S. Multiplexed Probing of Proteolytic Enzymes Using Mass Cytometry-Compatible Activity-Based Probes. J. Am. Chem. Soc, 2020, 142(39), 16704–16715. doi: 10.1021/jacs.0c06762
  8. Ast, J.; Arvaniti, A.; Fine, N. H. F.; Nasteska, D.; Ashford, F. B.; Stamataki, Z.; Koszegi, Z.; Bacon, A.; Jones, B. J.; Lucey, M. A.; Sasaki, S.; Brierley, D. I.; Hastoy, B.; Tomas, A.; D’Agostino, G.; Reimann, F.; Lynn, F. C.; Reissaus, C. A.; Linnemann, A. K.; D’Este, E.; Calebiro, D.; Trapp, S.; Johnsson, K.; Podewin, T.; Broichhagen, J.; Hodson, D. J. Super-Resolution Microscopy Compatible Fluorescent Probes Reveal Endogenous Glucagon-like Peptide-1 Receptor Distribution and Dynamics. Nature Communications, 2020, 11(1), 467. doi: 10.1038/s41467-020-14309-w
  9. Haider, N.; Dutt, P.; van de Kooij, B.; Ho, J.; Palomero, L.; Pujana, M. A.; Yaffe, M.; Stambolic, V. NEK10 Tyrosine Phosphorylates P53 and Controls Its Transcriptional Activity. Oncogene, 2020, 39(30), 5252–5266. doi: 10.1038/s41388-020-1361-x
  10. Park, D.J.; Yun, W.S.; Kim, W.C.; Park, J.-E.; Lee, S.H.; Ha, S.; Choi, J.S.; Key, J.; Seo, Y.J. Improvement of stem cell-derived exosome release efficiency by surface modified nanoparticles. Journal of Nanobiotechnology, 2020, 18(1), 178. doi: 10.1186/s12951-020-00739-7
  11. Bitarishvili, S. V. and Bondarenko, V. S. and Geras'kin, S. A. Expression of Gibberelline Biosynthesis and Catabolism Genes in the Embryos of γ-Irradiated Barley Seeds. Biology Bulletin, 2020, 47(11), 1558–1563. doi: 10.1134/S1062359020110059
  12. Molotkov, A.; Bhatt, N.; Doubrovin, M.; Castrillon, J.; Massa, C.; Gerber, A.; D'Armiento, J.; Goldklang, M.; Mintz, A. Multimodality molecular imaging of the alveolar-capillary barrier in lung disease using albumin based optical and PET tracers. Molecular Biomedicine, 2020, 1(1), 17. doi: 10.1186/s43556-020-00020-1
  13. Gusev, I.D.; Firsov, A.M.; Chertkova, R.V.; Kotova, E.A.; Dolgikh, D.A.; Kirpichnikov, M.P.; Antonenko, Y.N. Study of Interaction of Fluorescent Cytochrome C with Liposomes, Mitochondria, and Mitoplasts by Fluorescence Correlation Spectroscopy. Russian Journal of Bioorganic Chemistry, 2020, 46(6), 1162–1171. doi: 10.1134/S1068162020060084
  14. Liu, Z.; Yuan, J.; Lasorella, A.; Iavarone, A.; Bruce, J.N.; Canoll, P.; Sims, P.A. Integrating single-cell RNA-seq and imaging with SCOPE-seq2. Scientific Reports, 2020, 10, 19482. doi: 10.1038/s41598-020-76599-w
  15. Wang, J.; Li, T.; Wang, J.-L.; Xu, Z.; Meng, W.; Wu, Q.-F. Talpid3-Mediated Centrosome Integrity Restrains Neural Progenitor Delamination to Sustain Neurogenesis by Stabilizing Adherens Junctions. Cell Reports, 2020, 33(11), 108495. doi: 10.1016/j.celrep.2020.108495
  16. Peng, B.; Tong, Z.; Tong, W.Y.; Pasic, P.J.; Oddo, A.; Dai, Y.; Luo, M.; Frescene, J.; Welch, N.G.; Easton, C.D.; Thissen, H.; Voelcker, N.H. In Situ Surface Modification of Microfluidic Blood–Brain-Barriers for Improved Screening of Small Molecules and Nanoparticles. ACS Applied Materials & Interfaces, 2020, 12(51), 56753–56766. doi: 10.1021/acsami.0c17102
  17. Poudel, K.; Banstola, A.; Gautam, M.; Soe, Z.; Phung, C.D.; Pham, L.M.; Jeong, J.-H.; Choi, H.-G.; Ku, S.K.; Tran, T.H.; Yong, C.S.; Kim, J.O. Macrophage-Membrane-Camouflaged Disintegrable and Excretable Nanoconstruct for Deep Tumor Penetration. ACS Applied Materials & Interfaces, 2020, 12(51), 56767–56781. doi: 10.1021/acsami.0c17235
  18. Boersma, S.; Rabouw, H.H.; Bruurs, L.J.M.; Pavlovič, T.; van Vliet, A.L.W.; Beumer, J.; Clevers, H.; van Kuppeveld, F.J.M.; Tanenbaum, M.E. Translation and Replication Dynamics of Single RNA Viruses. Cell, 2020, 183(7), 1930–1945.e23. doi: 10.1016/j.cell.2020.10.019
  19. Brachi, G.; Ruiz-Ramírez, J.; Dogra, P.; Wang, Z.; Cristini, V.; Ciardelli, G.; Rostomily, R.C.; Ferrari, M.; Mikheev, A.M.; Blanco, E.; Mattu, C. Intratumoral injection of hydrogel-embedded nanoparticles enhances retention in glioblastoma. Nanoscale, 2020, 12(46), 23838–23850. doi: 10.1039/d0nr05053a
  20. Yang, S.-J.; Huang, C.-H.; Yang, J.-C.; Wang, C.-H.; Shieh, M.-J. Residence Time-Extended Nanoparticles by Magnetic Field Improve the Eradication Efficiency of Helicobacter pylori. ACS Applied Materials & Interfaces, 2020, 12(49), 54316–54327. doi: 10.1021/acsami.0c13101
  21. Qiu, C.-X.; Bai, X.-F.; Shen, Y.; Zhou, Z.; Pan, L.-Q.; Xu, Y.-C.; Zhao, W.-B.; Chen, S.-Q. Specific Inhibition of Tumor Growth by T Cell Receptor-Drug Conjugates Targeting Intracellular Cancer-Testis Antigen NY-ESO-1/LAGE-1. Bioconjugate Chemistry, 2020, 31(12), 2767–2778. doi: 10.1021/acs.bioconjchem.0c00548
  22. Som, M.; Lal, R.; Ruiz-Velasco, V. Lipid-Encapsulated Silica Nanobowls as an Efficient and Versatile DNA Delivery System. Bioconjugate Chemistry, 2020, 31(12), 2697–2711. doi: 10.1021/acs.bioconjchem.0c00493
  23. Gunasekaran, P.; Yim, M.S.; Ahn, M.; Soung, N.-K.; Park, J.-E.; Kim, J.; Bang, G.; Shin, S.C.; Choi, J.; Kim, M.; Kim, H.N.; Lee, Y.-H.; Chung, Y.-H.; Lee, K.; Kim, E.E.; Jeon, Y.-H.; Kim, M.J.; Lee, K.-R.; Kim, B.-Y.; Lee, K.S.; Ryu, E.K.; Bang, J.K. Development of a Polo-like Kinase-1 Polo-Box Domain Inhibitor as a Tumor Growth Suppressor in Mice Models. Journal of Medicinal Chemistry, 2020, 63(23), 14905–14920. doi: 10.1021/acs.jmedchem.0c01451
  24. Teng, F.-Y.; Wang, T.-T.; Guo, H.-L.; Xin, B.-G.; Sun, B.; Dou, S.-X.; Xi, X.-G.; Hou, X.-M. The HRDC domain oppositely modulates the unwinding activity of E. coli RecQ helicase on duplex DNA and G-quadruplex. The Journal of Biological Chemistry, 2020, 295, 17646–17658. doi: 10.1074/jbc.RA120.015492
  25. Volz, J.; Kusch, C.; Beck, S.; Popp, M.; Vögtle, T.; Meub, M.; Scheller, I.; Heil, H.S.; Preu, J.; Schuhmann, M.K.; Hemmen, K.; Premsler, T.; Sickmann, A.; Heinze, K.G.; Stegner, D.; Stoll, G.; Braun, A.; Sauer, M.; Nieswandt, B. BIN2 orchestrates platelet calcium signaling in thrombosis and thrombo-inflammation. Journal of Clinical Investigation, 2020, 130(11), 6064–6079. doi: 10.1172/JCI136457
  26. Wang, Y.; van Steenbergen, M.J.; Beztsinna, N.; Shi, Y.; Lammers, T.; van Nostrum, C.F.; Hennink, W.E. Biotin-decorated all-HPMA polymeric micelles for paclitaxel delivery. Journal of Controlled Release, 2020, 328, 970–984. doi: 10.1016/j.jconrel.2020.09.013
  27. Huayamares, S.G.; Song, J.Y.; Huang, A.; Crowl, S.R.; Groer, C.E.; Forrest, M.L.; Berkland, C.J. Constructing a Biomaterial to Simulate Extracellular Drug Transport in Solid Tumors. Macromolecular Bioscience, 2020, 20(12), 2000251. doi: 10.1002/mabi.202000251
  28. Deol, K.K.; Crowe, S.O.; Du, J.; Bisbee, H.A.; Guenette, R.G.; Strieter, E.R. Proteasome-Bound UCH37/UCHL5 Debranches Ubiquitin Chains to Promote Degradation. Molecular Cell, 2020, 80(5), 796–809.e9. doi: 10.1016/j.molcel.2020.10.017
  29. Chen, D.; Wang, Z.; Zhao, Y.G.; Zheng, H.; Zhao, H.; Liu, N.; Zhang, H. Inositol Polyphosphate Multikinase Inhibits Liquid-Liquid Phase Separation of TFEB to Negatively Regulate Autophagy Activity. Developmental Cell, 2020, 55(5), 588–602.e7. doi: 10.1016/j.devcel.2020.10.010
  30. Altenburg, W.J.; Yewdall, N.A.; Vervoort, D.F.M.; van Stevendaal, M.H.M.E.; Mason, A.F.; van Hest, J.C.M. Programmed spatial organization of biomacromolecules into discrete, coacervate-based protocells. Nature Communications, 2020, 11, 6282. doi: 10.1038/s41467-020-20124-0
  31. Wang, Z.; Cui, M.; Shah, A.M.; Tan, W.; Liu, N.; Bassel-Duby, R.; Olson, E.N. Cell-Type-Specific Gene Regulatory Networks Underlying Murine Neonatal Heart Regeneration at Single-Cell Resolution. Cell Reports, 2020, 33(10), 108472. doi: 10.1016/j.celrep.2020.108472
  32. Clavé, G.; Vasseur, J.-J.; Smietana, M. The Sulfo-Click Reaction and Dual Labeling of Nucleosides. Current Protocols in Nucleic Acid Chemistry, 2020, 83(1), e120. doi: 10.1002/cpnc.120
  33. Huang, D.; Yue, F.; Qiu, J.; Deng, M.; Kuang, S. Polymeric nanoparticles functionalized with muscle-homing peptides for targeted delivery of phosphatase and tensin homolog inhibitor to skeletal muscle. Acta Biomaterialia, 2020, 118, 196–206. doi: 10.1016/j.actbio.2020.10.009
  34. Melentiev, P.N.; Son, L.V.; Kudryavtsev, D.S.; Kasheverov, I.E.; Tsetlin, V.I.; Esenaliev, R.O.; Balykin, V.I. Ultrafast, Ultrasensitive Detection and Imaging of Single Cardiac Troponin-T Molecules. ACS Sensors, 2020, 5(11), 3576–3583. doi: 10.1021/acssensors.0c01790
  35. Landry, M.R.; DuRoss, A.N.; Neufeld, M.J.; Hahn, L.; Sahay, G.; Luxenhofer, R.; Sun, C. Low Dose Novel PARP-PI3K Inhibition via Nanoformulation Improves Colorectal Cancer Immuno-Radiotherapy. Materials Today Bio, 2020, 8, 100082. doi: 10.1016/j.mtbio.2020.100082
  36. Gerosa, L.; Chidley, C.; Fröhlich, F.; Sanchez, G.; Lim, S.K.; Muhlich, J.; Chen, J.-Y.; Vallabhaneni, S.; Baker, G.J.; Schapiro, D.; Atanasova, M.I.; Chylek, L.A.; Shi, T.; Yi, L.; Nicora, C.D.; Claas, A.; Ng, T.S.C.; Kohler, R.H.; Lauffenburger, D.A.; Weissleder, R.; Miller, M.A.; Qian, W.-J.; Wiley, H.S.; Sorger, P.K. Receptor-Driven ERK Pulses Reconfigure MAPK Signaling and Enable Persistence of Drug-Adapted BRAF-Mutant Melanoma Cells. Cell Systems, 2020, 11(5), 478–494.e9. doi: 10.1016/j.cels.2020.10.002
  37. Jiang, Z.; He, H.; Liu, H.; Thayumanavan, S. Azide-Terminated RAFT Polymers for Biological Applications. Current Protocols in Chemical Biology, 2020, 12(4), e85. doi: 10.1002/cpch.85
  38. Dettling, S.E.; Ahmadi, M.; Lin, Z.; He, L.; Matthews, M.L. Discovery of Electrophiles and Profiling of Enzyme Cofactors. Current Protocols in Chemical Biology, 2020, 12(4), e86. doi: 10.1002/cpch.86
  39. Kim, S.M.; Park, J.; Kim, M.S.; Song, H.; Jo, A.; Park, H.; Kim, T.S.; Choi, S.H.; Park, S.B. Phenotypic Discovery of an Antivirulence Agent against Vibrio vulnificus via Modulation of Quorum-Sensing Regulator SmcR. ACS Infectious Diseases, 2020, 6(11), 3076–3082. doi: 10.1021/acsinfecdis.0c00587
  40. Vallmitjana, A.; Torrado, B.; Dvornikov, A.; Ranjit, S.; Gratton, E. Blind Resolution of Lifetime Components in Individual Pixels of Fluorescence Lifetime Images Using the Phasor Approach. Journal of Physical Chemistry B, 2020, 124(45), 10126–10137. doi: 10.1021/acs.jpcb.0c06946
  41. Covarrubias-Zambrano, O.; Shrestha, T.B.; Pyle, M.; Montes-Gonzalez, M.L.; Troyer, D.L.; Bossmann, S.H. Development of a gene delivery system composed of a cell penetrating peptide and a nontoxic polymer. ACS Applied Bio Materials, 2020, 3(11), 7418–7427. doi: 10.1021/acsabm.0c00561
  42. Hargrove, D.; Liang, B.; Kashfi-Sadabadi, R:; Joshi, G.N:; Gonzalez-Fajardo, L.; Glass, S.; Jay, M.; Salner, A.; Lu, X. Tumor-mesoporous silica nanoparticle interactions following intraperitoneal delivery for targeting peritoneal metastasis. Journal of Controlled Release, 2020, 328, 846–858. doi: 10.1016/j.jconrel.2020.11.003
  43. Li, W.; Suarato, G.; Cathcart, J.M.; Sargunas, P.R.; Meng, Y. Design, characterization, and intracellular trafficking of biofunctionalized chitosan nanomicelles. Biointerphases, 2020, 15, 061003. doi: 10.1116/6.0000380
  44. Catipovic, M.A.; Rapoport, T.A. Protease protection assays show polypeptide movement into the SecY channel by power strokes of the SecA ATPase. EMBO Reports, 2020, 21(11), e50905. doi: 10.15252/embr.202050905
  45. Binkley, M.; Cui, M.; Berezin, M.; Meacham, J.M. Antibody conjugate assembly on ultrasound-confined microcarrier particles. ACS Biomaterials Science & Engineering, 2020, 6(11), 6108–6116. doi: 10.1021/acsbiomaterials.0c01162
  46. Bobrin, V.A.; Lin, Y.; He, J.; Qi, Y.; Gu, W.; Monteiro, M.J. Therapeutic Delivery of Polymeric Tadpole Nanostructures with High Selectivity to Triple Negative Breast Cancer Cells. Biomacromolecules, 2020, 21(11), 4457–4468. doi: 10.1021/acs.biomac.0c00302
  47. Hong, K.; Song, D.; Jung, Y. Behavior control of membrane-less protein liquid condensates with metal ion-induced phase separation. Nature Communications, 2020, 11, 5554. doi: 10.1038/s41467-020-19391-8
  48. Jose, G.; Lu, Y.-J.; Hung, J.-T.; Yu, A.L.; Chen, J.-P. Co-Delivery of CPT-11 and Panobinostat with Anti-GD2 Antibody Conjugated Immunoliposomes for Targeted Combination Chemotherapy. Cancers, 2020, 12(11), 3211. doi: 10.3390/cancers12113211
  49. Iurova, E.; Beloblov, I.; Beloborodov, E.; Rastorgueva, E.; Pogodina, E.; Tazintseva, E.; Saenko, Y.; Fomin, A. Use of Natural Peptides with a Cysteine Knot of Arthropods as a Carrier of a Peptide Tropic to Glutamate Carboxypeptidase II. Systematic Reviews in Pharmacy, 2020, 11(9), 503–509. doi: 10.31838/srp.2020.9.73
  50. Ruano-Salguero, J.S.; Lee, K.H. Adsorptive-mediated endocytosis of Sulfo-Cy5-labeled IgG causes aberrant IgG processing by brain endothelial-like cells. Molecular Pharmaceutics, 2020, 17(11), 4280–4285. doi: 10.1021/acs.molpharmaceut.0c00712
  51. Shipunova, V.O.; Komedchikova, E.N.; Kotelnikova, P.A.; Zelepukin, I.V.; Schulga, A.A.; Proshkina, G.M.; Shramova, E.I.; Kutscher, H.L.; Telegin, G.B.; Kabashin, A.V.; Prasad, P.N.; Deyev, S.M. Dual Regioselective Targeting the Same Receptor in Nanoparticle-Mediated Combination Immuno/Chemotherapy for Enhanced Image-Guided Cancer Treatment. ACS Nano, 2020, 14(10), 12781–12795. doi: 10.1021/acsnano.0c03421
  52. Ghimire, C.; Wang, H.; Li, H.; Vieweger, M.; Xu, C.; Guo, P. RNA Nanoparticles as Rubber for Compelling Vessel Extravasation to Enhance Tumor Targeting and for Fast Renal Excretion to Reduce Toxicity. ACS Nano, 2020, 14(10), 13180–13191. doi: 10.1021/acsnano.0c04863
  53. Sokolova, V.; Mekky, G.; van der Meer, S.B.; Seeds, M.C.; Atala, A.J.; Epple, M. Transport of ultrasmall gold nanoparticles (2 nm) across the blood-brain barrier in a six-cell brain spheroid model. Scientific Reports, 2020, 10, 18033. doi: 10.1038/s41598-020-75125-2
  54. Álamo, P.; Pallarès, V.; Céspedes, M.; Falgàs, A.; Sanchez, J.M.; Serna, N.; Sánchez-García, L.; Voltà-Duràn, E.; Morris, G.A.; Sánchez-Chardi, A.; Casanova, I.; Mangues, R.; Vazquez, E.; Villaverde, A.; Unzueta, U. Fluorescent Dye Labeling Changes the Biodistribution of Tumor-Targeted Nanoparticles. Pharmaceutics, 2020, 12(11), 1004. doi: 10.3390/pharmaceutics12111004
  55. Vervoort, D.F.M.; Pretto, C.; van Hest, J.C.M. Insight into N-terminal localization and dynamics of engineered virus-like particles. RSC Advances, 2020, 10(64), 38774–38781. doi: 10.1039/D0RA07612K
  56. Wilder, L.M. Handali, P.R.; Webb, L.J.; Crooks, R.M. Interactions between Oligoethylene Glycol-Capped AuNPs and Attached Peptides Control Peptide Structure. Bioconjugate Chemistry, 2020, 31(10), 2383–2391. doi: 10.1021/acs.bioconjchem.0c00447
  57. Shramova, E.; Proshkina, G.; Shipunova, V.; Ryabova, A.; Kamyshinsky, R.; Konevega, A.; Schulga, A.; Konovalova, E.; Telegin, G.; Deyev, S. Dual Targeting of Cancer Cells with DARPin-Based Toxins for Overcoming Tumor Escape. Cancers, 2020, 12(10), 3014. doi: 10.3390/cancers12103014
  58. Saito, E.; Gurczynski, S.J.; Kramer, K.R.; Wilke, C.A.; Miller, S.D.; Moore, B.B.; Shea, L.D. Modulating lung immune cells by pulmonary delivery of antigen-specific nanoparticles to treat autoimmune disease. Science Advances, 2020, 6(42), eabc9317. doi: 10.1126/sciadv.abc9317
  59. McCrorie, P.; Mistry, J.; Taresco, V.; Lovato, T.; Fay, M.; Ward, I.; Ritchie, A.A.; Clarke, P.A.; Smith, S.J.; Marlow, M.; Rahman, R. Etoposide and olaparib polymer-coated nanoparticles within a bioadhesive sprayable hydrogel for post-surgical localised delivery to brain tumours. European Journal of Pharmaceutics and Biopharmaceutics, 2020, 157, 108–120. doi: 10.1016/j.ejpb.2020.10.005
  60. Choi, Y.; Han, H.; Jeon, S.; Yoon, H.Y.; Kim, H.; Kwon, I.C.; Kim, K. Deep Tumor Penetration of Doxorubicin-Loaded Glycol Chitosan Nanoparticles Using High-Intensity Focused Ultrasound. Pharmaceutics, 2020, 12(10), 974. doi: 10.3390/pharmaceutics12100974
  61. Zahnreich, S.; Weber, B.; Rösch, G.; Schindler, D.; Schmidberger, H. Compromised repair of radiation-induced DNA double-strand breaks in Fanconi anemia fibroblasts in G2. DNA Repair, 2020, 96, 102992. doi: 10.1016/j.dnarep.2020.102992
  62. Zhang, M.; Zhou, L.; Xu, Y.; Yang, M.; Xu, Y.; Komaniecki, G.P.; Kosciuk, T.; Chen, X.; Lu, X.; Zou, X.; Linder, M.E.; Lin, H. A STAT3 palmitoylation cycle promotes TH17 differentiation and colitis. Nature, 2020, 586(7829), 434–439. doi: 10.1038/s41586-020-2799-2
  63. Chen, J.; Guo, Y.; Li, H.; Zhang, C.; Chang, X.; Ma, R.; Cheng, H.; Ye, X.; Cui, H.; Li, Y. Near-infrared dye-labeled antibody COC183B2 enables detection of tiny metastatic ovarian cancer and optimizes fluorescence-guided surgery. Journal of Surgical Oncology, 2020, 122(6), 1207–1217. doi: 10.1002/jso.26130
  64. Agote-Aran, A.; Schmucker, S.; Jerabkova, K.; Jmel Boyer, I.; Berto, A.; Pacini, L.; Ronchi, P.; Kleiss, C.; Guerard, L.; Schwab, Y.; Moine, H.; Mandel, J.-L.; Jacquemont, S.; Bagni, C.; Sumara, I. Spatial control of nucleoporin condensation by fragile X-related proteins. EMBO Journal, 2020, 39(20), e104467. doi: 10.15252/embj.2020104467
  65. Hortelão, Ana C. and García-Jimeno, S.; Cano-Sarabia, M.; Patiño, T.; Maspoch, D.; Sanchez, S. LipoBots: Using Liposomal Vesicles as Protective Shell of Urease-Based Nanomotors. Advanced Functional Materials, 2020, 30(42), 2002767. doi: 10.1002/adfm.202002767
  66. Zhang, W.; Teske, N.; Samadi, M.; Sarem, M.; Shastri, V.P. Unraveling the role of β1 integrin isoforms in cRGD-mediated uptake of nanoparticles bearing hydrophilized alkyne moieties in epithelial and endothelial cells. Acta Biomaterialia, 2020, 116, 344–355. doi: 10.1016/j.actbio.2020.08.038
  67. Hifni, B.; Khan, M.; Devereux, S.J.; Byrne, M.H.; Quinn, S.J.; Simpson, J.C. Investigation of the cellular destination of fluorescently labelled carbon nanohorns in cultured cells. ACS Applied Bio Materials, 2020, 3(10), 6790–6801. doi: 10.1021/acsabm.0c00748
  68. Park, H.; Gladstone, M.; Shanley, C.; Goodrich, R.; Guth, A. A novel cancer immunotherapy utilizing autologous tumour tissue. Vox Sanguinis, 2020, 115(6), 525–535. doi: 10.1111/vox.12935
  69. Kovacs, L.; Cabral, P.; Chammas, R. Mannose receptor 1 expression does not determine the uptake of high-density mannose dendrimers by activated macrophages populations. PloS One, 2020, 15(10), e0240455. doi: 10.1371/journal.pone.0240455
  70. Kang, J.; Lhee, S.; Lee, J.K.; Zare, R.N.; Nam, H.G. Restricted intramolecular rotation of fluorescent molecular rotors at the periphery of aqueous microdroplets in oil. Scientific Reports, 2020, 10, 16859. doi: 10.1038/s41598-020-73980-7
  71. van der Linden, C.J.; Gupta, P.; Bhuiya, A.I.; Riddick, K.R.; Hossain, K.; Santoro, S.W. Olfactory Stimulation Regulates the Birth of Neurons That Express Specific Odorant Receptors. Cell Reports, 2020, 33(1), 108210. doi: 10.1016/j.celrep.2020.108210
  72. Lee, J.; Kim, J.-H.; You, D.G.; Kim, S.; Um, W.; Jeon, J.; Kim, C.H.; Joo, H.; Yi, G.-R.; Park, J.H. Cavitation-Inducible Mesoporous Silica-Titania Nanoparticles for Cancer Sonotheranostics. Advanced Healthcare Materials, 2020, 9(19), 2000877. doi: 10.1002/adhm.202000877
  73. Islam, M.R.; Nguy, C.; Pandit, S.; Lyon, L.A. Design and Synthesis of Core–Shell Microgels with One‐Step Clickable Crosslinked Cores and Ultralow Crosslinked Shells. Macromolecular Chemistry and Physics, 2020, 221(19), 2000156. doi: 10.1002/macp.202000156
  74. Yang, S.W.; Huang, X.; Lin, W.; Min, J.; Miller, D.J.; Mayasundari, A.; Rodrigues, P.; Griffith, E.C.; Gee, C.T.; Li, L.; Li, W.; Lee, R.E.; Rankovic, Z.; Chen, T.; Potts, P.R. Structural basis for substrate recognition and chemical inhibition of oncogenic MAGE ubiquitin ligases. Nature Communications, 2020, 11, 4931. doi: 10.1038/s41467-020-18708-x
  75. Zeng, Y.; Wang, J.; Wang, Z.; Chen, G.; Yu, J.; Li, S.; Li, Q.; Li, H.; Wen, D.; Gu, Z.; Gu, Z. Colloidal crystal microneedle patch for glucose monitoring. Nano Today, 2020, 35, 100984. doi: 10.1016/j.nantod.2020.100984
  76. Li, H.-Y.; Lin, H.-C.; Huang, B.-J.; Lo, A.Z.K.; Saidin, S.; Lai, C.-H. Size Preferences Uptake of Glyco-Silica Nanoparticles to MDA-MB-231 Cell. Langmuir, 2020, 36(38), 11374–11382. doi: 10.1021/acs.langmuir.0c02297
  77. Shuvalova, M.L.; Kopylov, A.T.; Mazurov, D.V.; Pichugin, A.V.; Bovin, N.V.; Filatov, A.V. CD44-Associated Tn Antigen as a New Biomarkerof Tumor Cells with Aberrant Glycosylation. Biochemistry (Moscow), 2020, 85(9), 1064–1071. doi: 10.1134/S0006297920090060
  78. Long, M.; Lu, A.; Lu, M.; Weng, L.; Chen, Q.; Zhu, L.; Chen, Z. Azo-inserted responsive hybrid liposomes for hypoxia-specific drug delivery. Acta Biomaterialia, 2020, 115, 343–357. doi: 10.1016/j.actbio.2020.07.061
  79. Phung, C.D.; Pham, T.T.; Nguyen, H.T.; Nguyen, T.T.; Ou, W.; Jeong, J.-H.; Choi, H.-G.; Ku, S.K.; Yong, C.S.; Kim, J.O. Anti-CTLA-4 Antibody-Functionalized Dendritic Cell-derived Exosomes Targeting Tumor-draining Lymph Nodes for Effective Induction of Antitumor T-cell Responses. Acta Biomaterialia, 2020, 115, 371–382. doi: 10.1016/j.actbio.2020.08.008
  80. Liu, H.-J.; Wang, M.; Hu, X.; Shi, S.; Xu, P. Enhanced Photothermal Therapy through the In Situ Activation of a Temperature and Redox Dual-Sensitive Nanoreservoir of Triptolide. Small, 2020, 16(38), e2003398. doi: 10.1002/smll.202003398
  81. Huang, Y.; Jiang, K.; Zhang, X.; Chung, E.J. The Effect of Size, Charge, and Peptide Ligand Length on Kidney Targeting by Small, Organic Nanoparticles. Bioengineering & Translational Medicine, 2020, 5(3), e10173. doi: 10.1002/btm2.10173
  82. Liu, M.; Apriceno, A.; Sipin, M.; Scarpa, E.; Rodriguez-Arco, L.; Poma, A.; Marchello, G.; Battaglia, G.; Angioletti-Uberti, S. Combinatorial entropy behaviour leads to range selective binding in ligand-receptor interactions. Nature Communications, 2020, 11, 4836. doi: 10.1038/s41467-020-18603-5
  83. Pfister, J.; Lichius, A.; Summer, D.; Haas, H.; Kanagasundaram, T.; Kopka, K.; Decristoforo, C. Live-cell imaging with Aspergillus fumigatus-specific fluorescent siderophore conjugates. Scientific Reports, 2020, 10, 15519. doi: 10.1038/s41598-020-72452-2
  84. Reshitko, G.S.; Yamansarov, E.Y.; Evteev, S.A.; Lopatukhina, E.V.; Shkil', D.O.; Saltykova, I.V.; Lopukhov, A.V.; Kovalev, S.V.; Lobov, A.N.; Kislyakov, I.V.; Burenina, O.Y.; Klyachko, N.L.; Garanina, A.S.; Dontsova, O.A.; Ivanenkov, Y.A.; Erofeev, A.S.; Gorelkin, P.V.; Beloglazkina, E.K.; Majouga, A.G. Synthesis and Evaluation of New Trivalent Ligands for Hepatocyte Targeting via the Asialoglycoprotein Receptor. Bioconjugate Chemistry, 2020, 31(5), 1313–1319. doi: 10.1021/acs.bioconjchem.0c00202
  85. Oh, S.; Boo, K.; Kim, J.; Baek, S.A.; Jeon, Y.; You, J.; Lee, H.; Choi, H.-J.; Park, D.; Lee, J.M.; Baek, S.H. The chromatin-binding protein PHF6 functions as an E3 ubiquitin ligase of H2BK120 via H2BK12Ac recognition for activation of trophectodermal genes. Nucleic Acids Research, 2020, 48(16), 9037–9052. doi: 10.1093/nar/gkaa626
  86. Teng, Y.; Liang, H.; Zhang, Z.; He, Y.; Pan, Y.; Yuan, S.; Wu, X.; Zhao, Q.; Yang, H.; Zhou, P. Biodistribution and immunomodulatory activities of a proteoglycan isolated from Ganoderma lucidum. Journal of Functional Foods, 2020, 74, 104193. doi: 10.1016/j.jff.2020.104193
  87. Susnik, E.; Taladriz-Blanco, P.; Drasler, B.; Balog, S.; Petri-Fink, A.; Rothen-Rutishauser, B. Increased Uptake of Silica Nanoparticles in Inflamed Macrophages but Not upon Co-Exposure to Micron-Sized Particles. Cells, 2020, 9(9), 2099. doi: 10.3390/cells9092099
  88. Hossian, A.K.M.N.; Jois, S.D.; Jonnalagadda, S.C.; Mattheolabakis, G. Nucleic Acid Delivery with α-Tocopherol-Polyethyleneimine-Polyethylene Glycol Nanocarrier System. International Journal of Nanomedicine, 2020, 15, 6689–6703. doi: 10.2147/IJN.S259724
  89. Tugel, U.; Casas, M.G.; Wiltschi, B. Site-Specific Incorporation of Non-canonical Amino Acids by Amber Stop Codon Suppression in Escherichia coli. Peptide and Protein Engineering (Springer Protocols Handbooks), 2020, 267–281. doi: 10.1007/978-1-0716-0720-6_14
  90. Peplau, E.; De Rose, F.; Reder, S.; Mittelhaeuser, M.; Scafetta, G.; Schwaiger, M.; Weber, W.A.; Bartolazzi, A.; Skerra, A.; D'Alessandria, C. Development of a chimeric Fab directed against human galectin-3 and validation as an immune-PET tracer for the sensitive in vivo imaging of thyroid cancer. Thyroid, 2020, 30(9), 1314–1326. doi: 10.1089/thy.2019.0670
  91. Yuan, M.; Chen, X.; Sun, Y.; Jiang, L.; Xia, Z:; Ye, K.; Jiang, H.; Yang, B.; Ying, M.; Cao, J.; He, Q. ZDHHC12-mediated claudin-3 S-palmitoylation determines ovarian cancer progression. Acta Pharmaceutica Sinica B, 2020, 10(8), 1426–1439. doi: 10.1016/j.apsb.2020.03.008
  92. Honda, Y.; Nomoto, T.; Matsui, M.; Takemoto, H.; Kaihara, Y.; Miura, Y.; Nishiyama, N. Sequential Self-Assembly Using Tannic Acid and Phenylboronic Acid-Modified Copolymers for Potential Protein Delivery. Biomacromolecules, 2020, 21(9), 3826–3835. doi: 10.1021/acs.biomac.0c00903
  93. Desai, B.J.; Gonzalez, R.L. Multiplexed genomic encoding of non-canonical amino acids for labeling large complexes. Nature Chemical Biology, 2020, 16, 1129–1135. doi: 10.1038/s41589-020-0599-5
  94. Kim, D.; Lee, S.S.; Yoo, W.Y.; Moon, H.; Cho, A.; Park, S.Y.; Kim, Y.-S.; Kim, H.R.; Lee, H.J. Combination Therapy with Doxorubicin-Loaded Reduced Albumin Nanoparticles and Focused Ultrasound in Mouse Breast Cancer Xenografts. Pharmaceuticals, 2020, 13(9), 235. doi: 10.3390/ph13090235
  95. FitzGerald, L.I.; Aurelio, L.; Chen, M.; Yuen, D.; Rennick, J.J.; Graham, B.; Johnston, A.P.R. A molecular sensor to quantify the localization of proteins, DNA and nanoparticles in cells. Nature Communications, 2020, 11(1), 4482. doi: 10.1038/s41467-020-18082-8
  96. Tischer, D.; Weiner, O. Optogenetic Tuning of Protein-protein Binding in Bilayers Using LOVTRAP. Bio-protocol, 2020, 10(17), e3745. doi: 10.21769/BioProtoc.3745
  97. Xie, H.; Zhu, H.; Zhou, K.; Wan, J.; Zhang, L.; Yang, Z.; Zhou, L.; Chen, X.; Xu, X.; Zheng, S.; Wang, H. Target-oriented delivery of self-assembled immunosuppressant cocktails prolongs allogeneic orthotopic liver transplant survival. Journal of Controlled Release, 2020, 328, 237–250. doi: 10.1016/j.jconrel.2020.08.043
  98. Carreras-Badosa, G.; Maslovskaja, J.; Periyasamy, K.; Urgard, E.; Padari, K.; Vaher, H.; Tserel, L.; Gestin, M.; Kisand, K.; Arukuusk, P.; Lou, C.; Langel, Ü.; Wengel, J.; Pooga, M.; Rebane, A. NickFect type of cell-penetrating peptides present enhanced efficiency for microRNA-146a delivery into dendritic cells and during skin inflammation. Biomaterials, 2020, 262, 120316. doi: 10.1016/j.biomaterials.2020.120316
  99. Benslimane, Y.; Bertomeu, T.; Coulombe-Huntington, J.; McQuaid, M.; Sánchez-Osuna, M.; Papadopoli, D.; Avizonis, D.; De Sa Tavares Russo, M.; Huard, C.; Topisirovic, I.; Wurtele, H.; Tyers, M.; Harrington, L. Genome-Wide Screens Reveal that Resveratrol Induces Replicative Stress in Human Cells. Molecular Cell, 2020, 79(5), 846–856. doi: 10.1016/j.molcel.2020.07.010
  100. Teng, F.; Wu, X.; Libera, M.R. Chemical Orthogonality in Surface-Patterned Poly(ethylene glycol) Microgels. Langmuir, 2020, 36(35), 10622–10627. doi: 10.1021/acs.langmuir.0c02172
  101. Furubayashi, T.; Ishida, K.; Nakata, E.; Morii, T.; Naruse, K.; Matsushita, M.; Fujiyoshi, S. Cryogenic Far-Field Fluorescence Nanoscopy: Evaluation with DNA Origami. Journal of Physical Chemistry B, 2020, 124(35), 7525–7536. doi: 10.1021/acs.jpcb.0c04721
  102. Cassidy, J.; Ellison, C.; Bettinger, J.; Yang, M.; Moroz, P.; Zamkov, M. Enabling Narrow Emission Linewidths in Colloidal Nanocrystals through Coalescence Growth. Chemistry of Materials, 2020, 32(17), 7524–7534. doi: 10.1021/acs.chemmater.0c02874
  103. Wang, C.; Guan, W.; Chen, R.; Levi-Kalisman, Y.; Xu, Y.; Zhang, L.; Zhou, M.; Xu, G.; Dou, H. Fluorescent glycan nanoparticle-based FACS assays for the identification of genuine drug-resistant cancer cells with differentiation potential. Nano Research, 2020, 13(11), 3110–3122. doi: 10.1007/s12274-020-2981-8
  104. Perkins, L.A.; Nyiranshuti, L.; Little-Ihrig, L.; Latoche, J.D.; Day, K.E.; Zhu, Q.; Tavakoli, S.; Sundd, P.; Novelli, E.M.; Anderson, C.J. Integrin VLA-4 as a PET imaging biomarker of hyper-adhesion in transgenic sickle mice. Blood Advances, 2020, 4(17), 4102–4112. doi: 10.1182/bloodadvances.2020002642
  105. Sim, T.; Lim, C.; Hoang, N.H.; Shin, Y.; Kim, J.C.; Park, J.Y.; Her, J.; Lee, E.S.; Youn, Y.S.; Oh, K.T. An On-Demand pH-Sensitive Nanocluster for Cancer Treatment by Combining Photothermal Therapy and Chemotherapy. Pharmaceutics, 2020, 12, 839. doi: 10.3390/pharmaceutics12090839
  106. Tamošiūnė, I.; Gelvonauskienė, D.; Haimi, P.; Mildažienė, V.; Koga, K.; Shiratani, M.; Baniulis, D. Cold Plasma Treatment of Sunflower Seeds Modulates Plant-Associated Microbiome and Stimulates Root and Lateral Organ Growth. Frontiers in Plant Science, 2020, 11, 568924. doi: 10.3389/fpls.2020.568924
  107. Valadares, R.B.S.; Perotto, S.; Lucheta, A.R.; Santos, E.C.; Oliveira, R.M.; Lambais, M.R. Proteomic and Transcriptomic Analyses Indicate Metabolic Changes and Reduced Defense Responses in Mycorrhizal Roots of Oeceoclades maculata (Orchidaceae) Collected in Nature. Journal of Fungi, 2020, 6(3), 148. doi: 10.3390/jof6030148
  108. Sapozhnikova, Y.P.; Koroleva, A.G.; Yakhnenko, V.M.; Tyagun, M.L.; Glyzina, O.Y.; Coffin, A.B.; Makarov, M.M.; Shagun, A.N.; Kulikov, V.A.; Gasarov, P.V.; Kirilchik, S.V.; Klimenkov, I.V.; Sudakov, N.P.; Anoshko, P.N.; Kurashova, N.A.; Sukhanova, L.V. Molecular and cellular responses to long-term sound exposure in peled (Coregonus peled). Journal of the Acoustical Society of America, 2020, 148(2), 895–907. doi: 10.1121/10.0001674
  109. Babity, S.; Polomska, A.K.; Couture, F.; Bonmarin, M.; Fehr, D.; Detmar, M.; Brambilla, D. Rational design of a fluorescent microneedle tattoo for minimally invasive monitoring of lymphatic function. Journal of Controlled Release, 2020, 327, 350–359. doi: 10.1016/j.jconrel.2020.08.017
  110. Thompson, T.A.; Touré, M.B.; Sanogo, D.; Shaffer, J.G.; Doumbia, S.O.; Krogstad, D.J. Template copy number and the sensitivity of quantitative PCR for Plasmodium falciparum in asymptomatic individuals. Malaria Journal, 2020, 19, 295. doi: 10.1186/s12936-020-03365-8
  111. Park, B.G.; Kim, Y.J.; Min, J.H.; Cheong, T.-C.; Nam, S.H.; Cho, N.-H.; Kim, Y.K.; Lee, K.B. Assessment of Cellular Uptake Efficiency According to Multiple Inhibitors of Fe3O4-Au Core-Shell Nanoparticles: Possibility to Control Specific Endocytosis in Colorectal Cancer Cells. Nanoscale Research Letters, 2020, 15, 165. doi: 10.1186/s11671-020-03395-w
  112. Vu, M.N.; Kelly, H.G.; Wheatley, A.K.; Peng, S.; Pilkington, E.H.; Veldhuis, N.A.; Davis, T.P.; Kent, S.J.; Truong, N.P. Cellular Interactions of Liposomes and PISA Nanoparticles during Human Blood Flow in a Microvascular Network. Small, 2020, 16(33), e2002861. doi: 10.1002/smll.202002861
  113. Un Kim, J.; Muhammad Shahbaz, H.; Lee, H.; Kim, T.; Yang, K.; Hoon Roh, Y.; Park, J. Optimization of Phytic acid-crosslinked Chitosan Microspheres for Oral Insulin Delivery Using Responsive Surface Methodology. International Journal of Pharmaceutics, 2020, 588, 119736. doi: 10.1016/j.ijpharm.2020.119736
  114. Locke, L.; Shankaran, K.; Gong, L.; Stoodley, P.; Vozar, S.L.; Cole, S.L.; Tweedle, M.F.; Wozniak, D.J. Evaluation of peptide-based probes towards in vivo diagnostic imaging of bacterial biofilm-associated infections. ACS Infectious Diseases, 2020, 6(8), 2086–2098. doi: 10.1021/acsinfecdis.0c00125
  115. Garafutdinov, R.R.; Gilvanov, A.R.; Kupova, O.Y.; Sakhabutdinova, A.R. Effect of metal ions on isothermal amplification with Bst exo- DNA polymerase. International Journal of Biological Macromolecules, 2020, 161, 1447–1455. doi: 10.1016/j.ijbiomac.2020.08.028
  116. Zaw Thin, M.; Allan, H.; Bofinger, R.; Kostelec, T.D.; Guillaume, S.; Connell, J.J.; Patrick, P.S.; Hailes, H.C.; Tabor, A.B.; Lythgoe, M.F.; Stuckey, D.J.; Kalber, T.L. Multi-modal imaging probe for assessing the efficiency of stem cell delivery to orthotopic breast tumours. Nanoscale, 2020, 12(31), 16570–16585. doi: 10.1039/d0nr03237a
  117. Ramey-Ward, A.N.; Su, H.; Salaita, K. Mechanical stimulation of adhesion receptors using light-responsive nanoparticle actuators enhances myogenesis. ACS Applied Materials & Interfaces, 2020, 12(32), 35903–35917. doi: 10.1021/acsami.0c08871
  118. Mahmoud, A.M.; Morrow, J.P.; Pizzi, D.; Azizah, A.M.; Davis, T.P.; Tabor, R.F.; Kempe, K. Tuning Cellular Interactions of Carboxylic Acid Side Chain Containing Polyacrylates: The Role of Cyanine Dye Label and Side Chain Type. Biomacromolecules, 2020, 21(8), 3007–3016. doi: 10.1021/acs.biomac.0c00244
  119. Yen, H.-C.; Kuo, T.-R.; Huang, M.-H.; Huang, H.-K.; Chen, C.-C. Design of Fluorescence-Enhanced Silver Nanoisland Chips for High-Throughput and Rapid Arsenite Assay. ACS Omega, 2020, 5(31), 19771–19777. doi: 10.1021/acsomega.0c02533
  120. Grätz, L.; Tropmann, K.; Bresinsky, M.; Müller, C.; Bernhardt, G.; Pockes, S. NanoBRET binding assay for histamine H2 receptor ligands using live recombinant HEK293T cells. Scientific Reports, 2020, 10, 13288. doi: 10.1038/s41598-020-70332-3
  121. Paul, M.; Tscheuschner, G.; Herrmann, S.; Weller, M.G. Fast Detection of 2,4,6-Trinitrotoluene (TNT) at ppt Level by a Laser-Induced Immunofluorometric Biosensor. Biosensors, 2020, 10(8), 89. doi: 10.3390/bios10080089
  122. Lix, K.; Krause, K.D.; Kim, H.; Algar, W.R. Investigation of the Energy Transfer Mechanism Between Semiconducting Polymer Dots and Organic Dyes. Journal of Physical Chemistry C, 2020, 124(31), 17387–17400. doi: 10.1021/acs.jpcc.0c04983
  123. Than, A.; Duong, P.K.; Zan, P.; Liu, J.; Leow, M.K.-S.; Chen, P. Lancing Drug Reservoirs into Subcutaneous Fat to Combat Obesity and Associated Metabolic Diseases. Small, 2020, 16(31), e2002872. doi: 10.1002/smll.202002872
  124. Warminski, M.; Kowalska, J.; Jemielity, J. Solid-Phase Synthesis of RNA 5'-Azides and Their Application for Labeling, Ligation, and Cyclization Via Click Chemistry. Current Protocols in Nucleic Acid Chemistry, 2020, 82(1), e112. doi: 10.1002/cpnc.112
  125. Hilger, D.; Kumar, K.K.; Hu, H.; Pedersen, M.F.; O'Brien, E.S.; Giehm, L.; Jennings, C.; Eskici, G.; Inoue, A.; Lerch, M.; Mathiesen, J.M.; Skiniotis, G.; Kobilka, B.K. Structural insights into differences in G protein activation by family A and family B GPCRs. Science, 2020, 369, eaba3373. doi: 10.1126/science.aba3373
  126. Keil, J.M.; Doyle, D.Z.; Qalieh, A.; Lam, M.M.; Funk, O.H.; Qalieh, Y.; Shi, L.; Mohan, N.; Sorel, A.; Kwan, K.Y. Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80. Nature Communications, 2020, 11, 3839. doi: 10.1038/s41467-020-17551-4
  127. Sakhabutdinova, A.R.; Chemeris, A.V.; Garafutdinov, R.R. Enhancement of PCR efficiency using mono- and disaccharides. Analytical Biochemistry, 2020, 606, 113858. doi: 10.1016/j.ab.2020.113858
  128. Liu, L.; Xu, Y.; Zhang, P.; You, J.; Li, W.; Chen, Y.; Li, R.; Rui, B.; Dou, H. High-order Assembly Towards Polysaccharide-Based Complex Coacervate Nanodroplets Capable of Targeting Cancer Cells. Langmuir, 2020, 36(29), 8580–8588. doi: 10.1021/acs.langmuir.0c01458
  129. Chen, X.; Xu, J.; Wong, N.-K.; Zhong, S.; Yang, M.; Liu, Z.; Lu, Y.; Li, W.; Zhou, Y. Chemoproteomic profiling of cobalamin-independent methionine synthases in plant with a covalent probe. Journal of Agricultural and Food Chemistry, 2020, 68(30), 8050–8056. doi: 10.1021/acs.jafc.0c03301
  130. Wang, Y.; Li, L.; Ma, Y.; Tang, Y.; Zhao, Y.; Li, Z.; Pu, W.; Huang, B.; Wen, X.; Cao, X.; Chen, J.; Chen, W.; Zhou, Y.; Zhang, J. A Multifunctional Supramolecular Hydrogel for Prevention of Epidural Adhesion after Laminectomy. ACS Nano, 2020, 14(7), 8202–8219. doi: 10.1021/acsnano.0c01658
  131. Sanman, L.E.; Chen, I.W.; Bieber, J.M.; Thorne, C.A.; Wu, L.F.; Altschuler, S.J. Generation and Quantitative Imaging of Enteroid Monolayers. Methods in Molecular Biology, 2020, 2171, 99–113. doi: 10.1007/978-1-0716-0747-3_6
  132. Lee, S.H.; Park, D.J.; Yun, W.S.; Park, J.-E.; Choi, J.S.; Key, J.; Seo, Y.J. Endocytic trafficking of polymeric clustered superparamagnetic iron oxide nanoparticles in mesenchymal stem cells. Journal of Controlled Release, 2020, 326, 408–418. doi: 10.1016/j.jconrel.2020.07.032
  133. Göbel, M.W.; Bolz, M.; Thomas, L.; Scheffer, U.; Kalden, E.; Hartmann, R.K. Redirection of miRNA-Argonaute Complexes to Specific Target Sites by Synthetic Adaptor Molecules. Chemistry & Biodiversity, 2020, 17(7), e2000272. doi: 10.1002/cbdv.202000272
  134. Gruber, C.G.; Pegoli, A.; Müller, C.; Grätz, L.; She, X.; Keller, M. Differently fluorescence-labelled dibenzodiazepinone-type muscarinic acetylcholine receptor ligands with high M2R affinity. RSC Medicinal Chemistry, 2020, 11(7), 823–832. doi: 10.1039/D0MD00137F
  135. Lim, Y.G.; Kim, H.J.; Kim, J.W.; Park, K. Calcium-binding near-infrared fluorescent nanoprobe for bone tissue imaging. Journal of Industrial and Engineering Chemistry, 2020, 89, 442–447. doi: 10.1016/j.jiec.2020.06.018
  136. Kocere, A.; Resseguier, J.; Wohlmann, J.; Skjeldal, F.M.; Khan, S.; Speth, M.; Dal, N.-J.K.; Ng, M.Y.W.; Alonso-Rodriguez, N.; Scarpa, E.; Rizzello, L.; Battaglia, G.; Griffiths, G.; Fenaroli, F. Real-time imaging of polymersome nanoparticles in zebrafish embryos engrafted with melanoma cancer cells: Localization, toxicity and treatment analysis. EBioMedicine, 2020, 58, 102902. doi: 10.1016/j.ebiom.2020.102902
  137. Shukla, Sourabh and Roe, Anne Jessica and Liu, Ruifu and Veliz, Frank A. and Commandeur, Ulrich and Wald, David N. and Steinmetz, Nicole F. Affinity of plant viral nanoparticle potato virus X (PVX) towards malignant B cells enables cancer drug delivery. Biomaterials Science, 2020, 8(14), 3935–3943. doi: 10.1039/D0BM00683A
  138. Haddad, Y.; Charousova, M.; Zivotska, H.; Splichal, Z.; Merlos Rodrigo, M.A.; Michalkova, H.; Krizkova, S.; Tesarova, B.; Richtera, L.; Vitek, P.; Stokowa-Soltys, K.; Hynek, D.; Milosavljevic, V.; Rex, S.; Heger, Z. Norepinephrine transporter-derived homing peptides enable rapid endocytosis of drug delivery nanovehicles into neuroblastoma cells. Journal of Nanobiotechnology, 2020, 18, 95. doi: 10.1186/s12951-020-00654-x
  139. Yang, J.; Wang, T.; Zhao, L.; Rajasekhar, V.K.; Joshi, S.; Andreou, C.; Pal, S.; Hsu, H.-T.; Zhang, H.; Cohen, I.J.; Huang, R.; Hendrickson, R.C.; Miele, M.M.; Pei, W.; Brendel, M.B.; Healey, J.H.; Chiosis, G.; Kircher, M.F. Gold/alpha-lactalbumin nanoprobes for the imaging and treatment of breast cancer. Nature Biomedical Engineering, 2020, 4, 686–703. doi: 10.1038/s41551-020-0584-z
  140. Martínez-Jothar, L.; Barendrecht, A.D.; de Graaff, A.M.; Oliveira, S.; van Nostrum, C.F.; Schiffelers, R.M.; Hennink, W.E.; Fens, M.H.A.M. Endothelial Cell Targeting by cRGD-Functionalized Polymeric Nanoparticles under Static and Flow Conditions. Nanomaterials, 2020, 10(7), 1353. doi: 10.3390/nano10071353
  141. Zhou, Y.; Zhu, X.; Lin, S.; Zhu, C.; Wu, L.; Chen, R.; Chen, Z.; Li, W. A Novel Nanoparticle Preparation to Enhance the Gastric Adhesion and Bioavailability of Xanthatin. International Journal of Nanomedicine, 2020, 15, 5073–5082. doi: 10.2147/IJN.S252049
  142. Martín-Moreno, A.; Jiménez Blanco, J.L.; Mosher, J.; Swanson, D.R.; García Fernández, J.M.; and Sharma, A.; Ceña, V.; Muñoz-Fernández, M.A. Nanoparticle-Delivered HIV Peptides to Dendritic Cells a Promising Approach to Generate a Therapeutic Vaccine. Pharmaceutics, 2020, 12(7), 656. doi: 10.3390/pharmaceutics12070656
  143. Chetverikov, P.E.; Cvrković, T.; Efimov, P.G.; Klimov, P.B.; Petanović, R.U.; Romanovich, A.E.; Schubert, M.A.; Sukhareva, S.I.; Zukoff, S.N.; Amrine, J. Molecular phylogenetic analyses reveal a deep dichotomy in the conifer-inhabiting genus Trisetacus (Eriophyoidea: Nalepellidae), with the two lineages differing in their female genital morphology and host associations. Experimental and Applied Acarology, 2020, 81(3), 287–316. doi: 10.1007/s10493-020-00503-4
  144. Chen, K.; Yang, R.; Li, Y.; Zhou, J.C.; Zhang, M. Giant ankyrin-B suppresses stochastic collateral axon branching through direct interaction with microtubules. Journal of Cell Biology, 2020, 219(8), e201910053. doi: 10.1083/jcb.201910053
  145. Zhang, N.; Shi, S.; Yoo, B.; Yuan, X.; Li, W.; Zhang, S. 2D-HELS MS Seq: A General LC-MS-Based Method for Direct and de novo Sequencing of RNA Mixtures with Different Nucleotide Modifications. Journal of Visualized Experiments, 2020, e61281. doi: 10.3791/61281
  146. Kim, S.; Kang, S.H.; Byun, S.H.; Kim, H.-J.; Park, I.-K.; Hirschberg, H.; Hong, S.J. Intercellular Bioimaging and Biodistribution of Gold Nanoparticle-Loaded Macrophages for Targeted Drug Delivery. Electronics, 2020, 9(7), 1105. doi: 10.3390/electronics9071105
  147. Camardo, A.; Carney, S.; Ramamurthi, A. Assessing the targeting and fate of cathepsin k antibody-modified nanoparticles in a rat abdominal aortic aneurysm model. Acta Biomaterialia, 2020, 112, 225–233. doi: 10.1016/j.actbio.2020.05.037
  148. Crawford, B.; Wang, H.-N.; Strobbia, P.; Zentella, R.; Pei, Z.-M.; Sun, T.-P.; Vo-Dinh, T. Plasmonic Nanobiosensing: from in situ plant monitoring to cancer diagnostics at the point of care. Journal of Physics: Photonics, 2020, 2(3), 034012. doi: 10.1088/2515-7647/ab9714
  149. Kim, D.; Singh, N.; Waldemer-Streyer, R.J.; Yoon, M.-S.; Chen, J. Muscle-derived TRAIL negatively regulates myogenic differentiation. Experimental Cell Research, 2020, 394(1), 112165. doi: 10.1016/j.yexcr.2020.112165
  150. Tolentino, M.Q.; Hartmann, A.K.; Loe, D.T.; Rouge, J.L. Controlled release of small molecules and proteins from DNA-surfactant stabilized metal organic frameworks. Journal of Materials Chemistry B, 2020, 8(26), 5627–5635. doi: 10.1039/d0tb00767f
  151. Cao, C.; Chen, F.; Garvey, C.J.; Stenzel, M.H. Drug-directed morphology changes in polymerization induced self-assembly (PISA) influences the biological behavior of nanoparticles. ACS Applied Materials & Interfaces, 2020, 12(27), 30221–30233. doi: 10.1021/acsami.0c09054
  152. Srinageshwar, B.; Florendo, M.; Clark, B.; Johnson, K.; Munro, N.; Peruzzaro, S.; Antcliff, A.; Andrews, M.; Figacz, A.; Swanson, D.; Dunbar, G.L.; Sharma, A.; Rossignol, J. A Mixed-Surface Polyamidoamine Dendrimer for In Vitro and In Vivo Delivery of Large Plasmids. Pharmaceutics, 2020, 12(7), 619. doi: 10.3390/pharmaceutics12070619
  153. Feng, C.; Ouyang, J.; Tang, Z.; Kong, N.; Liu, Y.; Fu, L.; Ji, X.; Xie, T.; Farokhzad, O.C.; Tao, W. Germanene-Based Theranostic Materials for Surgical Adjuvant Treatment: Inhibiting Tumor Recurrence and Wound Infection. Matter, 2020, 3(1), 127–144. doi: 10.1016/j.matt.2020.04.022
  154. Seo, J.-H.; Lee, S.Y.; Hwang, C.; Yang, M.; Lee, J.; Lee, S.-H.; Cho, H.-J. Multi-layered cellulose nanocrystal system for CD44 receptor-positive tumor-targeted anticancer drug delivery. International Journal of Biological Macromolecules, 2020, 162, 798–809. doi: 10.1016/j.ijbiomac.2020.06.193
  155. Hahn, F.; Niesar, A.; Wangen, C.; Wild, M.; Grau, B.; Herrmann, L.; Capci, A.; Adrait, A.; Couté, Y.; Tsogoeva, S.B.; Marschall, M. Target verification of artesunate-related antiviral drugs: assessing the role of mitochondrial and regulatory proteins by click chemistry and fluorescence labeling. Antiviral Research, 2020, 180, 104861. doi: 10.1016/j.antiviral.2020.104861
  156. Aronsson, C.; Jury, M.; Naeimipour, S.; Rasti Boroojeni, F.; Christoffersson, J.; Lifwergren, P.; Mandenius, C.-F.; Selegård, R.; Aili, D. Dynamic peptide-folding mediated biofunctionalization and modulation of hydrogels for 4D bioprinting. Biofabrication, 2020, 12(3), 035031. doi: 10.1088/1758-5090/ab9490
  157. Kleinpenning, F.; Steigenberger, B.; Wu, W.; Heck, A.J.R. Fishing for newly synthesized proteins with phosphonate-handles. Nature Communications, 2020, 11, 3244. doi: 10.1038/s41467-020-17010-0
  158. Luo, K.; Guo, W.; Yu, Y.; Xu, S.; Zhou, M.; Xiang, K.; Niu, K.; Zhu, X.; Zhu, G.; An, Z.; Yu, Q.; Gan, Z. Reduction-sensitive platinum (IV)-prodrug nano-sensitizer with an ultra-high drug loading for efficient chemo-radiotherapy of Pt-resistant cervical cancer in vivo. Journal of Controlled Release, 2020, 326, 25–37. doi: 10.1016/j.jconrel.2020.06.005
  159. Novoselova, M.V.; Abakumova, T.O.; Khlebtsov, B.N.; Zatsepin, T.S.; Lazareva, E.N.; Tuchin, V.V.; Zharov, V.P.; Gorin, D.A.; Galanzha, E.I. Optical clearing for photoacoustic lympho- and angiography beyond conventional depth limit in vivo. Photoacoustics, 2020, 20, 100186. doi: 10.1016/j.pacs.2020.100186
  160. Pink, M.; Verma, N.; Schmitz-Spanke, S. Benchmark dose analyses of toxic endpoints in lung cells provide sensitivity and toxicity ranking across metal oxide nanoparticles and give insights into the mode of action. Toxicology Letters, 2020, 331, 218–226. doi: 10.1016/j.toxlet.2020.06.012
  161. Sokolova, V.; Nzou, G.; van der Meer, S.B.; Ruks, T.; Heggen, M.; Loza, K.; Hagemann, N.; Murke, F.; Giebel, B.; Hermann, D.M.; Atala, A.J.; Epple, M. Ultrasmall gold nanoparticles (2 nm) can penetrate and enter cell nuclei in an in vitro 3D brain spheroid model. Acta Biomaterialia, 2020, 111, 349–362. doi: 10.1016/j.actbio.2020.04.023
  162. Nemec, A.A.; Tomko, R.J. A suite of PCR-based peptide tagging plasmids to permit epitope-targeted enzymatic functionalization of yeast proteins. Yeast, 2020, 37(5–6), 327–335. doi: 10.1002/yea.3471
  163. Xu, J.; Guo, J.; Golob-Schwarzl, N.; Haybaeck, J.; Qiu, X.; Hildebrandt, N. Single-measurement multiplexed quantification of microRNAs from human tissue using catalytic hairpin assembly and Förster resonance energy transfer. ACS Sensors, 2020, 5(6), 1768–1776. doi: 10.1021/acssensors.0c00432
  164. He, Y.; Ren, E.; Lu, Z.; Chen, H.; Qin, Z.; Wang, J.; He, M.; Liu, G.; Zheng, L.; Zhao, J. Rational engineering of ferritin Nanocages for targeted therapy of osteoarthritis. Nanomedicine, 2020, 28, in press. doi: 10.1016/j.nano.2020.102210
  165. Rojas-Sánchez, L.; Loza, K.; Epple, M. Synthesis and intracellular tracing surface-functionalized calcium phosphate nanoparticles by super-resolution microscopy (STORM). Materialia, 2020, 12, 100773. doi: 10.1016/j.mtla.2020.100773
  166. Phung, C.D.; Le, T.G.; Nguyen, V.H.; Vu, T.T.; Nguyen, H.Q.; Kim, J.O.; Yong, C.S.; Nguyen, C.N. PEGylated-Paclitaxel and Dihydroartemisinin Nanoparticles for Simultaneously Delivering Paclitaxel and Dihydroartemisinin to Colorectal Cancer. Pharmaceutical Research, 2020, 37, 129. doi: 10.1007/s11095-020-02819-7
  167. Bai, M.; Cao, X.; Huang, W.; Chen, F.; Zhao, Y.; Xue, J.; Li, Y.; Cheng, Y.; Zhang, L.; Zhao, Y. Visualizing Newly Synthesized RNA by Bioorthogonal Labeling-primed DNA Amplification. Analytical Chemistry, 2020, 92(12), 8444–8449. doi: 10.1021/acs.analchem.0c01161
  168. Safari, H.; Kelley, W.J.; Saito, E.; Kaczorowski, N.; Carethers, L.; Shea, L.D.; Eniola-Adefeso, O. Neutrophils preferentially phagocytose elongated particles {\textendash} An opportunity for selective targeting in acute inflammatory diseases. Science Advances, 2020, 6(24), eaba1474. doi: 10.1126/sciadv.aba1474
  169. Priwitaningrum, D.L.; Jentsch, J.; Bansal, R.; Rahimian, S.; Storm, G.; Hennink, W.E.; Prakash, J. Apoptosis-inducing Peptide Loaded in PLGA Nanoparticles Induces Anti-tumor Effects in vivo. International Journal of Pharmaceutics, 2020, 585, 119535. doi: 10.1016/j.ijpharm.2020.119535
  170. Emaus, M.N.; Anderson, J.L. Allelic discrimination between circulating tumor DNA fragments enabled by a multiplex-qPCR assay containing DNA-enriched magnetic ionic liquids. Analytica Chimica Acta, 2020, 1124, 184–193. doi: 10.1016/j.aca.2020.04.078
  171. Arraf, A.A.; Yelin, R.; Reshef, I.; Jadon, J.; Abboud, M.; Zaher, M.; Schneider, J.; Vladimirov, F.K.; Schultheiss, T.M. Hedgehog Signaling Regulates Epithelial Morphogenesis to Position the Ventral Embryonic Midline. Developmental Cell, 2020, 53(5), 589–602.e6. doi: 10.1016/j.devcel.2020.04.016
  172. Vora, P.; Venugopal, C.; Salim, S.K.; Tatari, N.; Bakhshinyan, D.; Singh, M.; Seyfrid, M.; Upreti, D.; Rentas, S.; Wong, N.; Williams, R.; Qazi, M.A.; Chokshi, C.; Ding, A.; Subapanditha, M.; Savage, N.; Mahendram, S.; Ford, E.; Adile, A.A.; McKenna, D.; McFarlane, N.; Huynh, V.; Wylie, R.G.; Pan, J.; Bramson, J.; Hope, K.; Moffat, J.; Singh, S. The Rational Development of CD133-Targeting Immunotherapies for Glioblastoma. Cell Stem Cell, 2020, 26(6), 832–844.e6. doi: 10.1016/j.stem.2020.04.008
  173. Bhattacharya, D.S.; Svechkarev, D.A.; Bapat, A.; Patil, P.; Hollingsworth, M.A.; Mohs, A.M. Sulfation modulates the targeting properties of hyaluronic acid to P-selectin and CD44. ACS Biomaterials Science & Engineering, 2020, 6(6), 3585–3598. doi: 10.1021/acsbiomaterials.0c00115
  174. Ridolfo, R.; Arends, J.J.; van Hest, J.C.M.; Williams, D.S. Worm-like nanovector with enhanced drug loading using blends of biodegradable block copolymers. Biomacromolecules, 2020, 21(6), 2199–2207. doi: 10.1021/acs.biomac.0c00169
  175. Zhao, Y.; Fletcher, N.L.; Gemmell, A.; Houston, Z.H.; Howard, C.B.; Blakey, I.; Liu, T.; Thurecht, K.J. Investigation of the Therapeutic Potential of a Synergistic Delivery System through Dual Controlled Release of Camptothecin–Doxorubicin. Advanced Therapeutics, 2020, 3(6), 1900202. doi: 10.1002/adtp.201900202
  176. Mayorova, O.A.; Sindeeva, O.A.; Lomova, M.V.; Gusliakov, O.I.; Tarakanchikova, Y.V.; Tyutyaev, E.V.; Pinyaev, S.I.; Kulikov, O.A.; German, S.V.; Pyataev, N.A.; Gorin, D.A.; Sukhorukov, G.B. Endovascular addressing improves the effectiveness of magnetic targeting of drug carrier. Comparison with the conventional administration method. Nanomedicine, 2020, 28, 102184. doi: 10.1016/j.nano.2020.102184
  177. Palumbo, C.M.; Gutierrez-Bujari, J.M.; O'Geen, H.; Segal, D.J.; Beal, P. Versatile 3' Functionalization of CRISPR Single Guide RNA. ChemBioChem, 2020, 21(11), 1633–1640. doi: 10.1002/cbic.201900736
  178. Hellyer, S.D.; Aggarwal, S.; Chen, A.N.; Leach, K.; Lapinsky, D.J.; Gregory, K.J. Development of Clickable Photoaffinity Ligands for Metabotropic Glutamate Receptor 2 Based on Two Positive Allosteric Modulator Chemotypes. ACS Chemical Neuroscience, 2020, 11(11), 1597–1609. doi: 10.1021/acschemneuro.0c00009
  179. Moutsiopoulou, A.; Broyles, D.; Joda, H.; Dikici, E.; Kaur, A.; Kaifer, A.E.; Daunert, S.; Deo, S.K. Bioluminescent Protein-Inhibitor Pair in the Design of a Molecular Aptamer Beacon Biosensing System. Analytical Chemistry, 2020, 92(11), 7393–7398. doi: 10.1021/acs.analchem.0c00518
  180. Shunatova, N.; Borisenko, I. Proliferating activity in a bryozoan lophophore. PeerJ, 2020, 8, e9179. doi: 10.7717/peerj.9179
  181. Alfaifi, A.A.; Heyder, R.S.; Bielski, E.R.; Almuqbil, R.M.; Kavdia, M.; Gerk, P.M.; da Rocha, S.R.P. Megalin-targeting liposomes for placental drug delivery. Journal of Controlled Release, 2020, 324, 366–378. doi: 10.1016/j.jconrel.2020.05.033
  182. Möltgen, S.; Piumatti, E.; Massafra, G.M.; Metzger, S.; Jaehde, U.; Kalayda, G.V. Cisplatin Protein Binding Partners and Their Relevance for Platinum Drug Sensitivity. Cells, 2020, 9, 1322. doi: 10.3390/cells9061322
  183. Gonzales, J.; Pirovano, G.; Chow, C.Y.; de Souza Franca, P.D.; Carter, L.M.; Klint, J.K.; Guru, N.; Lewis, J.S.; King, G.F.; Reiner, T. Fluorescence labeling of a Nav1.7-targeted peptide for near-infrared nerve visualization. EJNMMI Research, 2020, 10, 49. doi: 10.1186/s13550-020-00630-4
  184. Matoori, S.; Mooney, D.J. Near-Infrared Fluorescence Hydrogen Peroxide Assay for Versatile Metabolite Biosensing in Whole Blood. Small, 2020, 16(20), 2000369. doi: 10.1002/smll.202000369
  185. Wang, C.; Fernández de Ávila, B.E.; Mundaca-Uribe, R.; Lopez-Ramirez, M.A.; Ramírez-Herrera, D.E.; Shukla, S.; Steinmetz, N.F.; Wang, J. Active Delivery of VLPs Promotes Anti-Tumor Activity in a Mouse Ovarian Tumor Model. Small, 2020, 16(20), e1907150. doi: 10.1002/smll.201907150
  186. Levada, K.; Pshenichnikov, S.; Omelyanchik, A.; Rodionova, V.; Nikitin, A.; Savchenko, A.; Schetinin, I.; Zhukov, D.; Abakumov, M.; Majouga, A.; Lunova, M.; Jirsa, M.; Smolková, B.; Uzhytchak, M.; Dejneka, A.; Lunov, O. Progressive lysosomal membrane permeabilization induced by iron oxide nanoparticles drives hepatic cell autophagy and apoptosis. Nano Convergence, 2020, 7, 17. doi: 10.1186/s40580-020-00228-5
  187. Sheshachala, S.; Grösche, M.; Scherr, T.; Hu, Y.; Sun, P.; Bartschat, A.; Mikut, R; Niemeyer, C.M. Segregation of dispersed silica nanoparticles in microfluidic water in oil droplets: A kinetic study. ChemPhysChem, 2020, 21(10), 1070–1078. doi: 10.1002/cphc.201901151
  188. Reed, S.A.; Brzovic, D.A.; Takasaki, S.S.; Boyko, K.V.; Antos, J.M. Efficient Sortase-Mediated Ligation Using a Common C-Terminal Fusion Tag. Bioconjugate Chemistry, 2020, 31(5), 1463–1473. doi: 10.1021/acs.bioconjchem.0c00156
  189. Deng, L.; Huang, X.; Ren, J. In Situ Study of the Drug-target Protein Interaction in Single Living Cells by Combining Fluorescence Correlation Spectroscopy with Affinity Probes. Analytical Chemistry, 2020, 92(10), 7020–7027. doi: 10.1021/acs.analchem.0c00263
  190. Strobbia, P.; Odion, R.A.; Maiwald, M.; Sumpf, B.; Vo-Dinh, T. Direct SERDS sensing of molecular biomarkers in plants under field conditions. Analytical and Bioanalytical Chemistry, 2020, 412(14), 3457–3466. doi: 10.1007/s00216-020-02544-5
  191. Wang, J.; Li, Y.; Li, L.; Yang, J.; Kopeček, J. Exploration and Evaluation of Therapeutic Efficacy of Drug-Free Macromolecular Therapeutics in Collagen-Induced Rheumatoid Arthritis Mouse Model. Macromolecular Bioscience, 2020, 20(5), e1900445. doi: 10.1002/mabi.201900445
  192. Xu, N.; Yang, Y.-F.; Chen, L.; Lin, J. A Ferritin–Albumin–Cu Nanoparticle that Efficaciously Delivers Copper(II) Ions to a Tumor and Improves the Therapeutic Efficacy of Disulfiram. ACS Omega, 2020, 5(18), 10415–10422. doi: 10.1021/acsomega.0c00293
  193. Wang, S.P.; Cao, S.; Arhatte, M.; Li, D.; Shi, Y.; Kurz, S.; Hu, J.; Wang, L.; Shao, J.; Atzberger, A.; Wang, Z.; Wang, C.; Zang, W.; Fleming, I.; Wettschureck, N:, Honoré, E.; Offermanns, S. Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice. Nature Communications, 2020, 11, 2303. doi: 10.1038/s41467-020-16026-w
  194. Rodríguez-Hakim, M.; Anand, S.; Tajuelo, J.; Yao, Z.; Kannan, A.; Fuller, G.G. Asphaltene-induced spontaneous emulsification: Effects of interfacial co-adsorption and viscoelasticity. Journal of Rheology, 2020, 64(4), 799–816. doi: 10.1122/1.5145307
  195. Korzhikov-Vlakh, V.; Katernuk, I.; Pilipenko, I.; Lavrentieva, A.; Guryanov, I.; Sharoyko, V.; Manshina, A.A.; Tennikova, T.B. Photosensitive Poly-L-lysine/Heparin Interpolyelectrolyte Complexes for Delivery of Genetic Drugs. Polymers, 2020, 12(5), 1077. doi: 10.3390/polym12051077
  196. Radman, S.; Raić, S.; Bućan, I.; Pribisalić, A.; Dunatov, J.; Mudnić, I.; Boban, M.; Pellay, F.X.; Kolčić, I.; Polašek, O. Searching for carbonylome biomarkers of aging – development and validation of the proteomic method for quantification of carbonylated protein in human plasma. Croatian Medical Journal, 2020, 61(2), 119–125. doi: 10.3325/cmj.2020.61.119
  197. Monteiro, P.F.; Gulfam, M.; Monteiro, C.J.; Travanut, A.; Abelha, T.F.; Pearce, A.K.; Jerôme, C.; Grabowska, A.M.; Clarke, P.A.; Collins, H.M.; Heery, D.M.; Gershkovich, P.; Alexander, C. Synthesis of micellar-like terpolymer nanoparticles with reductively-cleavable cross-links and evaluation of efficacy in 2D and 3D models of triple negative breast cancer. Journal of Controlled Release, 2020, 323, 549–564. doi: 10.1016/j.jconrel.2020.04.049
  198. Sabeti Azad, M.; Okuda, M.; Cyrenne, M.; Bourge, M.; Heck, M.-P.; Yoshizawa, S.; Fourmy, D. Fluorescent Aminoglycoside Antibiotics and Methods for Accurately Monitoring Uptake by Bacteria. ACS Infectious Diseases, 2020, 6(5), 1008–1017. doi: 10.1021/acsinfecdis.9b00421
  199. Alberg, I.; Kramer, S.; Schinnerer, M.; Hu, Q.; Seidl, C.; Leps, C.; Drude, N.; Möckel, D.; Rijcken, C.; Lammers, T.; Diken, M.; Maskos, M.; Morsbach, S.; Landfester, K.; Tenzer, S.; Barz, M.; Zentel, R. Polymeric Nanoparticles with Neglectable Protein Corona. Small, 2020, 16(18), 1907574. doi: 10.1002/smll.201907574
  200. Syga, L.; De Vries, R.H.; van Oosterhout, H.; Bartelds, R.; Boersma, A.J.; Roelfes, G.; Poolman, B. A trifunctional linker for palmitoylation and peptide and protein localization in biological membranes. ChemBioChem, 2020, 21(9), 1320–1328. doi: 10.1002/cbic.201900655
  201. Ko, Y.J.; Lee, J.W.; Kim, H.; Cho, E.; Yang, Y.; Kim, I.-S.; Kim, S.H.; Kwon, I.C. Versatile activatable vSIRPα-probe for cancer-targeted imaging and macrophage-mediated phagocytosis of cancer cells. Journal of Controlled Release, 2020, 323, 376–386. doi: 10.1016/j.jconrel.2020.04.037
  202. Leonard, D.; Huang, W.; Izadmehr, S.; O'Connor, C.M.; Wiredja, D.D.; Wang, Z.; Zaware, N.; Chen, Y.; Schlatzer, D.M.; Kiselar, J.; Vasireddi, N.; Schüchner, S.; Perl, A.L.; Galsky, M.D.; Xu, W.; Brautigan, D.L.; Ogris, E.; Taylor, D.J.; Narla, G. Selective PP2A Enhancement through Biased Heterotrimer Stabilization. Cell, 2020, 181(3), 688–701.e16. doi: 10.1016/j.cell.2020.03.038
  203. Chen, Y.; Shen, W.; Tang, C.; Huang, J.; Fan, C.; Yin, Z.; Hu, Y.; Chen, W.; Ouyang, H.; Zhou, Y.; Mao, Z.; Chen, X. Targeted pathological collagen delivery of sustained-release rapamycin to prevent heterotopic ossification. Science Advances, 2020, 6(18), eaay9526. doi: 10.1126/sciadv.aay9526
  204. von Döhren, J.; Kuhl, S. A simple method for long-term vital-staining of ciliated epidermal cells in aquatic larvae. Journal of Biological Methods, 2020, 7(2), e132. doi: 10.14440/jbm.2020.320
  205. Bao, X.; Qian, K.; Yao, P. Oral delivery of exenatide-loaded hybrid zein nanoparticles for stable blood glucose control and β-cell repair of type 2 diabetes mice. Journal of Nanobiotechnology, 2020, 18, 67. doi: 10.1186/s12951-020-00619-0
  206. Cioloboc, D.; Kurtz, D.M. Targeted cancer cell delivery of arsenate as a reductively activated prodrug. Journal of Biological Inorganic Chemistry, 2020, 25(3), 441–449. doi: 10.1007/s00775-020-01774-3
  207. Cutie, S.; Payumo, A.Y.; Lunn, D.; Huang, G.N. In vitro and in vivo roles of glucocorticoid and vitamin D receptors in the control of neonatal cardiomyocyte proliferative potential. Journal of Molecular and Cellular Cardiology, 2020, 142, 126–134. doi: 10.1016/j.yjmcc.2020.04.013
  208. Zaytsev, S.M.; Svenskaya, Y.I.; Lengert, E.V.; Terentyuk, G.S.; Bashkatov, A.N.; Tuchin, V.V.; Genina, E.A. Optimized skin optical clearing for Optical Coherence Tomography monitoring of encapsulated drug delivery through the hair follicles. Journal of Biophotonics, 2020, 13(4), e201960020. doi: 10.1002/jbio.201960020
  209. Yoshikawa, T.; Quoc Phan, K.; Tagawa, H.; Sasaki, K.; Feng, H.; Kishimura, A.; Mori, T.; Katayama, Y. Modification of nitric oxide donors onto a monoclonal antibody boosts accumulation in solid tumors. International Journal of Pharmaceutics, 2020, 583, 119352. doi: 10.1016/j.ijpharm.2020.119352
  210. Fodor-Kardos, A.; Kiss, Á.F.; Monostory, K.; Feczkó, T. Sustained in vitro interferon-beta release and in vivo toxicity of PLGA and PEG-PLGA nanoparticles. RSC Advances, 2020, 10(27), 15893–15900. doi: 10.1039/c9ra09928j
  211. Chen, Q.; Gao, M.; Li, Z.; Xiao, Y.; Bai, X.; Boakye-Yiadom, K.O.; Xu, X.; Zhang, X.-Q. Biodegradable nanoparticles decorated with different carbohydrates for efficient macrophage-targeted gene therapy. Journal of Controlled Release, 2020, 323, 179–190. doi: 10.1016/j.jconrel.2020.03.044
  212. Walker, J.A.T.; Wang, X.; Peter, K.; Kempe, K.; Corrie, S.R. Dynamic solid-state ultrasound contrast agent for monitoring pH fluctuations in vivo. ACS Sensors, 2020, 5(4), 1190–1197. doi: 10.1021/acssensors.0c00245
  213. Ren, J.; Yin, X.; Chen, Y.; Chen, Y.; Su, H.; Wang, K.; Zhang, L.; Zhu, J.; Zhang, C. Alginate hydrogel-coated syringe needles for rapid haemostasis of vessel and viscera puncture. Biomaterials, 2020, 249, 120019. doi: 10.1016/j.biomaterials.2020.120019
  214. Guo, H.; Song, S.; Dai, T.; Sun, K.; Zhou, G.; Li, M.; Mann, S.; Dou, H. Near-Infrared Fluorescent and Magnetic Resonance Dual-Imaging Coacervate Nanoprobes for Trypsin Mapping and Targeted Payload Delivery of Malignant Tumors. ACS Applied Materials & Interfaces, 2020, 12(15), 17302–17313. doi: 10.1021/acsami.0c03433
  215. Schwegmann, K.; Hohn, M.; Hermann, S.; Schäfers, M.; Riemann, B.; Haufe, G.; Wagner, S.; Breyholz, H.-J. Optimizing the biodistribution of radiofluorinated barbiturate tracers for MMP imaging by introduction of fluorescent dyes as pharmacokinetic modulators. Bioconjugate Chemistry, 2020, 31(4), 1117–1132. doi: 10.1021/acs.bioconjchem.9b00817
  216. Ryu, J.S.; Im, S.H.; Kang, Y.K.; Kim, Y.S.; Chung, H.J. Ultra-fast and universal detection of Gram-negative bacteria in complex samples based on colistin derivatives. Biomaterials Science, 2020, 8(8), 2111–2119. doi: 10.1039/c9bm01926j
  217. Mindubaev, A.Z.; Kuznetsova, S.V.; Evtyugin, V.G.; Daminova, A.G.; Grigoryeva, T.V.; Romanova, Y.D.; Romanova, V.A.; Babaev, V.M.; Buzyurova, D.N.; Babynin, E.V.; Badeeva, E.K.; Minzanova, S.T.; Mironova, L.G. Effect of White Phosphorus on the Survival, Cellular Morphology, and Proteome of Aspergillus niger. Applied Biochemistry and Microbiology, 2020, 56(2), 194–201. doi: 10.1134/S0003683820020118
  218. Liu, Y.; Fens, M.H.A.M.; Lou, B.; van Kronenburg, N.C.H.; Maas-Bakker, R.F.M.; Kok, R.J.; Oliveira, S.; Hennink, W.E.; van Nostrum, C.F. π-π-Stacked Poly(ε-caprolactone)-b-poly(ethylene glycol) Micelles Loaded with a Photosensitizer for Photodynamic Therapy. Pharmaceutics, 2020, 12(4), 338. doi: 10.3390/pharmaceutics12040338
  219. Jiang, S.; Mottola, M.; Han, S.; Thiramanas, R.; Graf, R.; Lieberwirth, I.; Mailänder, V.; Crespy, D.; Landfester, K. Versatile Preparation of Silica Nanocapsules for Biomedical Applications. Particle & Particle Systems Characterization, 2020, 37(4), 1900484. doi: 10.1002/ppsc.201900484
  220. Taipaleenmäki, E.; Christensen, G.; Brodszkij, E.; Mouritzen, S.A.; Gal, N.; Madsen, S.; Hedemann, M.S.; Knudsen, T.A.; Jensen, H.M.; Christiansen, S.L.; Sparsø, F.V.; Städler, B. Mucopenetrating polymer - Lipid hybrid nanovesicles as subunits in alginate beads as an oral formulation. Journal of Controlled Release, 2020, 322, 470–485. doi: 10.1016/j.jconrel.2020.03.047
  221. Qiu, J.; Li, X.; Steenkeste, K.; Barroca-Aubry, N.; Aymes-Chodur, C.; Roger, P.; Casas-Solvas, J.M.; Vargas-Berenguel, A.; Rihouey, C.; Picton, L.; Gref, R. Self-assembled multifunctional core-shell highly porous metal-organic framework nanoparticles. International Journal of Pharmaceutics, 2020, 581, 119281. doi: 10.1016/j.ijpharm.2020.119281
  222. Terekhov, S.S.; Nazarov, A.S.; Mokrushina, Y.A.; Baranova, M.N.; Potapova, N.A.; Malakhova, M.V.; Ilina, E.N.; Smirnov, I.V.; Gabibov, A.G. Deep Functional Profiling Facilitates the Evaluation of the Antibacterial Potential of the Antibiotic Amicoumacin. Antibiotics, 2020, 9(4), 157. doi: 10.3390/antibiotics9040157
  223. Sagert, L.; Hennig, F.; Thomas, C.; Tampé, R. A loop structure allows TAPBPR to exert its dual function as MHC I chaperone and peptide editor. eLife, 2020, 9, e55326. doi: 10.7554/eLife.55326
  224. Liu, Y.; Scrivano, L.; Peterson, J.D.; Fens, M.H.A.M.; Beltrán Hernández, I.; Mesquita, B.; Sastre Torano, J.; Hennink, W.E.; van Nostrum, C.F.; Oliveira, S. EGFR targeted nanobody functionalized polymeric micelles loaded with mTHPC for selective photodynamic therapy. Molecular Pharmaceutics, 2020, 17(4), 1276–1292. doi: 10.1021/acs.molpharmaceut.9b01280
  225. Al-Lawati, H.; Vakili, M.R.; Lavasanifar, A.; Ahmed, S.; Jamali, F. Reduced heart exposure of diclofenac by its polymeric micellar formulation, normalizes CYP- mediated metabolism of arachidonic acid imbalance in adjuvant arthritis rat model: Implications in reduced cardiovascular side effects of diclofenac by ... Molecular Pharmaceutics, 2020, 17(4), 1377–1386. doi: 10.1021/acs.molpharmaceut.0c00069
  226. Li, Q.; Wang, F.; Yang, J.; Liu, D. Direct cytoplasm delivery of gold nanoparticles for real-time apoptosis detection. Nano Research, 2020, 13(3), 853–860. doi: 10.1007/s12274-020-2707-y
  227. Shukla, S.; Wang, C.; Beiss, V.; Steinmetz, N.F. Antibody Response against Cowpea Mosaic Viral Nanoparticles Improves In Situ Vaccine Efficacy in Ovarian Cancer. ACS Nano, 2020, 14(3), 2994–3003. doi: 10.1021/acsnano.9b07865
  228. Jordan, T.; O’Brien, M.A.; Spatarelu, C.-P.; Luke, G.P. Antibody-Conjugated Barium Titanate Nanoparticles for Cell-Specific Targeting. ACS Applied Nano Materials, 2020, 3(3), 2636–2646. doi: 10.1021/acsanm.0c00019
  229. Kołt, S.; Janiszewski, T.; Kaiserman, D.; Modrzycka, S.; Snipas, S.J.; Salvesen, G.; Dra G, M.; Bird, P.I.; Kasperkiewicz, P. Detection of Active Granzyme A in NK92 Cells with Fluorescent Activity-Based Probe. Journal of Medicinal Chemistry, 2020, 63(6), 3359–3369. doi: 10.1021/acs.jmedchem.9b02042
  230. Peeler, D.J.; Luera, N.; Horner, P.J.; Pun, S.H.; Sellers, D.L. Polyplex transfection from intracerebroventricular delivery is not significantly affected by traumatic brain injury. Journal of Controlled Release, 2020, 322, 149–156. doi: 10.1016/j.jconrel.2020.03.025
  231. Zhang, E.; Zhukova, V.; Semyonkin, A.; Osipova, N.; Malinovskaya, Y.; Maksimenko, O.; Chernikov, V.; Sokolov, M.; Grigartzik, L.; Sabel, B.A.; Gelperina, S.; Henrich-Noack, P. Release kinetics of fluorescent dyes from PLGA nanoparticles in retinal blood vessels: in vivo monitoring and ex vivo localization. European Journal of Pharmaceutics and Biopharmaceutics, 2020, 150, 131–142. doi: 10.1016/j.ejpb.2020.03.006
  232. Yu, Y.; Guo, Y.; Tian, Q.; Lan, Y.; Yeh, H.; Zhang, M.; Tasan, I.; Jain, S.; Zhao, H. An efficient gene knock-in strategy using 5'-modified double-stranded DNA donors with short homology arms. Nature Chemical Biology, 2020, 16(4), 387–390. doi: 10.1038/s41589-019-0432-1
  233. Qi, B.; Crawford, A.J.; Wojtynek, N.E.; Talmon, G.A.; Hollingsworth, M.A.; Ly, Q.P.; Mohs, A.M. Tuned near infrared fluorescent hyaluronic acid conjugates for delivery to pancreatic cancer for intraoperative imaging. Theranostics, 2020, 10(8), 3413–3429. doi: 10.7150/thno.40688
  234. Pfister, J.; Summer, D.; Petrik, M.; Khoylou, M.; Lichius, A.; Kaeopookum, P.; Kochinke, L.; Orasch, T.; Haas, H.; Decristoforo, C. Hybrid Imaging of Aspergillus fumigatus Pulmonary Infection with Fluorescent, 68Ga-Labelled Siderophores. Biomolecules, 2020, 10, 168. doi: 10.3390/biom10020168
  235. Tan, M.S.Y.; Davison, D.; Sanchez, M.I.; Anderson, B.M.; Howell, S.; Snijders, A.; Edgington-Mitchell, L.E.; Deu, E. Novel broad-spectrum activity-based probes to profile malarial cysteine proteases. PLoS One, 2020, 15(1), e0227341. doi: 10.1371/journal.pone.0227341
  236. Zhong, Y.; Sun, R.; Geng, Y.; Zhou, Q.; Piao, Y.; Xie, T.; Zhou, R.; Shen, Y. N-Oxide polymer-cupric ion nanogels potentiate disulfiram for cancer therapy. Biomaterials Science, 2020, 8(6), 1726–1733. doi: 10.1039/c9bm01841g
  237. Zhang, Y.; García-Gabilondo, M.; Grayston, A.; Feiner, I.V.J.; Anton-Sales, I.; Loiola, R.A.; Llop, J.; Ramos-Cabrer, P.; Barba, I:; Garcia-Dorado, D.; Gosselet, F.; Rosell, A.; Roig, A. PLGA protein nanocarriers with tailor-made fluorescence/MRI/PET imaging modalities. Nanoscale, 2020, 12(8), 4988–5002. doi: 10.1039/c9nr10620k
  238. Beri, D.; Jakoby, M.; Howard, I.A.; Busko, D.; Richards, B.S.; Turshatov, A. Improved photon absorption in dye-functionalized silicon nanocrystals synthesized via microwave-assisted hydrosilylation. Dalton Transactions, 2020, 49(7), 2290–2299. doi: 10.1039/c9dt04497c
  239. Jiang, S.; Prozeller, D.; Pereira, J.; Simon, J.; Han, S.; Wirsching, S.; Fichter, M.; Mottola, M.; Lieberwirth, I.; Morsbach, S.; Mailänder, V.; Gehring, S.; Crespy, D.; Landfester, K. Controlling protein interactions in blood for effective liver immunosuppressive therapy by silica nanocapsules. Nanoscale, 2020, 12(4), 2626–2637. doi: 10.1039/c9nr09879h
  240. Maklakova, S.Y.; Naumenko, V.A.; Chuprov, A.D.; Mazhuga, M.P.; Zyk, N.V.; Beloglazkina, E.K.; Majouga, A.G. Cellular uptake of N-acetyl-d-galactosamine-, N-acetyl-d-glucosamine- and d-mannose-containing fluorescent glycoconjugates investigated by liver intravital microscopy. Carbohydrate Research, 2020, 489, 107928. doi: 10.1016/j.carres.2020.107928
  241. Kwon, S.-H.; Wi, T.; Park, Y.I.; Kim, M.W.; Lee, G.; Higaki, T.; Choi, J.H.; Lee, R. Non-invasive early detection of calpain 2-enriched non-small cell lung cancer using a human serum albumin-bounded calpain 2 nanosensor. Bioconjugate Chemistry, 2020, 31(3), 803–812. doi: 10.1021/acs.bioconjchem.9b00870
  242. Wouters, S.; Vugs, W.; Arts, R.; de Leeuw, N.; Teeuwen, R.; Merkx, M. Bioluminescent antibodies through photoconjugation of protein-G-luciferase fusion proteins. Bioconjugate Chemistry, 2020, 31(3), 656–662. doi: 10.1021/acs.bioconjchem.9b00804
  243. Yamada, K.J.; Heim, C.E.; Xi, X.; Attri, K.S.; Wang, D.; Zhang, W.; Singh, P.K.; Bronich, T.K.; Kielian, T. Monocyte metabolic reprogramming promotes pro-inflammatory activity and Staphylococcus aureus biofilm clearance. PLoS Pathogens, 2020, 16(3), e1008354. doi: 10.1371/journal.ppat.1008354
  244. Xu, Y.; Deng, Z.; Shi, Y.; Chen, X.; Xu, J.; Zhong, S.; Xiao, Y.; Wong, N.-K.; Zhou, Y. Molecular Imaging and In Situ Quantitative Profiling of Fatty Acid Synthase with a Chemical Probe. Analytical Chemistry, 2020, 92(6), 4419–4426. doi: 10.1021/acs.analchem.9b05327
  245. He, X.; Yuan, Z.; Kao, W.; Miller, D.; Li, S.K.; Park, Y.C. Size-Exclusive Nanoporous Biodegradable PLGA Capsules for Drug Delivery Implants and In Vivo Stability in the Posterior Segment. ACS Applied Bio Materials, 2020, 3(3), 1722–1729. doi: 10.1021/acsabm.0c00027
  246. Zahn, T.; Akhras, S.; Spengler, C.; Murra, R.O.; Holzhauser, T.; Hildt, E. A new approach for therapeutic vaccination against chronic HBV infections. Vaccine, 2020, 38(15), 3105–3120. doi: 10.1016/j.vaccine.2020.02.063
  247. Stein, L.M.; Lhamo, R.; Cao, A.; Workinger, J.; Tinsley, I.; Doyle, R.P.; Grill, H.J.; Hermann, G.E.; Rogers, R.C.; Hayes, M.R. Dorsal vagal complex and hypothalamic glia differentially respond to leptin and energy balance dysregulation. Translational Psychiatry, 2020, 10, 90. doi: 10.1038/s41398-020-0767-0
  248. Saez Talens, V.; Arias-Alpizar, G.; Makurat, D.M.M.; Davis, J.; Bussmann, J.; Kros, A.; Kieltyka, R.E. Stab2-Mediated Clearance of Supramolecular Polymer Nanoparticles in Zebrafish Embryos. Biomacromolecules, 2020, 21(3), 1060–1068. doi: 10.1021/acs.biomac.9b01318
  249. Shao, Z.; Flynn, R.A.; Crowe, J.L.; Zhu, Y.; Liang, J.; Jiang, W.; Aryan, F.; Aoude, P.; Bertozzi, C.R.; Estes, V.M.; Lee, B.J.; Bhagat, G.; Zha, S.; Calo, E. DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis. Nature, 2020, 579, 291–296. doi: 10.1038/s41586-020-2041-2
  250. Comeo, E.; Kindon, N.D.; Soave, M.; Stoddart, L.A.; Kilpatrick, L.; Scammells, P.J.; Hill, S.J.; and Kellam, B. Subtype-selective Fluorescent Ligands as Pharmacological Research Tools for the Human Adenosine A2A Receptor. Journal of Medicinal Chemistry, 2020, 63(5), 2656–2672. doi: 10.1021/acs.jmedchem.9b01856
  251. Stinson, B.M.; Moreno, A.T.; Walter, J.C.; Loparo, J.J. A Mechanism to Minimize Errors during Non-homologous End Joining. Molecular Cell, 2020, 77(5), 1080–1091.e8. doi: 10.1016/j.molcel.2019.11.018
  252. Yuan, X.; Liu, L.; Wang, W.; Gao, Y.-R.; Zhang, D.; Jia, T.-T.; Zeng, H.-R.; Pan, G.; Yuan, Y. Development of (G3-C12)-mediated camptothecin polymeric prodrug targeting to Galectin-3 receptor against androgen-independent prostate cancer. International Journal of Pharmaceutics, 2020, 580, 119123. doi: 10.1016/j.ijpharm.2020.119123
  253. Pereira de Sousa, I.; Gourmel, C.; Berkovska, O.; Burger, M.; Leroux, J.-C. A microparticulate based formulation to protect therapeutic enzymes from proteolytic digestion: phenylalanine ammonia lyase as case study. Scientific Reports, 2020, 10, 3651. doi: 10.1038/s41598-020-60463-y
  254. Braunová, A.; Chytil, P.; Laga, R.; Šírová, M.; Machová, D.; Parnica, J.; Janoušková, O.; Etrych, T. Polymer nanomedicines based on micelle-forming amphiphilic or water-soluble polymer-doxorubicin conjugates: Comparative study of in vitro and in vivo properties related to the polymer carrier structure, composition, and hydrodynamic properties. Journal of Controlled Release, 2020, 321, 718–733. doi: 10.1016/j.jconrel.2020.03.002
  255. Sodano, F.; Cavanagh, R.; Pearce, A.K.; Lazzarato, L.; Rolando, B.; Fraix, A.; Abelha, T.F.; Vasey, C.; Alexander, C.; Taresco, V.; Sortino, S. Enhancing Doxorubicin Anticancer Activity with a Novel Polymeric Platform Photoreleasing Nitric Oxide. Biomaterials Science, 2020, 8(5), 1329–1344. doi: 10.1039/c9bm01644a
  256. Viegas, A.; Dollinger, P.; Verma, N.; Kubiak, J.; Viennet, T.; Seidel, C.A.M.; Gohlke, H.; Etzkorn, M.; Kovacic, F.; Jaeger, K.-E. Structural and dynamic insights revealing how lipase binding domain MD1 of Pseudomonas aeruginosa foldase affects lipase activation. Scientific Reports, 2020, 10, 3578. doi: 10.1038/s41598-020-60093-4
  257. Basu, U.; Lee, S.-W.; Deshpande, A.; Shen, J.; Sohn, B.-K.; Cho, H.; Kim, H.; Patel, S.S. The C-terminal tail of the yeast mitochondrial transcription factor Mtf1 coordinates template strand alignment, DNA scrunching and timely transition into elongation. Nucleic Acids Research, 2020, 48(5), 2604–2620. doi: 10.1093/nar/gkaa040
  258. Kosciuk, T.; Price, I.R.; Zhang, X.; Zhu, C.; Johnson, K.N.; Zhang, S.; Halaby, S.L.; Komaniecki, G.P.; Yang, M.; DeHart, C.J.; Thomas, P.M.; Kelleher, N.L.; Fromme, J.C.; Lin, H. NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle. Nature Communications, 2020, 11, 1067. doi: 10.1038/s41467-020-14893-x
  259. Ecke, M.; Prassler, J.; Tanribil, P.; Müller-Taubenberger, A.; Körber, S.; Faix, J.; Gerisch, G. Formins specify membrane patterns generated by propagating actin waves. Molecular Biology of the Cell, 2020, 31(5), 373–385. doi: 10.1091/mbc.E19-08-0460
  260. Zhou, J.; Wang, W.; Zhang, J.; Du, Z.; Yang, H.; Zhang, G. Click chemistry-based imaging to study tissue distribution of curcumin-protein complex in mice. Food & Function, 2020, 11(2), 1684–1691. doi: 10.1039/c9fo02012h
  261. Landgraf, M.; Lahr, C.A.; Kaur, I.; Shafiee, A.; Sanchez-Herrero, A.; Janowicz, P.W.; Ravichandran, A.; Howard, C.B.; Cifuentes-Rius, A.; McGovern, J.A.; Voelcker, N.H.; Hutmacher, D.W. Targeted camptothecin delivery via silicon nanoparticles reduces breast cancer metastasis. Biomaterials, 2020, 240, 119791. doi: 10.1016/j.biomaterials.2020.119791
  262. Baranova, N.; Radler, P.; Hernández-Rocamora, V.M.; Alfonso, C.; López-Pelegrin, M.; Rivas, G.; Vollmer, W.; Loose, M. Diffusion and capture permits dynamic coupling between treadmilling FtsZ filaments and cell division proteins. Nature Microbiology, 2020, 5, 407–417. doi: 10.1038/s41564-019-0657-5
  263. Akhter, D.T.; Simpson, J.D.; Fletcher, N.L.; Houston, Z.H.; Fuchs, A.V.; Bell, C.A.; Thurecht, K.J. Oral Delivery of Multicompartment Nanomedicines for Colorectal Cancer Therapeutics: Combining Loco-Regional Delivery with Cell-Target Specificity. Advanced Therapeutics, 2020, 3(2), 1900171. doi: 10.1002/adtp.201900171
  264. Choi, J.; Marks, J.; Zhang, J.; Chen, D.-H.; Wang, J.; Vázquez-Laslop, N.; Mankin, A.S:; Puglisi, J.D. Dynamics of the context-specific translation arrest by chloramphenicol and linezolid. Nature Chemical Biology, 2020, 16, 310–317. doi: 10.1038/s41589-019-0423-2
  265. Melms, J.C.; Vallabhaneni, S.; Mills, C.E.; Yapp, C.; Chen, J.-Y.; Morelli, E.; Waszyk, P.; Kumar, S.; Deming, D.; Moret, N.; Rodriguez, S.; Subramanian, K.; Rogava, M.; Cartwright, A.N.R.; Luoma, A.; Mei, S.; Brinker, T.J.; Miller, D.M.; Spektor, A.; Schadendorf, D.; Riggi, N.; Wucherpfennig, K.W.; Sorger, P.K.; Izar, B. Inhibition of Haspin kinase promotes cell-intrinsic and extrinsic anti-tumor activity. Cancer Research, 2020, 80(4), 798–810. doi: 10.1158/0008-5472.CAN-19-2330
  266. Zhang, C.T.; Liu, Y.; Wang, X.; Wang, X.; Kolle, S.; Balazs, A.C.; Aizenberg, J. Patterning non-equilibrium morphologies in stimuli-responsive gels through topographical confinement. Soft Matter, 2020, 16(6), 1463–1472. doi: 10.1039/c9sm02221j
  267. Wang, A.; Kolhe, J.A.; Gioacchini, N.; Baade, I.; Brieher, W.M.; Peterson, C.L.; Freeman, B.C. Mechanism of Long-Range Chromosome Motion Triggered by Gene Activation. Developmental Cell, 2020, 52(3), 309–320.e5. doi: 10.1016/j.devcel.2019.12.007
  268. Solbak, S.M.Ø.; Zang, J.; Narayanan, D.; Høj, Jakobsen, L.; Bucciarelli, S.; Softley, C.; Meier, S.; Langkilde, A.E.; Gotfredsen, C.H.; Sattler, M.; Bach, A. Developing Inhibitors of the p47phox-p22phox Protein-Protein Interaction by Fragment-Based Drug Discovery. Journal of Medicinal Chemistry, 2020, 63(3), 1156–1177. doi: 10.1021/acs.jmedchem.9b01492
  269. de Oliveira, J.K.; Ueda-Nakamura, T.; Corrêa, A.G.; Petrilli, R.; Lopez, R.F.V.; Nakamura, C.V.; Auzely-Velty, R. Liposome-based nanocarrier loaded with a new quinoxaline derivative for the treatment of cutaneous leishmaniasis. Materials Science and Engineering: C, 2020, 110, 110720. doi: 10.1016/j.msec.2020.110720
  270. Garafutdinov, R.R.; Sakhabutdinova, A.R.; Kupryushkin, M.S.; Pyshnyi, D.V. Data on multimerization efficiency for short linear DNA templates and phosphoryl guanidine primers during isothermal amplification with Bst exo- DNA polymerase. Data in Brief, 2020, 29, 105188. doi: 10.1016/j.dib.2020.105188
  271. Sheykhzadeh, S.; Luo, M.; Peng, B.; White, J.; Abdalla, Y.; Tang, T.; Mäkilä, E.; Voelcker, N.H.; Tong, W.Y. Transferrin-targeted porous silicon nanoparticles reduce glioblastoma cell migration across tight extracellular space. Scientific Reports, 2020, 10, 2320. doi: 10.1038/s41598-020-59146-5
  272. Song, P.; Shen, J.; Ye, D.; Dong, B.; Wang, F.; Pei, H.; Wang, J.; Shi, J.; Wang, L.; Xue, W.; Huang, Y.; Huang, G.; Zuo, X.; Fan, C. Programming bulk enzyme heterojunctions for biosensor development with tetrahedral DNA framework. Nature Communications, 2020, 11, 838. doi: 10.1038/s41467-020-14664-8
  273. Romanova, Y.; Laikov, A.; Markelova, M.; Khadiullina, R.; Makseev, A.; Hasanova, M.; Rizvanov, A.; Khaiboullina, S.; Salafutdinov, I. Proteomic Analysis of Human Serum from Patients with Chronic Kidney Disease. Biomolecules, 2020, 10(2), 257. doi: 10.3390/biom10020257
  274. Sundin, C.; Zetterström, C.E.; Vo, D.D.; Brkljača, R.; Urban, S.; Elofsson, M. Exploring resveratrol dimers as virulence blocking agents – Attenuation of type III secretion in Yersinia pseudotuberculosis and Pseudomonas aeruginosa. Scientific Reports, 2020, 10, 2103. doi: 10.1038/s41598-020-58872-0
  275. Tesarova, B.; Dostalova, S.; Smidova, V.; Goliasova, Z.; Skubalova, Z.; Michalkova, H.; Hynek, D.; Michalek, P.; Polanska, H.; Vaculovicova, M.; Hacek, J.; Eckschlager, T.; Stiborova, M.; Pires, A.S.; Neves, A.R.M.; Abrantes, A.M.; Rodrigues, T.; Matafome, P.; Botelho, M.F.; Teixeira, P.; Mendes, F.; Heger, Z. Surface-PASylation of ferritin to form stealth nanovehicles enhances in vivo therapeutic performance of encapsulated ellipticine. Applied Materials Today, 2020, 18, 100501. doi: 10.1016/j.apmt.2019.100501
  276. He, H.; Sofman, M.; Wang, A.J.-S.; Ahrens, C.C.; Wang, W.; Griffith, L.G.; Hammond, P.T. Engineering Helical Modular Polypeptide-Based Hydrogels as Synthetic Extracellular Matrices for Cell Culture. Biomacromolecules, 2020, 21(2), 566–580. doi: 10.1021/acs.biomac.9b01297
  277. Yong, K.; Yuen, D.; Chen, M.Z.; Johnston, A.P.R. Engineering the Orientation, Density and Flexibility of Single Domain Antibodies on Nanoparticles to Improve Cell Targeting. ACS Applied Materials & Interfaces, 2020, 12(5), 5593–5600. doi: 10.1021/acsami.9b20993
  278. Novoselova, M.V.; Loh, H.M.; Trushina, D.B.; Ketkar, A.; Abakumova, T.O.; Zatsepin, T.S.; Kakran, M.; Brzozowska, A.M.; Lau, H.H.; Gorin, D.A.; Antipina, M.N.; Anna, B. Biodegradable Polymeric Multilayer Capsules for Therapy of Lung Cancer. ACS Applied Materials & Interfaces, 2020, 12(5), 5610–5623. doi: 10.1021/acsami.9b21381
  279. Joseph, M.K.; Islam, M.S.; Reineke, J.; Hildreth, M.; Woyengo, T.; Pillatzki, A.; Baride, A.; Perumal, O. Intraductal Drug Delivery to the Breast: Effect of Particle size and Formulation on Breast Duct and Lymph Node Retention. Molecular Pharmaceutics, 2020, 17(2), 441–452. doi: 10.1021/acs.molpharmaceut.9b00879
  280. Song, L.; Chen, Y.; Ding, J.; Wu, H.; Zhang, W.; Ma, M.; Zang, F.; Wang, Z.; Gu, N.; Zhang, Y. Rituximab conjugated iron oxide nanoparticles for targeted imaging and enhanced treatment against CD20-positive lymphoma. Journal of Materials Chemistry B, 2020, 8(5), 895&ndasH,907. doi: 10.1039/C9TB02521A
  281. Adams, M.R.; Moody, C.T.; Sollinger, J.L.; Brudno, Y. Extracellular Matrix-Anchored Click Motifs for Specific Tissue Targeting. Molecular Pharmaceutics, 2020, 17(2), 392–403. doi: 10.1021/acs.molpharmaceut.9b00589
  282. Qiao, H.; Wei, Z.; Wang, Y.; Hu, N.; Sun, S.; Bai, J.; Fang, L.; Wang, Z. Focused characteristics and effects of light reflected from spherical lipid membrane of giant unilamellar vesicles. Colloids and Surfaces, B: Biointerfaces, 2020, 189, 110828. doi: 10.1016/j.colsurfb.2020.110828
  283. Gui, Z.; Zhu, J.; Ye, S.; Ye, J.; Chen, J.; Ling, Y.; Cai, X.; Cao, P.; He, Z.; Hu, C. Prolonged melittin release from polyelectrolyte-based nanocomplexes decreases acute toxicity and improves blood glycemic control in a mouse model of type II diabetes. International Journal of Pharmaceutics, 2020, 577, 119071. doi: 10.1016/j.ijpharm.2020.119071
  284. Yang, Y.; Long, Y.; Wang, Y.; Ren, K.; Li, M.; Zhang, Z.; Xiang, B.; He, Q. Enhanced anti-tumor and anti-metastasis therapy for triple negative breast cancer by CD44 receptor-targeted hybrid self-delivery micelles. International Journal of Pharmaceutics, 2020, 577, 119085. doi: 10.1016/j.ijpharm.2020.119085
  285. Garafutdinov, R.R.; Gilvanov, A.R.; Sakhabutdinova, A.R. The Influence of Reaction Conditions on DNA Multimerization During Isothermal Amplification with Bst exo– DNA Polymerase. Applied Biochemistry and Biotechnology, 2020, 190(2), 758–771. doi: 10.1007/s12010-019-03127-6
  286. Chernikova, E.Y.; Ruleva, A.Y.; Tsvetkov, V.B.; Fedorov, Y.V.; Novikov, V.V.; Aliyeu, T.M.; Pavlov, A.A:; Shepel, N.; Fedorova, O. Cucurbit[7]uril-driven modulation of ligand–DNA interactions by ternary assembly. Organic & Biomolecular Chemistry, 2020, 18(4), 755–766. doi: 10.1039/c9ob02543j
  287. Mahmoud, A.M.; Morrow, J.P.; Pizzi, D.; Nanayakkara, S.; Davis, T.P.; Saito, K.; Kempe, K. Nonionic Water-Soluble and Cytocompatible Poly(amide acrylate)s. Macromolecules, 2020, 53(2), 693–701. doi: 10.1021/acs.macromol.9b02267
  288. Nam, J.; Lim, H.-K.; Kim, N.H.; Park, J.K.; Kang, E.S.; Kim, Y.-T.; Heo, C.; Lee, O.-S.; Kim, S.-G.; Yun, W.S.; Suh, M.; Kim, Y.H. Supramolecular Peptide Hydrogel-Based Soft Neural Interface Augments Brain Signals through Three-Dimensional Electrical Network. ACS Nano, 2020, 14(1), 664–675. doi: 10.1021/acsnano.9b07396
  289. Ast, J.; Arvaniti, A.; Fine, N.H.F.; Nasteska, D.; Ashford, F.B.; Stamataki, Z.; Koszegi, Z.; Bacon, A.; Jones, B.J.; Lucey, M.A.; Sasaki, S.; Brierley, D.I.; Hastoy, B.; Tomas, A.; D'Agostino, G.; Reimann, F.; Lynn, F.C.; Reissaus, C.A.; Linnemann, A.K.; D'Este, E.; Calebiro, D.; Trapp, S.; Johnsson, K.; Podewin, T.; Broichhagen, J.; Hodson, D.J. Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics. Nature Communications, 2020, 11, 467. doi: 10.1038/s41467-020-14309-w
  290. Samaridou, E.; Kalamidas, N.; Santalices, I.; Crecente-Campo, J.; Alonso, M.J. Tuning the PEG surface density of the PEG-PGA enveloped Octaarginine-peptide Nanocomplexes. Drug Delivery and Translational Research, 2020, 10(1), 241–258. doi: 10.1007/s13346-019-00678-3
  291. Antipova, O.M.; Solius, G.M.; Panteleev, D.Y.; Reshetnikov, R.V. Interaction between thrombin and oligonucleotide RA36 is a two-stage process. Biochemical and Biophysical Research Communications, 2020, 522(4), 1037–1040. doi: 10.1016/j.bbrc.2019.11.190
  292. Baksheeva, V.E.; Nemashkalova, E.L.; Firsov, A.M.; Zalevsky, A.O.; Vladimirov, V.I.; Tikhomirova, N.K.; Philippov, P.P.; Zamyatnin, A.A.; Zinchenko, D.V.; Antonenko, Y.N.; Permyakov, S.E.; Zernii, E.Y. Membrane Binding of Neuronal Calcium Sensor-1: Highly Specific Interaction with Phosphatidylinositol-3-Phosphate. Biomolecules, 2020, 10, 164. doi: 10.3390/biom10020164
  293. Nomoto, T.; Inoue, Y.; Yao, Y.; Suzuki, M.; Kanamori, K.; Takemoto, H.; Matsui, M.; Tomoda, K.; Nishiyama, N. Poly(vinyl alcohol) boosting therapeutic potential of p-boronophenylalanine in neutron capture therapy by modulating metabolism. Science Advances, 2020, 6(4), eaaz1722. doi: 10.1126/sciadv.aaz1722
  294. Takemoto, H.; Inaba, T.; Nomoto, T.; Matsui, M.; Liu, X.; Toyoda, M.; Honda, Y.; Taniwaki, K.; Yamada, N.; Kim, J.; Tomoda, K.; Nishiyama, N. Polymeric modification of gemcitabine via cyclic acetal linkage for enhanced anticancer potency with negligible side effects. Biomaterials, 2020, 235, 119804. doi: 10.1016/j.biomaterials.2020.119804
  295. Kim, E.-S.; Kim, D.; Nyberg, S.; Poma, A.; Cecchin, D.; Jain, S.A.; Kim, K.-A.; Shin, Y.-J.; Kim, E.-H.; Kim, M.; Baek, S.-H.; Kim, J.-K.; Doeppner, T.R.; Ali, A.; Redgrave, J.; Battaglia, G.; Majid, A.; Bae, O.-N. LRP-1 functionalized polymersomes enhance the efficacy of carnosine in experimental stroke. Scientific Reports, 2020, 10, 699. doi: 10.1038/s41598-020-57685-5
  296. Korevaar, P.A.; Kaplan, C.N.; Grinthal, A.; Rust, R.M.; Aizenberg, J. Non-equilibrium signal integration in hydrogels. Nature Communications, 2020, 11, 386. doi: 10.1038/s41467-019-14114-0
  297. Pinals, R.L.; Yang, D.; Lui, A.; Cao, W.; Landry, M.P. Corona exchange dynamics on carbon nanotubes by multiplexed fluorescence monitoring. Journal of the American Chemical Society, 2020, 142(3), 1254–1264. doi: 10.1021/jacs.9b09617
  298. Huang, C.-Y.; Yagüe-Capilla, M.; González-Pacanowska, D.; Chang, Z.-F. Quantitation of deoxynucleoside triphosphates by click reactions. Scientific Reports, 2020, 10, 611. doi: 10.1038/s41598-020-57463-3
  299. Naidu, P.S.R.; Denham, E.; Bartlett, C.A.; McGonigle, T.; Taylor, N.L.; Norret, M.; Smith, N.M.; Dunlop, S.A.; Iyer, K.S.; Fitzgerald, M. Protein corona formation moderates the release kinetics of ion channel antagonists from transferrin-functionalized polymeric nanoparticles. RSC Advances, 2020, 10(5), 2856–2869. doi: 10.1039/c9ra09523c
  300. Choi, H.; Hwang, B.W.; Park, K.M.; Kim, K.S.; Hahn, S.K. Degradable Nanomotors Using Platinum Deposited Complex of Calcium Carbonate and Hyaluronate Nanogels for Targeted Drug Delivery. Particle & Particle Systems Characterization, 2020, 37(1), 1900418. doi: 10.1002/ppsc.201900418
  301. Cherkasov, V.R.; Mochalova, E.N.; Babenyshev, A.V.; Rozenberg, J.M.; Sokolov, I.L.; Nikitin, M.P. Antibody-Directed Metal-Organic Framework Nanoparticles for Targeted Drug Delivery. Acta Biomaterialia, 2020, 103, 223–236. doi: 10.1016/j.actbio.2019.12.012
  302. Zhang, P.; Gao, Z.; Cui, J.; Hao, J. Dual-Stimuli-Responsive Polypeptide Nanoparticles for Photothermal and Photodynamic Therapy. ACS Applied Bio Materials, 2020, 3(1), 561–569. doi: 10.1021/acsabm.9b00964
  303. Sameshima, T.; Yukawa, T.; Hirozane, Y.; Yoshikawa, M.; Katoh, T.; Hara, H.; Yogo, T.; Miyahisa, I.; Okuda, T.; Miyamoto, M.; Naven, R. Small-scale panel comprising diverse gene family targets to evaluate compound promiscuity. Chemical Research in Toxicology, 2020, 33(1), 154–161. doi: 10.1021/acs.chemrestox.9b00128
  304. Long, M.J.C; Zhao, Y.; Aye, Y. Clofarabine Commandeers the RNR-α-ZRANB3 Nuclear Signaling Axis. Cell Chemical Biology, 2020, 27(1), 122–133.e5. doi: 10.1016/j.chembiol.2019.11.012
  305. Li, Z.; Pinch, B.J.; Olson, C.M.; Donovan, K.A.; Nowak, R.P.; Mills, C.E.; Scott, D.A.; Doctor, Z.M.; Eleuteri, N.A.; Chung, M.; Sorger, P.K.; Fischer, E.S.; Gray, N.S. Development and Characterization of a Wee1 Kinase Degrader. Cell Chemical Biology, 2020, 27(1), 57–65.e9. doi: 10.1016/j.chembiol.2019.10.013
  306. Imlimthan, S.; Correia, A.; Figueiredo, P.; Lintinen, K.; Balasubramanian, V.; Airaksinen, A.J.; Kostiainen, M.A.; Santos, H.A.; Sarparanta, M. Systematic In Vitro Biocompatibility Studies of Multimodal Cellulose Nanocrystal and Lignin Nanoparticles. Journal of Biomedical Materials Research. Part A, 2020, 108(3), 770–783. doi: 10.1002/jbm.a.36856
  307. Lu, H.; Su, J.; Mamdooh, R.; Li, Y.; Stenzel, M.H. Cellular Uptake of Gold Nanoparticles and Their Movement in 3D Multicellular Tumor Spheroids: Effect of Molecular Weight and Grafting Density of Poly(2-hydroxyl ethyl acrylate). Macromolecular Bioscience, 2020, 20(1), e1900221. doi: 10.1002/mabi.201900221
  308. Baniulis, D.; Sirgėdienė, M.; Haimi, P.; Tamošiūnė, I.; Danusevičius, D. Constitutive and Cold Acclimation-Regulated Protein Expression Profiles of Scots Pine Seedlings Reveal Potential for Adaptive Capacity of Geographically Distant Populations. Forests, 2020, 11(1), 89. doi: 10.3390/f11010089
  309. Steadman, P.E.; Xia, F.; Ahmed, M.; Mocle, A.J.; Penning, A.R.A.; Geraghty, A.C.; Steenland, H.W.; Monje, M.; Josselyn, S.A.; Frankland, P.W. Disruption of Oligodendrogenesis Impairs Memory Consolidation in Adult Mice. Neuron, 2020, 105(1), 150–164.e6. doi: 10.1016/j.neuron.2019.10.013
  310. Holla, S.; Dhakshnamoorthy, J.; Folco, H.D.; Balachandran, V.; Xiao, H.; Sun, L.-L.; Wheeler, D.; Zofall, M.; Grewal, S.I.S. Positioning Heterochromatin at the Nuclear Periphery Suppresses Histone Turnover to Promote Epigenetic Inheritance. Cell, 2020, 180(1), 150–164.e15. doi: 10.1016/j.cell.2019.12.004
  311. Schiapparelli, P.; Zhang, P.; Lara-Velazquez, M.; Guerrero-Cazares, H.; Lin, R.; Su, H.; Chakroun, R.W.; Tusa, M.; Quiñones-Hinojosa, A.; Cui, H. Self-assembling and self-formulating prodrug hydrogelator extends survival in a glioblastoma resection and recurrence model. Journal of Controlled Release, 2020, 319, 311–321. doi: 10.1016/j.jconrel.2020.01.003
  312. Fliervoet, L.A.L.; Lisitsyna, E.S.; Durandin, N.A.; Kotsis, I.; Maas-Bakker, R.F.M.; Yliperttula, M.; Hennink, W.E.; Vuorimaa-Laukkanen, E.; Vermonden, T. Structure and dynamics of thermosensitive pDNA polyplexes studied by time-resolved fluorescence spectroscopy. Biomacromolecules, 2020, 21(1), 73–88. doi: 10.1021/acs.biomac.9b00896
  313. Han, W.; Shi, L.; Xie, B.; Wan, J.; Ren, L.; Wang, Y.; Chen, X.; Wang, H. Supramolecular Engineering of Molecular Inhibitors in an Adaptive Cytotoxic Nanoparticle for Synergistic Cancer Therapy. ACS Applied Materials & Interfaces, 2020, 12(1), 1707–1720. doi: 10.1021/acsami.9b20178
  314. Pola, R.; Böhmová, E.; Filipová, M.; Pechar, M.; Pankrác, J.; Větvička, D.; Olejár, T.; Kabešová, M.; Poučková, P.; Šefc, L.; Zábrodský, M.; Janoušková, O.; Bouček, J.; Etrych, T. Targeted Polymer-Based Probes for Fluorescence Guided Visualization and Potential Surgery of EGFR-Positive Head-and-Neck Tumors. Pharmaceutics, 2020, 12, 31. doi: 10.3390/pharmaceutics12010031
  315. Ni, R.; Song, G.; Fu, X.; Song, R.; Li, L.; Pu, W.; Gao, J.; Hu, J.; Liu, Q.; He, F.; Zhang, D.; Huang, G. Reactive oxygen species-responsive dexamethasone-loaded nanoparticles for targeted treatment of rheumatoid arthritis via suppressing the iRhom2/TNF-α/BAFF signaling pathway. Biomaterials, 2020, 232, 119730. doi: 10.1016/j.biomaterials.2019.119730
  316. Radford, D.C.; Yang, J.; Doan, M.C.; Li, L.; Dixon, A.S.; Owen, S.C.; Kopeček, J. Multivalent HER2-binding polymer conjugates facilitate rapid endocytosis and enhance intracellular drug delivery. Journal of Controlled Release, 2020, 319, 285–299. doi: 10.1016/j.jconrel.2019.12.049
  317. Zhao, Meng and Börner, Richard and Sigel, Roland K. O. and Freisinger, Eva. Site-Specific Dual-Color Labeling of Long RNAs. Methods in Molecular Biology, 2020, 2106, 253–270. doi: 10.1007/978-1-0716-0231-7_16
  318. Taghian, T.; Metelev, V.G.; Zhang, S.; Bogdanov, A.A. Imaging NF-κB activity in a murine model of early stage diabetes. FASEB Journal, 2020, 34(1), 1198–1210. doi: 10.1096/fj.201801147r
  319. Wang, Y.; Dattmore, D.A.; Wang, W:; Pohnert, G.; Wolfram, S.; Zhang, J.; Yang, R.; Decker, E.A.; Lee, K.S.S.; Zhang, G. trans, trans-2,4-decadienal, a lipid peroxidation product, induces inflammatory responses via Hsp90- or 14–3-3ζ-dependent mechanisms. Journal of Nutritional Biochemistry, 2020, 76, 108286. doi: 10.1016/j.jnutbio.2019.108286
  320. Nishimura, T.; Mitsunaga, M.; Ito, K.; Kobayashi, H.; Saruta, M. Cancer neovasculature-targeted near-infrared photoimmunotherapy (NIR-PIT) for gastric cancer: different mechanisms of phototoxicity compared to cell membrane-targeted NIR-PIT. Gastric Cancer, 2020, 23(1), 82–94. doi: 10.1007/s10120-019-00988-y
  321. Kirectepe Aydin, A.; Özgüler, Y.; Uçar, D.; Kasap, M.; Akpınar, G.; Seyahi, E.; Tahir Turanli, E. Peripheral blood mononuclear cell proteome profile in Behçet's syndrome. Rheumatology International, 2020, 40(1), 65–74. doi: 10.1007/s00296-019-04417-2
  322. Kim, H.; Han, J.; Park, J.-H. Cyclodextrin polymer improves atherosclerosis therapy and reduces ototoxicity. Journal of Controlled Release, 2020, 319, 77–86. doi: 10.1016/j.jconrel.2019.12.021
  323. He, Z.; Nie, T.; Hu, Y.; Zhou, Y.; Zhu, J.; Liu, Z.; Liu, L.; Leong, K.W.; Chen, Y.; Mao, H.-Q. A polyphenol-metal nanoparticle platform for tunable release of liraglutide to improve blood glycemic control and reduce cardiovascular complications in a mouse model of type II diabetes. Journal of Controlled Release, 2020, 318, 86–97. doi: 10.1016/j.jconrel.2019.12.014
  324. Zhang, R.; Liu, R.; Liu, C.; Pan, L.; Qi, Y.; Cheng, J.; Guo, J.; Jia, Y.; Ding, J.; Zhang, J.; Hu, H. A pH/ROS dual-responsive and targeting nanotherapy for vascular inflammatory diseases. Biomaterials, 2020, 230, 119605. doi: 10.1016/j.biomaterials.2019.119605
  325. Ereskovsky, A.V.; Tokina, D.B.; Saidov, D.M.; Baghdiguian, S.; Le Goff, E.; Lavrov, A.I. Transdifferentiation and mesenchymal-to-epithelial transition during regeneration in Demospongiae (Porifera). Journal of Experimental Zoology. Part B, 2020, 334(1), 37–58. doi: 10.1002/jez.b.22919
  326. Anani, T.; Brannen, A.; Panizzi, P.; Duin, E.C.; David, A.E. Quantitative, real-time in vivo tracking of magnetic nanoparticles using multispectral optoacoustic tomography (MSOT) imaging. Journal of Pharmaceutical and Biomedical Analysis, 2020, 178, 112951. doi: 10.1016/j.jpba.2019.112951
  327. Ji, W.; Smith, P.N.; Koepsel, R.R.; Andersen, J.D.; Baker, S.L.; Zhang, L.; Carmali, S.; Myerson, J.W.; Muzykantov, V.; Russell, A.J. Erythrocytes as Carriers of Immunoglobulin-Based Therapeutics. Acta Biomaterialia, 2020, 101, 422–435. doi: 10.1016/j.actbio.2019.10.027
  328. Guenter, R.; Aweda, T.; Carmona Matos, D.M.; Jang, S.; Whitt, J.; Cheng, Y.-Q.; Liu, X.M.; Chen, H.; Lapi, S.E.; Jaskula-Sztul, R. Overexpression of somatostatin receptor type 2 in neuroendocrine tumors for improved Ga68-DOTATATE imaging and treatment. Surgery, 2020, 167(1), 189–196. doi: 10.1016/j.surg.2019.05.092
  329. Cliff, L.; Chadda, R.; Robertson, J.L. Occupancy distributions of membrane proteins in heterogeneous liposome populations. BBA Biomembranes, 2020, 1862(1), 183033. doi: 10.1016/j.bbamem.2019.183033
  330. Garafutdinov, R.R.; Sakhabutdinova, A.R.; Kupryushkin, M.S.; Pyshnyi, D.V. Prevention of DNA multimerization using phosphoryl guanidine primers during isothermal amplification with Bst exo- DNA polymerase. Biochimie, 2020, 168, 259–267. doi: 10.1016/j.biochi.2019.11.013
  331. Faidra Angelerou, M.G.; Markus, R.; Paraskevopoulou, V.; Foralosso, R.; Clarke, P.; Alvarez, C.V.; Chenlo, M.; Johnson, L.; Rutland, C.; Allen, S.; Brasnett, C.; Seddon, A.; Zelzer, M.; Marlow, M. Mechanistic investigations into the encapsulation and release of small molecules and proteins from a supramolecular nucleoside gel in vitro and in vivo. Journal of Controlled Release, 2020, 317, 118–129. doi: 10.1016/j.jconrel.2019.10.011
  332. Umakoshi, T.; Fukuda, S.; Iino, R.; Uchihashi, T.; Ando, T. High-speed near-field fluorescence microscopy combined with high-speed atomic force microscopy for biological studies. Biochimica et Biophysica Acta, 2020, 1864(2), 129325. doi: 10.1016/j.bbagen.2019.03.011
  333. Stokol, T.; Wan, C.; Blakely, R.; Bellat, V.; Law, B. Aldoxorubicin-loaded nanofibers are cytotoxic for canine mammary carcinoma and osteosarcoma cell lines in vitro: A short communication. Research in Veterinary Science, 2020, 128, 86–89. doi: 10.1016/j.rvsc.2019.11.003
  334. Sarparanta, M.; Pourat, J.; Carnazza, K.E.; Tang, J.; Paknejad, N.; Reiner, T.; Kostiainen, M.A.; Lewis, J.S. Multimodality labeling strategies for the investigation of nanocrystalline cellulose biodistribution in a mouse model of breast cancer. Nuclear Medicine and Biology, 2020, 80–81, 1–12. doi: 10.1016/j.nucmedbio.2019.11.002
  335. Hyun, H.; Yoo, Y.; Kim, S.Y.; Ko, H.S.; Chun, H.J.; Yang, D.H. Optimization of cRGDfK Ligand Concentration on Polymeric Nanoparticles to Maximize Cancer Targeting. Journal of Industrial and Engineering Chemistry, 2020, 81, 178–184. doi: 10.1016/j.jiec.2019.09.006
  336. Aydemir, M. Triplet-Triplet Annihilation Based Energy Upconversion Mechanism: Cyanine7 Dye Doped with Super Yellow and Rubrene Hosts. Sakarya University Journal of Science, 2020, 24(1), 55–59. doi: 10.16984/saufenbilder.538797

2019

  1. Galstyan, A.; Markman, J. L.; Shatalova, E. S.; Chiechi, A.; Korman, A. J.; Patil, R.; Klymyshyn, D.; Tourtellotte, W. G.; Israel, L. L.; Braubach, O.; Ljubimov, V. A.; Mashouf, L. A.; Ramesh, A.; Grodzinski, Z. B.; Penichet, M. L.; Black, K. L.; Holler, E.; Sun, T.; Ding, H.; Ljubimov, A. V.; Ljubimova, J. Y. Blood–Brain Barrier Permeable Nano Immunoconjugates Induce Local Immune Responses for Glioma Therapy. Nature Communications, 2019, 10(1), 3850. doi: 10.1038/s41467-019-11719-3
  2. Hinman, S. S.; Wang, Y.; Allbritton, N. L. Photopatterned Membranes and Chemical Gradients Enable Scalable Phenotypic Organization of Primary Human Colon Epithelial Models. Anal Chem, 2019, 91(23), 15240–15247. doi: 10.1021/acs.analchem.9b04217
  3. Blanchard, A.T.; Bazrafshan, A.S.; Yi, J.; Eisman, J.T.; Yehl, K.M.; Bian, T.; Mugler, A.; Salaita, K. Highly Polyvalent DNA Motors Generate 100+ pN of Force via Autochemophoresis. Nano Letters, 2019, 19(10), 6977–6986. doi: 10.1021/acs.nanolett.9b02311
  4. Chikate, T.R.; Tang, L. Tracking and Imaging of Transplanted Stem Cells in Animals. Methods in Molecular Biology, 2019, 2150, 45–56. doi: 10.1007/7651_2019_275
  5. Wang, Z.; Cui, M.; Shah, A.M.; Ye, W.; Tan, W.; Min, Y.-L.; Botten, G.A.; Shelton, J.M.; Liu, N.; Bassel-Duby, R.; Olson, E.N. Mechanistic basis of neonatal heart regeneration revealed by transcriptome and histone modification profiling. Proceedings of the National Academy of Sciences of the U.S.A., 2019, 116(37), 18455–18465. doi: 10.1073/pnas.1905824116
  6. Judd, J.; Lovas, J.; Huang, G.N. Defined factors to reactivate cell cycle activity in adult mouse cardiomyocytes. Scientific Reports, 2019, 9, 18830. doi: 10.1038/s41598-019-55027-8
  7. Bayat, N.; McOrist, N.; Ariotti, N.; Lai, M.; Sia, K.C.; Li, Y.; Grace, J.L.; Quinn, J.F.; Whittaker, M.R.; Kavallaris, M.; Davis, T.P.; Lock, R.B. Thiol-Reactive Star Polymers Functionalized with Short Ethoxy-Containing Moieties Exhibit Enhanced Uptake in Acute Lymphoblastic Leukemia Cells. International Journal of Nanomedicine, 2019, 14, 9795–9808. doi: 10.2147/IJN.S220326
  8. Greene, E.R.; Goodall, E.A.; de la Peña, A.H.; Matyskiela, M.E.; Lander, G.C.; Martin, A. Specific lid-base contacts in the 26s proteasome control the conformational switching required for substrate degradation. eLife, 2019, 8, e49806. doi: 10.7554/eLife.49806
  9. Ferrer-González, E.; Fujita, J.; Yoshizawa, T.; Nelson, J.M.; Pilch, A.J.; Hillman, E.; Ozawa, M.; Kuroda, N.; Al-Tameemi, H.M.; Boyd, J.M.; LaVoie, E.J.; Matsumura, H.; Pilch, Daniel S. Structure-Guided Design of a Fluorescent Probe for the Visualization of FtsZ in Clinically Important Gram-Positive and Gram-Negative Bacterial Pathogens. Scientific Reports, 2019, 9, 20092. doi: 10.1038/s41598-019-56557-x
  10. Katsumata, K.; Ishihara, J.; Fukunaga, K.; Ishihara, A.; Yuba, E.; Budina, E.; Hubbell, J.A. Conferring extracellular matrix affinity enhances local therapeutic efficacy of anti-TNF-α antibody in a murine model of rheumatoid arthritis. Arthritis Research & Therapy, 2019, 21, 298. doi: 10.1186/s13075-019-2075-8
  11. Bowen, C.H.; Reed, T.J.; Sargent, C.J.; Mpamo, B.; Galazka, J.M.; Zhang, F. Seeded Chain-Growth Polymerization of Proteins in Living Bacterial Cells. ACS Synthetic Biology, 2019, 8(12), 2651–2658. doi: 10.1021/acssynbio.9b00362
  12. Sharmah, A.; Kraus, M.; Cutler, S.; Siegel, J.B.; Brady, S.; Guo, T. Toward Development of Fluorescence Quenching-Based Biosensors for Drought Stress in Plants. Analytical Chemistry, 2019, 91(24), 15644–15651. doi: 10.1021/acs.analchem.9b03751
  13. Yin, B.; Chan, C.K.W.; Liu, S.; Hong, H.; Wong, S.H.D.; Lee, L.K.C.; Ho, L.W.C.; Zhang, L.; Leung, K.C.-F.; Choi, P.C.-L.; Bian, L.; Tian, X.Y.; Chan, M.N.; Choi, C.H.J. Intrapulmonary Cellular-Level Distribution of Inhaled Nanoparticles with Defined Functional Groups and Its Correlations with Protein Corona and Inflammatory Response. ACS Nano, 2019, 13(12), 14048–14069. doi: 10.1021/acsnano.9b06424
  14. Taskova, M.; Astakhova, K. Fluorescent Oligonucleotides with Bis(prop-2-yn-1-yloxy)butane-1,3-diol Scaffold Rapidly Detect Disease-Associated Nucleic Acids. Bioconjugate Chemistry, 2019, 30(12), 3007–3012. doi: 10.1021/acs.bioconjchem.9b00746
  15. Morais, C.M.; Cunha, P.P.; Melo, T.; Cardoso, A.M.; Domingues, P.; Domingues, M.R.; Pedroso de Lima, M.C.; Jurado, A.S. Glucosylceramide synthase silencing combined with the receptor tyrosine kinase inhibitor axitinib as a new multimodal strategy for glioblastoma. Human Molecular Genetics, 2019, 28(21), 3664–3679. doi: 10.1093/hmg/ddz152
  16. Jeon, M.; Lin, G.; Stephen, Z.R.; Kato, F.L.; Zhang, M. Paclitaxel-Loaded Iron Oxide Nanoparticles for Targeted Breast Cancer Therapy. Advanced Therapeutics, 2019, 2(12), 1900081. doi: 10.1002/adtp.201900081
  17. Beldman, T.J.; Malinova, T.S.; Desclos, E.; Grootemaat, A.E.; Misiak, A.L.S.; van der Velden, S.; van Roomen, C.P.A.A.; Beckers, L.; van Veen, H.A.; Krawczyk, P.M.; Hoebe, R.A.; Sluimer, J.C.; Neele, A.E.; de Winther, M.P.J.; van der Wel, N.N.; Lutgens, E.; Mulder, W.J.M.; Huveneers, S.; Kluza, E. Nanoparticle-Aided Characterization of Arterial Endothelial Architecture during Atherosclerosis Progression and Metabolic Therapy. ACS Nano, 2019, 13(12), 13759–13774. doi: 10.1021/acsnano.8b08875
  18. Hu, H.; Wang, B.; Lai, C.; Xu, X.; Zhen, Z.; Zhou, H.; Xu, D. iRGD-paclitaxel conjugate nanoparticles for targeted paclitaxel delivery. Drug Development Research, 2019, 80(8), 1080–1088. doi: 10.1002/ddr.21589
  19. Chen, F.; Bai, M.; Cao, X.; Zhao, Y.; Xue, J.; Zhao, Y. Click-encoded rolling FISH for visualizing single-cell RNA polyadenylation and structures. Nucleic Acids Research, 2019, 47(22), e145. doi: 10.1093/nar/gkz852
  20. Hofmann, F.J.; Bodnarchuk, M.; Dirin, D.N.; Vogelsang, J.; Kovalenko, M.V.; Lupton, J.M. Energy transfer from perovskite nanocrystals to dye molecules does not occur by FRET. Nano Letters, 2019, 19(12), 8896–8902. doi: 10.1021/acs.nanolett.9b03779
  21. Jiang, Z.; He, H.; Liu, H.; Thayumanavan, S. Cellular Uptake Evaluation of Amphiphilic Polymer Assemblies: Importance of Interplay between Pharmacological and Genetic Approaches. Biomacromolecules, 2019, 20(12), 4407–4418. doi: 10.1021/acs.biomac.9b01073
  22. Martin, C.; Brachet, G.; Colas, C.; Allard-Vannier, E.; Kizlik-Masson, C.; Esnault, C.; Respaud, R.; Denevault-Sabourin, C.; Chourpa, I.; Gouilleux-Gruart, V.; Viaud-Massuard, M.-C.; Joubert, N. In Vitro Characterization and Stability Profiles of Antibody-Fluorophore Conjugates Derived from Interchain Cysteine Cross-Linking or Lysine Bioconjugation. Pharmaceuticals, 2019, 12(4), 176. doi: 10.3390/ph12040176
  23. Dietl, A.; Winkel, I.; Pietrzyk, G.; Paulus, M.; Bruckmann, A.; Schröder, J.A.; Sossalla, S.; Luchner, A.; Maier, L.S.; Birner, C. Skeletal muscle alterations in tachycardia-induced heart failure are linked to deficient natriuretic peptide signalling and are attenuated by RAS-/NEP-inhibition. PloS One, 2019, 14, e0225937. doi: 10.1371/journal.pone.0225937
  24. Duss, O.; Stepanyuk, G.A.; Puglisi, J.D.; Williamson, J.R. Transient Protein-RNA Interactions Guide Nascent Ribosomal RNA Folding. Cell, 2019, 179, 1357–1369.e16. doi: 10.1016/j.cell.2019.10.035
  25. Hu, Y.; Domínguez, C.M.; Bauer, J.; Weigel, S.; Schipperges, A.; Oelschlaeger, C.; Willenbacher, N.; Keppler, S.; Bastmeyer, M.; Heißler, S.; Wöll, C.; Scharnweber, T.; Rabe, K.S.; Niemeyer, C.M. Carbon-nanotube reinforcement of DNA-silica nanocomposites yields programmable and cell-instructive biocoatings. Nature Communications, 2019, 10, 5522. doi: 10.1038/s41467-019-13381-1
  26. Yeung, T.; Fung, O.; Bashkurov, M.; Khandani, A.; Subedar, O.; Wudwud, A.; Shaw, P.; Clarke, B.; Bartlett, J.; Rottapel, R.; Kapus, A. Avoidance of apoptotic death via a hyperploid salvage survival pathway after platinum treatment in high grade serous carcinoma cell line models. Oncotarget, 2019, 10, 6691–6712. doi: 10.18632/oncotarget.27330
  27. Zivanovic, J.; Kouroussis, E.; Kohl, J.B.; Adhikari, B.; Bursac, B.; Schott-Roux, S.; Petrovic, D.; Miljkovic, J.L.; Thomas-Lopez, D.; Jung, Y.; Miler, M.; Mitchell, S.; Milosevic, V.; Gomes, J.E.; Benhar, M.; Gonzales-Zorn, B.; Ivanovic-Burmazovic, I.; Torregrossa, R:; Mitchell, J.R.; Whiteman, M.; Schwarz, G.; Snyder, S.H.; Paul, B.D.; Carroll, K.S.; Filipovic, M.R. Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration. Cell Metabolism, 2019, 30(6), 1152–1170.e13. doi: 10.1016/j.cmet.2019.10.007
  28. Maksimenko, O.; Malinovskaya, Y.; Shipulo, E.; Osipova, N.; Razzhivina, V.; Arantseva, D.; Yarovaya, O.; Mostovaya, U.; Khalansky, A.; Fedoseeva, V.; Alekseeva, A.; Vanchugova, L.; Gorshkova, M.; Kovalenko, E.; Balabanyan, V.; Melnikov, P.; Baklaushev, V.; Chekhonin, V.; Kreuter, J.; Gelperina, S. Doxorubicin-loaded PLGA nanoparticles for the chemotherapy of glioblastomas: Towards the pharmaceutical development. International Journal of Pharmaceutics, 2019, 572, 118733. doi: 10.1016/j.ijpharm.2019.118733
  29. Wu, X.; Zhou, J.; Wang, F.; Meng, X.; Chen, J.; Chang, T.-S.; Lee, M.; Li, G.; Li, X.; Appelman, H.D.; Kuick, R.; Wang, T.D. Detection of colonic neoplasia in vivo using near-infrared-labeled peptide targeting cMet. Scientific Reports, 2019, 9, 17917. doi: 10.1038/s41598-019-54385-7
  30. Dones, J.M.; Tanrikulu, I.C.; Chacko, J.V.; Schroeder, A.B.; Hoang, T.T.; Gibson, A.L.F.; Eliceiri, K.W.; Raines, R.T. Optimization of interstrand interactions enables burn detection with a collagen-mimetic peptide. Organic & Biomolecular Chemistry, 2019, 17(46), 9906–9912. doi: 10.1039/c9ob01839e
  31. Liu, J.; Lee, R.; Britton, B.M.; London, J.A.; Yang, K.; Hanne, J.; Lee, J.-B.; Fishel, R. MutL sliding clamps coordinate exonuclease-independent Escherichia coli mismatch repair. Nature Communications, 2019. doi: 10.1038/s41467-019-13191-5
  32. Kholodenko, I.V.; Kalinovsky, D.V.; Svirshchevskaya, E.V.; Doronin, I.I.; Konovalova, M.V.; Kibardin, A.V.; Shamanskaya, T.V.; Larin, S.S.; Deyev, S.M.; Kholodenko, R.V. Multimerization through Pegylation Improves Pharmacokinetic Properties of scFv Fragments of GD2-Specific Antibodies. Molecules, 2019, 24(21), 3835. doi: 10.3390/molecules24213835
  33. Schwenk, J.; Boudkkazi, S.; Kocylowski, M.K.; Brechet, A.; Zolles, G.; Bus, T.; Costa, K.; Kollewe, A.; Jordan, J.; Bank, J.; Bildl, W.; Sprengel, R.; Kulik, A.; Roeper, J.; Schulte, U.; Fakler, B. An ER Assembly Line of AMPA-Receptors Controls Excitatory Neurotransmission and Its Plasticity. Neuron, 2019, 104(4), 680–692.e9. doi: 10.1016/j.neuron.2019.08.033
  34. Doh, J.; Tobin, S.; Beatty, K. Generation of CoilR Probe Peptides for VIPER-labeling of Cellular Proteins. Bio-protocol, 2019, 9(21), e3412. doi: 10.21769/bioprotoc.3412
  35. Zhou, L.; Wu, Y.; Luo, Y.; Li, H.; Meng, X.; Liu, Cl; Xiang, J.; Zhang, P.; Gong, P.; Cai, L. Mitochondria-localized Self-reporting Small Molecule Decorated Theranostic Agents for Cancer-organelle Transporting and Imaging. ACS Applied Bio Materials, 2019, 2(11), 5164–5173. doi: 10.1021/acsabm.9b00811
  36. Chen, L.; Zeng, D.; Xu, N.; Li, C.; Zhang, W.; Zhu, X.; Gao, Y.; Chen, P.R.; Lin, J. Blood-Brain Barrier- and Blood-Brain Tumor Barrier-Penetrating Peptide-Derived Targeted Therapeutics for Glioma and Malignant Tumor Brain Metastases. ACS Applied Materials & Interfaces, 2019, 11(45), 41889–41897. doi: 10.1021/acsami.9b14046
  37. Nieto-Orellana, A.; Li, H.; Rosiere, R.; Wauthoz, N..; Williams, H.; Monteiro, C.J.; Bosquillon, C.; Childerhouse, N.; Keegan, G.; Coghlan, D.; Mantovani, G.; Stolnik, S. Targeted PEG-poly(glutamic acid) complexes for inhalation protein delivery to the lung. Journal of Controlled Release, 2019, 316, 250–262. doi: 10.1016/j.jconrel.2019.10.012
  38. Saqr, A.; Vakili, M.R.; Huang, Y.-H.; Lai, R.; Lavasanifar, A. Development of Traceable Rituximab-Modified PEO-Polyester Micelles by Postinsertion of PEG-phospholipids for Targeting of B-cell Lymphoma. ACS Omega, 2019, 4(20), 18867–18879. doi: 10.1021/acsomega.9b02910
  39. Zhang, N.; Shi, S.; Jia, T.Z.; Ziegler, A.; Yoo, B.; Yuan, X.; Li, W.; Zhang, S. A general LC-MS-based RNA sequencing method for direct analysis of multiple-base modifications in RNA mixtures. Nucleic Acids Research, 2019, 47(20), e125. doi: 10.1093/nar/gkz731
  40. Katsumata, K.; Ishihara, J.; Mansurov, A.; Ishihara, A.; Raczy, M.M.; Yuba, E.; Hubbell, J.A. Targeting inflammatory sites through collagen affinity enhances the therapeutic efficacy of anti-inflammatory antibodies. Science Advances, 2019, 5(11), eaay1971. doi: 10.1126/sciadv.aay1971
  41. Sayers, E.J.; Peel, S.E.; Schantz, A.; England, R.M.; Beano, M.; Bates, S.M.; Desai, A.S.; Puri, S.; Ashford, M.B.; Jones, A.T. Endocytic Profiling of Cancer Cell Models Reveals Critical Factors Influencing LNP-Mediated mRNA Delivery and Protein Expression. Molecular Therapy, 2019, 27(11), 1950–1962. doi: 10.1016/j.ymthe.2019.07.018
  42. Zheng, Q.; Fang, Y.; Zeng, L.; Li, X.; Chen, H.; Song, H.; Huang, J.; Shi, S. Cytocompatible cerium oxide-mediated antioxidative stress in inhibiting ocular inflammation-associated corneal neovascularization. Journal of Materials Chemistry B, 2019, 7(43), 6759–6769. doi: 10.1039/c9tb01066a
  43. Xu, C.; Yu, Y.; Sun, Y.; Kong, L.; Yang, C.; Hu, M.; Yang, T.; Zhang, J.; Hu, Q.; Zhang, Z. Transformable Nanoparticle-Enabled Synergistic Elicitation and Promotion of Immunogenic Cell Death for Triple-Negative Breast Cancer Immunotherapy. Advanced Functional Materials, 2019, 29(45), 1905213. doi: 10.1002/adfm.201905213
  44. Nozeret, K.; Boucharlat, A.; Agou, F.; Buddelmeijer, N. A sensitive fluorescence-based assay to monitor enzymatic activity of the essential integral membrane protein Apolipoprotein N-acyltransferase (Lnt). Scientific Reports, 2019, 9, 15978. doi: 10.1038/s41598-019-52106-8
  45. Zhong, X.; Shtukenberg, A.G.; Liu, M.; Olson, I.A.; Weck, M.; Ward, M.D.; Kahr, B. Dislocation Generation by Microparticle Inclusions. Crystal Growth & Design, 2019, 19(11), 6649–6655. doi: 10.1021/acs.cgd.9b01041
  46. Phung, C.D.; Nguyen, H.T.; Choi, J.Y.; Pham, T.T.; Acharya, S.; Timilshina, M.; Chang, J.-H.; Kim, J.-H.; Jeong, J.H.; Ku, S.K.; Choi, H.-G.; Yong, C.S.; Kim, J.O. Reprogramming the T cell Response to Cancer by Simultaneous, Nanoparticle-mediated PD-L1 Inhibition and Immunogenic Cell Death. Journal of Controlled Release, 2019, 315, 126–138. doi: 10.1016/j.jconrel.2019.10.047
  47. Yang, Z.; Joyner, A.L. YAP1 is involved in replenishment of granule cell precursors following injury to the neonatal cerebellum. Developmental Biology, 2019, 455(2), 458–472. doi: 10.1016/j.ydbio.2019.07.018
  48. Zettlitz, K.A.; Waldmann, C.M.; Tsai, W.-T.K.; Tavaré, R.; Collins, J.; Murphy, J.M.; Wu, A.M. A Dual-Modality Linker Enables Site-Specific Conjugation of Antibody Fragments for 18F-Immuno-PET and Fluorescence Imaging. Journal of Nuclear Medicine, 2019, 60(10), 1467–1473. doi: 10.2967/jnumed.118.223560
  49. Morimoto, K.; Cole, K.S.; Kourelis, J.; Witt, C.H.; Brown, D.; Krahn, D.; Stegmann, M.; Kaschani, F.; Kaiser, M.; Burton, J.; Mohammed, S.; Yamaguchi-Shinozaki, K.; Weerapana, E.; van der Hoorn, R.A.L. Triazine Probes Target Ascorbate Peroxidases in Plants. Plant Physiology, 2019, 180(4), 1848–1859. doi: 10.1104/pp.19.00481
  50. Sarker, B.; Bagchi, A.; Walter, C.; Almeida, J.; Pathak, A. Longer collagen fibers trigger multicellular streaming on soft substrates via enhanced forces and cell-cell cooperation. Journal of Cell Science, 2019, 132(18), jcs226753. doi: 10.1242/jcs.226753
  51. Zhu, J.; Li, Z.; Zhang, C.; Lin, L.; Cao, S.; Che, H.; Shi, X.; Wang, H.; van Hest, J.C.M. Single enzyme loaded nanoparticles for combinational ultrasound-guided focused ultrasound ablation and hypoxia-relieved chemotherapy. Theranostics, 2019, 9(26), 8048–8060. doi: 10.7150/thno.37054
  52. Mazur, C.; Powers, B.; Zasadny, K.; Sullivan, J.M.; Dimant, H.; Kamme, F.; Hesterman, J.; Matson, J.; Oestergaard, M.; Seaman, M.; Holt, R.W.; Qutaish, M.; Polyak, I.; Coelho, R.; Gottumukkala, V.; Gaut, C.M.; Berridge, M.; Albargothy, N.J.; Kelly, L.; Carare, R.O.; Hoppin, J.; Kordasiewicz, H.; Swayze, E.E.; Verma, A. Brain pharmacology of intrathecal antisense oligonucleotides revealed through multimodal imaging. JCI Insight, 2019, 4(20), 129240. doi: 10.1172/jci.insight.129240
  53. Park, J.; Zhang, Y.; Saito, E.; Gurczynski, S.J.; Moore, B.B.; Cummings, B.J.; Anderson, A.J.; Shea, L.D. Intravascular innate immune cells reprogrammed via intravenous nanoparticles to promote functional recovery after spinal cord injury. Proceedings of the National Academy of Sciences of the U.S.A., 2019, 116(30), 14947–14954. doi: 10.1073/pnas.1820276116
  54. Poreba, M.; Groborz, K.; Vizovisek, M.; Maruggi, M.; Turk, D.; Turk, B.; Powis, G.; Drag, M.; Salvesen, G.S. Fluorescent probes towards selective cathepsin B detection and visualization in cancer cells and patient samples. Chemical Science, 2019, 10(36), 8461–8477. doi: 10.1039/c9sc00997c
  55. Simpson, J.D.; Ediriweera, G.R.; Howard, C.B.; Fletcher, N.L.; Bell, C.A.; Thurecht, K.J. Polymer design and component selection contribute to uptake, distribution & trafficking behaviours of polyethylene glycol hyperbranched polymers in live MDA-MB-468 breast cancer cells. Biomaterials Science, 2019, 7(11), 4661–4674. doi: 10.1039/c9bm00957d
  56. Tran, K.T.; Pallesen, J.S.; Solbak, S.M.Ø.; Narayanan, D.; Baig, A.; Zang, J.; Aguayo-Orozco, A.; Carmona, R.M.C.; Garcia, A.D.; Bach, A. A Comparative Assessment Study of Known Small-Molecule Keap1-Nrf2 Protein-Protein Interaction Inhibitors: Chemical Synthesis, Binding Properties, and Cellular Activity. Journal of Medicinal Chemistry, 2019, 62(17), 8028–8052. doi: 10.1021/acs.jmedchem.9b00723
  57. Luo, M.; Lewik, G.; Ratcliffe, J.C.; Choi, C.H.J.; Mäkilä, E.; Tong, W.Y.; Voelcker, N.H. Systematic Evaluation of Transferrin-Modified Porous Silicon Nanoparticles for Targeted Delivery of Doxorubicin to Glioblastoma. ACS Applied Materials & Interfaces, 2019, 11(37), 33637–33649. doi: 10.1021/acsami.9b10787
  58. Wang, J.; Johnson, A.G.; Lapointe, C.P.; Choi, J.; Prabhakar, A.; Chen, D.-H.; Petrov, A.N.; Puglisi, J.D. eIF5B gates the transition from translation initiation to elongation. Nature, 2019, 573, 605–608. doi: 10.1038/s41586-019-1561-0
  59. Synakewicz, M.; Bauer, D.; Rief, M.; Itzhaki, L.S. Bioorthogonal protein-DNA conjugation methods for force spectroscopy. Scientific Reports, 2019, 9, 13820. doi: 10.1038/s41598-019-49843-1
  60. Broadwater, D.; Bates, M.; Jayaram, M.; Young, M.; He, J.; Raithel, A.L.; Hamann, T.W.; Zhang, W.; Borhan, B.; Lunt, R.R.; Lunt, S.Y. Modulating cellular cytotoxicity and phototoxicity of fluorescent organic salts through counterion pairing. Scientific Reports, 2019, 9, 15288. doi: 10.1038/s41598-019-51593-z
  61. Cundiff, M.D.; Hurley, C.M.; Wong, J.D.; Boscia, J.A.; Bashyal, A.; Rosenberg, J:; Reichard, E.L.; Nassif, N.D.; Brodbelt, J.S.; Kraut, D.A. Ubiquitin receptors are required for substrate-mediated activation of the proteasome's unfolding ability. Scientific Reports, 2019, 9, 14506. doi: 10.1038/s41598-019-50857-y
  62. Caza, F.; Granger Joly de Boissel, P.; Villemur, R.; Betoulle, S.; St-Pierre, Y. Liquid biopsies for omics-based analysis in sentinel mussels. PLoS One, 2019, 14(10), e0223525. doi: 10.1371/journal.pone.0223525
  63. Pinder, C.; Matsuo, Y.; Maurer, S.P.; Toda, T. Kinesin-8 and Dis1/TOG collaborate to limit spindle elongation from prophase to anaphase A for proper chromosome segregation in fission yeast. Journal of Cell Science, 2019, 132(18), jcs232306. doi: 10.1242/jcs.232306
  64. Liu, X.; Ghosh, D. Intracellular nanoparticle delivery by oncogenic KRAS-mediated macropinocytosis. International Journal of Nanomedicine, 2019, 14, 6589–6600. doi: 10.2147/IJN.S212861
  65. Chen, X.; Wang, M.; Yang, X.; Wang, Y.; Yu, L.; Sun, J.; Ding, J. Injectable hydrogels for the sustained delivery of a HER2-targeted antibody for preventing local relapse of HER2+ breast cancer after breast-conserving surgery. Theranostics, 2019, 9(21), 6080–6098. doi: 10.7150/thno.36514
  66. Cun, X.; Chen, J.; Li, M.; He, X.; Tang, X.; Guo, R.; Deng, M.; Li, M.; Zhang, Z.; He, Q. Tumor-Associated Fibroblast-Targeted Regulation and Deep Tumor Delivery of Chemotherapeutic Drugs with a Multifunctional Size-Switchable Nanoparticle. ACS Applied Materials & Interfaces, 2019, 11(43), 39545–39559. doi: 10.1021/acsami.9b13957
  67. Wang, R.; Yao, X.; Li, T.; Li, X.; Jin, M.; Ni, Y.; Yuan, W.; Xie, X.; Lu, L.; Li, M. Reversible Thermoresponsive Hydrogel Fabricated from Natural Biopolymer for the Improvement of Critical Limb Ischemia by Controlling Release of Stem Cells. Advanced Healthcare Materials, 2019, 8(20), 1900967. doi: 10.1002/adhm.201900967
  68. Yen, T.-Y.; Stephen, Z.R.; Lin, G.; Mu, Q.; Jeon, M.; Untoro, S.; Welsh, P.; Zhang, M. Catalase-Functionalized Iron Oxide Nanoparticles Reverse Hypoxia-Induced Chemotherapeutic Resistance. Advanced Healthcare Materials, 2019, 8(20), 1900826. doi: 10.1002/adhm.201900826
  69. Wang, J.; Wang, Z.; Yu, J.; Zhang, Y.; Zeng, Y.; Gu, Z. A forskolin-conjugated insulin analog targeting endogenous glucose-transporter for glucose-responsive insulin delivery. Biomaterials Science, 2019, 7(11), 4508–4513. doi: 10.1039/c9bm01283d
  70. Chin, D.D.; Wang, J.; Mel de Fontenay, M.; Plotkin, A.; Magee, G.A.; Chung, E.J. Hydroxyapatite-binding micelles for the detection of vascular calcification in atherosclerosis. Journal of Materials Chemistry B, 2019, 7(41), 6449–6457. doi: 10.1039/c9tb01918a
  71. Hampoelz, B.; Schwarz, A.; Ronchi, P.; Bragulat-Teixidor, H.; Tischer, C.; Gaspar, I.; Ephrussi, A.; Schwab, Y.; Beck, M. Nuclear Pores Assemble from Nucleoporin Condensates During Oogenesis. Cell, 2019, 179, 671–686.e17. doi: 10.1016/j.cell.2019.09.022
  72. Rho, J.Y.; Cox, H.; Mansfield, E.D.H.; Ellacott, S.H.; Peltier, R.; Brendel, J.C.; Hartlieb, M.; Waigh, T.A.; Perrier, S. Dual self-assembly of supramolecular peptide nanotubes to provide stabilisation in water. Nature Communications, 2019, 10, 4708. doi: 10.1038/s41467-019-12586-8
  73. Li, L.; Wang, J.; Li, Y.; Radford, D.C.; Yang, J.; Kopeček, J. Broadening and Enhancing Functions of Antibodies by Self-Assembling Multimerization at Cell Surface. ACS Nano, 2019, 13(10), 11422–11432. doi: 10.1021/acsnano.9b04868
  74. Che, L.; Liu, Z.; Wang, D.; Xu, C.; Zhang, C.; Meng, J.; Zheng, J.; Yuan, H.; Zhao, G.; Zhou, X. Computer-assisted Engineering of Programmed Drug Releasing Multilayer Nanomedicine via Indomethacin-mediated Ternary Complex for Therapy Against a Multidrug Resistant Tumor. Acta Biomaterialia, 2019, 97, 461–473. doi: 10.1016/j.actbio.2019.07.033
  75. Khatri, S.; Hansen, J.; Mendes, A.C.; Chronakis, I.S.; Hung, S.-C.; Mellins, E.D.; Astakhova, K. Citrullinated Peptide Epitope Targets Therapeutic Nanoparticles to Human Neutrophils. Bioconjugate Chemistry, 2019, 30(10), 2584–2593. doi: 10.1021/acs.bioconjchem.9b00518
  76. Zhu, X.; Nguyen, B.; You, J.B.; Karakolis, E.; Sinton, D.; Rochman, C. Identification of Microfibers in the Environment Using Multiple Lines of Evidence. Environmental Science and Technology, 2019, 53(20), 11877–11887. doi: 10.1021/acs.est.9b05262
  77. Akl, M.A.; Kartal-Hodzic, A.; Suutari, T.; Oksanen, T.; Montagner, I.M.; Rosato, A.; Ismael, H.R.; Afouna, M.I.; Caliceti, P.; Yliperttula, M.; Samy, A.M.; Mastrotto, F.; Salmaso, S.; Viitala, T. Real-Time Label-Free Targeting Assessment and in Vitro Characterization of Curcumin-Loaded Poly-lactic-co-glycolic Acid Nanoparticles for Oral Colon Targeting. ACS Omega, 2019, 4(16), 16878–16890. doi: 10.1021/acsomega.9b02086
  78. Zhou, X.; Ling, K.; Liu, M.; Zhang, X.; Ding, J.; Dong, Y.; Liang, Z.; Li, J.; Zhang, J. Targeted Delivery of Cisplatin-Derived Nanoprecursors via a Biomimetic Yeast Microcapsule for Tumor Therapy by the Oral Route. Theranostics, 2019, 9(22), 6568–6586. doi: 10.7150/thno.35353
  79. Retout, M.; Brunetti, E.; Valkenier, H.; Bruylants, G. Limits of thiol chemistry revealed by quantitative analysis of mixed layers of thiolated-PEG ligands grafted onto gold nanoparticles. Journal of Colloid and Interface Science, 2019, 557, 807–815. doi: 10.1016/j.jcis.2019.09.047
  80. Harris, J.M.; Bentley, M.D.; Moreadith, R.W.; Viegas, T.X.; Fang, Z.; Yoon, K.; Weimer, R.; Dizman, B.; Nordstierna, L. Tuning Drug Release From Polyoxazoline-Drug Conjugates. European Polymer Journal, 2019, 120, 109241. doi: 10.1016/j.eurpolymj.2019.109241
  81. Gapizov, S.Sh.; Petrovskaya, L.E.; Shingarova, L.N.; Kryukova, E.A.; Boldyreva, E.F.; Lukashev, E.P.; Yakimov, S.A.; Svirshchevskaya, E.V.; Dolgikh, D.A.; Kirpichnikov, M.P. Fusion with an albumin-binding domain improves pharmacokinetics of an αvβ3-integrin binding fibronectin scaffold protein. Biotechnology and Applied Biochemistry, 2019, 66(4), 617–625. doi: 10.1002/bab.1762
  82. Antonov, S.A.; Novosadova, E.V.; Kobylansky, A.G.; Tarantul, V.Z.; Grivennikov, I.A. A Hybrid Detection Method Based on Peroxidase-mediated Signal Amplification and Click Chemistry for Highly Sensitive Background-free Immunofluorescent Staining. Journal of Histochemistry & Cytochemistry, 2019, 67(10), 771–782. doi: 10.1369/0022155419864113
  83. Kesarwani, V.; Kelly, H.G.; Shankar, M.; Robinson, K.J.; Kent, S.J.; Traven, A.; Corrie, S.R. Characterisation of key bio-nano interactions between organosilica nanoparticles and Candida albicans. ACS Applied Materials & Interfaces, 2019, 11(38), 34676–34687. doi: 10.1021/acsami.9b10853
  84. Wang, Y.; Yuan, Q.; Feng, W.; Pu, W.; Ding, J.; Zhang, H.; Li, X.; Yang, B.; Dai, Q.; Cheng, L.; Wang, J.; Sun, F.; Zhang, D. Targeted delivery of antibiotics to the infected pulmonary tissues using ROS-responsive nanoparticles. Journal of Nanobiotechnology, 2019, 17, 103. doi: 10.1186/s12951-019-0537-4
  85. Bretin, L.; Pinon, A.; Bouramtane, S.; Ouk, C.; Richard, L.; Perrin, M.-L.; Chaunavel, A.; Carrion, C.; Bregier, F.; Sol, V.; Chaleix, V.; Leger, D.Y.; Liagre, B. Photodynamic Therapy Activity of New Porphyrin-Xylan-Coated Silica Nanoparticles in Human Colorectal Cancer. Cancers, 2019, 11(10), 1474. doi: 10.3390/cancers11101474
  86. Zhang, C.; Ling, X.; Guo, Y.; Yuan, C.; Cheng, H.; Ye, X.; Ma, R.; Zhang, Y.; Li, Y.; Chang, X.; Kong, B.; Liu, T.; Cui, H. Evaluation of COC183B2 antibody targeting ovarian cancer by near-infrared fluorescence imaging. Chinese Journal of Cancer Research, 2019, 31, 673–685. doi: 10.21147/j.issn.1000-9604.2019.04.11
  87. Ou, W.; Jiang, L.; Gu, Y.; Soe, Z.C.; Kim, B.K.; Gautam, M.; Poudel, K.; Pham, L.M.; Phung, C.D.; Chang, J.-H.; Kim, J.R.; Ku, S.K.; Yong, C.S.; Kim, J.O. Regulatory T Cells Tailored with pH-Responsive Liposomes Shape an Immuno-Antitumor Milieu against Tumors. ACS Applied Materials & Interfaces, 2019, 11(40), 36333–36346. doi: 10.1021/acsami.9b11371
  88. Gardinier, T.C.; Turker, M.Z.; Hinckley, J.A.; Katt, W.P.; DomNwachukwu, N.; Woodruff, F.; Hersh, J.; Wang, J.; Cerione, R.A.; Wiesner, U.B. Controlling Surface Chemical Heterogeneities of Ultrasmall Fluorescent Core–Shell Silica Nanoparticles as Revealed by High-Performance Liquid Chromatography. The Journal of Physical Chemistry C, 2019, 123(37), 23246–23254. doi: 10.1021/acs.jpcc.9b06905
  89. Lee, S.A.; Biteen, J.S. Spectral Reshaping of Single Dye Molecules Coupled to Single Plasmonic Nanoparticles. Journal of Physical Chemistry Letters, 2019, 10, 5764–5769. doi: 10.1021/acs.jpclett.9b02480
  90. Srinageshwar, B.; Dils, A.; Sturgis, J.; Wedster, A.; Kathirvelu, B.; Baiyasi, S.; Swanson, D.; Sharma, A.; Dunbar, G.L.; Rossignol, J. Surface-Modified G4 PAMAM Dendrimers Cross the Blood-Brain Barrier Following Multiple Tail-Vein Injections in C57BL/6J Mice. ACS Chemical Neuroscience, 2019, 10(9), 4145–4150. doi: 10.1021/acschemneuro.9b00347
  91. Ju, Y.; Guo, H.; Yarber, F.; Edman, M.C.; Peddi, S.; Janga, S.R.; MacKay, J.A.; Hamm-Alvarez, S.F. Molecular Targeting of Immunosuppressants Using a Bi-functional Elastin-Like Polypeptide. Bioconjugate Chemistry, 2019, 30(9), 2358–2372. doi: 10.1021/acs.bioconjchem.9b00462
  92. Alshanski, I.; Blaszkiewicz, J.; Mervinetsky, E.; Rademann, J.; Yitzchaik, S.; Hurevich, M. Sulfation Patterns of Saccharides and Heavy Metal Ions Binding. Chemistry, 2019, 25(52), 12083–12090. doi: 10.1002/chem.201901538
  93. Hwang, D.; Nilchan, N.; Nanna, A.R.; Li, X.; Cameron, M.D.; Roush, W.R.; Park, H.; Rader, C. Site-Selective Antibody Functionalization via Orthogonally Reactive Arginine and Lysine Residues. Cell Chemical Biology, 2019, 26(9), 1229–1239. doi: 10.1016/j.chembiol.2019.05.010
  94. Jang, E.K.; Son, R.G.; Pack, S.P.;. Novel enzymatic single-nucleotide modification of DNA oligomer: prevention of incessant incorporation of nucleotidyl transferase by ribonucleotide-borate complex. Nucleic Acids Research, 2019, 47(17), e102. doi: 10.1093/nar/gkz612
  95. Zhang, T.; Lip, H.; He, C.; Cai, P.; Wang, Z.; Henderson, J.T.; Rauth, A.M.; Wu, X.Y. Multitargeted Nanoparticles Deliver Synergistic Drugs across the Blood-Brain Barrier to Brain Metastases of Triple Negative Breast Cancer Cells and Tumor-Associated Macrophages. Advanced Healthcare Materials, 2019, 8(18), 1900543. doi: 10.1002/adhm.201900543
  96. Chen, T.; He, B.; Tao, J.; He, Y.; Deng, H.; Wang, X.; Zheng, Y. Application of Förster Resonance Energy Transfer (FRET) technique to elucidate intracellular and in vivo biofate of nanomedicines. Advanced Drug Delivery Reviews, 2019, 143, 177–205. doi: 10.1016/j.addr.2019.04.009
  97. Sundah, N.R.; Ho, N.R.Y.; Lim, G.S.; Natalia, A.; Ding, X.; Liu, Y.; Seet, J.E.; Chan, C.W.; Loh, T.P.; Shao, H. Barcoded DNA nanostructures for the multiplexed profiling of subcellular protein distribution. Nature Biomedical Engineering, 2019, 3(9), 684–694. doi: 10.1038/s41551-019-0417-0
  98. Lee, S.H.; Park, O.K.; Kim, J.; Shin, K.; Pack, C.G.; Kim, K.; Ko, G.; Lee, N.; Kwon, S.-H.; Hyeon, T. Deep tumor penetration of drug-loaded nanoparticles by click reaction-assisted immune cell targeting strategy. Journal of the American Chemical Society, 2019, 141(35), 13829–13840. doi: 10.1021/jacs.9b04621
  99. Saito, E.; Kuo, R.; Kramer, K.R.; Gohel, N.; Giles, D.A.; Moore, B.B.; Miller, S.D.; Shea, L.D. Design of biodegradable nanoparticles to modulate phenotypes of antigen presenting cells for antigen-specific treatment of autoimmune disease. Biomaterials, 2019, 222, 119432. doi: 10.1016/j.biomaterials.2019.119432
  100. Binkley, M.M.; Cui, M.; Li, W.; Tan, S.; Berezin, M.Y.; Meacham, J.M. Design, modeling, and experimental validation of an acoustofluidic platform for nanoscale molecular synthesis and detection. Physics of Fluids, 2019, 31, 082007. doi: 10.1063/1.5100149
  101. Jandl, B.; Sedghiniya, S.; Carstens, A.; Astakhova, K. Peptide–Fluorophore Hydrogel as a Signal Boosting Approach in Rapid Detection of Cancer DNA. ACS Omega, 2019, 4(9), 13889–13895. doi: 10.1021/acsomega.9b01586
  102. Ruiz, A.; Bravo, D.; Duarte, A.; Adler, R.S.; Raya, J.G. Accuracy of Ultrasound-Guided versus Landmark-Guided Intra-articular Injection for Rat Knee Joints. Ultrasound in Medicine and Biology, 2019, 45(10), 2787–2796. doi: 10.1016/j.ultrasmedbio.2019.06.403
  103. Mahmoud, A.; de Jongh, P.; Briere, S.; Chen, M.Z.; Nowell, C.J.; Johnston, A.P.R.; Davis, T.P.; Haddleton, D.M.; Kempe, K. Carboxylated Cy5-labeled Comb Polymers Passively Diffuse the Cell Membrane and Target Mitochondria. ACS Applied Materials & Interfaces, 2019, 11(34), 31302–31310. doi: 10.1021/acsami.9b09395
  104. Kim, H.J.; Yen, L.; Wongpalee, S.P.; Kirshner, J.A.; Mehta, N.; Xue, Y.; Johnston, J.B.; Burlingame, A.L.; Kim, J.K.; Loparo, J.J.; Jacobsen, S.E. The Gene-Silencing Protein MORC-1 Topologically Entraps DNA and Forms Multimeric Assemblies to Cause DNA Compaction. Molecular Cell, 2019, 75, 700–710. doi: 10.1016/j.molcel.2019.07.032
  105. Sergeant, K.; Printz, B.; Guerriero, G.; Renaut, J.; Lutts, S.; Hausman, J.-F. The Dynamics of the Cell Wall Proteome of Developing Alfalfa Stems. Biology, 2019, 8(3), 60. doi: 10.3390/biology8030060
  106. Lomakin, Y.A.; Kudryaeva, A.A.; Kostin, N.N.; Terekhov, S.S.; Kaminskaya, A.N.; Zakharova, M.N.; Ivanova, M.V.; Simaniv, T.O.; Gabibov, A.G.; Belogurov, A.A. Differential Diagnostics of Active Progressing Multiple Sclerosis Using a Fluorescent Biomarker with Resonance Energy Transfer. Bulletin of Experimental Biology and Medicine, 2019, 167(3), 329–334. doi: 10.1007/s10517-019-04520-1
  107. Bruniaux, J.; Allard-Vannier, E.; Aubrey, N.; Lakhrif, Z.; Ben Djemaa, S.; Eljack, S.; Marchais, H.; Hervé-Aubert, K.; Chourpa, I.; David, S. Magnetic nanocarriers for the specific delivery of siRNA: contribution of breast cancer cells active targeting for down-regulation efficiency. International Journal of Pharmaceutics, 2019, 569, 118572. doi: 10.1016/j.ijpharm.2019.118572
  108. Zhuang, Y.; Yang, X.; Li, Y.; Chen, Y.; Peng, X.; Yu, L.; Ding, J. Sustained Release Strategy Designed for Lixisenatide Delivery to Synchronously Treat Diabetes and Associated Complications. ACS Applied Materials & Interfaces, 2019, 11(33), 29604–29618. doi: 10.1021/acsami.9b10346
  109. Kretzmann, J.A.; Evans, C.W.; Moses, C.; Sorolla, A.; Kretzmann, A.L.; Wang, E.; Ho, D.; Hackett, M.J.; Dessauvagie, B.F.; Smith, N.M.; Redfern, A.D.; Waryah, C.; Norret, M.; Iyer, K.S.; Blancafort, P. Tumour suppression by targeted intravenous non-viral CRISPRa using dendritic polymers. Chemical Science, 2019, 10(33), 7718–7727. doi: 10.1039/c9sc01432b
  110. Turker, M.Z.; Gardinier, T.C.; Hinckley, J.A.; Contreras, C.B.; Woodruff, F.; Ma, K.; Kohle, F.F.E.; Wiesner, U.B. Inner and Outer Surface Functionalizations of Ultrasmall Fluorescent Silica Nanorings As Shown by High-Performance Liquid Chromatography. Chemistry of Materials, 2019, 31(15), 5519–5528. doi: 10.1021/acs.chemmater.9b01236
  111. Sharma, P.; Mesci, P.; Carromeu, C.; McClatchy, D.R.; Schiapparelli, L.; Yates, J.R.; Muotri, A.R.; Cline, H.T. Exosomes regulate neurogenesis and circuit assembly. Proceedings of the National Academy of Sciences of the U.S.A., 2019, 116(32), 16086–16094. doi: 10.1073/pnas.1902513116
  112. Pearce, H.A.; Qian, H.; Connell, T.U.; Huang, D.; Gottstein, C.; Donnelly, P.S.; Peter, K.; Gregorevic, P.; Hagemeyer, C.E. Site-specific glycation and chemo-enzymatic antibody sortagging for the retargeting of rAAV6 to inflamed endothelium. Molecular Therapy - Methods & Clinical Development, 2019, 14, 261–269. doi: 10.1016/j.omtm.2019.07.003
  113. Gaikwad, H.; Wang, G.; Smith, W.J.; Alexander, K.L.; D'Alessandro, A.; Zhang, W.; Purev, E.; Simberg, D. Clickable Methyltetrazine-Indocarbocyanine Lipids: A Multicolor Tool Kit for Efficient Modifications of Cell Membranes. Bioconjugate Chemistry, 2019, 30(8), 2106–2114. doi: 10.1021/acs.bioconjchem.9b00202
  114. Melo, M.; Nunes, R.; Sarmento, B.; das Neves, J. Colorectal distribution and retention of polymeric nanoparticles following incorporation into a thermosensitive enema. Biomaterials Science, 2019, 7(9), 3801–3811. doi: 10.1039/c9bm00759h
  115. Bykov, Y.; Cohen, N.; Gabrielli, N.; Manenschijn, H.; Welsch, S.; Chlanda, P.; Kukulski, W.; Patil, K.R.R.; Schuldiner, M.; Briggs, J.A.G. High-throughput ultrastructure screening using electron microscopy and fluorescent barcoding. Journal of Cell Biology, 2019, 218(8), 2797–2811. doi: 10.1083/jcb.201812081
  116. Malfanti, A.; Scomparin, A.; Pozzi, S.; Gibori, H.; Krivitsky, A.; Satchi-Fainaro, R.; Mastrotto, F.; Caliceti, P.; Salmaso, S. Oligo-guanidyl targeted bioconjugates forming rod shaped polyplexes as a new nanoplatform for oligonucleotide delivery. Journal of Controlled Release, 2019, 310, 58–73. doi: 10.1016/j.jconrel.2019.08.005
  117. Kim, K.-S.; Han, J.-H.; Park, J.-H.; Kim, H.-K.; Choi, S.H.; Kim, G.R.; Song, H.; An, H.J.; Han, D.K.; Park, W.; Park, K.-S. Multifunctional nanoparticles for genetic engineering and bioimaging of natural killer (NK) cell therapeutics. Biomaterials, 2019, 221, 119418. doi: 10.1016/j.biomaterials.2019.119418
  118. Rancan, F.; Volkmann, H.; Giulbudagian, M.; Schumacher, F.; Stanko, J.I.; Kleuser, B.; Blume-Peytavi, U.; Calderón, M.; Vogt, A. Dermal Delivery of the High-Molecular-Weight Drug Tacrolimus by Means of Polyglycerol-Based Nanogels. Pharmaceutics, 2019, 11(8), E394. doi: 10.3390/pharmaceutics11080394
  119. Kater, L.; Frieg, B.; Berninghausen, O.; Gohlke, H.; Beckmann, R.; Kedrov, A. Partially inserted nascent chain unzips the lateral gate of the Sec translocon. EMBO Reports, 2019, e48191. doi: 10.15252/embr.201948191
  120. Kosmider, B.; Lin, C.-R.; Karim, L.; Tomar, D.; Vlasenko, L.; Marchetti, N.; Bolla, S.; Madesh, M.; Criner, G.J.; Bahmed, K. Mitochondrial dysfunction in human primary alveolar type II cells in emphysema. EBioMedicine, 2019, 46, 305–316. doi: 10.1016/j.ebiom.2019.07.063
  121. Graber-Feesl, C.L.; Pederson, K.D.; Aney, K.J.; Shima, N. Mitotic DNA Synthesis Is Differentially Regulated between Cancer and Noncancerous Cells. Molecular Cancer Research, 2019, 17(8), 1687–1698. doi: 10.1158/1541-7786.MCR-19-0057
  122. Skubalova, Z.; Michalkova, H.; Michalek, P.; Strmiska, V.; Guran, R.; Rodrigo, M.A.M.; Castkova, K.; Hynek, D.; Pekarik, V.; Zitka, O.; Adam, V.; Heger, Z. Prevalent Anatase Crystalline Phase Increases the Cytotoxicity of Biphasic Titanium Dioxide Nanoparticles in Mammalian Cells. Colloids and Surfaces, B: Biointerfaces, 2019, 182, 110391. doi: 10.1016/j.colsurfb.2019.110391
  123. Brady, S.; Singh, G.; Bolinger, C.; Song, Z.; Boeras, I.; Weng, K.; Trent, B.; Brown, W.C.; Singh, K.; Boris-Lawrie, K.; Heng, X. Virion-associated, host-derived DHX9/RNA helicase A enhances the processivity of HIV-1 reverse transcriptase on genomic RNA. Journal of Biological Chemistry, 2019, 294(30), 11473–11485. doi: 10.1074/jbc.RA119.007679
  124. São Pedro, M.N.; Azevedo, A.M.; Aires-Barros, M.R.; Soares, R.R.G. Minimizing the influence of fluorescent tags on IgG partition in PEG-salt aqueous two-phase systems for rapid screening applications. Biotechnology Journal, 2019, 14(8), 1800640. doi: 10.1002/biot.201800640
  125. Yim, M.S.; Son, E.J.; Kim, H.N.; Ryu, E.K. A TAT-conjugated peptide inhibitor of polo-like kinase 1 for in vivo tumor imaging. Journal of Analytical Science and Technology, 2019, 10(1), 26. doi: 10.1186/s40543-019-0187-z
  126. Yang, F.; Teoh, F.; Tan, A.S.M.; Cao, Y.; Pavelka, N.; Berman, J. Aneuploidy enables cross-adaptation to unrelated drugs. Molecular Biology and Evolution, 2019, 36(8), 1768–1782. doi: 10.1093/molbev/msz104
  127. Jensen, D.; Manzano, A.R.; Rammohan, J.; Stallings, C.L.; Galburt, E.A. CarD and RbpA modify the kinetics of initial transcription and slow promoter escape of the Mycobacterium tuberculosis RNA polymerase. Nucleic Acids Research, 2019, 47(13), 6685–6698. doi: 10.1093/nar/gkz449
  128. Li, Z.; Lin, J.; Sulchek, T.; Cruz, M.A.; Wu, J.; Dong, J.-F.; Zhu, C. Domain specific mechanical modulation of VWF-ADAMTS13 interaction. Molecular Biology of the Cell, 2019, 30(16), 1920–1929. doi: 10.1091/mbc.E19-01-0021
  129. Gao, F.; Hunter, A.; Qu, S.; Hoffman, J.R.; Gao, P.; Phillip, W.A. Interfacial Junctions Control Electrolyte Transport Through Charge-Patterned Membranes. ACS Nano, 2019, 13(7), 7655–7664. doi: 10.1021/acsnano.9b00780
  130. Chen, Y.; Zhao, G.; Wang, S.; He, Y.; Han, S.; Du, C.; Li, S.; Fan, Z.; Wang, C.; Wang, J. Platelet-membrane-camouflaged bismuth sulfide nanorods for synergistic radio-photothermal therapy against cancer. Biomaterials Science, 2019, 7(8), 3450–3459. doi: 10.1039/c9bm00599d
  131. Huang, H.; Zhou, M.; Ruan, L.; Wang, D.; Lu, H.; Zhang, J.; Chen, J.; Hu, Y.; Chai, Z. AMPK mediates the neurotoxicity of iron oxide nanoparticles retained in mitochondria or lysosomes. Metallomics, 2019, 11(7), 1200–1206. doi: 10.1039/c9mt00103d
  132. Chen, C.; Corry, B.; Huang, L.; Hildebrandt, N. FRET-modulated multi-hybrid nanoparticles for brightness-equalized single-wavelength barcoding. Journal of the American Chemical Society, 2019, 141(28), 11123–11141. doi: 10.1021/jacs.9b03383
  133. Nguyen, H.T.; Byeon, J.H.; Phung, C.D.; Pham, L.M.; Ku, S.K.; Yong, C.S.; Kim, J.O. Method for the Instant In-Flight Manufacture of Black Phosphorus to Assemble Core@Shell Nanocomposites for Targeted Photoimmunotherapy. ACS Applied Materials & Interfaces, 2019, 11(28), 24959–24970. doi: 10.1021/acsami.9b04632
  134. Roloff, A.; Nirmalananthan-Budau, N.; Rühle, B.; Borcherding, H.; Thiele, T.; Schedler, U.; Resch-Genger, U. Quantification of Aldehydes on Polymeric Microbead Surfaces via Catch and Release of Reporter Chromophores. Analytical Chemistry, 2019, 91(14), 8827–8834. doi: 10.1021/acs.analchem.8b05515
  135. Al-Lawati, H.; Vakili, M.R.; Lavasanifar, A.; Ahmed, S.; Jamali, F. Delivery and biodistribution of traceable polymeric micellar diclofenac in the rat. Journal of Pharmaceutical Sciences, 2019, 108(8), 2698–2707. doi: 10.1016/j.xphs.2019.03.016
  136. Huang, S.; Qi, J.; deQuilettes, D.W.; Huang, M.; Lin, C.-W.; Bardhan, N.M.; Dang, X.; Bulović, V.; Belcher, A.M. M13 Virus-Based Framework for High Fluorescence Enhancement. Small, 2019, 15(28), 1901233. doi: 10.1002/smll.201901233
  137. Son, K.; You, J.-S.; Yoon, M.-S.; Dai, C.; Kim, J.H.; Khanna, N.; Banerjee, A.; Martinis, S.A.; Han, G.; Han, J.M.; Kim, S.; Chen, J. Nontranslational function of leucyl-tRNA synthetase regulates myogenic differentiation and skeletal muscle regeneration. Journal of Clinical Investigation, 2019, 130, 2088–2093. doi: 10.1172/JCI122560
  138. Zhang, Y.; Pan, J.; Li, H.; Yu, D.; Wu, T.; Wang, L.; Wang, Y.; Zhou, L.; Zheng, S. Albumin Based Nanomedicine for Enhancing Tacrolimus Safety and Lymphatic Targeting Efficiency. Journal of Biomedical Nanotechnology, 2019, 15(6), 1313–1324. doi: 10.1166/jbn.2019.2777
  139. Pantelidou, C.; Sonzogni, O.; De Oliveria Taveira, M.; Mehta, A.K.; Kothari, A.; Wang, D.; Visal, T.; Li, M.K.; Pinto, J.; Castrillon, J.A.; Cheney, E.M.; Bouwman, P.; Jonkers, J.; Rottenberg, S.; Guerriero, J.L.; Wulf, G.M.; Shapiro, G.I. PARP Inhibitor Efficacy Depends on CD8+ T-cell Recruitment via Intratumoral STING Pathway Activation in BRCA-Deficient Models of Triple-Negative Breast Cancer. Cancer Discovery, 2019, 9(6), 722–737. doi: 10.1158/2159-8290.CD-18-1218
  140. Zbyszynski, P.; Toraason, I.; Repp, L.; Kwon, G.S. Probing the subcutaneous absorption of a PEGylated FUD peptide nanomedicine via in vivo fluorescence imaging. Nano Convergence, 2019, 6(1), 22. doi: 10.1186/s40580-019-0192-3
  141. Catipovic, M.A.; Bauer, B.W.; Loparo, J.J.; Rapoport, T.A. Protein translocation by the SecA ATPase occurs by a power-stroke mechanism. EMBO Journal, 2019, 38(9), e101140. doi: 10.15252/embj.2018101140
  142. DuRoss, A.N.; Neufeld, M.J.; Landry, M.R.; Rosch, J.G.; Eaton, C.T.; Sahay, G.; Thomas, C.R.; Sun, C. Micellar Formulation of Talazoparib and Buparlisib for Enhanced DNA Damage in Breast Cancer Chemoradiotherapy. ACS Applied Materials & Interfaces, 2019, 11(13), 12342–12356. doi: 10.1021/acsami.9b02408
  143. Truebenbach, I.; Kern, S.; Loy, D.M.; Höhn, M.; Gorges, J.; Kazmaier, U.; Wagner, E. Combination Chemotherapy of L1210 Tumors in Mice with Pretubulysin and Methotrexate Lipo-Oligomer Nanoparticles. Molecular Pharmaceutics, 2019, 16(6), 2405–2417. doi: 10.1021/acs.molpharmaceut.9b00038
  144. van der Meer, S.B.; Loza, K.; Wey, K.; Heggen, M.; Beuck, C.; Bayer, P.; Epple, M. Click Chemistry on the Surface of Ultrasmall Gold Nanoparticles (2 nm) for Covalent Ligand Attachment Followed by NMR Spectroscopy , 2019, 35(22), 7191–7204. doi: 10.1021/acs.langmuir.9b00295
  145. Parayath, N.N.; Gandham, S.K.; Leslie, F.; Amiji, M.M. Improved Anti-TumorEfficacy of Paclitaxel in Combination with MicroRNA-125b-based Tumor-Associated Macrophage Repolarization in Epithelial Ovarian Cancer. Cancer Letters, 2019, 461, 1–9. doi: 10.1016/j.canlet.2019.07.002
  146. Novoselova, M.V.; Voronin, D.V.; Abakumova, T.O.; Demina, P.A.; Petrov, A.V.; Petrov, V.V.; Zatsepin, T.S.; Sukhorukov, G.B.; Gorin, D.A. Focused ultrasound-mediated fluorescence of composite microcapsules loaded with magnetite nanoparticles: In vitro and in vivo study. Colloids and Surfaces. B: Biointerfaces, 2019, 181, 680–687. doi: 10.1016/j.colsurfb.2019.06.025
  147. Conibear, A.C.; Thewes, K.; Groysbeck, N.; Becker, C.F.W. Multifunctional Scaffolds for Assembling Cancer-Targeting Immune Stimulators Using Chemoselective Ligations. Frontiers in Chemistry, 2019, 7, 113. doi: 10.3389/fchem.2019.00113
  148. Wang, Y.; Li, K.; Han, S.; Tian, Y.-H.; Hu, P.-C.; Xu, X.-L.; He, Y.-Q.; Pan, W.-T.; Gao, Y.; Zhang, Z.; Zhang, J.-W.; Wei, L. Chlorotoxin targets ERα/VASP signaling pathway to combat breast cancer. Cancer Medicine, 2019, 8(4), 1679–1693. doi: 10.1002/cam4.2019
  149. Shi, B.; Wu, M.; Li, Z.; Xie, Z.; Wei, X.; Fan, J.; Xu, Y.; Ding, D.; Akash, S.H.; Chen, S.; Cao, S. Antitumor activity of a 5T4 targeting antibody drug conjugate with a novel payload derived from MMAF via C-Lock linker. Cancer Medicine, 2019, 8(4), 1793–1805. doi: 10.1002/cam4.2066
  150. Yoneoka, S.; Nakagawa, Y.; Uto, K.; Sakura, K.; Tsukahara, T.; Ebara, M. Boron-incorporating hemagglutinating virus of Japan envelope (HVJ-E) nanomaterial in boron neutron capture therapy. Science and Technology of Advanced Materials, 2019, 20(1), 291–304. doi: 10.1080/14686996.2019.1586051
  151. Andersen, V.L.; Vinther, M.; Kumar, R.; Ries, A.; Wengel, J.; Nielsen, J.S.; Kjems, J. A self-assembled, modular nucleic acid-based nanoscaffold for multivalent theranostic medicine. Theranostics, 2019, 9(9), 2662–2677. doi: 10.7150/thno.32060
  152. Kukushkin, V.I.; Ivanov, N.M.; Novoseltseva, A.A.; Gambaryan, A.S.; Yaminsky, I.V.; Kopylov, A.M.; Zavyalova, E.G. Highly sensitive detection of influenza virus with SERS aptasensor. PLoS One, 2019, 14(4), e0216247. doi: 10.1371/journal.pone.0216247
  153. Kirkham, C.M.; Scott, J.N.F.; Wang, X.; Smith, A.L.; Kupinski, A.P.; Ford, A.M.; Westhead, D.R.; Stockley, P.G.; Tuma, R.; Boyes, J. Cut-and-Run: A Distinct Mechanism by which V(D)J Recombination Causes Genome Instability. Molecular Cell, 2019, 74(3), 584–597.e9. doi: 10.1016/j.molcel.2019.02.025
  154. Ha, S.-W.; Hwang, K.; Jin, J.; Cho, A.-S.; Kim, T.Y.; Hwang, S.I.; Lee, H.J.; Kim, C.-Y. Ultrasound-sensitizing nanoparticle complex for overcoming the blood-brain barrier: an effective drug delivery system. International Journal of Nanomedicine, 2019, 14, 3743–3752. doi: 10.2147/ijn.s193258
  155. Zhang, Q.; Zhang, F.; Li, S.; Liu, R.; Jin, T.; Dou, Y.; Zhou, Z.; Zhang, J. A Multifunctional Nanotherapy for Targeted Treatment of Colon Cancer by Simultaneously Regulating Tumor Microenvironment. Theranostics, 2019, 9(13), 3732–3753. doi: 10.7150/thno.34377
  156. Armache, J.P.; Gamarra, N.; Johnson, S.L.; Leonard, J.D.; Wu, S.; Narlikar, G.J.; Cheng, Y. Cryo-EM structures of remodeler-nucleosome intermediates suggest allosteric control through the nucleosome. eLife, 2019, 8, e46057. doi: 10.7554/eLife.46057
  157. Sun, H.; Yan, L.; Chang, M.Y.Z.; Carter, K.; Zhang, R.; Slyker, L.; Lovell, J.; Wu, Y.; Cheng, C. A multifunctional biodegradable brush polymer-drug conjugate for paclitaxel/gemcitabine co-delivery and tumor imaging. Nanoscale Advances, 2019, 1(7), 2761–2771. doi: 10.1039/c9na00282k
  158. Zhang, H.; Zhao, J.; Gu, X.; Wen, Y. Targeted treatment of CD22-positive non-Hodgkin's lymphoma with sialic acid–modified chitosan-PLGA hybrid nanoparticles. Journal of Nanoparticle Research, 2019, 21(7), 154. doi: 10.1007/s11051-019-4595-1
  159. Kravchuk, O.I.; Lyupina, Y.V.; Erokhov, P.A.; Finoshin, A.D.; Adameyko, K.I.; Mishyna, M.Y.; Moiseenko, A.V.; Sokolova, O.S.; Orlova, O.V.; Beljelarskaya, S.N.; Serebryakova, M.V.; Indeykina, M.I.; Bugrova, A.E.; Kononikhin, A.S.; Mikhailov, V.S. Characterization of the 20S proteasome of the lepidopteran, Spodoptera frugiperda. Biochimica et Biophysica Acta - Proteins and Proteomics, 2019, 1867(9), 840–853. doi: 10.1016/j.bbapap.2019.06.010
  160. Vinciguerra, D.; Degrassi, A.; Mancini, L.; Mura, S.; Mougin, J.; Couvreur, P.; Nicolas, J. Drug-Initiated Synthesis of Heterotelechelic Polymer Prodrug Nanoparticles for in Vivo Imaging and Cancer Cell Targeting. Biomacromolecules, 2019, 20(7), 2464–2476. doi: 10.1021/acs.biomac.9b00148
  161. Stankowska, D.L.; Nam, M.-H.; Nahomi, R.B.; Chaphalkar, R.M.; Nandi, S.K.; Fudala, R.; Krishnamoorthy, R.R.; Nagaraj, R.H. Systemically administered peptain-1 inhibits retinal ganglion cell death in animal models: implications for neuroprotection in glaucoma. Cell Death Discovery, 2019, 5(1), 112. doi: 10.1038/s41420-019-0194-2
  162. Ni, C.-W.; Wei, Y.-J.; Shen, Y.-I.; Lee, I.-R. Long-Range Hairpin Slippage Reconfiguration Dynamics in Trinucleotide Repeat Sequences. The Journal of Physical Chemistry Letters, 2019, 10, 3985–3990. doi: 10.1021/acs.jpclett.9b01524
  163. Chariou, P.L.; Dogan, A.B.; Welsh, A.G.; Saidel, G.M.; Baskaran, H.; Steinmetz, N.F. Soil mobility of synthetic and virus-based model nanopesticides. Nature Nanotechnology, 2019, 14(7), 712–718. doi: 10.1038/s41565-019-0453-7
  164. Pola, R.; Parnica, J.; Zuska, K.; Böhmová, E.; Filipová, M.; Pechar, M.; Pankrác, J.; Mucksová, J.; Trefil, P.; Kalina, J.; Šefc, L.; Větvička, D.; Poučková, P.; Bouček, J.; Janoušková, O.; Etrych, T. Oligopeptide-targeted polymer nanoprobes for fluorescence-guided endoscopic surgery. Multifunctional Materials, 2019, 2(2), 024004. doi: 10.1088/2399-7532/ab159e
  165. Liu, R.; Li, Z.; Marvin, J.S.; Kleinfeld, D. Direct wavefront sensing enables functional imaging of infragranular axons and spines. Nature Methods, 2019, 16, 615–618. doi: 10.1038/s41592-019-0434-7
  166. Naidu, P.S.R.; Gavriel, N.; Gray, C.G.G.; Bartlett, C.A.; Toomey, L.M.; Kretzmann, J.; Patalwala, D.; McGonigle, T.; Denham, E.; Hee, C.; Ho, D.; Taylor, N.L.; Norret, M.; Smith, N.M.; Dunlop, S.A.; Iyer, K.S.; Fitzgerald, M. Elucidating the Inability of Functionalized Nanoparticles to Cross the Blood–Brain Barrier and Target Specific Cells In Vivo. ACS Applied Materials & Interfaces, 2019, 11(25), 22085–22095. doi: 10.1021/acsami.9b01356
  167. Rippe, M.; Stefanello, T.F.; Kaplum, V.; Britta, E.A.; Garcia, F.P.; Poirot, R.; Companhoni, M.V.P.; Nakamura, C.V.; Szarpak-Jankowska, A.; Auzély-Velty, R. Heparosan as a potential alternative to hyaluronic acid for the design of biopolymer-based nanovectors for anticancer therapy. Biomaterials Science, 2019, 7, 2850–2860. doi: 10.1039/c9bm00443b
  168. Li, W.; Yalcin, M.; Bharali, D.J.; Lin, Q.; Godugu, K.; Fujioka, K.; Keating, K.A.; Mousa, S.A. Pharmacokinetics, Biodistribution, and Anti-Angiogenesis Efficacy of Diamino Propane Tetraiodothyroacetic Acid-conjugated Biodegradable Polymeric Nanoparticle. Scientific Reports, 2019, 9(1), 9006. doi: 10.1038/s41598-019-44979-6
  169. Comerci, C.J.; Herrmann, J.; Yoon, J.; Jabbarpour, F.; Zhou, X.; Nomellini, J.F.; Smit, J.; Shapiro, L.; Wakatsuki, S.; Moerner, W.E. Topologically-guided continuous protein crystallization controls bacterial surface layer self-assembly. Nature Communications, 2019, 10(1), 2731. doi: 10.1038/s41467-019-10650-x
  170. Narayanaswamy, V.P.; Duncan, A.P.; LiPuma, J.J.; Wiesmann, W.P.; Baker, S.M.; Townsend, S.M. In Vitro Activity of a Novel Glycopolymer against Biofilms of Burkholderia cepacia Complex Cystic Fibrosis Clinical Isolates. Antimicrobial Agents and Chemotherapy, 2019, 63(6), e00498-19. doi: 10.1128/AAC.00498-19
  171. Maisel, S.A.; Broka, D.; Atwell, B.; Bunch, T.; Kupp, R.; Singh, S.K.; Mehta, S.; Schroeder, J. Stapled EGFR peptide reduces inflammatory breast cancer and inhibits additional HER-driven models of cancer. Journal of Translational Medicine, 2019, 17, 201. doi: 10.1186/s12967-019-1939-7
  172. Barnett, D.; Hall, J.; Haab, B. Automated identification and quantification of signals in multichannel immunofluorescence images: the SignalFinder platform. The American Journal of Pathology, 2019, 189(7), 1402–1412. doi: 10.1016/j.ajpath.2019.03.011
  173. Olson, C.M.; Liang, Y.; Leggett, A.; Park, W.D.; Li, L.; Mills, C.E.; Elsarrag, S.Z.; Ficarro, S.B.; Zhang, T.; Düster, R.; Geyer, M.; Sim, T.; Marto, J.A.; Sorger, P.K.; Westover, K.D.; Lin, C.Y.; Kwiatkowski, N.; Gray, N.S. Development of a Selective CDK7 Covalent Inhibitor Reveals Predominant Cell-Cycle Phenotype. Cell Chemical Biology, 2019, 26(6), 792–803.e10. doi: 10.1016/j.chembiol.2019.02.012
  174. Zhu, M.; Lu, D.; Wu, S.; Lian, Q.; Wang, W.; Lyon, A.; Wang, W.; Bartolo, P.; Saunders, B.R. Using green emitting pH-responsive nanogels to report environmental changes within hydrogels: A nanoprobe for versatile sensing. Nanoscale, 2019, 11(24), 11484–11495. doi: 10.1039/c9nr00989b
  175. Li, G.; Lei, Q.; Wang, F.; Deng, D.; Wang, S.; Tian, L.; Shen, W.; Cheng, Y.; Liu, Z. Wu, S. Fluorinated Polymer Mediated Transmucosal Peptide Delivery for Intravesical Instillation Therapy of Bladder Cancer. Small, 2019, 15(25), e1900936. doi: 10.1002/smll.201900936
  176. Gournaris, E.; Park, W.; Cho, S.; Bentrem, D.J.; Larson, A.C.; Kim, D.-H. Near-Infrared Fluorescent Endoscopic Image-guided Photothermal Ablation Therapy of Colorectal Cancer using Dual-modal Gold Nanorods Targeting Tumor Infiltrating Innate Immune Cells in Transgenic TS4 CRE/APCloxΔ468 Mouse Model. ACS Applied Materials & Interfaces, 2019, 11(24), 21353–21359. doi: 10.1021/acsami.9b04186
  177. Shi, L.; Qalieh, A.; Lam, M.M.; Keil, J.M.; Kwan, K.Y. Robust elimination of genome-damaged cells safeguards against brain somatic aneuploidy following Knl1 deletion. Nature Communications, 2019, 10, 2588. doi: 10.1038/s41467-019-10411-w
  178. Nevozhay, D.; Weiger, M.; Friedl, P.; Sokolov, K.V. Spatiotemporally controlled nano-sized third harmonic generation agents. Biomedical Optics Express, 2019, 10(7), 3301. doi: 10.1364/boe.10.003301
  179. Liu, R.; Vairaprakash, P.; Lindsey, J.S. Self-assembly with fluorescence readout in a free base dipyrrin–polymer triggered by metal ion binding in aqueous solution. New Journal of Chemistry, 2019, 43(24), 9711–9724. doi: 10.1039/c9nj01787a
  180. Zhao, C.; Liu, A.; Santamaria, C.M.; Shomorony, A.; Ji, T.; Wei, T.; Gordon, A.; Elofsson, H.; Mehta, M.; Yang, R.; Kohane, D.S. Polymer-tetrodotoxin conjugates to induce prolonged duration local anesthesia with minimal toxicity. Nature Communications, 2019, 10, 2566. doi: 10.1038/s41467-019-10296-9
  181. Hu, H.; Petrosyan, A.; Osna, N.A.; Liu, T.; Olou, A.A.; Alakhova, D.Y.; Singh, P.K.; Kabanov, A.V.; Faber, E.A.; Bronich, T.K. Pluronic block copolymers enhance the anti-myeloma activity of proteasome inhibitors. Journal of Controlled Release, 2019, 306, 149–164. doi: 10.1016/j.jconrel.2019.05.026
  182. Dupré-Crochet, S.; Erard, M.; Nüße, O. Kinetic Analysis of Phagosomal ROS Generation. Methods in Molecular Biology, 2019, 1982, 301–312. doi: 10.1007/978-1-4939-9424-3_18
  183. Kang, M.-S.; Ryu, E.; Lee, S.-W.; Park, J.; Ha, N.Y.; Ra, J.S.; Kim, Y.J.; Kim, J.; Abdel-Rahman, M.; Park, S.H.; Lee, K.-Y.; Kim, H.; Kang, S.; Myung, K. Regulation of PCNA cycling on replicating DNA by RFC and RFC-like complexes. Nature Communications, 2019, 10, 2420. doi: 10.1038/s41467-019-10376-w
  184. Guenter, R.E.; Aweda, T.; Carmona Matos, D.M.; Whitt, J.; Chang, A.W.; Cheng, E.Y.; Liu, X.M.; Chen, H.; Lapi, S.E.; Jaskula-Sztul, R. Pulmonary Carcinoid Surface Receptor Modulation Using Histone Deacetylase Inhibitors. Cancers, 2019, 11(6), 767. doi: 10.3390/cancers11060767
  185. Huang, C.; Zeng, T.; Li, J.; Tan, L.; Deng, X.; Pan, Y.; Chen, Q.; Li, A.; Hu, J. Folate Receptor-mediated Renal-targeting Nanoplatform for the Specific Delivery of Triptolide to Treat Renal Ischemia/Reperfusion Injury. ACS Biomaterials Science & Engineering, 2019, 5(6), 2877–2886. doi: 10.1021/acsbiomaterials.9b00119
  186. Ding, Y.; Liu, J.; Li, X.; Xu, L.; Li, C.; Ma, L.; Liu, J.; Ma, R.; An, Y.; Huang, F.; Liu, Y.; Shi, L. Rational design of drug delivery systems for potential programmable drug release and improved therapeutic effect. Materials Chemistry Frontiers, 2019, 3(6), 1159–1167. doi: 10.1039/c9qm00178f
  187. Burla, F.; Tauber, J.; Dussi, S.; van der Gucht, J.; Koenderink, G.H. Stress management in composite biopolymer networks. Nature Physics, 2019, 15(6), 549–553. doi: 10.1038/s41567-019-0443-6
  188. Zhang, S.; Spiegelman, N.A.; Lin, H. Global Profiling of Sirtuin Deacylase Substrates Using a Chemical Proteomic Strategy and Validation by Fluorescent Labeling. Methods in Molecular Biology, 2019, 2009, 137–147. doi: 10.1007/978-1-4939-9532-5_11
  189. Qi, T.; Chen, B.; Wang, Z.; Du, H.; Liu, D.; Yin, Q.; Liu, B.; Zhang, Q.; Wang, Y. A pH-Activatable nanoparticle for dual-stage precisely mitochondria-targeted photodynamic anticancer therapy. Biomaterials, 2019, 213, 119219. doi: 10.1016/j.biomaterials.2019.05.030
  190. Islam, M.S.; Reineke, J.; Kaushik, R.S.; Woyengo, T.; Baride, A.; Alqahtani, M.S.; Perumal, O. Bioadhesive Food-Protein Nanoparticles as Pediatric Oral Drug Delivery system. ACS Applied Materials & Interfaces, 2019, 11(20), 18062–18073. doi: 10.1021/acsami.9b00152
  191. Dahanayake, V.; Pornrungroj, C.; Pablico-Lansigan, M.; Hickling, W.J.; Lyons, T.; Lah, D.; Lee, Y.-C.; Parasido, E.; Bertke, J.A.; Albanese, C.; Rodriguez, O.; Van Keuren, E.; Stoll, S.L. Paramagnetic Clusters of Mn3(O2CCH3)6(Bpy)2 in Polyacrylamide Nanobeads as a New Design Approach to T1-T2 Multi-Modal MRI Contrast Agent. ACS Applied Materials & Interfaces, 2019, 11(20), 18153–18164. doi: 10.1021/acsami.9b03216
  192. Carniato, F.; Alberti, D.; Lapadula, A.; Martinelli, J.; Isidoro, C.; Crich, S.G.; Tei, L. Multifunctional Gd-based mesoporous silica nanotheranostic for anticancer drug delivery. Journal of Materials Chemistry B, 2019, 7(19), 3143–3152. doi: 10.1039/c9tb00375d
  193. Doll, F.; Steimbach, R.; Zumbusch, A. Direct Imaging of Protein-Specific Methylation in Mammalian Cells. Chembiochem, 2019, 20(10), 1315–1325. doi: 10.1002/cbic.201800787
  194. Svenskaya, Y.I.; Genina, E.A.; Parakhonskiy, B.V.; Lengert, E.; Talnikova, E.E.; Terentyuk, G.S.; Utz, S.R.; Gorin, D.A.; Tuchin, V.V.; Sukhorukov, G. A simple non-invasive approach towards efficient transdermal drug delivery based on biodegradable particulate system. ACS Applied Materials & Interfaces, 2019, 11(19), 17270–17282. doi: 10.1021/acsami.9b04305
  195. Crawford, B.M.; Strobbia, P.; Wang, H.-N.; Zentella, R.; Boyanov, M.; Odion, R.; Pei, Z.-M.; Sun, T.-P.; Kemner, K.M.; Vo-Dinh, T. In vivo nucleic acid detection and imaging within whole plants using plasmonic nanosensors. Advanced Environmental, Chemical, and Biological Sensing Technologies XV (Proceedings SPIE 11007), 2019, 11007, 1100708. doi: 10.1117/12.2524840
  196. Wang, H.-N.; Register, J.K.; Fales, A.M.; Gandra, N.; Strobbia, P.; Cho, E.H.; Boico, A.; Palmer, G.M.; Klitzman, B.; Vo-Dinh, T. Implantable "smart tattoo" SERS nanosensors for in vivo detection of nucleic acid biotargets in a large animal model. Plasmonics in Biology and Medicine XVI (Proceedings SPIE 10894), 2019, 108941J. doi: 10.1117/12.2514634
  197. Nojoumi, S.; Ma, Y.; Schwagerus, S.; Hackenberger, C.P.R.; Budisa, N. In-Cell Synthesis of Bioorthogonal Alkene Tag S-Allyl-Homocysteine and Its Coupling with Reprogrammed Translation. International Journal of Molecular Sciences, 2019, 20(9), 2299. doi: 10.3390/ijms20092299
  198. De France, K.J.; Badv, M.; Dorogin, J.; Siebers, E.; Panchal, V.; Babi, M.; Moran-Mirabal, J.; Lawlor, M.; Cranston, E.D.; Hoare, T. Tissue Response and Biodistribution of Injectable Cellulose Nanocrystal Composite Hydrogels. ACS Biomaterials Science & Engineering, 2019, 5(5), 2235–2246. doi: 10.1021/acsbiomaterials.9b00522
  199. Mo, Y.; Du, H.; Chen, B.; Liu, D.; Yin, Q.; Yan, Y.; Wang, Z.; Wan, F.; Qi, T.; Wang, Y.; Zhang, Q.; Wang, Y. Quick-Responsive Polymer-Based Thermo-Sensitive Liposomes for Controlled Doxorubicin Release and Chemotherapy. ACS Biomaterials Science & Engineering, 2019, 5(5), 2316–2329. doi: 10.1021/acsbiomaterials.9b00343
  200. Wang, S. Single Molecule RNA FISH smFISH in Whole-Mount Mouse Embryonic Organs. Current Protocols in Cell Biology, 2019, 83(1), e79. doi: 10.1002/cpcb.79
  201. Kasprzyk, R.; Starek, B.J.; Ciechanowicz, S.; Kubacka, D.; Kowalska, J.; Jemielity, J. Fluorescent turn-on probes for the development of binding and hydrolytic activity assays for mRNA cap-recognising proteins. Chemistry, 2019, 25(27), 6728–6740. doi: 10.1002/chem.201900051
  202. Zhang, C.Y.; Lin, W.; Gao, J.; Shi, X.; Davaritouchaee, M.; Nielsen, A.E.; Mancini, R.J.; Wang, Z. pH-Responsive Nanoparticles Targeted to Lungs for Improved Therapy of Acute Lung Inflammation/Injury. ACS Applied Materials & Interfaces, 2019, 11(18), 16380–16390. doi: 10.1021/acsami.9b04051
  203. Cohen, J.; Raviv, S.; Adir, O.; Padmanabhan, K.; Soffer, A.; Luxenburg, C. The Wave complex controls epidermal morphogenesis and proliferation by suppressing Wnt-Sox9 signaling. Journal of Cell Biology, 2019, 218(4), 1390–1406. doi: 10.1083/jcb.201807216
  204. Sauer, F.; Klemm, T.; Kollampally, R.B.; Tessmer, I.; Nair, R.K.; Popov, N.; Kisker, C. Differential Oligomerization of the Deubiquitinases USP25 and USP28 Regulates Their Activities. Molecular Cell, 2019, 74(3), 421–435.e10. doi: 10.1016/j.molcel.2019.02.029
  205. Tischer, D.K.; Weiner, O.D. Light-based tuning of ligand half-life supports kinetic proofreading model of T cell signaling. eLIFE, 2019, 8, e42489. doi: 10.7554/eLife.42498
  206. Chan, P.S.; Xian, J.W.; Li, Q.; Chan, C.W.; Leung, S.S.Y.; To, K.K.W. Biodegradable Thermosensitive PLGA-PEG-PLGA Polymer for Non-irritating and Sustained Ophthalmic Drug Delivery. AAPS Journal, 2019, 21, 59. doi: 10.1208/s12248-019-0326-x
  207. Kashfi-Sadabad, R.; Gonzalez-Fajardo, L.; Hargrove, D.; Ahmadi, B:, Munteanu, D.; Shahbazmohamadi, S.; Jay, M.; Lu, X. Engineering Multifunctional Gold Decorated Dendritic Mesoporous Silica/Tantalum Oxide Nanoparticles for Intraperitoneal Tumor-Specific Delivery. Particle & Particle Systems Characterization, 2019, 36(4), 1900058. doi: 10.1002/ppsc.201900058
  208. Yang, H.; Sukamtoh, E.; Du, Z.; Wang, W.; Ando, M.; Kwakwa, Y.N.; Zhang, J.; Zhang, G. Click chemistry approach to characterize curcumin-protein interactions in vitro and in vivo}. The Journal of Nutritional Biochemistry, 2019, 68, 1–6. doi: 10.1016/j.jnutbio.2019.02.010
  209. Guo, S.; Xiao, X.; Wang, X.; Luo, Q.; Zhu, H.; Zhang, H.; Li, H.; Gong, Q.; Luo, K. Reductive microenvironment responsive gadolinium-based polymers as potential safe MRI contrast agents. Biomaterials Science, 2019, 7(5), 1919–1932. doi: 10.1039/c8bm01103f
  210. Erel-Akbaba, G.; Carvalho, L.A.; Tian, T.; Zinter, M.; Akbaba, H.; Obeid, P.J.; Chiocca, E.A.; Weissleder, R.; Kantarci, A.G.; Tannous, B.A. Radiation-Induced Targeted Nanoparticle-Based Gene Delivery for Brain Tumor Therapy. ACS Nano, 2019, 13(4), 4028–4040. doi: 10.1021/acsnano.8b08177
  211. Mildažienė, Vida and Aleknavičiūtė, V.; Žūkienė, R.; Paužaitė, G.; Naučienė, Z.; Filatova, I.; Lyushkevich, V.; Haimi, P.; Tamošiūnė, I.; Baniulis, D. Treatment of Common Sunflower (Helianthus annus L.) Seeds with Radio-frequency Electromagnetic Field and Cold Plasma Induces Changes in Seed Phytohormone Balance, Seedling Development and Leaf Protein Expression. Scientific Reports, 2019, 9, 6437. doi: 10.1038/s41598-019-42893-5
  212. Liu, W.; Zhao, W.; Bai, X.; Jin, S.; Li, Y.; Qiu, C.; Pan, L.; Ding, D.; Xu, Y.; Zhou, Z.; Chen, S. High antitumor activity of Sortase A-generated anti-CD20 antibody fragment drug conjugates. European Journal of Pharmaceutical Sciences, 2019, 134, 81–92. doi: 10.1016/j.ejps.2019.04.015
  213. Tang, G.; Liu, L.; Wang, X.; Pan, Z. Discovery of 7H-pyrrolo[2,3-d]pyrimidine derivatives as selective covalent irreversible inhibitors of interleukin-2-inducible T-cell kinase (Itk). European Journal of Medicinal Chemistry, 2019, 173, 167–183. doi: 10.1016/j.ejmech.2019.03.055
  214. Kholmicheva, N.; Budkina, D.S.; Cassidy, J.; Porotnikov, D.; Harankahage, D.; Boddy, A.; Galindo, M.; Khon, D.; Tarnovsky, A.N.; Zamkov, M. Sustained Biexciton Populations in Nanoshell Quantum Dots. ACS Photonics, 2019, 6(4), 1041–1050. doi: 10.1021/acsphotonics.9b00068
  215. Zemella, A.; Richter, T.; Thoring, L.; Kubick, S. A Combined Cell-Free Protein Synthesis and Fluorescence-Based Approach to Investigate GPCR Binding Properties. Methods in Molecular Biology, 2019, 1947, 57–77. doi: 10.1007/978-1-4939-9121-1_4
  216. Diaz-Salmeron, R.; Ponchel, G.; Bouchemal, K. Hierarchically built hyaluronic nano-platelets have symmetrical hexagonal shape, flattened surfaces and controlled size. European Journal of Pharmaceutical Sciences, 2019, 133, 251–263. doi: 10.1016/j.ejps.2019.04.007
  217. Singh, R.K.; Fan, J.; Gioacchini, N.; Watanabe, S.; Bilsel, O.; Peterson, C.L. Transient Kinetic Analysis of SWR1C-Catalyzed H2A.Z Deposition Unravels the Impact of Nucleosome Dynamics and the Asymmetry of Histone Exchange. Cell Reports, 2019, 27, 374–386.e4. doi: 10.1016/j.celrep.2019.03.035
  218. Phillips, H.R.; Tolstyka, Z.P.; Hall, B.C.; Hexum, J.K.; Hackett, P.B.; Reineke, T.M. Glycopolycation-DNA Polyplex Formulation N/P Ratio Affects Stability, Hemocompatibility, and in Vivo Biodistribution. Biomacromolecules, 2019, 20(4), 1530–1544. doi: 10.1021/acs.biomac.8b01704
  219. Lo, C.-W.; Kryvalap, Y.; Sheu, T.-J.; Chang, C.-H.; Czyzyk, J. Cellular proliferation in mouse and human pancreatic islets is regulated by serpin B13 inhibition and downstream targeting of E-cadherin by cathepsin L. Diabetologia, 2019, 62(5), 822–834. doi: 10.1007/s00125-019-4834-0
  220. Spinelli, A.; Girelli, M.; Arosio, D.; Polito, L.; Podini, P.; Martino, G.; Seneci, P.; Muzio, L.; Menegon, A. Intracisternal delivery of PEG-coated gold nanoparticles results in high brain penetrance and long-lasting stability. Journal of Nanobiotechnology, 2019, 17, 49. doi: 10.1186/s12951-019-0481-3
  221. Steinmetz, H.P.; Rudnick-Glick, S.; Natan, M.; Banin, E.; Margel, S. Poly(styryl bisphosphonate) nanoparticles with a narrow size distribution: Synthesis, characterization and antibacterial applications. European Polymer Journal, 2019, 116, 65–73. doi: 10.1016/j.eurpolymj.2019.04.007
  222. Feczkó, T.; Merza, G.; Babos, G.; Varga, B.; Gyetvai, E.; Trif, L.; Kovács, E.; Tuba, R. Preparation of cubic-shaped sorafenib-loaded nanocomposite using well-defined poly(vinyl alcohol alt-propenylene) copolymer. International Journal of Pharmaceutics, 2019, 562, 333–341. doi: 10.1016/j.ijpharm.2019.03.008
  223. Rojas-Sánchez, L.; Sokolova, V.; Riebe, S.; Voskuhl, J.; Epple, M. Covalent Surface Functionalization of Calcium Phosphate Nanoparticles with Fluorescent Dyes by Copper-Catalysed and by Strain-Promoted Azide-Alkyne Click Chemistry. ChemNanoMat, 2019, 5(4), 436–446. doi: 10.1002/cnma.201800509
  224. Cho, H.-J.; Lee, S.; Park, S.-J.; Lee, Y.-D.; Jeong, K.; Park, J.H.; Lee, Y.-S.; Kim, B.; Jeong, H.-S.; Kim, S. Tumor microenvironment-responsive fluorogenic nanoprobe for ratiometric dual-channel imaging of lymph node metastasis. Colloids and Surfaces B, 2019, 179, 9–16. doi: 10.1016/j.colsurfb.2019.03.047
  225. Lin, P.-Y.; Chen, K.-H.; Miao, Y.-B.; Chen, H.-L.; Lin, K.-J.; Chen, C.-T.; Yeh, C.-N.; Chang, Y.; Sung, H.-W. Phase-Changeable Nanoemulsions for Oral Delivery of a Therapeutic Peptide: Toward Targeting the Pancreas for Antidiabetic Treatments Using Lymphatic Transport. Advanced Functional Materials, 2019, 29(13), 1809015. doi: 10.1002/adfm.201809015
  226. Zhang, Y.; Zhu, X.; Chen, X.; Chen, Q.; Zhou, W.; Guo, Q.; Lu, Y.; Li, C.; Zhang, Y.; Liang, D.; Sun, T.; Wei, X.; Jiang, C. Activated Platelets-Targeting Micelles with Controlled Drug Release for Effective Treatment of Primary and Metastatic Triple Negative Breast Cancer. Advanced Functional Materials, 2019, 29(13), 1806620. doi: 10.1002/adfm.201806620
  227. Howard, G.P.; Verma, G.; Ke, X.; Thayer, W.M.; Hamerly, T.; Baxter, V.K.; Lee, J.E.; Dinglasan, R.R.; Mao, H.-Q. Critical size limit of biodegradable nanoparticles for enhanced lymph node trafficking and paracortex penetration. Nano Research, 2019, 12(4), 837–844. doi: 10.1007/s12274-019-2301-3
  228. Wild, A.R.; Sinnen, B.L.; Dittmer, P.J.; Kennedy, M.J.; Sather, W.A.; Dell'Acqua, M.L. Synapse-to-Nucleus Communication through NFAT Is Mediated by L-type Ca2+ Channel Ca2+ Spike Propagation to the Soma. Cell Reports, 2019, 26, 3537–3550.e4. doi: 10.1016/j.celrep.2019.03.005
  229. Simon, Á.; Gulyás, G.; Mészár, Z.; Bhide, M.; Oláh, J.; Bai, P.; Csősz, É.; Jávor, A.; Komlósi, I.; Remenyik, J.; Czeglédi, L. Proteomics alterations in chicken jejunum caused by 24 h fasting. PeerJ, 2019, 7, e6588. doi: 10.7717/peerj.6588
  230. Liang, S.; Guan, Y.; Zhang, Y. Layer-by-Layer Assembly of Microgel Colloidal Crystals via Photoinitiated Alkyne–Azide Click Reaction. ACS Omega, 2019, 4(3), 5650–5660. doi: 10.1021/acsomega.9b00354
  231. Zheng, L.; Zhao, H.; Han, Y.; Qian, H.; Vukovic, L.; Mecinović, J.; Král, P.; Huck, W.T.S. Catalytic transport of molecular cargo using diffusive binding along a polymer track. Nature Chemistry, 2019, 11(4), 359–366. doi: 10.1038/s41557-018-0204-7
  232. Saito, E.; Kuo, R.; Pearson, R.M.; Gohel, N.; Cheung, B.; King, N.J.C.; Miller, S.D.; Shea, L.D. Designing drug-free biodegradable nanoparticles to modulate inflammatory monocytes and neutrophils for ameliorating inflammation. Journal of Controlled Release, 2019, 300, 185–196. doi: 10.1016/j.jconrel.2019.02.025
  233. He, Z.; Hu, Y.; Gui, Z.; Zhou, Y.; Nie, T.; Zhu, J.; Liu, Z.; Chen, K.; Liu, L.; Leong, K.W.; Cao, P.; Chen, Y.; Mao, H.-Q. Sustained release of exendin-4 from tannic acid/Fe (III) nanoparticles prolongs blood glycemic control in a mouse model of type II diabetes. Journal of Controlled Release, 2019, 301, 119–128. doi: 10.1016/j.jconrel.2019.03.014
  234. Laberge, A.; Ayoub, A.; Arif, S.; Larochelle, S.; Garnier, A.; Moulin, V.J. α-2-Macroglobulin induces the shedding of microvesicles from cutaneous wound myofibroblasts. Journal of Cellular Physiology, 2019, 234(7), 11369–11379. doi: 10.1002/jcp.27794
  235. Kam, A.; Loo, S.; Dutta, B.; Sze, S.K.; Tam, J.P. Plant-derived mitochondria-targeting cysteine-rich peptide modulates cellular bioenergetics. Journal of Biological Chemistry, 2019, 294(11), 4000–4011. doi: 10.1074/jbc.RA118.006693
  236. Xiao, C.; Hu, H.; Yang, H.; Li, S.; Zhou, H.; Ruan, J.; Zhu, Y.; Yang, X.; Li, Z. Colloidal hydroxyethyl starch for tumor-targeted platinum delivery. Nanoscale Advances, 2019, 1(3), 1002–1012. doi: 10.1039/c8na00271a
  237. Crawford, T.; Fletcher, N.; Veitch, M.; Gonzalez Cruz, J.L.; Pett, N.; Brereton, I.; Wells, J.W.; Mobli, M.; Tesiram, Y. Bacillus anthracis Protective Antigen Shows High Specificity for a UV Induced Mouse Model of Cutaneous Squamous Cell Carcinoma. Frontiers in Medicine, 2019, 6, 22. doi: 10.3389/fmed.2019.00022
  238. Wilder, L.M.; Fies, W.A.; Rabin, C.; Webb, L.J.; Crooks, R.M. Conjugation of an α-Helical Peptide to the Surface of Gold Nanoparticles. Langmuir, 2019, 35(9), 3363–3371. doi: 10.1021/acs.langmuir.9b00075
  239. Reyes-Ruiz, J.M.; Osuna-Ramos, J.F.; Bautista-Carbajal, P.; Jaworski, E.; Soto-Acosta, R.; Cervantes-Salazar, M.; Angel-Ambrocio, A.H.; Castillo-Munguía, J.P.; Chávez-Munguía, B.; De Nova-Ocampo, M.; Routh, A.; del Ángel, R.M.; Salas-Benito, J.S. Mosquito cells persistently infected with dengue virus produce viral particles with host-dependent replication. Virology, 2019, 531, 1–18. doi: 10.1016/j.virol.2019.02.018
  240. Shen, Y.; Yang, S.; Hu, X.; Zhang, M.; Ma, X.; Wang, Z.; Hou, Y.; Bai, G. Natural product puerarin activates Akt and ameliorates glucose and lipid metabolism dysfunction in hepatic cells. Journal of Functional Foods, 2019, 55, 296–304. doi: 10.1016/j.jff.2019.02.035
  241. Reichart, F.; Maltsev, O.V.; Kapp, T.G.; Räder, A.F.B.; Weinmüller, M.; Marelli, U.K.; Notni, J.; Wurzer, A.; Beck, R.; Wester, H.-J.; Steiger, K.; Di Maro, S.; Di Leva, F.S.; Marinelli, L.; Nieberler, M.; Reuning, U.; Schwaiger, M.; Kessler, H. Selective Targeting of Integrin αvβ8 by a Highly Active Cyclic Peptide. Journal of Medicinal Chemistry, 2019, 62(4), 2024–2037. doi: 10.1021/acs.jmedchem.8b01588
  242. Le, D.H.T.; Commandeur, U.; Steinmetz, N.F. Presentation and Delivery of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand via Elongated Plant Viral Nanoparticle Enhances Antitumor Efficacy. ACS Nano, 2019, 13(2), 2501–2510. doi: 10.1021/acsnano.8b09462
  243. Crawford, B.M.; Strobbia, P.; Wang, H.-N.; Zentella, R.; Boyanov, M.I.; Pei, Z.-M.; Sun, T.-P.; Kemner, K.M.; Vo-Dinh, T. Plasmonic nanoprobes for in vivo multimodal sensing and bioimaging of microRNA within plants. ACS Applied Materials & Interfaces, 2019, 11(8), 7743–7754. doi: 10.1021/acsami.8b19977
  244. Dong, B.; Du, S.; Wang, C.; Fu, H.; Li, Q.; Xiao, N.; Yang, J.; Xue, X.; Cai, W.; Liu, D. Reversible Self-Assembly of Nanoprobes in Live Cells for Dynamic Intracellular pH Imaging. ACS Nano, 2019, 13(2), 1421–1432. doi: 10.1021/acsnano.8b07054
  245. Feltes, M.; Moores, S.; Gale, S.E.; Krishnan, K.; Mydock-McGrane, L.; Covey, D.F.; Ory, D.S.; Schaffer, J.E. Synthesis and characterization of diazirine alkyne probes for the study of intracellular cholesterol trafficking. Journal of Lipid Research, 2019, 60(3), 707–716. doi: 10.1194/jlr.D091470
  246. Guo, A.; Durymanov, M.; Permyakova, A.; Sene, S.; Serre, C.; Reineke, J. Metal Organic Framework (MOF) Particles as Potential Bacteria-Mimicking Delivery Systems for Infectious Diseases: Characterization and Cellular Internalization in Alveolar Macrophages , 2019, 36, 53. doi: 10.1007/s11095-019-2589-4
  247. Yang, C.; Liu, D.; Renny, A.; Kuttipillai, P.S.; Lunt, R.R. Integration of near-infrared harvesting transparent luminescent solar concentrators onto arbitrary surfaces. Journal of Luminescence, 2019, 210, 239–246. doi: 10.1016/j.jlumin.2019.02.042
  248. Guo, J.; Mingoes, C.; Qiu, X.; Hildebrandt, N. Simple, Amplified, and Multiplexed Detection of MicroRNAs Using Time-Gated FRET and Hybridization Chain Reaction. Analytical Chemistry, 2019, 91(4), 3101–3109. doi: 10.1021/acs.analchem.8b05600
  249. Elrod, N.R.; Jaworski, E.A.; Ji, P.; Wagner, E.J.; Routh, A. Development of Poly(A)-ClickSeq as a Tool Enabling Simultaneous Genome-wide Poly(A)-site identification and Differential Expression Analysis. Methods, 2019, 155, 20–29. doi: 10.1016/j.ymeth.2019.01.002
  250. Madl, C.M.; LeSavage, B.L.; Dewi, R.E.; Lampe, K.J.; Heilshorn, S.C. Matrix Remodeling Enhances the Differentiation Capacity of Neural Progenitor Cells in 3D Hydrogels. Advanced Science, 2019, 6(4), 1801716. doi: 10.1002/advs.201801716
  251. De France, K.J.; Babi, M.; Vapaavuori, J.; Hoare, T.; Moran-Mirabal, J.M.; Cranston, E.D. 2.5D Hierarchical Structuring of Nanocomposite Hydrogel Films Containing Cellulose Nanocrystals. ACS Applied Materials & Interfaces, 2019, 11(6), 6325–6335. doi: 10.1021/acsami.8b16232
  252. Liu, X.; Nemeth, D.P.; McKim, D.B.; Zhu, L.; DiSabato, D.J.; Berdysz, O.; Gorantla, G.; Oliver, B.; Witcher, K.G.; Wang, Y.; Negray, C.E.; Vegesna, R.S.; Sheridan, J.F.; Godbout, J.P.; Robson, M.J.; Blakely, R.D.; Popovich, P.G.; Bilbo, S.D.; Quan, N. Cell-Type-Specific Interleukin 1 Receptor 1 Signaling in the Brain Regulates Distinct Neuroimmune Activities. Immunity, 2019, 50(2), 317–333.e6. doi: 10.1016/j.immuni.2018.12.012
  253. Du, T.; Buenbrazo, N.; Kell, L.; Rahmani, S.; Sim, L.; Withers, S.G.; DeFrees, S.; Wakarchuk, W.;. A Bacterial Expression Platform for Production of Therapeutic Proteins Containing Human-like O-Linked Glycans. Cell Chemical Biology, 2019, 26(2), 203–212.e5. doi: 10.1016/j.chembiol.2018.10.017
  254. Gagni, P.; Romanato, A.; Bergamaschi, G.; Bettotti, P.; Vanna, R.; Piotto, C.; Morasso, C.F.; Chiari, M.; Cretich, M.; Gori, A. A self-assembling peptide hydrogel for ultrarapid 3D bioassays. Nanoscale Advances, 2019, 1(2), 490–497. doi: 10.1039/c8na00158h
  255. Lee, M.-R.; Raman, N.; Ortiz-Bermúdez, P.; Lynn, D.M.; Palecek, S.P. 14-Helical β-Peptides Elicit Toxicity against C. albicans by Forming Pores in the Cell Membrane and Subsequently Disrupting Intracellular Organelles. Cell Chemical Biology, 2019, 26(2), 289–299.e4. doi: 10.1016/j.chembiol.2018.11.002
  256. Tesarova, B.; Charousova, M.; Dostalova, S.; Bienko, A.; Kopel, P.; Kruszyński, R.; Hynek, D.; Michalek, P.; Eckschlager, T.; Stiborova, M.; Adam, V.; Heger, Z. Folic acid-mediated re-shuttling of ferritin receptor specificity towards a selective delivery of highly cytotoxic nickel(II) coordination compounds. International Journal of Biological Macromolecules, 2019, 126, 1099–1111. doi: 10.1016/j.ijbiomac.2018.12.128
  257. Zhang, H.; Wu, J.; Wu, J.; Fan, Q.; Zhou, J.; Wu, J.; Liu, S.; Zang, J.; Ye, J.; Xiao, M.; Tian, T.; Gao, J. Exosome-mediated targeted delivery of miR-210 for angiogenic therapy after cerebral ischemia in mice. Journal of Nanobiotechnology, 2019, 17, 29. doi: 10.1186/s12951-019-0461-7
  258. Tobola, F.; Sylvander, E.; Gafko, C.; Wiltschi, B. `Clickable lectins': bioorthogonal reactive handles facilitate the directed conjugation of lectins in a modular fashion. Interface Focus, 2019, 9(2), 20180072. doi: 10.1098/rsfs.2018.0072
  259. Cao, P.; Wei, X.; Awal, R.P.; Müller, R.; Wall, D. A Highly Polymorphic Receptor Governs Many Distinct Self-Recognition Types within the Myxococcales Order. mBio, 2019, 10, e02751-18. doi: 10.1128/mBio.02751-18
  260. Shim, G.; Le, Q.-V.; Suh, J.; Choi, S.; Kim, G.; Choi, H.-G.; Kim, Y.B.; Macgregor, M.B.; Oh, Y.-K. Sequential activation of anticancer therapy triggered by tumor microenvironment-selective imaging. Journal of Controlled Release, 2019, 298, 110–119. doi: 10.1016/j.jconrel.2019.02.012
  261. Vishnu Vardhan, G.P.; Hema, M.; Sushmitha, C.; Savithri, H.S.; Natraj, U.; Murthy, M.R.N. Development of sesbania mosaic virus nanoparticles for imaging. Archives of Virology, 2019, 164(2), 497–507. doi: 10.1007/s00705-018-4097-y
  262. Chen, Y.; Fan, H.; Xu, C.; Hu, W.; Yu, B. Efficient Cholera Toxin B Subunit-Based Nanoparticles with MRI Capability for Drug Delivery to the Brain Following Intranasal Administration. Macromolecular Bioscience, 2019, 19(2), 1800340. doi: 10.1002/mabi.201800340
  263. Gu, W.; Bobrin, V.A.; Chen, S.-P.R.; Wang, Z.; Schoning, J.P.; Gu, Y.; Chen, W.; Chen, M.; Jia, Z.; Monteiro, M.J. Biodistribution of PNIPAM-Coated Nanostructures Synthesized by the TDMT Method. Biomacromolecules, 2019, 20(2), 625–634. doi: 10.1021/acs.biomac.8b01196
  264. Sun, H.; Yan, L.; Carter, K.A.; Zhang, J.; Caserto, J.; Lovell, J.F.; Wu, Y.; Cheng, C. Zwitterionic Crosslinked Biodegradable Nanocapsules for Cancer Imaging. Langmuir, 2019, 35(5), 1440–1449. doi: 10.1021/acs.langmuir.8b01633
  265. Hou, W.; Li, Y.; Kang, W.; Wang, X.; Wu, X.; Wang, S.; Liu, F. Real-time analysis of quantum dot labeled single porcine epidemic diarrhea virus moving along the microtubules using single particle tracking. Scientific Reports, 2019, 9, 1307. doi: 10.1038/s41598-018-37789-9
  266. Wilson, D.R.; Rui, Y.; Siddiq, K.; Routkevitch, D.; Green, J.J. Differentially Branched Ester Amine Quadpolymers with Amphiphilic and pH Sensitive Properties for Efficient Plasmid DNA Delivery. Molecular Pharmaceutics, 2019, 16(2), 655–668. doi: 10.1021/acs.molpharmaceut.8b00963
  267. Kuznetsov, A.E.; Komarova, N.V.; Kuznetsov, E.V.; Andrianova, M.S.; Grudtsov, V.P.; Rybachek, E.N.; Puchnin, K.V.; Ryazantsev, D.V.; Saurov, A.N. Integration of a field effect transistor-based aptasensor under a hydrophobic membrane for bioelectronic nose applications. Biosensors and Bioelectronics, 2019, 129, 29–35. doi: 10.1016/j.bios.2019.01.013
  268. Ni, Y.; Arts, R.; Merkx, M. Ratiometric bioluminescent sensor proteins based on intramolecular split luciferase complementation. ACS Sensors, 2019, 4(1), 20–25. doi: 10.1021/acssensors.8b01381
  269. Hortelao, A.C.; Carrascosa, R.; Murillo-Cremaes, N.; Patiño, T.; Sanchez, S. Targeting 3D Bladder Cancer Spheroids with Urease-Powered Nanomotors. ACS Nano, 2019, 13(1), 429–439. doi: 10.1021/acsnano.8b06610
  270. Liu, Y.; Li, Q.; Xiong, X.; Zhou, Z. Improved mitochondrial targeting effect of HPMA copolymer by SS20 peptide mediation and nonendocytosis pathway. Journal of Peptide Science, 2019, 25(2), e4133. doi: 10.1002/psc.3144
  271. Kwon, Y.-D.; Oh, J.-M.; La, M.T.; Chung, H.-J.; Lee, S.J.; Chun, S.; Lee, S.-H.; Jeong, B.-H.; Kim, H.-K. Synthesis and Evaluation of Multifunctional Fluorescent Inhibitors with Synergistic Interaction of PSMA and Hypoxia for Prostate Cancer. Bioconjugate Chemistry, 2019, 30(1), 90–100. doi: 10.1021/acs.bioconjchem.8b00767
  272. Zhang, X.; Shi, H.; Zhang, R.; Zhang, J.; Xu, F.; Qiao, L.; Yu, S. The Competitive Dynamic Binding of Some Blood Proteins Adsorbed on Gold Nanoparticles. Particle & Particle Systems Characterization, 2019, 36(1), 1800257. doi: 10.1002/ppsc.201800257
  273. Cooper, C.E.; Silkstone, G.G.A.; Simons, M.; Rajagopal, B.; Syrett, N.; Shaik, T.; Gretton, S.; Welbourn, E.; Bülow, L.; Eriksson, N.L.; Ronda, L.; Mozzarelli, A.; Eke, A.; Mathe, D.; Reeder, B.J. Engineering Tyrosine Residues into Hemoglobin Enhances Heme Reduction, Decreases Oxidative Stress and Increases Vascular Retention of a Hemoglobin Based Blood Substitute. Free Radical Biology & Medicine, 2019, 134, 106–118. doi: 10.1016/j.freeradbiomed.2018.12.030
  274. Le, D.H.T.; Méndez-López, E.; Wang, C.; Commandeur, U.; Aranda, M.A.; Steinmetz, N.F. Biodistribution of Filamentous Plant Virus Nanoparticles: Pepino Mosaic Virus versus Potato Virus X. Biomacromolecules, 2019, 20(1), 469–477. doi: 10.1021/acs.biomac.8b01365
  275. Pirutin, S.K.; Efremova, M.V.; Yusipovich, A.I.; Turovetskii, V.B.; Maksimov, G.V.; Druzhko, A.B.; Mazhuga, A.G. Visualization and Cytotoxicity of Fluorescence-Labeled Dimeric Magnetite-Gold Nanoparticles Conjugated with Prostate-Specific Membrane Antigen in Mouse Macrophages. Bulletin of Experimental Biology and Medicine, 2019, 166(3), 386–389. doi: 10.1007/s10517-019-04356-9
  276. Nguyen, H.T.; Soe, Z.C.; Yang, K.Y.; Phung, C.D.; Nguyen, L.T-T.; Jeong, J.-H.; Jin, S.G.; Choi, H.-G.; Ku, S.K.; Yong, C.S.; Kim, J.O. Transferrin-conjugated pH-sensitive platform for effective delivery of porous palladium nanoparticles and paclitaxel in cancer treatment. Colloids and Surfaces, B: Biointerfaces, 2019, 176, 265–275. doi: 10.1016/j.colsurfb.2019.01.010
  277. Maerle, A.V.; Simonova, M.A.; Pivovarov, V.D.; Voronina, D.V.; Drobyazina, P.E.; Trofimov, D.Y.; Alekseev, L.P.; Zavriev, S.K.; Ryazantsev, D.Y. Development of the covalent antibody-DNA conjugates technology for detection of IgE and IgM antibodies by immuno-PCR. PloS One, 2019, 14(1), e0209860. doi: 10.1371/journal.pone.0209860
  278. Marín-Caba, L.; Chariou, P.L.; Pesquera, C.; Correa-Duarte, M.A.; Steinmetz, N.F. Tobacco Mosaic Virus-Functionalized Mesoporous Silica Nanoparticles, a Wool-Ball-like Nanostructure for Drug Delivery. Langmuir, 2019, 35(1), 203–211. doi: 10.1021/acs.langmuir.8b03337
  279. Lalonde, T.; Shepherd, T.G.; Dhanvantari, S.; Luyt, L.G. Stapled ghrelin peptides as fluorescent imaging probes. Peptide Science, 2019, 111(1), e24055. doi: 10.1002/pep2.24055
  280. Liu, Y.; Wang, Z.; Li, X.; Ma, X.; Wang, S.; Kang, F.; Yang, W.; Ma, W.; Wang, J. Near-infrared Fluorescent Peptides with High Tumor Selectivity: Novel Probes for Image-Guided Surgical Resection of Orthotopic Glioma. Molecular Pharmaceutics, 2019, 16(1), 108–117. doi: 10.1021/acs.molpharmaceut.8b00888
  281. Zhang, S.; Li, Z.-T.; Liu, M.; Wang, J.-R.; Xu, M.-Q.; Li, Z.-Y.; Duan, X.-C.; Hao, Y.-L.; Zheng, X.-C.; Li, H.; Feng, Z.-H.; Zhang, X. Anti-tumour activity of low molecular weight heparin doxorubicin nanoparticles for histone H1 high-expressive prostate cancer PC-3M cells. Journal of Controlled Release, 2019, 295, 102–117. doi: 10.1016/j.jconrel.2018.12.034
  282. Kluender, E.J.; Hedrick, J.L.; Brown, K.A.; Rao, R.; Meckes, B.; Du, J.S.; Moreau, L.M.; Maruyama, B.; Mirkin, C.A. Catalyst discovery through megalibraries of nanomaterials. Proceedings of the National Academy of Sciences of the United States of America, 2019, 116(1), 40–45. doi: 10.1073/pnas.1815358116
  283. Li, Y.; Lu, A.; Long, M.; Cui, L.; Chen, Z.; Zhu, L. Nitroimidazole derivative incorporated liposomes for hypoxia-triggered drug delivery and enhanced therapeutic efficacy in patient-derived tumor xenografts. Acta Biomaterialia, 2019, 83, 334–348. doi: 10.1016/j.actbio.2018.10.029
  284. Hauser-Kawaguchi, A.; Milne, M.; Li, F.; Lee, T.Y.; Luyt, L.G. The development of a near infrared inulin optical probe for measuring glomerular filtration rate. International Journal of Biological Macromolecules, 2019, 123, 255–260. doi: 10.1016/j.ijbiomac.2018.11.034
  285. Li, L.; Yang, J.; Soodvilai, S.; Wang, J.; Opanasopit, P.; Kopeček, J. Drug-free albumin-triggered sensitization of cancer cells to anticancer drugs. Journal of Controlled Release, 2019, 293, 84–93. doi: 10.1016/j.jconrel.2018.11.015
  286. Näkki, S.; Wang, J.T.-W.; Wu, J.; Fan, L.; Rantanen, J.; Nissinen, T.; Kettunen, M.I.; Backholm, M.; Ras, R.H.A.; Al-Jamal, K.T.; Lehto, V.-P.; Xu, W. Designed inorganic porous nanovector with controlled release and MRI features for safe administration of doxorubicin. International Journal of Pharmaceutics, 2019, 554, 327–336. doi: 10.1016/j.ijpharm.2018.10.074
  287. Song, J.Y.; Larson, N.R.; Thati, S.; Torres-Vazquez, I.; Martinez-Rivera, N.; Subelzu-Aispuru, N.J.; Leon, M.A.; Rosa-Molinar, E.; Schöneich, C.; Middaugh, C.R.; Berkland, C.J. Glatiramer acetate persists at the injection site and draining lymph nodes via electrostatically-induced aggregation. Journal of Controlled Release, 2019, 293, 36–47. doi: 10.1016/j.jconrel.2018.11.007
  288. Farzan, V.M.; Kvach, M.V.; Aparin, I.O.; Kireev, D.E.; Prikazchikova, T.A.; Ustinov, A.V.; Shmanai, V.V.; Shipulin, G.A.; Korshun, V.A.; Zatsepin, T.S. Novel homo Yin-Yang probes improve sensitivity in RT-qPCR detection of low copy HIV RNA. Talanta, 2019, 194, 226–232. doi: 10.1016/j.talanta.2018.10.043
  289. Li, Y.; Xiao, Y.; Lin, H.-P.; Reichel, D.; Bae, Y.; Lee, E.Y.; Jiang, Y.; Huang, X.; Yang, C.; Wang, Z. In vivo β-catenin attenuation by the integrin α5-targeting nano-delivery strategy suppresses triple negative breast cancer stemness and metastasis. Biomaterials, 2019, 188, 160–172. doi: 10.1016/j.biomaterials.2018.10.019
  290. Malheiros, J.M.; Braga, C.P.; Grove, R.A.; Ribeiro, F.A.; Calkins, C.R.; Adamec, J.; Chardulo, L.A.L. Influence of oxidative damage to proteins on meat tenderness using a proteomics approach. Meat Science, 2019, 148, 64–71. doi: 10.1016/j.meatsci.2018.08.016

2018

  1. Ye, K.; Sinawang, P.D.; Yoong, A.T.I.; Marks, R.S. Photoinducible silane diazirine as an effective crosslinker in the construction of a chemiluminescent immunosensor targeting a model E. coli analyte. Sensors and Actuators B: Chemical, 2018, 256, 234–242. doi: 10.1016/j.snb.2017.10.058
  2. Norred, S.E.; Dabbs, R.M.; Chauhan, G.; Caveney, P.M.; Collier, C.P.; Abel, S.M.; Simpson, M.L. Synergistic interactions between confinement and macromolecular crowding spatially order transcription and translation in cell-free expression. bioRxiv, 2018, preprint. doi: 10.1101/445544
  3. Bond, M.J.; Bleiler, M.; Harrison, L.E.; Scocchera, E.W.; Nakanishi, M.; G-Dayanandan, N.; Keshipeddy, S.; Rosenberg, D.W.; Wright, D.L.; Giardina, C. Spindle assembly disruption and cancer cell apoptosis with a CLTC-binding compound. Molecular Cancer Research, 2018, 16(9), 1361–1372. doi: 10.1158/1541-7786.MCR-18-0178
  4. Doh, J.K.; White, J.D.; Zane, H.K.; Chang, Y.H.; López, C.S.; Enns, C.A.; Beatty, K.E. VIPER is a genetically encoded peptide tag for fluorescence and electron microscopy. Proceedings of the National Academy of Sciences of the United States of America, 2018, 115, 12961–12966. doi: 10.1073/pnas.1808626115
  5. Smith, W.J.; Wang, G.; Gaikwad, H.; Vu, V.P.; Groman, E.; Bourne, D.W.A.; Simberg, D. Accelerated Blood Clearance of Antibodies by Nanosized Click Antidotes. ACS Nano, 2018, 12(12), 12523–12532. doi: 10.1021/acsnano.8b07003
  6. Chen, G.; Ma, B.; Xie, R.; Wang, Y.; Dou, K.; Gong, S. NIR-induced spatiotemporally controlled gene silencing by upconversion nanoparticle-based siRNA nanocarrier. Journal of Controlled Release, 2018, 282, 148–155. doi: 10.1016/j.jconrel.2017.12.028
  7. Rink, W.M.; Thomas, F. Decoration of Coiled-Coil Peptides with N-Cysteine Peptide Thioesters As Cyclic Peptide Precursors Using Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC) Click Reaction. Organic Letters, 2018, 20(23), 7493–7497. doi: 10.1021/acs.orglett.8b03261
  8. Wang, Z.; Zhang, R.X.; Zhang, T.; He, C.; He, R.; Ju, X.; Wu, X.Y. In Situ Proapoptotic Peptide-Generating Rapeseed Protein-Based Nanocomplexes Synergize Chemotherapy for Cathepsin-B Overexpressing Breast Cancer. ACS Applied Materials & Interfaces, 2018, 10(48), 41056–41069. doi: 10.1021/acsami.8b14001
  9. Shi, M.; Chen, B.; Mahajan, D.; Boh, B.K.; Zhou, Y.; Dutta, B.; Tie, H.C.; Sze, S.K.; Wu, G.; Lu, L. Amino acids stimulate the endosome-to-Golgi trafficking through Ragulator and small GTPase Arl5. Nature Communications, 2018, 9, 4987. doi: 10.1038/s41467-018-07444-y
  10. Crupi, A.N.; Nunnelee, J.S.; Taylor, D.J.; Thomas, A.; Vit, J.-P.; Riera, C.E.; Gottlieb, R.A.; Goodridge, H.S. Oxidative muscles have better mitochondrial homeostasis than glycolytic muscles throughout life and maintain mitochondrial function during aging. Aging, 2018, 10(11), 3327–3352. doi: 10.18632/aging.101643
  11. Shih, F.-Y.; Su, I.-J.; Chu, L.-L.; Lin, X.; Kuo, S.-C.; Hou, Y.-C.; Chiang, Y.-T. Development of Pectin-Type B Gelatin Polyelectrolyte Complex for Curcumin Delivery in Anticancer Therapy. International Journal of Molecular Sciences, 2018, 19, E3625. doi: 10.3390/ijms19113625
  12. Li, Z.; Behrens, A.M.; Ginat, N.; Tzeng, S.Y.; Lu, X.; Sivan, S.; Langer, R.; Jaklenec, A. Biofilm-Inspired Encapsulation of Probiotics for the Treatment of Complex Infections. Advanced Materials, 2018, 30(51), e1803925. doi: 10.1002/adma.201803925
  13. Delasoie, J.; Rossier, J.; Haeni, L.; Rothen-Rutishauser, B.; Zobi, F. Slow-targeted release of a ruthenium anticancer agent from vitamin B12 functionalized marine diatom microalgae. Dalton Transactions, 2018, 47(48), 17221–17232. doi: 10.1039/c8dt02914h
  14. van Driessche, A; Kocere, A.; Everaert, H.; Nuhn, L.; van Herck, S.; Griffiths, G.; Fenaroli, F.; de Geest, B.G. pH-sensitive hydrazone-linked doxorubicin nanogels via polymeric activated ester scaffolds: synthesis, assembly, in vitro and in vivo evaluation in tumor bearing zebrafish. Chemistry of Materials, 2018, 30(23), 8587–8596. doi: 10.1021/acs.chemmater.8b03702
  15. Li, L.; Liu, Y.; Li, H.; Guo, X.; He, X.; Geng, S.; Zhao, H.; Peng, X.; Shi, D.; Xiong, B.; Zhou, G.; Zhao, Y.; Zheng, C.; Yang, X. Rational design of temperature-sensitive blood-vessel-embolic nanogels for improving hypoxic tumor microenvironment after transcatheter arterial embolization. Theranostics, 2018, 8(22), 6291–6306. doi: 10.7150/thno.28845
  16. Pawar, G.N.; Parayath, N.N.; Nocera, A.L.; Bleier, B.S.; Amiji, M.M. Direct CNS delivery of proteins using thermosensitive liposome-in-gel carrier by heterotopic mucosal engrafting. PLoS One, 2018, 13, e0208122. doi: 10.1371/journal.pone.0208122
  17. Domljanovic, I.; Hansen, A.H.; Hansen, L.H.; Klitgaard, J.K.; Taskova, M.; Astakhova, K. Studies of Impending Oligonucleotide Therapeutics in Simulated Biofluids. Nucleic Acid Therapeutics, 2018, 28(6), 348–356. doi: 10.1089/nat.2017.0704
  18. Komarova, N.; Andrianova, M.; Glukhov, S.; Kuznetsov, A. Selection, Characterization, and Application of {ssDNA} Aptamer against Furaneol. Molecules, 2018, 23(12), 3159. doi: 10.3390/molecules23123159
  19. Yu, C.; Tang, J.; Loredo, A.; Chen, Y.; Jung, S.Y.; Jain, A.; Gordon, A.; Xiao, H. Proximity-Induced Site-Specific Antibody Conjugation. Bioconjugate Chemistry, 2018, 29(11), 3522–3526. doi: 10.1021/acs.bioconjchem.8b00680
  20. Pitek, A.S.; Hu, H.; Shukla, S.; Steinmetz, N.F. Cancer Theranostic Applications of Albumin-Coated Tobacco Mosaic Virus Nanoparticles. ACS Applied Materials & Interfaces, 2018, 10(46), 39468–39477. doi: 10.1021/acsami.8b12499
  21. Liu, Y.; Li, Q.; Xiong, X.; Huang, Y.; Zhou, Z. Enhanced cellular uptake by non-endocytic pathway for tumor therapy. Journal of Materials Chemistry B, 2018, 6(45), 7411–7419. doi: 10.1039/c8tb01698d
  22. Meena, G.G.; Jain, A.; Parks, J.; Stambaugh, A.; Patterson, J.; Hawkins, A.; Schmidt, H. Integration of sample preparation and analysis on an optofluidic chip for multi-target disease detection. Lab on a Chip, 2018, 18(23), 3678–3686. doi: 10.1039/c8lc00966j
  23. Korzhikov-Vlakh, V.; Averianov, I.; Sinitsyna, E.; Nashchekina, Y.; Polyakov, D.; Guryanov, I.; Lavrentieva, A.; Raddatz, L.; Korzhikova-Vlakh, E.; Scheper, T.; Tennikova, T. Novel Pathway for Efficient Covalent Modification of Polyester Materials of Different Design to Prepare Biomimetic Surfaces. Polymers, 2018, 10(12), 1299. doi: 10.3390/polym10121299
  24. Ranjit, S.; Malacrida, L.; Gratton, E. Differences between FLIM phasor analyses for data collected with the Becker and Hickl SPC830 card and with the FLIMbox card. Microscopy Research and Technique, 2018, 81(9), 980–989. doi: 10.1002/jemt.23061
  25. Zahid, M.; Feldman, K.S.; Garcia-Borrero, G.; Feinstein, T.N.; Pogodzinski, N.; Xu, X.; Yurko, R.; Czachowski, M.; Wu, Y.L.; Mason, N.S.; Lo, C.W. Cardiac Targeting Peptide, a Novel Cardiac Vector: Studies in Bio-Distribution, Imaging Application, and Mechanism of Transduction. Biomolecules, 2018, 8(4), 147. doi: 10.3390/biom8040147
  26. Cui, X.-Y.; Sun, N.-N.; Xie, X.-N.; Sun, W.-C.; Zhao, Q.; Liu, N. Detection of Newly Synthesized Proteins via Metabolic Incorporation of Non-natural Amino Acid. Chinese Journal of Analytical Chemistry, 2018, 46(11), 1808–1813. doi: 10.1016/s1872-2040(18)61125-9
  27. Zhang, L.; Fang, Y.; Li, L.; Yang, J.; Radford, D.C.; Kopeček, J. Human Serum Albumin-Based Drug-Free Macromolecular Therapeutics: Apoptosis Induction by Coiled-Coil-Mediated Cross-Linking of CD20 Antigens on Lymphoma B Cell Surface. Macromolecular Bioscience, 2018, 18(11), e1800224. doi: 10.1002/mabi.201800224
  28. Shim, K.-S.; Kim, H.-J.; Kim, S.E.; Park, K. Simple surface biofunctionalization of biphasic calcium phosphates for improving osteogenic activity and bone tissue regeneration. Journal of Industrial and Engineering Chemistry, 2018, 68, 228–228. doi: 10.1016/j.jiec.2018.07.048
  29. Zhang, Q.; Scigliano, A.; Biver, T.; Pucci, A.; Swager, T.M. Interfacial Bioconjugation on Emulsion Droplet for Biosensors. Bioorganic & Medicinal Chemistry, 2018, 26(19), 5307–5313. doi: 10.1016/j.bmc.2018.04.020
  30. Ng, S.; Bennett, N.J.; Schulze, J.; Gao, N.; Rademacher, C.; Derda, R. Genetically-encoded Fragment-based Discovery of Glycopeptide Ligands for DC-SIGN. Bioorganic & Medicinal Chemistry, 2018, 26(19), 5368–5377. doi: 10.1016/j.bmc.2018.08.036
  31. Yang, J.; Xu, J.; Gonzalez, R.; Lindner, T.; Kratochwil, C.; Miao, Y. 68Ga-DOTA-GGNle-CycMSHhex targets the melanocortin-1 receptor for melanoma imaging. Science Translational Medicine, 2018, 10(466), eaau4445. doi: 10.1126/scitranslmed.aau4445
  32. Swenson, S.; Minea, R.O.; Tuan, C.D.; Thein, T.-Z.; Chen, T.C.; Markland, F.S. A Novel Venom-Derived Peptide for Brachytherapy of Glioblastoma: Preclinical Studies in Mice. Molecules, 2018, 23(11), 2918. doi: 10.3390/molecules23112918
  33. Swaminathan, J.; Boulgakov, A.A.; Hernandez, E.T.; Bardo, A.M.; Bachman, J.L.; Marotta, J.; Johnson, A.M.; Anslyn, E.V.; Marcotte, E.M. Highly parallel single-molecule identification of proteins in zeptomole-scale mixtures. Nature Biotechnology, 2018, 36(11), 1076–1082. doi: 10.1038/nbt.4278
  34. Alferova, V.A.; Shuvalov, M.V.; Suchkova, T.A.; Proskurin, G.V.; Aparin, I.O.; Rogozhin, E.A.; Novikov, R.A.; Solyev, P.N.; Chistov, A.A.; Ustinov, A.V.; Tyurin, A.P.; Korshun, V.A. 4-Chloro-L-kynurenine as fluorescent amino acid in natural peptides. Amino Acids, 2018, 50(12), 1697–1705. doi: 10.1007/s00726-018-2642-3
  35. Qiao, R.; Esser, L.; Fu, C.; Zhang, C.; Hu, J.; Ramírez-García, P.; Li, Y.; Quinn, J.F.; Whittaker, M.R.; Whittaker, A.K.; Davis, T.P. Bioconjugation and Fluorescence Labelling of Iron Oxide Nanoparticles Grafted with Bromomaleimide-terminal Polymers. Biomacromolecules, 2018, 19(11), 4423–4429. doi: 10.1021/acs.biomac.8b01282
  36. Nuhn, L.; De Koker, S.; Van Lint, S.; Zhong, Z.; Catani, J.P.; Combes, F.; Deswarte, K.; Li, Y.; Lambrecht, B.N.; Lienenklaus, S.; Sanders, N.N.; David, S.A.; Tavernier, J.; De Geest, B.G. Nanoparticle-Conjugate TLR7/8 Agonist Localized Immunotherapy Provokes Safe Antitumoral Responses. Advanced Materials, 2018, 30(45), e1803397. doi: 10.1002/adma.201803397
  37. Lee, S.Y.; Ko, S.-H.; Shim, J.-S.; Kim, D.-D.; Cho, H.-J. Tumor Targeting and Lipid Rafts Disrupting Hyaluronic Acid-Cyclodextrin-Based Nanoassembled Structure for Cancer Therapy. ACS Applied Materials & Interfaces, 2018, 10(43), 36628–36640. doi: 10.1021/acsami.8b08243
  38. Konopka, C.J.; Wozniak, M.; Hedhli, J.; Ploska, A.; Schwartz-Duval, A.; Siekierzycka, A.; Pan, D.; Munirathinam, G.; Dobrucki, I.T.; Kalinowski, L.; Dobrucki, L.W. Multimodal imaging of the receptor for advanced glycation end-products with molecularly targeted nanoparticles. Theranostics, 2018, 8(18), 5012–5024. doi: 10.7150/thno.24791
  39. van Herck, S.; Deswarte, K.; Nuhn, L.; Zhong, Z.; Portela Catani, J.P.; Li, Y.; Sanders, N.N.; Lienenklaus, S.; De Koker, S.; Lambrecht, B.N.; David, S.A.; De Geest, B.G. Lymph-Node-Targeted Immune Activation by Engineered Block Copolymer Amphiphiles-TLR7/8 Agonist Conjugates. Journal of the American Chemical Society, 2018, 140, 14300–14307. doi: 10.1021/jacs.8b08595
  40. Arevalo-Martin, A.; Grassner, L.; Garcia-Ovejero, D.; Paniagua-Torija, B.; Barroso-Garcia, G.; Arandilla, A.G.; Mach, O.; Turrero, A.; Vargas, E.; Alcobendas, M.; Rosell, C.; Alcaraz, M.A.; Ceruelo, S.; Casado, R.;Talavera, F.; Palazón, R.; Sanchez-Blanco, N.; Maier, D.; Esclarin, A.; Molina-Holgado, E. Elevated Autoantibodies in Subacute Human Spinal Cord Injury Are Naturally Occurring Antibodies. Frontiers in Immunology, 2018, 9, 2365. doi: 10.3389/fimmu.2018.02365
  41. Segal, E.S.; Gritsenko, V.; Levitan, A.; Yadav, B.; Dror, N.; Steenwyk, J.L.; Silberberg, Y.; Mielich, K.; Rokas, A.; Gow, N.A.R.; Kunze, R.; Sharan, R.; Berman, J. Gene Essentiality Analyzed by In Vivo Transposon Mutagenesis and Machine Learning in a Stable Haploid Isolate of Candida albicans. mBio, 2018, 9(5), e02048-18. doi: 10.1128/mBio.02048-18
  42. Hyun, J.Y.; Kim, S.; Lee, H.S.; Shin, I. A Glycoengineered Enzyme with Multiple Mannose-6-Phosphates Is Internalized into Diseased Cells to Restore Its Activity in Lysosomes. Cell Chemical Biology, 2018, 25(10), 1255–1267.e8. doi: 10.1016/j.chembiol.2018.07.011
  43. Ishihara, J.; Ishihara, A.; Potin, L.; Hosseinchi, P.; Fukunaga, K.; Damo, M.; Gajewski, T.F.; Swartz, M.A.; Hubbell, J.A. Improving Efficacy and Safety of Agonistic Anti-CD40 Antibody Through Extracellular Matrix Affinity. Molecular Cancer Therapeutics, 2018, 17(11), 2399–2411. doi: 10.1158/1535-7163.MCT-18-0091
  44. Joo, J.; Poon, C.; Yoo, S.P.; Chung, E.J. Shape Effects of Peptide Amphiphile Micelles for Targeting Monocytes. Molecules, 2018, 23(11), 2786. doi: 10.3390/molecules23112786
  45. Bellat, V.; Ting, R.; Southard, T.L.; Vahdat, L.; Molina, H.; Fernandez, J.; Aras, O.; Stokol, T.; Law, B. Functional Peptide Nanofibers with Unique Tumor Targeting and Enzyme-Induced Local Retention Properties. Advanced Functional Materials, 2018, 28(44), 1803969. doi: 10.1002/adfm.201803969
  46. Zhang, J.; Chetnani, B.; Cormack, E.D.; Alonso, D.; Liu, W.; Mondragon, A.; Fei, J. Specific structural elements of the T-box riboswitch drive the two-step binding of the tRNA ligand. eLife, 2018, 7, e39518. doi: 10.7554/eLife.39518
  47. Smith, J.D.; Cardwell, L.N.; Porciani, D.; Nguyen, J.A.; Gallazzi, F.; Tata, R.R.; Burke, D.H.; Daniels, M.A.; Ulery, B. Aptamer-displaying peptide amphiphile micelles as a cell-targeted delivery vehicle of peptide cargoes. Physical Biology, 2018, 15(6), 065006. doi: 10.1088/1478-3975/aadb68
  48. Stefaniak, J.; Lewis, A.M.; Conole, D.; Galan, S.R.G.; Bataille, C.J.R.; Wynne, G.M.; Castaldi, M.P.; Lundbäck, T.; Russell, A.J.; Huber, K.V.M. Chemical Instability and Promiscuity of Arylmethylidenepyrazolinone-Based MDMX Inhibitors. ACS Chemical Biology, 2018, 13(10), 2849–2854. doi: 10.1021/acschembio.8b00665
  49. Lee, K.; Yu, Y. Lipid Bilayer Disruption by Amphiphilic Janus Nanoparticles: The Role of Janus Balance. Langmuir, 2018, 34(41), 12387–12393. doi: 10.1021/acs.langmuir.8b02298
  50. Gurnani, Pratik and Sanchez-Cano, C.; Abraham, K.; Xandri-Monje, H.; Cook, A.B.; Hartlieb, M.; Lévi, F.; Dallmann, R.; Perrier, S. RAFT Emulsion Polymerization as a Platform to Generate Well-Defined Biocompatible Latex Nanoparticles. Macromolecular Bioscience, 2018, 18(10), e1800213. doi: 10.1002/mabi.201800213
  51. Wu, B.; Zhang, H.; Sun, R.; Peng, S.; Cooperman, B.S.; Goldman, Y.E.; Chen, C. Translocation kinetics and structural dynamics of ribosomes are modulated by the conformational plasticity of downstream pseudoknots. Nucleic Acids Research, 2018, 46(18), 9736–9748. doi: 10.1093/nar/gky636
  52. Khang, M.K.; Zhou, J.; Huang, Y.; Hakamivala, A.; Tang, L. Preparation of a novel injectable in situ-gelling nanoparticle with applications in controlled protein release and cancer cell entrapment. RSC Advances, 2018, 8(60), 34625–34633. doi: 10.1039/c8ra06589f
  53. Lufton, M.; Bustan, O.; Eylon, B.-h.; Shtifman-Segal, E.; Croitoru-Sadger, T.; Shagan, A.; Shabtay-Orbach, A.; Corem-Salkmon, E.; Berman, J.; Nyska, A.; Mizrahi, B. Living Bacteria in Thermoresponsive Gel for Treating Fungal Infections. Advanced Functional Materials, 2018, 28(40), 1801581. doi: 10.1002/adfm.201801581
  54. Li, W.; Li, Y.; Liu, Z.; Kerdsakundee, N.; Zhang, M.; Zhang, F.; Liu, X.; Bauleth-Ramos, T.; Lian, W.; Mäkilä, E.; Kemell, M.; Ding, Y.; Sarmento, B.; Wiwattanapatapee, R.; Salonen, J.; Zhang, H.; Hirvonen, J.T.; Liu, D.; Deng, X.; Santos, H.A. Hierarchical structured and programmed vehicles deliver drugs locally to inflamed sites of intestine. Biomaterials, 2018, 185, 322–332. doi: 10.1016/j.biomaterials.2018.09.024
  55. Besford, Q.A.; Ju, Y.; Wang, T.-Y.; Yun, G.; Cherepanov, P.V.; Hagemeyer, C.E.; Cavalieri, F.; Caruso, F. Self-Assembled Metal-Phenolic Networks on Emulsions as Low-Fouling and pH-Responsive Particles. Small, 2018, 14(39), e1802342. doi: 10.1002/smll.201802342
  56. Kumar, R.; Welle, A.; Becker, F.; Kopyeva, I.; Lahann, J. Substrate-Independent Micropatterning of Polymer Brushes Based on Photolytic Deactivation of Chemical Vapor Deposition Based Surface-Initiated Atom-Transfer Radical Polymerization Initiator Films. Applied Materials & Interfaces, 2018, 10(38), 31965–31976. doi: 10.1021/acsami.8b11525
  57. van Hall-Beauvais, A.; Zhao, Y.; Urul, D.A.; Long, M.J.C.; Aye, Y. Single-Protein-Specific Redox Targeting in Live Mammalian Cells and C. elegans. Current Protocols in Chemical Biology, 2018, 10(3), e43. doi: 10.1002/cpch.43
  58. Mickuté, M.; Nainyté, M.; Vasiliauskaité, L.; Plotnikova, A.; Masevičius, V.; Klimašauskas, S.; Vilkaitis, G. Animal Hen1 2'-O-methyltransferases as tools for 3'-terminal functionalization and labelling of single-stranded RNAs. Nucleic Acids Research, 2018, 46(17), e104. doi: 10.1093/nar/gky514
  59. Etrych, T.; Daumová, L.; Pokorná, E.; Tušková, D.; Lidický, O.; Kolářová, V.; Pankrác, J.; Šefc, L.; Chytil, P.; Klener, P. Effective doxorubicin-based nano-therapeutics for simultaneous malignant lymphoma treatment and lymphoma growth imaging. Journal of Controlled Release, 2018, 289, 44–55. doi: 10.1016/j.jconrel.2018.09.018
  60. Eelen, G.; Dubois, C.; Cantelmo, A.R.; Goveia, J.; Brüning, U.; DeRan, M.; Jarugumilli, G.; van Rijssel, J.; Saladino, G.; Comitani, F.; Zecchin, A.; Rocha, S.; Chen, R.; Huang, H.; Vandekeere, S.; Kalucka, J.; Lange, C.; Morales-Rodriguez, F.; Cruys, B.; Treps, L.; Ramer, L.; Vinckier, S.; Brepoels, K.; Wyns, S.; Souffreau, J.; Schoonjans, L.; Lamers, W.H.; Wu, Y.; Haustraete, J.; Hofkens, J.; Liekens, S.; Cubbon, R.; Ghesquière, B.; Dewerchin, M.; Gervasio, F.L.; Li, X.; van Buul, J.D.; Wu, X.; Carmeliet, P. Role of glutamine synthetase in angiogenesis beyond glutamine synthesis. Nature, 2018, 561(7721), 63–69. doi: 10.1038/s41586-018-0466-7
  61. Fu, Y.; Long, M.J.C.; Wisitpitthaya, S.; Inayat, H.; Pierpont, T.M.; Elsaid, I.M.; Bloom, J.C.; Ortega, J.; Weiss, R.S.; Aye, Y. Nuclear RNR-α antagonizes cell proliferation by directly inhibiting ZRANB3. Nature Chemical Biology, 2018, 14(10), 943–954. doi: 10.1038/s41589-018-0113-5
  62. Braselmann, E.; Wierzba, A.J.; Polaski, J.T.; Chromiński, M.; Holmes, Z.E.; Hung, S.-T.; Batan, D.; Wheeler, J.R.; Parker, R.; Jimenez, R.; Gryko, D.; Batey, R.T.; Palmer, A.E. A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells. Nature Chemical Biology, 2018, 14(10), 964–971. doi: 10.1038/s41589-018-0103-7
  63. Ta, D.T.; Vanella, R.; Nash, M.A. Bioorthogonal Elastin-like Polypeptide Scaffolds for Immunoassay Enhancement. ACS Applied Materials & Interfaces, 2018, 10(36), 30147–30154. doi: 10.1021/acsami.8b10092
  64. Xu, H.; Bandari, R.; Lee, L.E.; Li, R.; Yu, P.; Smith, C.J.; Ma, L. Design, Synthesis, and In Vitro and In Vivo Evaluation of High Affinity and Specificity Near-Infrared Fluorescent Bombesin Antagonists for Tumor Imaging. Journal of Medicinal Chemistry, 2018, 61(17), 7657–7670. doi: 10.1021/acs.jmedchem.8b00614
  65. Wang, Y.; Li, L.; Zhao, W.; Dou, Y.; An, H.; Tao, H.; Xu, X.; Jia, Y.; Lu, S.; Zhang, J.; Hu, H. Targeted Therapy of Atherosclerosis by a Broad-Spectrum Reactive Oxygen Species-Scavenging Nanoparticle with Intrinsic Anti-Inflammatory Activity. ACS Nano, 2018, 12(9), 8943–8960. doi: 10.1021/acsnano.8b02037
  66. Gomez, I.J.; Arnaiz, B.; Cacioppo, M.; Arcudi, F.; Prato, M. Nitrogen-doped Carbon Nanodots for bioimaging and delivery of paclitaxel. Journal of Materials Chemistry B, 2018, 6(35), 5540–5548. doi: 10.1039/c8tb01796d
  67. Zhang, C.; Moonshi, S.S.; Wang, W.; Ta, H.T.; Han, Y.; Han, F.Y.; Peng, H.; Král, P.; Rolfe, B.E.; Gooding, J.J.; Gaus, K.; Whittaker, A.K. High F-Content Perfluoropolyether-Based Nanoparticles for Targeted Detection of Breast Cancer by 19F Magnetic Resonance and Optical Imaging. ACS Nano, 2018, 12(9), 9162–9176. doi: 10.1021/acsnano.8b03726
  68. Pitek, A.S.; Park, J.; Wang, Y.; Gao, H.; Hu, H.; Simon, D.I.; Steinmetz, N.F. Delivery of thrombolytic therapy using rod-shaped plant viral nanoparticles decreases the risk of hemorrhage. Nanoscale, 2018, 10(35), 16547–16555. doi: 10.1039/c8nr02861c
  69. Zadeh, P.S.N.; do Valle Gomes, M.Z.; Abrahamsson, M.; Palmqvist, A.; Åkerman, B. Measuring Viscosity inside Mesoporous Silica Using Protein-Bound Molecular Rotor Probe. Physical Chemistry Chemical Physics, 2018, 20(36), 23202–23213. doi: 10.1039/C8CP01063C
  70. Spangler, B.; Dovala, D.; Sawyer, W.S.; Thompson, K.V.; Six, D.A.; Reck, F.; Feng, B.Y. Molecular probes for the determination of sub-cellular compound exposure profiles in Gram-negative bacteria. ACS Infectious Diseases, 2018, 4(9), 1355–1367. doi: 10.1021/acsinfecdis.8b00093
  71. Graham, T.G.W.; Carney, S.M.; Walter, J.C.; Loparo, J.J. A single XLF dimer bridges DNA ends during nonhomologous end joining. Nature Structural & Molecular Biology, 2018, 25(9), 877–884. doi: 10.1038/s41594-018-0120-y
  72. Zhao, Y.; Fletcher, N.L.; Liu, T.; Gemmell, A.C.; Houston, Z.H.; Blakey, I.; Thurecht, K.J. In vivo therapeutic evaluation of polymeric nanomedicines: effect of different targeting peptides on therapeutic efficacy against breast cancer. Nanotheranostics, 2018, 2(4), 360–370. doi: 10.7150/ntno.27142
  73. Karas, J.; Turner, B.J.; Shabanpoor, F. The Assembly of Fluorescently Labeled Peptide-Oligonucleotide Conjugates via Orthogonal Ligation Strategies. Methods in Molecular Biology, 2018, 1282, 355–363. doi: 10.1007/978-1-4939-8651-4_22
  74. Moon, C.H.; Lee, J.Y.; Kim, E.S.; Park, J.H.; Kim, S.-Y.; Kim, J.Y.; Tchah, H. In vivo biodistribution of topical low molecular weight heparin-taurocholate in a neovascularized mouse cornea. International Journal of Ophthalmology, 2018, 11(9), 1435–1439. doi: 10.18240/ijo.2018.09.01
  75. Zhang, Y.; Guo, Z.; Cao, Z.; Zhou, W.; Zhang, Y.; Chen, Q.; Lu, Y.; Chen, X.; Guo, Q.; Li, C.; Liang, D.; Sun, T.; Jiang, C. Endogenous albumin-mediated delivery of redox-responsive paclitaxel-loaded micelles for targeted cancer therapy. Biomaterials, 2018, 183, 243–257. doi: 10.1016/j.biomaterials.2018.06.002
  76. Moynihan, K.D.; Holden, R.L.; Mehta, N.K.; Wang, C.; Karver, M.R.; Dinter, J.; Liang, S.; Abraham, W.; Melo, M.B.; Zhang, A.Q.; Li, N.; Le Gall, S.; Pentelute, B.; Irvine, D.J. Enhancement of peptide vaccine immunogenicity by increasing lymphatic drainage and boosting serum stability. Cancer Immunology Research, 2018, 6(9), 1025–1038. doi: 10.1158/2326-6066.CIR-17-0607
  77. Babos, G.; Biró, E.; Meiczinger, M.; Feczkó, T. Dual Drug Delivery of Sorafenib and Doxorubicin from PLGA and PEG-PLGA Polymeric Nanoparticles. Polymers, 2018, 10(8), 895. doi: 10.3390/polym10080895
  78. Delcanale, P.; Miret-Ontiveros, B.; Arista-Romero, M.; Pujals, S.; Albertazzi, L. Nanoscale Mapping Functional Sites on Nanoparticles by Points Accumulation for Imaging in Nanoscale Topography (PAINT). ACS Nano, 2018, 12(8), 7629–7637. doi: 10.1021/acsnano.7b09063
  79. Henderson, L.; Neumann, O.; Kaffes, C.; Zhang, R.; Marangoni, V.; Ravoori, M.K.; Kundra, V.; Bankson, J.; Nordlander, P.; Halas, N.J. Routes to Potentially Safer T1 Magnetic Resonance Imaging Contrast in a Compact Plasmonic Nanoparticle with Enhanced Fluorescence. ACS Nano, 2018, 12(8), 8214–8223. doi: 10.1021/acsnano.8b03368
  80. Xu, C.; Wang, Y.; Yu, H.; Tian, H.; Chen, X. Multifunctional Theranostic Nanoparticles Derived from Fruit-Extracted Anthocyanins with Dynamic Disassembly and Elimination Abilities. ACS Nano, 2018, 12(8), 8255–8265. doi: 10.1021/acsnano.8b03525
  81. Melnychuk, N.; Klymchenko, A.S. DNA-Functionalized Dye-Loaded Polymeric Nanoparticles: Ultrabright FRET Platform for Amplified Detection of Nucleic Acids. Journal of the American Chemical Society, 2018, 140(34), 10856–10865. doi: 10.1021/jacs.8b05840
  82. Lomakin, Y.; Kudriaeva, A.; Kostin, N.; Terekhov, S.; Kaminskaya, A.; Chernov, A.; Zakharova, M.; Ivanova, M.; Simaniv, T.; Telegin, G.; Gabibov, A.; Belogurov, A. Diagnostics of autoimmune neurodegeneration using fluorescent probing. Scientific Reports, 2018, 8, 12679. doi: 10.1038/s41598-018-30938-0
  83. Tridgett, M.; Moore-Kelly, C.; Duprey, J.-L.H.A.; Iturbe, L.O.; Tsang, C.W.; Little, H.A.; Sandhu, S.K.; Hicks, M.R.; Dafforn, T.R.; Rodger, A. Linear dichroism of visible-region chromophores using M13 bacteriophage as an alignment scaffold. RSC Advances, 2018, 8(52), 29535–29543. doi: 10.1039/c8ra05475d
  84. Khor, S.Y.; Vu, M.N.; Pilkington, E.H.; Johnston, A.P.R.; Whittaker, M.R.; Quinn, J.F.; Truong, N.P.; Davis, T.P. Elucidating the Influences of Size, Surface Chemistry, and Dynamic Flow on Cellular Association of Nanoparticles Made by Polymerization-Induced Self-Assembly. Small, 2018, 14(34), e1801702. doi: 10.1002/smll.201801702
  85. Schrand, B.; Clark, E.; Levay, A.; Capote, A.R.; Martinez, O.; Brenneman, R.; Castro, I.; Gilboa, E. Hapten-mediated recruitment of polyclonal antibodies to tumors engenders antitumor immunity. Nature Communications, 2018, 9, 3348. doi: 10.1038/s41467-018-05566-x
  86. Razgoniaeva, N.; Rogers, S.; Moroz, P.; Cassidy, J.; Zamkov, M. Improving the spectral resolution in fluorescence microscopy through shaped-excitation imaging. Methods and Applications in Fluorescence, 2018, 6(4), 045006. doi: 10.1088/2050-6120/aad81c
  87. Lv, J.; He, B.; Yu, J.; Wang, Y.; Wang, C.; Zhang, S.; Wang, H.; Hu, J.; Zhang, Q.; Cheng, Y. Fluoropolymers for intracellular and in vivo protein delivery. Biomaterials, 2018, 182, 167–175. doi: 10.1016/j.biomaterials.2018.08.023
  88. Lin, P.-Y.; Chiu, Y.-L.; Huang, J.-H.; Chuang, E.-Y.; Mi, F.-L.; Lin, K.-J.; Juang, J.-H.; Sung, H.-W.; Leong, K.W. Oral Nonviral Gene Delivery for Chronic Protein Replacement Therapy. Advanced Science, 2018, 5(8), 1701079. doi: 10.1002/advs.201701079
  89. Jin, Y.N.; Schlueter, P.J.; Jurisch-Yaksi, N.; Lam, P.-Y.; Jin, S.; Hwang, W.Y.; Yeh, J.-R.J.; Yoshigi, M.; Ong, S.-E.; Schenone, M.; Hartigan, C.R.; Carr, S.A.; Peterson, R.T. Noncanonical translation via deadenylated 3' UTRs maintains primordial germ cells. Nature Chemical Biology, 2018, 14(9), 844–852. doi: 10.1038/s41589-018-0098-0
  90. Machová, D.; Koziolová, E.; Chytil, P.; Venclíková, K.; Etrych, T.; Janoušková, O. Nanotherapeutics with suitable properties for advanced anticancer therapy based on HPMA copolymer-bound ritonavir via pH-sensitive spacers. European Journal of Pharmaceutics and Biopharmaceutics, 2018, 131, 141–150. doi: 10.1016/j.ejpb.2018.07.023
  91. Joshi, B.P.; Hardie, J.; Mingroni, M.A.; Farkas, M.E. Surface-Modified Macrophages Facilitate Tracking of Breast Cancer-Immune Interactions. ACS Chemical Biology, 2018, 13(8), 2339–2346. doi: 10.1021/acschembio.8b00509
  92. Navarro, L.A.; French, D.L.; Zauscher, S. Synthesis of Modular Brush Polymer-Protein Hybrids using Diazotransfer and Copper Click Chemistry. Bioconjugate Chemistry, 2018, 29(8), 2594–2605. doi: 10.1021/acs.bioconjchem.8b00309
  93. Babič, A.; Vinet, L.; Chellakudam, V.; Janikowska, K.; Allémann, E.; Lange, N. Squalene-PEG-exendin as high-affinity constructs for pancreatic beta-cells. Bioconjugate Chemistry, 2018, 29(8), 2531–2540. doi: 10.1021/acs.bioconjchem.8b00186
  94. Luthman, A.S. Wide-Field fHSI with a Linescan SRDA. In: Spectrally Resolved Detector Arrays for Multiplexed Biomedical Fluorescence Imaging (Springer Thesis), 2018, 51–85. doi: 10.1007/978-3-319-98255-7_3
  95. Melgar-Asensio, I.; Kandela, I.; Aird, F.; Darjatmoko, S.R.; de Los Rios, C.; Sorenson, C.M.; Albert, D.M.; Sheibani, N.; Henkin, J. Extended Intravitreal Rabbit Eye Residence of Nanoparticles Conjugated With Cationic Arginine Peptides for Intraocular Drug Delivery: In Vivo Imaging. Investigative Ophthalmology & Visual Science, 2018, 59(10), 4071–4081. doi: 10.1167/iovs.18-24087
  96. Gu, R.; Oweida, T.; Yingling, Y.G.; Chilkoti, A.; Zauscher, S. Enzymatic synthesis of nucleobase-modified single-stranded DNA offers tunable resistance to nuclease degradation. Biomacromolecules, 2018, 19(8), 3525–3535. doi: 10.1021/acs.biomac.8b00816
  97. Meka, R.R.; Venkatesha, S.H.; Moudgil, K.D. Peptide-directed liposomal delivery improves the therapeutic index of an immunomodulatory cytokine in controlling autoimmune arthritis. Journal of Controlled Release, 2018, 286, 279–288. doi: 10.1016/j.jconrel.2018.08.007
  98. Santra, K.; Clark, K.D.; Maity, N.; Petrich, J.W.; Anderson, J.L. Exploiting Fluorescence Spectroscopy to Identify Magnetic Ionic Liquids Suitable for the Isolation of Oligonucleotides. The Journal of Physical Chemistry B, 2018, 122(31), 7747–7756. doi: 10.1021/acs.jpcb.8b05580
  99. Lu, Z.; Huang, F.-Y.; Cao, R.; Tan, G.-H.; Yi, G.; He, N.; Xu, L.; Zhang, L. Intrinsic, cancer cell-selective toxicity of organic photothermal nano-agent: a simple formulation for combined photothermal-chemotherapy of cancer. ACS Applied Materials & Interfaces, 2018, 10(31), 26028–26038. doi: 10.1021/acsami.8b07801
  100. Lu, J.; Tang, M.; Liu, Y.; Wang, J.; Wu, Z. Comparative Proteomics of Chromium-Transformed Beas-2B Cells by 2D-DIGE and MALDI-TOF/TOF MS. Biological Trace Element Research, 2018, 185(1), 78–88. doi: 10.1007/s12011-017-1222-9
  101. Kumar, P.; Kuhlmann, F.M.; Chakroborty, S.; Bourgeois, A.L.; Foulke-Abel, J.; Tumala, B.; Vickers, T.J.; Sack, D.A.; DeNearing, B.; Harro, C.D.; Wright, W.S.; Gildersleeve, J.C.; Ciorba, M.A.; Santhanam, S.; Porter, C.K.; Gutierrez, R.L.; Prouty, M.G.; Riddle, M.S.; Polino, A.; Sheikh, A.; Donowitz, M.; Fleckenstein, J.M. Enterotoxigenic Escherichia coli blood group A interactions intensify diarrheal severity. The Journal of Clinical Investigation, 2018, 128(8), 3298–3311. doi: 10.1172/JCI97659
  102. Pivovarov, V.D.; Ryazantsev, D.Y.; Simonova, M.A.; Yegorova, T.V.; Khlgatian, S.V.; Zavriev, S.K.; Svirshchevskaya, E.V. Immuno-PCR Assay for Quantitation of Antibodies to Epstein-Barr Virus. Molecular Biology, 2018, 52(4), 629–635. doi: 10.1134/S0026893318040155
  103. Barry, R.; John, S.W.; Liccardi, G.; Tenev, T.; Jaco, I.; Chen, C.-H.; Choi, J.; Kasperkiewicz, P.; Fernandes-Alnemri, T.; Alnemri, E.; Drag, M.; Chen, Y.; Meier, P. SUMO-mediated regulation of NLRP3 modulates inflammasome activity. Nature Communications, 2018, 9, 3001. doi: 10.1038/s41467-018-05321-2
  104. Li, W.; Zhou, Y.; Tang, G.; Wong, N.-K.; Yang, M.; Tan, D.; Xiao, Y. Chemoproteomics Reveals the Anti-proliferative Potential of Parkinson's Disease Kinase Inhibitor LRRK2-IN-1 by Targeting PCNA Protein. Molecular Pharmaceutics, 2018, 15(8), 3252–3259. doi: 10.1021/acs.molpharmaceut.8b00325
  105. Franke, C.E.; Czapar, A.E.; Patel, R.B.; Steinmetz, N.F. Tobacco Mosaic Virus-Delivered Cisplatin Restores Efficacy in Platinum-Resistant Ovarian Cancer Cells. Molecular Pharmaceutics, 2018, 15(8), 2922–2931. doi: 10.1021/acs.molpharmaceut.7b00466
  106. Zadeh, P.S.N.; do Valle Gomes, M.Z.; Åkerman, B.; Palmqvist, A.E.C. Förster resonance energy transfer study of the improved biocatalytic conversion of CO2 to formaldehyde by co-immobilization of enzymes in siliceous mesostructured cellular foams. ACS Catalysis, 2018, 8(8), 7251–7260. doi: 10.1021/acscatal.8b01806
  107. Jones, J.E.; Busi, S.B.; Mitchem, J.B.; Amos-Landgraf, J.M.; Lewis, M.R. Evaluation of a Tumor-Targeting, Near-Infrared Fluorescent Peptide for Early Detection and Endoscopic Resection of Polyps in a Rat Model of Colorectal Cancer. Molecular Imaging, 2018, 17, 1536012118790065. doi: 10.1177/1536012118790065
  108. Dutta, D.; Lai, K.-Y.; Reyes-Ordoñez, A.; Chen, J.; van der Donk, W.A. Lanthionine synthetase C-like protein 2 (LanCL2) is Important for Adipogenic Differentiation. Journal of Lipid Research, 2018, 59(8), 1433–1445. doi: 10.1194/jlr.M085274
  109. Nuhn, L.; Van Hoecke, L.; Deswarte, K.; Schepens, B.; Li, Y.; Lambrecht, B.N.; De Koker, S.; David, S.A.; Saelens, X.; De Geest, B.G. Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist. Biomaterials, 2018, 178, 643–651. doi: 10.1016/j.biomaterials.2018.03.026
  110. Liu, G.W.; Prossnitz, A.N.; Eng, D.G.; Cheng, Y.; Subrahmanyam, N.; Pippin, J.W.; Lamm, R.J.; Ngambenjawong, C.; Ghandehari, H.; Shankland, S.J.; Pun, S.H. Glomerular disease augments kidney accumulation of synthetic anionic polymers. Biomaterials, 2018, 178, 317–325. doi: 10.1016/j.biomaterials.2018.06.001
  111. Shvadchak, V.; Zgheib, S.; Basta, B.; Humbert, N.; Langedijk, J.; Morris, M.C.; Ciaco, S.; Maskri, O.; Darlix, J.-L.; Mauffret, O.; Fossé, P.; Réal, E.; Mély, Y. Rationally Designed Peptides as Efficient Inhibitors of Nucleic Acid Chaperone Activity of HIV-1 Nucleocapsid Protein. Biochemistry, 2018, 57(30), 4562–4573. doi: 10.1021/acs.biochem.8b00527
  112. Kongkatigumjorn, N.; Smith, S.A.; Chen, M.Z.; Fang, K.; Yang, S.; Gillies, E.R.; Johnston, A.P.R.; Such, G.K. Controlling Endosomal Escape Using pH Responsive Nanoparticles with Tunable Disassembly. Applied Nano Materials, 2018, 1(7), 3164–3173. doi: 10.1021/acsanm.8b00338
  113. Ruan, S.; Qin, L.; Xiao, W.; Hu, C.; Zhou, Y.; Wang, R.; Sun, X.; Yu, W.; He, Q.; Gao, H. Acid-Responsive Transferrin Dissociation and GLUT Mediated Exocytosis for Increased Blood-Brain Barrier Transcytosis and Programmed Glioma Targeting Delivery. Advanced Functional Materials, 2018, 28(30), 1802227. doi: 10.1002/adfm.201802227
  114. He, S.; Li, C.; Zhang, Q.; Ding, J.; Liang, X.-J.; Chen, X.; Xiao, H.; Chen, X.; Zhou, D.; Huang, Y. Tailoring Platinum(IV) Amphiphiles for Self-Targeting All-in-One Assemblies as Precise Multimodal Theranostic Nanomedicine. ACS Nano, 2018, 12(7), 7272–7281. doi: 10.1021/acsnano.8b03476
  115. Wu, C.; Li, J.; Wang, W.; Hammond, P.T. Rationally Designed Polycationic Carriers for Potent Polymeric siRNA-Mediated Gene Silencing. ACS Nano, 2018, 12(7), 6504–6514. doi: 10.1021/acsnano.7b08777
  116. Bonnard, T.; Jayapadman, A.; Putri, J.A.; Cui, J.; Ju, Y.; Carmichael, C.; Angelovich, T.A.; Cody, S.H.; French, S.; Pascaud, K.; Pearce, H.A.; Jagdale, S.; Caruso, F.; Hagemeyer, C.E. Low-Fouling and Biodegradable Protein-Based Particles for Thrombus Imaging. ACS Nano, 2018, 12(7), 6988–6996. doi: 10.1021/acsnano.8b02588
  117. Surya, S.L.; Long, M.J.C.; Urul, D.A.; Zhao, Y.; Mercer, E.J.; EIsaid, I.M.; Evans, T.; Aye, Y. Cardiovascular Small Heat Shock Protein HSPB7 Is a Kinetically Privileged Reactive Electrophilic Species (RES) Sensor. ACS Chemical Biology, 2018, 13(7), 1824–1831. doi: 10.1021/acschembio.7b00925
  118. Owiti, N.; Wei, S.; Bhagwat, A.; Kim, N. Unscheduled DNA synthesis leads to elevated uracil residues at highly transcribed genomic loci in Saccharomyces cerevisiae. PLoS Genetics, 2018, 14(7), e1007516. doi: 10.1371/journal.pgen.1007516
  119. Guo, X.; Zou, C.-L.; Jung, H.; Gong, Z.; Bruch, A.; Jiang, L.; Tang, H.X. Efficient Generation of a Near-visible Frequency Comb via Cherenkov-like Radiation from a Kerr Microcomb. Physical Review Applied, 2018, 10(1), 014012. doi: 10.1103/PhysRevApplied.10.014012
  120. Stambaugh, A.; Parks, J.W.; Stott, M.A.; Meena, G.G.; Hawkins, A.R.; Schmidt, H. Optofluidic detection of Zika nucleic acid and protein biomarkers using multimode interference multiplexing. Biomedical Optics Express, 2018, 9(8), 3725–3730. doi: 10.1364/BOE.9.003725
  121. Deshmukh, R.; Biehs, S.-A.; Khwaja, E.; Galfsky, T.; Agarwal, G.S.; Menon, V.M. Long-range resonant energy transfer using optical topological transitions in metamaterials. ACS Photonics, 2018, 5(7), 2737–2741. doi: 10.1021/acsphotonics.8b00484
  122. Yang, J.; Jiang, Q.; He, L.; Zhan, P.; Liu, Q.; Liu, S.; Fu, M.; Liu, J.; Li, C.; Ding, B. Self-Assembled Double-Bundle DNA Tetrahedron for Efficient Antisense Delivery. ACS Applied Materials & Interfaces, 2018, 10(28), 23693–23699. doi: 10.1021/acsami.8b07889
  123. Nuhn, L.; Boli, E.; Massa, S.; Vandenberghe, I.; Movahedi, K.; Devreese, B.; Van Ginderachter, J.; De Geest, B.G. Targeting protumoral tumor-associated macrophages with nanobody-functionalized nanogels through SPAAC ligation. Bioconjugate Chemistry, 2018, 29(7), 2394–2405. doi: 10.1021/acs.bioconjchem.8b00319
  124. Men, Y.; Peng, S.; Yang, P.; Jiang, Q.; Zhang, Y.; Shen, B.; Dong, P.; Pang, Z.; Yang, W. Biodegradable Zwitterionic Nanogels with Long Circulation for Antitumor Drug Delivery. ACS Applied Materials & Interfaces, 2018, 10(28), 23509–23521. doi: 10.1021/acsami.8b03943
  125. Chung, S.W.; Choi, J.U.; Cho, Y.S.; Kim, H.R.; Won, T.H.; Dimitrion, P.; Jeon, O.-C.; Kim, S.W.; Kim, I.-S.; Kim, S.Y.; Byun, Y. Self-Triggered Apoptosis Enzyme Prodrug Therapy (STAEPT): Enhancing Targeted Therapies via Recurrent Bystander Killing Effect by Exploiting Caspase-Cleavable Linker. Advanced Science, 2018, 5(7), 1800368. doi: 10.1002/advs.201800368
  126. Hernandez-Segura, A.; Brandenburg, S.; Demaria, M. Induction and Validation of Cellular Senescence in Primary Human Cells. Journal of Visualized Experiments, 2018, 136, e57782. doi: 10.3791/57782
  127. Tabe, H.; Sukenobe, K.; Kondo, T.; Sakurai, A.; Maruo, M.; Shimauchi, A.; Hirano, M.; Uno, S.-N.; Kamiya, M.; Urano, Y.; Matsushita, M.; Fujiyoshi, S. Cryogenic Fluorescence Localization Microscopy of Spectrally Selected Individual FRET Pairs in a Water Matrix. The Journal of Physical Chemistry B, 2018, 122(27), 6906–6911. doi: 10.1021/acs.jpcb.8b03977
  128. Tamošiūnė, I.; Stanienė, G.; Haimi, P.; Stanys, V.; Rugienius, R.; Baniulis, D. Endophytic Bacillus and Pseudomonas spp. Modulate Apple Shoot Growth, Cellular Redox Balance, and Protein Expression Under in Vitro Conditions. Frontiers in Plant Science, 2018, 9, 889. doi: 10.3389/fpls.2018.00889
  129. Salinas, C.B.G.; Lu, T.T.-H.; Gabery, S.; Marstal, K.; Alanentalo, T.; Mercer, A.J.; Cornea, A.; Conradsen, K.; Hecksher-Sørensen, J.; Dahl, A.B.; Knudsen, L.B.; Secher, A. Integrated Brain Atlas for Unbiased Mapping of Nervous System Effects Following Liraglutide Treatment. Scientific Reports, 2018, 8, 10310. doi: 10.1038/s41598-018-28496-6
  130. Souchek, J.J.; Wojtynek, N.E.; Payne, W.M.; Holmes, M.B.; Dutta, S.; Qi, B.; Datta, K.; LaGrange, C.A.; Mohs, A.M. Hyaluronic acid formulation of near infrared fluorophores optimizes surgical imaging in a prostate tumor xenograft. Acta Biomaterialia, 2018, 75, 323–333. doi: 10.1016/j.actbio.2018.06.016
  131. Nunes, R.; Araújo, F.; Tavares, J.; Sarmento, B.; das Neves, J. Surface modification with polyethylene glycol enhances colorectal distribution and retention of nanoparticles. European Journal of Pharmaceutics and Biopharmaceutics, 2018, 130, 200–206. doi: 10.1016/j.ejpb.2018.06.029
  132. Liu, H.-J.; Luan, X.; Feng, H.-Y.; Dong, X.; Yang, S.-C.; Chen, Z.-J.; Cai, Q.-Y.; Lu, Q.; Zhang, Y.; Sun, P.; Zhao, M.; Chen, H.-Z.; Lovell, J.F.; Fang, C. Integrated Combination Treatment Using a "Smart" Chemotherapy and MicroRNA Delivery System Improves Outcomes in an Orthotopic Colorectal Cancer Mode. Advanced Functional Materials, 2018, 28(28), 1801118. doi: 10.1002/adfm.201801118
  133. Tang, H.; Zhang, J.; Tang, J.; Shen, Y.; Guo, W.; Zhou, M.; Wang, R.; Jiang, N.; Gan, Z.; Yu, Q. Tumor specific and renal excretable star-like tri-block polymer-doxorubicin conjugates for safe and efficient anticancer therapy. Biomacromolecules, 2018, 19(7), 2849–2862. doi: 10.1021/acs.biomac.8b00425
  134. Sarker, B.; Walter, C.; Pathak, A. Direct micropatterning of {ECM} proteins on functionalized polyacrylamide hydrogels shows geometric regulation of cell-cell junctions. ACS Biomaterials Science & Engineering, 2018, 4(7), 2340–2349. doi: 10.1021/acsbiomaterials.8b00331
  135. Cui, Z.; Wu, Y.; Mureev, S.; Alexandrov, K. Oligonucleotide-mediated tRNA sequestration enables one-pot sense codon reassignment in vitro. Nucleic Acids Research, 2018, 46(12), 6387–6400. doi: 10.1093/nar/gky365
  136. Xue, F.; Wang, Y.; Zhang, Q.; Han, S.; Zhang, F.; Jin, T.; Li, C.; Hu, H.; Zhang, J. Self-assembly of affinity-controlled nanoparticles via host-guest interactions for drug delivery. Nanoscale, 2018, 10(26), 12364–12377. doi: 10.1039/C8NR01518J
  137. Tovar-Herrera, O.E.; Rodríguez, M.; Olarte-Lozano, M.; Sampedro-Guerrero, J.A.; Guerrero, A.; Pinto-Cámara, R.; Alvarado-Affantranger, X.; Wood, C.D.; Moran-Mirabal, J.M.; Pastor, N.; Segovia, L.; Martínez-Anaya, C. Analysis of the Binding of Expansin Exl1, from Pectobacterium carotovorum, to Plant Xylem and Comparison to EXLX1 from Bacillus subtilis. ACS Omega, 2018, 3(6), 7008–7018. doi: 10.1021/acsomega.8b00406
  138. Buecheler, J.W.; Winzer, M.; Tonillo, J.; Weber, C.A.; Gieseler, H. Impact of Payload Hydrophobicity on Stability of Antibody-Drug-Conjugates. Molecular Pharmaceutics, 2018, 15(7), 2656–2664. doi: 10.1021/acs.molpharmaceut.8b00177
  139. Chen, J.; Zhou, J.; Gao, Z.; Li, X.; Wang, F.; Duan, X.; Li, G.; Joshi, B.; Kuick, R.D.; Appelman, H.D.; Wang, T. Multiplexed Targeting of Barrett's Neoplasia with a Heterobivalent Ligand: Imaging Study on Mouse Xenograft In Vivo and Human Specimens Ex Vivo. Journal of Medicinal Chemistry, 2018, 61(12), 5323–5331. doi: 10.1021/acs.jmedchem.8b00405
  140. Wang, B.; Chen, G.; Urabe, G.; Xie, R.; Wang, Y.; Shi, X.; Guo, L.-W.; Gong, S.; Kent, K.C. A paradigm of endothelium-protective and stent-free anti-restenotic therapy using biomimetic nanoclusters. Biomaterials, 2018, 178, 293–301. doi: 10.1016/j.biomaterials.2018.06.025
  141. Roberts, S.; Andreou, C.; Choi, C.; Donabedian, P.; Jayaraman, M.; Pratt, E.C.; Tang, J.; Pérez-Medina, C.; de la Cruz, M.J.; Mulder, W.J.M.; Grimm, J.; Kircher, M.; Reiner, T. Sonophore-enhanced nanoemulsions for optoacoustic imaging of cancer. Chemical Science, 2018, 9(25), 5646–5657. doi: 10.1039/C8SC01706A
  142. Moroz, P.; Jin, Z.; Sugiyama, Y.; Lara, D'A.; Razgoniaeva, N.; Yang, M.; Kholmicheva, N.; Khon, D.; Mattoussi, H.; Zamkov, M. The Competition of Charge and Energy Transfer Processes in Donor-Acceptor Fluorescence Pairs: Calibrating the Spectroscopic Ruler. ACS Nano, 2018, 12(6), 5657–5665. doi: 10.1021/acsnano.8b01451
  143. Patiño, T.; Feiner-Gracia, N.; Arqué, X.; Miguel-López, A.; Jannasch, A.; Stumpp, T.; Schäffer, E.; Albertazzi, L.; Sánchez, S. Influence of Enzyme Quantity and Distribution on the Self-Propulsion of Non-Janus Urease-Powered Micromotors. Journal of the American Chemical Society, 2018, 140(25), 7896–7903. doi: 10.1021/jacs.8b03460
  144. Blackman, L.D.; Varlas, S.; Arno, M.C.; Houston, Z.H.; Fletcher, N.L.; Thurecht, K.J.; Hasan, M.; Gibson, M.I.; O'Reilly, R.K. Confinement of Therapeutic Enzymes in Selectively Permeable Polymer Vesicles by Polymerization-Induced Self-Assembly (PISA) Reduces Antibody Binding and Proteolytic Susceptibility. Central Science, 2018, 4(6), 718–723. doi: 10.1021/acscentsci.8b00168
  145. Garcia, F.; Rippe, M.; Companhoni, M.V.; Stefanello, T.; Louage, B.; van Herck, S.; Sancey, L.; Coll, J.-L.; De Geest, B.; Nakamura, C.V.; Auzély-Velty, R. A versatile method for the selective core-crosslinking of hyaluronic acid-based nanogels via ketone-hydrazide chemistry: from chemical characterization to in vivo biodistribution. Biomaterials Science, 2018, 6(7), 1754–1763. doi: 10.1039/c8bm00396c
  146. Selnihhin, D.; Sparvath, S.M.; Preus, S.; Birkedal, V.; Andersen, E.S. Multi-Fluorophore DNA Origami Beacon as a Biosensing Platform. ACS Nano, 2018, 12(6), 5699–5708. doi: 10.1021/acsnano.8b01510
  147. Li, H.; Li, K.; Dai, Y.; Xu, X.; Cao, X.; Zeng, Q.; He, H.; Pang, L.; Liang, J.; Chen, X.; Zhan, Y. In vivo near infrared fluorescence imaging and dynamic quantification of pancreatic metastatic tumors using folic acid conjugated biodegradable mesoporous silica nanoparticles. Nanomedicine: Nanotechnology, Biology and Medicine, 2018, 14(6), 1867–1877. doi: 10.1016/j.nano.2018.04.018
  148. Liang, Y.; Huo, Q.; Lu, W.; Jiang, L.; Gao, W.; Xu, L.; Han, S.; Cao, J.; Zhang, T.; Sun, Y.; He, B. Fluorescence Resonance Energy Transfer Visualization of Molecular Delivery from Polymeric Micelles. Journal of Biomedical Nanotechnology, 2018, 14(7), 1308–1316. doi: 10.1166/jbn.2018.2585
  149. Yang, Y.; Chen, Q.; Li, S.; Ma, W.; Yao, G.; Ren, F.; Cai, Z.; Zhao, P.; Liao, G.; Xiong, J.; Yu, Z. iRGD-Mediated and Enzyme-Induced Precise Targeting and Retention of Gold Nanoparticles for the Enhanced Imaging and Treatment of Breast Cancer. Journal of Biomedical Nanotechnology, 2018, 14(8), 1396–1408. doi: 10.1166/jbn.2018.2592
  150. Gusliakova, O.; Atochina-Vasserman, E.N.; Sindeeva, O.; Sindeev, S.; Pinyaev, S.; Pyataev, N.; Revin, V.; Sukhorukov, G.B.; Gorin, D.; Gow, A.J. Use of Submicron Vaterite Particles Serves as an Effective Delivery Vehicle to the Respiratory Portion of the Lung. Frontiers in Pharmacology, 2018, 9, 559. doi: 10.3389/fphar.2018.00559
  151. Chambre, L.; Degirmenci, A.; Sanyal, R.; Sanyal, A. Multifunctional Nanogels as Theranostic Platforms: Exploiting Reversible and Non-reversible Linkages for Targeting, Imaging and Drug Delivery. Bioconjugate Chemistry, 2018, 29(6), 1885–1896. doi: 10.1021/acs.bioconjchem.8b00085
  152. Ashwanikumar, N.; Plaut, J.S.; Mostofian, B.; Patel, S.; Kwak, P.; Sun, C.; McPhail, K.; Zuckerman, D.M.; Esener, S.C.; Sahay, G. Supramolecular self assembly of nanodrill-like structures for intracellular delivery. Journal of Controlled Release, 2018, 282, 76–89. doi: 10.1016/j.jconrel.2018.02.041
  153. Li, H.; Zhang, Z.; Bao, X.; Xu, G.; Yao, P. Fatty acid and quaternary ammonium modified chitosan nanoparticles for insulin delivery. Colloids and Surfaces, B: Biointerfaces, 2018, 170, 136–143. doi: 10.1016/j.colsurfb.2018.05.063
  154. Tsikandelova, R.; Mladenov, P.; Planchon, S.; Kalenderova, S.; Praskova, M.; Mihaylova, Z.; Stanimirov, P.; Mitev, V.; Renaut, J.; Ishkitiev, N. Proteome response of dental pulp cells to exogenous FGF8. Journal of Proteomics, 2018, 183, 14–24. doi: 10.1016/j.jprot.2018.05.004
  155. Parayath, N.N.; Parikh, A.; Amiji, M.M. Repolarization of Tumor-Associated Macrophages in a Genetically Engineered Nonsmall Cell Lung Cancer Model by Intraperitoneal Administration of Hyaluronic Acid-Based Nanoparticles Encapsulating MicroRNA-125b. Nano Letters, 2018, 18(6), 3571–3579. doi: 10.1021/acs.nanolett.8b00689
  156. Rho, J.Y.; Brendel, J.C.; MacFarlane, L.R.; Mansfield, E.D.H.; Peltier, R.; Rogers, S.; Hartlieb, M.; Perrier, S. Probing the Dynamic Nature of Self-Assembling Cyclic Peptide–Polymer Nanotubes in Solution and in Mammalian Cells. Advanced Functional Materials, 2018, 28(24), 1704569. doi: 10.1002/adfm.201704569
  157. Chiang, Y.-T.; Lyu, S.-Y.; Wen, Y.-H.; Lo, C.-L. Preparation and Characterization of Electrostatically Crosslinked Polymer-Liposomes in Anticancer Therapy. International Journal of Molecular Sciences, 2018, 19(6), 1615. doi: 10.3390/ijms19061615
  158. Hu, H.; Wan, J.; Huang, X.; Tang, Y.; Xiao, C.; Xu, H.; Yang, X.; Li, Z. iRGD-decorated reduction-responsive nanoclusters for targeted drug delivery. Nanoscale, 2018, 10(22), 10514–10527. doi: 10.1039/c8nr02534g
  159. Liu, C.-H.; Nevozhay, D.; Schill, A.; Singh, M.; Das, S.; Nair, A.; Han, Z.; Aglyamov, S.; Larin, K.V.; Sokolov, K.V. Nanobomb optical coherence elastography. Optics Letters, 2018, 43(9), 2006–2009. doi: 10.1364/OL.43.002006
  160. Malhotra, M.; Sekar, T.V.; Ananta, J.S.; Devulapally, R.; Afjei, R.; Babikir, H.A.; Paulmurugan, R.; Massoud, T.F. Targeted nanoparticle delivery of therapeutic antisense microRNAs presensitizes glioblastoma cells to lower effective doses of temozolomide in vitro and in a mouse model. Oncotarget, 2018, 9(30), 21478–21494. doi: 10.18632/oncotarget.25135
  161. Siltanen, C.A.; Cole, R.H.; Poust, S.; Chao, L.; Tyerman, J.; Kaufmann-Malaga, B.; Ubersax, J.; Gartner, Z.J.; Abate, A.R. An Oil-Free Picodrop Bioassay Platform for Synthetic Biology. Scientific Reports, 2018, 8, 7913. doi: 10.1038/s41598-018-25577-4
  162. Porciani, D.; Cardwell, L.N.; Tawiah, K.d.; Alam, K.K.; Lange, M.J.; Daniels, M.A.; Burke, D.H. Modular cell-internalizing aptamer nanostructure enables targeted delivery of large functional RNAs in cancer cell lines. Nature Communications, 2018, 9(1), 2283. doi: 10.1038/s41467-018-04691-x
  163. Ganapathy, U.S.; Bai, L.; Wei, L.; Eckartt, K.A.; Lett, C.M.; Previti, M.L.; Carrico, I.S.; Seeliger, J.C. Compartment-Specific Labeling of Bacterial Periplasmic Proteins by Peroxidase-Mediated Biotinylation. ACS Infectious Diseases, 2018, 4(6), 918–925. doi: 10.1021/acsinfecdis.8b00044
  164. Balke, J.; Volz, P.; Neumann, F.; Brodwolf, R.; Wolf, A.; Pischon, H.; Radbruch, M.; Mundhenk, L.; Gruber, A.D.; Ma, N.; Alexiev, U. Visualizing Oxidative Cellular Stress Induced by Nanoparticles in the Subcytotoxic Range Using Fluorescence Lifetime Imaging. Small, 2018, 14(23), 1800310. doi: 10.1002/smll.201800310
  165. Zemella, A.; Thoring, L.; Hoffmeister, C.; Šamalíková, M.; Ehren, P.; Wüstenhagen, D.A.; Kubick, S. Cell-free protein synthesis as a novel tool for directed glycoengineering of active erythropoietin. Scientific Reports, 2018, 8, 8514. doi: 10.1038/s41598-018-26936-x
  166. Tahara, H.; Takabe, K.; Sasaki, Y.; Kasuga, K.; Kawamoto, A.; Koizumi, N.; Nakamura, S. The mechanism of two-phase motility in the spirochete Leptospira: Swimming and crawling. Science Advances, 2018, 4(5), eaar7975. doi: 10.1126/sciadv.aar7975
  167. Semkina, A.S.; Abakumov, M.A.; Skorikov, A.S.; Abakumova, T.O.; Melnikov, P.A.; Grinenko, N.F.; Cherepanov, S.A.; Vishnevskiy, D.A.; Naumenko, V.A.; Ionova, K.P.; Majouga, A.G.; Chekhonin, V.P. Multimodal doxorubicin loaded magnetic nanoparticles for {VEGF} targeted theranostics of breast cancer. Nanomedicine: Nanotechnology, Biology and Medicine, 2018, 14(5), 1733–1742. doi: 10.1016/j.nano.2018.04.019
  168. Cun, X.; Li, M.; Wang, S.; Wang, Y.; Wang, J.; Lu, Z.; Yang, R.; Tang, X.; Zhang, Z.; He, Q. A size switchable nanoplatform for targeting the tumor microenvironment and deep tumor penetration. Nanoscale, 2018, 10(21), 9935–9948. doi: 10.1039/c8nr00640g
  169. Kao, C.-W.; Wu, P.-T.; Liao, M.-Y.; Chung, I.-J.; Yang, K.-C.; Tseng, W.-Y.I. Yu, J. Magnetic Nanoparticles Conjugated with Peptides Derived from Monocyte Chemoattractant Protein-1 as a Tool for Targeting Atherosclerosis. Pharmaceutics, 2018, 10(2), 62. doi: 10.3390/pharmaceutics10020062
  170. Shi, F.; Li, M.; Wang, J.; Wu, D.; Pan, M.; Guo, M.; Dou, J. Induction of multiple myeloma cancer stem cell apoptosis using conjugated anti-ABCG2 antibody with epirubicin-loaded microbubbles. Stem Cell Research & Therapy, 2018, 9, 144. doi: 10.1186/s13287-018-0885-2
  171. Shih, T.-Y.; Blacklow, S.O.; Li, A.W.; Freedman, B.R.; Bencherif, S.; Koshy, S.T.; Darnell, M.C.; Mooney, D.J. Injectable, Tough Alginate Cryogels as Cancer Vaccines. Advanced Healthcare Materials, 2018, 7(10), 1701469. doi: 10.1002/adhm.201701469
  172. Robinson, K.J.; Huynh, G.T.; Kouskousis, B.; Fletcher, N.L.; Houston, Z.H.; Thurecht, K.J.; Corrie, S.R. Modified organosilica core-shell nanoparticles for stable pH sensing in biological solutions. ACS Sensors, 2018, 3(5), 967–975. doi: 10.1021/acssensors.8b00034
  173. Mardirossian, M.; Pérébaskine, N.; Benincasa, M.; Gambato, S.; Hofmann, S.; Huter, P.; Müller, C.; Hilpert, K.; Innis, C.A.; Tossi, A.; Wilson, D.N. The Dolphin Proline-Rich Antimicrobial Peptide Tur1A Inhibits Protein Synthesis by Targeting the Bacterial Ribosome. Cell Chemical Biology, 2018, 25(5), 530–539.e7. doi: 10.1016/j.chembiol.2018.02.004
  174. Volkov, I.L.; Lindén, M.; Aguirre Rivera, J.; Ieong, K.-W.; Metelev, M.; Elf, J.; Johansson, M. tRNA tracking for direct measurements of protein synthesis kinetics in live cells. Nature Chemical Biology, 2018, 14(6), 618–626. doi: 10.1038/s41589-018-0063-y
  175. Akentieva, N.P.; Shushanov, S.S. Visualization of Ovarian Cancer Cells with Peptide VEGEGEEGEEY. Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology, 2018, 12(2), 189–198. doi: 10.1134/s1990747818020022
  176. Torres, O.B.; Duval, A.J.; Sulima, A.; Antoline, J.F.G.; Jacobson, A.E.; Rice, K.C.; Alving, C.R.; Matyas, G.R. A rapid solution-based method for determining the affinity of heroin hapten-induced antibodies to heroin, its metabolites, and other opioids. Analytical and Bioanalytical Chemistry, 2018, 410(16), 3885–3903. doi: 10.1007/s00216-018-1060-4
  177. Chen, C.C.; Stark, M.; Baikoghli, M.; Cheng, R.H. Surface Functionalization of Hepatitis E Virus Nanoparticles Using Chemical Conjugation Methods. Journal of Visualized Experiments, 2018, 135, e57020. doi: 10.3791/57020
  178. Wong, S.Z.H.; Scott, E.P.; Mu, W.; Guo, X.; Borgenheimer, E.; Freeman, M.; Ming, G.-L.; Wu, Q.-F.; Song, H.; Nakagawa, Y. In vivo clonal analysis reveals spatiotemporal regulation of thalamic nucleogenesis. PLoS Biology, 2018, 16, e2005211. doi: 10.1371/journal.pbio.2005211
  179. Kidwell, C.U.; Su, C.-Y.; Hibi, M.; Moens, C.B. Multiple zebrafish atoh1 genes specify a diversity of neuronal types in the zebrafish cerebellum. Developmental Biology, 2018, 438(1), 44–56. doi: 10.1016/j.ydbio.2018.03.004
  180. Larsen, K.P.; Mathiharan, Y.K.; Kappel, K.; Coey, A.T.; Chen, D.-H.; Barrero, D.; Madigan, L.; Puglisi, J.D.; Skiniotis, G.; Puglisi, E.V. Architecture of an HIV-1 reverse transcriptase initiation complex. Nature, 2018, 557, 118–122. doi: 10.1038/s41586-018-0055-9
  181. Bhatnagar, S.; Verma, K.D.; Hu, Y.; Khera, E.; Priluck, A.; Smith, D.E.; Thurber, G.M. Oral Administration and Detection of a Near-Infrared Molecular Imaging Agent in an Orthotopic Mouse Model for Breast Cancer Screening. Molecular Pharmaceutics, 2018, 15(5), 1746–1754. doi: 10.1021/acs.molpharmaceut.7b00994
  182. Peng, S.; Wang, W.; Chen, C. Surface Transient Binding Based Fluorescence Correlation Spectroscopy (STB-FCS), a Simple and Easy-to-Implement Method to Extend the Upper Limit of Time Window to Seconds. The Journal of Physical Chemistry B, 2018, 122(18), 4844–4850. doi: 10.1021/acs.jpcb.8b03476
  183. Wang, H.; Dai, T.; Li, S.; Zhou, S.; Yuan, X.; You, J.; Wang, C.; Mukwaya, V.; Zhou, G.; Liu, G.; Wei, X.; Dou, H. Scalable and cleavable polysaccharide nanocarriers for the delivery of chemotherapy drugs. Acta Biomaterialia, 2018, 72, 206–216. doi: 10.1016/j.actbio.2018.03.024
  184. Li, L.; Wang, C.; Huang, Q.; Xiao, J.; Zhang, Q.; Cheng, Y. A Degradable Hydrogel formed by Dendrimer-encapsulated Platinum Nanoparticle and Oxidized Dextran for Repeated Photothermal Cancer Therapy. Journal of Materials Chemistry B, 2018, 6(16), 2474–2480. doi: 10.1039/C8TB00091C
  185. Gupta, S.; M-Redmond, T; Meng, F.; Tidball, A.; Akil, H.; Watson, S.; Parent, J.M.; Uhler, M.; others. Fibroblast Growth Factor 2 Regulates Activity and Gene Expression of Human Postmitotic Excitatory Neuron. Journal of Neurochemistry, 2018, 145(3), 188–203. doi: 10.1111/jnc.14255
  186. Lee, K.; Zhang, L.; Yi, Y.; Wang, X.; Yu, Y. Rupture of Lipid Membranes Induced by Amphiphilic Janus Nanoparticles. ACS Nano, 2018, 12(4), 3646–3657. doi: 10.1021/acsnano.8b00759
  187. Lyu, Z.; Kang, L.; Buuh, Z.Y.; Jiang, D.; McGuth, J.C.; Du, J.; Wissler, H.L.; Cai, W.; Wang, R.E. A Switchable Site-Specific Antibody Conjugate. ACS Chemical Biology, 2018, 13(4), 958–964. doi: 10.1021/acschembio.8b00107
  188. Li, L.; Yang, J.; Wang, J.; Kopeček, J. Amplification of CD20 Cross-Linking in Rituximab-Resistant B-Lymphoma Cells Enhances Apoptosis Induction by Drug-Free Macromolecular Therapeutics. ACS Nano, 2018, 12(4), 3658–3670. doi: 10.1021/acsnano.8b00797
  189. Su, H.; Liu, Z.; Liu, Y.; Ma, V.P.-Y.; Blanchard, A.; Zhao, J.; Galior, K.; Dyer, R.B.; Salaita, K. Light-Responsive Polymer Particles as Force Clamps for the Mechanical Unfolding of Target Molecules. Nano Letters, 2018, 18(4), 2630–2636. doi: 10.1021/acs.nanolett.8b00459
  190. Sobotzki, N.; Schafroth, M.A.; Rudnicka, A.; Koetemann, A.; Marty, F.; Goetze, S.; Yamauchi, Y.; Carreira, E.M.; Wollscheid, B. HATRIC-based identification of receptors for orphan ligands. Nature Communications, 2018, 9, 1519. doi: 10.1038/s41467-018-03936-z
  191. Mietlicki-Baase, E.G.; Liberini, C.G.; Workinger, J.L.; Bonaccorso, R.L.; Borner, T.; Reiner, D.J.; Koch-Laskowski, K.; McGrath, L.E.; Lhamo, R.; Stein, L.M.; De Jonghe, B.C.; Holz, G.G.; Roth, C.L.; Doyle, R.P.; Hayes, M.R. A Vitamin B12 Conjugate of Exendin-4 Improves Glucose Tolerance Without Associated Nausea or Hypophagia in Rodents. Diabetes, Obesity & Metabolism, 2018, 20(5), 1223–1234. doi: 10.1111/dom.13222
  192. Gulati, N.M.; Pitek, A.S.; Czapar, A.E.; Stewart, P.L.; Steinmetz, N.F. The in vivo fates of plant viral nanoparticles camouflaged using self-proteins: overcoming immune recognition. Journal of Materials Chemistry B, 2018, 6(15), 2204–2216. doi: 10.1039/C7TB03106H
  193. Wojcik, F.; Dann, G.P.; Beh, L.Y.; Debelouchina, G.T.; Hofmann, R.; Muir, T.W. Functional crosstalk between histone H2B ubiquitylation and H2A modifications and variants. Nature Communications, 2018, 9, 1394. doi: 10.1038/s41467-018-03895-5
  194. Stadler, D.; Siribbal, S.M.; Gessner, I.; Öz, S.; Ilyas, S.; Mathur, S. Asymmetric attachment and functionalization of plasmonic nanoparticles on ceramic interfaces. Journal of Nanostructure in Chemistry, 2018, 8(1), 33–44. doi: 10.1007/s40097-018-0252-y
  195. He, H.; Chen, Y.; Li, Y.; Song, Z.; Zhong, Y.; Zhu, R.; Cheng, J.; Yin, L. Effective and Selective Anti-Cancer Protein Delivery via All-Functions-in-One Nanocarriers Coupled with Visible Light-Responsive, Reversible Protein Engineering. Advanced Functional Materials, 2018, 28(14), 1706710. doi: 10.1002/adfm.201706710
  196. Gadkari, V.V.; Harvey, S.R.; Raper, A.T.; Chu, W.-T.; Wang, J.; Wysocki, V.H.; Suo, Z. Investigation of sliding DNA clamp dynamics by single-molecule fluorescence, mass spectrometry and structure-based modeling. Nucleic Acids Research, 2018, 46(6), 3103–3118. doi: 10.1093/nar/gky125
  197. Huang, D.; Chen, Y.-S.; Green, C.R.; Rupenthal, I.D. Hyaluronic acid coated albumin nanoparticles for targeted peptide delivery in the treatment of retinal ischaemia. Biomaterials, 2018, 168, 10–23. doi: 10.1016/j.biomaterials.2018.03.034
  198. Nemmara, V.J.; Subramanian, V.; Muth, A.; Mondal, S.; Salinger, A.J.; Maurais, A.J.; Tilvawala, R.; Weerapana, E.; Thompson, P.R. The Development of Benzimidazole-Based Clickable Probes for the Efficient Labeling of Cellular Protein Arginine Deiminases (PADs). ACS Chemical Biology, 2018, 13(3), 712–722. doi: 10.1021/acschembio.7b00957
  199. Kim, H.-Y.; Wang, X.; Kang, R.; Tang, D.; Boone, B.A.; Zeh, H.J.; Lotze, M.T.; Edwards, W.B. RAGE-specific single chain Fv for PET imaging of pancreatic cancer. PLoS One, 2018, 13(3), e0192821. doi: 10.1371/journal.pone.0192821
  200. Gaspar, I.; Hövelmann, F.; Chamiolo, J.; Ephrussi, A.; Seitz, O. Quantitative mRNA Imaging with Dual Channel qFIT Probes to Monitor Distribution and Degree of Hybridization. ACS Chemical Biology, 2018, 13(3), 742–749. doi: 10.1021/acschembio.7b01007
  201. Zhang, X.; He, F.; Xiang, K.; Zhang, J.; Xu, M.; Long, P.; Su, H.; Gan, Z.; Yu, Q. CD44-targeted Facile Enzymatic Activatable Chitosan Nanoparticles for Efficient Antitumor Therapy and Reversal of Multidrug Resistance. Biomacromolecules, 2018, 19(3), 883–895. doi: 10.1021/acs.biomac.7b01676
  202. Lee, A.; Kim, S.H.; Lee, H.; Kim, B.; Kim, Y.S.; Key, J. Visualization of MMP-2 Activity Using Dual-Probe Nanoparticles to Detect Potential Metastatic Cancer Cells. Nanomaterials, 2018, 8(2), 119. doi: 10.3390/nano8020119
  203. Maudens, P.; Seemayer, C.A.; Thauvin, C.; Gabay, C.; Jordan, O.; Allémann, E. Nanocrystal-Polymer Particles: Extended Delivery Carriers for Osteoarthritis Treatment. Small, 2018, 14(8), 1703108. doi: 10.1002/smll.201703108
  204. Cai, H.; Wang, X.; Zhang, H.; Sun, L.; Pan, D.; Gong, Q.; Gu, Z.; Luo, K. Enzyme-sensitive biodegradable and multifunctional polymeric conjugate as theranostic nanomedicine. Applied Materials Today, 2018, 11, 207–218. doi: 10.1016/j.apmt.2018.02.003
  205. Yang, W.; Cao, Y.; Zhang, Z.; Du, F.; Shi, Y.; Li, X.; Zhang, Q. Targeted delivery of FGF2 to subchondral bone enhanced the repair of articular cartilage defect. Acta Biomaterialia, 2018, 69, 170–182. doi: 10.1016/j.actbio.2018.01.039
  206. Raper, A.T.; Stephenson, A.A.; Suo, Z. Functional Insights Revealed by the Kinetic Mechanism of CRISPR/Cas9. Journal of the American Chemical Society, 2018, 140(8), 2971–2984. doi: 10.1021/jacs.7b13047
  207. Liu, Z.; Wang, S.; Li, W.; Tian, Y. Bioimaging and Biosensing of Ferrous Ion in Neurons and HepG2 Cells Upon Oxidative Stress. Analytical Chemistry, 2018, 90(4), 2816–2825. doi: 10.1021/acs.analchem.7b04934
  208. Murata, H.; Carmali, S.; Baker, S.L.; Matyjaszewski, K.; Russell, A.J. Solid-phase synthesis of protein-polymers on reversible immobilization supports. Nature Communications, 2018, 9, 845. doi: 10.1038/s41467-018-03153-8
  209. Jani, S.; Jackson, A.; Davies-Sala, C.; Chiem, K.; Soler-Bistué, A.; Zorreguieta, A.; Tolmasky, M.E. Assessment of External Guide Sequences' (EGS) Efficiency as Inducers of RNase P-Mediated Cleavage of mRNA Target Molecules. Methods in Molecular Biology, 2018, 1737, 89–98. doi: 10.1007/978-1-4939-7634-8_6
  210. Alric, C.; Hervé-Aubert, K.; Aubrey, N.; Melouk, S.; Lajoie, L.; Même, W.; Même, S.; Courbebaisse, Y.; Ignatova, A.A.; Feofanov, A.V.; Chourpa, I.; Allard-Vannier, E. Targeting HER2-breast tumors with scFv-decorated bimodal nanoprobes. Journal of Nanobiotechnology, 2018, 16, 18. doi: 10.1186/s12951-018-0341-6
  211. Poreba, M.; Rut, W.; Vizovisek, M.; Groborz, K.; Kasperkiewicz, P.; Finlay, D.; Vuori, K.; Turk, D.; Turk, B.; Salvesen, G.; Drag, M. Selective imaging of human cathepsin L in breast cancer by fluorescent activity-based probes. Chemical Science, 2018, 9(8), 2113–2129. doi: 10.1039/C7SC04303A
  212. Wang, Y.; Qiao, S.-L.; Wang, H. Facile Synthesis of Peptide-Crosslinked Nanogels for Tumor Metastasis Inhibition. ACS Applied Nano Materials, 2018, 1(2), 785–792. doi: 10.1021/acsanm.7b00203
  213. Raghupathi, K.; Skinner, M.; Chang, G.; Crawley, C.; Yoshida-Moriguchi, T.; Pipenhagen, P.; Zhu, Y.; Avila, L.Z.; Miller, R.J.; Dhal, P.K. Hyaluronic Acid Microgels as Intracellular Endosomolysis Reagents. ACS Biomaterials Science & Engineering, 2018, 4(2), 558–565. doi: 10.1021/acsbiomaterials.7b00966
  214. Xie, H.; Shao, J.; Ma, Y.; Wang, J.; Huang, H.; Yang, N.; Wang, H.; Ruan, C.; Luo, Y.; Wang, Q.-Q.; Chuc, P.K.; Yu, X.-F. Biodegradable near-infrared-photoresponsive shape memory implants based on black phosphorus nanofillers. Biomaterials, 2018, 164, 11–21. doi: 10.1016/j.biomaterials.2018.02.040
  215. Cheng, T.; Zhang, Y.; Liu, J.; Ding, Y.; Ou, H.; Huang, F.; An, Y.; Liu, Y.; Liu, J.; Shi, L. Ligand-Switchable Micellar Nanocarriers for Prolonging Circulation Time and Enhancing Targeting Efficiency. ACS Applied Materials & Interfaces, 2018, 10(6), 5296–5304. doi: 10.1021/acsami.7b18137
  216. Long, M.J.C.; Urul, D.A.; Chawla, S.; Lin, H.-Y.; Zhao, Y.; Haegele, J.A.; Wang, Y.; Aye, Y. Precision Electrophile Tagging in Caenorhabditis elegans. Biochemistry, 2018, 57(2), 216–220. doi: 10.1021/acs.biochem.7b00642
  217. Jeschke, A.; Haas, A. Sequential actions of phosphatidylinositol phosphates regulate phagosome-lysosome fusion. Molecular Biology of the Cell, 2018, 29(4), 452–465. doi: 10.1091/mbc.E17-07-0464
  218. Zhao, Y.; Zhang, W.; Li, C. Optimization of the conical mirror design based on Monte Carlo simulations for fluorescence molecular tomography. SPIE Proceedings: Multimodal Biomedical Imaging XIII, 2018, 10487, 104870M. doi: 10.1117/12.2290665
  219. Zhao, M.; Steffen, F.D.; and Börner, R.; Schaffer, M.F.; Sigel, R.K.O.; Freisinger, E. Site-specific dual-color labeling of long RNAs for single-molecule spectroscopy. Nucleic Acids Research, 2018, 46(3), e13. doi: 10.1093/nar/gkx1100
  220. Andrianova, M.; Komarova, N.; Grudtsov, V.; Kuznetsov, E.; Kuznetsov, A. Amplified Detection of the Aptamer-Vanillin Complex with the Use of Bsm DNA Polymerase. Sensors, 2018, 18, 49. doi: 10.3390/s18010049
  221. Ghai, A.; Maji, D.; Rettig, M.; Chanswangphuwana, C.; DiPersio, J.; Akers, W.; Achilefu, S.; Dehdashti, F.; Vij, R.; Shokeen, M. Preclinical development of CD38-targeted [89Zr]Zr-DFO-daratumumab for imaging multiple myeloma. Journal of Nuclear Medicine, 2018, 59(2), 216–222. doi: 10.2967/jnumed.117.196063
  222. Tal, N.; Rudnick-Glick, S.; Grinberg, I.; Natan, M.; Banin, E.; Margel, S. Engineering of a New Bisphosphonate Monomer and Nanoparticles of Narrow Size Distribution for Antibacterial Applications. ACS Omega, 2018, 3(2), 1458–1469. doi: 10.1021/acsomega.7b01686
  223. Lam, R.; Gondin, A.B.; Canals, M.; Kellam, B.; Briddon, S.J.; Graham, B.; Scammells, P.J. Fluorescently Labelled Morphine Derivatives for Bioimaging Studies. Journal of Medicinal Chemistry, 2018, 61(3), 1316–1329. doi: 10.1021/acs.jmedchem.7b01811
  224. Jun, D.; Minic, Z.; Bhat, S.V.; Vanderlinde, E.M.; Yost, C.K.; Babu, M.; Dahms, T.E.S. Metabolic Adaptation of a C-Terminal Protease A-Deficient Rhizobium leguminosarum in Response to Loss of Nutrient Transport. Frontiers in Microbiology, 2018, 8, 2617. doi: 10.3389/fmicb.2017.02617
  225. He, H.; Markoutsa, E.; Li, J.; Xu, P. Repurposing Disulfiram for Cancer Therapy via Targeted Nanotechnology through Enhanced Tumor Mass Penetration and Disassembly. Acta Biomaterialia, 2018, 68, 113–124. doi: 10.1016/j.actbio.2017.12.023
  226. Rambarran, T.; Gonzaga, F.; Fatona, A.; Coulson, M.; Saem, S.; Moran-Mirabal, J.; Brook, M.A. Bonding and in-channel microfluidic functionalization using the huisgen cyclization. ournal of Polymer Science Part A: Polymer Chemistry, 2018, 56(6), 589–597. doi: 10.1002/pola.28930
  227. Sallada, N.D.; Dunn, K.J.; Berger, B.W. A structural and functional role for disulfide bonds in a class II hydrophobin. Biochemistry, 2018, 57(5), 645–653. doi: 10.1021/acs.biochem.7b01166
  228. Condon, S.G.F.; Mahbuba, D.-A.; Armstrong, C.R.; Díaz-Vázquez, G.; Craven, S.J.; LaPointe, L.M.; Khadria, A.S.; Chadda, R.; Crooks, J.A.; Rangarajan, N.; Weibel, D.B.; Hoskins, A.A.; Robertson, J.L.; Cui, Q.; Senes, A. The FtsLB sub-complex of the bacterial divisome is tetramer with an uninterrupted FtsL helix linking the transmembrane and periplasmic regions. Journal of Biological Chemistry, 2018, 293(5), 1623–1641. doi: 10.1074/jbc.RA117.000426
  229. Grube, L.; Dellen, R.; Kruse, F.; Schwender, H.; Stuehler, K.; Poschmann, G. Mining the secretome of C2C12 muscle cells: Data dependent experimental approach to analyze protein secretion using label-free quantification and peptide based analysis. Journal of Proteome Research, 2018, 17(2), 879–890. doi: 10.1021/acs.jproteome.7b00684
  230. Kim, H.; Shin, K.; Park, O.K.; Choi, D.; Kim, H.D.; Baik, S.; Lee, S.H.; Kwon, S.-H.; Yarema, K.J.; Hong, J.; Hyeon, T.; Hwang, N.S. General and Facile Coating of Single Cells via Mild Reduction. Journal of the American Chemical Society, 2018, 140(4), 1199–1202. doi: 10.1021/jacs.7b08440
  231. Cho, U.; Riordan, D.P.; Ciepla, P.; Kocherlakota, K.S.; Chen, J.K.; Harbury, P.B. Ultrasensitive optical imaging with lanthanide lumiphores. Nature Chemical Biology, 2018, 14(1), 15–21. doi: 10.1038/nchembio.2513
  232. Jasinski, D.L.; Yin, H.; Li, Z.; Guo, P. The Hydrophobic Effect from Conjugated Chemicals or Drugs on in Vivo Biodistribution of RNA Nanoparticles. Human Gene Therapy, 2018, 29(1), 77–86. doi: 10.1089/hum.2017.054
  233. Li, L.; Yang, J.; Wang, J.; Kopeček, J. Drug-Free Macromolecular Therapeutics Induce Apoptosis via Calcium Influx and Mitochondrial Signaling Pathway. Macromolecular Bioscience, 2018, 1, 1700196. doi: 10.1002/mabi.201700196
  234. Park, J.; Hwang, S.R.; Choi, J.U.; Alam, F.; Byun, Y. Self-assembled nanocomplex of PEGylated protamine and heparin–suramin conjugate for accumulation at the tumor site. International Journal of Pharmaceutics, 2018, 535(1–2), 38–46. doi: 10.1016/j.ijpharm.2017.10.055
  235. Hori, A.; Kurata, S.; Kuraishi, T. Unexpected role of the IMD pathway in Drosophila gut defense against Staphylococcus aureus. Biochemical and Biophysical Research Communications, 2018, 495(1), 395–400. doi: 10.1016/j.bbrc.2017.11.004
  236. Penn, C.; Yang, K.; Zong, H.; Lim, J.-Y.; Cole, A.; Yang, D.; Baker, J.; Goonewardena, S.N.; Buckanovich, R.J. Therapeutic Impact of Nanoparticle Therapy Targeting Tumor Associated Macrophages. Molecular Cancer Therapeutics, 2018, 17(1), 96–106. doi: 10.1158/1535-7163.MCT-17-0688
  237. Maudens, P.; Meyer, S.; Seemayer, C.A.; Jordan, O.; Allémann, E. Self-assembled thermoresponsive nanostructures of hyaluronic acid conjugates for osteoarthritis therapy. Nanoscale, 2018, 10(4), 1845–1854. doi: 10.1039/C7NR07614B
  238. Jaworski, E.; Routh, A. ClickSeq: Replacing Fragmentation and Enzymatic Ligation with Click-Chemistry to Prevent Sequence Chimeras. Methods in Molecular Biology, 2018, 1712, 71–85. doi: 10.1007/978-1-4939-7514-3_6
  239. Wijnands, S.P.W.; Engelen, W.; Lafleur, R.P.M.; Meijer, E.W.; Merkx, M. Controlling protein activity by dynamic recruitment on a supramolecular polymer platform. Nature Communications, 2018, 9, 65. doi: 10.1038/s41467-017-02559-0
  240. Locke, L.W.; Kothandaraman, S.; Tweedle, M.; Chaney, S.; Wozniak, D.; Schlesinger, L.S. Use of a leukocyte-targeted peptide probe as a potential tracer for imaging the tuberculosis granuloma. Tuberculosis, 2018, 108, 201–210. doi: 10.1016/j.tube.2018.01.001
  241. Agrawalla, B.K.; Wang, T.; Riegger, A.; Domogalla, M.P.; Steinbrink, K.; Dörfler, T.; Chen, X.; Boldt, F.; Lamla, M.; Michaelis, J.; Kuan, S.L.; Weil, T. Chemoselective Dual and Triple Labelling of Native and Recombinant Proteins. Bioconjugate Chemistry, 2018, 29(1), 29–34. doi: 10.1021/acs.bioconjchem.7b00675
  242. Yao, L.; Li, Q.; Guan, Y.; Zhu, X.X.; Zhang, Y. Tetrahedral, Octahedral, and Triangular Dipyramidal Microgel Clusters with Thermosensitivity Fabricated from Binary Colloidal Crystals Template and Thiol–Ene Reaction. ACS Macro Letters, 2018, 7, 80–84. doi: 10.1021/acsmacrolett.7b00935
  243. Wu, Y.; Zhang, L.; Cui, C.; Cansiz, S.; Liang, H.; Wu, C.; Teng, I.-T.; Chen, W.; Liu, Y.; Hou, W.; Zhang, X.; Tan, W. Enhanced Targeted Gene Transduction: AAV2 Vectors Conjugated to Multiple Aptamers via Reducible Disulfide Linkages. Journal of the American Chemical Society, 2018, 140(1), 2–5. doi: 10.1021/jacs.7b08518
  244. Miragoli, M.; Ceriotti, P.; Iafisco, M.; Vacchiano, M.; Salvarani, N.; Alogna, A.; Carullo, P.; Ramirez-Rodríguez, G.B.; Patrício, T.; Esposti, L.D.; Rossi, F.; Ravanetti, F.; Pinelli, S.; Alinovi, R.; Erreni, M.; Rossi, S.; Condorelli, G.; Post, H.; Tampieri, A.; Catalucci, D. Inhalation of peptide-loaded nanoparticles improves heart failure. Science Translational Medicine, 2018, 10(424), eaan6205. doi: 10.1126/scitranslmed.aan6205
  245. Mansour, V.J.; Coorssen, J.R. Quantitative Gel Electrophoresis. In: de Almeida, A.; Eckersall, D.; Miller, I. (eds) Proteomics in Domestic Animals: from Farm to Systems Biology. Springer, Cham, 2018, pp 17–35. doi: 10.1007/978-3-319-69682-9_3
  246. Ou, H.; Cheng, T.; Zhang, Y.; Liu, J.; Ding, Y.; Zhen, J.; Shen, W.; Xu, Y.; Yang, W.; Niu, P.; Liu, J.; An, Y.; Liu, Y.; Shi, L. Surface-adaptive Zwitterionic Nanoparticles for Prolonged Blood Circulation Time and Enhanced Cellular Uptake in Tumor Cells. Acta Biomaterialia, 2018, 65, 339–348. doi: 10.1016/j.actbio.2017.10.034
  247. Giulbudagian, M.; Yealland, G.; Hönzke, S.; Edlich, A.; Geisendörfer, B.; Kleuser, B.; Hedtrich, S.; Calderón, M. Breaking the Barrier-Potent Anti-Inflammatory Activity following Efficient Topical Delivery of Etanercept using Thermoresponsive Nanogels. Theranostics, 2018, 8(2), 450–463. doi: 10.7150/thno.21668
  248. Ashcheulova, D.O.; Efimova, L.V.; Lushchyk, A.Y.; Yantsevich, A.V.; Baikov, A.N.; Pershina, A.G. Production of the recombinant antimicrobial peptide UBI18–35 in Escherichia coli. Protein Expression and Purification, 2018, 143, 38–44. doi: 10.1016/j.pep.2017.10.011
  249. Sato, S.-I.; Yatsuzuka, K.; Katsuda, Y.; Uesugi, M. Method for Imaging Live-Cell RNA Using an RNA Aptamer and a Fluorescent Probe. Methods in Molecular Biology, 2018, 1649, 305–318. doi: 10.1007/978-1-4939-7213-5_20
  250. Tian, T.; Zhang, H.-X.; He, C.-P.; Fan, S.; Zhu, Y.-L.; Qi, C.; Huang, N.-P.; Xiao, Z.-D.; Lu, Z.-H.; Tannous, B.A.; Gao, J. Surface functionalized exosomes as targeted drug delivery vehicles for cerebral ischemia therapy. Biomaterials, 2018, 150, 137–149. doi: 10.1016/j.biomaterials.2017.10.012
  251. Cioloboc, D.; Kennedy, C.; Boice, E.N.; Clark, E.R.; Kurtz, D.M. A Trojan Horse for Light-Triggered Bifurcated Production of Singlet Oxygen and Fenton-Reactive Iron Within Cancer Cells. Biomacromolecules, 2018, 19(1), 178–187. doi: 10.1021/acs.biomac.7b01433
  252. Das, S.; Haedicke, K.; Grimm, J. Cerenkov-activated sticky tag for in vivo fluorescence imaging. Journal of Nuclear Medicine, 2018, 59(1), 58–65. doi: 10.2967/jnumed.117.198549
  253. Kuznetsov, A.; Komarova, N.; Andrianova, M.; Grudtsov, V.; Kuznetsov, E. Aptamer based vanillin sensor using an ion-sensitive field-effect transistor. Microchimica Acta, 2018, 185(1), 3. doi: 10.1007/s00604-017-2586-4
  254. Newman, M.R.; Russell, S.G.; Schmitt, C.S.; Marozas, I.A.; Sheu, T.-J.; Puzas, J.E.; Benoit, D.S.W. Multivalent Presentation of Peptide Targeting Groups Alters Polymer Biodistribution to Target Tissues. Biomacromolecules, 2018, 19(1), 71–84. doi: 10.1021/acs.biomac.7b01193
  255. Timin, A.S.; Muslimov, A.R.; Lepik, K.V.; Epifanovskaya, O.S:; Shakirova, A.I.; Mock, U.; Riecken, K.; Okilova, M.V.; Sergeev, V.S.; Afanasyev, B.V.; Fehse, B.; Sukhorukov, G.B. Efficient gene editing via non-viral delivery of CRISPR-Cas9 system using polymeric and hybrid microcarriers. Nanomedicine: Nanotechnology, Biology, and Medicine, 2018, 14(1), 97–108. doi: 10.1016/j.nano.2017.09.001
  256. Lockhart, J.N.; Spoonmore, T.J.; McCurdy, M.W.; Rogers, B.R.; Guelcher, S.A.; Harth, E. Poly(glycidol) Coating on Ultrahigh Molecular Weight Polyethylene for Reduced Biofilm Growth. ACS Applied Materials & Interfaces, 2018, 10(4), 4050–4056. doi: 10.1021/acsami.7b15981
  257. Ding, L.; Jiang, Y.; Zhang, J.; Klok, H.-A.; Zhong, Z. pH-Sensitive Coiled-Coil Peptide-Cross-Linked Hyaluronic Acid Nanogels: Synthesis and Targeted Intracellular Protein Delivery to CD44 Positive Cancer Cells. Biomacromolecules, 2018, 19(2), 555–562. doi: 10.1021/acs.biomac.7b01664
  258. Park, C.-K.; Hong, S.K.; Kim, Y.H.; Cho, H. Nucleic acid-binding fluorochromes and nanoparticles: Structural aspects of binding affinity and fluorescence intensity. Macromolecular Research, 2018, 26(2), 204–209. doi: 10.1007/s13233-018-6053-8
  259. Kong, J.-N.; Zhu, Z.; Itokazu, Y.; Wang, G.; Dinkins, M.B.; Zhong, L.; Lin, H.-P.; Elsherbini, A.; Leanhart, S.; Jiang, X.; Qin, H.; Zhi, W.; Spassieva, S.D.; Bieberich, E. Novel function of ceramide for regulation of mitochondrial ATP release in astrocytes. Journal of Lipid Research, 2018, 59(3), 488–506. doi: 10.1194/jlr.M081877
  260. Huang, D.; Chen, Y.-S.; Xu, Q.; Hanes, J.; Rupenthal, I.D. Effects of enzymatic degradation on dynamic mechanical properties of the vitreous and intravitreal nanoparticle mobility. European Journal of Pharmaceutical Sciences, 2018, 118, 124–133. doi: 10.1016/j.ejps.2018.03.023
  261. Fatona, A.; Berry, R.M.; Brook, M.A.; Moran-Mirabal, J.M. Versatile Surface Modification of Cellulose Fibres and Cellulose Nanocrystals through Modular Triazinyl Chemistry. Chemistry of Materials, 2018, 30(7), 2424–2435. doi: 10.1021/acs.chemmater.8b00511
  262. Huang, Q.; Li, S.; Ding, Y.; Yin, H.; Wang, L.-H.; Wang, R. Macrocycle-Wrapped Polyethylenimine for Gene Delivery with Reduced Cytotoxicity. Biomaterials Science, 2018, 6(5), 1031–1039. doi: 10.1039/C8BM00022K
  263. Matsuoka, D.; Watanabe, H.; Shimizu, Y.; Kimura, H.; Yagi, Y.; Kawai, R.; Ono, M.; Saji, H. Structure–activity relationships of succinimidyl-Cys-C (O)-Glu derivatives with different near-infrared fluorophores as optical imaging probes for prostate-specific membrane antigen. Bioorganic & Medicinal Chemistry, 2018, 26(9), 2291–2301. doi: 10.1016/j.bmc.2018.03.015

2017

  1. Mattila, J.T.; Beaino, W.; Maiello, P.; Coleman, M.T.; White, A.G.; Scanga, C.A.; Flynn, J.A.; Anderson, C.J. Positron Emission Tomography Imaging of Macaques with Tuberculosis Identifies Temporal Changes in Granuloma Glucose Metabolism and Integrin α4β1-Expressing Immune Cells. Journal of immunology, 2017, 199(2), 806–815. doi: 10.4049/jimmunol.1700231
  2. Chen, J.; Ding, J.; Wang, Y.; Cheng, J.; Ji, S.; Zhuang, X.; Chen, X. Sequentially Responsive Shell-Stacked Nanoparticles for Deep Penetration into Solid Tumors. Advanced Materials, 2017, 29(32), 1701170. doi: 10.1002/adma.201701170
  3. Shields, K.J.; Wu, C. Differential Adipose Tissue Proteomics. Methods in Molecular Biology, 2017, 1788, 243–250. doi: 10.1007/7651_2017_80
  4. Evans, L.E.; Jones, K.; Cheeseman, M.D. Targeting secondary protein complexes in drug discovery: studying the druggability and chemical biology of the HSP70/BAG1 complex. Chemical Communications, 2017, 53(37), 5167–5170. doi: 10.1039/c7cc01376k
  5. Wang, C.; Niederstrasser, H.; Douglas, P.M.; Lin, R.; Jaramillo, J.; Li, Y.; Olswald, N.W.; Zhou, A.; McMillan, E.A.; Mendiratta, S.; Wang, Z.; Zhao, T.; Lin, Z.; Luo, M.; Huang, G.; Brekken, R.A.; Posner, B.A.; MacMillan, J.B.; Gao, J.; White, M.A. Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan. Nature Communications, 2017, 8, 2270. doi: 10.1038/s41467-017-02332-3
  6. Maximova, N.; Koroleva, A.; Sitnikova, T.; Khanaev, I.; Bukin, Y.; Kirilchik, S. Age Dynamics of Telomere Length of Baikal Gastropods is Sex Specific and Multidirectional. Folia Biologica (Kraków), 2017, 65(4), 187–197. doi: 10.3409/fb65_4.187
  7. Lee, N.K.; Lee, E.J.; Kim, S.; Nam, G.-H.; Kih, M.; Hong, Y.; Jeong, C.; Yang, Y.; Byun, Y.; Kim, I.-S. Ferritin nanocage with intrinsically disordered proteins and affibody: A platform for tumor targeting with extended pharmacokinetics. Journal of Controlled Release, 2017, 267, 172–180. doi: 10.1016/j.jconrel.2017.08.014
  8. Madl, C.M.; LeSavage, B.L.; Dewi, R.E.; Dinh, C.B.; Stowers, R.S.; Khariton, M.; Lampe, K.J.; Nguyen, D.; Chaudhuri, O.; Enejder, A.; Heilshorn, S.C. Maintenance of neural progenitor cell stemness in 3D hydrogels requires matrix remodelling. Nature Materials, 2017, 16(12), 1233–1242. doi: 10.1038/nmat5020
  9. Hu, H.; Xiao, C.; Wu, H.; Li, Y.; Zhou, Q.; Tang, Y.; Yu, C.; Yang, X.; Li, Z. Nanocolloidosomes with Selective Drug Release for Active Tumor-Targeted Imaging-Guided Photothermal/Chemo Combination Therapy. ACS Applied Materials & Interfaces, 2017, 9(48), 42225–42238. doi: 10.1021/acsami.7b14796
  10. Zhou, Z.; Jafari, M.; Sriram, V.; Kim, J.; Lee, J.-Y.; Ruiz-Torres, S.J.; Waltz, S.E. Delayed Sequential Co-Delivery of Gefitinib and Doxorubicin for Targeted Combination Chemotherapy. Molecular Pharmaceutics, 2017, 14(12), 4551–4559. doi: 10.1021/acs.molpharmaceut.7b00669
  11. Chen, G.; Ma, B.; Wang, Y.; Xie, R.; Li, C.; Dou, K.; Gong, S. CuS-Based Theranostic Micelles for NIR-Controlled Combination Chemotherapy and Photothermal Therapy and Photoacoustic Imaging. ACS Applied Materials & Interfaces, 2017, 9(48), 41700–41711. doi: 10.1021/acsami.7b14083
  12. Topolyan, A.P.; Belyaeva, M.; Slyundina, M.S.; Ilyushenkova, V.; Formanovsky, A.A.; Korshun, V.A.; Borisov, R.S. Novel trityl/acridine derivatization agent for analysis of thiols by (matrix-assisted)(nanowire-assisted) laser desorption/ionization and electrospray ionization mass spectrometry. Analytical Methods, 2017, 9(45), 6335–6340. doi: 10.1039/C7AY01965C
  13. Zhou, J.; He, L.; Pang, Z.; Appelman, H.D.; Kuick, R.; Beer, D.G.; Li, M.; Wang, T.D. Identification and validation of FGFR2 peptide for detection of early Barrett's neoplasia. Oncotarget, 2017, 8(50), 87095–87106. doi: 10.18632/oncotarget.19764
  14. Lee, J.-H.; Yang, B.; Lindahl, A.J.; Damaschke, N.; Boersma, M.D.; Huang, W.; Corey, E.; Jarrard, D.F.; Denu, J.M. Identifying dysregulated epigenetic enzyme activity in castrate-resistant prostate cancer development. ACS Chemical Biology, 2017, 12(11), 2804–2814. doi: 10.1021/acschembio.6b01035
  15. Schmidt, N.; Kollewe, A.; Constantin, C.E.; Henrich, S.; Ritzau-Jost, A.; Bildl, W.; Saalbach, A.; Hallermann, S.; Kulik, A.; Fakler, B.; Schulte, U. Neuroplastin and Basigin Are Essential Auxiliary Subunits of Plasma Membrane Ca2+-ATPases and Key Regulators of Ca2+ Clearance. Neuron, 2017, 96(4), 827–838.e9. doi: 10.1016/j.neuron.2017.09.038
  16. Niessen, S.; Dix, M.M.; Barbas, S.; Potter, Z.E.; Lu, S.; Brodsky, O.; Planken, S.; Behenna, D.; Almaden, C.; Gajiwala, K.S.; Ryan, K.; Ferre, R.; Lazear, M.R.; Hayward, M.M.; Kath, J.C.; Cravatt, B.F. Proteome-wide Map of Targets of T790M-EGFR-Directed Covalent Inhibitors. Cell Chemical Biology, 2017, 24(11), 1388–1400.e7. doi: 10.1016/j.chembiol.2017.08.017
  17. Schonhoft, J.D.; Monteiro, C.; Plate, L.; Eisele, Y.S.; Kelly, J.M.; Boland, D.; Parker, C.G.; Cravatt, B.F.; Teruya, S.; Helmke, S.; Maurer, M.; Berk, J.; Sekijima, Y.; Novais, M.; Coelho, T.; Powers, E.T.; Kelly, J.W. Peptide probes detect misfolded transthyretin oligomers in plasma of hereditary amyloidosis patients. Science Translational Medicine, 2017, 9(407), eaam7621. doi: 10.1126/scitranslmed.aam7621
  18. Than, A.; Liang, K.; Xu, S.; Sun, L.; Duan, H.; Xi, F.; Xu, C.; Chen, P. Transdermal Delivery of Anti-Obesity Compounds to Subcutaneous Adipose Tissue with Polymeric Microneedle Patches. Small Methods, 2017, 1(11), 1700269. doi: 10.1002/smtd.201700269
  19. Li, Y.; Han, Z.; Roelle, S.; DeSanto, A.; Sabatelle, R.; Schur, R.; Lu, Z.-R. Synthesis and Assessment of Peptide Gd-DOTA Conjugates Targeting Extradomain B Fibronectin for Magnetic Resonance Molecular Imaging of Prostate Cancer. Molecular Pharmaceutics, 2017, 14(11), 3906–3915. doi: 10.1021/acs.molpharmaceut.7b00619
  20. Feiner-Gracia, N.; Beck, M.; Pujals, S.; Tosi, S.; Mandal, T.; Buske, C.; Linden, M.; Albertazzi, L. Super-Resolution Microscopy Unveils Dynamic Heterogeneities in Nanoparticle Protein Corona. Small, 2017, 13(41), 1701631. doi: 10.1002/smll.201701631
  21. Zabara, A.; Meikle, T.G.; Trenker, R.; Yao, S.; Newman, J.; Peat, T.S.; Separovic, F.; Conn, C.E.; Call, M.J.; Call, M.E.; Landau, E.M.; Drummond, C.J. Lipidic Cubic Phase-Induced Membrane Protein Crystallization: Interplay Between Lipid Structure, Mesophase Properties, and Crystallogenesis. Crystal Growth and Design, 2017, 17(11), 5667–5674. doi: 10.1021/acs.cgd.7b00519
  22. Liu, L.; Zhang, C.; Li, Z.; Wang, C.; Bi, J.; Yin, S.; Wang, Q.; Yu, R.; Liu, Y.D.; Su, Z. Albumin binding domain fusing R/K-X-X-R/K sequence for enhancing tumor delivery of doxorubicin. Molecular Pharmaceutics, 2017, 14(11), 3739–3749. doi: 10.1021/acs.molpharmaceut.7b00497
  23. Liu, Y.; Ji, X.; Liu, J.; Tong, W.W.L.; Askhatova, D.; Shi, J. Tantalum Sulfide Nanosheets as a Theranostic Nanoplatform for Computed Tomography Imaging-Guided Combinatorial Chemo-Photothermal Therapy. Advanced Functional Materials, 2017, 27(39), 1703261. doi: 10.1002/adfm.201703261
  24. Deyaert, E.; Wauters, L.; Guaitoli, G.; Konijnenberg, A.; Leemans, M.; Terheyden, S.; Petrovic, A.; Gallardo, R.; Nederveen-Schippers, L.M.; Athanasopoulos, P.S.; Pots, H.; Van Haastert, P.J.M.; Sobott, F.; Gloeckner, C.J.; Efremov, R.; Kortholt, A.; Versées, W. A homologue of the Parkinson's disease-associated protein LRRK2 undergoes a monomer-dimer transition during GTP turnover. Nature Communications, 2017, 8(1), 1008. doi: 10.1038/s41467-017-01103-4
  25. Park, S.; Shevlin, E.; Vedvyas, Y.; Zaman, M.; Park, S.; Hsu, Y.-M.S.; Min, I.M.; Jin, M.M. Micromolar affinity CAR T cells to ICAM-1 achieves rapid tumor elimination while avoiding systemic toxicity. Scientific Reports, 2017, 7, 14366. doi: 10.1038/s41598-017-14749-3
  26. Zhou, Z.; Liu, S.; Zhang, Y.; Yang, X.; Ma, Y.; Guan, Z.; Wu, Y.; Zhang, L.; Yang, Z. Reductive nanocomplex encapsulation of cRGD-siRNA conjugates for enhanced targeting to cancer cells. International Journal of Nanomedicine, 2017, 12, 7255–7272. doi: 10.2147/ijn.S136726
  27. Xie, J.; Yang, C.; Liu, Q.; Li, J.; Liang, R.; Shen, C.; Zhang, Y.; Wang, K.; Liu, L.; Shezad, K.; Sullivan, M.; Xu, Y.; Shen, G.; Tao, J.; Zhu, J.; Zhang, Z. Encapsulation of Hydrophilic and Hydrophobic Peptides into Hollow Mesoporous Silica Nanoparticles for Enhancement of Antitumor Immune Response. Small, 2017, 13(40), 1701741. doi: 10.1002/smll.201701741
  28. Rachel, N.M.; Toulouse, J.L.; Pelletier, J.N. Transglutaminase-Catalyzed Bioconjugation Using One-Pot Metal-Free Bioorthogonal Chemistry. Bioconjugate Chemistry, 2017, 28(10), 2518–2523. doi: 10.1021/acs.bioconjchem.7b00509
  29. Schäfer, O.; Klinker, K.; Braun, L.; Huesmann, D.; Schultze, J.; Koynov, K.; Barz, M. Combining Orthogonal Reactive Groups in Block Copolymers for Functional Nanoparticle Synthesis in a Single Step. ACS Macro Letters, 2017, 6(10), 1140–1145. doi: 10.1021/acsmacrolett.7b00678
  30. Mitronova, G.Y.; Lukinavičius, G.; Butkevich, A.N.; Kohl, T.; Belov, V.N.; Lehnart, S.E.; Hell, S.W. High-Affinity Functional Fluorescent Ligands for Human β-Adrenoceptors. Scientific Reports, 2017, 7, 12319. doi: 10.1038/s41598-017-12468-3
  31. Xiao, W.; Ruan, S.; Yu, W.; Wang, R.; Hu, C.; Liu, R.; Gao, H. Normalizing tumor vessels to increase the enzyme-induced retention and targeting of gold nanoparticle for breast cancer imaging and treatment. Molecular Pharmaceutics, 2017, 14(10), 3489–3498. doi: 10.1021/acs.molpharmaceut.7b00475
  32. Xu, W.; Ding, J.; Chen, X. Reduction-Responsive Polypeptide Micelles for Intracellular Delivery of Antineoplastic Agent. Biomacromolecules, 2017, 18(10), 3291–3301. doi: 10.1021/acs.biomac.7b00950
  33. Pink, M.; Verma, N.; Zerries, A.; Schmitz-Spanke, S. Dose-dependent response to 3-nitrobenzanthrone exposure in human urothelial cancer cells. Chemical Research in Toxicology, 2017, 30(10), 1855–1864. doi: 10.1021/acs.chemrestox.7b00174
  34. Sharangdhar, T.; Sugimoto, Y.; Heraud-Farlow, J.; Fernández-Moya, S.M.; Ehses, J.; Ruiz de Los Mozos, I.; Ule, J.; Kiebler, M.A. A retained intron in the 3'-UTR of Calm3 mRNA mediates its Staufen2- and activity-dependent localization to neuronal dendrites. EMBO Reports, 2017, 18(10), 1762–1774. doi: 10.15252/embr.201744334
  35. Ozcelik, D.; Jain, A.; Stambaugh, A.; Stott, M.A.; Parks, J.W.; Hawkins, A.; Schmidt, H. Scalable Spatial-Spectral Multiplexing of Single-Virus Detection Using Multimode Interference Waveguides. Scientific Reports, 2017, 7, 12199. doi: 10.1038/s41598-017-12487-0
  36. Zhao, P.; George, J.V.; Li, B.; Amini, N.; Paluh, J.; Wang, J. Clickable Multifunctional Dumbbell Particles for In Situ Multiplex Single-Cell Cytokine Detection. ACS Applied Materials & Interfaces, 2017, 9(38), 32482–32488. doi: 10.1021/acsami.7b08338
  37. Wang, E.; Hunter, C.P. SID-1 Functions in Multiple Roles To Support Parental RNAi in Caenorhabditis elegans. Genetics, 2017, 207(2), 547–557. doi: 10.1534/genetics.117.300067
  38. Han, Z.; Wu, X.; Roelle, S.; Chen, C.; Schiemann, W.P.; Lu, Z.-R. Targeted gadofullerene for sensitive magnetic resonance imaging and risk-stratification of breast cancer. Nature Communications, 2017, 8, 692. doi: Nature Communications
  39. Guttenplan, A.P.M.; Young, L.J.; Matak-Vinkovic, D.; Kaminski, C.F.; Knowles, T.P.J.; Itzhaki, L.S. Nanoscale click-reactive scaffolds from peptide self-assembly. Journal of Nanobiotechnology, 2017, 15, 70. doi: 10.1186/s12951-017-0300-7
  40. Shi, X.; Yu, C.Y.Y.; Su, H.; Kwok, R.T.K.; Jiang, M.; He, Z.; Lam, J.W.Y.; Tang, B.Z. A Red-emissive antibody–AIEgen conjugate for turn-on and wash-free imaging of specific cancer cells. Chemical Science, 2017, 8(10), 7014–7024. doi: 10.1039/C7SC01054K
  41. Machado, Y.; Duinkerken, S.; Hoepflinger, V.; Mayr, M.; Korotchenko, E.; Kurtaj, A.; Pablos, I.; Steiner, M.; Stoecklinger, A.; Lübbers, J.; Schmid, M.; Ritter, U.; Scheiblhofer, S.; Ablinger, M.; Wally, V.; Hochmann, S.; Raninger, A.M.; Strunk, D.; van Kooyk, Y.; Thalhamer, J.; Weiss, R. Synergistic effects of dendritic cell targeting and laser-microporation on enhancing epicutaneous skin vaccination efficacy. Journal of Controlled Release, 2017, 266, 87–99. doi: 10.1016/j.jconrel.2017.09.020
  42. Zhang, L.; Yao, M.; Yan, W.; Liu, X.; Jiang, B.; Qian, Z.; Gao, Y.; Lu, X.-J.; Chen, X.; Wang, Q.-L. Delivery of a chemotherapeutic drug using novel hollow carbon spheres for esophageal cancer treatment. International Journal of Nanomedicine, 2017, 12, 6759–6769. doi: 10.2147/IJN.S142916
  43. Steffen, W.; Ko, F.C.; Patel, J.; Lyamichev, V.; Albert, T.; Benz, J.; Rudolph, M.G.; Bergmann, F.; Streidl, T.; Kratzsch, P.; Boenitz-Dulat, M.; Oelschlaegel, T.; Schraeml, M. Discovery of a microbial transglutaminase enabling highly site-specific labeling of proteins. Journal of Biological Chemistry, 2017, 292(38), 15622–15635. doi: 10.1074/jbc.M117.797811
  44. Park, J.; Choi, J.U.; Kim, K.; Byun, Y. Bile acid transporter mediated endocytosis of oral bile acid conjugated nanocomplex. Biomaterials, 2017, 147, 145–154. doi: 10.1016/j.biomaterials.2017.09.022
  45. Pan, G.; Jia, T.-t.; Huang, Q.-x. Qiu, Y.-y.; Xu, J. Yin, P.-h.; Liu, T. Mesoporous Silica Nanoparticles (MSNs)-Based Organic/Inorganic Hybrid Nanocarriers Loading 5-Fluorouracil for the Treatment of Colon Cancer with Improved Anticancer Efficacy. Colloids and Surfaces, B: Biointerfaces, 2017, 159, 375–385. doi: 10.1016/j.colsurfb.2017.08.013
  46. Huang, Y.; Zhou, J.; Hakamivala, A.; Wu, J.; Hong, Y.; Borrelli, J.; Tang, L. An optical probe for detecting chondrocyte apoptosis in response to mechanical injury. Scientific Reports, 2017, 7, 10906. doi: 10.1038/s41598-017-10653-y
  47. Wei, S.; Perera, M.L.W.; Sakhtemani, R.; Bhagwat, A.S. A novel class of chemicals that react with abasic sites in DNA and specifically kill B cell cancers. PLoS One, 2017, 12, e0185010. doi: 10.1371/journal.pone.0185010
  48. Soni, K.S.; Lei, F.; Desale, S.S.; Marky, L.A.; Cohen, S.M.; Bronich, T.K. Tuning polypeptide-based micellar carrier for efficient combination therapy of ErbB2-positive breast cancer. Journal of Controlled Release, 2017, 264, 276–287. doi: 10.1016/j.jconrel.2017.08.038
  49. Duret, D.; Grassin, A.; Henry, M.; Jacquet, T.; Thoreau, F.; Denis-Quanquin, S.; Coll, J.-L.; Boturyn, D.; Favier, A.; Charreyre, M.-T. "Polymultivalent" Polymer-Peptide Cluster Conjugates for an Enhanced Targeting of Cells Expressing αvβ3 Integrins. Bioconjugate Chemistry, 2017, 28(9), 2241–2245. doi: 10.1021/acs.bioconjchem.7b00362
  50. Kim, J.-w.; Heu, W.; Jeong, S.; Kim, H.-S. Genetically functionalized ferritin nanoparticles with a high-affinity protein binder for immunoassay and imaging. Analytica Chimica Acta, 2017, 988, 81–88. doi: 10.1016/j.aca.2017.07.060
  51. Schneider, J.R.; Carias, A.M.; Bastian, A.R.; Cianci, G.C.; Kiser, P.F.; Veazey, R.S.; Hope, T.J. Long-term direct visualization of passively transferred fluorophore-conjugated antibodies. Journal of Immunological Methods, 2017, 450, 66–72. doi: 10.1016/j.jim.2017.07.009
  52. Verardi, R.; Kim, J.-S.; Ghirlando, R.; Banerjee, A. Structural Basis for Substrate Recognition by the Ankyrin Repeat Domain of Human DHHC17 Palmitoyltransferase. Structure, 2017, 25(9), 1337–1347. doi: 10.1016/j.str.2017.06.018
  53. Mondal, G.; Almawash, S.; Chaudhary, A.K.; Mahato, R.I. EGFR-Targeted Cationic Polymeric Mixed Micelles for Co-delivery of Gemcitabine and miR-205 for treating Advanced Pancreatic Cancer. Molecular Pharmaceutics, 2017, 14(9), 3121–3133. doi: 10.1021/acs.molpharmaceut.7b00355
  54. Chen, Z.; Zhai, M.; Xie, X.Y.; Zhang, Y.; Ma, S.; Li, Z.; Yu, F.; Zhao, B.; Zhang, M.; Yang, Y.; Mei, X. Apoferritin Nanocage for Brain Targeted Doxorubicin Delivery. Molecular Pharmaceutics, 2017, 14(9), 3087–3097. doi: 10.1021/acs.molpharmaceut.7b00341
  55. Gaspar, I.; Wippich, F.; Ephrussi, A. Enzymatic production of single molecule FISH and RNA capture probes. RNA, 2017, 23(10), 1582–1591. doi: 10.1261/rna.061184.117
  56. Li, Z.; Xiong, Y. Cytoplasmic E3 ubiquitin ligase CUL9 controls cell proliferation, senescence, apoptosis and genome integrity through p53. Oncogene, 2017, 36(36), 5212–5218. doi: 10.1038/onc.2017.141
  57. Huang, T.-Y.; Chang, C.-K.; Kao, Y.-F.; Chin, C.-H.; Ni, C.-W.; Hsu, H.-Y.; Hu, N.-J.; Hsieh, L.-C.; Chou, S.-H.; Lee, I.-R.; Hou, M.-H. Parity-dependent hairpin configurations of repetitive DNA sequence promote slippage associated with DNA expansion. Proceedings of the National Academy of Sciences of the USA, 2017, 114(36), 9535–9540. doi: 10.1073/pnas.1708691114
  58. Haimi, P.; Vinskiene, J.; Stepulaitiene, I.; Baniulis, D.; Stanienė, G.; Šikšnianienė, J.B.; Rugienius, R. Patterns of low temperature-Induced accumulation of dehydrins in Rosaceae crops — Evidence for post-translational modification in apple. Journal of Plant Physiology, 2017, 218, 175–181. doi: 10.1016/j.jplph.2017.08.008
  59. Payne, W.M.; Hill, T.K.; Svechkarev, D.; Holmes, M.B.; Sajja, B.R.; Mohs, A.M. Multimodal Imaging Nanoparticles Derived from Hyaluronic Acid for Integrated Preoperative and Intraoperative Cancer Imaging. Contrast Media & Molecular Imaging, 2017, 2017, Article ID 9616791. doi: 10.1155/2017/9616791
  60. Wollhofen, R.; Buchegger, B.; Eder, C.; Jacak, J.; Kreutzer, J.; Klar, T.A. Functional photoresists for sub-diffraction stimulated emission depletion lithography. Optical Materials Express, 2017, 7(7), 2538–2559. doi: 10.1364/ome.7.002538
  61. Wang, H.; Chen, J.; Xu, C.; Shi, L.; Tayier, M.; Zhou, J.; Zhang, J.; Wu, J.; Ye, Z.; Fang, T.; Han, W. Cancer Nanomedicines Stabilized by π–π Stacking between Heterodimeric Prodrugs Enable Exceptionally High Drug Loading Capacity and Safer Delivery of Drug Combinations. Theranostics, 2017, 7(15), 3639–3652. doi: 10.7150/thno.20028
  62. Kovalenko, Y.; Sotiri, I.; Timonen, J.V.I.; Overton, J.C.; Holmes, G.; Aizenberg, J.; Howell, C. Bacterial Interactions with Immobilized Liquid Layers. Advanced Healthcare Materials, 2017, 6(15), 1600948. doi: 10.1002/adhm.201600948
  63. Steele, A.N.; Cai, L.; Truong, V.N.; Edwards, B.B.; Goldstone, A.B.; Eskandari, A.; Mitchell, A.C.; Marquardt, L.M.; Foster, A.A.; Cochran, J.R.; Heilshorn, S.C.; Woo, Y.J. A novel protein-engineered hepatocyte growth factor analog released via a shear-thinning injectable hydrogel enhances post-infarction ventricular function. Biotechnology and Bioengineering, 2017, 114(10), 2379–2389. doi: 10.1002/bit.26345
  64. Wang, F.; Sun, W.; Li, L.; Li, L.; Liu, Y.; Zhang, Z.; Huang, Y. Charge-reversible Multi-functional HPMA Copolymers for Mitochondrial Targeting. ACS Applied Materials & Interfaces, 2017, 9(33), 27563–27574. doi: 10.1021/acsami.7b09693
  65. Fu, L.; Han, L.; Xie, C.; Li, W.; Lin, L.; Pan, S.; Zhou, Y.; Li, Z.; Jin, M.; Zhang, A. Identification of Extracellular Actin As a Ligand for Triggering Receptor Expressed on Myeloid Cells-1 Signaling. Frontiers in Immunology, 2017, 8, 917. doi: 10.3389/fimmu.2017.00917
  66. Zhang, C.; Moonshi, S.S.; Han, Y.; Puttick, S.; Peng, H.; Magoling, B.J.A.; Reid, J.C.; Bernardi, S.; Searles, D.J.; Král, P.; Whittaker, A.K. PFPE-Based Polymeric 19F MRI Agents: A New Class of Contrast Agents with Outstanding Sensitivity. Macromolecules, 2017, 50(15), 5953–5963. doi: 10.1021/acs.macromol.7b01285
  67. Antos, J.M.; Ingram, J.; Fang, T.; Pishesha, N.; Truttmann, M.C.; Ploegh, H.L. Site-Specific Protein Labeling via Sortase-Mediated Transpeptidation. Current Protocols in Protein Science, 2017, 89, 15.3.1–15.3.19. doi: 10.1002/cpps.38
  68. Zhou, Z.; Kennell, C.; Jafari, M.; Lee, J.-Y.; Ruiz-Torres, S.J.; Waltz, S.E.; Lee, J.-H. Sequential Delivery of Erlotinib and Doxorubicin for Enhanced Triple Negative Breast Cancer Treatment Using Polymeric Nanoparticle. International Journal of Pharmaceutics, 2017, 530(1–2), 300–307. doi: 10.1016/j.ijpharm.2017.07.085
  69. Pettersson, J.R.; Lanni, F.; Rule, G.S. Dual lifetimes for complexes between Glutathione-S-transferase (hGSTA1-1) and product-like ligands detected by single-molecule fluorescence imaging. Biochemistry, 2017, 56(31), 4073–4083. doi: 10.1021/acs.biochem.7b00030
  70. Dou, Y.; Chen, Y.; Zhang, X.; Xu, X.; Chen, Y.; Guo, J.; Zhang, D.; Wang, R.; Li, X.; Zhang, J. Non-proinflammatory and responsive nanoplatforms for targeted treatment of atherosclerosis. Biomaterials, 2017, 143, 93–108. doi: 10.1016/j.biomaterials.2017.07.035
  71. Chen, G.; Wang, Y.; Xie, R.; Gong, S. Tumor-targeted pH/redox dual-sensitive unimolecular nanoparticles for efficient siRNA delivery. Journal of Controlled Release, 2017, 259, 105–114. doi: 10.1016/j.jconrel.2017.01.042
  72. Sun, S.; Li, L.; Yang, F.; Wang, X.; Fan, F.; Yang, M.; Chen, C.; Li, X.; Wang, H.-W.; Sui, S.-F. Cryo-EM structures of the ATP-bound Vps4E233Q hexamer and its complex with Vta1 at near-atomic resolution. Nature Communications, 2017, 8, 16064. doi: 10.1038/ncomms16064
  73. Tsai, M.-H.; Pan, C.-H.; Peng, C.-L.; Shieh, M.-J. Panitumumab-Conjugated Pt-Drug Nanomedicine for Enhanced Efficacy of Combination Targeted Chemotherapy against Colorectal Cancer. Advanced Healthcare Materials, 2017, 6(13), 1700111. doi: 10.1002/adhm.201700111
  74. Kozlowska, A.K.; Florczak, A.; Smialek, M.; Dondajewska, E.; Mackiewicz, A.; Kortylewski, M.; Dams-Kozlowska, H. Functionalized bioengineered spider silk spheres improve nuclease resistance and activity of oligonucleotide therapeutics providing a strategy for cancer treatment. Acta Biomaterialia, 2017, 59, 221–233. doi: 10.1016/j.actbio.2017.07.014
  75. Zhang, C.; Yang, L.; Ding, Y.; Wang, Y.; Lan, L.; Ma, Q.; Chi, X.; Wei, P.; Zhao, Y.; Steinbüchel, A.; Zhang, H.; Liu, P. Bacterial lipid droplets bind to DNA via an intermediary protein that enhances survival under stress. Nature Communications, 2017, 8, 15979. doi: 10.1038/ncomms15979
  76. Suleimanov, I.; Gabor, M.; Lionel, S.; Bousseksou, A. Near-infrared luminescence switching in a spin-crossover polymer nanocomposite. European Journal of Inorganic Chemistry, 2017, 28, 3446–3451. doi: 10.1002/ejic.201700426
  77. Merjaneh, M.; Langlois, A.; Larochelle, S.; Cloutier, C.B.; Ricard-Blum, S.; Moulin, V.J. Pro-angiogenic capacities of microvesicles produced by skin wound myofibroblasts. Angiogenesis, 2017, 20(3), 385–398. doi: 10.1007/s10456-017-9554-9
  78. Segura-Ibarra, V.; Cara, F.E.; Wu, S.; Iruegas-Nunez, D.A.; Wang, S.; Ferrari, M.; Ziemys, A.; Valderrabano, M.; Blanco, E. Nanoparticles administered intrapericardially enhance payload myocardial distribution and retention. Journal of Controlled Release, 2017, 262, 18–27. doi: 10.1016/j.jconrel.2017.07.012
  79. Wilson, D.R.; Routkevitch, D.; Rui, Y.; Mosenia, A.; Wahlin, K.J.; Quinones-Hinojosa, A.; Zack, D.J.; Green, J.J. A Triple-Fluorophore Labeled Nucleic Acid pH Nanosensor to Investigate Non-Viral Gene Delivery. Molecular Therapy, 2017, 25(7), 1697–1709. doi: 10.1016/j.ymthe.2017.04.008
  80. Lin, P.-Y.; Chuang, E.-Y.; Chiu, Y.-H.; Chen, H.-L.; Lin, K.-J.; Juang, J.-H.; Chiang, C.-H.; Mi, F.-L.; Sung, H.-W. Safety and efficacy of self-assembling bubble carriers stabilized with sodium dodecyl sulfate for oral delivery of therapeutic proteins. Journal of Controlled Release, 2017, 259, 168–175. doi: 10.1016/j.jconrel.2016.12.018
  81. Xu, X.; Saw, P.E.; Tao, W.; Li, Y.; Ji, X.; Yu, M.; Mahmoudi, M.; Rasmussen, J.; Ayyash, D.; Zhou, Y.; Farokhzad, O.C.; Shi, J. Tumor Microenvironment-Responsive Multistaged Nanoplatform for Systemic RNAi and Cancer Therapy. Nano Letters, 2017, 17(7), 4427–4435. doi: 10.1021/acs.nanolett.7b01571
  82. Loebel, C.; Rodell, C.B.; Chen, M.H.; Burdick, J.A. Shear-thinning and self-healing hydrogels as injectable therapeutics and for 3D-printing. Nature Protocols, 2017, 12(8), 1521–1541. doi: 10.1038/nprot.2017.053
  83. Rosier, B.J.H.M.; Cremers, G.A.O.; Engelen, W.; Merkx, M.; Brunsveld, L.; de Greef, T.F.A. Incorporation of native antibodies and Fc-fusion proteins on DNA nanostructures via a modular conjugation strategy. Chemical Communications, 2017, 53, 7393–7396. doi: 10.1039/c7cc04178k
  84. Barnett, D.; Liu, Y.; Partyka, K.; Huang, Y.; Tang, H.; Hostetter, G.; Brand, R.E.; Singhi, A.D.; Drake, R.R.; Haab, B.B. The CA19-9 and Sialyl-TRA Antigens Define Separate Subpopulations of Pancreatic Cancer Cells. Scientific Reports, 2017, 7, 4020. doi: 10.1038/s41598-017-04164-z
  85. Zhao, Y.; Wang, Y.; Ran, F.; Cui, Y.; Liu, C.; Zhao, Q.; Gao, Y.; Wang, D.; Wang, S. A comparison between sphere and rod nanoparticles regarding their in vivo biological behavior and pharmacokinetics. Scientific Reports, 2017, 7, 4131. doi: 10.1038/s41598-017-03834-2
  86. Seeger, C.; Talibov, V.O.; Danielson, U.H. Biophysical analysis of the dynamics of calmodulin interactions with neurogranin and Ca2+/calmodulin-dependent kinase II. Journal of Molecular Recognition, 2017, 30(8), e2621. doi: 10.1002/jmr.2621
  87. Routh, A.; Ji, P.; Jaworski, E.; Xia, Z.; Li, W.; Wagner, E.J. Poly(A)-ClickSeq: click-chemistry for next-generation 3′-end sequencing without RNA enrichment or fragmentation. Nucleic Acids Research, 2017, 45(12), e112. doi: 10.1093/nar/gkx286
  88. Han, S.; Son, H.Y.; Kang, B.; Jang, E.; Ki, J.; Lee, N.G.; Park, J.; Shin, M.-K.; Mun, B.; Min, J.-K.; Haam, S. Fluorescent nanoswitch for monitoring specific pluripotency-related microRNAs of induced pluripotent stem cells: Development of polyethyleneimineoligonucleotide hybridization probes. Nano Research, 2017, 10(8), 2545–2559. doi: 10.1007/s12274-016-1403-4
  89. Sikorskaite-Gudziuniene, S.; Haimi, P.; Gelvonauskiene, D.; Stanys, V. Nuclear proteome analysis of apple cultivar ‘Antonovka’ accessions in response to apple scab (Venturia inaequalis). European Journal of Plant Pathology, 2017, 148(4), 771–784. doi: 10.1007/s10658-016-1131-3
  90. Bloch, M.B.D.; Yavin, E.; Nissan, A.; Ariel, I.; Kenett, R.; Brass, D.; Rubinstein, A. The effect of linker type and recognition peptide conjugation chemistry on tissue affinity and cytotoxicity of charged polyacrylamide. Journal of Controlled Release, 2017, 257, 102–117. doi: 10.1016/j.jconrel.2016.06.038
  91. Ruan, S.; Xiao, W.; Hu, C.; Zhang, H.; Rao, J.; Wang, S.; Wang, X.; He, Q.; Gao, H. Ligand Mediated and Enzyme-Directed Precise Targeting and Retention for Enhanced Treatment of Glioblastoma. ACS Applied Materials & Interfaces, 2017, 9(24), 20348–20360. doi: 10.1021/acsami.7b02303
  92. Zhou, Z.; Yan, Y.; Hu, K.; Zou, Y.; Li, Y.; Ma, R.; Zhang, Q.; Cheng, Y. Autophagy inhibition enabled efficient photothermal therapy at a mild temperature. Biomaterials, 2017, 141, 116–124. doi: 10.1016/j.biomaterials.2017.06.030
  93. Treerattrakoon, K., Chanthima, W.; Apiwat, C.; Dharakul, T.; Bamrungsap, S. Oriented conjugation of antibodies against~the epithelial cell adhesion molecule on fluorescently doped silica nanoparticles for flow-cytometric determination and in vivo imaging of EpCAM, a biomarker for colorectal cancer. Microchimica Acta, 2017, 184(7), 1941–1950. doi: 10.1007/s00604-017-2211-6
  94. Summer, D.; Grossrubatscher, L.; Petrik, M.; Michalcikova, T.; Novy, Z.; Rangger, C.; Klingler, M.; von Guggenberg, E.; Haubner, R.; Kaeopookum, P.; Haas, H.; Decristoforo, C. Developing targeted hybrid imaging probes by chelator scaffolding. Bioconjugate Chemistry, 2017, 28(6), 1722–1733. doi: 10.1021/acs.bioconjchem.7b00182
  95. Mateju, D.; Franzmann, T.M.; Patel, A.; Kopach, A.; Boczek, E.E.; Maharana, S.; Lee, H.O.; Carra, S.; Hyman, A.A.; Alberti, S. An aberrant phase transition of stress granules triggered by misfolded protein and prevented by chaperone function. The EMBO Journal, 2017, 36(12), 1669–1687. doi: 10.15252/embj.201695957
  96. O'Mary, H.L.; Aldayel, A.M.; Valdes, S.A.; Naguib, Y.W.; Li, X.; Salvady, K.; Cui, Z. Acid-sensitive sheddable PEGylated, mannose-modified nanoparticles increase the delivery of betamethasone to chronic inflammation sites in a mouse model. Molecular Pharmaceutics, 2017, 14(6), 1929–1937. doi: 10.1021/acs.molpharmaceut.7b00024
  97. LaBoda, C.D.; Lebeck, A.R.; Dwyer, C.L. An Optically Modulated Self-Assembled Resonance Energy Transfer Pass Gate. Nano Letters, 2017, 17(6), 3775–3781. doi: 10.1021/acs.nanolett.7b01112
  98. Yang, H.Y.; Jang, M.-S.; Li, Y.; Lee, J.H.; Lee, D.S. Multifunctional and Redox-Responsive Self-Assembled Magnetic Nanovectors for Protein Delivery and Dual-Modal Imaging. ACS Applied Materials & Interfaces, 2017, 9(22), 19184–19192. doi: 10.1021/acsami.7b03747
  99. Guo, L.Y.; Allu, P.K.; Zandarashvili, L.; McKinley, K.L.; Sekulic, N.; Dawicki-McKenna, J.M.; Fachinetti, D.; Logsdon, G.A.; Jamiolkowski, R.M.; Cleveland, D.W.; Cheeseman, I.M.; Black, B.E. Centromeres are maintained by fastening CENP-A to DNA and directing an arginine anchor-dependent nucleosome transition. Nature Communications, 2017, 8, 15775. doi: 10.1038/ncomms15775
  100. Wang, Y.; Malcolm, D.W.; Benoit, D.S.W. Controlled and sustained delivery of siRNA/NPs from hydrogels expedites bone fracture healing. Biomaterials, 2017, 139, 127–138. doi: 10.1016/j.biomaterials.2017.06.001
  101. Shabanpoor, F.; Hammond, S.M.; Abendroth, F.; Hazell, G.; Wood, M.J.A.; Gait, M.J. Identification of a Peptide for Systemic Brain Delivery of a Morpholino Oligonucleotide in Mouse Models of Spinal Muscular Atrophy. Nucleic Acid Therapeutics, 2017, 27(3), 130–143. doi: 10.1089/nat.2016.0652
  102. Cho, C.-F.; Wolfe, J.M.; Fadzen, C.M.; Calligaris, D.; Hornburg, K.; Chiocca, E.A.; Agar, N.Y.R.; Pentelute, B.L.; Lawler, S.E. Blood-brain-barrier spheroids as an in vitro screening platform for brain-penetrating agents. Nature Communications, 2017, 8, 15623. doi: 10.1038/ncomms15623
  103. Wang, Y.; Wang, L.; Chen, G.; Gong, S. Carboplatin-Complexed and cRGD-Conjugated Unimolecular Nanoparticles for Targeted Ovarian Cancer Therapy. Macromolecular Bioscience, 2017, 17(5), 1600292. doi: 10.1002/mabi.201600292
  104. Maity, S.; Hashemi, M.; Lyubchenko, Y.L. Nano-assembly of amyloid β peptide: role of the hairpin fold. Scientific Reports, 2017, 7, 2344. doi: 10.1038/s41598-017-02454-0
  105. Lee, Y.; Kischuk, E.; Crist, S.; Ratliff, T.L.; Thompson, D.H. Targeting and Internalization of Liposomes by Bladder Tumor Cells Using a Fibronectin Attachment Protein-Derived Peptide–Lipopolymer Conjugate. Bioconjugate Chemistry, 2017, 28(5), 1481–1490. doi: 10.1021/acs.bioconjchem.7b00153
  106. Sun, W.; Li, L.; Yang, Q.-Q.; Zhang, Z.-R.; Huang, Y. Two birds, one stone: dual targeting of the cancer cell surface and subcellular mitochondria by the galectin-3-binding peptide G3-C12. Acta Pharmacologica Sinica, 2017, 38(6), 806–822. doi: 10.1038/aps.2016.137
  107. Zietzer, A.; Buschmann, E.E.; Janke, D.; Li, L.; Brix, M.; Meyborg, H.; Stawowy, P.; Jungk, C.; Buschmann, I.; Hillmeister, P. Acute Physical Exercise and Long-Term Individual Shear Rate Therapy Increase Telomerase Activity in Human Peripheral Blood Mononuclear Cells. Acta Physiologica, 2017, 220(2), 251–262. doi: 10.1111/apha.12820
  108. Zhang, K.; Zhang, Y.; Li, Z.; Li, N.; Feng, N. Essential oil-mediated glycerosomes increase transdermal paeoniflorin delivery: optimization, characterization, and evaluation in vitro and in vivo. International Journal of Nanomedicine, 2017, 12, 3521–3532. doi: 10.2147/ijn.s135749
  109. George, J.T.; Srivatsan, S.G. Vinyluridine as a Versatile Chemoselective Handle for the Post-transcriptional Chemical Functionalization of RNA. Bioconjugate Chemistry, 2017, 28(5), 1529–1536. doi: 10.1021/acs.bioconjchem.7b00169
  110. Matsuo, Y.; Maurer, S.P.; Surrey, T.; Toda, T. Purification and characterisation of the fission yeast Ndc80 complex. Protein Expression and Purification, 2017, 135, 61–69. doi: 10.1016/j.pep.2017.05.002
  111. Baranova, N.; Loose, M. Single-molecule measurements to study polymerization dynamics of FtsZ-FtsA copolymers. Methods in Cell Biology, 2017, 137, 355–370. doi: 10.1016/bs.mcb.2016.03.036
  112. Lee, J.Y.; Kim, S.E.; Yun, Y.-P.; Choi, S.-W.; Jeon, D.-I.; Kim, H.-J.; Park, K.; Song, H.-R. Osteogenesis and new bone formation of alendronate-immobilized porous PLGA microspheres in a rat calvarial defect model. Journal of Industrial and Engineering Chemistry, 2017, 52, 277–286. doi: 10.1016/j.jiec.2017.03.057
  113. Goto, A.; Yen, H.-C.; Anraku, Y.; Fukushima, S.; Lai, P.-S.; Kato, M.; Kishimura, A.; Kataoka, K. Facile Preparation of Delivery Platform of Water-Soluble Low-Molecular-Weight Drugs Based on Polyion Complex Vesicle (PICsome) Encapsulating Mesoporous Silica Nanoparticle. ACS Biomaterials Science & Engineering, 2017, 3(5), 807–815. doi: 10.1021/acsbiomaterials.6b00562
  114. Balasso, A.; Salmaso, S.; Pontisso, P.; Rosato, A.; Quarta, S.; Malfanti, A.; Mastrotto, F.; Caliceti, P. Re-programming pullulan for targeting and controlled release of doxorubicin to the hepatocellular carcinoma cells. European Journal of Pharmaceutical Sciences, 2017, 103, 104–115. doi: 10.1016/j.ejps.2017.02.016
  115. Jaworski, E.; Routh, A. Parallel ClickSeq and Nanopore sequencing elucidates the rapid evolution of defective-interfering RNAs in Flock House virus. PLOS Pathogens, 2017, 13(5), e1006365. doi: 10.1371/journal.ppat.1006365
  116. Ta, H.T.; Li, Z.; Hagemeyer, C.E.; Cowin, G.; Zhang, S.; Palasubramaniam, J.; Alt, K.; Wang, X.; Peter, K.; Whittaker, A.K. Molecular imaging of activated platelets via antibody-targeted ultra-small iron oxide nanoparticles displaying unique dual MRI contrast. Biomaterials, 2017, 134, 31–42. doi: 10.1016/j.biomaterials.2017.04.037
  117. Zhang, L.; Fang, Y.; Kopeček, J.; Yang, J. A new construct of antibody-drug conjugates for treatment of B-cell non-Hodgkin's lymphomas. European Journal of Pharmaceutical Sciences, 2017, 103, 36–46. doi: 10.1016/j.ejps.2017.02.034
  118. Heller, D.; Helmerhorst, E.J.; Oppenheim, F.G. Saliva and Serum Protein Exchange at the Tooth Enamel Surface. Journal of Dental Research, 2017, 96(4), 437–443. doi: 10.1177/0022034516680771
  119. Wilson, D.R.; Mosenia, A.; Suprenant, M.P.; Upadhya, R.; Routkevitch, D.; Meyer, R.A.; Quinones-Hinojosa, A.; Green, J.J. Continuous Microfluidic Assembly of Biodegradable Poly(beta-amino ester)/DNA Nanoparticles for Enhanced Gene Delivery. Journal of Biomedical Materials Research. Part A, 2017, 105(6), 1813–1825. doi: 10.1002/jbm.a.36033
  120. Brillault, L.; Jutras, P.V.; Dashti, N.; Thuenemann, E.C.; Morgan, G.; Lomonossoff, G.P.; Landsberg, M.J.; Sainsbury, F. Engineering Recombinant Virus-like Nanoparticles from Plants for Cellular Delivery. ACS Nano, 2017, 11(4), 3476–3484. doi: 10.1021/acsnano.6b07747
  121. Daryaee, F.; Zhang, Z.; Gogarty, K.R.; Li, Y.; Merino, J.; Fisher, S.L.; Tonge, P.J. A quantitative mechanistic PK/PD model directly connects Btk target engagement and in vivo efficacy. Chemical Science, 2017, 8(5), 3434–3443. doi: 10.1039/c6sc03306g
  122. Qu, J.-B.; Chapman, R.; Chen, F.; Lu, H.; Stenzel, M.H. Swollen Micelles for the Preparation of Gated, Squeezable, pH-Responsive Drug Carriers. ACS Applied Materials & Interfaces, 2017, 9(16), 13865–13874. doi: 10.1021/acsami.7b01120
  123. Yang, X.; Wang, Z.; Xiang, Z.; Li, D.; Hu, Z.; Cui, W.; Geng, L.; Fang, Q. Peptide probes derived from pertuzumab by molecular dynamics modeling for HER2 positive tumor imaging. PLoS Computational Biology, 2017, 13(4), e1005441. doi: 10.1371/journal.pcbi.1005441
  124. Perez-Anes, A.; Szarpak-Jankowska, A.; Jary, D.; Auzély-Velty, R. β-CD-Functionalized Microdevice for Rapid Capture and Release of Bacteria. ACS Applied Materials & Interfaces, 2017, 9(16), 13928–13938. doi: 10.1021/acsami.7b02194
  125. Bak, D.W.; Pizzagalli, M.D.; Weerapana, E. Identifying Functional Cysteine Residues in the Mitochondria. ACS Chemical Biology, 2017, 12(4), 947–957. doi: 10.1021/acschembio.6b01074
  126. Han, Z.; Li, Y.; Roelle, S.; Zhou, Z.; Liu, Y.; Sabatelle, R.; DeSanto, A.; Yu, X.; Zhu, H.; Magi-Galluzzi, C.; Lu, Z.-R. A Targeted Contrast Agent Specific to an Oncoprotein in Tumor Microenvironment with the Potential for Detection and Risk Stratification of Prostate Cancer with MRI. Bioconjugate Chemistry, 2017, 28(4), 1031–1040. doi: 10.1021/acs.bioconjchem.6b00719
  127. Tondera, C.; Wieduwild, R.; Röder, E.; Werner, C.; Zhang, Y.; Pietzsch, J. In Vivo Examination of an Injectable Hydrogel System Crosslinked by Peptide-Oligosaccharide Interaction in Immunocompetent Nude Mice. In Vivo Examination of an Injectable Hydrogel System Crosslinked by Peptide-Oligosaccharide Interaction in Immunocompetent Nude Mice, 2017, 27(15), 1605189. doi: 10.1002/adfm.201605189
  128. Tang, X.-L.; Yuan, C.-H.; Ding, Q.; Zhou, Y.; Pan, Q.; Zhang, X.-L. Selection and identification of specific glycoproteins and glycan biomarkers of macrophages involved in Mycobacterium tuberculosis infection. Tuberculosis, 2017, 104, 95–106. doi: 10.1016/j.tube.2017.03.010
  129. Zhang, Z.; Yomo, D.; Gradinaru, C. Choosing the right fluorophore for single-molecule fluorescence studies in a lipid environment. Biochimica et Biophysica Acta – Biomembranes, 2017, 1859(7), 1242–1253. doi: 10.1016/j.bbamem.2017.04.001
  130. Revalde, J.L.; Li, Y.; Wijeratne, T.S.; Bugde, P.; Hawkins, B.C.; Rosengren, R.J.; Paxton, J.W. Curcumin and its cyclohexanone analogue inhibited human Equilibrative nucleoside transporter 1 (ENT1) in pancreatic cancer cells. European Journal of Pharmacology, 2017, 803, 167–173. doi: 10.1016/j.ejphar.2017.03.055
  131. Yin, M.; Bao, Y.; Gao, X.; Wu, Y.; Sun, Y.; Zhao, X.; Xu, H.; Zhang, Z.; Tan, S. Redox/pH dual-sensitive hybrid micelles for targeting delivery and overcoming multidrug resistance of cancer. Journal of Materials Chemistry B, 2017, 5(16), 2964–2978. doi: 10.1039/c6tb03282f
  132. Taskova, M.; Uhd, J.; Miotke, L.; Kubit, M.; Bell, J.; Ji, H.P.; Astakhova, K. Tandem Oligonucleotide Probe Annealing and Elongation To Discriminate Viral Sequence. Analytical Chemistry, 2017, 89(8), 4363–4366. doi: 10.1021/acs.analchem.7b00646
  133. Glass, J.J.; Li, Y.; De Rose, R.; Johnston, A.P.R.; Czuba, E.I.; Khor, S.Y.; Quinn, J.F.; Whittaker, M.R.; Davis, T.P.; Kent, S.J. Thiol-Reactive Star Polymers Display Enhanced Association with Distinct Human Blood Components. ACS Applied Materials & Interfaces, 2017, 9(14), 12182-12194. doi: 10.1021/acsami.6b15942
  134. Planken, S.; Behenna, D.C.; Nair, S.K.; Johnson, T.O.; Nagata, A.; Almaden, C.; Bailey, S.; Ballard, T.E.; Bernier, L.; Cheng, H. et al. Discovery of N-((3R, 4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl) amino)-9-methyl-9H-purin-2-yl) pyrrolidine-3-yl) acrylamide (PF-06747775) Through Structure-Based Drug Design; ... Journal of Medicinal Chemistry, 2017, 60(7), 3002–3019. doi: 10.1021/acs.jmedchem.6b01894
  135. Sacoman, J.L.; Dagda, R.Y.; Burnham-Marusich, A.R.; Dagda, R.K.; Berninsone, P.M. Mitochondrial O-GlcNAc transferase (mOGT) regulates mitochondrial structure, function and survival in HeLa cells. Journal of Biological Chemistry, 2017, 292(11), 4499–4518. doi: 10.1074/jbc.M116.726752
  136. Zhang, C.; Zhao, X.; Guo, S.; Lin, T.; Guo, H. Highly effective photothermal chemotherapy with pH-responsive polymer-coated drug-loaded melanin-like nanoparticles. International Journal of Nanomedicine, 2017, 12, 1827–1840. doi: 10.2147/ijn.s130539
  137. Bian, Y.; Deng, X.; Yan, X.; Zhou, J.; Yuan, L.; Yan, Y. Integrated proteomic analysis of Brachypodium distachyon roots and leaves reveals a synergistic network in the response to drought stress and recovery. Scientific Reports, 2017, 7, 46183. doi: 10.1038/srep46183
  138. Perillo, E.; Hervé-Aubert, K.; Allard-Vannier, E.; Falanga, A.; Galdiero, S.; Chourpa, I. Synthesis and in vitro evaluation of fluorescent and magnetic nanoparticles functionalized with a cell penetrating peptide for cancer theranosis. Journal of Colloid and Interface Science, 2017, 499, 209–217. doi: 10.1016/j.jcis.2017.03.106
  139. Malinovskaya, Y.; Melnikov, P.; Baklaushev, V.; Gabashvili, A.; Osipova, N.; Mantrov, S.; Ermolenko, Y.; Maksimenko, O.; Gorshkova, M.; Balabanyan, V.; Kreuter, J.; Gelperina, S. Delivery of doxorubicin-loaded PLGA nanoparticles into U87 human glioblastoma cells. International Journal of Pharmaceutics, 2017, 524(1–2), 77–90. doi: 10.1016/j.ijpharm.2017.03.049
  140. Kubota, T.; Durek, T.; Dang, B.; Finol-Urdaneta, R.K.; Craik, D.J.; Kent, S.B.H.; French, R.J.; Bezanilla, F.; Correa, A.M. Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET. Proceedings of the National Academy of Sciences of the U.S.A., 2017, 114(10), E1857–1865. doi: 10.1073/pnas.1700453114
  141. Wong, A.S.M.; Czuba, E.; Chen, M.Z.; Yuen, D.; Cupic, K.I.; Yang, S.; Hodgetts, R.Y.; Selby, L.I.; Johnston, A.P.R.; Such, G.K. pH-Responsive Transferrin-pHlexi Particles Capable of Targeting Cells in Vitro. ACS Macro Letters, 2017, 6, 315–320. doi: 10.1021/acsmacrolett.7b00044
  142. Taskova, M.; Madsen, C.S.; Jensen, K.J.; Hansen, L.H.; Vester, B.; Astakhova, K. Antisense oligonucleotides internally labeled with peptides show improved target recognition and stability to enzymatic degradation. Bioconjugate Chemistry, 2017, 28(3), 768–774. doi: 10.1021/acs.bioconjchem.6b00567
  143. Gulati, N.M.; Pitek, A.S.; Steinmetz, N.F.; Stewart, P.L. Cryo-electron tomography investigation of serum albumin-camouflaged tobacco mosaic virus nanoparticles. Nanoscale, 2017, 9(10), 3408–3425. doi: 10.1039/c6nr06948g
  144. Pan, Y.; Ren, X.; Wang, S.; Li, X.; Luo, X.; Yin, Z. Annexin V-Conjugated Mixed Micelles as a Potential Drug Delivery System for Targeted Thrombolysis. Biomacromolecules, 2017, 18(3), 865–876. doi: 10.1021/acs.biomac.6b01756
  145. Terekhov, S.S.; Smirnov, I.V.; Stepanova, A.V.; Bobik, T.V.; Mokrushina, Y.A.; Ponomarenko, N.A.; Belogurov, A.A.; Rubtsova, M.P.; Kartseva, O.V.; Gomzikova, M.O.; Moskovtsev, A.A.; Bukatin, A.S.; Dubina, M.V.; Kostryukova, E.S.; Babenko, V.V.; Vakhitova, M.T.; Manolov, A.I.; Malakhova, M.V.; Kornienko, M.A.; Tyakht, A.V.; Vanyushkina, A.A.; Ilina, E.N.; Masson, P.; Gabibov, A.g.; Altman, S. Microfluidic droplet platform for ultrahigh-throughput single-cell screening of biodiversity. Proceedings of the National Academy of Sciences of the U.S.A., 2017, 114(10), 2550–2555. doi: 10.1073/pnas.1621226114
  146. Alqahtani, M.S.; Islam, M.S.; Podaralla, S.; Kaushik, R.S.; Reineke, J.J.; Woyengo, T.; Perumal, O. Food Protein-based Core-Shell Nanocarriers for Oral Drug Delivery: Effect of Shell Composition on in-vitro and in-vivo Functional Performance of Zein Nanocarriers. Molecular Pharmaceutics, 2017, 14(3), 757–769. doi: 10.1021/acs.molpharmaceut.6b01017
  147. Wang, T.; Tang, Y.; He, X.; Yan, J.; Wang, C.; Feng, X. Self-Assembled Raspberry-Like Core/Satellite Nanoparticles for Anti-Inflammatory Protein Delivery. ACS Applied Materials & Interfaces, 2017, 9(8), 6902–6907. doi: 10.1021/acsami.6b16277
  148. Li, N.; Cai, H.; Jiang, L.; Hu, J.; Bains, A.; Hu, J.; Gong, Q.; Luo, K.; Gu, Z. Enzyme-Sensitive and Amphiphilic PEGylated Dendrimer-Paclitaxel Prodrug Based Nanoparticles for Enhanced Stability and Anticancer Efficacy. ACS Applied Materials & Interfaces, 2017, 9(8), 6865–6877. doi: 10.1021/acsami.6b15505
  149. Mandracchia, D.; Rosato, A.; Trapani, A.; Chlapanidas, T.; Montagner, I.M.; Perteghella, S.; Di Franco, C.; Torre, M.L.; Trapani, G.; Tripodo, G. Design, synthesis and evaluation of biotin decorated inulin-based polymeric micelles as long-circulating nanocarriers for targeted drug delivery. Nanomedicine: Nanotechnology, Biology, and Medicine, 2017, 13(3), 1245–1254. doi: 10.1016/j.nano.2017.01.001
  150. Diaz-Romero, J.; Kürsener, S.; Kohl, S.; Nesic, D. S100B+A1 CELISA: A Novel Potency Assay and Screening Tool for Redifferentiation Stimuli of Human Articular Chondrocytes. Journal of Cellular Physiology, 2017, 232(6), 1559–1570. doi: 10.1002/jcp.25682
  151. Konishcheva, E.V.; Zhumaev, U.E.; Meier, W.P. PEO-b-PCL-b-PMOXA Triblock Copolymers: From Synthesis to Microscale Polymersomes with Asymmetric Membrane. Macromolecules, 2017, 50(4), 1512–1520. doi: 10.1021/acs.macromol.6b02743
  152. Yuan, H.; Wilks, M.Q.; Fakhri, G.E.; Normandin, M.D.; Kaittanis, C.; Josephson, L. Heat-induced-radiolabeling and click chemistry: A powerful combination for generating multifunctional nanomaterials. PLoS One, 2017, 12(2), e0172722. doi: 10.1371/journal.pone.0172722
  153. Chen, L.; Weinmeister, R.; Kralovicova, J.; Eperon, L.P.; Vorechovsky, I.; Hudson, A.J.; Eperon, I.C. Stoichiometries of U2AF35, U2AF65 and snRNP reveal new early spliceosome assembly pathways. Nucleic Acids Research, 2017, 45(4), 2051–2067. doi: 10.1093/nar/gkw860
  154. Peng, Z.; Zhou, J.; Dacy, A.; Zhao, D.; Kearney, V.; Zhou, W.; Tang, L.; Hu, W. Design of a portable imager for near-infrared visualization of cutaneous wounds. Journal of Biomedical Optics, 2017, 22(1), 16010. doi: 10.1117/1.jbo.22.1.016010
  155. Hatai, J.; Motiei, L.; Margulies, D. Analyzing Amyloid Beta Aggregates with a Combinatorial Fluorescent Molecular Sensor. Journal of the American Chemical Society, 2017, 139(6), 2136–2139. doi: 10.1021/jacs.6b10809
  156. Zhou, H.; Tourkakis, G.; Shi, D.; Kim, D.M.; Zhang, H.; Du, T.; Eades, W.C.; Berezin, M.Y. Cell-free measurements of brightness of fluorescently labeled antibodies. Scientific Reports, 2017, 7, 41819. doi: 10.1038/srep41819
  157. Mottas, I.; Milosevic, A.; Petri-Fink, A.; Rothen-Rutishauser, B.; Bourquin, C. A rapid screening method to evaluate the impact of nanoparticles on macrophages. Nanoscale, 2017, 9(7), 2492–2504. doi: 10.1039/c6nr08194k
  158. Duan, Z.; Zhang, Y.; Zhu, H.; Sun, L.; Cai, H.; Li, B.; Gong, Q.; Gu, Z.; Luo, K. Stimuli-Sensitive Biodegradable and Amphiphilic Block Copolymer-Gemcitabine Conjugates Self-assemble Into a Nanoscale Vehicle for Cancer Therapy. ACS Applied Materials & Interfaces, 2017, 9(4), 3474–3486. doi: 10.1021/acsami.6b15232
  159. Long, M.J.C.; Parvez, S.; Zhao, Y.; Surya, S.L.; Wang, Y.; Zhang, S.; Aye, Y. Akt3 is a privileged first responder in isozyme-specific electrophile response. Nature Chemical Biology, 2017, 13(3), 333–338. doi: 10.1038/nchembio.2284
  160. Guldris, N.; Argibay, B.; Gallo, J.; Iglesias-Rey, R.; Carbó-Argibay, E.; Kolen'ko, Y.V.; Campos, F.; Sobrino, T.; Salonen, L.M.; Bañobre-López, M.; Castillo, J.; Rivas, J. Magnetite Nanoparticles for Stem Cell Labeling with High Efficiency and Long-Term in Vivo Tracking. Bioconjugate Chemistry, 2017, 28(2), 362–370. doi: 10.1021/acs.bioconjchem.6b00522
  161. Poudyal, R.R.; Nguyen, P.D.M.; Lokugamage, M.P.; Callaway, M.K.; Gavette, J.V.; Krishnamurthy, R.; Burke, D.H. Nucleobase modification by an RNA enzyme. Nucleic Acids Research, 2017, 45(3), 1345–1354. doi: 10.1093/nar/gkw1199
  162. van der Steen, S.C.H.A.; Raavé, R.; Langerak, S.; van Houdt, L.; van Duijnhoven, S.M.J.; van Lith, S.A.M.; Massuger, L.F.A.G.; Daamen, W.F.; Leenders, W.P.; van Kuppevelt, T.H. Targeting the extracellular matrix of ovarian cancer using functionalized, drug loaded lyophilisomes. European Journal of Pharmaceutics and Biopharmaceutics, 2017, 113, 229–239. doi: 10.1016/j.ejpb.2016.12.010
  163. Stephen, Z.R.; Gebhart, R.N.; Jeon, M.; Blair, A.A.; Ellenbogen, R.G.; Silber, J.R.; Zhang, M. pH-Sensitive O6-Benzylguanosine Polymer Modified Magnetic Nanoparticles for Treatment of Glioblastomas. Bioconjugate Chemistry, 2017, 28(1), 194–202. doi: 10.1021/acs.bioconjchem.6b00545
  164. Jang, D.; Lee, Y.M.; Lee, J.; Doh, J.; Kim, W.J. Remission of lymphoblastic leukaemia in an intravascular fluidic environment by pliable drug carrier with a sliding target ligand. Scientific Reports, 2017, 7, 40739. doi: 10.1038/srep40739
  165. Zhang, R.; Yang, J.; Radford, D.C.; Fang, Y.; Kopeček, J. FRET Imaging of Enzyme-Responsive HPMA Copolymer Conjugate. Macromolecular Bioscience, 2017, 17(1), 1600125. doi: 10.1002/mabi.201600125
  166. Luo, W.; Wen, G.; Yang, L.; Tang, J.; Wang, J.; Wang, J.; Zhang, S.; Zhang, L.; Ma, F.; Xiao, L.; Wang, Y.; Li, Y. Dual-targeted and pH-sensitive Doxorubicin Prodrug-Microbubble Complex with Ultrasound for Tumor Treatment. Theranostics, 2017, 7(2), 452–465
  167. Zhao, Lei and Chen, Guojun and Li, Jun and Fu, Yingmei and Mavlyutov, Timur A. and Yao, Annie and Nickells, Robert W. and Gong, Shaoqin and Guo, Lian-Wang. An intraocular drug delivery system using targeted nanocarriers attenuates retinal ganglion cell degeneration. Journal of Controlled Release, 2017, 247, 153–166. doi: 10.1016/j.jconrel.2016.12.038
  168. Qu, S.; Shi, Y.; Benavides, S.; Hunter, A.J.; Gao, H.; Phillip, W.A. Copolymer Nanofilters with Charge-Patterned Domains for Enhanced Electrolyte Transport. Chemistry of Materials, 2017, 29(2), 762–772. doi: 10.1021/acs.chemmater.6b04660
  169. Hinde, E.; Thammasiraphop, K.; Duong, H.T.T.; Yeow, J.; Karagoz, B.; Boyer, C.; Gooding, J.J.; Gaus, K. Pair correlation microscopy reveals the role of nanoparticle shape in intracellular transport and site of drug release. Nature Nanotechnology, 2017, 12(1), 81–89. doi: 10.1038/nnano.2016.160
  170. Chen, K.; Guo, L.; Zhang, J.; Chen, Q.; Wang, K.; Li, C.; Li, W.; Qiao, M.; Zhao, X.; Hu, H.; Chen, D. A gene delivery system containing nuclear localization signal: increased nucleus import and transfection efficiency with the assistance of RanGAP1. Acta Biomaterialia, 2017, 48, 215–226. doi: 10.1016/j.actbio.2016.11.004
  171. O'Connell, C.L.; Nooney, R.; McDonagh, C. Cyanine5-doped silica nanoparticles as ultra-bright immunospecific labels for model circulating tumour cells in flow cytometry and microscopy. Biosensors and Bioelectronics, 2017, 91, 190–198. doi: 10.1016/j.bios.2016.12.023
  172. Sivak, L.; Subr, V.; Tomala, J.; Rihova, B.; Strohalm, J.; Etrych, T.; Kovar, M. Overcoming multidrug resistance via simultaneous delivery of cytostatic drug and P-glycoprotein inhibitor to cancer cells by HPMA copolymer conjugate. Biomaterials, 2017, 115, 65–80. doi: 10.1016/j.biomaterials.2016.11.013
  173. Braunová A.; Kostka, L.; Sivák, L.; Cuchalová, L.; Hvězdová, Z.; Laga, R.; Filippov, S.; Černoch, P.; Pechar, M.; Janoušková, O.; Šírová, M.; Etrych, T. Tumor-targeted micelle-forming block copolymers for overcoming of multidrug resistance. Journal of Controlled Release, 2017, 245, 41–51. doi: 10.1016/j.jconrel.2016.11.020
  174. Hu, J.; Chen, Y.; Li, Y.; Zhou, Z.; Cheng, Y. A thermo-degradable hydrogel with light-tunable degradation and drug release. Biomaterials, 2017, 112, 133–140. doi: 10.1016/j.biomaterials.2016.10.015
  175. Suarato, G.; Lee, S.-I.; Li, W.; Rao, S.; Khan, T.; Meng, Y.; Shelly, M. Micellar nanocomplexes for biomagnetic delivery of intracellular proteins to dictate axon formation during neuronal development. Biomaterials, 2017, 112, 176–191. doi: 10.1016/j.biomaterials.2016.09.035
  176. Yang, X.; Wang, Z.; Zhang, F.; Zhu, G.; Song, J.; Teng, G.-J.; Niu, G.; Chen, X. Mapping Sentinel Lymph Node Metastasis by Dual-probe Optical Imaging. Theranostics, 2017, 7(1), 153–163. doi: 10.7150/thno.17085
  177. Li, L.; Sun, W.; Li, L.; Liu, Y.; Wu, L.; Wang, F.; Zhou, Z.; Zhang, Z.; Huang, Y. A pH-responsive sequential-disassembly nanohybrid for mitochondrial targeting. Nanoscale, 2017, 9(1), 314–325. doi: 10.1039/c6nr07004c
  178. Wallat, J.D.; Czapar, A.E.; Wang, C.; Wen, A.M.; Wek, K.S.; Yu, X.; Steinmetz, N.F.; Pokorski, J.K. Optical and Magnetic Resonance Imaging Using Fluorous Colloidal Nanoparticles. Biomacromolecules, 2017, 18(1), 103–112. doi: 10.1021/acs.biomac.6b01389
  179. Shen, T.; Xu, X.; Guo, L.; Tang, H.; Diao, T.; Gan, Z.; Zhang, G.; Yu, Q. Efficient Tumor Accumulation, Penetration and Tumor Growth Inhibition Achieved by Polymer Therapeutics: The Effect of Polymer Architectures. Biomacromolecules, 2017, 18(1), 217–230. doi: 10.1021/acs.biomac.6b01533
  180. Sahle, F.F.; Giulbudagian, M.; Bergueiro, J.; Lademann, J.; Calderón, M. Dendritic polyglycerol and N-isopropylacrylamide based thermoresponsive nanogels as smart carriers for controlled delivery of drugs through the hair follicle. Nanoscale, 2017, 9(1), 172–182. doi: 10.1039/c6nr06435c
  181. Zhou, Y.; Li, W.; Wang, M.; Zhang, X.; Zhang, H.; Tong, X.; Xiao, Y. Competitive profiling of celastrol targets in human cervical cancer HeLa cells via quantitative chemical proteomics. Molecular BioSystems, 2017, 13(1), 83–91. doi: 10.1039/c6mb00691d
  182. Cho, W.; Koo, J.Y.; Park, Y.; Oh, K.; Lee, S.; Song, J.-S.; Bae, M.A.; Lim, D.; Lee, D.-S.; Park, S.B:. Treatment of Sepsis Pathogenesis with High Mobility Group Box Protein 1-Regulating Anti-inflammatory Agents. Journal of Medicinal Chemistry, 2017, 60(1), 170–179. doi: 10.1021/acs.jmedchem.6b00954
  183. Yang, Q.; Wu, L.; Li, L.; Zhou, Z.; Huang, Y. Subcellular co-delivery of two different site-oriented payloads for tumor therapy. Nanoscale, 2017, 9(4), 1547–1558. doi: 10.1039/c6nr08200a
  184. Shirure, V.S.; George, S.C. Design considerations to minimize the impact of drug absorption in polymer-based organ-on-a-chip platforms. Lab on a Chip, 2017, 17(4), 681–690. doi: 10.1039/c6lc01401a
  185. Bus, T.; Englert, C.; Reifarth, M.; Borchers, P.; Hartlieb, M.; Vollrath, A.; Hoeppener, S.; Traeger, A.; Schubert, U.S. 3rd generation poly(ethylene imine)s for gene delivery. Journal of Materials Chemistry B, 2017, 5(6), 1258–1274. doi: 10.1039/C6TB02592G
  186. Wang, H.; Wu, J.; Xu, L.; Xie, K.; Chen, C.; Dong, Y. Albumin Nanoparticle Encapsulation of Potent Cytotoxic Therapeutics Shows Sustained Drug Release and Alleviates Cancer Drug Toxicity. Chemical Communications, 2017, 53(17), 2618–2621. doi: 10.1039/c6cc08978j
  187. Lu, K.-Y.; Li, R.; Hsu, C.-H.; Lin, C.-W.; Chou, S.-C.; Tsai, M.-L.; Mi, F.-L. Development of a new type of multifunctional fucoidan-based nanoparticles for anticancer drug delivery. Carbohydrate Polymers, 2017, 165, 410–420. doi: 10.1016/j.carbpol.2017.02.065
  188. Cheng, L.; Ji, K.; Shih, T. Y.; Haddad, A.; Giatsidis, G.; Mooney, D.J.; Orgill, D.P.; Nabzdyk, C.S. Injectable Shape-Memorizing Three-Dimensional Hyaluronic Acid Cryogels for Skin Sculpting and Soft Tissue Reconstruction. Tissue Engineering Part A, 2017, 23(5–6), 243–251. doi: 10.1089/ten.tea.2016.0263
  189. Kilic, E.; Novoselova, M.V.; Lim, S.H.; Pyataev, N.A.; Pinyaev, S.I.; Kulikov, O.A.; Sindeeva, O.A.; Mayorova, O.A.; Murney, R.; Antipina, M.N.; Haigh, B.; Sukhorukov, G.B.; Kiryukhin, M.V. Formulation for Oral Delivery of Lactoferrin Based on Bovine Serum Albumin and Tannic Acid Multilayer Microcapsules. Scientific Reports, 2017, 7, 44159. doi: 10.1038/srep44159
  190. Musiol-Kroll, E.M.; Zubeil, F.; Schafhauser, T.; Härtner, T.; Kulik, A.; McArthur, J.B.; Koryakina, I.; Wohlleben, W.; Grond, S.; Williams, G.J.; Lee, S.Y.; Weber, T. Polyketide bio-derivatization using the promiscuous acyltransferase KirCII. ACS Synthetic Biology, 2017, 6(3), 421–427. doi: 10.1021/acssynbio.6b00341
  191. Shi, F.; Li, M.; Wu, S.; Yang, F.; Di, W.; Pan, M.; Zhao, F.; Luo, S.; Gu, N.; Dou, J. Enhancing the Anti-Multiple Myeloma Efficiency in a Cancer Stem Cell Xenograft Model by Conjugating the ABCG2 Antibody with Microbubbles for a Targeted Delivery of Ultrasound Mediated Epirubicin. Biochemical Pharmacology, 2017, 132, 18–28. doi: 10.1016/j.bcp.2017.02.014
  192. Taneja, N.; Zofall, M.; Balachandran, V.; Thillainadesan, G.; Sugiyama, T.; Wheeler, D.; Zhou, M.; Grewal, S.I.S. SNF2 Family Protein Fft3 Suppresses Nucleosome Turnover to Promote Epigenetic Inheritance and Proper Replication. Molecular Cell, 2017, 66(1), 50–62. doi: 10.1016/j.molcel.2017.02.006
  193. Lin, S.; Shah, A.; Hernández-Gil, J.; Stanziola, A.; Harriss, B.I.; Matsunaga, T.O.; Long, N.; Bamber, J.; Tang, M.-X. Optically and acoustically triggerable sub-micron phase-change contrast agents for enhanced photoacoustic and ultrasound imaging. Photoacoustics, 2017, 6, 26–36. doi: 10.1016/j.pacs.2017.04.001
  194. Kaux JF, Libertiaux V, Leprince P, Fillet M, Denoel V Wyss C, Lecut C, Gothot A, Le Goff C, Croisier JL, Crielaard JM, Drion P. Eccentric Training for Tendon Healing After Acute Lesion: A Rat Model. The American Journal of Sports Medicine, 2017, 45(6), 1440–1446. doi: 10.1177/0363546517689872
  195. Lunde, N.N.; Haugen, M.H.; Larsen, K.B.B.; Damgaard, I.; Pettersen, S.J.; Kasem, R.; Rut, W.; Drag, M.; Poreba, M.; Johansen, Harald T.; Solberg, R. Glycosylation is important for legumain localization and processing to active forms but not for cystatin E/M inhibitory functions. Biochimie, 2017, 139, 27–37. doi: 10.1016/j.biochi.2017.05.009
  196. Schlegel, I.; Muñoz-Espí, R.; Renz, P.; Lieberwirth, I.; Floudas, G.; Suzuki, Y.; Crespy, D.; Landfester, K. Crystallinity Tunes Permeability of Polymer Nanocapsules. Macromolecules, 2017, 50(12), 4725–4732. doi: 10.1021/acs.macromol.7b00667
  197. Shalgunov, V.; Zaytseva-Zotova, D.; Zinchenko, A.; Levada, T.; Shilov, Y.; Andreyev, D.; Dzhumashev, D.; Metelkin, E.; Urusova, A.; Demin, O.; McDonnell, K.; Troiano, G.; Zale, S.; Safarovа, E. Comprehensive study of the drug delivery properties of poly(L-lactide)-poly(ethylene glycol) nanoparticles in rats and tumor-bearing mice. Journal of Controlled Release, 2017, 261, 31–42. doi: 10.1016/j.jconrel.2017.06.006
  198. Maity, S.; Viazovkina, E.; Gall, A.; Lyubchenko, Y.L. Single-molecule probing of amyloid nano-ensembles using the polymer nanoarray approach. Physical Chemistry Chemical Physics, 2017, 19(25), 16387–16394. doi: 10.1039/c7cp02691a
  199. Nakhaei, E.; Kim, C.W.; Funamoto, D.; Sato, H.; Nakamura, Y.; Kishimura, A.; Mori, T.; Katayama, Y. Design of a ligand for cancer imaging with long blood circulation and an enhanced accumulation ability in tumors. MedChemComm, 2017, 8(6), 1190–1195. doi: 10.1039/c7md00102a
  200. Beldman, T.J.; Senders, M.L.; Alaarg, A.; Perez-Medina, C.; Tang, J.; Zhao, Y.; Fay, F.; Deichmöller, J.; Born, B.; Desclos, E.; van der Wel, N.N.; Hoebe, R.A.; Kohen, F.; Kartvelishvily, E.; Neeman, M.; Reiner, T.; Calcagno, C.; Fayad, Z.A.; de Winther, M.P.J.; Lutgens, E.; Mulder, W.J.M.; Kluza, E. Hyaluronan Nanoparticles Selectively Target Plaque-Associated Macrophages and Improve Plaque Stability in Atherosclerosis. ACS Nano, 2017, 11(6), 5785–5799. doi: 10.1021/acsnano.7b01385
  201. Luthman, A.S.; Dumitru, S.; Quiros-Gonzalez, I.; Joseph, J.; Bohndiek, S.E. Fluorescence hyperspectral imaging (fHSI) using a spectrally resolved detector array. Journal of Biophotonics, 2017, 10(6–7), 840–853. doi: 10.1002/jbio.201600304
  202. Massey, M.; Kim, H.; Conroy, E.M.; Algar, W.R. Expanded Quantum Dot-Based Concentric Förster Resonance Energy Transfer: Adding and Characterizing Energy-Transfer Pathways for Triply Multiplexed Biosensing. The Journal of Physical Chemistry C, 2017, 121(24), 13345–13356. doi: 10.1021/acs.jpcc.7b02739
  203. Zhao, T.; Li, T.; Liu, Y. Silver nanoparticle plasmonic enhanced förster resonance energy transfer (FRET) imaging of protein-specific sialylation on the cell surface. Nanoscale, 2017, 9(28), 9841–9847. doi: 10.1039/c7nr01562c
  204. Warminski, M.; Sikorski, P.J.; Warminska, Z.; Lukaszewicz, M.; Kropiwnicka, A.; Zuberek, J.; Darzynkiewicz, E.; Kowalska, J.; Jemielity, J. Amino-functionalized 5' cap analogs as tools for site-specific sequence-independent labeling of messenger RNA. Bioconjugate Chemistry, 2017, 28(7), 1978–1992. doi: 10.1021/acs.bioconjchem.7b00291
  205. Garg, S.M.; Paiva, I.M.; Vakili, M.R.; Soudy, R.; Agopsowicz, K.; Soleimani, A.; Hitt, M.; Kaur, K.; Lavasanifar, A. Traceable PEO-poly(ester) micelles for breast cancer targeting: The effect of core structure and targeting peptide on micellar tumor accumulation. Biomaterials, 2017, 144, 17–29. doi: 10.1016/j.biomaterials.2017.08.001
  206. Zhou, Z.; Liu, Y.; Wu, L.; Li, L.; Huang, Y. Enhanced nuclear delivery of anti-cancer drugs using micelles containing releasable membrane fusion peptide and nuclear-targeting retinoic acid. Journal of Materials Chemistry B, 2017, 5(34), 7175–7185. doi: 10.1039/C7TB01177F
  207. Drexel, M.; Romanov, R.A.; Wood, J.; Weger, S.; Heilbronn, R.; Wulff, P.; Tasan, R.O.; Harkany, T.; Sperk, G. Selective silencing of hippocampal parvalbumin interneurons induces development of recurrent spontaneous limbic seizures in mice. Journal of Neuroscience, 2017, 37(34), 8166–8179. doi: 10.1523/jneurosci.3456-16.2017
  208. Stefanello, T.; Couturaud, B.; Szarpak, A.; Fournier, D.; Louage, B.; Garcia, F.; Vataru Nakamura, C.; De Geest, B.; Woisel, P.; van der Sanden, B.; Auzely, R. Coumarin-containing thermoresponsive hyaluronic acid-based nanogels as delivery systems for anticancer chemotherapy. Nanoscale, 2017, 9(33), 12150–12162. doi: 10.1039/C7NR03964F
  209. Long, M.J.; Lin, H.-Y.; Parvez, S.; Zhao, Y.; Poganik, J.R.; Huang, P.; Aye, Y. β-TrCP1 Is a Vacillatory Regulator of Wnt Signaling. Cell Chemical Biology, 2017, 24(8), 944–957.e7. doi: 10.1016/j.chembiol.2017.06.009
  210. Westergaard Mulberg, M.; Taskova, M.; Thomsen, R.P.; Okholm, A.H.; Kjems, J.; Astakhova, K. New Fluorescent Nanoparticles for Ultrasensitive Detection of Nucleic Acids by Optical Methods. Chembiochem, 2017, 18(16), 1599–1603. doi: 10.1002/cbic.201700125
  211. Louage, B.; Tack, L.; Wang, Y.; De Geest, B.G. Poly(glycerol sebacate) nanoparticles for encapsulation of hydrophobic anti-cancer drugs. Polymer Chemistry, 2017, 8(34), 5033–5038. doi: 10.1039/c6py02192a
  212. Poh, S.; Putt, K.S.; Low, P.S. Folate-targeted dendrimers selectively accumulate at sites of inflammation in mouse models of ulcerative colitis and atherosclerosis. Biomacromolecules, 2017, 18(10), 3082–3088. doi: 10.1021/acs.biomac.7b00728
  213. Zhao, Y.; Houston, Z.H.; Simpson, J.D.; Chen, L.; Fletcher, N.L.; Fuchs, A.V.; Blakey, I.; Thurecht, K.J. Using Peptide Aptamer Targeted Polymers as a Model Nanomedicine for Investigating Drug Distribution in Cancer Nanotheranostics. Molecular Pharmaceutics, 2017, 14(10), 3539–3549. doi: 10.1021/acs.molpharmaceut.7b00560
  214. Qiu, Y.; Levendosky, R.F.; Chakravarthy, S.; Patel, A.; Bowman, G.D.; Myong, S. The Chd1 Chromatin Remodeler Shifts Nucleosomal DNA Bidirectionally as a Monomer. Molecular Cell, 2017, 68(1), 76–88.e6. doi: 10.1016/j.molcel.2017.08.018
  215. Yang, W.; Xia, Y.; Zou, Y.; Meng, F.; Zhang, J.; Zhong, Z. Bioresponsive Chimaeric Nano-polymersomes Enable Targeted and Efficacious Protein Therapy for Human Lung Cancers in Vivo. Chemistry of Materials, 2017, 29(20), 8757–8765. doi: 10.1021/acs.chemmater.7b02953
  216. Gilbert, T.; Alsop, R.J.; Babi, M.; Moran-Mirabal, J.; Rheinstadter, M.C.; Hoare, T. Nanostructure of Fully Injectable Hydrazone-Thiosuccinimide Interpenetrating Polymer Network Hydrogels Assessed by Small-Angle Neutron Scattering and dSTORM Single-Molecule Fluorescence Microscopy. ACS Applied Materials & Interfaces, 2017, 9(48), 42179–42191. doi: 10.1021/acsami.7b11637
  217. Lin, T.-H.; Lin, C.-H.; Liu, Y.-J.; Huang, C.Y.; Lin, Y.-C.; Wang, S.-K. Controlling Ligand Spacing on Surface: Polyproline-Based Fluorous Microarray as a Tool in Spatial Specificity Analysis and Inhibitor Development for Carbohydrate-Protein Interactions. ACS Applied Materials & Interfaces, 2017, 9(48), 41691–41699. doi: 10.1021/acsami.7b13200
  218. Masarapu, H.; Patel, B.K.; Chariou, P.L.; Hu, H.; Gulati, N.M.; Carpenter, B.L.; Ghiladi, R.A.; Shukla, S.; Steinmetz, N.F. Physalis Mottle Virus-Like Particles as Nanocarriers for Imaging Reagents and Drugs. Biomacromolecules, 2017, 18(12), 4141–4153. doi: 10.1021/acs.biomac.7b01196
  219. Butler, C.R.; Beck, E.M.; Harris, A.R.; Huang, Z.; McAllister, L.A.; Am Ende, C.W.; Fennell, K.F.; Foley, T.L.; Fonseca, K.R.; Hawrylik, S.J.; Johnson, D.S.; Knafels, J.D.; Mente, S.; Noell, S.; Pandit, J.; Phillips, T.B.; Piro, J.R.; Rogers, B.N.; Samad, T.A.; Wang, J.; Wan, S.; Brodney, M.A. Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase. Journal of Medicinal Chemistry, 2017, 60(23), 9860–9873. doi: 10.1021/acs.jmedchem.7b01531
  220. Cao, T.; Zhou, X.; Zheng, Y.; Sun, Y.; Zhang, J.; Chen, W.; Zhang, J.; Zhou, Z.; Yang, S.-P.; Zhang, Y.; Yang, H.; Wang, M.-W. Chelator-Free Conjugation of 99mTc and Gd3+ to PEGylated Nanographene Oxide for Dual-modality SPECT/MR Imaging of Lymph Nodes. ACS Applied Materials & Interfaces, 2017, 9(49), 42612–42621. doi: 10.1021/acsami.7b14836
  221. Barsh, G.R.; Isabella, A.J.; Moens, C.B. Vagus Motor Neuron Topographic Map Determined by Parallel Mechanisms of hox5 Expression and Time of Axon Initiation. Current Biology, 2017, 27(24), 3812–3825.e3. doi: 10.1016/j.cub.2017.11.022
  222. Wei, L.; Chen, Z.; Shi, L.; Long, R.; Anzalone, A.V.; Zhang, L.; Hu, F.; Yuste, R.; Cornish, V.W.; Min, W. Super-multiplex vibrational imaging. Nature, 2017, 544(7651), 465-470. doi: 10.1038/nature22051

2016

  1. Löschmann, N.; Michaelis, M.; Rothweiler, F.; Voges, Y.; Balónová, B.; Blight, B.A.; Cinatl, J. ABCB1 as predominant resistance mechanism in cells with acquired SNS-032 resistance. Oncotarget, 2016, 7(36), 58051–58064. doi: 10.18632/oncotarget.11160
  2. Korkmaz, E.; Friedrich, E.E.; Ramadan, M.H.; Erdos, G.; Mathers, A.R.; Ozdoganlar, O.B.; Washburn, N.R.; Falo, Jr, L.D. Tip-Loaded Dissolvable Microneedle Arrays Effectively Deliver Polymer-Conjugated Antibody Inhibitors of Tumor-Necrosis-Factor-Alpha Into Human Skin. Journal of Pharmaceutical Sciences, 2016, 105(11), 3453–3457. doi: 10.1016/j.xphs.2016.07.008
  3. Jackson, A.; Jani, S.; Sala, C.D.; Soler-Bistué, A.J.C.; Zorreguieta, A.; Tolmasky, M.E. Assessment of configurations and chemistries of bridged nucleic acids-containing oligomers as external guide sequences: a methodology for inhibition of expression of antibiotic resistance genes. Biology Methods and Protocols, 2016, 1(1), bpw001. doi: 10.1093/biomethods/bpw001
  4. Yoshimura, T.; Kurogi, K.; Liu, M.-C.; Suiko, M.; Sakakibara, Y. A proteomic approach for the analysis of S-nitrosylated proteins using a fluorescence labeling technique. Journal of Electrophoresis, 2016, 60(1), 5–14. doi: 10.2198/jelectroph.60.5
  5. Rudnick-Glick, S.; Corem-Salkmon, E.; Grinberg, I.; Margel, S. Targeted drug delivery of near IR fluorescent doxorubicin-conjugated poly(ethylene glycol) bisphosphonate nanoparticles for diagnosis and therapy of primary and metastatic bone cancer in a mouse model. Journal of Nanobiotechnology, 2016, 14, 80. doi: 10.1186/s12951-016-0233-6
  6. Mendler, C.T.; Feuchtinger, A.; Heid, I.; Aichler, M.; D'Alessandria, C.; Pirsig, S.; Blechert, B.; Wester, H.-J.; Braren, R.; Walch, A.; Skerra, A.; Schwaiger, M. Tumor uptake of anti-CD20 Fabs depends on tumor perfusion. Journal of Nuclear Medicine, 2016, 57(12), 1971–1977. doi: 10.2967/jnumed.116.176784
  7. Nemethova, M.; Talian, I.; Danielisova, V.; Tkacikova, S.; Bonova, P.; Bober, P.; Matiasova, M.; Sabo, J.; Burda, J. Delayed bradykinin postconditioning modulates intrinsic neuroprotective enzyme expression in the rat CA1 region after cerebral ischemia: a proteomic study. Metabolic Brain Disease, 2016, 31(6), 1391–1403. doi: 10.1007/s11011-016-9859-1
  8. Li, Y.; Zhao, Q.; Wang, Y.; Man, T.; Zhou, L.; Fang, X.; Pei, H.; Chi, L.; Liu, J. Ultrasensitive Signal-on Detection of Nucleic Acids with Surface-Enhanced Raman Scattering and Exonuclease III Assisted Probe Amplification. Analytical Chemistry, 2016, 88(23), 11684–11690. doi: 10.1021/acs.analchem.6b03267
  9. Wu, Z.-G.; Jiang, W.; Chen, S.-L.; Mantri, N.; Tao, Z.-M.; Jiang, C.-X. Insights from the Cold Transcriptome and Metabolome of Dendrobium officinale: Global Reprogramming of Metabolic and Gene Regulation Networks during Cold Acclimation. Frontiers in Plant Science, 2016, 7, 1653. doi: 10.3389/fpls.2016.01653
  10. Zhang, X.; MIn, L.; Jia, C. Application of Wavelet Transform Algorithm and Rolling Ball Algorithm in Single Molecule Fluorescence Resonance Energy Transfer Images. Progress in Biochemistry and Biophysics, 2016, 43(10), 997–1003. doi: 10.16476/j.pibb.2016.0218
  11. Ruhl, K.E; Rovis, T. Visible Light-Gated Cobalt Catalysis for a Spatially and Temporally Resolved [2+2+2] Cycloaddition. Journal of the American Chemical Society, 2016, 138(48), 15527–15530. doi: 10.1021/jacs.6b08792
  12. Koziolová, E.; Machová, D.; Pola, R.; Janoušková, O.; Chytil, P.; Laga, R.; Filippov, S.K.; Šubr, V.; Etrych, T.; Pechar, M. Micelle-forming HPMA copolymer conjugates of ritonavir bound via a pH-sensitive spacer with improved cellular uptake designed for enhanced tumor accumulation. Journal of Materials Chemistry B, 2016, 4(47), 7620–7629. doi: 10.1039/C6TB02225A
  13. Zhou, L.; Wang, K.; Wu, Z.; Dong, H.; Sun, H.; Cheng, X.; Zhang, H.; Zhou, H.; Jia, C.; Jin, Q.; Mao, H.; Coll, J.-L.; Zhao, J. Investigation of Controllable Nanoscale Heat-Denatured Bovine Serum Albumin Films on Graphene. Langmuir, 2016, 32(48), 12623–12631. doi: 10.1021/acs.langmuir.6b03296
  14. Xu, X.; Xu, Z.; Liu, J.; Zhang, Z.; Chen, H.; Li, X.; Shi, S. Visual tracing of diffusion and biodistribution for amphiphilic cationic nanoparticles using photoacoustic imaging after ex vivo intravitreal injections. International Journal of Nanomedicine, 2016, 11, 5079–5086. doi: 10.2147/IJN.S109986
  15. Yan, Y.; Liu, L.; Xiong, H.; Miller, J.B.; Zhou, K.; Kos, P.; Huffman, K.E.; Elkassih, S.; Norman, J.W.; Carstens, R.; Kim, J.; Minna, J.D.; Siegwart, D.J. Functional polyesters enable selective siRNA delivery to lung cancer over matched normal cells. Proceedings of the National Academy of Sciences of the U.S.A., 2016, 113(39), E5702–E5710. doi: 10.1073/pnas.1606886113
  16. Xue, C.; Whitis, N.R.; Sashital, D.G. Conformational Control of Cascade Interference and Priming Activities in CRISPR Immunity. Molecular Cell, 2016, 64(4), 826–834. doi: 10.1016/j.molcel.2016.09.033
  17. Duan, X.; Li, H.; Zhou, J.; Zhou, Q.; Oldham, K.R.; Wang, T.D. Visualizing epithelial expression of EGFR in vivo with distal scanning side-viewing confocal endomicroscope. Scientific Reports, 2016, 6, 37315. doi: 10.1038/srep37315
  18. Cheng, J.; Feng, S.; Han, S.; Zhang, X.; Chen, Y.; Zhou, X.; Wang, R.; Li, X.; Hu, H.; Zhang, J. Facile Assembly of Cost-Effective and Locally Applicable or Injectable Nanohemostats for Hemorrhage Control. ACS Nano, 2016, 10(11), 9957&ndash9973. doi: 10.1021/acsnano.6b04124
  19. Allen, C.D.; Chen, M.Y.; Trick, A.Y.; Le, D.T.; Ferguson, A.L.; Link, A.J. Thermal Unthreading of the Lasso Peptides Astexin-2 and Astexin-3. ACS Chemical Biology, 2016, 11(11), 3043–3051. doi: 10.1021/acschembio.6b00588
  20. Ye, R.; Zhu, C.; Song, Y.; Song, J.; Fu, S.; Lu, Q.; Yang, X.; Zhu, M.-J.; Du, D.; Li, H.; Lin, Y. One-pot bioinspired synthesis of all-inclusive protein–protein nanoflowers for point-of-care bioassay: detection of E. coli O157:H7 from milk. Nanoscale, 2016, 8(45), 18980–18986. doi: 10.1039/c6nr06870g
  21. Mattheolabakis, G.; Ling, D.; Ahmad, G.; Amiji, M. Enhanced Anti-Tumor Efficacy of Lipid-Modified Platinum Derivatives in Combination with Survivin Silencing siRNA in Resistant Non-Small Cell Lung Cancer. Pharmaceutical Research, 2016, 33(12), 2943–2953. doi: 10.1007/s11095-016-2016-z
  22. Cai, Lei and Dewi, Ruby E. and Goldstone, Andrew B. and Cohen, Jeffrey E. and Steele, Amanda N. and Woo, Y. Joseph and Heilshorn, Sarah C. Regulating Stem Cell Secretome Using Injectable Hydrogels with In Situ Network Formation. Advanced Healthcare Materials, 2016, 5(21), 2758–2764. doi: 10.1002/adhm.201600497
  23. Nemudraya, A.; Kuligina, E.; Ilyichev, A.; Fomin, A.; Stepanov, G.; Savelyeva, A.; Koval, O.; Richter, V. Selection of antitumor displayed peptides for the specific delivery of the anticancer drug lactaptin. Oncology Letters, 2016, 12(6), 4547–4555. doi: 10.3892/ol.2016.5266
  24. Parvez, S.; Long, M.J.C.; Lin, H.-Y.; Zhao, Y.; Haegele, J.A.; Pham, V.N.; Lee, D.K.; Aye, Y. T-REX on-demand redox targeting in live cells. Nature Protocols, 2016, 11(12), 2328–2356. doi: 10.1038/nprot.2016.114
  25. Berte, N.; Piee-Staffa, A.; Piecha, N.; Wang, M.; Borgmann, K.; Kaina, B.; Nikolova, T. Targeting homologous recombination by pharmacological inhibitors enhances the killing response of glioblastoma cells treated with alkylating drugs. Molecular Cancer Therapeutics, 2016, 15(11), 2665–2678. doi: 10.1158/1535-7163.mct-16-0176
  26. Hill, T.K.; Kelkar, S.S.; Wojtynek, N.E.; Souchek, J.J:; Payne, W.M.; Stumpf, K.; Marini, F.C.; Mohs, A.M. Near Infrared Fluorescent Nanoparticles Derived from Hyaluronic Acid Improve Tumor Contrast for Image-Guided Surgery. Theranostics, 2016, 6(13), 2314–2328. doi: 10.7150/thno.16514
  27. Cao, T.; You, P.; Zhou, X.; Luo, J.; Xu, X.; Zhou, Z.; Yang, S.; Zhang, Y.; Yang, H.; Wang, M. Visualization of size-dependent tumour retention of PEGylated nanographene oxide via SPECT imaging. Journal of Materials Chemistry B, 2016, 4(39), 6446–6453. doi: 10.1039/c6tb01892k
  28. Machulkin, A.E.; Garanina, A.S.; Zhironkina, O.A.; Beloglazkina, E.K.; Zyk, N.V.; Savchenko, A.G.; Kotelyanskii, V.E.; Mazhuga, A.G. Nanohybride Materials Based on Magnetite-Gold Nanoparticles for Diagnostics of Prostate Cancer: Synthesis and In Vitro Testing. Bulletin of Experimental Biology and Medicine, 2016, 161(5), 706–710. doi: 10.1007/s10517-016-3490-3
  29. Chen, W.; Wang, F.; Zhang, X.; Hu, J.; Wang, X.; Yang, K.; Huang, L.; Xu, M.; Li, Q.; Fu, L. Overcoming ABCG2-mediated multidrug resistance by a mineralized hyaluronan-drug nanocomplex. Journal of Materials Chemistry B, 2016, 4(41), 6652–6661. doi: 10.1039/c6tb01545j
  30. Zuhl, A.M.; Nolan, C.E.; Brodney, M.A.; Niessen, S.; Atchison, K.; Houle, C.; Karanian, D.A.; Ambroise, Cl.; Brulet, J.W.; Beck, E.M.; Doran, S.D.; O'Neill, B.T.; am Ende, C.W.; Chang, C.; Geoghegan, K.F.; West, G.M.; Judkins, J.C.; Hou, X.; Riddell, D.R.; Johnson, D.S. Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of β-secretase inhibitors. Nature communications, 2016, 7, 13042. doi: 10.1038/ncomms13042
  31. Pombo-García, K.; Weiss, S.; Zarschler, K.; Ang, C.-S.; Hübner, R.; Pufe, J.; Meister, S.; Seidel, J.; Pietzsch, J.; Spiccia, L.; Stephan, H.; Graham, B. Zwitterionic polymer-coated ultrasmall superparamagnetic iron oxide nanoparticles with low protein interaction and high biocompatibility. ChemNanoMat, 2016, 2(10), 959–971. doi: 10.1002/cnma.201600233
  32. Shi, P.; Ju, E.; Yan, Z.; Gao, N.; Wang, J.; Hou, J.; Zhang, Y.; Ren, J.; Qu, X. Spatiotemporal control of cell-cell reversible interactions using molecular engineering. Nature communications, 2016, 7, 13088. doi: 10.1038/ncomms13088
  33. Zhou, Q.; Li, Z.; Zhou, J.; Joshi, B.P.; Li, G.; Duan, X.; Kuick, R.; Owens, S.R.; Wang, T.D. In vivo photoacoustic tomography of EGFR overexpressed in hepatocellular carcinoma mouse xenograft. Photoacoustics, 2016, 4(2), 43–54. doi: 10.1016/j.pacs.2016.04.001
  34. Mann, S.K.; Dufour, A.; Glass, J.J.; De Rose, R.; Kent, S.J.; Such, G.K.; Johnston, A.P.R. Tuning the properties of pH responsive nanoparticles to control cellular interactions in vitro and ex vivo. Polymer Chemistry, 2016, 7(38), 6015–6024. doi: 10.1039/c6py01332e
  35. Ye, Y.; Wang, J.; Hu, Q.; Hochu, G.M.; Xin, H.; Wang, C.; Gu, Z. Synergistic Transcutaneous Immunotherapy Enhances Antitumor Immune Responses through Delivery of Checkpoint Inhibitors. ACS Nano, 2016, 10(9), 8956–8963. doi: 10.1021/acsnano.6b04989
  36. Gera, L.; Charest-Morin, X.; Jean, M.; Bachelard, H.; Marceau, F. Infrared-emitting, peptidase-resistant fluorescent ligands of the bradykinin B2 receptor: application to cytofluorometry and imaging. BMC Research Notes, 2016, 9, 452. doi: 10.1186/s13104-016-2258-1
  37. Smith, A.A.A.; Zuwala, K.; Pilgram, O.; Johansen, K.S.; Tolstrup, M.; Dagnæs-Hansen, F.; Zelikin, A.N. Albumin-Polymer-Drug Conjugates: Long Circulating, High Payload Drug Delivery Vehicles. ACS Macro Letters, 2016, 5, 1089–1094. doi: 10.1021/acsmacrolett.6b00544
  38. Zhao, L.; Ma, S.; Pan, Y.; Zhang, Q.; Wang, K.; Song, D.; Wang, X.; Feng, G.; Liu, R.; Xu, H.; Zhang, J.; Qiao, M.; Kong, D. Functional Modification of Fibrous PCL Scaffolds with Fusion Protein VEGF-HGFI Enhanced Cellularization and Vascularization. Advanced Healthcare Materials, 2016, 5(18), 2376–2385. doi: 10.1002/adhm.201600226
  39. Xiao, F.; Li, G.; Wu, Y.; Chen, Q.; Wu, Z.; Yu, R. Label-Free Photonic Crystal-Based β-Lactamase Biosensor for β-Lactam Antibiotic and β-Lactamase Inhibitor. Analytical Chemistry, 2016, 88(18), 9207–9212. doi: 10.1021/acs.analchem.6b02457
  40. Sui, B.; Zhong, G.; Sun, J. Drug-loadable Mesoporous Bioactive Glass Nanospheres: Biodistribution, Clearance, BRL Cellular Location and Systemic Risk Assessment via 45Ca Labelling and Histological Analysis. Scientific Reports, 2016, 6, 33443. doi: 10.1038/srep33443
  41. Fiacco, S.V.; Kelderhouse, L.E.; Hardy, A.; Peleg, Y.; Hu, B.; Ornelas, A.; Yang, P.; Gammon, S.T.; Howell, S.M.; Wang, P.; Takahashi, T.T.; Millward, S.W.; Roberts, R.W. Directed Evolution of Scanning Unnatural-Protease-Resistant (SUPR) Peptides for in Vivo Applications. Chembiochem, 2016, 17(17), 1643–1651. doi: 10.1002/cbic.201600253
  42. Liu, M.; Richardson, R.R.; Mountford, S.J.; Zhang, L.; Tempone, M.H.; Herzog, H.; Holliday, N.D.; Thompson, P.E. Identification of a Cyanine-Dye Labelled Peptidic Ligand for Y1R and Y4R, based upon the Neuropeptide Y C-terminal analogue, BVD-15. Bioconjugate Chemistry, 2016, 27(9), 2166–2175. doi: 10.1021/acs.bioconjchem.6b00376
  43. Ramirez, Lisa and Herschkowitz, Jason I. and Wang, Jun. Stand-Sit Microchip for High-Throughput, Multiplexed Analysis of Single Cancer Cells. Scientific Reports, 2016, 6, 32505. doi: 10.1038/srep32505
  44. Liu, S.; Dozois, M.D.; Chang, C.N.; Ahmad, A.; Ng, D.L.T.; Hileeto, D.; Liang, H.; Reyad, M.-M.; Boyd, S.; Jones, L.W.; Gu, F.X. Prolonged Ocular Retention of Mucoadhesive Nanoparticle Eye Drop Formulation Enables Treatment of Eye Diseases Using Significantly Reduced Dosage. Molecular Pharmaceutics, 2016, 13(9), 2897–2905. doi: 10.1021/acs.molpharmaceut.6b00445
  45. Mann, S.K.; Czuba, E.; Selby, L.I.; Such, G.K.; Johnston, A.P.R. Quantifying Nanoparticle Internalization Using a High Throughput Internalization Assay. Pharmaceutical Research, 2016, 33(10), 2421–2432. doi: 10.1007/s11095-016-1984-3
  46. Hong, W.; Lee, S.; Chang, H.J.; Lee, E.S.; Cho, Y. Multifunctional magnetic nanowires: A novel breakthrough for ultrasensitive detection and isolation of rare cancer cells from non-metastatic early breast cancer patients using small volumes of blood. Biomaterials, 2016, 106, 78–86. doi: 10.1016/j.biomaterials.2016.08.020
  47. Chen, Y.; Li, Y.; Shen, W.; Li, K.; Yu, L.; Chen, Q.; Ding, J. Controlled release of liraglutide using thermogelling polymers in treatment of diabetes. Scientific Reports, 2016, 6, 31593. doi: 10.1038/srep31593
  48. Kollarigowda, R.H.; De Santo, I.; Rianna, C.; Fedele, C.; Manikas, A.C.; Cavalli, S.; Netti, P.A. Shedding light on azopolymer brush dynamics by fluorescence correlation spectroscopy. Soft Matter, 2016, 12(34), 7102–7111. doi: 10.1039/c6sm01482h
  49. Sun, Y.; Hong, S.; Ma, X.; Cheng, K.; Wang, J.; Zhang, Z.; Yang, M.; Jiang, Y.; Hong, X.; Cheng, Z. Recyclable Cu(I)/Melanin Dots for Cycloadditions, Bioconjugation and Cell Labeling. Chemical Science, 2016, 7(9), 5888–5892. doi: 10.1039/c6sc01536k
  50. Zhang, Q.; Tao, H.; Lin, Y.; Hu, Y.; An, H.; Zhang, D.; Feng, S.; Hu, H.; Wang, R.; Li, X.; Zhang, J. A superoxide dismutase/catalase mimetic nanomedicine for targeted therapy of inflammatory bowel disease. Biomaterials, 2016, 105, 206–221. doi: 10.1016/j.biomaterials.2016.08.010
  51. Feng, S.; Hu, Y.; Peng, S.; Han, S.; Tao, H.; Zhang, Q.; Xu, X.; Zhang, J.; Hu, H. Nanoparticles responsive to the inflammatory microenvironment for targeted treatment of arterial restenosis. Biomaterials, 2016, 105, 167–184. doi: 10.1016/j.biomaterials.2016.08.003
  52. Spears, B.R.; Marin, M.A.; Chaker, A.N.; Lampley, M.W.; Harth, E. Precise Microscale Polymeric Networks through Piezoelectronic Inkjet Printing. ACS Biomaterials Science & Engineering, 2016, 2(8), 1265–1272. doi: 10.1021/acsbiomaterials.6b00175
  53. Su, S.; Wang, J.; Vargas, E.; Wei, J.; Martinez-Zaguilan, R.; Sennoune, S.R.; Pantoya, M.L.; Wang, S.; Chaudhuri, J.; Qiu, J. Porphyrin Immobilized Nano-Graphene Oxide for Enhanced and Targeted Photothermal Therapy of Brain Cancer. ACS Biomaterials Science & Engineering, 2016, 2(8), 1357–1366. doi: 10.1021/acsbiomaterials.6b00290
  54. Li, Hong-Jun and Du, Jin-Zhi and Liu, Jing and Du, Xiao-Jiao and Shen, Song and Zhu, Yan-Hua and Wang, Xiaoyan and Ye, Xiaodong and Nie, Shuming and Wang, Jun. Smart Superstructures with Ultrahigh pH-Sensitivity for Targeting Acidic Tumor Microenvironment: Instantaneous Size Switching and Improved Tumor Penetration. ACS Nano, 2016, 10(7), 6753–6761. doi: 10.1021/acsnano.6b02326
  55. Jiang, X.; Bugno, J.; Hu, C.; Yang, Y.; Herold, T.; Qi, J.; Chen, P.; Gurbuxani, S.; Arnovitz, S.; Strong, J.; Ferchen, K.; Ulrich, B.; Weng, H.; Wang, Y.; Huang, H.; Li, S.; Neilly, M.B.; Larson, R.A.; Le Beau, M.M.; Bohlander, S.K.; Jin, J.; Li, Z.; Bradner, J.E.; Hong, S.; Chen, J. Eradication of acute myeloid leukemia with FLT3 ligand-targeted miR-150 nanoparticles. Cancer Research, 2016, 76(15), 4470–4480. doi: 10.1158/0008-5472.CAN-15-2949
  56. Tsai, C.-Y.; Li, C.-W.; Li, J.-R.; Jang, B.-H.; Chen, S.-H. Steroid Probes Conjugated with Protein-Protected Gold Nanocluster: Specific and Rapid Fluorescence Imaging of Steroid Receptors in Target Cells. Journal of Fluorescence, 2016, 26(4), 1239–1248. doi: 10.1007/s10895-016-1811-6
  57. Priwitaningrum, D.L.; Blonde, J.-B.; van Baarlen, J.; Hennink, W.E.; Storm, G.; Le Gac, S.; Prakash, J. Tumor stroma-containing 3D spheroid arrays: A tool to study nanoparticle penetration. Journal of Controlled Release, 2016, 244(Part B), 257–268. doi: 10.1016/j.jconrel.2016.09.004
  58. Zhu, Y.; Wang, X.; Chen, J.; Zhang, J.; Meng, F.; Deng, C.; Cheng, R.; Feijen, J.; Zhong, Z. Bioresponsive and fluorescent hyaluronic acid-iodixanol nanogels for targeted X-ray computed tomography imaging and chemotherapy of breast tumors. Journal of controlled release, 2016, 244(Part B), 229–239. doi: 10.1016/j.jconrel.2016.08.027
  59. Zhang, L.; Navaratna, T.; Thurber, G.M. A Helix-Stabilizing Linker Improves Subcutaneous Bioavailability of a Helical Peptide Independent of Linker Lipophilicity , 2016, 27(7), 1663–1672. doi: 10.1021/acs.bioconjchem.6b00209
  60. Wang, C.; Wang, X.; Dong, K.; Luo, J.; Zhang, Q.; Cheng, Y. Injectable and Responsively Degradable Hydrogel for Personalized Photothermal Therapy. Biomaterials, 2016, 104, 129–137. doi: 10.1016/j.biomaterials.2016.07.013
  61. Lu, X.; Jia, F.; Tan, X.; Wang, D.; Cao, X.; Zheng, J.; Zhang, K. Effective Antisense Gene Regulation via Noncationic, Polyethylene Glycol Brushes. Journal of the American Chemical Society, 2016, 138(29), 9097–9100. doi: 10.1021/jacs.6b05787
  62. Wang, C.; Tang, F.; Wang, X.; Li, L. Synthesis and application of biocompatible gold core-poly-(L-Lysine) shell nanoparticles. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2016, 506, 425–430. doi: 10.1016/j.colsurfa.2016.07.014
  63. Zhang, Y.; Li, Z.; Zhang, K.; Yang, G.; Wang, Z.; Zhao, J.; Hu, R.; Feng, N. Ethyl oleate-containing nanostructured lipid carriers improve oral bioavailability of trans-ferulic acid ascompared with conventional solid lipid nanoparticles. International Journal of Pharmaceutics, 2016, 511(1), 57–64. doi: 10.1016/j.ijpharm.2016.06.131
  64. Farzan, V.M.; Aparin, I.O.; Veselova, O.A.; Podkolzin, A.T.; Shipulin, G.A.; Korshun, V.A.; Zatsepin, T.S. Cy5/BHQ dye-quencher pairs in fluorogenic qPCR probes: effects of charge and hydrophobicity. Analytical Methods, 2016, 8(29), 5826–5831. doi: 10.1039/c6ay01304j
  65. Melle, A.; Balaceanu, A.; Kather, M.; Wu, Y.; Gau, E.; Sun, W.; Huang, X.; Shi, X.; Karperien, M.; Pich, A. Stimuli-Responsive Poly(N}-vinylcaprolactam-co-2-methoxyethyl acrylate) Core-Shell Microgels: Facile Synthesis, Modulation of Surface Properties and Controlled Internalisation into Cells. Journal of Materials Chemistry B, 2016, 4(30), 5127–5137. doi: 10.1039/c6tb01196a
  66. Boone, C.; Grove, R.; Adamcova, D.; Braga, C.; Adamec, J. Revealing oxidative damage to enzymes of carbohydrate metabolism in yeast: An integration of 2D DIGE, quantitative proteomics and bioinformatics. Proteomics, 2016, 16(13), 1889–1903. doi: 10.1002/pmic.201500546
  67. Wu, F.; Liu, C.; Chen, Y.; Yang, S.; Xu, J.; Huang, R.; Wang, X.; Li, M.; Liu, W.; Mao, W.; Zhou, X. Visualization of G-quadruplexes in gel and in live cells by a near-infrared fluorescent probe. Sensors and Actuators B: Chemical, 2016, 236, 268–275. doi: 10.1016/j.snb.2016.05.162
  68. Pérez-Medina, C.; Abdel-Atti, D.; Tang, J.; Zhao, Y.; Fayad, Z.A.; Lewis, J.S.; Mulder, W.J.M.; Reiner, T. Nanoreporter PET predicts the efficacy of anti-cancer nanotherapy. Nature Communications, 2016, 7, 11838. doi: 10.1038/ncomms11838
  69. Wilkinson, N.; Metaxas, A.; Ruud, E.; Raethke, E.; Wickramaratne, S.; Reineke, T.M.; Dutcher, C.S. Internal structure visualization of polymer – clay flocculants using fluorescence. Colloids and Interface Science Communications, 2016, 10–11, 1–5. doi: 10.1016/j.colcom.2016.03.002
  70. Wang, H.; Tang, L.; Liu, Y.; Dobrucka, I.T.; Dobrucki, L.W.; Yin, L.; Cheng, J. In Vivo Targeting of Metabolically Labeled Cancers with Ultra-Small Silica Nanoconjugates. Theranostics, 2016, 6(9), 1467–1476. doi: 10.7150/thno.16003
  71. Ngambenjawong, C.; Gustafson, H.H.; Pineda, J.M.; Kacherovsky, N.A.; Cieslewicz, M.; Pun, S.H. Serum Stability and Affinity Optimization of an M2 Macrophage-Targeting Peptide (M2pep). Theranostics, 2016, 6(9), 1403–1414. doi: 10.7150/thno.15394
  72. Chen, K.; Chen, Q.; Wang, K.; Zhu, J.; Li, W.; Li, W.; Qiu, L.; Guan, G.; Qiao, M.; Zhao, X.; Hu, H.; Chen, D. Synthesis and characterization of a PAMAM-OH derivative containing an acid-labile β-thiopropionate bond for gene delivery. International Journal of Pharmaceutics, 2016, 509(1–2), 314–327. doi: 10.1016/j.ijpharm.2016.05.060
  73. Kim, K.-M.; Kim, M.K.; Paek, H.-J.; Choi, S.-J.; Oh, J.-M. Stable fluorescence conjugation of ZnO nanoparticles and their size dependent cellular uptake. Colloids and Surfaces B: Biointerfaces, 2016, 145, 870–877. doi: 10.1016/j.colsurfb.2016.06.006
  74. Samuelsen, S.V.; Maity, A.; Nybo, M.; Macaubas, C.; Lønstrup, L.; Balboni, I.M.; Mellins, E.D.; Astakhova, K. Novel Phospholipid-Protein Conjugates Allow Improved Detection of Antibodies in Patients with Autoimmune Diseases. PLoS One, 2016, 11(6), e0156125. doi: 10.1371/journal.pone.0156125
  75. Huang, R.; Conti, P.S.; Chen, K. In Vivo Tumor Angiogenesis Imaging Using Peptide-Based Near-Infrared Fluorescent Probes. Methods in Molecular Biology, 2016, 1444, 73–84. doi: 10.1007/978-1-4939-3721-9_8
  76. Camerino, M.A.; Liu, M.; Moriya, S.; Kitahashi, T.; Mahgoub, A.; Mountford, S.J.; Chalmers, D.K.; Soga, T.; Parhar, I.S.; Thompson, P.E. Beta amino acid-modified and fluorescently labelled kisspeptin analogues with potent KISS1R activity. Journal of Peptide Science, 2016, 22(6), 406–414. doi: 10.1002/psc.2883
  77. Geng, L.; Wang, Z.; Jia, X.; Han, Q.; Xiang, Z.; Li, D.; Yang, X.; Zhang, D.; Bu, X.; Wang, W.; Hu, Z.; Fang, Q. HER2 Targeting Peptides Screening and Applications in Tumor Imaging and Drug Delivery. Theranostics, 2016, 6(8), 1261–1273. doi: 10.7150/thno.14302
  78. Richter-Heitmann, T.; Eickhorst, T.; Knauth, S.; Friedrich, M.W.; Schmidt, H. Evaluation of Strategies to Separate Root-Associated Microbial Communities: A Crucial Choice in Rhizobiome Research. Frontiers in Microbiology, 2016, 7, 773. doi: 10.3389/fmicb.2016.00773
  79. Soodgupta, D.; Zhou, H.; Beaino, W.; Lu, L.; Rettig, M.; Snee, M.; Skeath, J.; DiPersio, J.F.; Akers, W.J.; Laforest, R.; Anderson, C.J.; Tomasson, M.H.; Shokeen, M. Ex Vivo and In Vivo Evaluation of Overexpressed VLA-4 in Multiple Myeloma Using LLP2A Imaging Agents. Journal of Nuclear Medicine, 2016, 57(4), 640–645. doi: 10.2967/jnumed.115.164624
  80. Zhong, Q.; Merkel, O.M.; Reineke, J.J.; da Rocha, S.R.P. Effect of the Route of Administration and PEGylation of Poly(amidoamine) Dendrimers on their Systemic and Lung Cellular Biodistribution. Molecular Pharmaceutics, 2016, 13(6), 1866–1878. doi: 10.1021/acs.molpharmaceut.6b00036
  81. Ye, R.; Zhu, C.; Song, Y.; Lu, Q.; Ge, X.; Yang, X.; Zhu, M.-J.; Du, D.; Li, H.; Lin, Y. Bioinspired Synthesis of All-in-One Organic-Inorganic Hybrid Nanoflowers Combined with a Handheld pH Meter for On-Site Detection of Food Pathogen. Small, 2016, 12(23), 3094–3100. doi: 10.1002/smll.201600273
  82. Dou, Y.; Guo, J.; Chen, Y.; Han, S.; Xu, X.; Shi, Q.; Jia, Y.; Liu, Y.; Deng, Y.; Wang, R.; Li, X.; Zhang, J. Sustained delivery by a cyclodextrin material-based nanocarrier potentiates antiatherosclerotic activity of rapamycin via selectively inhibiting mTORC1 in mice. Journal of Controlled Release, 2016, 235, 48–62. doi: 10.1016/j.jconrel.2016.05.049
  83. Yang, Q.; Li, L.; Sun, W.; Zhou, Z.; Huang, Y. Dual Stimuli-Responsive Hybrid Polymeric Nanoparticles Self-Assembled from POSS-Based Star-Like Copolymer-Drug Conjugates for Efficient Intracellular Delivery of Hydrophobic Drugs. ACS Applied Materials & Interfaces, 2016, 8(21), 13251–13261. doi: 10.1021/acsami.6b02403
  84. Brinkman, A.M.; Chen, G.; Wang, Y.; Hedman, C.J.; Sherer, N.M.; Havighurst, T.C.; Gong, S.; Xu, W. Aminoflavone-Loaded EGFR-Targeted Unimolecular Micelle Nanoparticles Exhibit Anti-Cancer Effects in Triple Negative Breast Cancer. Biomaterials, 2016, 101, 20–31. doi: 10.1016/j.biomaterials.2016.05.041
  85. Ray, J.; Shin, I.; Ilgu, M.; Bendickson, L.; Gupta, V.; Kraus, G.A.; Nilsen-Hamilton, M. IMAGEtags: Quantifying mRNA Transcription in Real Time with Multiaptamer Reporters. Methods in Enzymology, 2016, 572, 193–213. doi: 10.1016/bs.mie.2016.02.028
  86. Bygd, H.C.; Bratlie, K.M. The effect of chemically modified alginates on macrophage phenotype and biomolecule transport. Journal of Biomedical Materials Research, 2016, 104(7), 1707–1719. doi: 10.1002/jbm.a.35700
  87. Rana, S.; Blowers, E.C.; Tebbe, C.; Contreras, J.I.; Radhakrishnan, P.; Kizhake, S.; Zhou, T.; Rajule, R.N.; Arnst, J.L.; Munkarah, A.R.; Rattan, R.; Natarajan, A. Isatin Derived Spirocyclic Analogues with α-Methylene-γ-butyrolactone as Anticancer Agents: A Structure-Activity Relationship Study. Journal of Medicinal Chemistry, 2016, 59(10), 5121–5127. doi: 10.1021/acs.jmedchem.6b00400
  88. Chiu, H.-Y.; Deng, W.; Engelke, H.; Helma, J.; Leonhardt, H.; Bein, T. Intracellular chromobody delivery by mesoporous silica nanoparticles for antigen targeting and visualization in real time. Scientific Reports, 2016, 6, 25019. doi: 10.1038/srep25019
  89. Sindhwani, S.; Syed, A.M.; Wilhelm, S.; Glancy, D.R.; Chen, Y.Y.; Dobosz, M.; Chan, W.C.W. Three-Dimensional Optical Mapping of Nanoparticle Distribution in Intact Tissues. ACS Nano, 2016, 10(5), 5468–5478. doi: 10.1021/acsnano.6b01879
  90. Xu, X.; Li, L.; Zhou, Z.; Sun, W.; Huang, Y. Dual-pH responsive micelle platform for co-delivery of axitinib and doxorubicin. International Journal of Pharmaceutics, 2016, 507(1–2), 50–60. doi: 10.1016/j.ijpharm.2016.04.060
  91. Hartley, J.M.; Zhang, R.; Gudheti, M.; Yang, J.; Kopeček, J. Tracking and quantifying polymer therapeutic distribution on a cellular level using 3D dSTORM. Journal of Controlled Release, 2016, 231, 50–59. doi: 10.1016/j.jconrel.2016.02.005
  92. Ngo, J.T.; Adams, S.R.; Deerinck, T.J.; Boassa, D.; Rodriguez-Rivera, F.; Palida, S.F.; Bertozzi, C.R.; Ellisman, M.H.; Tsien, R.Y. Click-EM for imaging metabolically tagged nonprotein biomolecules. Nature Chemical Biology, 2016, 12(6), 459–465. doi: 10.1038/nchembio.2076
  93. Bruckman, M.A.; Czapar, A.E.; VanMeter, A.; Randolph, L.N.; Steinmetz, N.F. Tobacco mosaic virus-based protein nanoparticles and nanorods for chemotherapy delivery targeting breast cancer. Journal of Controlled Release, 2016, 231, 103–113. doi: 10.1016/j.jconrel.2016.02.045
  94. Tran, T.-H.; Krishnan, S.; Amiji, M.M. MicroRNA-223 Induced Repolarization of Peritoneal Macrophages Using CD44 Targeting Hyaluronic Acid Nanoparticles for Anti-Inflammatory Effects. PLoS One, 2016, 11(5), e0152024. doi: 10.1371/journal.pone.0152024
  95. Shen, T.; Guan, S.; Gan, Z.; Zhang, G.; Yu, Q. Polymeric Micelles with Uniform Surface Properties and Tunable Size and Charge: Positive Charges Improve Tumor Accumulation. Biomacromolecules, 2016, 17(5), 1801–1810. doi: 10.1021/acs.biomac.6b00234
  96. Zhao, L.; Yuan, W.; Ang, C.Y.; Qu, Q.; Dai, Y.; Gao, Y.; Luo, Z.; Wang, J.; Chen, H.; Li, M.; Li, F.; Zhao, Y. Silica-Polymer Hybrid with Self-Assembled PEG Corona Excreted Rapidly via a Hepatobiliary Route. Advanced Functional Materials, 2016, 26(18), 3036–3047. doi: 10.1002/adfm.201505155
  97. Liu, C.; Stonestrom, A.J.; Christian, T.; Yong, J.; Takase, R.; Hou, Y.-M.; Yang, X. Molecular Basis and Consequences of the Cytochrome c-tRNA Interaction. Journal of Biological Chemistry, 2016, 291(19), 10426–10436. doi: 10.1074/jbc.M115.697789
  98. Al-Hilal, T.A.; Chung, S.W.; Choi, J.U.; Alam, F.; Park, J.; Kim, S.W.; Kim, S.Y.; Ahsan, F.; Kim, I.-S.; Byun, Y. Targeting prion-like protein doppel selectively suppresses tumor angiogenesis. Journal of Clinical Investigation, 2016, 126(4), 1251–1266. doi: 10.1172/JCI83427
  99. Chen, G.; Jaskula-Sztul, R.; Harrison, A.; Dammalapati, A.; Xu, W.; Cheng, Y.; Chen, H.; Gong, S. KE108-Conjugated Unimolecular Micelles Loaded with a Novel HDAC Inhibitor Thailandepsin-A for Targeted Neuroendocrine Cancer Therapy. Biomaterials, 2016, 97, 22–33. doi: 10.1016/j.biomaterials.2016.04.029
  100. Liu, T.; Yuan, X.; Jia, T.; and Liu, C.; Ni, Z.; Qin, Z.; Yuan, Y. Polymeric Prodrug of Bufalin for Increasing Solubility and Stability: Synthesis and Anticancer Study in Vitro and in Vivo. International Journal of Pharmaceutics, 2016, 506(1–2), 382–393. doi: 10.1016/j.ijpharm.2016.04.041
  101. Jiang, X.; Hu, C.; Arnovitz, S.; Bugno, J.; Yu, M.; Zuo, Z.; Chen, P.; Huang, H.; Ulrich, B.; Gurbuxani, S.; Weng, H.; Strong, J.; Wang, Y.; Li, Y.; Salat, J.; Li, S.; Elkahloun, A.G.; Yang, Y.; Neilly, M.B.; Larson, R.A.; Le Beau, M.M.; Herold, T.; Bohlander, S.K.; Liu, P.P.; Zhang, J.; Li, Z.; He, C.; Jin, J.; Hong, S.; Chen, J.;. miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia. Nature Communications, 2016, 7, 11452. doi: 10.1038/ncomms11452
  102. Pan, G.; Bao, Y.-J.; Xu, J.; Liu, T.; Liu, C.; Qiu, Y.-Y.; Shi, X.-J.; Yu, H.; Jia, T.-T.; Yuan, X.; Yuan, Z.-T.; Yin, P.-H.; Cao, Y.-J. Esterase-responsive polymeric prodrug-based tumor targeting nanoparticles for improved anti-tumor performance against colon cancer. RSC Advances, 2016, 6(48), 42109–42119. doi: 10.1039/c6ra05236c
  103. Kelkar, S.S.; Hill, T.K.; Marini, F.C.; Mohs, A.M. Near infrared fluorescent nanoparticles based on hyaluronic acid: self-assembly, optical properties, and cell interaction. Acta Biomaterialia, 2016, 36, 112–121. doi: 10.1016/j.actbio.2016.03.024
  104. Li, L.; Sun, W.; Zhang, Z.; Huang, Y. Time-staggered delivery of docetaxel and H1S6A,F8A peptide for sequential dual-strike chemotherapy through tumor priming and nuclear targeting. Journal of Controlled Release, 2016, 232, 62–74. doi: 10.1016/j.jconrel.2016.04.021
  105. Zhou, Y.; Li, W.; Xiao, Y. Profiling of Multiple Targets of Artemisinin Activated by Hemin in Cancer Cell Proteome. ACS Chemical Biology, 2016, 11(4), 882–888. doi: 10.1021/acschembio.5b01043
  106. Puthenveetil, S.; Musto, S.; Loganzo, F.; Tumey, L.N.; O'Donnell, C.J.; Graziani, E.I. Development of solid-phase site-specific conjugation and its application towards generation of dual labeled antibody and Fab drug conjugates. Bioconjugate Chemistry, 2016, 27(4), 1030–1039. doi: 10.1021/acs.bioconjchem.6b00054
  107. Zhao, Y.; Fay, F.; Hak, S.; Manuel Perez-Aguilar, J.; Sanchez-Gaytan, B.L.; Goode, B.; Duivenvoorden, R.; de Lange Davies, C.; Bjørkøy, A.; Weinstein, H.; Fayad, Z.A.; Pérez-Medina, C.; Mulder, W.J.M. Augmenting drug-carrier compatibility improves tumour nanotherapy efficacy. Nature Communications, 2016, 7, 11221. doi: 10.1038/ncomms11221
  108. Kwok, S.J.J.; Choi, M.; Bhayana, B.; Zhang, X.; Ran, C.; Yun, S.-H. Two-photon excited photoconversion of cyanine-based dyes. Scientific Reports, 2016, 6, 23866. doi: 10.1038/srep23866
  109. Markovic, S.; Belz, J.; Kumar, R.; Cormack, R.A.; Sridhar, S.; Niedre, M. Near-infrared fluorescence imaging platform for quantifying in vivo nanoparticle diffusion from drug loaded implants. International Journal of Nanomedicine, 2016, 11, 1213–1223. doi: 10.2147/IJN.S93324
  110. Dhande, Y.K.; Wagh, B.S.; Hall, B.C.; Sprouse, D.; Hackett, P.B.; Reineke, T.M. N-Acetylgalactosamine Block-co-Polycations Form Stable Polyplexes with Plasmids and Promote Liver-Targeted Delivery. Biomacromolecules, 2016, 17(3), 830–840. doi: 10.1021/acs.biomac.5b01555
  111. Ravar, F.; Saadat, E.; Gholami, M.; Dehghankelishady, P.; Mahdavi, M.; Azami, S.; Dorkoosh, F.A. Hyaluronic acid-coated liposomes for targeted delivery of paclitaxel, in-vitro characterization and in-vivo evaluation. Journal of Controlled Release, 2016, 229, 10–22. doi: 10.1016/j.jconrel.2016.03.012
  112. Braner, M.; Kollmannsperger, A.; Wieneke, R.; Tampé, R. ’Traceless’ Tracing of Proteins – High-Affinity Trans-Splicing Directed by a Minimal Interaction Pair. Chemical Science, 2016, 7(4), 2646–2652. doi: 10.1039/C5SC02936H
  113. Gupta, A.; Verma, N.C.; Khan, S.; Tiwari, S.; Chaudhary, A.; Nandi, C.K. Paper strip based and live cell ultrasensitive lead sensor using carbon dots synthesized from biological media. Sensors and Actuators B: Chemical, 2016, 232, 107–114. doi: 10.1016/j.snb.2016.03.110
  114. Guldris, N.; Argibay, B.; Kolen'ko, Y.V.; Carbó-Argibay, E.; Sobrino, T.; Campos, F.; Salonen, L.M.; Bañobre-López, M.; Castillo, J.; Rivas, J. Influence of the Separation Procedure on the Properties of Magnetic Nanoparticles: Gaining in vitro Stability and T1‐T2 Magnetic Resonance Imaging Performance. Journal of Colloid and Interface Science, 2016, 472, 229–236. doi: 10.1016/j.jcis.2016.03.040
  115. Li, L.; Grausam, K.B.; Wang, J.; Lun, M.P.; Ohli, J.; Lidov, H.G.W.; Calicchio, M.L.; Zeng, E.; Salisbury, J.L.; Wechsler-Reya, R.J.; Lehtinen, M.K.; Schüller, U.; Zhao, H. Sonic Hedgehog promotes proliferation of Notch-dependent monociliated choroid plexus tumour cells. Nature Cell Biology, 2016, 18(4), 418–430. doi: 10.1038/ncb3327
  116. Ponomarenko, A.I.; Brylev, V.A.; Sapozhnikova, K.A.; Ustinov, A.V.; Prokhorenko, I.A.; Zatsepin, T.S.; Korshun, V.A. Tetrahedral DNA conjugates from pentaerythritol-based polyazides. Tetrahedron, 2016, 72(19), 2386–2391. doi: 10.1016/j.tet.2016.03.051
  117. Seo, K.-H.; Chu, H.-S.; Yoo, T.H.; Lee, S.-G.; Won, J.-I. Separation efficiency of free-solution conjugated electrophoresis with drag-tags incorporating a synthetic amino acid. Electrophoresis, 2016, 37(5–6), 818–825. doi: 10.1002/elps.201500506
  118. Bertrand, A.; Bipfubusa, M.; Castonguay, Y.; Rocher, S.; Szopinska-Morawska, A.; Papadopoulos, Y.; Renaut, J. A proteome analysis of freezing tolerance in red clover (Trifolium pratense L.). BMC Plant Biology, 2016, 16, 65. doi: 10.1186/s12870-016-0751-2
  119. Kim, J.B.; Park, K.; Ryu, Ji.; Lee, J.J.; Lee, M.W.; Cho, H.S.; Nam, H.S.; Park, O.K.; Song, J.W.; Kim, T.S.; Oh, D.J.; Gweon, D.; Oh, W.-Y.; Yoo, H.; Kim, J.W. Intravascular optical imaging of high-risk plaques in vivo by targeting macrophage mannose receptors. Scientific Reports, 2016, 6, 22608. doi: 10.1038/srep22608
  120. Cai, X.; Jin, R.; Wang, J.; Yue, D.; Jiang, Q.; Wu, Y.; Gu, Z. Bioreducible Fluorinated Peptide Dendrimers Capable of Circumventing Various Physiological Barriers for Highly Efficient and Safe Gene Delivery. ACS Applied Materials & Interfaces, 2016, 8(9), 5821–5832. doi: 10.1021/acsami.5b11545
  121. Leenders, J.; Baker, M.B.; Pijpers, I.; Lafleur, R.; Albertazzi, L.; Palmans, A.R.A.; Meijer, E.W. Supramolecular polymerisation in water; elucidating the role of hydrophobic and hydrogen-bond interactions. Soft Matter, 2016, 12, 2887–2893. doi: 10.1039/c5sm02843d
  122. Pitek, A.S.; Jameson, S.A.; Veliz, F.A.; Shukla, S.; Steinmetz, N.F. Serum Albumin "Camouflage" of Plant Virus Based Nanoparticles Prevents Their Antibody Recognition and Enhances Pharmacokinetics. Biomaterials, 2016, 89, 89–97. doi: 10.1016/j.biomaterials.2016.02.032
  123. Ma, G.; Zhao, Z.; Liu, H. Yeast Cells Encapsulating Polymer Nanoparticles as Trojan Particles via in Situ Polymerization inside Cells. Macromolecules, 2016, 49(5), 1545–1551. doi: 10.1021/acs.macromol.6b00016
  124. Iyisan, B.; Kluge, J.; Formanek, P.; Voit, B.; Appelhans, D. Multifunctional and Dual-Responsive Polymersomes as Robust Nanocontainers: Design, Formation by Sequential Post-Conjugations, and pH-Controlled Drug Release. Chemistry of Materials, 2016, 28(5), 1513–1525. doi: 10.1021/acs.chemmater.5b05016
  125. Xue, M.; Wei, W.; Su, Y.; Johnson, D.; Heath, J.R. Supramolecular Probes for Assessing Glutamine Uptake Enable Semi-Quantitative Metabolic Models in Single Cells. Journal of the American Chemical Society, 2016, 138(9), 3085–3093. doi: 10.1021/jacs.5b12187
  126. Rabinsky, E.F.; Joshi, B.P.; Pant, A.; Zhou, J.; Duan, X.; Smith, A.; Kuick, R.; Fan, S.; Nusrat, A.; Owens, S.R.; Appelman, H.D.; Wang, T.D. Overexpressed claudin-1 can be endoscopically visualized in colonic adenomas in vivo. CMGH Cellular and Molecular Gastroenterology and Hepatology, 2016, 2(2), 222–237. doi: 10.1016/j.jcmgh.2015.12.001
  127. Sun, S.; Błażewska, K.M.; Kadina, A.P.; Kashemirov, B.A.; Duan, X.; Triffitt, J.T.; Dunford, J.E.; Russell, R.G.G.; Ebetino, F.H.; Roelofs, A.J.; Coxon, F.P.; Lundy, M.W.; McKenna, C.E. Fluorescent Bisphosphonate and Carboxyphosphonate Probes: A Versatile Imaging Toolkit for Applications in Bone Biology and Biomedicine. Bioconjugate Chemistry, 2016, 27(2), 329–340. doi: 10.1021/acs.bioconjchem.5b00369
  128. Rombouts, K.; Braeckmans, K.; Remaut, K. Fluorescent labeling of plasmid DNA and messenger RNA: gains and losses of current labeling strategies. Bioconjugate Chemistry, 2016, 27(2), 280–297. doi: 10.1021/acs.bioconjchem.5b00579
  129. Liu, X.; Zhang, P.; He, D:; Rödl, W.; Preiß, T.; Rädler, J.O.; Wagner, E.; Lächelt, U. pH-reversible cationic RNase A conjugates for enhanced cellular delivery and tumor cell killing. Biomacromolecules, 2016, 17(1), 173–182. doi: 10.1021/acs.biomac.5b01289
  130. Kijima, S.T.; Hirose, K.; Kong, S.-G.; Wada, M.; Uyeda, T.Q.P. Distinct Biochemical Properties of Arabidopsis thaliana Actin Isoforms. Plant and Cell Physiology, 2016, 57(1), 46–56. doi: 10.1093/pcp/pcv176
  131. Wang, X.; Song, P.; Peng, L.; Tong, A.; Xiang, Y. Aggregation-Induced Emission Luminogen-Embedded Silica Nanoparticles Containing DNA Aptamers for Targeted Cell Imaging. ACS Applied Materials & Interfaces, 2016, 8(1), 609–616. doi: 10.1021/acsami.5b09644
  132. Tolstyka, Z.P.; Phillips, H.; Cortez, M.; Wu, Y.; Ingle, N.; Bell, J.B.; Hackett, P.B.; Reineke, T.M. Trehalose-Based Block Copolycations Promote Polyplex Stabilization for Lyophilization and in Vivo pDNA Delivery. ACS Biomaterials Science & Engineering, 2016, 2(1), 43–55. doi: 10.1021/acsbiomaterials.5b00312
  133. Schelpe, J.; Monté, D.; Dewitte, F.; Sixma, T.K.; Rucktooa, P. Structure of UBE2Z Enzyme Provides Functional Insight into Specificity in the FAT10 Protein Conjugation Machinery. Journal of Biological Chemistry, 2016, 291(2), 630–639. doi: 10.1074/jbc.M115.671545
  134. Yoshimatsu, T.; D'Orazi, F.D.; Gamlin, C.R.; Suzuki, S.C.; Suli, A.; Kimelman, D.; Raible, D.W.; Wong, R.O. Presynaptic partner selection during retinal circuit reassembly varies with timing of neuronal regeneration in vivo. Nature Communications, 2016, 7, 10590. doi: 10.1038/ncomms10590
  135. Li, Z.; Liu, Z.; Chen, Z.; Ju, E.; Li, W.; Ren, J.; Qu, X. Bioorthogonal chemistry for selective recognition, separation and killing bacteria over mammalian cells. Chemical Communications, 2016, 52(17), 3482–3485. doi: 10.1039/c5cc10625g
  136. Panth, K.M.; van den Beucken, T.; Biemans, R.; Lieuwes, N.G.; Weber, M.; Losen, M.; Yaromina, A.; Dubois, L.J.; Lambin, P. In vivo optical imaging of MMP2 immuno protein antibody: tumor uptake is associated with MMP2 activity. Scientific Reports, 2016, 6, 22198. doi: 10.1038/srep22198
  137. Kryvalap, Y.; Lo, C.-W.; Manuylova, E.; Baldzizhar, R.; Jospe, N.; Czyzyk, J. Antibody Response to Serpin B13 Induces Adaptive Changes in Mouse Pancreatic Islets and Slows Down the Decline in the Residual Beta Cell Function in Children with Recent Onset of Type 1 Diabetes Mellitus. Journal of Biological Chemistry, 2016, 291(1), 266–278. doi: 10.1074/jbc.M115.687848
  138. Turcheniuk, K.; Dumych, T.; Bilyy, R.; Turcheniuk, V.; Bouckaert, J.; Vovk, V.; Chopyak, V.; Zaitsev, V.; Mariot, P.; Prevarskaya, N.; Boukherrouba, R.; Szunerits, S. Plasmonic photothermal cancer therapy with gold nanorods/reduced graphene oxide core/shell nanocomposites. RSC Advances, 2016, 6(2), 1600–1610. doi: 10.1039/c5ra24662h
  139. Wang, X.; Wang, C.; Zhang, Q.; Cheng, Y. Near Infrared Light-responsive and Injectable Supramolecular Hydrogels for On-demand Drug Delivery. Chemical Communications, 2016, 52, 978–981. doi: 10.1039/c5cc08391e
  140. He, H.; Altomare, D.; Ozer, U.; Xu, H.; Creek, K.; Chen, H.; Xu, P. Cancer cell-selective killing polymer/copper combination. Biomaterials Science, 2016, 4(1), 115–120. doi: 10.1039/c5bm00325c
  141. Poongavanam, M.-V.; Kisley, L.; Kourentzi, K.; Landes, C.F.; Willson, C. Ensemble and Single-Molecule Biophysical Characterization of D17.4 DNA Aptamer-IgE Interactions. Biochimica et Biophysica Acta, 2016, 1864(1), 154–164. doi: 10.1016/j.bbapap.2015.08.008
  142. Saita, M.; Kaneko, J.; Sato, T.; Takahashi, S.; Takahashi, S.W.; Kawamata, R.; Sakurai, T.; Lee, M.-C.; Hamada, N.; Kimoto, K.; Nagasaki, Y. Novel antioxidative nanotherapeutics in a rat periodontitis model: Reactive oxygen species scavenging by redox injectable gel suppresses alveolar bone resorption. Biomaterials, 2016, 76, 292–301. doi: 10.1016/j.biomaterials.2015.10.077
  143. Nusshold, C.; Üllen, A.; Kogelnik, N.; Bernhart, E.; Reicher, H.; Plastira, I.; Glasnov, T.; Zangger, K.; Rechberger, G.; Kollroser, M.; Fauler, G.; Wolinski, H.; Weksler, B.B.; Romero, I.A.; Kohlwein, S.D.; Couraud, P.-O.; Malle, E.; Sattler, W. Assessment of electrophile damage in a human brain endothelial cell line utilizing a clickable alkyne analogue of 2-chlorohexadecanal. Free Radical Biology and Medicine, 2016, 90, 59–74. doi: 10.1016/j.freeradbiomed.2015.11.010
  144. van der Velde, J.H.M.; Oelerich, J.; Huang, J.; Smit, J.H.; Aminian Jazi, A.; Galiani, S.; Kolmakov, K.; Guoridis, G.; Eggeling, C.; Herrmann, A.; Roelfes, G.; Cordes, T. A simple and versatile design concept for fluorophore derivatives with intramolecular photostabilization. Nature Communications, 2016, 7, 10144. doi: 10.1038/ncomms10144
  145. Zhang, L.; Thurber, G.M. Quantitative Impact of Plasma Clearance and Down-regulation on GLP-1 Receptor Molecular Imaging. Molecular Imaging and Biology, 2016, 18(1), 79–89. doi: 10.1007/s11307-015-0880-2
  146. Poolman, J.; Maity, C.; Boekhoven, J.; van der Mee, L.; le Sage, V.; Groenewold, M.; van Kasteren, S.; Versluis, F.; van Esch, J.; Eelkema, R. A toolbox for controlling the properties and functionalisation of hydrazone-based supramolecular hydrogels. Journal of Materials Chemistry B, 2016, 4, 852–858. doi: 10.1039/C5TB01870F
  147. Aparin, I.O.; Farzan, V.M.; Veselova, O.A.; Chistov, A.A.; Podkolzin, A.T.; Ustinov, A.V.; Shipulin, G.A.; Formanovsky, A.A.; Korshun, V.A.; Zatsepin, T.S. 1-Phenylethynylpyrene (PEPy) as a novel blue-emitting dye for qPCR assay. Analyst, 2016, 141, 1331–1338. doi: 10.1039/c5an01767j
  148. Joshi, B.P.; Zhou, J.; Pant, A.; Duan, X.; Zhou, Q.; Kuick, R.; Owens, S.R.; Appelman, H.; Wang, T.D. Design and Synthesis of Near-Infrared Peptide for in Vivo Molecular Imaging of HER2. Bioconjugate Chemistry, 2016, 27(2), 481–494. doi: 10.1021/acs.bioconjchem.5b00565
  149. Stephen, Z.; Dayringer, C.; Lim, J.; Revia, R.; Halbert, M.; Jeon, M.; Bakthavatsalam, A.; Ellenbogen, R.G.; Zhang, M. An Approach to Rapid Synthesis and Functionalization of Iron Oxide Nanoparticles for High Gene Transfection. ACS Applied Materials & Interfaces, 2016, 8(10), 6320–6328. doi: 10.1021/acsami.5b10883
  150. Park, H.; Koo, J.Y.; Srikanth, Y.V.V.; Oh, S.; Lee, J.; Park, J.; Park, S.B. Nonspecific protein labeling of photoaffinity linkers correlates with their molecular shapes in living cells. Chemical Communications, 2016, 52(34), 5828–5831. doi: 10.1039/c6cc01426g
  151. Gaitzsch, J.; Delahaye, M.; Poma, A.; Du Prez, F.; Battaglia, G. Comparison of metal free polymer-dye conjugation strategies in protic solvents. Polymer Chemistry, 2016, 7(17), 3046–3055;. doi: 10.1039/c6py00518g
  152. Subedi, M.; Minn, I.; Chen, J.; Kim, Y.; Ok, K.; Jung, Y.W.; Pomper, M.G.; Byun, Y. Design, synthesis and biological evaluation of PSMA/hepsin-targeted heterobivalent ligands. European Journal of Medicinal Chemistry, 2016, 118, 208–218. doi: 10.1016/j.ejmech.2016.04.033
  153. Shebl, B., Menke, D.E.; Pennella, M.; Poudyal, R.R.; Burke, D.H.; Cornish, P.V. Preparation of ribosomes for smFRET studies: A simplified approach. Archives of Biochemistry and Biophysics, 2016, 603, 118–130. doi: 10.1016/j.abb.2016.05.010
  154. Yoshimura, T.; Harashima, M.; Kurogi, K.; Suiko, M.; Liu, M.-C.; Sakakibara, Y. A novel procedure for the assessment of the antioxidant capacity of food components. Analytical Biochemistry, 2016, 507, 7–12. doi: 10.1016/j.ab.2016.05.002
  155. Bipfubusa, M.; Rocher, S.; Bertrand, A.; Castonguay, Y.; Renaut, J. Dataset of protein changes induced by cold acclimation in red clover (Trifolium pratense L.) populations recurrently selected for improved freezing tolerance. Data in Brief, 2016, 8, 570–574. doi: 10.1016/j.dib.2016.06.003
  156. Zhang, Z.; Cai, H.; Liu, Z.; Yao, P. Effective Enhancement of Hypoglycemic Effect of Insulin by Liver-targeted Nanoparticles Containing Cholic Acid-modified Chitosan Derivative. Molecular Pharmaceutics, 2016, 13(7), 2433–2442. doi: 10.1021/acs.molpharmaceut.6b00188
  157. Khaliq, N.U.; Park, D.Y.; Lee, J.Y.; Joo, Y.; Oh, K.S.; Kim, J.S.; Kim, J.-S.; Kim, I.-S.; Kwon, I.C.; Yuk, S.H. The multilayer nanoparticles for deep penetration of docetaxel into tumor parenchyma to overcome tumor microenvironment. Colloids and Surfaces B: Biointerfaces, 2016, 146, 833–840. doi: 10.1016/j.colsurfb.2016.07.034
  158. Gao, P.; Hunter, A.J.; Summe, M.J.; Phillip, W.A. A Method for the Efficient Fabrication of Multifunctional Mosaic Membranes by Inkjet Printing. ACS Applied Materials & Interfaces, 2016, 8(30), 19772–19779. doi: 10.1021/acsami.6b06048
  159. Horning, D.P.; Joyce, G.F. Amplification of RNA by an RNA polymerase ribozyme. Proceedings of the National Academy of Sciences of the United States of America, 2016, 113(35), 9786–9791. doi: 10.1073/pnas.1610103113
  160. Chadda, R.; Krishnamani, V.; Mersch, K.; Wong, J.; Brimberry, M.; Chadda, A.; Kolmakova-Partensky, L.; Friedman, L.J.; Gelles, J.; Robertson, J.L. The dimerization equilibrium of a ClC Cl−/H+ antiporter in lipid bilayers. eLIFE, 2016, 5, e17438. doi: 10.7554/eLife.17438
  161. Du, N.; Guo, W.; Yu, Q.; Guan, S.; Guo, L.; Shen, T.; Tang, H.; Gan, Z. Poly(D,L-lactic acid)-block-poly(N-(2-hydroxypropyl)methacrylamide) nanoparticles for overcoming accelerated blood clearance and achieving efficient anti-tumor therapy. Polymer Chemistry, 2016, 7(36), 5719–5729. doi: 10.1039/c6py01113f
  162. Shao, J.; Xie, H.; Huang, H.; Li, Z.; Sun, Z.; Xu, Y.; Xiao, Q.; Yu, X.-F.; Zhao, Y.; Zhang, H.; Wang, H.; Chu, P.K. Biodegradable black phosphorus-based nanospheres for in vivo photothermal cancer therapy. Nature communications, 2016, 7, 12967. doi: 10.1038/ncomms12967
  163. Hu, H.; Li, Y.; Zhou, Q.; Ao, Y.; Yu, C.; Wan, Y.; Xu, H.-B.; Li, Z.; Yang, X. Redox-sensitive hydroxyethyl starch-doxorubicin conjugate for tumor targeted drug delivery. ACS Applied Materials & Interfaces, 2016, 8(45), 30833–30844. doi: 10.1021/acsami.6b11932
  164. Chen, Y.; Luan, J.; Shen, W.; Lei, K.; Yu, L.; Ding, J. Injectable and thermosensitive hydrogel containing liraglutide as a long-acting anti-diabetic system. ACS Applied Materials & Interfaces, 2016, 8(45), 30703–30713. doi: 10.1021/acsami.6b09415
  165. Zhao, Y.; Wei, Z.; Zhao, H.; Jia, J.; Chen, Z.; Zhang, S.; Ouyang, Z.; Ma, X.; Zhang, X. In situ Ion-Transmission Mass Spectrometry for Paper-Based Analytical Devices. Analytical Chemistry, 2016, 88(22), 10805–10810. doi: 10.1021/acs.analchem.6b03272
  166. Matsuo, Y.; Maurer, S.P.; Yukawa, M.; Zakian, S.; Singleton, M.R.; Surrey, T.; Toda, T. An unconventional interaction between Dis1/TOG and Mal3/EB1 promotes the fidelity of chromosome segregation. Journal of Cell Science, 2016, 129(24), 4592–4606. doi: 10.1242/jcs.197533
  167. Li, W.; Zhou, Y.; Tang, G.; Xiao, Y. Characterization of the Artemisinin Binding Site for Translationally Controlled Tumor Protein (TCTP) by Bioorthogonal Click Chemistry. Bioconjugate Chemistry, 2016, 27(12), 2828–2833. doi: 10.1021/acs.bioconjchem.6b00556
  168. Song, X.; Hong, S.-H.; Kwon, W.T.; Bailey, L.M.; Basse, P.; Bartlett, D.L.; Kwon, Y.T.; Lee, Y.J. Secretory TRAIL-armed Natural Killer Cell-based Therapy: In Vitro and In Vivo Colorectal Peritoneal Carcinomatosis Xenograft. Molecular Cancer Therapeutics, 2016, 15(7), 1591-1601. doi: 10.1158/1535-7163.MCT-15-0937

2015

  1. Alam, F.; Chung, S.W.; Hwang, S.R.; Kim, J.-y.; Park, J.; Moon, H.T.; Byun, Y. Preliminary safety evaluation of a taurocholate-conjugated low-molecular-weight heparin derivative (LHT7): a potent angiogenesis inhibitor. Journal of Applied Toxicology, 2015, 35(1), 104–115. doi: 10.1002/jat.2995
  2. Gremse, F.; Doleschel, D.; Zafarnia, S.; Babler, A.; Jahnen-Dechent, W.; Lammers, T.; Lederle, W.; Kiessling, F. Hybrid µCT-FMT imaging and image analysis. Journal of Visualized Experiments, 2015, e52770. doi: 10.3791/52770
  3. Wang, H.; Li, D.; Liu, S.; Liu, R.; Yuan, H.; Krasnoperov, V.; Shan, H.; Conti, P.S.; Gill, P.S.; Li, Z. Small-Animal PET Imaging of Pancreatic Cancer Xenografts Using a 64Cu-Labeled Monoclonal Antibody, MAb159. Journal of Nuclear Medicine, 2015, 56(6), 908–913. doi: 10.2967/jnumed.115.155812
  4. Mahmoodi, M.M.; Rashidian, M.; Zhang, Y.; Distefano, M.D. Application of meta- and para- Phenylenediamine as Enhanced Oxime Ligation Catalysts for Protein Labeling, PEGylation, Immobilization, and Release. Current Protocols in Protein Science, 2015, 79, 15.4.1–15.4.28. doi: 10.1002/0471140864.ps1504s79
  5. Zhang, Rui and Yang, Jiyuan and Chu, Te-Wei and Hartley, Jonathan M. and Kopeček, Jindřich. Multimodality Imaging of Coiled-Coil Mediated Self-Assembly in a "Drug-Free" Therapeutic System. Advanced Healthcare Materials, 2015, 4(7), 1054–1065. doi: 10.1002/adhm.201400679
  6. Shrivastava, R.; Köster, D.; Kalme, S.; Mayor, S.; Neerathilingam, M. Tailor-made ezrin actin binding domain to probe its interaction with actin in-vitro. PLoS One, 2015, 10(4), e0123428. doi: 10.1371/journal.pone.0123428
  7. Evans, L.E.; Cheeseman, M.D.; Yahya, N.; Jones, K. Investigating Apoptozole as a Chemical Probe for HSP70 Inhibition. PLoS One, 2015, 10(10), e0140006. doi: 10.1371/journal.pone.0140006
  8. Schembri, L.S.; Stoddart, L.A.; Briddon, S.J.; Kellam, B.; Canals, M.; Graham, B.; Scammells, P.J. Synthesis, Biological Evaluation, and Utility of Fluorescent Ligands Targeting the μ-Opioid Receptor. Journal of Medicinal Chemistry, 2015, 58(24), 9764–9767. doi: 10.1021/acs.jmedchem.5b01664
  9. Chu, D.; Gao, J.; Wang, Z. Neutrophil-Mediated Delivery of Therapeutic Nanoparticles across Blood Vessel Barrier for Treatment of Inflammation and Infection. ACS Nano, 2015, 9(12), 11800–11811. doi: 10.1021/acsnano.5b05583
  10. Bu, J.; Pilo, A.L.; McLuckey, S.A. Gas Phase Click Chemistry via Ion/Ion Reactions. International Journal of Mass Spectrometry, 2015, 390, 118–123. doi: 10.1016/j.ijms.2015.05.010
  11. Rudnick-Glick, S.; Corem-Salkmon, E.; Grinberg, I.; Yehuda, R.; Margel, S. Near IR fluorescent conjugated poly(ethylene glycol)bisphosphonate nanoparticles for in vivo bone targeting in a young mouse model. Journal of Nanobiotechnology, 2015, 13(1), 80. doi: 10.1186/s12951-015-0126-0
  12. Koo, H.; Choi, M.; Kim, E.; Hahn, S.K.; Weissleder, R.; Yun, S.H. Bioorthogonal Click Chemistry-Based Synthetic Cell Glue. Small, 2015, 11(48), 6458–6466. doi: 10.1002/smll.201502972
  13. Lehtivuori, H.; Bhattacharya, S.;Angenent-Mari, N.M.; Satyshur, K.A.; Forest, K.T. Removal of Chromophore-Proximal Polar Atoms Decreases Water Content and Increases Fluorescence in a Near Infrared Phytofluor. Frontiers in Molecular Biosciences, 2015, 2, 65. doi: 10.3389/fmolb.2015.00065
  14. Wang, Z.; Zourelias, L.; Wu, C.; Edwards, P.C.; Trombetta, M.; Passineau, M.J. Ultrasound-assisted nonviral gene transfer of AQP1 to the irradiated minipig parotid gland restores fluid secretion. Gene Therapy, 2015, 22, 739–749. doi: 10.1038/gt.2015.36
  15. Sun, L.; Gai, Y.; Anderson, C.J.; Zeng, D. Highly-efficient and versatile fluorous-tagged Cu(I)-catalyzed azide–alkyne cycloaddition ligand for preparing bioconjugates. Chemical Communications, 2015, 51, 17072–17075. doi: 10.1039/C5CC06858D
  16. Cilliers, C.; Liao, J.; Atangcho, L.; Thurber, G.M. Residualization Rates of Near-Infrared Dyes for the Rational Design of Molecular Imaging Agents. Molecular Imaging and Biology, 2015, 17(6), 757–762. doi: 10.1007/s11307-015-0851-7
  17. Calver, C.F.; Liu, H.-W.; Cosa, G. Exploiting Conjugated Polyelectrolyte Photophysics towards Monitoring Real-Time Lipid Membrane-Surface Interaction Dynamics at the Single Particle Level. Langmuir, 2015, 31(43), 11842–11850. doi: 10.1021/acs.langmuir.5b00979
  18. Alexander, S.C.; Busby, K.N.; Cole, C.M.; Zhou, C.Y.; Devaraj, N.K. Site-Specific Covalent Labeling of RNA by Enzymatic Transglycosylation. Journal of the American Chemical Society, 2015, 137(40), 12756–12759. doi: 10.1021/jacs.5b07286
  19. Barlow, N.; Nasser, Y.; Zhao, P.; Sharma, N.; Guerrero-Alba, R.; Edgington-Mitchell, L.E.; Lieu, T.; Veldhuis, N.A.; Poole, D.P.; Conner, J.W.; Lindström, E.; Craig, A.W.; Graham, B.; Vanner, S.J.; Bunnett, N.W. Demonstration of elevated levels of active cathepsin S in dextran sulfate sodium colitis using a new activatable probe. Neurogastroenterology and Motility, 2015, 27(11), 1675–1680. doi: 10.1111/nmo.12656
  20. Gao, D.; Zhang, P.; Liu, C.; Chen, C.; Gao, G.; Wu, Y.; Sheng, Z.; Song, L.; Cai, L. Compact chelator-free Ni-integrated CuS nanoparticles with tunable near-infrared absorption and enhanced relaxivity for in vivo dual-modal photoacoustic/MR imaging. Nanoscale, 2015, 7, 17631–17636. doi: 10.1039/C5NR05237H
  21. Albertazzi, L.; van der Veeken, N.; Baker, M.B.; Palmans, A.R.A.; Meijer, E.W. Supramolecular copolymers with stimuli-responsive sequence control. Chemical Communications, 2015, 51(90), 16166–16168. doi: 10.1039/c5cc06951c
  22. Demillo, V.G.; Zhu, X. Zwitterionic amphiphile coated magnetofluorescent nanoparticles – synthesis, characterization and tumor cell targeting. Journal of Materials Chemistry B, 2015, 3, 8328–8336. doi: 10.1039/C5TB01116G
  23. Wang, C.; Wang, Y.; Li, Y.; Bodemann, B.; Zhao, T.; Ma, X.; Huang, G.; Hu, Z.; DeBerardinis, R.J.; White, M.A.; Gao, J. A nanobuffer reporter library for fine-scale imaging and perturbation of endocytic organelles. Nature Communications, 2015, 6, 8524. doi: 10.1038/ncomms9524
  24. Zhou, B.; Wang, H.; Liu, R.; Wang, M.; Deng, H.; Giglio, B.; Gill, P.S.; Shan, H.; Li, Z. PET Imaging of Dll4 Expression in Glioblastoma and Colorectal Cancer Xenografts Using 64Cu-Labeled Monoclonal Antibody 61B. Molecular Pharmaceutics, 2015, 12(10), 3527–3534. doi: 10.1021/acs.molpharmaceut.5b00105
  25. Yang, J.; Zhang, R.; Radford, D.C.; Kopeček, J. FRET-trackable biodegradable HPMA copolymer-epirubicin conjugates for ovarian carcinoma therapy. Journal of Controlled Release, 2015, 218, 36–44. doi: 10.1016/j.jconrel.2015.09.045
  26. Fuchs, A.V.; Tse, B.W.C.; Pearce, A.K.; Yeh, M.-C.; Fletcher, N.L.; Huang, S.S.; Heston, W.D.; Whittaker, A.K.; Russell, P.J.; Thurecht, K.J. Evaluation of Polymeric Nanomedicines Targeted to PSMA: Effect of Ligand on Targeting Efficiency. Biomacromolecules, 2015, 16(10), 3235–3247. doi: 10.1021/acs.biomac.5b00913
  27. Abolmaali, S.; Tamaddon, A.; Kamali-Sarvestani, E.; Ashraf, M.; Dinarvand, R. Stealth Nanogels of Histinylated Poly Ethyleneimine for Sustained Delivery of Methotrexate in Collagen-Induced Arthritis Model. Pharmaceutical Research, 2015, 32(10), 3309–3323. doi: 10.1007/s11095-015-1708-0
  28. Yu, Q.; Wei, Z.; Shi, J.; Guan, S.; Du, N.; Shen, T.; Tang, H.; Jia, B.; Wang, F.; Gan, Z. Polymer-Doxorubicin Conjugate Micelles Based on Poly(ethylene glycol) and Poly(N-(2-hydroxypropyl) methacrylamide): Effect of Negative Charge and Molecular Weight on Biodistribution and Blood Clearance. Biomacromolecules, 2015, 16(9), 2645–2655. doi: 10.1021/acs.biomac.5b00460
  29. Schwarz, B.; Madden, P.; Avera, J.; Gordon, B.; Larson, K.; Miettinen, H.; Uchida, M.; LaFrance, B.; Basu, G.; Rynda-Apple, A.; Douglas, T. Symmetry Controlled, Genetic Presentation of Bio-Active Proteins on the P22 Virus-Like Particle Using an External Decoration Protein. ACS Nano, 2015, 9(9), 9134–9147. doi: 10.1021/acsnano.5b03360
  30. Bruckman, M.; Randolph, L.; Gulati, N.; Stewart, P.; Steinmetz, N.F. Silica mineralization of Gd(DOTA)-loaded viral nanoparticles enhances MRI relaxivity and avoids immune recognition. Journal of Materials Chemistry B, 2015, 3(38), 7503–7510. doi: 10.1039/c5tb01014d
  31. Terekhov, S., Smirnov, I.; Bobik, T.; Shamborant, O.; Zenkova, M.; Chernolovskaya, E.; Gladkikh, D.; Murashev, A.; Dyachenko, I.; Palikov, V.; Palikova, Y.; Knorre, V.; Belogurov Jr, A.; Ponomarenko, N.; Blackburn, G.M.; Masson, P.; Gabibov, A. A novel expression cassette delivers efficient production of exclusively tetrameric human butyrylcholinesterase with improved pharmacokinetics for protection against organophosphate poisoning. Biochimie, 2015, 118, 51–59. doi: 10.1016/j.biochi.2015.07.028
  32. Vanparijs, N.; De Coen, R.; Laplace, D.R.; Louage, B.; Maji, S.; Lybaert, L.; Hoogenboom, R.; De Geest, B. Transiently responsive protein-polymer conjugates via a grafting-from RAFT approach: for intracellular co-delivery of proteins and immune-modulators. Chemical Communications, 2015, 51, 13972–13975. doi: 10.1039/c5cc04809e
  33. Chen, L.; An, H.; Doyle, P.S. Synthesis of non-spherical microcapsules through controlled polyelectrolyte coating of hydrogel templates. Langmuir, 2015, 31(33), 9228–9235. doi: 10.1021/acs.langmuir.5b02200
  34. Li, H.; Yang, Z.-Y.; Liu, C.; Zeng, Y.-P.; Hao, Y.-H. Gu, Y.; Wang, W.-D.; Li, R. PEGylated ceria nanoparticles used for radioprotection on Human liver cells under γ-ray irradiation. Free Radical Biology and Medicine, 2015, 87, 26–35. doi: 10.1016/j.freeradbiomed.2015.06.010
  35. Geng, L.; Wang, Z.; Yang, X.; Li, D.; Lian, W.; Xiang, Z.; Wang, W.; Bu, X.; Lai, W.; Hu, Z.; Fang, Q. Structure-based Design of Peptides with High Affinity and Specificity to HER2 Positive Tumors. Theranostics, 2015, 5(10), 1154–1165. doi: 10.7150/thno.12398
  36. Schmidt, W.M.; Lehman, W.; Moore, J.R. Direct observation of tropomyosin binding to actin filaments. Cytoskeleton, 2015, 72(6), 292–303. doi: 10.1002/cm.21225
  37. Stone, R.C.; Fellows, B.D.; Qi, B.; Trebatowski, D.; Jenkins, B.; Raval, Y.; Tzeng, T.R.; Bruce, T.F.; Mcnealy, T.; Austin, M.J.; Monson, T.C.; Huber, D.L.; Mefford, O.T. Highly Stable Multi-Anchored Magnetic Nanoparticles for Optical Imaging within Biofilms. Journal of Colloid and Interface Science, 2015, 459, 175–182. doi: 10.1016/j.jcis.2015.08.012
  38. Chung, S.W.; Lee, B.S. Choi, J.U.; Kim, S.W.; Kim, I.-S.; Kim, S.Y.; Byun, Y. Optimization of a stable linker involved DEVD peptide-doxorubicin conjugate that is activated upon radiation-induced caspase-3-mediated apoptosis. Journal of Medicinal Chemistry, 2015, 58(16), 6435–6447. doi: 10.1021/acs.jmedchem.5b00420
  39. Li, X.-P.; Jing, W.; Sun, J.-J.; Liu, Z.-Y.; Zhang, J.-T.; Sun, W.; Zhu, W.; Fan, Y.-Z. A potential small-molecule synthetic antilymphangiogenic agent norcantharidin inhibits tumor growth and lymphangiogenesis of human colonic adenocarcinomas through blocking VEGF-A,-C,-D/VEGFR-2,-3 "multi-points priming" mechanisms in vitro and ... BMC Cancer, 2015, 15, 527. doi: 10.1186/s12885-015-1521-5
  40. Ilnitskaya, E.V.; Kononevich, Y.N.; Muzafarov, A.M.; Rzhevskiy, S.A.; Shadrin, I.A.; Babaev, E.V.; Martynov, V.I.; Pakhomov, A.A. Preparation and application of a BODIPY-labeled probe for a real-time polymerase chain reaction. Russian Journal of Bioorganic Chemistry, 2015, 41(4), 451–453. doi: 10.1134/S1068162015040068
  41. Park, H.-K.; Lee, S.J.; Oh, J.-S.; Lee, S.-G.; Jeong, Y.-I.; Lee, H.C. Smart Nanoparticles Based on Hyaluronic Acid for Redox-Responsive and CD44 Receptor-Mediated Targeting of Tumor. Nanoscale Research Letters, 2015, 10(1), 981. doi: 10.1186/s11671-015-0981-5
  42. Guo, Y.; Wang, D.; Song, Q.; Wu, T.; Zhuang, X.; Bao, Y.; Kong, M.; Qi, Y.; Tan, S.; Zhang, Z. Erythrocyte Membrane-Enveloped Polymeric Nanoparticles as Nanovaccine for Induction of Antitumor Immunity against Melanoma. ACS Nano, 2015, 9(7), 6918–6933. doi: 10.1021/acsnano.5b01042
  43. Shi, Q.; Zhang, L.; Liu, M.; Zhang, X.; Zhang, X.; Xu, X.; Chen, S.; Li, X.; Zhang, J. Reversion of multidrug resistance by a pH-responsive cyclodextrin-derived nanomedicine in drug resistant cancer cells. Biomaterials, 2015, 67, 169–182. doi: 10.1016/j.biomaterials.2015.07.023
  44. Søndergaard, S.; Aznauryan, M.; Haustrup, E.K.; Schiøtt, B.; Birkedal, V.; Corry, B. Dynamics of Fluorescent Dyes Attached to G-Quadruplex DNA and their Effect on FRET Experiments. ChemPhysChem, 2015, 16(12), 2562–2570. doi: 10.1002/cphc.201500271
  45. Lu, J.; Zhou, Z.; Zheng, J.; Zhang, Z.; Lu, R.; Liu, H.; Shi, H.; Tu, Z. 2D-DIGE and MALDI TOF/TOF MS analysis reveal that small GTPase signaling pathways may play an important role in cadmium-induced colon cell malignant transformation. Toxicology and Applied Pharmacology, 2015, 288(1), 106–113. doi: 10.1016/j.taap.2015.07.020
  46. Fu, B.; Flynn, J.D.; Isaacoff, B.P.; Rowland, D.J.; Biteen, J.S. Super-Resolving the Distance-Dependent Plasmon-Enhanced Fluorescence of Single Dye and Fluorescent Protein Molecules. The Journal of Physical Chemistry C, 2015, 119(33), 19350–19358. doi: 10.1021/acs.jpcc.5b05154
  47. Klykov, O.; Weller, M.G. Quantification of N-hydroxysuccinimide and N-hydroxysulfosuccinimide by hydrophilic interaction chromatography (HILIC). Analytical Methods, 2015, 7, 6443–6448. doi: 10.1039/c5ay00042d
  48. Li, L.; Sun, W.; Zhong, J.; Yang, Qi.; Zhu, X.; Zhou, Z.; Zhang Z.; Huang, Y. Multistage Nanovehicle Delivery System Based on Stepwise Size Reduction and Charge Reversal for Programmed Nuclear Targeting of Systemically Administered Anticancer Drugs. Advanced Functional Materials, 2015, 25(26), 4101–4113. doi: 10.1002/adfm.201501248
  49. Zhong, J.; Li, L.; Zhu, X.; Guan, S.; Yang, Q.; Zhou, Z.; Zhang, Z.; Huang, Y. A smart polymeric platform for multistage nucleus-targeted anticancer drug delivery. Biomaterials, 2015, 65, 43–55. doi: 10.1016/j.biomaterials.2015.06.042
  50. Zhou, J.; Joshi, B.P.; Duan, X.; Pant, A.; Qiu, Z.; Kuick, R.; Owens, S.R.; Wang, T.D. EGFR Overexpressed in Colonic Neoplasia Can be Detected on Wide-Field Endoscopic Imaging. Clinical and Translational Gastroenterology, 2015, 6, e101. doi: 10.1038/ctg.2015.28
  51. Ma, Y.; Fuchs, A.; Boase, N.R.B.; Rolfe, B.E.; Coombes, A.G.A.; Thurecht, K.J. The in vivo fate of nanoparticles and nanoparticle-loaded microcapsules after oral administration in mice: evaluation of their potential for colon-specific delivery. European Journal of Pharmaceutics and Biopharmaceutics, 2015, 94, 393–403. doi: 10.1016/j.ejpb.2015.06.014
  52. Vega, B.; Wondraczek, H.; Bretschneider, L.; Näreoja, T.; Fardim, P.; Heinze, T. Preparation of reactive fibre interfaces using multifunctional cellulose derivatives. Carbohydrate Polymers, 2015, 132, 261–273. doi: 10.1016/j.carbpol.2015.05.048
  53. Chuang, E.-Y.; Lin, K.-J.; Lin, P.-Y. Chen, H.-L. Wey, S.-P. Mi, F.-L. Hsiao, H.-C. Chen, C.-T.; Sung, H.-W. Self-Assembling Bubble Carriers for Oral Protein Delivery. Biomaterials, 2015, 64, 115–124. doi: 10.1016/j.biomaterials.2015.06.035
  54. Huang, X.; He, J.; Hao, Y.; Ye, M.; Zhang, Q.; Ni, P.; Liu, J. Synthesis of PEGylated brush-type copolymers for a plurality of plug-and-play functions. RSC Advances, 2015, 5(62), 50019–50023. doi: 10.1039/c5ra06484h
  55. Mohan, K.; Penner, R.M.; Weiss, G.A. Biosensing with Virus Electrode Hybrids. Current Protocols in Chemical Biology, 2015, 7, 53–73. doi: 10.1002/9780470559277.ch140213
  56. Wilks, M.Q.; Normandin, M.D.; Yuan, H.; Cho, H.; Guo, Y.; Herisson, F.; Ayata, C.; Wooten, D.W.; El Fakhri, G.; Josephson, L. Imaging PEG-Like Nanoprobes in Tumor, Transient Ischemia, and Inflammatory Disease Models. Bioconjugate Chemistry, 2015, 26(6), 1061–1069. doi: 10.1021/acs.bioconjchem.5b00213
  57. Wanat, P.; Walczak, S.; Wojtczak, B.A.; Nowakowska, M.; Jemielity, J.; Kowalska, J. Ethynyl, 2-Propynyl, and 3-Butynyl C-Phosphonate Analogues of Nucleoside Di- and Triphosphates: Synthesis and Reactivity in CuAAC. Organic Letters, 2015, 17(12), 3062–3065. doi: 10.1021/acs.orglett.5b01346
  58. Han, F.Y.; Thurecht, K.J.; Lam, A.-L.; Whittaker, A.K.; Smith, M.T. Novel Polymeric Bioerodable Microparticles for Prolonged-Release Intrathecal Delivery of Analgesic Agents for Relief of Intractable Cancer-Related Pain. Journal of Pharmaceutical Sciences, 2015, 104(7), 2334–2344. doi: 10.1002/jps.24497
  59. Noriega, R.; Finley, D.T.; Haberstroh, J.; Geissler, P.L.; Francis, M.B.; Ginsberg, N.S. Manipulating Excited-State Dynamics of Individual Light-Harvesting Chromophores through Restricted Motions in a Hydrated Nanoscale Protein Cavity. The Journal of Physical Chemistry B, 2015, 119(23), 6963–6973. doi: 10.1021/acs.jpcb.5b03784
  60. Maity, A.; Macaubas, C.; Mellins, E.; Astakhova, K. Synthesis of Phospholipid-Protein Conjugates as New Antigens for Autoimmune Antibodies. Molecules, 2015, 20(6), 10253–10263. doi: 10.3390/molecules200610253
  61. Singh, S.; Pal, K.; Yadav, J.; Tang, H.; Partyka, K.; Kletter, D.; Hsueh, P.; Ensink, E.; KC, B.; Hostetter, G.; Xu, H.E.; Bern, M.; Smith, D.F.; Mehta, A.S.; Brand, R.; Melcher, K.; Haab, B.B. Upregulation of Glycans Containing 3' Fucose in a Subset of Pancreatic Cancers Uncovered Using Fusion-Tagged Lectins. Journal of Proteome Research, 2015, 14(6), 2594–2605. doi: 10.1021/acs.jproteome.5b00142
  62. Printz, B.; Guerriero, G.; Sergeant, K.; Renaut, J.; Lutts, S.; Hausman, J.-F. Ups and downs in alfalfa: Proteomic and metabolic changes occurring in the growing stem. Plant Science, 2015, 238, 13–25. doi: 10.1016/j.plantsci.2015.05.014
  63. Unciti-Broceta, J.D.; Cano-Cortés, V.; Altea-Manzano, P.; Pernagallo, S.; Díaz-Mochón, J.J.; Sánchez-Martín, R.M. Number of Nanoparticles per Cell through a Spectrophotometric Method – A key parameter to Assess Nanoparticle-based Cellular Assays. Scientific Reports, 2015, 5, 10091. doi: 10.1038/srep10091
  64. Han, Z.; Zhou, Z.; Shi, X.; Wang, J.; Wu, X.; Sun, D.; Chen, Y.; Zhu, H.; Magi-Galluzzi, C.; Lu, Z.-R. EDB fibronectin specific peptide for prostate cancer targeting. Bioconjugate Chemistry, 2015, 26(5), 830–838. doi: 10.1021/acs.bioconjchem.5b00178
  65. Medina, S.H.; Schneider, J.P. Cancer cell surface induced peptide folding allows intracellular translocation of drug. Journal of Controlled Release, 2015, 209, 317–326. doi: 10.1016/j.jconrel.2015.05.267
  66. Mwangi, T.K.; Bowles, R.D.; Tainter, D.M.; Bell, R.D.; Kaplan, D.L.; Setton, L.A. Synthesis and characterization of silk fibroin microparticles for intra-articular drug delivery. International Journal of Pharmaceutics, 2015, 485(1–2), 7–14. doi: 10.1016/j.ijpharm.2015.02.059
  67. Wade, R.J.; Bassin, E.J.; Rodell, C.B.; Burdick, J.A. Protease-degradable electrospun fibrous hydrogels. Nature Communications, 2015, 6, 6639. doi: 10.1038/ncomms7639
  68. Bygd, H.C.; Forsmark, K.D.; Bratlie, K.M. Altering in vivo macrophage responses with modified polymer properties. Biomaterials, 2015, 56, 187–197. doi: 10.1016/j.biomaterials.2015.03.042
  69. Deyle, K.M.; Farrow, B.; Hee, Y.Q.; Work, J.; Wong, M.; Lai, B.; Umeda, A.; Millward, S.W.; Nag, A.; Das, S.; Heath, J.R. A protein-targeting strategy used to develop a selective inhibitor of the E17K point mutation in the PH domain of Akt1. Nature Chemistry, 2015, 7, 455–462. doi: 10.1038/nchem.2223
  70. Nikić, I.; Kang, J.H.; Girona, G.E.; Aramburu, I.V.; Lemke, E.A. Labeling proteins on live mammalian cells using click chemistry. Nature Protocols, 2015, 10(5), 780–791. doi: 10.1038/nprot.2015.045
  71. Wang, W.; Kapur, A.; Ji, X.; Safi, M.; Palui, G.; Palomo, V.; Dawson, P.E.; Mattoussi, H. Photoligation of an Amphiphilic Polymer with Mixed Coordination Provides Compact and Reactive Quantum Dots. Journal of the American Chemical Society, 2015, 137(16), 5438–5451. doi: 10.1021/jacs.5b00671
  72. Nåbo, L.J.; Madsen, C.S.; Jensen, K.J.; Kongsted, J.; Astakhova, K. Ultramild Protein-Mediated Click Chemistry Creates Efficient Oligonucleotide Probes for Targeting and Detecting Nucleic Acids. ChemBioChem, 2015, 16(8), 1163–1167. doi: 10.1002/cbic.201500145
  73. Saadat, E.; Shakor, N.; Gholami, M.; Dorkoosh, F.A. Hyaluronic acid based micelle for articular delivery of triamcinolone, preparation, in vitro and in vivo evaluation. International Journal of Pharmaceutics, 2015, 489(1–2), 218–225. doi: 10.1016/j.ijpharm.2015.05.001
  74. Reid, D.A.; Keegan, S.; Leo-Macias, A.; Watanabe, G.; Strande, N.T.; Chang, H.H.; Oksuz, B.A.; Fenyo, D.; Lieber, M.R.; Ramsden, D.A.; Rothenberg, E. Organization and dynamics of the nonhomologous end-joining machinery during DNA double-strand break repair. Proceedings of the National Academy of Sciences of the U.S.A., 2015, 112(20), E2575–E2584. doi: 10.1073/pnas.1420115112
  75. Hou, Z.; Lin, J.; Li, Y.; Guo, F.; Yu, F.; Wu, H.; Fan, Z.; Zhi, L.; Luo, F. Validation of a dual role of methotrexate-based chitosan nanoparticles in vivo. RSC Advances, 2015, 5(52), 41393–41400. doi: 10.1039/c5ra03705K
  76. Ruan, S.; He, Q.; Gao, H. Matrix metalloproteinase triggered size-shrinkable gelatin-gold fabricated nanoparticles for tumor microenvironment sensitive penetration and diagnosis of glioma. Nanoscale, 2015, 7, 9487–9496. doi: 10.1039/c5nr01408e
  77. Shi, Y.; van der Meel, R.; Theek, B.; Oude Blenke, E.; Pieters, E.H.E.; Fens, M.H.A.M.; Ehling, J.; Schiffelers, R.M.; Storm, G.; van Nostrum, C.F.; Lammers, T.; Hennink, W.E. Complete Regression of Xenograft Tumors upon Targeted Delivery of Paclitaxel via Π–Π Stacking Stabilized Polymeric Micelles. ACS Nano, 2015, 9(4), 3740–3752. doi: 10.1021/acsnano.5b00929
  78. Baker, Matthew B. and Albertazzi, Lorenzo and Voets, Ilja K. and Leenders, Christianus M.A. and Palmans, Anja R.A. and Pavan, Giovanni M. and Meijer, E.W. Consequences of chirality on the dynamics of a water-soluble supramolecular polymer. Nature Communications, 2015, 6, 6234. doi: 10.1038/ncomms7234
  79. Rammohan, J.; Ruiz Manzano, A.; Garner, A.L.; Stallings, C.L.; Galburt, E.A. CarD stabilizes mycobacterial open complexes via a two-tiered kinetic mechanism. Nucleic Acids Research, 2015, 43(6), 3272–3285. doi: 10.1093/nar/gkv078
  80. Li, F.; Dong, J.; Hu, X.; Gong, W.; Li, J.; Shen, J.; Tian, H.; Wang, J. A Covalent Approach for Site-Specific RNA Labeling in Mammalian Cells. Angewandte Chemie International Edition, 2015, 54(15), 4597–4602. doi: 10.1002/anie.201410433
  81. Zilio, C.;Bernardi, A.; Palmioli, A.; Salina, M.; Tagliabue, G.; Buscaglia, M.; Consonni, R.; Chiari, M. New "clickable" polymeric coating for glycan microarrays. Sensors and Actuators B: Chemical, 2015, 215, 412–420. doi: 10.1016/j.snb.2015.03.079
  82. Maruani, A.; Smith, M.E.B.; Miranda, E.; Chester, K.A.; Chudasama, V.; Caddick, S. A plug-and-play approach to antibody-based therapeutics via a chemoselective dual click strategy. Nature communications, 2015, 6, 6645. doi: 10.1038/ncomms7645
  83. Arami, H.; Khandhar, A.P.; Tomitaka, A.; Yu, E.; Goodwill, P.W.; Conolly, S.M.; Krishnan, K.M. In vivo multimodal magnetic particle imaging (MPI) with tailored magneto/optical contrast agents. Biomaterials, 2015, 52, 251–261. doi: 10.1016/j.biomaterials.2015.02.040
  84. Huang, J.; Smith, F.; Panizzi, J.R.; Goodwin, D.C.; Panizzi, P. Inactivation of myeloperoxidase by benzoic acid hydrazide. Archives of Biochemistry and Biophysics, 2015, 570, 14–22. doi: 10.1016/j.abb.2015.01.028
  85. Mahoney, D.; Owens, E.A.; Fan, C.; Hsiang, J.-C.; Henary, M.; Dickson, R.M. Tailoring Cyanine Dark States for Improved Optically Modulated Fluorescence Recovery. The Journal of Physical Chemistry B, 2015, 119(13), 4637–4643. doi: 10.1021/acs.jpcb.5b00777
  86. Rodell, C.B.; Wade, R.J.; Purcell, B.P.; Dusaj, N.N.; Burdick, J.A. Selective Proteolytic Degradation of Guest–Host Assembled, Injectable Hyaluronic Acid Hydrogels. ACS Biomaterials Science & Engineering, 2015, 1(4), 277–286. doi: 10.1021/ab5001673
  87. Rodell, C.B.; Rai, R.; Faubel, S.; Burdick, J.A.; Soranno, D.E. Local Immunotherapy via Delivery of Interleukin-10 and Transforming Growth Factor β Antagonist for Treatment of Chronic Kidney Disease. Journal of Controlled Release, 2015, 206, 131–139. doi: 10.1016/j.jconrel.2015.03.025
  88. Hörner, A.; Hagendorn, T.; Schepers, U.; Bräse, S. Photophysical properties and synthesis of new dye-cyclooctyne conjugates for multicolor and advanced microscopy. Bioconjugate Chemistry, 2015, 26(4), 718–724. doi: 10.1021/acs.bioconjchem.5b00059
  89. Leonard, J.D.; Narlikar, G.J. A Nucleotide-Driven Switch Regulates Flanking DNA Length Sensing by a Dimeric Chromatin Remodeler. Molecular Cell, 2015, 57(5), 850–859. doi: 10.1016/j.molcel.2015.01.008
  90. Kim, M.-G.; Park, J.Y.; Miao, W.; Lee, J.; Oh, Y.-K. Polyaptamer DNA nanothread-anchored, reduced graphene oxide nanosheets for targeted delivery. Biomaterials, 2015, 48, 129–136. doi: 10.1016/j.biomaterials.2015.01.009
  91. Lee, S.J.; Shim, Y.H.; Oh, J.-S.; Jeong, Y.-I. Park, I.-K.; Lee, H.C. Folic-acid-conjugated pullulan/poly(DL-lactide-co-glycolide) graft copolymer nanoparticles for folate-receptor-mediated drug delivery. Nanoscale Research Letters, 2015, 10, 43. doi: 10.1186/s11671-014-0706-1
  92. Ashoub, A.; Baeumlisberger, M.;Neupaertl, M.; Karas, M.; Brüggemann, W. Characterization of common and distinctive adjustments of wild barley leaf proteome under drought acclimation, heat stress and their combination. Plant Molecular Biology, 2015, 87(4–5), 459–471. doi: 10.1007/s11103-015-0291-4
  93. Cai, H.; Singh, A.N.; Sun, X.; Peng, F. Synthesis and Characterization of Her2-NLP Peptide Conjugates Targeting Circulating Breast Cancer Cells: Cellular Uptake and Localization by Fluorescent Microscopic Imaging. Journal of Fluorescence, 2015, 25(1), 113–117. doi: 10.1007/s10895-014-1486-9
  94. Yang, Q.; Li, L.; Zhu, X.; Sun, W.; Zhou, Z.; Huang, Y. The impact of the HPMA polymer structure on the targeting performance of the conjugated hydrophobic ligand. RSC Advances, 2015, 5(19), 14858–14870. doi: 10.1039/c4ra16085a
  95. Aldeek, F.; Hawkins, D.; Palomo, V.; Safi, M.; Palui, G.; Dawson, P.E.; Alabugin, I.V.; Mattoussi, H. UV and Sunlight Driven Photoligation of Quantum Dots: Understanding the Photochemical Transformation of the Ligands. Journal of the American Chemical Society, 2015, 137(7), 2704–2714. doi: 10.1021/ja512802x
  96. Cai, L.; Dewi, R.E.; Heilshorn, S.C. Injectable Hydrogels with In Situ Double Network Formation Enhance Retention of Transplanted Stem Cells. Advanced Functional Materials, 2015, 25(9), 1344–1351. doi: 10.1002/adfm.201403631
  97. Duong, H.T.T.; Dong, Z.; Su, L; Boyer, C.; George, J.; Davis, T.P.; Wang, J. The Use of Nanoparticles to Deliver Nitric Oxide to Hepatic Stellate Cells for Treating Liver Fibrosis and Portal Hypertension. Small, 2015, 11(19), 2291–2304. doi: 10.1002/smll.201402870
  98. Pereira, P.M.; Almada, P.; Henriques, R. High-content 3D multicolor super-resolution localization microscopy. Methods in Cell Biology, 2015, 125, 95–117. doi: 10.1016/bs.mcb.2014.10.004
  99. Glembockyte, V.; Lincoln, R.; Cosa, G. Cy3 Photoprotection Mediated by Ni2+ for Extended Single-Molecule Imaging: Old Tricks for New Techniques. Journal of the American Chemical Society, 2015, 137(3), 1116–1122. doi: 10.1021/ja509923e
  100. Wen, A.M.; Infusino, M.; De Luca, A.; Kernan, D.L.; Czapar, A.E.; Strangi, G.; Steinmetz, N.F. Interface of Physics and Biology: Engineering Virus-Based Nanoparticles for Biophotonics. Bioconjugate Chemistry, 2015, 26(1), 51–62. doi: 10.1021/bc500524f
  101. Nakamura, T.; Sugihara, F.; Matsushita, H.; Yoshioka, Y.; Mizukami, S.; Kikuchi, K. Mesoporous silica nanoparticles for 19F magnetic resonance imaging, fluorescence imaging, and drug delivery. Chemical Science, 2015, 6, 1986–1990. doi: 10.1039/c4sc03549f
  102. Brauer, V.S.; Stomp, M.; Bouvier, T.; Fouilland, E.; Leboulanger, C.; Confurius-Guns, V.; Weissing, F.J.; Stal, L.J.; Huisman, J. Competition and facilitation between the marine nitrogen-fixing cyanobacterium Cyanothece and its associated bacterial community. Frontiers in Microbiology, 2015, 5, 795. doi: 10.3389/fmicb.2014.00795
  103. Zhang, J.; Wang, G.; Mao, D.; Han, A.; Xiao, N.; Qi, X.; Ding, D.; Kong, D. Targeted In Vivo Imaging of Mouse Hindlimb Ischemia Using Fluorescent Gelatin Nanoparticles. Journal of Nanomaterials, 2015, 2015, Article ID 704817. doi: doi.org/10.1155/2015/704817
  104. Hsueh, P.-Y.; Edman, M.C.; Sun, G.; Shi, P.; Xu, S.; Lin, Y.-a.; Cui, H.; Hamm-Alvarez, S.F.; MacKay, J.A. Tear-mediated delivery of nanoparticles through transcytosis of the lacrimal gland. Journal of Controlled Release, 2015, 208, 2–13. doi: 10.1016/j.jconrel.2014.12.017
  105. Chiang, W.-L.; Lin, T.-T.; Sureshbabu, R.; Chia, W.-T.; Hsiao, H.-C.; Liu, H.-Y.; Yang, C.-M.; Sung, H.-W. A rapid drug release system with a NIR light-activated molecular switch for dual-modality photothermal/antibiotic treatments of subcutaneous abscesses. Journal of Controlled Release, 2015, 199, 53–62. doi: 10.1016/j.jconrel.2014.12.011
  106. Popp, M.W. Site-Specific Labeling of Proteins via Sortase: Protocols for the Molecular Biologist. Methods in Molecular Biology, 2015, 1266, 185–198. doi: 10.1007/978-1-4939-2272-7_13
  107. Choi, E.B.; Choi, J.; Bae, S.R.; Kim, H.-O.; Jang, E.; Kang, B.; Kim, M.-H.; Kim, B.; Suh, J.-S.; Lee, K. et al. Colourimetric redox-polyaniline nanoindicator for in situ vesicular trafficking of intracellular transport. Nano Research, 2015, 8(4), 1169–1179. doi: 10.1007/s12274-014-0597-6
  108. Maruani, A.; Alom, S.; Canavelli, P.; Lee, M.T.W.; Morgan, R.E.; Chudasama, V.; Caddick, S. A mild TCEP-based para-azidobenzyl cleavage strategy to transform reversible cysteine thiol labelling reagents into irreversible conjugates. Chemical Communications, 2015, 51, 5279–5282. doi: 10.1039/c4cc08515a
  109. Geertsema, H.J.; Duderstadt, K.E.; van Oijen, A.M. Single-molecule observation of prokaryotic DNA replication. Methods in Molecular Biology, 2015, 1300, 219–238. doi: 10.1007/978-1-4939-2596-4_14
  110. Wei, S.; Shalhout, S.; Ahn, Y.-H.; Bhagwat, A.S. A Versatile New Tool to Quantify Abasic Sites in DNA and Inhibit Base Excision Repair. DNA Repair, 2015, 27, 9–18. doi: doi:10.1016/j.dnarep.2014.12.006
  111. Jeong, J.-H. Molecular imaging monitoring of poly(ethylene glycol) conjugated islets for evaluation of islet graft rejection. Archives of Pharmacal Research, 2015, 38(5), 785–790. doi: 10.1007/s12272-014-0412-7
  112. Nooney, R.I.; White, A.; O’Mahony, C.; O’Connell, C.; Kelleher, S.M.; Daniels, S.; McDonagh, C. Investigating the colloidal stability of fluorescent silica nanoparticles under isotonic conditions for biomedical applications. Journal of Colloid and Interface Science, 2015, 456, 50–58. doi: 10.1016/j.jcis.2015.05.051
  113. Guenther, D.; Anderson, G.; Karmakar, S.; Anderson, B.A.; Didion, B.A.; Guo, W.; Verstegen, J.; Hrdlicka, P.J. Invader probes: Harnessing the energy of intercalation to facilitate recognition of chromosomal DNA for diagnostic applications. Chemical Science, 2015, 6, 5006–2015. doi: 10.1039/c5sc01238d
  114. Nooney, R.; O’Connell, C.; Roy, S.; Boland, K.; Keegan, G.; Kelleher, S.; Daniels, S.; McDonagh, C. Synthesis and characterisation of far-red fluorescent cyanine dye doped silica nanoparticles using a modified microemulsion method for application in bioassays. Sensors and Actuators B: Chemical, 2015, 221, 470–479. doi: 10.1016/j.snb.2015.06.117
  115. Lipchik, A.M.; Perez, M.; Cui, W.; Parker, L.L. Multicolored, Tb3+-Based Antibody-Free Detection of Multiple Tyrosine Kinase Activities. Analytical Chemistry, 2015, 87(15), 7555–7558. doi: 10.1021/acs.analchem.5b02233
  116. Tucker, K.R.; Block, E.R.; Levitan, E.S. Action potentials and amphetamine release antipsychotic drug from dopamine neuron synaptic VMAT vesicles. Proceedings of the National Academy of Sciences of the U.S.A., 2015, 112(32), E4485–E4494. doi: 10.1073/pnas.1503766112
  117. Zhang, Z.; Kenny, S.J.; Hauser, M.; Li, W.; Xu, K. Ultrahigh-throughput single-molecule spectroscopy and spectrally resolved super-resolution microscopy. Nature Methods, 2015, 12(10), 935–938. doi: 10.1038/nmeth.3528
  118. Martell, D.J.; Joshi, C.P.; Gaballa, A.; Santiago, A.G.; Chen, T.-Y.; Jung, W.; Helmann, J.D.; Chen, P. Metalloregulator CueR biases RNA polymerase's kinetic sampling of dead-end or open complex to repress or activate transcription. Proceedings of the National Academy of Sciences of the U.S.A., 2015, 112(44), 13467–13472. doi: 10.1073/pnas.1515231112
  119. Chen, K.; Xu, X.; Guo, J.W.; Zhang, X.; Han, S.; Wang, R.; Li, X.; Zhang, J. Enhanced Intracellular Delivery and Tissue Retention of Nanoparticles by Mussel-Inspired Surface Chemistry. Biomacromolecules, 2015, 16(11), 3574–3583. doi: 10.1021/acs.biomac.5b01056
  120. Einfalt, T.; Goers, R.; Dinu, I.A.; Najer, A.; Spulber, M.; Onaca-Fischer, O.; Palivan, C.G. Stimuli-triggered activity of nanoreactors by biomimetic engineering polymer membranes. Nano Letters, 2015, 15(11), 7596–7603. doi: 10.1021/acs.nanolett.5b03386
  121. Mohan, K.; Weiss, G.A. Engineering chemically modified viruses for prostate cancer cell recognition. Molecular BioSystems, 2015, 11, 3264–3272. doi: 10.1039/c5mb00511f
  122. Junker, M.; Rapoport, T.A. Involvement of VAT-1 in phosphatidylserine transfer from the endoplasmic reticulum to mitochondria. Traffic, 2015, 16(12), 1306–1317. doi: 10.1111/tra.12336
  123. Santangelo, M.F.; Sciuto, E.L.; Busacca, A.C.; Petralia, S.; Conoci, S.; Libertino, S. SiPM as miniaturised optical biosensor for DNA-microarray applications. Sensing and Bio-Sensing Research, 2015, 6, 95–98. doi: 10.1016/j.sbsr.2015.08.003
  124. Sciuto, E.L.; Santangelo, M.F.; Villaggio, G.; Sinatra, F.; Bongiorno, C.; Nicotra, G.; Libertino, S. Photo-physical characterization of fluorophore Ru(bpy)32+ for optical biosensing applications. Sensing and Bio-Sensing Research, 2015, 6, 67–71. doi: 10.1016/j.sbsr.2015.09.003
  125. Dogandzhiyski, P.; Ghidini, A.; Danneberg, F.; Strömberg, R.; Göbel, M.W. Studies on Tris(2-aminobenzimidazole)-PNA Based Artificial Nucleases: A Comparison of Two Analytical Techniques. Bioconjugate Chemistry, 2015, 26(12), 2514–2519. doi: 10.1021/acs.bioconjchem.5b00534

2014

  1. Hickey, S. F.; Hammond, M.C. Structure-Guided Design of Fluorescent S-Adenosylmethionine Analogs for a High-Throughput Screen to Target SAM-I Riboswitch RNAs. Chemistry & Biology, 2014, 21(3), 345–356. doi: 10.1016/j.chembiol.2014.01.004
  2. Wang, X.; Huang, S.S.; Heston, W.D.W.; Guo, H.; Wang, B.-C.; Basilion, J.P. Development of Targeted Near-Infrared Imaging Agents for Prostate Cancer. Molecular Cancer Therapeutics, 2014, 13(11), 2595–2606. doi: 10.1158/1535-7163.mct-14-0422
  3. Shieh, P.; Siegrist, M.S.; Cullen, A.J.; Bertozzi, C.R. Imaging bacterial peptidoglycan with near-infrared fluorogenic azide probes. Proceedings of the National Academy of Sciences of the U.S.A., 2014, 111(15), 5456–5461. doi: 10.1073/pnas.1322727111
  4. Bird, G.H., Boyapalle, S.; Wong, T.; Opoku-Nsiah, K.; Bedi, R.; Crannell, W.C.; Perry, A.F.; Nguyen, H.; Sampayo, V.; Devareddy, A.; Mohapatra, S.; Mohapatra S.S.; Walensky, L.D. Mucosal delivery of a double-stapled