Список цитирований

Список публикаций, цитирующих продукты Lumiprobe. Публикации можно отсортировать по дате или по продукту.

В печати

  1. Liu, L.; Li, X.; Wu, Z.; Yang, L.; Huo, J.; Tang, S.; Cao, X.; Xu, Y.; Liao, X.; Qi, H.; Li, J.; Liu, J.; Tian, J.; Wen, R.; Wang, C.; Bai, C. Inflammation-targeting Fullerene Nanoparticles Dually Inhibit Macrophage and Osteoclast Differentiation for Mitigating Rheumatoid Arthritis. CCS Chemistry, 2024, 1-63. doi: 10.31635/ccschem.023.202303517
  2. Thi Duy Ngoc, N.; Yurchenko, E. A.; Thi Hoai Trinh, P.; Menchinskaya, E. S.; Thi Dieu, T. V.; Savagina, A. D.; Minin, A.; Thinh, P. D.; Khanh, H. H. N.; Thi Thanh Van, T.; Yurchenko, A. N. Secondary Metabolites of Vietnamese Marine Fungus Penicillium Chermesinum 2104NT-1.3 and Their Cardioprotective Activity. Regional Studies in Marine Science, 2024, 104003. doi: 10.1016/j.rsma.2024.104003

Предпечатное издание

  1. Omweri, J.M.; Houson, H.A.; Lynch, S.E.; Tekin, V.; Sorace, A.G.; Lapi, S.E. PET imaging of [52 Mn]Mn-DOTATATE and [52 Mn]Mn-DOTA-JR11. Research Square, 2024, preprint. doi: 10.21203/rs.3.rs-4684098/v1
  2. Gorshkova, M.; Vanchugova, L.; Osipova, N.; Nikitin, A.; Kotova, J.; Kovalenko, E.; Ermolenko, Y.; Malinovskaya, J.; Kovshova, T.; Gelperina, S. Hybrid DIVEMA/PLGA nanoparticles as the potential drug delivery system. Research Square, 2024, preprint. doi: 10.21203/rs.3.rs-4594368/v1
  3. Frazier, C.L.; Deb, D.; Weeks, A.M. Engineered reactivity of a bacterial E1-like enzyme enables ATP-driven modification of protein C termini. bioRxiv, 2024, preprint. doi: 10.1101/2024.05.13.593989
  4. Petrov, S.A.; Grigoriev, G.P.; Orlov, G.А.; Zyk, N.Y.; Grishin, Y.K.; Roznyatovsky, V.A.; Beloglazkina, M.A.; Kuznetsova, J.V.; Machulkin, A.E.; Beloglazkina, E.K. Routes to PSMA/GRPr Targeted Heterobivalent Conjugates: Synthetic Strategies and Their Evaluation. Preprints, 2024, preprint. doi: 10.20944/preprints202405.0810.v1
  5. Chandler, T.; Guo, M.; Su, Y.; Chen, J.; Wu, Y.; Liu, J.; Agashe, A.; Fischer, R.S.; Mehta, S.B.; Kumar, A.; Baskin, T.I.; Jamouillé, V.; Liu, H.; Swaminathan, V.; Nain, A.; Oldenbourg, R.; Riviére, P.L.; Shroff, H. Three-dimensional spatio-angular fluorescence microscopy with a polarized dual-view inverted selective-plane illumination microscope (pol-diSPIM). bioRxiv, 2024, preprint. doi: 10.1101/2024.03.09.584243
  6. Henry, W.S.; Müller, S.; Yang, J.-S.; Innes-Gold, S.; Das, S.; Reinhardt, F.; Sigmund, K.; Phadnis, V.V.; Wan, Z.; Eaton, E.; Sampaio, J.L.; Bell, G.W.; Viravalli, A.; Hammond, P.T.; Kamm, R.D.; Cohen, A.E.; Boehnke, N.; Hsu, V.W.; Levental, K.R.; Rodriguez, R.; Weinberg, R.A. Ether lipids influence cancer cell fate by modulating iron uptake. bioRxiv, 2024, preprint. doi: 10.1101/2024.03.20.585922
  7. Oh, H.J.; Lee, Y.; Hwang, H.; Hong, K.; Choi, H.; Kang, J.Y.; Jung, Y. Size-controlled synthesis of phase separated protein condensates with interfacial protein cages. chemRxiv, 2024, preprint. doi: 10.26434/chemrxiv-2024-nkftl
  8. Damm, A.; Paik, S.-J.; Sadhu, R.K.; Di-Cicco, A.; Manzi, J.; Castellana, M.; Margeat, E.; Dahan, M.; Sens, P.; Lévy, D.; Bassereau, P. Mechanosensitivity of an ABC Membrane Transporter Revealed by Single Molecule FRET and Activity Measurement. bioRxiv, 2024, preprint. doi: 10.1101/2024.01.24.577054
  9. Fischer, J.M.; Stewart, M.; Dai, M.; Drennan, S.; Holland, S.; Quentel, A.; Sabuncu, S.; Kingston, B.R.; Dengos, I.; Xiang, L.; Bonic, K.; Goncalves, F.; Yi, X.; Ranganathan, S.; Branchaud, B.P.; Muldoon, L.L.; Barajas, R.F.; Yildirim, A. Peptide Amphiphiles Hitchhike on Endogenous Biomolecules for Enhanced Cancer Imaging and Therapy. bioRxiv, 2024, preprint. doi: 10.1101/2024.02.21.580762
  10. Schöpf, F.; Marongiu, G.L.; Milaj, K.; Sprink, T.; Kikhney, J.; Moter, A.; Roderer, D. Structural basis of Fusobacterium nucleatumadhesin Fap2 interaction with receptors on cancer and immune cells. bioRxiv, 2024, preprint. doi: 10.1101/2024.02.28.582045
  11. Uckelmann, M.; Levina, V.; Taveneau, C.; Han Ng, X.; Pandey, V.; Martinez, J.; Mendiratta, S.; Houx, J.; Boudes, M.; Venugopal, H.; Trépout, S.; Zhang, Q.; Flanigan, S.; Li, M.; Sierecki, E.; Gambin, Y.; Das, P.P.; Bell, O.; de Marco, A.; Davidovich, C. Dynamic PRC1-CBX8 stabilizes a porous structure of chromatin condensates. bioRxiv, 2024, preprint. doi: 10.1101/2023.05.08.539931
  12. Murali, V.S.; Rajendran, D.; Isogai, T.; DeBerardinis, R.J.; Danuser, G. RhoA activation promotes glucose uptake to elevate proliferation in MAPK inhibitor resistant melanoma cells. bioRxiv, 2024, preprint. doi: 10.1101/2024.01.09.574940
  13. Hossain, K.; Smith, M.; Santoro, S.W. In mice, discrete odors can selectively promote the neurogenesis of sensory neuron subtypes that they stimulate. bioRxiv, 2024, preprint. doi: 10.1101/2024.02.10.579748
  14. Borisenko, I.; Predeus, A.; Lavrov, A.; Ereskovsky, A. First draft genome assembly and characterization of sponge Halisarca dujardinii reveals key components of basement membrane and broad repertoire of aggregation factors. bioRxiv, 2024, preprint. doi: 10.1101/2024.02.06.578935
  15. Kalinina, A.; Dhaliwal, J.; Xue, Y.; Vaculik, M.; McCambley, M.; Fong, B.C.; Cook, D.; Slack, R.S.; Lagace, D.C. Mitotic Activity and DNA Maintenance of Adult Neural Stem Cells is Regulated by Beclin1. bioRxiv, 2024, preprint. doi: 10.1101/2024.01.26.573092
  16. Rahni, R.; Guillotin, B.; Lee, L.R.; Birnbaum, K.D. A temporal map of division, chromatin modification, and identity specification in the regenerating root. bioRxiv, 2024, preprint. doi: 10.1101/2024.01.09.574680
  17. Huang, L.; Liu, P.; Du, Y.; Pan, D.; Lee, A.; Wolfe, S.A.; Wang, Y.-X. A brown fat-enriched adipokine, ASRA, is a leptin receptor antagonist that stimulates appetite. bioRxiv, 2024, preprint. doi: 10.1101/2023.09.12.557454
  18. Feng, X. A.; Yamadi, M.; Fu, Y.; Ness, K. M.; Liu, C.; Ahmed, I.; Bowman, G. D.; Johnson, M. E.; Ha, T.; Wu, C. GAGA zinc finger transcription factor searches chromatin by 1D-3D facilitated diffusion. bioRxiv, 2024, preprint. doi: 10.1101/2023.07.14.549009

2025

  1. Pislyagin, E. A.; Tarbeeva, D. V.; Yurchenko, E. A.; Menchinskaya, E. S.; Gorpenchenko, T. Y.; Pokhilo, N. D.; Kalinovskiy, A. I.; Aminin, D. L.; Fedoreyev, S. A. Neuroprotective Activity of Oligomeric Stilbenes from Alpha Grape Stems in In Vitro Models of Parkinson’s Disease. International Journal of Molecular Sciences, 2025, 26(6), 2411. doi: 10.3390/ijms26062411

2024

  1. Tchatchiashvilli, T.; Duering, H.; Mueller-Boetticher, L.; Grune, C.; Fischer, D.; Pletz, M.W.; Makarewicz, O. PEG-PLGA nanoparticles deposited in Pseudomonas aeruginosa and Burkolderia cenocepacia. Journal of Pharmaceutical Analysis, 2024, 14(12), 100939. doi: 10.1016/j.jpha.2024.01.007
  2. Johnson, J.L.; Steele, J.H.; Lin, R.; Stepanov, V.G.; Gavriliuc, M.N.; Wang, Y. Multi-Channel smFRET study reveals a Compact conformation of EF-G on the Ribosome. bioRxiv, 2024, preprint. doi: 10.1101/2024.01.27.577133
  3. Solé‐Porta, A.; Areny‐Balagueró, A.; Camprubí‐Rimblas, M.; Fernández Fernández, E.; O’Sullivan, A.; Giannoccari, R.; MacLoughlin, R.; Closa, D.; Artigas, A.; Roig, A. Efficient Nebulization and Pulmonary Biodistribution of Polymeric Nanocarriers in an Acute Lung Injury Preclinical Model. Small Science, 2024, 4(9), 2400066. doi: 10.1002/smsc.202400066
  4. Song, X.; Jin, J.; Yin, H.; Wang, T.; Zong, H.; Wang, F.; Liu, J.; Huang, X.; Wang, B.; Chai, C.; Li, Z.; Liu, D.; Wang, X.; Song, N. Trichoderma Viride F7 Improves Peanut Performance While Remedying Cadmium-Contaminated Soil with Microplastics. Pedosphere, 2024, 34(5), 971-980. doi: 10.1016/j.pedsph.2023.06.010
  5. Zhang, Y.; Liang, L.; Li, H.; Cao, Y.; Meng, D.; Li, X.; Wang, M.; Wang, J.; Yao, Y.; Zhang, S.; Chen, C.; Hou, P.; Yang, Q. Smart multi‐functional aggregates reoxygenate tumor microenvironment through a two‐pronged strategy to revitalize cancer immunotherapy. Aggregate, 2024, 5(4), e545. doi: 10.1002/agt2.545
  6. Kim, R.; Allbritton, N.L. A Microphysiological System with an Anaerobic Air‐Liquid Interface and Functional Mucus Layer for Coculture of Intestinal Bacteria and Primary Human Colonic Epithelium. Advanced Materials Interfaces, 2024, 11(25), 2400093. doi: 10.1002/admi.202400093
  7. Legen, J.; Lenzen, B.; Kachariya, N.; Feltgen, S.; Gao, Y.; Mergenthal, S.; Weber, W.; Klotzsch, E.; Zoschke, R.; Sattler, M.; Schmitz-Linneweber, C. A prion-like domain is required for phase separation and chloroplast RNA processing during cold acclimation in Arabidopsis. The Plant Cell, 2024, 36(8), koae145. doi: 10.1093/plcell/koae145
  8. Kim, D.; Whang, C.‐H.; Hong, J.; Prayogo, M.C.; Jung, W.; Lee, S.; Shin, H.; Kim, Y.; Yu, J.; Kim, M.J.; Kim, K.; Lee, H.‐S.; Jon, S. Glycocalyx‐Mimicking Nanoparticles with Differential Organ Selectivity for Drug Delivery and Therapy. Advanced Materials, 2024, 36(27), 2311283. doi: 10.1002/adma.202311283
  9. Proksch, J.; Dal Colle, M. C. S.; Heinz, F.; Schmidt, R. F.; Gottwald, J.; Delbianco, M.; Keller, B. G.; Gradzielski, M.; Alexiev, U.; Koksch, B. Impact of Glycan Nature on Structure and Viscoelastic Properties of Glycopeptide Hydrogels. Journal of Peptide Science, 2024, 30(8), e3599. doi: 10.1002/psc.3599
  10. Piranej, S.; Zhang, L.; Bazrafshan, A.; Marin, M.; Melikian, G. B.; Salaita, K. Rolosense: Mechanical Detection of SARS-CoV-2 Using a DNA-Based Motor. ACS Cent. Sci., 2024, 10(7), 1332–1347. doi: 10.1021/acscentsci.4c00312
  11. Wu, X.; Babi, M.; Moran-Mirabal, J.; Pelton, R. H. Grafting Polyanhydride Polymers to Cellulose Nanofibers. Cellulose, 2024, 31, 6193–6210. doi: 10.1007/s10570-024-05977-8
  12. Spoelstra, G.B.; Blok, S.N.; Reali Nazario, L.; Noord, L.; Fu, Y.; Simeth, N.A.; IJpma, F.F.A.; van Oosten, M.; van Dijl, J.M.; Feringa, B.L.; Szymanski, W.; Elsinga, P.H. Synthesis and preclinical evaluation of novel 18F-vancomycin-based tracers for the detection of bacterial infections using positron emission tomography. European Journal of Nuclear Medicine and Molecular Imaging, 2024, 51, 2583–2596. doi: 10.1007/s00259-024-06717-7
  13. Jurczak, P.; Fayad, N.; Benard, M.; Czaplewska, P.; Hildebrandt, N. Monomer‐dimer equilibrium of human cystatin C during internalization into cancer cells. ChemBioChem, 2024, 25(16), e202400226. doi: 10.1002/cbic.202400226
  14. Kaneda, K.; Takeuchi, Y.; Yamanaka, K.; Hasebe, F.; Maruyama, C.; Hamano, Y. Cell-penetrating activity of a short-chain ε-poly-l-α-lysine. Journal of Bioscience and Bioengineering, 2024, 138(3), 249-253. doi: 10.1016/j.jbiosc.2024.06.006
  15. Skorobogatov, E. V.; Shik, A. V.; Sobolev, P. V.; Stepanova, I. A.; Orekhov, V. S.; Ustyuzhanin, A. O.; Koksharova, M. V.; Ikhalaynen, Y. A.; Timchenko, Y. V.; Rodin, I. A.; Beklemishev, M. K. Monitoring Different Water Types for Engine Oil–Water-Soluble Fraction and Iron(2+) Using a Reaction-Based Optical Sensing Strategy: A Proof-of-Concept Study. Ind. Eng. Chem. Res., 2024, 63(28), 12336–12349. doi: 10.1021/acs.iecr.4c01502
  16. Campea, M. A.; Macdonald, C.; Hoare, T. Supramolecularly-Cross-Linked Nanogel Assemblies for On-Demand, Ultrasound-Triggered Chemotherapy. Biomacromolecules, 2024. doi: 10.1021/acs.biomac.3c01432
  17. Krause, K. D.; Rees, K.; Darwish, G. H.; Bernal-Escalante, J.; Algar, W. R. Bait and Cleave: Exosite-Binding Peptides on Quantum Dots Selectively Accelerate Protease Activity for Sensing with Enhanced Sensitivity. ACS Nano, 2024, 18(26), 17018–17030. doi: 10.1021/acsnano.4c03265
  18. Schvartzman, C.; Ibarboure, E.; Martin, A.; Garanger, E.; Mutschler, A.; Lecommandoux, S. Protocells Featuring Membrane-Bound and Dynamic Membraneless Organelles. Biomacromolecules, 2024, 25(7), 4087–4094. doi: 10.1021/acs.biomac.4c00200
  19. Yu, J.; Ma, Y.; Zhang, X.; Wang, S.; Zhou, L.; Liu, X.; Li, L.; Liu, L.; Song, H.; Luo, Y.; Wen, S.; Li, W.; Niu, X. β-Cyclodextrin and Hyaluronic Acid-Modified Targeted Nanodelivery System for Atherosclerosis Prevention. ACS Appl. Mater. Interfaces, 2024, 16(27), 35421–35437. doi: 10.1021/acsami.4c01540
  20. Park, B.; Han, G.; Jin, D. Y.; Gil, K. C.; Shin, D.; Lee, J.; Park, J. Y.; Jang, H.; Park, D.; Lee, S.; Kim, K.; Yang, Y.; Kim, Y.; Kim, J.-S.; Kim, S. H.; Shim, M. K. Mucoadhesive Mesalamine Prodrug Nanoassemblies to Target Intestinal Macrophages for the Treatment of Inflammatory Bowel Disease. ACS Nano, 2024, 18(25), 16297–16311. doi: 10.1021/acsnano.4c05544
  21. Comeo, E.; Goulding, J.; Lin, C.-Y.; Groenen, M.; Woolard, J.; Kindon, N. D.; Harwood, C. R.; Platt, S.; Briddon, S. J.; Kilpatrick, L. E.; Scammells, P. J.; Hill, S. J.; Kellam, B. Ligand-Directed Labeling of the Adenosine A1 Receptor in Living Cells. J. Med. Chem., 2024, 67(14), 12099–12117. doi: 10.1021/acs.jmedchem.4c00835
  22. Chen, J.; Li, F.; Zhao, B.; Gu, J.; Brejcha, N. M.; Bartoli, M.; Zhang, W.; Zhou, Y.; Fu, S.; Domena, J. B.; Zafar, A.; Zhang, F.; Tagliaferro, A.; Verde, F.; Zhang, F.; Zhang, Y.; Leblanc, R. M. Gene Transfection Efficiency Improvement with Lipid Conjugated Cationic Carbon Dots. ACS Appl. Mater. Interfaces, 2024, 16(21), 27087–27101. doi: 10.1021/acsami.4c02614
  23. Kim, S. H.; Chun, C.; Yoon, T.-Y. Profiling of BCLxL Protein Complexes in Non-Small Cell Lung Cancer Cells via Multiplexed Single-Molecule Pull-Down and Co-Immunoprecipitation. Anal. Chem., 2024, 96(22), 8932–8941. doi: 10.1021/acs.analchem.3c05801
  24. Huynh, G. T.; Tunny, S. S.; Frith, J. E.; Meagher, L.; Corrie, S. R. Organosilica Nanosensors for Monitoring Spatiotemporal Changes in Oxygen Levels in Bacterial Cultures. ACS Sens., 2024, 9(5), 2383–2394. doi: 10.1021/acssensors.3c02747
  25. Zeng, Z.; Tan, R.; Chen, S.; Chen, H.; Liu, Z.; Liu, L.; Li, M.; Chen, Y. Di-PEGylated insulin: A long-acting insulin conjugate with superior safety in reducing hypoglycemic events. Acta Pharmaceutica Sinica B, 2024, 14(6), 2761-2772. doi: 10.1016/j.apsb.2024.02.022
  26. Lee, W.; Lim, Y.G.; Song, Y.J.; Park, K. Intracellular cholesterol efflux effects of mannose-beta cyclodextrin conjugates on cholesterol-laden foam cells. Biotechnology and Bioprocess Engineering, 2024, 29, 483–493. doi: 10.1007/s12257-024-00101-w
  27. Grosmanová, E.; Pola, R.; Filipová, M.; Henry, M.; Coll, J.‐L.; Etrych, T. Novel strategies for enhanced fluorescence visualization of glioblastoma tumors based on HPMA copolymers conjugated with tumor targeting and/or cell‐penetrating peptides. VIEW, 2024, 5(3), 20230116. doi: 10.1002/viw.20230116
  28. Timchenko, A.I.; Simakova, U.V.; Portnova, D.A. Morphological and genetic diversity of ice-associated nematodes of the family Xyalidae Chitwood, 1951. Polar Biology, 2024, 47, 569–587. doi: 10.1007/s00300-024-03245-w
  29. Lin, C.; Cheng, T.-M.; Liu, Y.-C.; Hsu, F.-Y.; Shih, C.-M.; Tsai, M.-L.; Shih, C.-C.; Mi, F.-L. Dual-Targeting EGCG/NO-Supplying protein assembled nanoparticles with Multi-Synergistic effects against atherosclerosis. Chemical Engineering Journal, 2024, 493, 152755. doi: 10.1016/j.cej.2024.152755
  30. Karan, S.; Durán-Meza, A. L.; Chapman, A.; Tanimoto, C.; Chan, S. K.; Knobler, C. M.; Gelbart, W. M.; Steinmetz, N. F. In Vivo Delivery of Spherical and Cylindrical In Vitro Reconstituted Virus-like Particles Containing the Same Self-Amplifying MRNA. Mol. Pharmaceutics, 2024, 21(6), 2727–2739. doi: 10.1021/acs.molpharmaceut.3c01105
  31. Huang, Y.; Osouli, A.; Pham, J.; Mancino, V.; O’Grady, C.; Khan, T.; Chaudhuri, B.; Pastor-Soler, N. M.; Hallows, K. R.; Chung, E. J. Investigation of Basolateral Targeting Micelles for Drug Delivery Applications in Polycystic Kidney Disease. Biomacromolecules, 2024, 25(5), 2749–2761. doi: 10.1021/acs.biomac.3c01397
  32. Sun, B.; Yang, H.; Li, Y.; Scheerstra, J. F.; van Stevendaal, M. H. M. E.; Li, S.; van Hest, J. C. M. Targeted PH-Activated Peptide-Based Nanomaterials for Combined Photodynamic Therapy with Immunotherapy. Biomacromolecules, 2024, 25(5), 3044–3054. doi: 10.1021/acs.biomac.4c00141
  33. Mazrad, Z. A. I.; Refaat, A.; Morrow, J. P.; Voelcker, N. H.; Nicolazzo, J. A.; Leiske, M. N.; Kempe, K. Folic Acid-Conjugated Brush Polymers Show Enhanced Blood–Brain Barrier Crossing in Static and Dynamic In Vitro Models Toward Brain Cancer Targeting Therapy. ACS Biomater. Sci. Eng., 2024, 10(5), 2894–2910. doi: 10.1021/acsbiomaterials.3c01650
  34. Jensen, M.; Stenfelt, L.; Ricci Hagman, J.; Pichler, M.J.; Weikum, J.; Nielsen, T.S.; Hult, A.; Morth, J.P.; Olsson, M.L.; Abou Hachem, M. Akkermansia muciniphila exoglycosidases target extended blood group antigens to generate ABO-universal blood. Nature Microbiology, 2024, 9, 1176–1188. doi: 10.1038/s41564-024-01663-4
  35. Breusa, S.; Thomas, E.; Baldinotti, N.; Zilio, S.; Delcros, J.-G.; Hernandez-Palomino, D.M.; Qi, W.; Guerin, H.; Gibert, B.; Mehlen, P.; Marigo, I.; Kryza, D.; Lollo, G. Anti-Netrin-1 decorated nanoparticles combined with chemotherapy for the treatment of triple-negative breast cancer. Biomaterials Advances, 2024, 161, 213881. doi: 10.1016/j.bioadv.2024.213881
  36. Ehrhorn, E.; Lovell, P.; Svechkarev, D.; Romanova, S.; Mohs, A. Optimizing the performance of silica nanoparticles functionalized with a near-infrared fluorescent dye for bioimaging applications. Nanotechnology, 2024, 35(30), 305605. doi: 10.1088/1361-6528/ad3fc5
  37. Gleixner, J.; Kopanchuk, S.; Grätz, L.; Tahk, M.-J.; Laasfeld, T.; Veikšina, S.; Höring, C.; Gattor, A. O.; Humphrys, L. J.; Müller, C.; Archipowa, N.; Köckenberger, J.; Heinrich, M. R.; Kutta, R. J.; Rinken, A.; Keller, M. Illuminating Neuropeptide Y Y4 Receptor Binding: Fluorescent Cyclic Peptides with Subnanomolar Binding Affinity as Novel Molecular Tools. ACS Pharmacol. Transl. Sci., 2024, 7(4), 1142–1168. doi: 10.1021/acsptsci.4c00013
  38. Cai, J.; Liu, S.; Zhong, Q.; Shang, Y.; Chen, Z.; Yao, Y.; Zhou, B.; Yin, F.; Zhao, J.; Zheng, L. Multifunctional PDA/ZIF8 based hydrogel dressing modulates the microenvironment to accelerate chronic wound healing by ROS scavenging and macrophage polarization. Chemical Engineering Journal, 2024, 487, 150632. doi: 10.1016/j.cej.2024.150632
  39. Yun, W.S.; Yang, W.; Shim, M.K.; Song, S.; Choi, J.; Kim, J.; Kim, J.; Moon, Y.; Jo, S.H.; Lim, D.-K.; Kim, K. Accurately controlled tumor temperature with silica-coated gold nanorods for optimal immune checkpoint blockade therapy. Biomaterials Research, 2024, 28, 0024. doi: 10.34133/bmr.0024
  40. Feld, L. G.; Boehme, S. C.; Morad, V.; Sahin, Y.; Kaul, C. J.; Dirin, D. N.; Rainò, G.; Kovalenko, M. V. Quantifying Förster Resonance Energy Transfer from Single Perovskite Quantum Dots to Organic Dyes. ACS Nano, 2024, 18(14), 9997–10007. doi: 10.1021/acsnano.3c11359
  41. Slapak, E.J.; el Mandili, M.; Ten Brink, M.S.; Kros, A.; Bijlsma, M.F.; Spek, C.A. CAPN2-responsive mesoporous silica nanoparticles: A promising nanocarrier for targeted therapy of pancreatic cancer. Cancer Letters, 2024, 590, 216845. doi: 10.1016/j.canlet.2024.216845
  42. Marziali, L.N.; Hwang, Y.; Palmisano, M.; Cuenda, A.; Sim, F.J.; Gonzalez, A.; Volsko, C.; Dutta, R.; Trapp, B.D.; Wrabetz, L.; Feltri, M.L. p38γ MAPK delays myelination and remyelination and is abundant in multiple sclerosis lesions. Brain, 2024, 147(5), 1871-1886. doi: 10.1093/brain/awad421
  43. Lysakova, E.; Shumeev, A.; Laktyushkin, V.; Chuvpilo, S.; Rybtsov, S. Assay Development for Phagocytosis Activity Evaluation. Biol. Life Sci. Forum, 2024, 31(1), 15. doi: 10.3390/ecm2023-16444
  44. Feng, X.; Cui, X.; Zhang, L.-S.; Ye, C.; Wang, P.; Zhong, Y.; Wu, T.; Zheng, Z.; He, C. Sequencing of N6-Methyl-Deoxyadenosine at Single-Base Resolution across the Mammalian Genome. Molecular Cell, 2024, 84(3), 596-610.e6. doi: 10.1016/j.molcel.2023.12.021
  45. Elkhashab, M.; Dilek, Y.; Foss, M.; Creemers, L. B.; Howard, K. A. A Modular Albumin-Oligonucleotide Biomolecular Assembly for Delivery of Antisense Therapeutics. Mol. Pharmaceutics, 2024, 21(2), 491–500. doi: 10.1021/acs.molpharmaceut.3c00561
  46. Chau, Q.; Corado-Santiago, L.; Jones, S.; Dattelbaum, J.; Skromne, I. Physicochemical and Inflammatory Analysis of Unconjugated and Conjugated Bone-Binding Carbon Dots. ACS Omega, 2024, 9(1), 1320-1326. doi: 10.1021/acsomega.3c07653
  47. Chernikov, I. V.; Ponomareva, U. A.; Meschaninova, M. I.; Bachkova, I. K.; Vlassov, V. V.; Zenkova, M. A.; Chernolovskaya, E. L. Cholesterol Conjugates of Small Interfering RNA: Linkers and Patterns of Modification. Molecules, 2024, 29(4), 786. doi: 10.3390/molecules29040786
  48. Baleva, M.V.; Piunova, U.; Chicherin, I.; Vasilev, R.; Levitskii, S.; Kamenski, P. Mitochondrial Protein SLIRP Affects Biosynthesis of Cytochrome c Oxidase Subunits in HEK293T Cells. International Journal of Molecular Sciences, 2024, 25(1), 93. doi: 10.3390/ijms25010093
  49. Shishkova, D.; Lobov, A.; Repkin, E.; Markova, V.; Markova, Y.; Sinitskaya, A.; Sinitsky, M.; Kondratiev, E.; Torgunakova, E.; Kutikhin, A. Calciprotein Particles Induce Cellular Compartment-Specific Proteome Alterations in Human Arterial Endothelial Cells. Journal of Cardiovascular Development and Disease, 2024, 11(1), 5. doi: 10.3390/jcdd11010005
  50. Han, G.; Kim, H.; Jang, H.; Kim, E.S.; Kim, S.H.; Yang, Y. Oral TNF-α siRNA delivery via milk-derived exosomes for effective treatment of inflammatory bowel disease. Bioactive Materials, 2024, 34, 138-149. doi: 10.1016/j.bioactmat.2023.12.010
  51. Chen, K.; Gu, L.; Zhang, Q.; Luo, Q.; Guo, S.; Wang, B.; Gong, Q.; Luo, K. Injectable alginate hydrogel promotes antitumor immunity through glucose oxidase and Fe3+ amplified RSL3-induced ferroptosis. Carbohydrate Polymers, 2024, 326, 121643. doi: 10.1016/j.carbpol.2023.121643
  52. Shik, A. V.; Sobolev, P. V.; Zubritskaya, Y. V.; Baytler, M. O.; Stepanova, I. A.; Chernyaev, A. P.; Borschegovskaya, P. Yu.; Zolotov, S. A.; Doroshenko, I. A.; Podrugina, T. A.; Bliznyuk, U. A.; Rodin, I. A.; Beklemishev, M. K. Rapid Testing of Irradiation Dose in Beef and Potatoes by Reaction-Based Optical Sensing Technique. Journal of Food Composition and Analysis, 2024, 127, 105946. doi: 10.1016/j.jfca.2023.105946
  53. Bondarev, N.A.; Bagaeva, D.F.; Bazhenov, S.V.; Buben, M.M.; Bulushova, N.V.; Ryzhykau, Y..L.; Okhrimenko, I.S.; Zagryadskaya, Y..A.; Maslov, I.V.; Anisimova, N.Y..; Sokolova, D.V.; Kuklin, A.I.; Pokrovsky, V.S.; Manukhov, I.V. Methionine gamma lyase fused with S3 domain VGF forms octamers and adheres to tumor cells via binding to EGFR. Biochemical and Biophysical Research Communications, 2024, 691, 149319. doi: 10.1016/j.bbrc.2023.149319
  54. Wu, S.-Y.; Lai, H.-T.; Sanjib Banerjee, N.; Ma, Z.; Santana, J.F.; Wei, S.; Liu, X.; Zhang, M.; Zhan, J.; Chen, H.; Posner, B.; Chen, Y.; Price, D.H.; Chow, L.T.; Zhou, J.; Chiang, C.-M. IDR-targeting compounds suppress HPV genome replication via disruption of phospho-BRD4 association with DNA damage response factors. Molecular Cell, 2024, 84(2), 202-220.e15. doi: 10.1016/j.molcel.2023.11.022
  55. Chen, Z.; Zakrzewska, S.; Hajare, H.S.; Du Bois, J.; Minor, D.L. Expression, purification, and characterization of anuran saxiphilins using thermofluor, fluorescence polarization, and isothermal titration calorimetry. STAR Protocols, 2024, 5(1), 102792. doi: 10.1016/j.xpro.2023.102792
  56. Li, Y.; Yang, J.; Chen, X.; Hu, H.; Lan, N.; Zhao, J.; Zheng, L. Mitochondrial-targeting and NIR-responsive Mn3O4@PDA@Pd-SS31 nanozymes reduce oxidative stress and reverse mitochondrial dysfunction to alleviate osteoarthritis. Biomaterials, 2024, 305, 122449. doi: 10.1016/j.biomaterials.2023.122449
  57. Liang, J.; Han, J.; Gao, X.; Jia, H.; Li, R.; Tse, E. C. M.; Li, Y. Clickable APEX2 Probes for Enhanced RNA Proximity Labeling in Live Cells. Anal. Chem., 2024, 96(2), 685–693. doi: 10.1021/acs.analchem.3c03614
  58. Liu, Y.; Ouyang, Y.; Yu, L.; Wang, P.; Peng, Z.; Liu, H.; Zhao, S.; Wang, H.; Zhou, Z.; Deng, Y.; Liu, Y.; Xie, J. Novel approach for enhancing skin allograft survival by bioadhesive nanoparticles loaded with rapamycin. International journal of pharmaceutics, 2024, 651, 123742. doi: 10.1016/j.ijpharm.2023.123742
  59. Zhang, Y.; Wang, H.; Zheng, Y.; Wu, Z.; Liu, J.; Cheng, F.; Wang, K. Degradation of Angelica sinensis polysaccharide: Structures and protective activities against ethanol-induced acute liver injury. Carbohydrate polymers, 2024, 328, 121745. doi: 10.1016/j.carbpol.2023.121745
  60. Smirnov, A.N.; Shevchuk, A.I.; Volkova, A.V.; Kalganov, V.D.; Solovyeva, E.V. Gold-silica plasmonic nanobones with tunable size and optical bimodality for bioimaging. Colloids and surfaces. A, Physicochemical and engineering aspects, 2024, 684, 133115. doi: 10.1016/j.colsurfa.2023.133115
  61. Liu, M.-C.J.; Yeh, F.-L.J.; Yvon, R.; Simpson, K.; Jordan, S.; Chambers, J.; Wu, H.-M.; Cheung, A.Y. Extracellular pectin-RALF phase separation mediates FERONIA global signaling function. Cell, 2024, 187(2), 312-330.e22. doi: 10.1016/j.cell.2023.11.038
  62. Wen, H.; Martínez, M.G.; Happonen, E.; Qian, J.; Vallejo, V.G.; Mendazona, H.J.; Jokivarsi, K.; Scaravilli, M.; Latonen, L.; Llop, J.; Lehto, V.-P.; Xu, W. A PEG-assisted membrane coating to prepare biomimetic mesoporous silicon for PET/CT imaging of triple-negative breast cancer. International journal of pharmaceutics, 2024, 652, 123764. doi: 10.1016/j.ijpharm.2023.123764
  63. Kopp, A.; Kwon, H.; Johnston, C.; Vance, S.; Legg, J.; Galson-Holt, L.; Thurber, G.M. Impact of tissue penetration and albumin binding on design of T cell targeted bispecific agents. Neoplasia, 2024, 48, 100962. doi: 10.1016/j.neo.2023.100962
  64. Pytlíková, S.; Pechar, M.; Chytil, P.; Studenovský, M.; Pola, R.; Kotrchová, L.; Konefał, R.; Čtveráčková, L.; Laga, R.; Pankrác, J.; Gao, S.; Jiang, B.; Yang, K.; Fang, J.; Filipová, M.; Etrych, T. Highly hydrophilic methacrylamide-based copolymers as precursors for polymeric nanomedicines containing anthracyclines. European Polymer Journal, 2024, 205, 112756. doi: 10.1016/j.eurpolymj.2024.112756
  65. Huber, R.; Lee, J.; Borretta, L.; Tessier-Cloutier, B.; Lum, A.; Yip, S.; Horst, B.A. TERT promoter mutations in atypical melanocytic lesions: A series of seven cases with adverse melanoma-specific outcome. Human pathology, 2024, 144, 34-39. doi: 10.1016/j.humpath.2024.01.003
  66. Xu, M.J.; Jordan, P.W. SMC5/6 Promotes Replication Fork Stability via Negative Regulation of the COP9 Signalosome. International Journal of Molecular Sciences, 2024, 25(2), 952. doi: 10.3390/ijms25020952
  67. Yang, B.; Picchetti, P.; Wang, Y.; Wang, W.; Seeger, C.; Bozov, K.; Malik, S.; Mallach, D.; Schäfer, A.H.; Ibrahim, M.; Hirtz, M.; Powell, A.K. Patterned immobilization of polyoxometalate-loaded mesoporous silica particles via amine-ene Michael additions on alkene functionalized surfaces. Scientific Reports, 2024, 14, 1249. doi: 10.1038/s41598-023-50846-2
  68. Osuofa, J.; Husson, S.M. Preparation of Protein A Membranes Using Propargyl Methacrylate-Based Copolymers and Copper-Catalyzed Alkyne–Azide Click Chemistry. Polymers, 2024, 16(2), 239. doi: 10.3390/polym16020239
  69. Martin-Alonso, C.; Tabrizi, S.; Xiong, K.; Blewett, T.; Sridhar, S.; Crnjac, A.; Patel, S.; An, Z.; Bekdemir, A.; Shea, D.; Wang, S.-T.; Rodriguez-Aponte, S.; Naranjo, C.A.; Rhoades, J.; Kirkpatrick, J.D.; Fleming, H.E.; Amini, A.P.; Golub, T.R.; Love, J.C.; Bhatia, S.N.; Adalsteinsson, V.A. Priming agents transiently reduce the clearance of cell-free DNA to improve liquid biopsies. Science, 2024, 383(6680), eadf2341. doi: 10.1126/science.adf2341
  70. Geng, T.; Paek, S.Y.; Leung, E.; Chamley, L.W.; Wu, Z. Comparing extracellular vesicles from four different cell origins for intracellular drug delivery to pancreatic cancer cells: Small or large vesicles?. Journal of drug delivery science and technology, 2024, 93, 105416. doi: 10.1016/j.jddst.2024.105416
  71. Kaluzhskiy, L.; Yablokov, E.; Gnedenko, O.; Burkatovskii, D.; Maslov, I.; Bogorodskiy, A.; Ershov, P.; Tsybruk, T.; Zelepuga, E.; Rutckova, T.; Kozlovskaya, E.; Dmitrenok, P.; Gilep, A.; Borshchevskiy, V.; Strushkevich, N.; Ivanov, A. The effect of membrane composition on the interaction between human CYP51 and its flavonoid inhibitor - luteolin 7,3′-disulfate. Biochimica et biophysica acta. Biomembranes, 2024, 1866(3), 184286. doi: 10.1016/j.bbamem.2024.184286
  72. Omole, A. O.; Affonso de Oliveira, J. F.; Sutorus, L.; Steinmetz, N. F. Pharmacology of a Plant Virus Immunotherapy Candidate for Peritoneal Metastatic Ovarian Cancer. ACS Pharmacol. Transl. Sci., 2024, 7(2), 445–455. doi: 10.1021/acsptsci.3c00285
  73. Morrow, J. P.; Mazrad, Z. A. I.; Warne, N. M.; Ayton, S.; Bush, A. I.; Kempe, K. Schiff-Base Cross-Linked Poly(2-Oxazoline) Micelle Drug Conjugates Possess Antiferroptosis Activity in Numerous In Vitro Cell Models. Biomacromolecules, 2024, 25(2), 1068–1083. doi: 10.1021/acs.biomac.3c01106
  74. Fei, C.; Liu, L.; Qi, H.; Peng, Y.; Han, J.; Wang, C.; Li, X. Curdlan-Decorated Fullerenes Mitigate Immune-Mediated Hepatic Injury for Autoimmune Hepatitis Therapeutics via Reducing Macrophage Infiltration. ACS Appl. Mater. Interfaces, 2024, 16(5), 5536–5547. doi: 10.1021/acsami.3c16168
  75. Kwon, S.; Meng, F.; Tamam, H.; Gadalla, H. H.; Wang, J.; Dong, B.; Hopf Jannasch, A. S.; Ratliff, T. L.; Yeo, Y. Systemic Delivery of Paclitaxel by Find-Me Nanoparticles Activates Antitumor Immunity and Eliminates Tumors. ACS Nano, 2024, 18(4), 3681–3698. doi: 10.1021/acsnano.3c11445
  76. Trac, N.; Chen, Z.; Oh, H.; Jones, L.; Huang, Y.; Giblin, J.; Gross, M.; Sta Maria, N. S.; Jacobs, R. E.; Chung, E. J. MRI Detection of Lymph Node Metastasis through Molecular Targeting of C–C Chemokine Receptor Type 2 and Monocyte Hitchhiking. ACS Nano, 2024, 18(3), 2091–2104. doi: 10.1021/acsnano.3c09201
  77. Fortea, E.; Lee, S.; Chadda, R.; Robertson, J.L.; Boudker, O.; Accardi, A. Structural basis of pH-dependent activation in a CLC transporter. Biophysical Journal, 2024, 123(3), 175a. doi: 10.1016/j.bpj.2023.11.1155
  78. Yahya, S.; Sulaiman, M.K.; Sudhandiran, G. Caffeic acid phenethyl ester mediates apoptosis in serum‐starved HT29 colon cancer cells through modulation of heat shock proteins and MAPK pathways. Cell biochemistry and function, 2024, 42(2), e3942. doi: 10.1002/cbf.3942
  79. Jaiswal, S.; Wang, F.; Wu, X.; Chang, T.-S.; Shirazi, A.; Lee, M.; Dame, M.K.; Spence, J.R.; Wang, T.D. Near-Infrared In Vivo Imaging of Claudin-1 Expression by Orthotopically Implanted Patient-Derived Colonic Adenoma Organoids. Diagnostics, 2024, 14(3), 273. doi: 10.3390/diagnostics14030273
  80. Wu, F.; Ren, Y.; Lv, W.; Liu, X.; Wang, X.; Wang, C.; Cao, Z.; Liu, J.; Wei, J.; Pang, Y. Generating dual structurally and functionally skin-mimicking hydrogels by crosslinking cell-membrane compartments. Nature Communications, 2024, 15(1), 802. doi: 10.1038/s41467-024-45006-7
  81. Talebloo, N.; Bernal, M.A.O.; Kenyon, E.; Mallett, C.L.; Mondal, S.K.; Fazleabas, A.; Moore, A. Imaging of Endometriotic Lesions Using cRGD-MN Probe in a Mouse Model of Endometriosis. Nanomaterials, 2024, 14(3), 319. doi: 10.3390/nano14030319
  82. Goto, Y.; Ando, K.; Takakura, H.; Nakajima, K.; Kobayashi, M.; Inanami, O.; Taketsugu, T.; Ogawa, M. Development of a red-shifted photosensitizer for near-infrared photoimmunotherapy of cancer. Journal of Photochemistry and Photobiology, 2024, 20, 100230. doi: 10.1016/j.jpap.2024.100230
  83. Chang, C.; Liu, H.; Li, X.; Song, D.; Liu, Y.; Lu, C.; Zhen, Y.; Chen, Y.; Xu, J.; Li, W.; Jia, X.; Chen, Z.; Chen, R. Combined ROS Responsive Polydopamine-Coated Berberine Nanoparticles Effective Against Ulcerative Colitis in Mouse Model. International Journal of Nanomedicine, 2024, 19, 1205-1224. doi: 10.2147/ijn.s442761
  84. Sousa de Almeida, M.; Lee, A.; Itel, F.; Maniura-Weber, K.; Petri-Fink, A.; Rothen-Rutishauser, B. The Effect of Substrate Properties on Cellular Behavior and Nanoparticle Uptake in Human Fibroblasts and Epithelial Cells. Nanomaterials, 2024, 14(4), 342. doi: 10.3390/nano14040342
  85. Deng, L.; Olea, A.R.; Ortiz‐Perez, A.; Sun, B.; Wang, J.; Pujals, S.; Palmans, A.R.A.; Albertazzi, L. Imaging Diffusion and Stability of Single‐Chain Polymeric Nanoparticles in a Multi‐Gel Tumor‐on‐a‐Chip Microfluidic Device. Small methods, 2024, 2301072. doi: 10.1002/smtd.202301072
  86. Dudkina, E.V.; Vasilieva, E.A.; Ulyanova, V.V.; Zakharova, L.Y..; Ilinskaya, O.N. Surfactants as a Means of Delivering a Reporter Genetic Construct Based on Binase Suicide Gene to Tumor Cells. Russian Journal of Bioorganic Chemistry, 2024, 50, 45-55. doi: 10.1134/s1068162024010072
  87. Minutti, C.M.; Piot, C.; Pereira da Costa, M.; Chakravarty, P.; Rogers, N.; Huerga Encabo, H.; Cardoso, A.; Loong, J.; Bessou, G.; Mionnet, C.; Langhorne, J.; Bonnet, D.; Dalod, M.; Tomasello, E.; Reis e Sousa, C. Distinct ontogenetic lineages dictate cDC2 heterogeneity. Nature Immunology, 2024, 25, 448–461. doi: 10.1038/s41590-024-01745-9
  88. Huang, S.; Gao, Y.; Ma, L.; Jia, B.; Zhao, W.; Yao, Y.; Li, W.; Lin, T.; Wang, R.; Song, J.; Zhang, W. Design of pH-responsive antimicrobial peptide melittin analog-camptothecin conjugates for tumor therapy. Asian Journal of Pharmaceutical Sciences, 2024, 19(1), 100890. doi: 10.1016/j.ajps.2024.100890
  89. Garafutdinov, R.R.; Kupova, O.Y..; Sakhabutdinova, A.R. Influence of Nucleotide Context on Non-Specific Amplification of DNA with Bst exo– DNA Polymerase. Biochemistry Moscow, 2024, 89(1), 53-64. doi: 10.1134/s0006297924010036
  90. Katkova, S.A.; Bunev, A.S.; Gasanov, R.E.; Khochenkov, D.A.; Kulsha, A.V.; Ivashkevich, O.A.; Serebryanskaya, T.V.; Kinzhalov, M. Metal‐(Acyclic Diaminocarbene) Complexes Demonstrate Nanomolar Antiproliferative Activity against Triple‐Negative Breast Cancer. Chem. Eur. J., 2024, e202400101. doi: 10.1002/chem.202400101
  91. Qiu, B.; Zandkarimi, F.; Bezjian, C.T.; Reznik, E.; Soni, R.K.; Gu, W.; Jiang, X.; Stockwell, B.R. Phospholipids with two polyunsaturated fatty acyl tails promote ferroptosis. Cell, 2024, 187(5), 1177-1190.E18. doi: 10.1016/j.cell.2024.01.030
  92. Teng Zhang; Guodong Wang. Inhibition of RXRA-mediated PLA2G2A improves delirium in COPD mice by regulating endoplasmic reticulum stress pathway and inhibiting cell apoptosis. Cellular and Molecular Biology, 2024, 70(1), 226-232. doi: 10.14715/cmb/2024.70.1.31
  93. Kiseleva, D.; Kolmogorov, V.; Cherednichenko, V.; Khovantseva, U.; Bogatyreva, A.; Markina, Y.; Gorelkin, P.; Erofeev, A.; Markin, A. Effect of LDL Extracted from Human Plasma on Membrane Stiffness in Living Endothelial Cells and Macrophages via Scanning Ion Conductance Microscopy. Cells, 2024, 13(4), 358. doi: 10.3390/cells13040358
  94. Seo, H.S.; Han, J.-H.; Lim, J.; Bae, G.-H.; Byun, M.J.; Wang, C.-P.J.; Han, J.; Park, J.; Park, H.H.; Shin, M.; Park, T.-E.; Kim, T.-H.; Kim, S.-N.; Park, W.; Park, C.G. Enhanced Post-Surgical Cancer Treatment Using Methacrylated Glycol Chitosan Hydrogel for Sustained DNA/Doxorubicin Delivery and Immunotherapy. Biomaterials Research, 2024, 28, 0008. doi: 10.34133/bmr.0008
  95. Tereshchenkov, A. G.; Khairullina, Z. Z.; Volynkina, I. A.; Lukianov, D. A.; Nazarov, P. A.; Pavlova, J. A.; Tashlitsky, V. N.; Razumova, E. A.; Ipatova, D. A.; Timchenko, Y. V.; Senko, D. A.; Efremenkova, O. V.; Paleskava, A.; Konevega, A. L.; Osterman, I. A.; Rodin, I. A.; Sergiev, P. V.; Dontsova, O. A.; Bogdanov, A. A.; Sumbatyan, N. V. Triphenylphosphonium Analogs of Short Peptide Related to Bactenecin 7 and Oncocin 112 as Antimicrobial Agents. Pharmaceutics, 2024, 16(1), 148. doi: 10.3390/pharmaceutics16010148
  96. Zharkov, T. D.; Markov, O. V.; Zhukov, S. A.; Khodyreva, S. N.; Kupryushkin, M. S. Influence of Combinations of Lipophilic and Phosphate Backbone Modifications on Cellular Uptake of Modified Oligonucleotides. Molecules, 2024, 29(2), 452. doi: 10.3390/molecules29020452
  97. Waduthanthri, K. D.; Kuppan, P.; Korbutt, G. S.; Pepper, A. R.; Unsworth, L. D. Molecular Retention Limitations for Prevascularized Subcutaneous Sites for Islet Transplantation. Biomacromolecules, 2024, 25(3), 1439–1447. doi: 10.1021/acs.biomac.3c00977
  98. Narum, S.; Deal, B.; Ogasawara, H.; Mancuso, J. N.; Zhang, J.; Salaita, K. An Endosomal Escape Trojan Horse Platform to Improve Cytosolic Delivery of Nucleic Acids. ACS Nano, 2024, 18(8), 6186–6201. doi: 10.1021/acsnano.3c09027
  99. Zhang, J.; Cui, B.; He, T.; Hei, R.; Yang, L.; Liu, C.; Wu, X.; Wang, X.; Gao, Z.; Lin, F.; Zhang, H.; Dong, K. Enhancing Neuroprotection in Mouse Model of Parkinson’s Disease through Protein Nanosystem Conjugation with ApoE Peptide for MiR-124 Delivery. ACS Appl. Mater. Interfaces, 2024, 16(7), 8199–8212. doi: 10.1021/acsami.3c13849
  100. Stinson, B.M.; Carney, S.M.; Walter, J.C.; Loparo, J.J. Structural role for DNA Ligase IV in promoting the fidelity of non-homologous end joining. Nature Communications, 2024, 15, 1250. doi: 10.1038/s41467-024-45553-z
  101. Moochickal Assainar, B.; Ragunathan, K.; Baldridge, R.D. Direct observation of autoubiquitination for an integral membrane ubiquitin ligase in ERAD. Nature Communications, 2024, 15, 1340. doi: 10.1038/s41467-024-45541-3
  102. Goedhart, J. Studentsourcing—Aggregating and reusing data from a practical cell biology course. PLOS Computational Biology, 2024, 20(2), e1011836. doi: 10.1371/journal.pcbi.1011836
  103. Dymova, M.A.; Malysheva, D.O.; Popova, V.K.; Dmitrienko, E.V.; Endutkin, A.V.; Drokov, D.V.; Mukhanov, V.S.; Byvakina, A.A.; Kochneva, G.V.; Artyushenko, P.V.; Shchugoreva, I.A.; Rogova, A.V.; Tomilin, F.N.; Kichkailo, A.S.; Richter, V.A.; Kuligina, E.V. Characterizing Aptamer Interaction with the Oncolytic Virus VV-GMCSF-Lact. Molecules, 2024, 29(4), 848. doi: 10.3390/molecules29040848
  104. Yen, T.-Y.C.; Abbasi, A.Z.; He, C.; Lip, H.-Y.; Park, E.; Amini, M.A.; Adissu, H.A.; Foltz, W.; Rauth, A.M.; Henderson, J.; Wu, X.Y. Biocompatible and bioactivable terpolymer-lipid-MnO2 Nanoparticle-based MRI contrast agent for improving tumor detection and delineation. Materials Today Bio, 2024, 25, 100954. doi: 10.1016/j.mtbio.2024.100954
  105. Ehrman, R.N.; Brohlin, O.R.; Wijesundara, Y.H.; Kumari, S.; Trashi, O.; Howlett, T.S.; Trashi, I.; Herbert, F.C.; Raja, A.; Koirala, S.; Tran, N.; Al-Kharji, N.M.; Tang, W.; Senarathna, M.C.; Hagge, L.M.; Smaldone, R.A.; Gassensmith, J.J. A scalable synthesis of adjuvanting antigen depots based on metal–organic frameworks. Chemical Science, 2024, 15(8), 2731-2744. doi: 10.1039/d3sc06734c
  106. Yamaguchi, A. Evaluation of fish pituitary spheroids to study annual endocrine reproductive control. General and comparative endocrinology, 2024, 351, 114481. doi: 10.1016/j.ygcen.2024.114481
  107. Khan, S.; Molloy, J.E.; Puhl, H.; Schulman, H.; Vogel, S.S. Real-time single-molecule imaging of CaMKII-calmodulin interactions. Biophysical Journal, 2024, 123(7), 824-838. doi: 10.1016/j.bpj.2024.02.021
  108. Dopeso, H.; Rodrigues, P.; Cartón-García, F.; Macaya, I.; Bilic, J.; Anguita, E.; Jing, L.; Brotons, B.; Vivancos, N.; Beà, L.; Sánchez-Martín, M.; Landolfi, S.; Hernandez-Losa, J.; Ramon y Cajal, S.; Nieto, R.; Vicario, M.; Farre, R.; Schwartz Jr, S.; van Ijzendoorn, S.C.D.; Kobayashi, K.; Martinez-Barriocanal, Á.; Arango, D. RhoA downregulation in the murine intestinal epithelium results in chronic Wnt activation and increased tumorigenesis. iScience, 2024, 27(4), 109400. doi: 10.1016/j.isci.2024.109400
  109. Blechar, J.; de Jesus, V.; Fürtig, B.; Hengesbach, M.; Schwalbe, H. Shine–Dalgarno Accessibility Governs Ribosome Binding to the Adenine Riboswitch. ACS Chem. Biol., 2024, 19(3), 607–618. doi: 10.1021/acschembio.3c00435
  110. Liu, Z.; Hao, X.; Qian, J.; Zhang, H.; Bao, H.; Yang, Q.; Gu, W.; Huang, X.; Zhang, Y. Enzyme/PH Dual-Responsive Engineered Nanoparticles for Improved Tumor Immuno-Chemotherapy. ACS Appl. Mater. Interfaces, 2024, 16(10), 12951–12964. doi: 10.1021/acsami.3c18348
  111. Hsia, O.; Hinterndorfer, M.; Cowan, A. D.; Iso, K.; Ishida, T.; Sundaramoorthy, R.; Nakasone, M. A.; Imrichova, H.; Schätz, C.; Rukavina, A.; Husnjak, K.; Wegner, M.; Correa-Sáez, A.; Craigon, C.; Casement, R.; Maniaci, C.; Testa, A.; Kaulich, M.; Dikic, I.; Winter, G. E.; Ciulli, A. Targeted Protein Degradation via Intramolecular Bivalent Glues. Nature, 2024, 627(8002), 204–211. doi: 10.1038/s41586-024-07089-6
  112. Montepietra, D.; Tesei, G.; Martins, J.M.; Kunze, M.B.A.; Best, R.B.; Lindorff-Larsen, K. FRETpredict: a Python package for FRET efficiency predictions using rotamer libraries. Communications Biology, 2024, 7, 298. doi: 10.1038/s42003-024-05910-6
  113. Xu, W.; He, M.; Lu, Q. Fibronectin Connecting Cell Sheet Based on Click Chemistry for Wound Repair. Advanced Science, 2024, 11(11), 2306746. doi: 10.1002/advs.202306746
  114. González-Gamboa, I.; Caparco, A.A.; McCaskill, J.; Fuenlabrada-Velázquez, P.; Hays, S.S.; Jin, Z.; Jokerst, J.V.; Pokorski, J.K.; Steinmetz, N.F. Inter-coat protein loading of active ingredients into Tobacco mild green mosaic virus through partial dissociation and reassembly of the virion. Scientific Reports, 2024, 14, 7168. doi: 10.1038/s41598-024-57200-0
  115. Li, Z.; Kovshova, T.; Malinovskaya, J.; Knoll, J.; Shanehsazzadeh, S.; Osipova, N.; Chernysheva, A.; Melnikov, P.; Gelperina, S.; Wacker, M.G. Blood-Nanoparticle Interactions Create a Brain Delivery Superhighway for Doxorubicin. International Journal of Nanomedicine, 2024, 19, 2039-2056. doi: 10.2147/IJN.S440598
  116. Kirsanov, R.S.; Khailova, L.S.; Rokitskaya, T.I.; Lyamzaev, K.G.; Panteleeva, A.A.; Nazarov, P.A.; Firsov, A.M.; Iaubasarova, I.R.; Korshunova, G.A.; Kotova, E.A.; Antonenko, Y.N. Synthesis of Triphenylphosphonium-Linked Derivative of 3,5-Di tert -butyl-4-hydroxybenzylidene-malononitrile (SF6847) via Knoevenagel Reaction Yields an Effective Mitochondria-Targeted Protonophoric Uncoupler. ACS Omega, 2024, 9(10), 11551-11561. doi: 10.1021/acsomega.3c08621
  117. Nabar, N.; Dacoba, T.G.; Covarrubias, G.; Romero-Cruz, D.; Hammond, P.T. Electrostatic adsorption of polyanions onto lipid nanoparticles controls uptake, trafficking, and transfection of RNA and DNA therapies. Proceedings of the National Academy of Sciences of the United States of America, 2024, 121(11), e2307809121. doi: 10.1073/pnas.2307809121
  118. Skardžiūtė, K.; Kvederavičiūtė, K.; Pečiulienė, I.; Narmontė, M.; Gibas, P.; Ličytė, J.; Klimašauskas, S.; Kriukienė, E. One-pot trimodal mapping of unmethylated, hydroxymethylated, and open chromatin sites unveils distinctive 5hmC roles at dynamic chromatin loci. Cell Chemical Biology, 2024, 31(3), 607-621.e9. doi: 10.1016/j.chembiol.2023.12.003
  119. Feng, Q.; Bennett, Z.; Grichuk, A.; Pantoja, R.; Huang, T.; Faubert, B.; Huang, G.; Chen, M.; DeBerardinis, R.J.; Sumer, B.D.; Gao, J. Severely polarized extracellular acidity around tumour cells. Nature Biomedical Engineering, 2024. doi: 10.1038/s41551-024-01178-7
  120. Albaladejo-García, V.; Morán, L.; Santos-Coquillat, A.; González, M.I.; Ye, H.; Vázquez Ogando, E.; Vaquero, J.; Cubero, F.J.; Desco, M.; Salinas, B. Curcumin encapsulated in milk small extracellular vesicles as a nanotherapeutic alternative in experimental chronic liver disease. Biomedicine & Pharmacotherapy, 2024, 173, 116381. doi: 10.1016/j.biopha.2024.116381
  121. Vozgirdaite, D.; Hervé-Aubert, K.; Uzbekov, R.; Chourpa, I.; Allard-Vannier, E. Design, optimization, characterization, and in vitro evaluation of metformin-loaded liposomes for triple negative breast cancer treatment. Journal of Liposome Research, 2024, 1-15. doi: 10.1080/08982104.2024.2321528
  122. Xu, Y.; Lv, J.; Liu, F.; Wang, J.; Liu, Y.; Kong, C.; Li, Y.; Shen, N.; Gu, Z.; Tang, Z.; Chen, X. Tumor Microenvironment Remodeling‐Mediated Sequential Drug Delivery Potentiates Treatment Efficacy. Advanced Materials, 2024. doi: 10.1002/adma.202312493
  123. Lu, B.; Sun, Y.-; Chen, B.-; Yang, B.; He, Q.-; Li, J.; Cao, J. zDHHC20-driven S-palmitoylation of CD80 is required for its costimulatory function. Acta Pharmacologica Sinica, 2024. doi: 10.1038/s41401-024-01248-1
  124. Zubareva, V.D.; Bytov, M.V.; Zaitseva, O.S.; Sokolova, O.V. Development of Real-Time PCR Kits for Bovine Haplotypes HH3, HH6, HH7 Diagnosis. Russian Journal of Genetics, 2024, 60(2), 254-258. doi: 10.1134/s1022795424020145
  125. Rinaldi, A.; Dumas, F.; Duskey, J.T.; Imbriano, C.; Belluti, S.; Roy, C.; Ottonelli, I.; Vandelli, M.A.; Ruozi, B.; Garcion, E.; Tosi, G.; Boury, F. Polymer-lipid hybrid nanomedicines to deliver siRNA in and against glioblastoma cells. International Journal of Pharmaceutics, 2024, 654, 123994. doi: 10.1016/j.ijpharm.2024.123994
  126. Shevchuk, A.I.; Smirnov, A.N.; Svinko, V.O.; Solovyeva, E.V. Surface-Enhanced Raman Scattering of Sulfo-Cyanine NHS Esters Adsorbed on Gold Nanoparticles. Russian Journal of General Chemistry, 2024, 94, S20-S27. doi: 10.1134/s1070363224140032
  127. Dukat, A.M.; Kuznetsova, A.M.; Klyagin, S.D.; Trushin, V.O.; Klyukina, A.A.; El’cheninov, A.G.; Danilova, I.V. Chitin Degradation by Microbial Communities of the Kandalaksha Bay, White Sea. Microbiology, 2024, 93, 61-78. doi: 10.1134/s0026261723603111
  128. Fadeev, A.Y..; Gavirova, L.A.; Georgieva, M.L.; Kozlovsky, V.V.; Simakova, U.V.; Shestakov, A.I.; Bubnova, E.N. Effect of Hydrocarbon Pollution on the Fungal Communities of the Littoral Sediments of the White and Barents Seas. Microbiology, 2024, 93, 51-60. doi: 10.1134/s002626172360324x
  129. Chen, H.; Liu, D.; Guo, J.; Aditham, A.; Zhou, Y.; Tian, J.; Luo, S.; Ren, J.; Hsu, A.; Huang, J.; Kostas, F.; Wu, M.; Liu, D.R.; Wang, X. Branched chemically modified poly(A) tails enhance the translation capacity of mRNA. Nature Biotechnology, 2024. doi: 10.1038/s41587-024-02174-7
  130. Belyaev, I.B.; Zelepukin, I.V.; Kotelnikova, P.A.; Tikhonowski, G.V.; Popov, A.A.; Kapitannikova, A.Y..; Barman, J.; Kopylov, A.N.; Bratashov, D.N.; Prikhozhdenko, E.S.; Kabashin, A.V.; Deyev, S.M.; Zvyagin, A.V. Laser‐Synthesized Germanium Nanoparticles as Biodegradable Material for Near‐Infrared Photoacoustic Imaging and Cancer Phototherapy. Advanced Science, 2024, 2307060. doi: 10.1002/advs.202307060
  131. Hu, K.; Harman, A.; Baharlou, H. Imaging Mass Cytometry for In Situ Immune Profiling. Flow Cytometry Protocols, 2024, 2779, 407-423. doi: 10.1007/978-1-0716-3738-8_19
  132. Romashin, D.; Rusanov, A.; Tolstova, T.; Varshaver, A.; Netrusov, A.; Kozhin, P.; Luzgina, N. Loss of mutant p53 in HaCaT keratinocytes promotes cadmium-induced keratin 17 expression and cell death. Biochemical and Biophysical Research Communications, 2024, 709, 149834. doi: 10.1016/j.bbrc.2024.149834
  133. Vellani, V.; Cuccaro, A.; Oliva, M.; Pretti, C.; Renzi, M. Assessing combined effects of long-term exposure to copper and marine heatwaves on the reef-forming serpulid Ficopomatus enigmaticus through a biomarker approach. Marine Pollution Bulletin, 2024, 201, 116269. doi: 10.1016/j.marpolbul.2024.116269
  134. Kim, U.; Oh, S.-W. Characterizing the formation and cross-contamination potential of multi-species biofilms in poultry processing environments: S. Enteritidis, C. jejuni and C. perfringens. Food Control, 2024, 163, 110481. doi: 10.1016/j.foodcont.2024.110481
  135. Li, C.; Clauson, R.; Bugada, L. F.; Ke, F.; He, B.; Yu, Z.; Chen, H.; Jacobovitz, B.; Hu, H.; Chuikov, P.; Hill, B. D.; Rizvi, S. M.; Song, Y.; Sun, K.; Axenov, P.; Huynh, D.; Wang, X.; Garmire, L.; Lei, Y. L.; Grigorova, I.; Wen, F.; Cascalho, M.; Gao, W.; Sun, D. Antigen-Clustered Nanovaccine Achieves Long-Term Tumor Remission by Promoting B/CD 4 T Cell Crosstalk. ACS Nano, 2024, 18(13), 9584–9604. doi: 10.1021/acsnano.3c13038
  136. Li, Q.; Byun, J.; Choi, J.; Park, J.; Lee, J.; Oh, Y.-K. Nanomodulator-Mediated Restructuring of Adipose Tissue Immune Microenvironments for Antiobesity Treatment. ACS Nano, 2024, 18(13), 9311–9330. doi: 10.1021/acsnano.3c06001
  137. Kim, T.; Han, H. S.; Yang, K.; Kim, Y. M.; Nam, K.; Park, K. H.; Choi, S. Y.; Park, H. W.; Choi, K. Y.; Roh, Y. H. Nanoengineered Polymeric RNA Nanoparticles for Controlled Biodistribution and Efficient Targeted Cancer Therapy. ACS Nano, 2024, 18(11), 7972–7988. doi: 10.1021/acsnano.3c10732
  138. Nguyen, A.; Ramesh, A.; Fish, A.; Kulkarni, A.A. Dual‐Sensing Nanoreporter for Dynamic and High‐Throughput Monitoring of Immune Checkpoint Inhibitor Responses in Tumor‐Derived Organoids. Advanced functional materials, 2024. doi: 10.1002/adfm.202400393
  139. Hernández-Rollán, C.; Ehrmann, A.K.; Vlassis, A.; Kandasamy, V.; Nørholm, M.H.H. Neq2X7: a multi-purpose and open-source fusion DNA polymerase for advanced DNA engineering and diagnostics PCR. BMC Biotechnology, 2024, 24, 17. doi: 10.1186/s12896-024-00844-7
  140. Lim, S.; Ha, Y.; Lee, B.; Shin, J.; Rhim, T. Calnexin as a dual-role biomarker: antibody-based diagnosis and therapeutic targeting in lung cancer. BMB Reports, 2024, 57(3), 155-160. doi: 10.5483/BMBRep.2023-0228
  141. Alruwaili, M.M.; Zonneville, J.; Naranjo, M.N.; Serio, H.; Melendy, T.; Straubinger, R.M.; Gillard, B.; Foster, B.A.; Rajan, P.; Attwood, K.; Chatley, S.; Iyer, R.; Fountzilas, C.; Bakin, A.V. A synergistic two-drug therapy specifically targets a DNA repair dysregulation that occurs in p53-deficient colorectal and pancreatic cancers. Cell Reports Medicine, 2024, 5(3), 101434. doi: 10.1016/j.xcrm.2024.101434
  142. Ho H’ng, C.; Amarasinghe, S.L.; Zhang, B.; Chang, H.; Qu, X.; Powell, D.R.; Rosello-Diez, A. Compensatory growth and recovery of cartilage cytoarchitecture after transient cell death in fetal mouse limbs. Nature Communications, 2024, 15, 2940. doi: 10.1038/s41467-024-47311-7
  143. Sinitsky, M.; Repkin, E.; Sinitskaya, A.; Markova, V.; Shishkova, D.; Barbarash, O. Proteomic Profiling of Endothelial Cells Exposed to Mitomycin C: Key Proteins and Pathways Underlying Genotoxic Stress-Induced Endothelial Dysfunction. International Journal of Molecular Sciences, 2024, 25(7), 4044. doi: 10.3390/ijms25074044
  144. Bykonia, E.N.; Kleymenov, D.A.; Gushchin, V.A.; Siniavin, A.E.; Mazunina, E.P.; Kozlova, S.R.; Zolotar, A.N.; Usachev, E.V.; Kuznetsova, N.A.; Shidlovskaya, E.V.; Pochtovyi, A.A.; Kustova, D.D.; Ivanov, I.A.; Dmitriev, S.E.; Ivanov, R.A.; Logunov, D.Y.; Gintsburg, A.L. Major Role of S-Glycoprotein in Providing Immunogenicity and Protective Immunity in mRNA Lipid Nanoparticle Vaccines Based on SARS-CoV-2 Structural Proteins. Vaccines, 2024, 12(4), 379. doi: 10.3390/vaccines12040379
  145. Mazunina, E.P.; Gushchin, V.A.; Kleymenov, D.A.; Siniavin, A.E.; Burtseva, E.I.; Shmarov, M.M.; Mukasheva, E.A.; Bykonia, E.N.; Kozlova, S.R.; Evgrafova, E.A.; Zolotar, A.N.; Shidlovskaya, E.V.; Kirillova, E.S.; Krepkaia, A.S.; Usachev, E.V.; Kuznetsova, N.A.; Ivanov, I.A.; Dmitriev, S.E.; Ivanov, R.A.; Logunov, D.Y.; Gintsburg, A.L. Trivalent mRNA vaccine-candidate against seasonal flu with cross-specific humoral immune response. Frontiers in Immunology, 2024, 15, 1381508. doi: 10.3389/fimmu.2024.1381508
  146. Broering, M.F.; Oseliero Filho, P.L.; Borges, P.P.; da Silva, L.C.C.; Knirsch, M.C.; Xavier, L.F.; Scharf, P.; Sandri, S.; Stephano, M.A.; de Oliveira, F.A.; Sayed, I.M.; Gamarra, L.F.; Das, S.; Fantini, M.C.A.; Farsky, S.H.P. Development of Ac2-26 Mesoporous Microparticle System as a Potential Therapeutic Agent for Inflammatory Bowel Diseases. International Journal of Nanomedicine, 2024, 19, 3537-3554. doi: 10.2147/IJN.S451589
  147. Paul, S.; Arias, M.A.; Wen, L.; Liao, S.E.; Zhang, J.; Wang, X.; Regev, O.; Fei, J. RNA molecules display distinctive organization at nuclear speckles. iScience, 2024, 27(5), 109603. doi: 10.1016/j.isci.2024.109603
  148. Niu, L.; Jang, E.; Chin, A.L.; Huo, Z.; Wang, W.; Cai, W.; Tong, R. Noncovalently particle-anchored cytokines with prolonged tumor retention safely elicit potent antitumor immunity. Science Advances, 2024, 10(16), eadk7695. doi: 10.1126/sciadv.adk7695
  149. Mitchell, M.I.; Ben‐Dov, I.Z.; Ye, K.; Liu, C.; Shi, M.; Sadoughi, A.; Shah, C.; Siddiqui, T.; Okorozo, A.; Gutierrez, M.; Unawane, R.; Biamonte, L.; Parihk, K.; Spivack, S.; Loudig, O. Exhaled breath condensate contains extracellular vesicles (EVs) that carry miRNA cargos of lung tissue origin that can be selectively purified and analyzed. Journal of Extracellular Vesicles, 2024, 13(4), e12440. doi: 10.1002/jev2.12440
  150. Singh, A.; Lofts, A.; Krishnan, R.; Campea, M.; Chen, L.; Wan, Y.; Hoare, T. The effect of comb length on the in vitro and in vivo properties of self-assembled poly(oligoethylene glycol methacrylate)-based block copolymer nanoparticles † † Electronic supplementary information (ESI) available. See DOI: https://doi.org/10.1039/d3na01156a. Nanoscale Advances, 2024, 6(9), 2487-2498. doi: 10.1039/d3na01156a
  151. Chen, J.; Wang, B.; Wang, Y.; Radermacher, H.; Qi, J.; Momoh, J.; Lammers, T.; Shi, Y.; Rix, A.; Kiessling, F. mRNA Sonotransfection of Tumors with Polymeric Microbubbles: Co‐Formulation versus Co‐Administration. Advanced Science, 2024, 11(15), 2306139. doi: 10.1002/advs.202306139
  152. Mikheeva, A.M.; Bogomolov, M.A.; Gasca, V.A.; Sementsov, M.V.; Spirin, P.V.; Prassolov, V.S.; Lebedev, T.D. Improving the power of drug toxicity measurements by quantitative nuclei imaging. Cell Death Discovery, 2024, 10, 181. doi: 10.1038/s41420-024-01950-3
  153. Cheon, S.Y.; Park, J.S.; Lee, Y.; Lee, C.; Jeon, H.; Lee, D.; Kim, S.H.; Lim, S.G.; Koo, H. Injectable and Self‐Curing Single‐Component Hydrogel for Stem Cell Encapsulation and In Vivo Bone Regeneration. Advanced Science, 2024, 11(16), 2304861. doi: 10.1002/advs.202304861
  154. Kladova, O.A.; Tyugashev, T.E.; Yakimov, D.V.; Mikushina, E.S.; Novopashina, D.S.; Kuznetsov, N.A.; Kuznetsova, A.A. The Impact of SNP-Induced Amino Acid Substitutions L19P and G66R in the dRP-Lyase Domain of Human DNA Polymerase β on Enzyme Activities. International Journal of Molecular Sciences, 2024, 25(8), 4182. doi: 10.3390/ijms25084182
  155. Baranova, A.A.; Zakalyukina, Y.V.; Tyurin, A.P.; Korshun, V.A.; Belozerova, O.A.; Biryukov, M.V.; Moiseenko, A.V.; Terekhov, S.S.; Alferova, V.A. Antimicrobial Metabolites from Pig Nasal Microbiota. Russian Journal of Bioorganic Chemistry, 2024, 50(2), 354-374. doi: 10.1134/s1068162024020237
  156. Lee, J.J.; Kim, H.; Park, H.; Lee, U.J.; Kim, C.; Lee, M.; Shin, Y.; Jung, J.-J.; Lee, H.-B.; Han, W.; Lee, H. Disruption of G-quadruplex dynamicity by BRCA2 abrogation instigates phase separation and break-induced replication at telomeres. Nucleic Acids Research, 2024, gkae251. doi: 10.1093/nar/gkae251
  157. Mitchell, M.I.; Ben-Dov, I.Z.; Liu, C.; Wang, T.; Hazan, R.B.; Bauer, T.L.; Zakrzewski, J.; Donnelly, K.; Chow, K.; Ma, J.; Loudig, O. Non-invasive detection of orthotopic human lung tumors by microRNA expression profiling of mouse exhaled breath condensates and exhaled extracellular vesicles. Extracellular Vesicles and Circulating Nucleic Acids, 2024, 5(1), 138-64. doi: 10.20517/evcna.2023.77
  158. Tyumentseva, A.; Khilazheva, E.; Petrova, V.; Stolyar, S. Effects of iron oxide nanoparticles on the gene expression profiles of cerebral endotheliocytes and astrocytes. Toxicology in Vitro, 2024, 98, 105829. doi: 10.1016/j.tiv.2024.105829
  159. Deskeuvre, M.; Lan, J.; Messens, J.; Riant, O.; Feron, O.; Frédérick, R. A novel approach to pH-Responsive targeted cancer Therapy: Inhibition of FaDu cancer cell proliferation with a pH low insertion Peptide-Conjugated DGAT1 inhibitor. International Journal of Pharmaceutics, 2024, 657, 124132. doi: 10.1016/j.ijpharm.2024.124132
  160. Valeeva, E.V.; Sabirov, I.S.; Safiullina, L.R.; Nikitin, D.O.; Semina, I.I.; Rees, T.; Fesenko, D.O.; Ahmetov, I.I. The role of the CNTNAP2 gene in the development of autism spectrum disorder. Research in Autism Spectrum Disorders, 2024, 114, 102409. doi: 10.1016/j.rasd.2024.102409
  161. Horvat, N. K.; Chocarro, S.; Marques, O.; Bauer, T. A.; Qiu, R.; Diaz-Jimenez, A.; Helm, B.; Chen, Y.; Sawall, S.; Sparla, R.; Su, L.; Klingmüller, U.; Barz, M.; Hentze, M. W.; Sotillo, R.; Muckenthaler, M. U. Superparamagnetic Iron Oxide Nanoparticles Reprogram the Tumor Microenvironment and Reduce Lung Cancer Regrowth after Crizotinib Treatment. ACS Nano, 2024, 18(17), 11025–11041. doi: 10.1021/acsnano.3c08335
  162. Ebrahimimojarad, A.; Wang, Z.; Zhang, Q.; Shah, A.; Brenner, J. S.; Fu, J. A Robust and Efficient Method to Purify DNA-Scaffolded Nanostructures by Gravity-Driven Size Exclusion Chromatography. Langmuir, 2024, 40(16), 8365–8372. doi: 10.1021/acs.langmuir.3c03778
  163. Tamura, T.; McCann, P. C.; Nishiyama, R.; Hiramatsu, K.; Goda, K. Fluorescence-Encoded Time-Domain Coherent Raman Spectroscopy in the Visible Range. J. Phys. Chem. Lett, 2024, 15, 4940–4947. doi: 10.1021/acs.jpclett.4c00817
  164. Awah, C.U.; Sun Mun, J.; Paragodaarachchi, A.; Boylu, B.; Nzegwu, M.; Matsui, H.; Ogunwobi, O. Nanocage-incorporated engineered destabilized 3'UTR ARE of ERBB2 inhibits tumor growth and liver and lung metastasis in EGFR T790M osimertinib- and trastuzumab-resistant and ERBB2-expressing NSCLC via the reduction of ERBB2. Frontiers in Oncology, 2024, 14, 1344852. doi: 10.3389/fonc.2024.1344852
  165. Heesink, G.; van den Oetelaar, M.C.M.; Semerdzhiev, S.A.; Ottmann, C.; Brunsveld, L.; Blum, C.; Claessens, M.M.A.E. 14-3-3τ as a Modulator of Early α-Synuclein Multimerization and Amyloid Formation. ACS Chemical Neuroscience, 2024, 15(9), 1926-1936. doi: 10.1021/acschemneuro.4c00100
  166. Swan, J.; Szabó, Z.; Peters, J.; Kummu, O.; Kemppi, A.; Rahtu-Korpela, L.; Konzack, A.; Hakkola, J.; Pasternack, A.; Ritvos, O.; Kerkelä, R.; Magga, J. Inhibition of activin receptor 2 signalling ameliorates metabolic dysfunction–associated steatotic liver disease in western diet/L-NAME induced cardiometabolic disease. Biomedicine & Pharmacotherapy, 2024, 175, 116683. doi: 10.1016/j.biopha.2024.116683
  167. Nyberg, K.G.; Navales, F.G.; Keles, E.; Nguyen, J.Q.; Hertz, L.M.; Carthew, R.W. Robust and heritable knockdown of gene expression using a self-cleaving ribozyme in Drosophila. GENETICS, 2024, iyae067. doi: 10.1093/genetics/iyae067
  168. Liu, Q.; Wang, C.; Zhu, M.; Liu, J.; Duan, Q.; Midgley, A.C.; Liu, R.; Jiang, B.; Kong, D.; Chen, Q.; Zhuang, J.; Huang, X. Self‐Assembly of Heterogeneous Ferritin Nanocages for Tumor Uptake and Penetration. Advanced Science, 2024, 11(17), 2309271. doi: 10.1002/advs.202309271
  169. Takahashi, S.; Homma, K. The molecular principles underlying diverse functions of the SLC26 family of proteins. The Journal of Biological Chemistry, 2024, 300(5), 107261. doi: 10.1016/j.jbc.2024.107261
  170. Zhao, J.; Elgeti, M.; O’Brien, E.S.; Sár, C.P.; EI Daibani, A.; Heng, J.; Sun, X.; White, E.; Che, T.; Hubbell, W.L.; Kobilka, B.K.; Chen, C. Ligand efficacy modulates conformational dynamics of the µ-opioid receptor. Nature, 2024, 629(8011), 474-480. doi: 10.1038/s41586-024-07295-2
  171. Ernst, M.; Orabi, E.A.; Stockbridge, R.B.; Faraldo-Gómez, J.D.; Robertson, J.L. Dimerization mechanism of an inverted-topology ion channel in membranes. Proceedings of the National Academy of Sciences of the United States of America, 2024, 120(47), e2308454120. doi: 10.1073/pnas.2308454120
  172. Chiglintseva, D.; Clarke, D.J.; Sen'kova, A.; Heyman, T.; Miroshnichenko, S.; Shan, F.; Vlassov, V.; Zenkova, M.; Patutina, O.; Bichenkova, E. Engineering supramolecular dynamics of self-assembly and turnover of oncogenic microRNAs to drive their synergistic destruction in tumor models. Biomaterials, 2024, 309, 122604. doi: 10.1016/j.biomaterials.2024.122604
  173. Li, Y.; Qian, M.; Liu, Y.; Qiu, X. APPROACH: Sensitive Detection of Exosomal Biomarkers by Aptamer-Mediated Proximity Ligation Assay and Time-Resolved Förster Resonance Energy Transfer. Biosensors, 2024, 14(5), 233. doi: 10.3390/bios14050233
  174. Bonanno Ferraro, G.; Bonomo, C.; Brandtner, D.; Mancini, P.; Veneri, C.; Briancesco, R.; Coccia, A.M.; Lucentini, L.; Suffredini, E.; Bongiorno, D.; Musso, N.; Stefani, S.; La Rosa, G. Characterisation of microbial communities and quantification of antibiotic resistance genes in Italian wastewater treatment plants using 16S rRNA sequencing and digital PCR. Science of The Total Environment, 2024, 933, 173217. doi: 10.1016/j.scitotenv.2024.173217
  175. Yeoh, Y.Q.; Amin, A.; Cuic, B.; Tomas, D.; Turner, B.J.; Shabanpoor, F. Efficient systemic CNS delivery of a therapeutic antisense oligonucleotide with a blood-brain barrier-penetrating ApoE-derived peptide. Biomedicine & Pharmacotherapy, 2024, 175, 116737. doi: 10.1016/j.biopha.2024.116737
  176. Shang, Z.; Zhang, S.; Wang, J.; Zhou, L.; Zhang, X.; Billadeau, D.D.; Yang, P.; Zhang, L.; Zhou, F.; Bai, P.; Jia, D. TRIM25 predominately associates with anti-viral stress granules. Nature Communications, 2024, 15, 4127. doi: 10.1038/s41467-024-48596-4
  177. Bytov, M.V.; Petrova, I.M.; Khatsko, S.L.; Sokolova, O.V.; Shkuratova, I.A. Protocol refinement for quenching autofluorescence of red blood cells in FFPE sections of organ samples from cattle, pigs and chickens. BIO Web of Conferences, 2024, 108, 01034. doi: 10.1051/bioconf/202410801034
  178. Gabashvili, A.N.; Alexandrushkina, N.A.; Mochalova, E.N.; Goliusova, D.V.; Sapozhnikova, E.N.; Makarevich, P.I.; Nikitin, P.I. Internalization of transferrin-tagged Myxococcus xanthus encapsulins into mesenchymal stem cells. Experimental Biology and Medicine, 2024, 249(3), 10055. doi: 10.3389/ebm.2024.10055
  179. Pershina, A.G.; Efimova, L.V.; Brikunova, O.Y.; Nevskaya, K.V.; Sukhinina, E.V.; Hmelevskaya, E.S.; Demin, A.M.; Naumenko, V.A.; Malkeyeva, D.; Kiseleva, E.; Khozyainova, A.A.; Menyailo, M.E.; Denisov, E.V.; Volegov, A.S.; Uimin, M.A.; Krasnov, V.P.; Ogorodova, L.M. Nano-bio interaction of magnetic nanoparticles with cells in a tumor at the single-cell level. Nano Today, 2024, 56, 102300. doi: 10.1016/j.nantod.2024.102300
  180. Colville, M.J.; Huang, L.-T.; Schmidt, S.; Chen, K.; Vishwanath, K.; Su, J.; Williams, R.M.; Bonassar, L.J.; Reesink, H.L.; Paszek, M.J. Recombinant manufacturing of multispecies biolubricants. bioRxiv, 2024, preprint. doi: 10.1101/2024.05.05.592580
  181. Kladova, O.A.; Tyugashev, T.E.; Miroshnikov, A.A.; Novopashina, D.S.; Kuznetsov, N.A.; Kuznetsova, A.A. SNP-Associated Substitutions of Amino Acid Residues in the dNTP Selection Subdomain Decrease Polβ Polymerase Activity. Biomolecules, 2024, 14(5), 547. doi: 10.3390/biom14050547
  182. Mitchell, M.I.; Khalil, M.; Ben-Dov, I.Z.; Alverez-Perez, J.; Illsley, N.P.; Zamudio, S.; Al-Khan, A.; Loudig, O. Customizing EV-CATCHER to Purify Placental Extracellular Vesicles from Maternal Plasma to Detect Placental Pathologies. International Journal of Molecular Sciences, 2024, 25(10), 5102. doi: 10.3390/ijms25105102
  183. Kanaan, M.N.; Pileggi, C.A.; Karam, C.Y.; Kennedy, L.S.; Fong-McMaster, C.; Cuperlovic-Culf, M.; Harper, M.-E. Cystine/Glutamate Antiporter xCT Controls Skeletal Muscle Glutathione Redox, Bioenergetics and Differentiation. Redox Biology, 2024, 73, 103213. doi: 10.1016/j.redox.2024.103213
  184. Yu, T.; Hou, D.; Zhao, J.; Lu, X.; Greentree, W.K.; Zhao, Q.; Yang, M.; Conde, D.-G.; Linder, M.E.; Lin, H. NLRP3 Cys126 palmitoylation by ZDHHC7 promotes inflammasome activation. Cell reports, 2024, 43(4), 114070. doi: 10.1016/j.celrep.2024.114070
  185. Huang, Y.; Wang, J.; Mancino, V.; Pham, J.; O’Grady, C.; Li, H.; Jiang, K.; Chin, D.; Poon, C.; Ho, P.-Y.; Gyarmati, G.; Peti-Peterdi, J.; Hallows, K.R.; Chung, E.J. Oral delivery of nanomedicine for genetic kidney disease. PNAS Nexus, 2024, 3(5), pgae187. doi: 10.1093/pnasnexus/pgae187
  186. ten Hove, M.; Smyris, A.; Booijink, R.; Wachsmuth, L.; Hansen, U.; Alic, L.; Faber, C.; Hӧltke, C.; Bansal, R. Engineered SPIONs functionalized with endothelin a receptor antagonist ameliorate liver fibrosis by inhibiting hepatic stellate cell activation. Bioactive Materials, 2024, 39, 406-426. doi: 10.1016/j.bioactmat.2024.05.034
  187. Feng, J.; Chuah, Y.H.; Liang, Y.; Cipta, N.O.; Zeng, Y.; Warrier, T.; Elfar, G.A.R.E.; Yoon, J.; Grinchuk, O.V.; Tay, E.X.Y.; Lok, K.-Z.; Zheng, Z.-Q.; Khong, Z.J.; Chong, Z.-S.; Teo, J.; Sanford, E.M.; Neo, C.J.Y.; Chiu, H.Y.; Leung, J.Y.; Wang, L.C.; Lim, Y.T.; Zhao, T.; Sobota, R.M.; Crasta, K.C.; Tergaonkar, V.; Taneja, R.; Ng, S.-Y.; Cheok, C.F.; Ling, S.-C.; Loh, Y.-H.; Ong, D.S.T. PHF2 regulates genome topology and DNA replication in neural stem cells via cohesin. Nucleic Acids Research, 2024, gkae457. doi: 10.1093/nar/gkae457
  188. Barclay, K.M.; Abduljawad, N.; Cheng, Z.; Kim, M.W.; Zhou, L.; Yang, J.; Rustenhoven, J.; Mazzitelli, J.A.; Smyth, L.C.D.; Kapadia, D.; Brioschi, S.; Beatty, W.; Hou, J.C.; Saligrama, N.; Colonna, M.; Yu, G.; Kipnis, J.; Li, Q. An inducible genetic tool to track and manipulate specific microglial states reveals their plasticity and roles in remyelination. Immunity, 2024. doi: 10.1016/j.immuni.2024.05.005
  189. Lysakova, E.V.; Shumeev, A.N.; Chuvpilo, S.A.; Laktyushkin, V.S.; Arsentieva, N.A.; Bobrov, M.Y..; Rybtsov, S.A. Quantitative Analysis of Phagocytosis in Whole Blood Using Double Staining and Visualization. Biochemistry Moscow, 2024, 89(5), 923-932. doi: 10.1134/s0006297924050122
  190. Rak, A.; Matyushenko, V.; Prokopenko, P.; Kostromitina, A.; Polyakov, D.; Sokolov, A.; Rudenko, L.; Isakova-Sivak, I. A novel immunofluorescent test system for SARS-CoV-2 detection in infected cells. PLOS ONE, 2024, 19(5), e0304534. doi: 10.1371/journal.pone.0304534
  191. Yin, M.; Lei, D.; Liu, Y.; Qin, T.; Gao, H.; Lv, W.; Liu, Q.; Qin, L.; Jin, W.; Chen, Y.; Liang, H.; Wang, B.; Gao, M.; Zhang, J.; Lu, J. NIR triggered polydopamine coated cerium dioxide nanozyme for ameliorating acute lung injury via enhanced ROS scavenging. Journal of Nanobiotechnology, 2024, 22, 321. doi: 10.1186/s12951-024-02570-w
  192. Rana, H.; Truong, N.R.; Johnson, B.; Baharlou, H.; Herbert, J.J.; Kandasamy, S.; Goddard, R.; Cohen, R.C.; Wines, M.; Nasr, N.; Harman, A.N.; Bertram, K.M.; Sandgren, K.J.; Cunningham, A.L. Herpes simplex virus spreads rapidly in human foreskin, partly driven by chemokine-induced redistribution of Nectin-1 on keratinocytes. PLOS Pathogens, 2024, 20(6), e1012267. doi: 10.1371/journal.ppat.1012267
  193. Akam-Baxter, E.A.; Bergemann, D.; Ridley, S.J.; To, S.; Andrea, B.; Moon, B.; Ma, H.; Zhou, Y.; Aguirre, A.; Caravan, P.; Gonzalez-Rosa, J.M.; Sosnovik, D.E. Dynamics of collagen oxidation and cross linking in regenerating and irreversibly infarcted myocardium. Nature Communications, 2024, 15, 4648. doi: 10.1038/s41467-024-48604-7
  194. Son, T.; Kim, M.; Choi, M.; Nam, S.H.; Yoo, A.; Lee, H.; Han, E.H.; Hong, K.S.; Park, H.S. Advancing fluorescence imaging: enhanced control of cyanine dye-doped silica nanoparticles. Journal of Nanobiotechnology, 2024, 22, 347. doi: 10.1186/s12951-024-02638-7
  195. Zhong, L.; Zhang, W.; Liu, H.; Zhang, X.; Yang, Z.; Wen, Z.; Chen, L.; Chen, H.; Luo, Y.; Chen, Y.; Feng, Q.; Zeng, M.-S.; Zhao, Q.; Liu, L.; Krummenacher, C.; Zeng, Y.-X.; Chen, Y.; Xu, M.; Zhang, X. A cocktail nanovaccine targeting key entry glycoproteins elicits high neutralizing antibody levels against EBV infection. Nature Communications, 2024, 15, 5310. doi: 10.1038/s41467-024-49546-w
  196. Zhang, T.; Ai, D.; Wei, P.; Xu, Y.; Bi, Z.; Ma, F.; Li, F.; Chen, X.; Zhang, Z.; Zou, X.; Guo, Z.; Zhao, Y.; Li, J.-L.; Ye, M.; Feng, Z.; Zhang, X.; Zheng, L.; Yu, J.; Li, C.; Tu, T.; Zeng, H.; Lei, J.; Zhang, H.; Hong, T.; Zhang, L.; Luo, B.; Li, Z.; Xing, C.; Jia, C.; Li, L.; Sun, W.; Ge, W. The Subcommissural Organ Regulates Brain Development via Secreted Peptides. Nat Neurosci, 2024, 27(6), 1103–1115. doi: 10.1038/s41593-024-01639-x
  197. Huber, J.; Tanasie, N.-L.; Zernia, S.; Stigler, J. Single-molecule imaging reveals a direct role of CTCF’s zinc fingers in SA interaction and cluster-dependent RNA recruitment. Nucleic Acids Research, 2024, 52(11), 6490-6506. doi: 10.1093/nar/gkae391
  198. Li, J.; Tan, J.; Wang, T.; Yu, S.; Guo, G.; Li, K.; Yang, L.; Zeng, B.; Mei, X.; Gao, S.; Lao, X.; Zhang, S.; Liao, G.; Liang, Y. cGAS-ISG15-RAGE axis reprogram necroptotic microenvironment and promote lymphatic metastasis in head and neck cancer. Experimental Hematology & Oncology, 2024, 13, 63. doi: 10.1186/s40164-024-00531-5
  199. Lyamzaev, K.G.; Huan, H.; Panteleeva, A.A.; Simonyan, R.A.; Avetisyan, A.V.; Chernyak, B.V. Exogenous Iron Induces Mitochondrial Lipid Peroxidation, Lipofuscin Accumulation, and Ferroptosis in H9c2 Cardiomyocytes. Biomolecules, 2024, 14(6), 730. doi: 10.3390/biom14060730
  200. Grumov, D.; Kostarnoy, A.; Gancheva, P.; Kondratev, A. A Simple and Rapid Microscale Method for Isolating Bacterial Lipopolysaccharides. International Journal of Molecular Sciences, 2024, 25(12), 6345. doi: 10.3390/ijms25126345
  201. Guo, H.; Mukwaya, V.; Wu, D.; Xiong, S.; Dou, H. Acid-Responsive Decomposable Nanomedicine Based on Zeolitic Imidazolate Frameworks for Near-Infrared Fluorescence Imaging/Chemotherapy Combined Tumor Theranostics. Pharmaceutics, 2024, 16(6), 823. doi: 10.3390/pharmaceutics16060823
  202. van Veldhuisen, T.W.; Verwiel, M.A.M.; Novosedlik, S.; Brunsveld, L.; van Hest, J.C.M. Competitive protein recruitment in artificial cells. Communications Chemistry, 2024, 7, 148. doi: 10.1038/s42004-024-01229-9
  203. White, E.K.; Uberoi, A.; Pan, J.T.-C.; Ort, J.T.; Campbell, A.E.; Murga-Garrido, S.M.; Harris, J.C.; Bhanap, P.; Wei, M.; Robles, N.Y.; Gardner, S.E.; Grice, E.A. Alcaligenes faecalis corrects aberrant matrix metalloproteinase expression to promote reepithelialization of diabetic wounds. Science Advances, 2024, 10(26), eadj2020. doi: 10.1126/sciadv.adj2020
  204. Agnes, R.S.; Traughber, B.J.; Muzic, R.F. Development of a selective novel fluorescent substrate for sodium-dependent transporters. Life sciences, 2024, 351, 122847. doi: 10.1016/j.lfs.2024.122847
  205. Kang, N.-W.; Seo, Y.A.; Jackson, K.J.; Jang, K.; Song, E.; Han, U.; Chen, F.; Heilshorn, S.C.; Myung, D. Photoactivated growth factor release from bio-orthogonally crosslinked hydrogels for the regeneration of corneal defects. Bioactive Materials, 2024, 40, 417-429. doi: 10.1016/j.bioactmat.2024.05.045
  206. Fang, J.; Hurley, N.; Chien, C.T.; Guo, A.; Khan, T.A.; Li, M.; Cotlet, M.; Moretti, F.; Bourret, E.; Shifman, S.; Tsirka, S.E.; Shelly, M.; Wong, S.S. Probing the optical properties and toxicological profile of zinc tungstate nanorods. The Journal of Chemical Physics, 2024, 160(23), 234701. doi: 10.1063/5.0209935
  207. Liu, Y.; Sundah, N.R.; Ho, N.R.Y.; Shen, W.X.; Xu, Y.; Natalia, A.; Yu, Z.; Seet, J.E.; Chan, C.W.; Loh, T.P.; Lim, B.Y.; Shao, H. Bidirectional linkage of DNA barcodes for the multiplexed mapping of higher-order protein interactions in cells. Nature biomedical engineering, 2024, 8, 909–923. doi: 10.1038/s41551-024-01225-3
  208. Kodaka, M.; Kikuchi, A.; Kawahira, K.; Kamada, H.; Katsuta, R.; Ishigami, K.; Suzuki, T.; Yamamoto, Y.; Inoue, J. Identification of a novel target of sulforaphane: Sulforaphane binds to acyl-protein thioesterase 2 (APT2) and attenuates its palmitoylation. Biochemical and biophysical research communications, 2024, 726, 150244. doi: 10.1016/j.bbrc.2024.150244
  209. Lebedeva, D.A.; Igonina, T.N.; Brusentsev, E.Y..; Shavshaeva, N.A.; Amstislavsky, S.Y.. Effects of Ovarian Gonadotropin Stimulation under Conditions of Chronic Psychosocial Stress on the Quality of Murine Oocytes. Journal of Evolutionary Biochemistry and Physiology, 2024, 60(3), 1175-1186. doi: 10.1134/s0022093024030244
  210. Bayon, J.L.; Shih, C.; Craig, S.L.; Steinmetz, N.F. A simple swell-and-click method for the covalent attachment of virus-like particles to polymer hydrogels. Materials Today Chemistry, 2024, 38, 102100. doi: 10.1016/j.mtchem.2024.102100
  211. Anisimova, D.O.; Savchenko, M.S.; Tuzikov, A.B.; Paramonov, A.S.; Chizhov, A.O.; Bovin, N.V.; Ryzhov, I.M. Synthesis of Bifunctional Lipophilic Constructs. Russian Journal of Bioorganic Chemistry, 2024, 50(3), 681-695. doi: 10.1134/s1068162024030105
  212. Suwatthanarak, T.; Tanjak, P.; Chaiboonchoe, A.; Acharayothin, O.; Thanormjit, K.; Chanthercrob, J.; Suwatthanarak, T.; Niyomchan, A.; Tanaka, M.; Okochi, M.; Pongpaibul, A.; Chalermwai, W.V.; Trakarnsanga, A.; Methasate, A.; Pithukpakorn, M.; Chinswangwatanakul, V. Overexpression of TSPAN8 in consensus molecular subtype 3 colorectal cancer. Experimental and molecular pathology, 2024, 137, 104911. doi: 10.1016/j.yexmp.2024.104911
  213. Xiang, Y.; Zhao, Z.; Yao, E.J.; Balayan, A.; Fiering, S.N.; Steinmetz, N.F.; Chen, S. Multifaceted cancer alleviation by cowpea mosaic virus in a bioprinted ovarian cancer peritoneal spheroid model. Biomaterials, 2024, 311, 122663. doi: 10.1016/j.biomaterials.2024.122663
  214. Kusmierczyk, J.; Wiecek, M.; Bawelski, M.; Szygula, Z.; Rafa-Zablocka, K.; Kantorowicz, M.; Szymura, J. Pre-exercise cryotherapy reduces myoglobin and creatine kinase levels after eccentric muscle stress in young women. Frontiers in Physiology, 2024, 15, 1413949. doi: 10.3389/fphys.2024.1413949
  215. Krasnikov, N.; Rykova, V.; Kucheruk, O.; Komina, A.; Pchelnikov, A.; Gulyukin, A.; Yuzhakov, A. Genetic diversity of porcine circoviruses 2 and 3 circulating among wild boars in the Moscow Region of Russia. Frontiers in Veterinary Science, 2024, 11, 1372203. doi: 10.3389/fvets.2024.1372203
  216. Haynes, J.R.; Whitmore, C.A.; Behof, W.J.; Landman, C.A.; Ong, H.H.; Feld, A.P.; Suero, I.C.; Greer, C.B.; Gore, J.C.; Wijesinghe, P.; Matsubara, J.A.; Wadzinski, B.E.; Spiller, B.W.; Pham, W. Targeting soluble amyloid-beta oligomers with a novel nanobody. Scientific Reports, 2024, 14, 16086. doi: 10.1038/s41598-024-66970-6
  217. Koryukov, M.A.; Oscorbin, I.P.; Novikova, L.M.; Gordukova, M.A.; Turina, I.E.; Galeeva, E.V.; Kudlay, D.A.; Filipenko, M.L. A Novel Multiplex LAMP Assay for the Detection of Respiratory Human Adenoviruses. International Journal of Molecular Sciences, 2024, 25(13), 7215. doi: 10.3390/ijms25137215
  218. Lebedeva, N.A.; Anarbaev, R.O.; Maltseva, E.A.; Sukhanova, M.V.; Rechkunova, N.I.; Lavrik, O.I. DNA Repair Protein XRCC1 Stimulates Activity of DNA Polymerase λ under Conditions of Microphase Separation. International Journal of Molecular Sciences, 2024, 25(13), 6927. doi: 10.3390/ijms25136927
  219. Dan, Y.; Gurevich, D.; Gershoni, O.; Netti, F.; Adler-Abramovich, L.; Afriat-Jurnou, L. Coupling Peptide-Based Encapsulation of Enzymes with Bacteria for Paraoxon Bioremediation. ACS Applied Materials & Interfaces, 2024, 16(27), 35155-35165. doi: 10.1021/acsami.4c06501
  220. Colli, C.; Masi, I.; Jacchetti, E.; Santoni, S.; Sponchioni, M.; Colosimo, B.M.; Rosanò, L.; Raimondi, M.T.; Mauri, E.; Moscatelli, D. Zwitterionic nanoparticles for thermally activated drug delivery in hyperthermia cancer treatment. Nanoscale, 2024, 16(26), 12635-12649. doi: 10.1039/d4nr00723a
  221. Epshtein, M.; Gounis, M.J.; Bogdanov, A.A. X-ray Attenuating Vesicles with Neutrophil Extracellular Trap (NET) Specificity: Synthesis and Testing in a Model System. ACS Omega, 2024, 9(27), 29391-29400. doi: 10.1021/acsomega.4c01525
  222. Kumar Podder, A.; Mohamed, M.A.; Seidman, R.A.; Tseropoulos, G.; Polanco, J.J.; Lei, P.; Sim, F.J.; Andreadis, S.T. Injectable shear-thinning hydrogels promote oligodendrocyte progenitor cell survival and remyelination in the central nervous system. Science Advances, 2024, 10(28), eadk9918. doi: 10.1126/sciadv.adk9918
  223. Hernandez, K.C.; Shah, A.M.; Lopez, V.A.; Tagliabracci, V.S.; Chen, K.; Xu, L.; Bassel-Duby, R.; Olson, E.N.; Liu, N. CD73 contributes to the pathogenesis of fusion-negative rhabdomyosarcoma through the purinergic signaling pathway. Proceedings of the National Academy of Sciences of the United States of America, 2024, 121(4), e2315925121. doi: 10.1073/pnas.2315925121
  224. Shirakura, T.; Krishnamoorthy, L.; Paliwal, P.; Hird, G.; McCluskie, K.; McWilliams, P.; He, M.; Ismaili, M.H.A. In vitro treatment with liposome-encapsulated Mannose-1-phosphate restores N-glycosylation in PMM2-CDG patient-derived fibroblasts. Molecular Genetics and Metabolism, 2024, 143(1-2), 108531. doi: 10.1016/j.ymgme.2024.108531
  225. Gryaznova, M.; Burakova, I.; Smirnova, Y.; Morozova, P.; Chirkin, E.; Gureev, A.; Mikhaylov, E.; Korneeva, O.; Syromyatnikov, M. Effect of Probiotic Bacteria on the Gut Microbiome of Mice with Lipopolysaccharide-Induced Inflammation. Microorganisms, 2024, 12(7), 1341. doi: 10.3390/microorganisms12071341
  226. Lu, X.; Passalacqua, L.F.M.; Nodwell, M.; Kong, K.Y.S.; Caballero-García, G.; Dolgosheina, E.V.; Ferré-D’Amaré, A.R.; Britton, R.; Unrau, P.J. Symmetry breaking of fluorophore binding to a G-quadruplex generates an RNA aptamer with picomolar KD. Nucleic Acids Research, 2024, gkae493. doi: 10.1093/nar/gkae493
  227. Kolesnikova, O.A.; Komedchikova, E.N.; Zvereva, S.D.; Obozina, A.S.; Dorozh, O.V.; Afanasev, I.; Nikitin, P.I.; Mochalova, E.N.; Nikitin, M.P.; Shipunova, V.O. Albumin incorporation into recognising layer of HER2-specific magnetic nanoparticles as a tool for optimal targeting of the acidic tumor microenvironment. Heliyon, 2024, 10(14), e34211. doi: 10.1016/j.heliyon.2024.e34211
  228. Sheshil, A.; Titov, A.; Grudtsov, V.; Gabdrakhmanov, A.; Ryazantsev, D.; Komarova, N. ISFET with CMOS IC Combined with DNA Aptamer to Detect NT-proBNP. 2024 IEEE Ural-Siberian Conference on Biomedical Engineering, Radioelectronics and Information Technology (USBEREIT), 2024, 178-181. doi: 10.1109/usbereit61901.2024.10583991
  229. Michalski, J.; Kalwarczyk, T.; Kwapiszewska, K.; Enderlein, J.; Poniewierski, A.; Karpińska, A.; Kucharska, K.; Hołyst, R. Rotational and translational diffusion of biomolecules in complex liquids and HeLa cells. Soft Matter, 2024, 20, 5810-5821. doi: 10.1039/d4sm00422a
  230. Li, C.; Wang, J.; Li, H.; Wang, Y.; Wu, H.; Wei, W.; Wu, D.; Shao, J.; Wang, T.; Wang, C. Suppressing the virulence factors of Candida auris with baicalein through multifaceted mechanisms. Archives of Microbiology, 2024, 206(8), 349. doi: 10.1007/s00203-024-04038-9
  231. Xing, W.; Li, D.; Wang, W.; Liu, J.-J.G.; Chen, C. Conformational dynamics of CasX (Cas12e) in mediating DNA cleavage revealed by single-molecule FRET. Nucleic Acids Research, 2024. doi: 10.1093/nar/gkae604
  232. Borisova, E.; Newman, A. G.; Couce Iglesias, M.; Dannenberg, R.; Schaub, T.; Qin, B.; Rusanova, A.; Brockmann, M.; Koch, J.; Daniels, M.; Turko, P.; Jahn, O.; Kaplan, D. R.; Rosário, M.; Iwawaki, T.; Spahn, C. M. T.; Rosenmund, C.; Meierhofer, D.; Kraushar, M. L.; Tarabykin, V.; Ambrozkiewicz, M. C. Protein Translation Rate Determines Neocortical Neuron Fate. Nat Commun, 2024, 15(1), 4879. doi: 10.1038/s41467-024-49198-w
  233. Valentino, I. M.; Llivicota-Guaman, J. G.; Dao, T. P.; Mulvey, E. O.; Lehman, A. M.; Galagedera, S. K. K.; Mallon, E. L.; Castañeda, C. A.; Kraut, D. A. Phase Separation of Polyubiquitinated Proteins in UBQLN2 Condensates Controls Substrate Fate. Proceedings of the National Academy of Sciences, 2024, 121(33), e2405964121. doi: 10.1073/pnas.2405964121
  234. Xia, Q.; Perera, H. A.; Bolarinho, R.; Piskulich, Z. A.; Guo, Z.; Yin, J.; He, H.; Li, M.; Ge, X.; Cui, Q.; Ramström, O.; Yan, M.; Cheng, J.-X. Click-Free Imaging of Carbohydrate Trafficking in Live Cells Using an Azido Photothermal Probe. Science Advances, 2024, 10(34), eadq0294. doi: 10.1126/sciadv.adq0294
  235. Cardenas, A. J.; Thomas, K. S.; Broden, M. W.; Ferraro, N. J.; Pires, M. M.; John, C. M.; Jarvis, G. A.; Criss, A. K. Neisseria Gonorrhoeae Scavenges Host Sialic Acid for Siglec-Mediated, Complement-Independent Suppression of Neutrophil Activation. mBio, 2024, 15(5), e00119-24. doi: 10.1128/mbio.00119-24
  236. Haugen, R. J.; Barnier, C.; Elrod, N. D.; Luo, H.; Jensen, M. K.; Ji, P.; Smibert, C. A.; Lipshitz, H. D.; Wagner, E. J.; Freddolino, P. L.; Goldstrohm, A. C. Regulation of the Drosophila Transcriptome by Pumilio and the CCR4–NOT Deadenylase Complex. RNA, 2024, 30(7), 866–890. doi: 10.1261/rna.079813.123
  237. Soxpollard, N.; Strauss, S.; Jungmann, R.; MacPherson, I. S. Selection of Antibody-Binding Covalent Aptamers. Commun Chem, 2024, 7(1), 1-11. doi: 10.1038/s42004-024-01255-7
  238. Afting, C.; Walther, T.; Drozdowski, O. M.; Schlagheck, C.; Schwarz, U. S.; Wittbrodt, J.; Göpfrich, K. DNA Microbeads for Spatio-Temporally Controlled Morphogen Release within Organoids. Nat. Nanotechnol., 2024, 1-9. doi: 10.1038/s41565-024-01779-y
  239. Miao, L.; Yu, C.; Guan, G.; Luan, X.; Jin, X.; Pan, M.; Yang, Y.; Yan, J.; Chen, P.; Di, G. Extracellular Vesicles Containing GAS6 Protect the Liver from Ischemia-Reperfusion Injury by Enhancing Macrophage Efferocytosis via MerTK-ERK-COX2 Signaling. Cell Death Discov., 2024, 10(1), 1–13. doi: 10.1038/s41420-024-02169-y
  240. Wu, J.; Xiao, Y.; Liu, Y.; Wen, L.; Jin, C.; Liu, S.; Paul, S.; He, C.; Regev, O.; Fei, J. Dynamics of RNA Localization to Nuclear Speckles Are Connected to Splicing Efficiency. Science Advances, 2024, 10(42), eadp7727. doi: 10.1126/sciadv.adp7727
  241. Krasikova, A.; Kulikova, T.; Schelkunov, M.; Makarova, N.; Fedotova, A.; Plotnikov, V.; Berngardt, V.; Maslova, A.; Fedorov, A. The First Chicken Oocyte Nucleus Whole Transcriptomic Profile Defines the Spectrum of Maternal MRNA and Non-Coding RNA Genes Transcribed by the Lampbrush Chromosomes. Nucleic Acids Research, 2024, 52(21), 12850–12877. doi: 10.1093/nar/gkae941
  242. Toro-González, M.; Akingbesote, N.; Bible, A.; Pal, D.; Sanders, B.; Ivanov, A. S.; Jansone-Popova, S.; Popovs, I.; Benny, P.; Perry, R.; Davern, S. Development of 255Ac-Doped Biocompatible Nanoparticles for Targeted Alpha Therapy. Journal of Nanobiotechnology, 2024, 22(1), 306. doi: 10.1186/s12951-024-02520-6
  243. Ayala-Orozco, C.; Li, G.; Li, B.; Vardanyan, V.; Kolomeisky, A. B.; Tour, J. M. How to Build Plasmon-Driven Molecular Jackhammers That Disassemble Cell Membranes and Cytoskeletons in Cancer. Advanced Materials, 2024, 36(14), 2309910. doi: 10.1002/adma.202309910
  244. Lercher, A.; Cheong, J.-G.; Bale, M. J.; Jiang, C.; Hoffmann, H.-H.; Ashbrook, A. W.; Lewy, T.; Yin, Y. S.; Quirk, C.; DeGrace, E. J.; Chiriboga, L.; Rosenberg, B. R.; Josefowicz, S. Z.; Rice, C. M. Antiviral Innate Immune Memory in Alveolar Macrophages Following SARS-CoV-2 Infection Ameliorates Secondary Influenza A Virus Disease. Immunity, 2024, 57(11), 2530-2546.e13. doi: 10.1016/j.immuni.2024.08.018
  245. Miller, M. A.; Medina, S. Synthetic Colonic Mucus Enables the Development of Modular Microbiome Organoids. Advanced Functional Materials, 2024, 34(38), 2402514. doi: 10.1002/adfm.202402514
  246. Lin, R.; Wang, Y. Developing Multichannel SmFRET Approach to Dissecting Ribosomal Mechanisms. Chemical & Biomedical Imaging, 2024, 2(7), 501–509. doi: 10.1021/cbmi.4c00010
  247. Kovshova, T.; Malinovskaya, J.; Kotova, J.; Gorshkova, M.; Vanchugova, L.; Osipova, N.; Melnikov, P.; Vadekhina, V.; Nikitin, A.; Ermolenko, Y.; Gelperina, S. Core–Shell PLGA Nanoparticles: In Vitro Evaluation of System Integrity. Biomolecules, 2024, 14(12), 1601. doi: 10.3390/biom14121601
  248. Grigorenko, V.G.; Krivitskaya, A.V.; Khrenova, M.G.; Rubtsova, M.Y..; Presnova, G.V.; Andreeva, I.P.; Serova, O.V.; Egorov, A.M. Saturation Mutagenesis and Molecular Modeling: The Impact of Methionine 182 Substitutions on the Stability of β-Lactamase TEM-1. International Journal of Molecular Sciences, 2024, 25(14), 7691. doi: 10.3390/ijms25147691
  249. Leshchenko, E.V.; Chingizova, E.A.; Antonov, A.S.; Shlyk, N.P.; Borkunov, G.V.; Berdyshev, D.V.; Chausova, V.E.; Kirichuk, N.N.; Khudyakova, Y.V.; Chingizov, A.R.; Kalinovsky, A.I.; Popov, R.S.; Kim, N.Y..; Chadova, K.A.; Yurchenko, E.A.; Isaeva, M.P.; Yurchenko, A.N. New Zosteropenillines and Pallidopenillines from the Seagrass-Derived Fungus Penicillium Yezoense KMM 4679. Marine Drugs, 2024, 22(7), 317. doi: 10.3390/md22070317
  250. Xu, H.; Yu, P.; Bandari, R.P.; Smith, C.J.; Aro, M.R.; Singh, A.; Ma, L. Bimodal MRI/Fluorescence Nanoparticle Imaging Contrast Agent Targeting Prostate Cancer. Nanomaterials, 2024, 14(14), 1177. doi: 10.3390/nano14141177
  251. Sindeeva, O.A.; Demina, P.A.; Kozyreva, Z.V.; Terentyeva, D.A.; Gusliakova, O.I.; Muslimov, A.R.; Sukhorukov, G.B. Single Mesenchymal Stromal Cell Migration Tracking into Glioblastoma Using Photoconvertible Vesicles. Nanomaterials, 2024, 14(14), 1215. doi: 10.3390/nano14141215
  252. Stamm, S.M.; Wagner, R.; Lang, D.A.; Skerra, A.; Gebauer, M. Development of a Clonal and High-Yield Mammalian Cell Line for the Manufacturing of a Hyperactive Human DNase I with Extended Plasma Half-Life Using PASylation ® Technology. Pharmaceutics, 2024, 16(7), 967. doi: 10.3390/pharmaceutics16070967
  253. Walter, M.; Bresinsky, M.; Zimmer, O.; Pockes, S.; Goepferich, A. Conditional Cell-Penetrating Peptide Exposure as Selective Nanoparticle Uptake Signal. ACS Applied Materials & Interfaces, 2024, 16(29), 37734-37747. doi: 10.1021/acsami.4c07821
  254. Ryl, T.; Afanasyeva, E.; Hartmann, T.; Schwermer, M.; Schneider, M.; Schröder, C.; Wagemanns, M.; Bister, A.; Kanber, D.; Steenpass, L.; Schramm, K.; Jones, B.; Jones, D.T.W.; Biewald, E.; Astrahantseff, K.; Hanenberg, H.; Rahmann, S.; Lohmann, D.R.; Schramm, A.; Ketteler, P. A MYCN-driven de-differentiation profile identifies a subgroup of aggressive retinoblastoma. Communications Biology, 2024, 7, 919. doi: 10.1038/s42003-024-06596-6
  255. Han, X.; Lu, X.; Li, P.H.; Wang, S.; Schalek, R.; Meirovitch, Y.; Lin, Z.; Adhinarta, J.; Murray, K.D.; MacNiven, L.M.; Berger, D.R.; Wu, Y.; Fang, T.; Meral, E.S.; Asraf, S.; Ploegh, H.; Pfister, H.; Wei, D.; Jain, V.; Trimmer, J.S.; Lichtman, J.W. Multiplexed volumetric CLEM enabled by scFvs provides insights into the cytology of cerebellar cortex. Nature Communications, 2024, 15, 6648. doi: 10.1038/s41467-024-50411-z
  256. Herkert, E.K.; Lau, L.; Pons Lanau, R.; Garcia-Parajo, M.F. Hexagonal Plasmonic Arrays for High-Throughput Multicolor Single-Molecule Studies. ACS Applied Materials & Interfaces, 2024, 16(31), 41271-41280. doi: 10.1021/acsami.4c04744
  257. Awah, C.U.; Mun, J.S.; Paragodaarachchi, A.; Boylu, B.; Ochu, C.; Matsui, H.; Ogunwobi, O.O. The Engineered Drug 3′UTRMYC1-18 Degrades the c-MYC-STAT5A/B-PD-L1 Complex In Vivo to Inhibit Metastatic Triple-Negative Breast Cancer. Cancers, 2024, 16(15), 2663. doi: 10.3390/cancers16152663
  258. Shkodenko, L.A.; Mohamed, A.-A.; Ateiah, M.; Rubel, M.S.; Koshel, E.I. A DAMP-Based Assay for Rapid and Affordable Diagnosis of Bacterial Meningitis Agents: Haemophilus influenzae , Neisseria meningitidis , and Streptococcus pneumoniae. International Journal of Molecular Sciences, 2024, 25(15), 8282. doi: 10.3390/ijms25158282
  259. González-Sáenz, P.; Cosialls, R.; Texidó, R.; Dols-Pérez, A.; Cuenca, A.B.; Borrós, S.; Fornaguera, C. Designing Polyelectrolyte Microneedles Based on Borylated Poly(β-aminoester) Polymers To Enhance Transdermal pH-Controlled Delivery of Nucleic Acids. ACS Applied Polymer Materials, 2024, 6(15), 8842-8855. doi: 10.1021/acsapm.4c00969
  260. Chen, R.; Stainier, W.; Dufourt, J.; Lagha, M.; Lehmann, R. Direct observation of translational activation by a ribonucleoprotein granule. Nature cell biology, 2024, 26(8), 1322-1335. doi: 10.1038/s41556-024-01452-5
  261. van Bergen, W.; Žuna, K.; Fiala, J.; Pohl, E.E.; Heck, A.J.R.; Baggelaar, M.P. Dual-Probe Activity-Based Protein Profiling Reveals Site-Specific Differences in Protein Binding of EGFR-Directed Drugs. ACS Chemical Biology, 2024, 19(8), 1705-1718. doi: 10.1021/acschembio.3c00637
  262. Peña-Díaz, S.; Chao, J.D.; Rens, C.; Haghdadi, H.; Zheng, X.; Flanagan, K.; Ko, M.; Shapira, T.; Richter, A.; Maestre-Batlle, D.; Canseco, J.O.; Gutierrez, M.G.; Duc, K.D.; Pelech, S.; Av-Gay, Y. Glycogen synthase kinase 3 inhibition controls Mycobacterium tuberculosis infection. iScience, 2024, 27(8), 110555. doi: 10.1016/j.isci.2024.110555
  263. Frolov, A.V.; Vishnevskaya, M.S.; Viljanen, H.; Montreuil, O.; Akhmetova, L.A. New data on trophic associations of dung beetles ( Coleoptera , Scarabaeidae , Scarabaeinae ) and lemurs ( Primates , Lemuroidea ) in Madagascar revealed by metabarcoding. Biodiversity Data Journal, 2024, 12, e130400. doi: 10.3897/BDJ.12.e130400
  264. Liu, Y.; Hou, D.; Chen, W.; Lu, X.; Komaniecki, G.P.; Xu, Y.; Yu, T.; Zhang, S.M.; Linder, M.E.; Lin, H. MAVS Cys508 palmitoylation promotes its aggregation on the mitochondrial outer membrane and antiviral innate immunity. Proceedings of the National Academy of Sciences of the United States of America, 2024, 121(34), e2403392121. doi: 10.1073/pnas.2403392121
  265. Halim, A.; Al-Qadi, N.; Kenyon, E.; Conner, K.N.; Mondal, S.K.; Medarova, Z.; Moore, A. Inhibition of miR-10b treats metastatic breast cancer by targeting stem cell-like properties. Oncotarget, 2024, 15, 591-606. doi: 10.18632/oncotarget.28641
  266. Samatoshenkov, I.V.; Aimaletdinov, A.M.; Zakirova, E.Y.; Chelyshev, Y.A.; Samatoshenkova, J.M.; Kadyrov, M.S.; Kniazev, E.A.; Salakhov, B.I.; Mukhamedshina, Y.O. The Combined Delivery of the Vegf, Ang, and Gdnf Genes Stimulates Angiogenesis and Improves Post-Ischemic Innervation and Regeneration in Skeletal Muscle. Current Issues in Molecular Biology, 2024, 46(8), 8611-8626. doi: 10.3390/cimb46080507
  267. Menchinskaya, E. S.; Chingizova, E. A.; Pislyagin, E. A.; Yurchenko, E. A.; Klimovich, A. A.; Zelepuga, E. A.; Aminin, D. L.; Avilov, S. A.; Silchenko, A. S. Mechanisms of Action of Sea Cucumber Triterpene Glycosides Cucumarioside A0-1 and Djakonovioside A Against Human Triple-Negative Breast Cancer. Marine Drugs, 2024, 22(10), 474. doi: 10.3390/md22100474
  268. Chingizova, E. A.; Yurchenko, E. A.; Chingizov, A. R.; Klimovich, A. A.; Pislyagin, E. A.; Menchinskaya, E. S.; Kuzmich, A. S.; Trinh, P. T. H.; Ngoc, N. T. D.; Van, T. T. T.; Guzhova, I. V.; Aminin, D. L.; Yurchenko, A. N. The Effects of Marine Fungal Asterripeptides A–C on In Vitro and In Vivo Staphylococcus Aureus Skin Infection. Pharmaceuticals, 2024, 17(10), 1345. doi: 10.3390/ph17101345
  269. Chingizova, E. A.; Chingizov, A. R.; Menchinskaya, E. S.; Pislyagin, E. A.; Kuzmich, A. S.; Leshchenko, E. V.; Borkunov, G. V.; Guzhova, I. V.; Aminin, D. L.; Yurchenko, E. A. The Influence of Marine Fungal Meroterpenoid Meroantarctine A toward HaCaT Keratinocytes Infected with Staphylococcus Aureus. J Antibiot, 2024, 77(12), 812–822. doi: 10.1038/s41429-024-00771-x

2023

  1. Wang, Y. Ribozyme synthesis of both L- and D- amino acid oligos. bioRxiv, 2023, preprint. doi: 10.1101/2023.04.28.538729
  2. Knudsen, E. B.; Zappitelli, K.; Brown, J.; Reeder, J.; Smith, K. S.; Rostov, M.; Choi, J.; Rochford, A.; Slager, N.; Miura, S. K.; Rodgers, K.; Reed, A.; Lewis Israeli, Y. R.; Shiraga, S.; Seo, K. J.; Wolin, C.; Dawson, P.; Eltaeb, M.; Dasgupta, A.; Rothman, M.; Yoon, E.; Chong, P.; Charles, S.; Stewart, J. M.; Silva, R. A.; Kim, T.; Kong, Y.; Mardinly, A. R.; Hodak, M. A Thin-Film Optogenetic Visual Prosthesis. bioRxiv, 2023, preprint. doi: 10.1101/2023.01.31.526482
  3. Ramezani, M.; Bauman, J.; Singh, A.; Weisbart, E.; Yong, J.; Lozada, M.; Way, G.P.; Kavari, S.L.; Diaz, C.; Haghighi, M.; Batista, T.M.; Pérez-Schindler, J.; Claussnitzer, M.; Singh, S.; Cimini, B.A.; Blainey, P.C.; Carpenter, A.E.; Jan, C.H.; Neal, J.T. A genome-wide atlas of human cell morphology. bioRxiv, 2023. doi: 10.1101/2023.08.06.552164
  4. Kang, Z.; Fu, P.; Ma, H.; Li, T.; Lu, K.; Liu, J.; Ginjala, V.; Romanienko, P.; Feng, Z.; Guan, M.; Ganesan, S.; Xia, B. Distinct functions of EHMT1 and EHMT2 in cancer chemotherapy and immunotherapy. bioRxiv, 2023, preprint. doi: 10.1101/2023.10.03.560719
  5. Fong, C.K.; Andersen, M.J.; Kunesh, E.; Leonard, E.; Durand, D.; Coombs, R.; Flores-Mireles, A.L.; Howell, C. Removal of Free Liquid Layer from Liquid-Infused Catheters Reduces Silicone Loss into the Environment while Maintaining Adhesion Resistance. medRxiv, 2023, preprint. doi: 10.1101/2023.09.14.23295548
  6. Gentry, R.C.; Ide, N.A.; Comunale, V.M.; Hartwick, E.W.; Kinz-Thompson, C.D.; Gonzalez, R.L. The mechanism of mRNA activation. bioRxiv, 2023, preprint. doi: 10.1101/2023.11.15.567265
  7. Peterson, B. G.; Hwang, J.; Russ, J. E.; Schroeder, J. W.; Freddolino, P. L.; Baldridge, R. D. Deep Mutational Scanning Highlights a Role for Cytosolic Regions in Hrd1 Function. Cell Reports, 2023, 42(11), 113451. doi: 10.1016/j.celrep.2023.113451
  8. Ayala-Orozco, C.; Galvez-Aranda, D.; Corona, A.; Seminario, J. M.; Rangel, R.; Myers, J. N.; Tour, J. M. Molecular Jackhammers Eradicate Cancer Cells by Vibronic-Driven Action. Nature Chemistry, 2023. doi: 10.1038/s41557-023-01383-y
  9. Chadda, R.; Lee, T.; Mahoney-Kruszka, R.; Kelley, E. G.; Bernhardt, N.; Sandal, P.; Robertson, J. L. A Thermodynamic Analysis of CLC Transporter Dimerization in Lipid Bilayers. Proceedings of the National Academy of Sciences, 2023, 120(41), e2305100120. doi: 10.1073/pnas.2305100120
  10. Izzo, A.; Akol, I.; Villarreal, A.; Lebel, S.; Garcia-Miralles, M.; Cheffer, A.; Bovio, P.; Heidrich, S.; Vogel, T. Nucleophosmin 1 Cooperates with the Methyltransferase DOT1L to Preserve Peri-Nucleolar Heterochromatin Organization by Regulating H3K27me3 Levels and DNA Repeats Expression. Epigenetics & Chromatin, 2023, 16(1), 36. doi: 10.1186/s13072-023-00511-9
  11. Krasikova, A.; Kulikova, T.; Rodriguez Ramos, J. S.; Maslova, A. Assignment of the Somatic A/B Compartments to Chromatin Domains in Giant Transcriptionally Active Lampbrush Chromosomes. Epigenetics & Chromatin, 2023, 16(1), 24. doi: 10.1186/s13072-023-00499-2
  12. Kislova, A. V.; Zheglo, D.; Pozhitnova, V. O.; Sviridov, P. S.; Gadzhieva, E. P.; Voronina, E. S. Replication Stress Causes Delayed Mitotic Entry and Chromosome 12 Fragility at the ANKS1B Large Neuronal Gene in Human Induced Pluripotent Stem Cells. Chromosome Research, 2023, 31(3), 23. doi: 10.1007/s10577-023-09729-5
  13. Jaiswal, M.; Tran, T. T.; Guo, J.; Zhou, M.; Kundu, S.; Guo, Z.; Fanucci, G. E. Spin-Labeling Insights into How Chemical Fixation Impacts Glycan Organization on Cells. Appl Magn Reson, 2023. doi: 10.1007/s00723-023-01624-w
  14. Morrison, V.; Houpert, M.; Trapani, J.; Brockman, A.; Kingsley, P.; Katdare, K.; Layden, H.; Nguena-Jones, G.; Trevisan, A.; Maguire-Zeiss, K.; Marnett, L.; Bix, G.; Ihrie, R.; Carter, B. Jedi-1/MEGF12-Mediated Phagocytosis Controls the pro-Neurogenic Properties of Microglia in the Ventricular-Subventricular Zone. Cell Reports, 2023, 42(11), 113423. doi: 10.1016/j.celrep.2023.113423
  15. Binda, O.; Juillard, F.; Ducassou, J.N.; Kleijwegt, C.; Paris, G.; Didillon, A.; Baklouti, F.; Corpet, A.; Couté, Y.; Côté, J.; Lomonte, P. SMA-linked SMN mutants prevent phase separation properties and SMN interactions with FMRP family members. Life Science Alliance, 2023, 6(1), e202201429. doi: 10.26508/lsa.202201429
  16. Krause, K. D.; Rees, K.; Algar, W. R. Assessing the Steric Impact of Surface Ligands on the Proteolytic Turnover of Quantum Dot–Peptide Conjugates. ACS Appl. Mater. Interfaces, 2023, 15(49), 57799–57811. doi: 10.1021/acsami.3c12665
  17. Fedorova, N.; Sokolov, A.; Trashkov, A.; Varfolomeeva, E. The preparation of samples for studying neutrophils without their isolation. Biological Communications, 2023, 68(3), 145-150. doi: 10.21638/spbu03.2023.302
  18. Khadria, A.; Paavola, C.D.; Maslov, K.; Brown-Augsburger, P.L.; Grealish, P.F.; Lozano, E.; Blankenship, R.L.; Cao, R.; Shi, J.; Beals, J.M.; Oladipupo, S.S.; Wang, L.V. Photoacoustic imaging of the dynamics of a dye-labeled IgG4 monoclonal antibody in subcutaneous tissue reveals a transient decrease in murine blood oxygenation under anesthesia. Journal of Biomedical Optics, 2023, 28(11), 116002. doi: 10.1117/1.jbo.28.11.116002
  19. Kicková, E.; Sadeghi, A.; Puranen, J.; Tavakoli, S.; Sen, M.; Ranta, V.-P.; Arango-Gonzalez, B.; Bolz, S.; Ueffing, M.; Salmaso, S.; Caliceti, P.; Toropainen, E.; Ruponen, M.; Urtti, A. Pharmacokinetics of Pullulan–Dexamethasone Conjugates in Retinal Drug Delivery. Pharmaceutics, 2023, 14(1), 12. doi: 10.3390/pharmaceutics14010012
  20. Agnello, L.; Tortorella, S.; d’Argenio, A.; Carbone, C.; Camorani, S.; Locatelli, E.; Auletta, L.; Sorrentino, D.; Fedele, M.; Zannetti, A.; Franchini, M.C.; Cerchia, L. Optimizing cisplatin delivery to triple-negative breast cancer through novel EGFR aptamer-conjugated polymeric nanovectors. Journal of Experimental & Clinical Cancer Research : CR, 2023, 40, 239. doi: 10.1186/s13046-021-02039-w
  21. Yamada, T.; Ishimaru, M.; Shoji, T.; Tomiyasu, H.; Tochinai, R.; Taguchi, K.; Komatsu, T. Polyoxazoline-Conjugated l-Asparaginase: An Antibody-Production-Free Therapeutic Agent for Acute Lymphoblastic Leukemia. ACS Appl. Bio Mater., 2023, 6(12), 5789–5797. doi: 10.1021/acsabm.3c00888
  22. Carias, A.M.; Schneider, J.R.; Madden, P.; Lorenzo-Redondo, R.; Araínga, M.; Pegu, A.; Cianci, G.C.; Maric, D.; Villinger, F.; Mascola, J.R.; Veazey, R.S.; Hope, T.J. Anatomic distribution of intravenous injected IgG takes approximately 1 week to achieve stratum corneum saturation in vaginal tissues. The Journal of Immunology, 2023, 207(2), 505-511. doi: 10.4049/jimmunol.2100253
  23. Landy, M.A.; Goyal, M.; Casey, K.M.; Liu, C.; Lai, H.C. Loss of Prdm12 during development, but not in mature nociceptors, causes defects in pain sensation. Cell reports, 2023, 34(13), 108913. doi: 10.1016/j.celrep.2021.108913
  24. Wang, L.; Qiao, S.; Xia, R.; Liu, Y.; Hu, Y.; Wu, Y.; Zhou, J.; Liang, G.; Tian, T.; Cao, L. Mesenchymal Stromal Cell–Derived Magnetic Nanovesicles for Enhanced Skin Retention and Hair Follicle Growth. Cytotherapy, 2023, 25(11), 1176-1185. doi: 10.1016/j.jcyt.2023.07.001
  25. Kerr, M. D.; McBride, D. A.; Johnson, W. T.; Chumber, A. K.; Najibi, A. J.; Seo, B. R.; Stafford, A. G.; Scadden, D. T.; Mooney, D. J.; Shah, N. J. Immune-Responsive Biodegradable Scaffolds for Enhancing Neutrophil Regeneration. Bioengineering & Translational Medicine, 2023, 8(1), e10309. doi: 10.1002/btm2.10309
  26. Toti, K. S.; Campbell, R. G.; Lee, H.; Salmaso, V.; Suresh, R. R.; Gao, Z.-G.; Jacobson, K. A. Fluorescent A2A and A3 Adenosine Receptor Antagonists as Flow Cytometry Probes. Purinergic Signalling, 2023, 19(3), 565–578. doi: 10.1007/s11302-022-09873-3
  27. Shesterikova, E. M.; Bondarenko, V. S.; Volkova, P. Yu. Differential Gene Expression in Chronically Irradiated Herbaceous Species from the Chernobyl Exclusion Zone. International Journal of Radiation Biology, 2023, 99(2), 229–237. doi: 10.1080/09553002.2022.2087927
  28. Gabold, B.; Adams, F.; Brameyer, S.; Jung, K.; Ried, C. L.; Merdan, T.; Merkel, O. M. Transferrin-Modified Chitosan Nanoparticles for Targeted Nose-to-Brain Delivery of Proteins. Drug Deliv. and Transl. Res., 2023, 13(3), 822–838. doi: 10.1007/s13346-022-01245-z
  29. Bär, S. I.; Schleser, S. W.; Oberhuber, N.; Herrmann, A.; Schlotte, L.; Weber, S. E.; Schobert, R. Trans-[Bis(Benzimidazol-2-Ylidene)Dichlorido]Platinum(II) Complexes with Peculiar Modes of Action and Activity against Cisplatin-Resistant Cancer Cells. Journal of Inorganic Biochemistry, 2023, 238, 112028. doi: 10.1016/j.jinorgbio.2022.112028
  30. Loukas, I.; Simeoni, F.; Milan, M.; Inglese, P.; Patel, H.; Goldstone, R.; East, P.; Strohbuecker, S.; Mitter, R.; Talsania, B.; Tang, W.; Ratcliffe, C. D. H.; Sahai, E.; Shahrezaei, V.; Scaffidi, P. Selective Advantage of Epigenetically Disrupted Cancer Cells via Phenotypic Inertia. Cancer Cell, 2023, 41(1), 70-87.e14. doi: 10.1016/j.ccell.2022.10.002
  31. Repellin, M.; Carton, F.; Boschi, F.; Galiè, M.; Perduca, M.; Calderan, L.; Jacquier, A.; Carras, J.; Schaeffer, L.; Briançon, S.; Lollo, G.; Malatesta, M. Repurposing Pentamidine Using Hyaluronic Acid-Based Nanocarriers for Skeletal Muscle Treatment in Myotonic Dystrophy. Nanomedicine: Nanotechnology, Biology and Medicine, 2023, 47, 102623. doi: 10.1016/j.nano.2022.102623
  32. Pershina, A. G.; Demin, A. M.; Perekucha, N. A.; Brikunova, O. Y.; Efimova, L. V.; Nevskaya, K. V.; Vakhrushev, A. V.; Zgoda, V. G.; Uimin, M. A.; Minin, A. S.; Malkeyeva, D.; Kiseleva, E.; Zima, A. P.; Krasnov, V. P.; Ogorodova, L. M. Peptide Ligands on the PEGylated Nanoparticle Surface and Human Serum Composition Are Key Factors for the Interaction between Immune Cells and Nanoparticles. Colloids and Surfaces B: Biointerfaces, 2023, 221, 112981. doi: 10.1016/j.colsurfb.2022.112981
  33. Nie, Q.; Li, C.; Wang, Y.; Hu, Y.; Pu, W.; Zhang, Q.; Cai, J.; Lin, Y.; Li, G.; Wang, C.; Li, L.; Dou, Y.; Zhang, J. Pathologically Triggered in Situ Aggregation of Nanoparticles for Inflammation-Targeting Amplification and Therapeutic Potentiation. Acta Pharmaceutica Sinica B, 2023, 13(1), 390–409. doi: 10.1016/j.apsb.2022.07.013
  34. Hebels, E. R.; Bindt, F.; Walther, J.; van Geijn, M.; Weterings, J.; Hu, Q.; Colombo, C.; Liskamp, R.; Rijcken, C.; Hennink, W. E.; Vermonden, T. Orthogonal Covalent Entrapment of Cargo into Biodegradable Polymeric Micelles via Native Chemical Ligation. Biomacromolecules, 2023, 24(10), 4385–4396. doi: 10.1021/acs.biomac.2c00865
  35. Robertson, N.; Sempere, L.; Kenyon, E.; Mallet, C.; Smith, K.; Hix, J.; Halim, A.; Fan, J.; Moore, A. Omniparticle Contrast Agent for Multimodal Imaging: Synthesis and Characterization in an Animal Model. Mol Imaging Biol, 2023, 25(2), 401–412. doi: 10.1007/s11307-022-01770-w
  36. Chen, L.; Xu, N.; Wang, P.; Zhu, H.; Zhang, Z.; Yang, Z.; Zhang, W.; Guo, H.; Lin, J. Nanoalbumin–Prodrug Conjugates Prepared via a Thiolation-and-Conjugation Method Improve Cancer Chemotherapy and Immune Checkpoint Blockade Therapy by Promoting CD8+ T-Cell Infiltration. Bioengineering & Translational Medicine, 2023, 8(1), e10377. doi: 10.1002/btm2.10377
  37. Sokolov, A. V.; Isakova-Sivak, I. N.; Mezhenskaya, D. A.; Kostevich, V. A.; Gorbunov, N. P.; Elizarova, A. Yu.; Matyushenko, V. A.; Berson, Yu. M.; Grudinina, N. A.; Kolmakov, N. N.; Zabrodskaya, Y. A.; Komlev, A. S.; Semak, I. V.; Budevich, A. I.; Rudenko, L. G.; Vasilyev, V. B. Molecular Mimicry of the Receptor-Binding Domain of the SARS-CoV-2 Spike Protein: From the Interaction of Spike-Specific Antibodies with Transferrin and Lactoferrin to the Antiviral Effects of Human Recombinant Lactoferrin. Biometals, 2023, 36(3), 437–462. doi: 10.1007/s10534-022-00458-6
  38. Strada, A.; Frigerio, R.; Bergamaschi, G.; Gagni, P.; Cretich, M.; Gori, A. Membrane-Sensing Peptides for Extracellular Vesicle Analysis. Peptide Microarrays: Methods and Protocols, 2023, 249–257. doi: 10.1007/978-1-0716-2732-7_18
  39. Li, H.; Zhong, Y.; Wang, S.; Zha, M.; Gu, W.; Liu, G.; Wang, B.; Yu, Z.; Wang, Y.; Li, K.; Yin, Y.; Mu, J.; Chen, X. In Vivo Bioorthogonal Labeling of Rare-Earth Doped Nanoparticles for Improved NIR-II Tumor Imaging by Extracellular Vesicle-Mediated Targeting. Nano Res., 2023, 16(2), 2895–2904. doi: 10.1007/s12274-022-5033-8
  40. Husser, C.; Baudrey, S.; Ryckelynck, M. High-Throughput Development and Optimization of RNA-Based Fluorogenic Biosensors of Small Molecules Using Droplet-Based Microfluidics. Nucleic Acid Aptamers. Methods in Molecular Biology, 2023, 2570, 243–269. doi: 10.1007/978-1-0716-2695-5_19
  41. Adachi, J.; Oda, H.; Fukushima, T.; Lestari, B.; Kimura, H.; Sugai, H.; Shiraki, K.; Hamaguchi, R.; Sato, K.; Kinbara, K. Dense and Acidic Organelle-Targeted Visualization in Living Cells: Application of Viscosity-Responsive Fluorescence Utilizing Restricted Access to Minimum Energy Conical Intersection. Anal. Chem., 2023, 95(12), 5196–5204. doi: 10.1021/acs.analchem.2c04133
  42. Cadavid, J. L.; Latour, S.; Nowlan, F.; Co, I. L.; Landon-Brace, N.; Wouters, B. G.; Grünwald, B. T.; Nitz, M.; Jackson, H. W.; McGuigan, A. P. An Engineered Paper-Based 3D Coculture Model of Pancreatic Cancer to Study the Impact of Tissue Architecture and Microenvironmental Gradients on Cell Phenotype. Advanced Healthcare Materials, 2023, 12(14), 2201846. doi: 10.1002/adhm.202201846
  43. Ko, H. S.; Yang, D. H.; Kim, A.; Wie, J. H.; Kim, S. H.; Jeong, G.-J.; Hyun, H.; Shin, J. C.; Chun, H. J. Visible Light-Curable Methacrylated Glycol Chitosan Hydrogel Patches for Prenatal Closure of Fetal Myelomeningocele. Carbohydrate Polymers, 2023, 311, 120620. doi: 10.1016/j.carbpol.2023.120620
  44. Babi, M.; Williams, A.; Reid, M.; Grandfield, K.; Bassim, N. D.; Moran-Mirabal, J. M. Unraveling the Supramolecular Structure and Nanoscale Dislocations of Bacterial Cellulose Ribbons Using Correlative Super-Resolution Light and Electron Microscopy. Biomacromolecules, 2023, 24(1), 258–268. doi: 10.1021/acs.biomac.2c01108
  45. Khrustaleva, L.; Nzeha, M.; Ermolaev, A.; Nikitina, E.; Romanov, V. Two-Step Identification of N-, S-, R- and T-Cytoplasm Types in Onion Breeding Lines Using High-Resolution Melting (HRM)-Based Markers. International Journal of Molecular Sciences, 2023, 24(2), 1605. doi: 10.3390/ijms24021605
  46. Zhang, B.; Pan, H.; Chen, Z.; Yin, T.; Zheng, M.; Cai, L. Twin-Bioengine Self-Adaptive Micro/Nanorobots Using Enzyme Actuation and Macrophage Relay for Gastrointestinal Inflammation Therapy. Sci. Adv., 2023, 9(8), eadc8978. doi: 10.1126/sciadv.adc8978
  47. Uvyn, A.; Tonneaux, C.; Fossépré, M.; Ouvrier-Buffet, A.; De Geest, B. G.; Surin, M. Towards a Rational Design of Antibody-Recruiting Molecules through a Computational Microscopy View of Their Interactions with the Target Antibody. Chemistry – A European Journal, 2023, 29(30), e202300474. doi: 10.1002/chem.202300474
  48. McGregor, L. A.; Zhu, B.; Goetz, A. M.; Sczepanski, J. T. Thymine DNA Glycosylase Is an RNA-Binding Protein with High Selectivity for G-Rich Sequences. Journal of Biological Chemistry, 2023, 299(4), 104590. doi: 10.1016/j.jbc.2023.104590
  49. Li, W.; Liu, Z.; Wang, P.; Di, R.; Wang, X.; Liu, Y.; Chu, M. The Transcription Factor RUNX1 Affects the Maturation of Porcine Oocytes via the BMP15/TGF-β Signaling Pathway. International Journal of Biological Macromolecules, 2023, 238, 124026. doi: 10.1016/j.ijbiomac.2023.124026
  50. Shushunova, N. A.; Mayorova, O. A.; Prikhozhdenko, E. S.; Goryacheva, O. A.; Kulikov, O. A.; Plastun, V. O.; Gusliakova, O. I.; Muslimov, A. R.; Inozemtseva, O. A.; Pyataev, N. A.; Shirokov, A. A.; Gorin, D. A.; Sukhorukov, G. B.; Sindeeva, O. A. Targeted Therapy for Glomerulonephritis Using Arterial Delivery of Encapsulated Etanercept. International Journal of Molecular Sciences, 2023, 24(3), 2784. doi: 10.3390/ijms24032784
  51. Yodsanit, N.; Shirasu, T.; Huang, Y.; Yin, L.; Islam, Z. H.; Gregg, A. C.; Riccio, A. M.; Tang, R.; Kent, E. W.; Wang, Y.; Xie, R.; Zhao, Y.; Ye, M.; Zhu, J.; Huang, Y.; Hoyt, N.; Zhang, M.; Hossack, J. A.; Salmon, M.; Kent, K. C.; Guo, L.-W.; Gong, S.; Wang, B. Targeted PERK Inhibition with Biomimetic Nanoclusters Confers Preventative and Interventional Benefits to Elastase-Induced Abdominal Aortic Aneurysms. Bioactive Materials, 2023, 26, 52–63. doi: 10.1016/j.bioactmat.2023.02.009
  52. Bariana, M.; Zhang, B.; Sun, J.; Wang, W.; Wang, J.; Cassella, E.; Myint, F.; Anuncio, S. A.; Ouk, S.; Liou, H.-C.; Tan, M.; Wang, H.; Zakrzewski, J. L. Targeted Lymphoma Therapy Using a Gold Nanoframework-Based Drug Delivery System. ACS Appl. Mater. Interfaces, 2023, 15(5), 6312–6325. doi: 10.1021/acsami.2c17214
  53. Lee, J.-R.; Sim, W.-S.; Park, H.-J.; Park, B.-W.; Joung, Y. K. Targeted Delivery of Apoptotic Cell-Derived Nanovesicles Prevents Cardiac Remodeling and Attenuates Cardiac Function Exacerbation. Advanced Functional Materials, 2023, 33(23), 2210864. doi: 10.1002/adfm.202210864
  54. Bashore, C.; Prakash, S.; Johnson, M. C.; Conrad, R. J.; Kekessie, I. A.; Scales, S. J.; Ishisoko, N.; Kleinheinz, T.; Liu, P. S.; Popovych, N.; Wecksler, A. T.; Zhou, L.; Tam, C.; Zilberleyb, I.; Srinivasan, R.; Blake, R. A.; Song, A.; Staben, S. T.; Zhang, Y.; Arnott, D.; Fairbrother, W. J.; Foster, S. A.; Wertz, I. E.; Ciferri, C.; Dueber, E. C. Targeted Degradation via Direct 26S Proteasome Recruitment. Nature Chemical Biology, 2023, 19(1), 55–63. doi: 10.1038/s41589-022-01218-w
  55. Zashikhina, N.; Gladnev, S.; Sharoyko, V.; Korzhikov-Vlakh, V.; Korzhikova-Vlakh, E.; Tennikova, T. Synthesis and Characterization of Nanoparticle-Based Dexamethasone-Polypeptide Conjugates as Potential Intravitreal Delivery Systems. International Journal of Molecular Sciences, 2023, 24(4), 3702. doi: 10.3390/ijms24043702
  56. Anderson, C. F.; Wang, Q.; Stern, D.; Leonard, E. K.; Sun, B.; Fergie, K. J.; Choi, C.; Spangler, J. B.; Villano, J.; Pekosz, A.; Brayton, C. F.; Jia, H.; Cui, H. Supramolecular Filaments for Concurrent ACE2 Docking and Enzymatic Activity Silencing Enable Coronavirus Capture and Infection Prevention. Matter, 2023, 6(2), 583–604. doi: 10.1016/j.matt.2022.11.027
  57. Reddi, R. N.; Rogel, A.; Gabizon, R.; Rawale, D. G.; Harish, B.; Marom, S.; Tivon, B.; Arbel, Y. S.; Gurwicz, N.; Oren, R.; David, K.; Liu, J.; Duberstein, S.; Itkin, M.; Malitsky, S.; Barr, H.; Katz, B.-Z.; Herishanu, Y.; Shachar, I.; Shulman, Z.; London, N. Sulfamate Acetamides as Self-Immolative Electrophiles for Covalent Ligand-Directed Release Chemistry. J. Am. Chem. Soc, 2023, 145(6), 3346–3360. doi: 10.1021/jacs.2c08853
  58. Marin, M. A.; Gleichman, A. J.; Brumm, A. J.; Carmichael, S. T. Subcortical White Matter Stroke in the Mouse: Inducing Injury and Tracking Cellular Proliferation. Neural Repair: Methods and Protocols, 2023, 2616, 13–20. doi: 10.1007/978-1-0716-2926-0_2
  59. Chhonker, Y. S.; Wojtynek, N. E.; Agrawal, P.; Mohs, A. M.; Murry, D. J. A Simple and Sensitive LC-MS/MS for Quantitation of ICG in Rat Plasma: Application to a Pre-Clinical Pharmacokinetic Study. Separations, 2023, 10(2), 66. doi: 10.3390/separations10020066
  60. Mao, X.; Ye, R. One-Pot Synthesis of Enzyme and Antibody/CaHPO4 Nanoflowers for Magnetic Chemiluminescence Immunoassay of Salmonella Enteritidis. Sensors, 2023, 23(5), 2779. doi: 10.3390/s23052779
  61. Psotta, C.; Chaturvedi, V.; Gonzalez-Martinez, J. F.; Sotres, J.; Falk, M. Portable Prussian Blue-Based Sensor for Bacterial Detection in Urine. Sensors, 2023, 23(1), 388. doi: 10.3390/s23010388
  62. Gerasimova, N. S.; Pestov, N. A.; Studitsky, V. M. Role of Histone Tails and Single Strand DNA Breaks in Nucleosomal Arrest of RNA Polymerase. International Journal of Molecular Sciences, 2023, 24(3), 2295. doi: 10.3390/ijms24032295
  63. Lai, C.; Zhang, B.; Li, D.; Tan, X.; Luo, B.; Shen, J.; Li, L.; Shao, J. Rational Design of a Minimum Nanoplatform for Maximizing Therapeutic Potency: Three Birds with One Stone. Journal of Colloid and Interface Science, 2023, 635, 441–455. doi: 10.1016/j.jcis.2022.12.157
  64. Sharma, A. K.; Fitieh, A. M.; Locke, A. J.; Ali, J. Y. H.; Ismail, I. H. Quantification of Protein Enrichment at Site-Specific DNA Double-Strand Breaks by Chromatin Immunoprecipitation in Cultured Human Cells. STAR Protocols, 2023, 4(1), 101917. doi: 10.1016/j.xpro.2022.101917
  65. Liu, Y.; Jia, Z.; Ma, L.; Wang, D. Pyrophosphorylated-Cholesterol-Modified Bone-Targeting Liposome Formulation Procedure. Liposomes: Methods and Protocols, 2023, 2622, 207–220. doi: 10.1007/978-1-0716-2954-3_18
  66. Cui, J.; Zhang, C.; Liu, H.; Yang, L.; Liu, X.; Zhang, J.; Zhou, Y.; Zhang, J.; Yan, X. Pulmonary Delivery of Recombinant Human Bleomycin Hydrolase Using Mannose-Modified Hierarchically Porous UiO-66 for Preventing Bleomycin-Induced Pulmonary Fibrosis. ACS Appl. Mater. Interfaces, 2023, 15(9), 11520–11535. doi: 10.1021/acsami.2c20479
  67. Wlodarczyk, M. T.; Dragulska, S. A.; Chen, Y.; Poursharifi, M.; Acosta Santiago, M.; Martignetti, J. A.; Mieszawska, A. J. Pt(II)-PLGA Hybrid in a PH-Responsive Nanoparticle System Targeting Ovarian Cancer. Pharmaceutics, 2023, 15(2), 607. doi: 10.3390/pharmaceutics15020607
  68. Sabuncu, S.; Montoya Mira, J.; Quentel, A.; Gomes, M. M.; Civitci, F.; Fischer, J. M.; Yildirim, A. Protein-Coated Biodegradable Gas-Stabilizing Nanoparticles for Cancer Therapy and Diagnosis Using Focused Ultrasound. Advanced Materials Interfaces, 2023, 10(2), 2201543. doi: 10.1002/admi.202201543
  69. Dhara, S. P.; Udvadia, A. J. Profiling Dynamic Changes in DNA Accessibility During Axon Regeneration After Optic Nerve Crush in Adult Zebrafish. Axon Regeneration: Methods and Protocols, 2023, 2636, 323–341. doi: 10.1007/978-1-0716-3012-9_18
  70. Pizzi, D.; Humphries, J.; Morrow, J. P.; Mahmoud, A. M.; Fletcher, N. L.; Sonderegger, S. E.; Bell, C. A.; Thurecht, K. J.; Kempe, K. Probing the Biocompatibility and Immune Cell Association of Chiral, Water-Soluble, Bottlebrush Poly(2-Oxazoline)s. Biomacromolecules, 2023, 24(1), 246–257. doi: 10.1021/acs.biomac.2c01105
  71. Barclay, M. S.; Chowdhury, A. U.; Biaggne, A.; Huff, J. S.; Wright, N. D.; Davis, P. H.; Li, L.; Knowlton, W. B.; Yurke, B.; Pensack, R. D.; Turner, D. B. Probing DNA Structural Heterogeneity by Identifying Conformational Subensembles of a Bicovalently Bound Cyanine Dye. The Journal of Chemical Physics, 2023, 158(3), 035101. doi: 10.1063/5.0131795
  72. Ruan, Z.; Li, S.; Grigoropoulos, A.; Amiri, H.; Hilburg, S. L.; Chen, H.; Jayapurna, I.; Jiang, T.; Gu, Z.; Alexander-Katz, A.; Bustamante, C.; Huang, H.; Xu, T. Population-Based Heteropolymer Design to Mimic Protein Mixtures. Nature, 2023, 615(7951), 251–258. doi: 10.1038/s41586-022-05675-0
  73. Guo, H.; Xu, W.; Nomoto, T.; Kanamori, K.; Voon, Y. M.; Honda, Y.; Yamada, N.; Takemoto, H.; Matsui, M.; Nishiyama, N. Polymeric Ligands Comprising Sulfur-Containing Amino Acids for Targeting Tumor-Associated Amino Acid Transporters. Biomaterials, 2023, 293, 121987. doi: 10.1016/j.biomaterials.2022.121987
  74. Song, Y.; He, Y.; Rong, L.; Wang, Z.; Ma, Y.; Zhang, N.; Wang, B. “Platelet-Coated Bullets” Biomimetic Nanoparticles to Ameliorate Experimental Colitis by Targeting Endothelial Cells. Biomaterials Advances, 2023, 148, 213378. doi: 10.1016/j.bioadv.2023.213378
  75. Meiers, J.; Dastbaz, J.; Adam, S.; Rasheed, S.; Kirsch, S. H.; Meiser, P.; Gross, P.; Müller, R.; Titz, A. Pineapple Lectin AcmJRL Binds SARS-CoV-2 Spike Protein in a Carbohydrate-Dependent Fashion**. ChemBioChem, 2023, 24(3), e202200463. doi: 10.1002/cbic.202200463
  76. Nizamov, T. R.; Iliasov, A. R.; Vodopyanov, S. S.; Kozhina, I. V.; Bordyuzhin, I. G.; Zhukov, D. G.; Ivanova, A. V.; Permyakova, E. S.; Mogilnikov, P. S.; Vishnevskiy, D. A.; Shchetinin, I. V.; Abakumov, M. A.; Savchenko, A. G. Study of Cytotoxicity and Internalization of Redox-Responsive Iron Oxide Nanoparticles on PC-3 and 4T1 Cancer Cell Lines. Pharmaceutics, 2023, 15(1), 127. doi: 10.3390/pharmaceutics15010127
  77. Roussel, S.; Grenier, P.; Chénard, V.; Bertrand, N. Dual-Labelled Nanoparticles Inform on the Stability of Fluorescent Labels In Vivo. Pharmaceutics 2023, 15 (3), 769., 2023, 15(3), 769. doi: 10.3390/pharmaceutics15030769
  78. Khramtsov, Y. V.; Ulasov, A. V.; Rosenkranz, A. A.; Slastnikova, T. A.; Lupanova, T. N.; Georgiev, G. P.; Sobolev, A. S. An Approach to Evaluate the Effective Cytoplasmic Concentration of Bioactive Agents Interacting with a Selected Intracellular Target Protein. Pharmaceutics, 2023, 15(2), v. doi: 10.3390/pharmaceutics15020324
  79. Asker, M.; Krieger, J.-P.; Liles, A.; Tinsley, I. C.; Borner, T.; Maric, I.; Doebley, S.; Furst, C. D.; Börchers, S.; Longo, F.; Bhat, Y. R.; De Jonghe, B. C.; Hayes, M. R.; Doyle, R. P.; Skibicka, K. P. Peripherally Restricted Oxytocin Is Sufficient to Reduce Food Intake and Motivation, While CNS Entry Is Required for Locomotor and Taste Avoidance Effects. Diabetes, Obesity and Metabolism, 2023, 25(3), 856–877. doi: 10.1111/dom.14937
  80. Meng, P.; Shao, Y.; Xiong, Y.; Zhang, L.; Bao, H.; Lu, H. Peptide- and Protein-Level Combined Strategy for Analyzing Newly Synthesized Proteins by Integrating Tandem Orthogonal Proteolysis with Cleavable Bioorthogonal Tagging. Anal. Chem., 2023, 95(2), 628–637. doi: 10.1021/acs.analchem.2c01537
  81. Nikitin, M. P. Non-Complementary Strand Commutation as a Fundamental Alternative for Information Processing by DNA and Gene Regulation. Nature Chemistry, 2023, 15(1), 70-82. doi: 10.1038/s41557-022-01111-y
  82. Song, Q.-X.; Liu, N.-N.; Liu, Z.-X.; Zhang, Y.-Z.; Rety, S.; Hou, X.-M.; Xi, X.-G. Nonstructural N- and C-Tails of Dbp2 Confer the Protein Full Helicase Activities. Journal of Biological Chemistry, 2023, 299(5), 104592. doi: 10.1016/j.jbc.2023.104592
  83. Garafutdinov, R. R.; Burkhanova, G. F.; Maksimov, I. V.; Sakhabutdinova, A. R. New Method for MicroRNA Detection Based on Multimerization. Analytical Biochemistry, 2023, 664, 115049. doi: 10.1016/j.ab.2023.115049
  84. Cai, J.; Liu, L.; Qin, Z.; Liu, S.; Wang, Y.; Chen, Z.; Yao, Y.; Zheng, L.; Zhao, J.; Gao, M. Natural Morin-Based Metal Organic Framework Nanoenzymes Modulate Articular Cavity Microenvironment to Alleviate Osteoarthritis. Research, 2023, 6, 0068. doi: 10.34133/research.0068
  85. Liu, B.; Kong, Y.; Alimi, O. A.; Kuss, M. A.; Tu, H.; Hu, W.; Rafay, A.; Vikas, K.; Shi, W.; Lerner, M.; Berry, W. L.; Li, Y.; Carlson, M. A.; Duan, B. Multifunctional Microgel-Based Cream Hydrogels for Postoperative Abdominal Adhesion Prevention. ACS Nano, 2023, 17(4), 3847–3864. doi: 10.1021/acsnano.2c12104
  86. Mitin, D. E.; Chubarov, A. S. Fluorinated Human Serum Albumin as Potential 19F Magnetic Resonance Imaging Probe. Molecules, 2023, 28(4), 1695. doi: 10.3390/molecules28041695.
  87. Kropacheva, N. O.; Golyshkin, A. A.; Vorobyeva, M. A.; Meschaninova, M. I. Convenient Solid-Phase Attachment of Small-Molecule Ligands to Oligonucleotides via a Biodegradable Acid-Labile P-N-Bond. Molecules, 2023, 28(4), 1904. doi: 10.3390/molecules28041904
  88. Sapozhnikova, K. A.; Gulyak, E. L.; Misyurin, V. A.; Simonova, M. A.; Ryabukhina, E. V.; Alexeeva, A. V.; Tikhonova, N. A.; Lyzhko, N. A.; Popova, G. P.; Misyurin, A. V.; Ustinov, A. V.; Korshun, V. A.; Alferova, V. A.; Ryazantsev, D. Y.; Brylev, V. A. Branched Linkers for Site-Specific Fluorescent Labeling of Antibodies. Molecules, 2023, 28(1), 425. doi: 10.3390/molecules28010425
  89. Pattadar, D.; Zheng, L.; Robb, A. J.; Beery, D.; Yang, W.; Hanson, K.; Saavedra, S. S. Molecular Orientation of −PO3H2 and −COOH Functionalized Dyes on TiO2, Al2O3, ZrO2, and ITO: A Comparative Study. J. Phys. Chem. C, 2023, 127(5), 2705–2715. doi: 10.1021/acs.jpcc.2c08632
  90. Rybkin, I.; Pinyaev, S.; Sindeeva, O.; German, S. V.; Koblar, M.; Pyataev, N.; Čeh, M.; Gorin, D.; Sukhorukov, G.; Lapanje, A. Modification of Bacterial Cells for in Vivo Remotely Guided Systems. Frontiers in Bioengineering and Biotechnology, 2023, 10, 1070851. doi: 10.3389/fbioe.2022.1070851
  91. Dong, B.; Qiu, Y.; Liu, Z.; Huang, J.; Wang, Z.; Tu, Q.; Zhou, Z.; He, J.; Wang, Y.; Liu, X.; Zhang, J.; Shuai, X.; Tao, J.; Xia, W. Manipulating Bioactivities of Endothelial Progenitor Cell-Derived Exosomes for Promoting Angiogenesis in Ischemic Vascular Diseases. Nano Today, 2023, 48, 101758. doi: 10.1016/j.nantod.2023.101758
  92. Loppinet, E.; Besser, H. A.; Sewa, A. S.; Yang, F.-C.; Jabri, B.; Khosla, C. LRP-1 Links Post-Translational Modifications to Efficient Presentation of Celiac Disease-Specific T Cell Antigens. Cell Chemical Biology, 2023, 30(1), 55-68.e10. doi: 10.1016/j.chembiol.2022.12.002
  93. Zeng, Z.; Hou, W.; Hu, Z.; Liu, L.; Liu, Z.; Shi, Y.; Li, M.; Chen, Y. Long-Acting Insulin-Zwitterionic Polymer Conjugate Mitigates Hypoglycemia. Chemistry – A European Journal, 2023, 29(12), e202203460. doi: 10.1002/chem.202203460
  94. Liao, T.-W.; Huang, L.; Wilson, T. J.; Ganser, L. R.; Lilley, D. M. J.; Ha, T. Linking Folding Dynamics and Function of SAM/SAH Riboswitches at the Single Molecule Level. Nucleic Acids Research, 2023, 51(17), 8957–8969. doi: 10.1093/nar/gkad633
  95. Barberio, A. E.; Smith, S. G.; Pires, I. S.; Iyer, S.; Reinhardt, F.; Melo, M. B.; Suh, H.; Weinberg, R. A.; Irvine, D. J.; Hammond, P. T. Layer-by-Layer Interleukin-12 Nanoparticles Drive a Safe and Effective Response in Ovarian Tumors. Bioengineering & Translational Medicine, 2023, 8(2), e10453. doi: 10.1002/btm2.10453
  96. Janiszewski, T.; Kołt, S.; Ciastoń, I.; Vizovisek, M.; Poręba, M.; Turk, B.; Drąg, M.; Kozieł, J.; Kasperkiewicz, P. Investigation of Osteoclast Cathepsin K Activity in Osteoclastogenesis and Bone Loss Using a Set of Chemical Reagents. Cell Chemical Biology, 2023, 30(2), 159-174.e8. doi: 10.1016/j.chembiol.2023.01.001
  97. Bao, X.; Qian, K.; Xu, M.; Chen, Y.; Wang, H.; Pan, T.; Wang, Z.; Yao, P.; Lin, L. Intestinal Epithelium Penetration of Liraglutide via Cholic Acid Pre-Complexation and Zein/Rhamnolipids Nanocomposite Delivery. Journal of Nanobiotechnology, 2023, 21(1), 16. doi: 10.1186/s12951-022-01743-9
  98. Son, S.; Nam, J.; Kim, A. S.; Ahn, J.; Park, K. S.; Phoo, M. T.; Sherren, B.; Zou, W.; Lee, S.-H.; Farokhzad, O. C.; Shi, J.; Moon, J. J. Induction of T-Helper-17-Cell-Mediated Anti-Tumour Immunity by Pathogen-Mimicking Polymer Nanoparticles. Nature Biomedical Engineering, 2023, 7(1), 72–84. doi: 10.1038/s41551-022-00973-4
  99. Cho, H.; Jeon, S. I.; Shim, M. K.; Ahn, C.-H.; Kim, K. In Situ Albumin-Binding and Esterase-Specifically Cleaved BRD4-Degrading PROTAC for Targeted Cancer Therapy. Biomaterials, 2023, 295, 122038. doi: 10.1016/j.biomaterials.2023.122038
  100. Pizarek, J. A.; Fischer, N. G.; Aparicio, C. Immunomodulatory IL-23 Receptor Antagonist Peptide Nanocoatings for Implant Soft Tissue Healing. Dental Materials, 2023, 39(2), 204–216. doi: 10.1016/j.dental.2023.01.001
  101. Wang, Y.-J.; Li, L.; Yu, J.; Hu, H.-Y.; Liu, Z.-X.; Jiang, W.-J.; Xu, W.; Guo, X.-P.; Wang, F.-S.; Sheng, J.-Z. Imaging of Escherichia Coli K5 and Glycosaminoglycan Precursors via Targeted Metabolic Labeling of Capsular Polysaccharides in Bacteria. Sci. Adv., 2023, 9(7), eade4770. doi: 10.1126/sciadv.ade4770
  102. Kalinovsky, D. V.; Kholodenko, I. V.; Kibardin, A. V.; Doronin, I. I.; Svirshchevskaya, E. V.; Ryazantsev, D. Y.; Konovalova, M. V.; Rozov, F. N.; Larin, S. S.; Deyev, S. M.; Kholodenko, R. V. Minibody-Based and ScFv-Based Antibody Fragment-Drug Conjugates Selectively Eliminate GD2-Positive Tumor Cells. International Journal of Molecular Sciences, 2023, 24(2), 1239. doi: 10.3390/ijms24021239
  103. Malinovskaya, J.; Salami, R.; Valikhov, M.; Vadekhina, V.; Semyonkin, A.; Semkina, A.; Abakumov, M.; Harel, Y.; Levy, E.; Levin, T.; Persky, R.; Chekhonin, V.; Lellouche, J.-P.; Melnikov, P.; Gelperina, S. Supermagnetic Human Serum Albumin (HSA) Nanoparticles and PLGA-Based Doxorubicin Nanoformulation: A Duet for Selective Nanotherapy. International Journal of Molecular Sciences, 2023, 24(1), 627. doi: 10.3390/ijms24010627
  104. Drozdov, A. S.; Komarova, K. S.; Mochalova, E. N.; Komedchikova, E. N.; Shipunova, V. O.; Nikitin, M. P. Fluorescent Magnetic Nanoparticles for Bioimaging through Biomimetic Surface Modification. International Journal of Molecular Sciences, 2023, 24(1), 134. doi: 10.3390/ijms24010134
  105. Miltner, N.; Kalló, G.; Csősz, É.; Miczi, M.; Nagy, T.; Mahdi, M.; Mótyán, J. A.; Tőzsér, J. Identification of SARS-CoV-2 Main Protease (Mpro) Cleavage Sites Using Two-Dimensional Electrophoresis and In Silico Cleavage Site Prediction. International Journal of Molecular Sciences, 2023, 24(4), 3236. doi: 10.3390/ijms24043236
  106. Sandberg, E.; Piguet, J.; Liu, H.; Widengren, J. Combined Fluorescence Fluctuation and Spectrofluorometric Measurements Reveal a Red-Shifted, Near-IR Emissive Photo-Isomerized Form of Cyanine 5. International Journal of Molecular Sciences, 2023, 24(3), 1990. doi: 10.3390/ijms24031990
  107. Van Baelen, A.-C.; Iturrioz, X.; Chaigneau, M.; Kessler, P.; Llorens-Cortes, C.; Servent, D.; Gilles, N.; Robin, P. Characterization of the First Animal Toxin Acting as an Antagonist on AT1 Receptor. International Journal of Molecular Sciences, 2023, 24(3), 2330. doi: 10.3390/ijms24032330
  108. Novopashina, D. S.; Dymova, M. A.; Davydova, A. S.; Meschaninova, M. I.; Malysheva, D. O.; Kuligina, E. V.; Richter, V. A.; Kolesnikov, I. A.; Taskaev, S. Y.; Vorobyeva, M. A. Aptamers for Addressed Boron Delivery in BNCT: Effect of Boron Cluster Attachment Site on Functional Activity. International Journal of Molecular Sciences, 2023, 24(1), 306. doi: 10.3390/ijms24010306
  109. Sapozhnikova, K. A.; Gulyak, E. L.; Brylev, V. A.; Misyurin, V. A.; Oreshkov, S. D.; Alexeeva, A. V.; Ryazantsev, D. Y.; Simonova, M. A.; Ryabukhina, E. V.; Popova, G. P.; Tikhonova, N. A.; Lyzhko, N. A.; Barmashov, A. E.; Misyurin, A. V.; Ustinov, A. V.; Alferova, V. A.; Korshun, V. A. Aminooxy Click Modification of a Periodate-Oxidized Immunoglobulin G: A General Approach to Antibody–Drug Conjugates with Dye-Mediated Expeditious Stoichiometry Control. International Journal of Molecular Sciences, 2023, 24(6), 5134. doi: 10.3390/ijms24065134
  110. Dong, N.; Liu, Z.; He, H.; Lu, Y.; Qi, J.; Wu, W. “Hook&Loop” Multivalent Interactions Based on Disk-Shaped Nanoparticles Strengthen Active Targeting. Journal of Controlled Release, 2023, 354, 279–293. doi: 10.1016/j.jconrel.2023.01.022
  111. Long, Y.; Guo, J.; Chen, J.; Sun, J.; Wang, H.; Peng, X.; Wang, Z.; Lai, W.; Liu, N.; Shu, L.; Chen, L.; Shi, Y.; Xiao, D.; Liu, S.; Tao, Y. GPR162 Activates STING Dependent DNA Damage Pathway as a Novel Tumor Suppressor and Radiation Sensitizer. Signal Transduction and Targeted Therapy, 2023, 8(1), 48. doi: 10.1038/s41392-022-01224-3
  112. Modrzycka, S.; Kołt, S.; Adams, T. E.; Potoczek, S.; Huntington, J. A.; Kasperkiewicz, P.; Drąg, M. Fluorescent Activity-Based Probe To Image and Inhibit Factor XIa Activity in Human Plasma. J. Med. Chem., 2023, 66(6), 3785–3797. doi: 10.1021/acs.jmedchem.2c00845
  113. McMahon, N. P.; Jones, J. A.; Anderson, A. N.; Dietz, M. S.; Wong, M. H.; Gibbs, S. L. Flexible Cyclic Immunofluorescence (CyCIF) Using Oligonucleotide Barcoded Antibodies. Cancers, 2023, 15(3), 827. doi: 10.3390/cancers15030827
  114. Han, S.; da Costa Marques, R.; Simon, J.; Kaltbeitzel, A.; Koynov, K.; Landfester, K.; Mailänder, V.; Lieberwirth, I. Endosomal Sorting Results in a Selective Separation of the Protein Corona from Nanoparticles. Nature Communications, 2023, 14(1), 295. doi: 10.1038/s41467-023-35902-9
  115. Saud, K. T.; Xu, J.; Wilkanowicz, S.; He, Y.; Moon, J. J.; Solomon, M. J. Electrosprayed Microparticles from Inulin and Poly(Vinyl) Alcohol for Colon Targeted Delivery of Prebiotics. Food Hydrocolloids, 2023, 140, 108625. doi: 10.1016/j.foodhyd.2023.108625.
  116. Schraven, S.; Rosenhain, S.; Brueck, R.; Wiechmann, T. M.; Pola, R.; Etrych, T.; Lederle, W.; Lammers, T.; Gremse, F.; Kiessling, F. Dye Labeling for Optical Imaging Biases Drug Carriers’ Biodistribution and Tumor Uptake. Nanomedicine: Nanotechnology, Biology and Medicine, 2023, 48, 102650. doi: 10.1016/j.nano.2023.102650
  117. Al-Nakashli, R.; Raveendran, R.; Khine, Y. Y.; Cao, C.; McKay, S.; Lu, H.; Stenzel, M. H. Drug-Loading Content Influences Cellular Uptake of Polymer-Coated Nanocellulose. Mol. Pharmaceutics, 2023, 20(4), 2017–2028. doi: 10.1021/acs.molpharmaceut.2c00997
  118. Yi, G.; Sung, Y.; Kim, C.; Ra, J. S.; Hirakawa, H.; Kato, T. A.; Fujimori, A.; Kim, H.; Takata, K. DNA Polymerase θ-Mediated Repair of High LET Radiation-Induced Complex DNA Double-Strand Breaks. Nucleic Acids Research, 2023, 51(5), 2257–2269. doi: 10.1093/nar/gkad076
  119. Chetverikov, P. E.; Craemer, C.; Gankevich, V. D.; Kremenetskaya, M. V.; Kuzmin, I. V.; Zhuk, A. S. Endoparasitic Gall Mites: Two New Novophytoptus Species (Eriophyoidea, Phytoptidae) from Southern African Sedges (Cyperaceae, Carex) and New Hypotheses on the Phylogeny of Novophytoptines. Diversity, 2023, 15(3), 416;. doi: 10.3390/d15030416
  120. Joo, S.-H.; Kim, J.; Hong, J.; Fakhraei Lahiji, S.; Kim, Y.-H. Dissolvable Self-Locking Microneedle Patches Integrated with Immunomodulators for Cancer Immunotherapy. Advanced Materials, 2023, 35(10), 2209966. doi: 10.1002/adma.202209966
  121. Zhang, H.; Guo, J.; Wang, Z.; Wang, N.; Feng, N.; Zhang, Y. Diethylene Glycol Monoethyl Ether-Mediated Nanostructured Lipid Carriers Enhance Trans -Ferulic Acid Delivery by Caco-2 Cells Superior to Solid Lipid Nanoparticles. Acta Pharmaceutica, 2023, 73(1), 133–143. doi: 10.2478/acph-2023-0009
  122. Jiang, Y.; Lyu, Z.; Ralahy, B.; Liu, J.; Roussel, T.; Ding, L.; Tang, J.; Kosta, A.; Giorgio, S.; Tomasini, R.; Liang, X.-J.; Dusetti, N.; Iovanna, J.; Peng, L. Dendrimer Nanosystems for Adaptive Tumor-Assisted Drug Delivery via Extracellular Vesicle Hijacking. Proc. Natl. Acad. Sci. U.S.A., 2023, 120(7), e2215308120. doi: 10.1073/pnas.2215308120
  123. Strasser, P.; Montsch, B.; Weiss, S.; Sami, H.; Kugler, C.; Hager, S.; Schueffl, H.; Mader, R.; Brüggemann, O.; Kowol, C. R.; Ogris, M.; Heffeter, P.; Teasdale, I. Degradable Bottlebrush Polypeptides and the Impact of Their Architecture on Cell Uptake, Pharmacokinetics, and Biodistribution In Vivo. Small, 2023, 19(22), 2300767. doi: 10.1002/smll.202300767
  124. Gao, W.; He, J.; Chen, L.; Meng, X.; Ma, Y.; Cheng, L.; Tu, K.; Gao, X.; Liu, C.; Zhang, M.; Fan, K.; Pang, D.-W.; Yan, X. Deciphering the Catalytic Mechanism of Superoxide Dismutase Activity of Carbon Dot Nanozyme. Nature Communications, 2023, 14(1), 160. doi: 10.1038/s41467-023-35828-2
  125. Lin, W.; Gandhi, S.; Bhattarai, P.; Kasa, K.; Kizil, C.; Zhang, Y. Combining High Throughput Array Synthesis and Growth Algorithm to Discover TNF-α Binders with New Structures and Properties. European Journal of Medicinal Chemistry, 2023, 248, 115078. doi: 10.1016/j.ejmech.2022.115078
  126. Eljack, S.; Allard-Vannier, E.; Misericordia, Y.; Hervé-Aubert, K.; Aubrey, N.; Chourpa, I.; Faggad, A.; David, S. Combination of Nanovectorized SiRNA Directed against Survivin with Doxorubicin for Efficient Anti-Cancer Activity in HER2+ Breast Cancer Cells. Pharmaceutics, 2023, 14(11), 2537. doi: 10.3390/pharmaceutics14112537
  127. Catania, G.; Rodella, G.; Vanvarenberg, K.; Préat, V.; Malfanti, A. Combination of Hyaluronic Acid Conjugates with Immunogenic Cell Death Inducer and CpG for Glioblastoma Local Chemo-Immunotherapy Elicits an Immune Response and Induces Long-Term Survival. Biomaterials, 2023, 294, 122006. doi: 10.1016/j.biomaterials.2023.122006
  128. Bagdanoff, J. T.; Smith, T. M.; Allan, M.; O’Donnell, P.; Nguyen, Z.; Moore, E. A.; Baird, J.; Wang, S.; Subramanian, V.; Tigani, B.; Nettleton, D. O.; Monovich, L. G.; Lewis, I.; Flyer, A. N.; Granda, B.; Blankenship, J. W.; Barnes-Seeman, D.; Clairmont, K. B. Clearance of Plasma PCSK9 via the Asialoglycoprotein Receptor Mediated by Heterobifunctional Ligands. Cell Chemical Biology, 2023, 30(1), 97-109.e9. doi: 10.1016/j.chembiol.2022.12.003
  129. Sousa De Almeida, M.; Roshanfekr, A.; Balog, S.; Petri-Fink, A.; Rothen-Rutishauser, B. Cellular Uptake of Silica Particles Influences EGFR Signaling Pathway and Is Affected in Response to EGF. IJN, 2023, 18, 1047–1061. doi: 10.2147/IJN.S388557
  130. Neupane, Y. R.; Handral, H. K.; Alkaff, S. A.; Chng, W. H.; Venkatesan, G.; Huang, C.; Lee, C. K.; Wang, J.-W.; Sriram, G.; Dienzo, R. A.; Lu, W. F.; Ali, Y.; Czarny, B.; Pastorin, G. Cell-Derived Nanovesicles from Mesenchymal Stem Cells as Extracellular Vesicle-Mimetics in Wound Healing. Acta Pharmaceutica Sinica B, 2023, 13(5), 1887–1902. doi: 10.1016/j.apsb.2022.10.022
  131. Komkova, M. A.; Shavokshina, V. A.; Zarochintsev, A. A.; Melnik, D. M.; Aparin, I. O.; Zatsepin, T. S.; Karyakin, A. A. Catalytically Synthesized Prussian Blue Nanozymes as Labels for Electrochemical DNA/RNA Sensors. Talanta, 2023, 257, 124337. doi: 10.1016/j.talanta.2023.124337
  132. Chen, H.; Li, Y.; Li, L.; Yang, Z.; Wen, Z.; Liu, L.; Liu, H.; Chen, Y. Carrier-Free Subunit Nanovaccine Amplifies Immune Responses against Tumors and Viral Infections. Acta Biomaterialia, 2023, 158, 525–534. doi: 10.1016/j.actbio.2022.12.042
  133. Bunce, C.; Barske, L.; Zhang, G.; Capel, B. Biased Precursor Ingression Underlies the Center-to-Pole Pattern of Male Sex Determination in Mouse. Development, 2023, 150(5), dev201060. doi: 10.1242/dev.201060
  134. Moiseeva, N.; Eroshenko, D.; Laletina, L.; Rybalkina, E.; Susova, O.; Karamysheva, A.; Tolmacheva, I.; Nazarov, M.; Grishko, V. The Molecular Mechanisms of Oleanane Aldehyde-β-Enone Cytotoxicity against Doxorubicin-Resistant Cancer Cells. Biology, 2023, 12(3), 415. doi: 10.3390/biology12030415
  135. Du, G.; Zhao, L.; Zheng, Y.; Belfetmi, A.; Cai, T.; Xu, B.; Heyninck, K.; Van Den Heede, K.; Buyse, M.-A.; Fontana, P.; Bowman, M.; Lin, L.-L.; Wu, H.; Chou, J. J. Autoinhibitory Structure of Preligand Association State Implicates a New Strategy to Attain Effective DR5 Receptor Activation. Cell Research, 2023, 33(2), 131–146. doi: 10.1038/s41422-022-00755-2
  136. Williams, C.; Dong, K. C.; Arkinson, C.; Martin, A. The Ufd1 Cofactor Determines the Linkage Specificity of Polyubiquitin Chain Engagement by the AAA+ ATPase Cdc48. Molecular Cell, 2023, 83(5), 759-769.e7. doi: 10.1016/j.molcel.2023.01.016
  137. Komaniecki, G.; Camarena, M. D. C.; Gelsleichter, E.; Mendoza, R.; Subler, M.; Windle, J. J.; Dozmorov, M. G.; Lai, Z.; Sarkar, D.; Lin, H. Astrocyte Elevated Gene-1 Cys75 S-Palmitoylation by ZDHHC6 Regulates Its Biological Activity. Biochemistry, 2023, 62(2), 543–553. doi: 10.1021/acs.biochem.2c00583
  138. Erstling, J. A.; Naguib, N.; Hinckley, J. A.; Lee, R.; Feuer, G. B.; Tallman, J. F.; Tsaur, L.; Tang, D.; Wiesner, U. B. Antibody Functionalization of Ultrasmall Fluorescent Core–Shell Aluminosilicate Nanoparticle Probes for Advanced Intracellular Labeling and Optical Super Resolution Microscopy. Chem. Mater., 2023, 35(3), 1047–1061. doi: 10.1021/acs.chemmater.2c02963
  139. Mei, X.; Li, J.; Wang, Z.; Zhu, D.; Huang, K.; Hu, S.; Popowski, K. D.; Cheng, K. An Inhaled Bioadhesive Hydrogel to Shield Non-Human Primates from SARS-CoV-2 Infection. Nature Materials, 2023, 22(7), 903–912. doi: 10.1038/s41563-023-01475-7
  140. Hade, M. D.; Suire, C. N.; Suo, Z. An Effective Peptide-Based Platform for Efficient Exosomal Loading and Cellular Delivery of a MicroRNA. ACS Appl. Mater. Interfaces, 2023, 15(3), 3851–3866. doi: 10.1021/acsami.2c20728
  141. Dzhuzha, A. Y.; Tarasenko, I. I.; Atanase, L. I.; Lavrentieva, A.; Korzhikova-Vlakh, E. G. Amphiphilic Polypeptides Obtained by the Post-Polymerization Modification of Poly(Glutamic Acid) and Their Evaluation as Delivery Systems for Hydrophobic Drugs. International Journal of Molecular Sciences, 2023, 24(2), 1049. doi: 10.3390/ijms24021049
  142. Tola, A. J.; Missihoun, T. D. Ammonium Sulfate-Based Prefractionation Improved Proteome Coverage and Detection of Carbonylated Proteins in Arabidopsis Thaliana Leaf Extract. Planta, 2023, 257(3), 62. doi: 10.1007/s00425-023-04083-6
  143. De Prisco, N.; Ford, C.; Elrod, N. D.; Lee, W.; Tang, L. C.; Huang, K.-L.; Lin, A.; Ji, P.; Jonnakuti, V. S.; Boyle, L.; Cabaj, M.; Botta, S.; Õunap, K.; Reinson, K.; Wojcik, M. H.; Rosenfeld, J. A.; Bi, W.; Tveten, K.; Prescott, T.; Gerstner, T.; Schroeder, A.; Fong, C.-T.; George-Abraham, J. K.; Buchanan, C. A.; Hanson-Khan, A.; Bernstein, J. A.; Nella, A. A.; Chung, W. K.; Brandt, V.; Jovanovic, M.; Targoff, K. L.; Yalamanchili, H. K.; Wagner, E. J.; Gennarino, V. A. Alternative Polyadenylation Alters Protein Dosage by Switching between Intronic and 3′UTR Sites. Sci. Adv., 2023, 9(7), eade4814. doi: 10.1126/sciadv.ade4814
  144. Shin, J.; Mir, H.; Khurram, M. A.; Fujihara, K. M.; Dynlacht, B. D.; Cardozo, T. J.; Possemato, R. Allosteric Regulation of CAD Modulates de Novo Pyrimidine Synthesis during the Cell Cycle. Nature Metabolism, 2023, 5(2), 277–293.. doi: 10.1038/s42255-023-00735-9
  145. Zhou, L.; He, F.; Xiang, X.; Dong, C.; Xiang, T.; Li, X.; Li, H.; Bu, L.; Wang, Y.; Ma, X. Radioactive and Fluorescent Dual Modality Cysteine Cathepsin B Activity-Based Probe for Cancer Theranostics. Mol. Pharmaceutics, 2023, 20(7), 3539–3548. doi: 10.1021/acs.molpharmaceut.3c00148
  146. Chen, P.; Pan, K.; Song, N.; Yang, Y.; Gu, C.; Zhong, P.; Li, L.; Li, M.; Zhang, Y.; Dai, Z.; Shangguan, L.; Lei, C.; Liu, Z.; Zhang, J.; Tang, R.; Liu, C.; Fan, S.; Lin, X. A Natural Extracellular Matrix Hydrogel through Selective Nutrient Restriction for Hyperinflammatory Starvation Therapy. Matter, 2023, 6(2), 397–428. doi: 10.1016/j.matt.2022.12.002
  147. Luo, M.; Li, Y.; Peng, B.; White, J.; Mäkilä, E.; Tong, W. Y.; Jonathan Choi, C. H.; Day, B.; Voelcker, N. H. A Multifunctional Porous Silicon Nanocarrier for Glioblastoma Treatment. Mol. Pharmaceutics, 2023, 20(1), 545–560. doi: 10.1021/acs.molpharmaceut.2c00763
  148. Luo, M.; Li, Y.; Peng, B.; White, J.; Mäkilä, E.; Tong, W. Y.; Jonathan Choi, C. H.; Day, B.; Voelcker, N. H. A Multifunctional Porous Silicon Nanocarrier for Glioblastoma Treatment. Mol. Pharmaceutics, 2023, 20(1), 545–560. doi: 10.1021/acs.molpharmaceut.2c00763
  149. Dirscherl, C. F.; Ianeselli, A.; Tetiker, D.; Matreux, T.; Queener, R. M.; Mast, C. B.; Braun, D. A Heated Rock Crack Captures and Polymerizes Primordial DNA and RNA. Phys. Chem. Chem. Phys., 2023, 25(4), 3375–3386. doi: 10.1039/D2CP04538A
  150. Zhao, Z.; A. Ortega-Rivera, O.; Hun Chung, Y.; Simms, A.; F. Steinmetz, N. A Co-Formulated Vaccine of Irradiated Cancer Cells and Cowpea Mosaic Virus Improves Ovarian Cancer Rejection. Journal of Materials Chemistry B, 2023, 11(24), 5429–5441. doi: 10.1039/D2TB02355E
  151. Kowalski, K. A. Brief Survey on the Application of Metal-Catalyzed Azide–Alkyne Cycloaddition Reactions to the Synthesis of Ferrocenyl-x-1,2,3-Triazolyl-R (x = None or a Linker and R = Organic Entity) Compounds with Anticancer Activity. Coordination Chemistry Reviews, 2023, 479, 214996. doi: 10.1016/j.ccr.2022.214996
  152. Radion, E. I.; Mukhin, V. E.; Kholodova, A. V.; Vladimirov, I. S.; Alsaeva, D. Y.; Zhdanova, A. S.; Ulasova, N. Y.; Bulanova, N. V.; Makarov, V. V.; Keskinov, A. A.; Yudin, S. M. Functional Characteristics of Serum Anti-SARS-CoV-2 Antibodies against Delta and Omicron Variants after Vaccination with Sputnik V. Viruses, 2023, 15(6). doi: 10.3390/v15061349
  153. Visentin, A.; Demitroff, N.; Salgueiro, M.; Borkosky, S. S.; Uversky, V. N.; Camporeale, G.; de Prat-Gay, G. Assembly of the Tripartite and RNA Condensates of the Respiratory Syncytial Virus Factory Proteins In Vitro: Role of the Transcription Antiterminator M2-1. Viruses, 2023, 15(6), 1329. doi: 10.3390/v15061329
  154. Tong, Z.; Xie, Y.; Arno, M. C.; Zhang, Y.; Manners, I.; O’Reilly, R. K.; Dove, A. P. Uniform Segmented Platelet Micelles with Compositionally Distinct and Selectively Degradable Cores. Nature Chemistry, 2023, 15(6), 824–831. doi: 10.1038/s41557-023-01177-2
  155. Li, Z.; Zhang, L.; Zhou, L.; Li, X.; Zhao, Y.; Wang, J. Tunable Catalytic Release of Nitric Oxide via Copper-Loaded Coatings on Titanium Nanotubes for Regulating Biological Performance. Biosurface and Biotribology, 2023, 9(2), 45–57. doi: 10.1049/bsb2.12060
  156. Itzhaki, E.; Chausky-Barzakh, E.; Atkins, A.; Bareket-Samish, A.; Stemmer, S. M.; Margel, S.; Moskovits, N. Tumor-Targeted Poly(ArgGlyAsp) Nanocapsules for Personalized Cancer Therapy – In Vivo Study. Advanced Therapeutics, 2023, 6(6), 2200337. doi: 10.1002/adtp.202200337
  157. Deng, W.; Ren, G.; Luo, J.; Gao, S.; Huang, W.; Liu, W.; Ye, S. TRPM7 Mediates Endoplasmic Reticulum Stress and Ferroptosis in Sepsis-Induced Myocardial Injury. Journal of Bioenergetics and Biomembranes, 2023, 55(3), 207–217. doi: 10.1007/s10863-023-09968-5
  158. Nanjaiah, H.; Moudgil, K. D. The Utility of Peptide Ligand-Functionalized Liposomes for Subcutaneous Drug Delivery for Arthritis Therapy. International Journal of Molecular Sciences, 2023, 24(8), 6883. doi: 10.3390/ijms24086883
  159. Hiroki, H.; Ishii, Y.; Piao, J.; Namikawa, Y.; Masutani, M.; Honda, H.; Akahane, K.; Inukai, T.; Morio, T.; Takagi, M. Targeting Poly(ADP)Ribose Polymerase in BCR/ABL1-Positive Cells. Scientific Reports, 2023, 13(1), 7588. doi: 10.1038/s41598-023-33852-2
  160. Subrahmanyam, N.; Yathavan, B.; Yu, S. M.; Ghandehari, H. Targeting Intratibial Osteosarcoma Using Water-Soluble Copolymers Conjugated to Collagen Hybridizing Peptides. Mol. Pharmaceutics, 2023, 20(3), 1670–1680. doi: 10.1021/acs.molpharmaceut.2c00880
  161. Ding, T.; Ji, J.; Zhang, W.; Liu, Y.; Liu, B.; Han, Y.; Chen, C.; Yu, L. The Phosphatidylinositol (4,5)-Bisphosphate-Rab35 Axis Regulates Migrasome Formation. Cell Research, 2023, 33(8), 617–627. doi: 10.1038/s41422-023-00811-5
  162. Damstra, H. G. J.; Mohar, B.; Eddison, M.; Akhmanova, A.; Kapitein, L. C.; Tillberg, P. W. Ten-Fold Robust Expansion Microscopy. Bio Protoc, 2023, 13(12), e4698. doi: 10.21769/BioProtoc.4698
  163. Wiesner, W.; Kühnel, R. M.; Pomorski, T. G. Synthesis and Purification of Lipid-Conjugated Fluorescent PH Sensors. Bio Protoc, 2023, 13(11), e4694. doi: 10.21769/BioProtoc.4694
  164. Dang, W.; Xing, B.; Jia, X.; Zhang, Y.; Jia, B.; Yu, C.; He, J.; Li, Z.; Li, H.; Liu, Z. Subcellular Organelle-Targeted Nanostructured Lipid Carriers for the Treatment of Metastatic Breast Cancer. IJN, 2023, 18, 3047–3068. doi: 10.2147/IJN.S413680
  165. Sun, X.-L.; Chen, Z.-H.; Guo, X.; Wang, J.; Ge, M.; Wong, S. Z. H.; Wang, T.; Li, S.; Yao, M.; Johnston, L. A.; Wu, Q.-F. Stem Cell Competition Driven by the Axin2-P53 Axis Controls Brain Size during Murine Development. Developmental Cell, 2023, 58(9), 744-759.e11. doi: 10.1016/j.devcel.2023.03.016
  166. Rodgers, M. L.; O’Brien, B.; Woodson, S. A. Small RNAs and Hfq Capture Unfolded RNA Target Sites during Transcription. Molecular Cell, 2023, 83(9), 1489-1501.e5. doi: 10.1016/j.molcel.2023.04.003.
  167. Shevchuk, A. I.; Svinko, V. O.; Smirnov, A. N.; Solovyeva, E. V. SERS Study of Cyanine Dyes: Optimization of Metal Core and Molecular Label Choice for Plasmonic Nanotags. Dyes and Pigments, 2023, 216, 111329. doi: 10.1016/j.dyepig.2023.111329.
  168. Ji, Y.; Chakraborty, T.; Wegner, S. V. Self-Regulated and Bidirectional Communication in Synthetic Cell Communities. ACS Nano, 2023, 17(10), 8992–9002. doi: 10.1021/acsnano.2c09908
  169. Sahu, A.; Min, K.; Jeon, S. H.; Kwon, K.; Tae, G. Self-Assembled Hemin-Conjugated Heparin with Dual-Enzymatic Cascade Reaction Activities for Acute Kidney Injury. Carbohydrate Polymers, 2023, 316, 121088. doi: 10.1016/j.carbpol.2023.121088
  170. Gu, J.; Sun, J.; Tian, K.; Bian, J.; Peng, J.; Xu, S.; Zhao, L. Reversal of Hepatic Fibrosis by the Co-Delivery of Drug and Ribonucleoprotein-Based Genome Editor. Biomaterials, 2023, 298, 122133. doi: 10.1016/j.biomaterials.2023.122133
  171. Martín-Asensio, A.; Dávila, S.; Cacheux, J.; Lindstaedt, A.; Dziadosz, A.; Witt, D.; Calero, M.; Balaz, I.; Rodríguez, I. Recapitulating Solid Stress on Tumor on a Chip for Nanomedicine Diffusive Transport Prediction. Advanced NanoBiomed Research, 2023, 3(6), 2200164. doi: 10.1002/anbr.202200164
  172. Ardana, A.; Ghosh, S.; Huda, P.; Fletcher, N. L.; Thurecht, K. J.; Williams, C. C. RAFT Polymer–Antibody Conjugation: Squaramide Ester Chemistry Leads to Conjugates with a Therapeutic Anti-EGFR Antibody with Full Retention of Activity and Increased Tumor Uptake In Vivo. Mol Pharmaceutics, 2023, 20(6), 3073–3087. doi: 10.1021/acs.molpharmaceut.3c00085
  173. Lu, Y.; Zhang, M.; Zhang, J.; Jiang, M.; Bai, G. Psoralen Prevents the Inactivation of Estradiol and Treats Osteoporosis via Covalently Targeting HSD17B2. Journal of Ethnopharmacology, 2023, 311, 116426. doi: 10.1016/j.jep.2023.116426
  174. Xu, X.; Wang, C.; Guan, W.; Wang, F.; Li, X.; Yuan, J.; Xu, G. Protoporphyrin IX-Loaded Albumin Nanoparticles Reverse Cancer Chemoresistance by Enhancing Intracellular Reactive Oxygen Species. Nanomedicine: Nanotechnology, Biology and Medicine, 2023, 51, 102688. doi: 10.1016/j.nano.2023.102688
  175. Zueva, A. O.; Silchenko, A. S.; Rasin, A. B.; Malyarenko, O. S.; Kusaykin, M. I.; Kalinovsky, A. I.; Ermakova, S. P. Production of High- and Low-Molecular Weight Fucoidan Fragments with Defined Sulfation Patterns and Heightened in Vitro Anticancer Activity against TNBC Cells Using Novel Endo-Fucanases of the GH107 Family. Carbohydrate Polymers, 2023, 318, 121128. doi: 10.1016/j.carbpol.2023.121128
  176. Luo, J.; Zhao, X.; Guo, B.; Han, Y. Preparation, Thermal Response Mechanisms and Biomedical Applications of Thermosensitive Hydrogels for Drug Delivery. Expert Opinion on Drug Delivery, 2023, 20(5), 641–672. doi: 10.1080/17425247.2023.2217377
  177. Guirguis, N.; Machuca-Parra, A. I.; Matoori, S. Portable Near-Infrared Fluorometer for a Liposomal Blood Lactate Assay. ACS Pharmacol Transl Sci, 2023, 6(6), 907–912. doi: 10.1021/acsptsci.3c00055
  178. Okamoto, W.; Usui, T.; Hasegawa, M.; Kobayashi, T.; Fujisawa, J.; Taguchi, K.; Matsumoto, K.; Kohno, M.; Iwazaki, M.; Shimano, S.; Nagao, I.; Toyoda, H.; Matsumura, N.; Tomiyasu, H.; Tochinai, R.; Komatsu, T. Polyoxazoline-Conjugated Porcine Serum Albumin as an Artificial Plasma Expander for Dogs. Sci Rep, 2023, 13(1), 9512. doi: 10.1038/s41598-023-35999-4
  179. Wu, Y.; Leyk, S.; Torabi, H.; Höhn, K.; Honecker, B.; Tauler, M. D. P. M.; Cadar, D.; Jacobs, T.; Bruchhaus, I.; Metwally, N. G. Plasmodium Falciparum Infection Reshapes the Human MicroRNA Profiles of Red Blood Cells and Their Extracellular Vesicles. iScience, 2023, 26(7), 107119. doi: 10.1016/j.isci.2023.107119
  180. Protas, V. V.; Pogossyan, G. P.; Li, K. G.; Zhumina, A. G.; Bisseneva, A. K.; Shaikina, D. N. Plasma 25-Hydroxyvitamin D Level and VDR Gene Single Nucleotide Polymorphism Rs2228570 Influence on COVID-19 Susceptibility among the Kazakh Ethnic Group—A Pilot Study. Nutrients, 2023, 15(7), 1781. doi: 10.3390/nu15071781
  181. Sandberg, E.; Piguet, J.; Kostiv, U.; Baryshnikov, G.; Liu, H.; Widengren, J. Photoisomerization of Heptamethine Cyanine Dyes Results in Red-Emissive Species: Implications for Near-IR, Single-Molecule, and Super-Resolution Fluorescence Spectroscopy and Imaging. J Phys Chem B, 2023, 127(14), 3208–3222. doi: 10.1021/acs.jpcb.2c08016
  182. Yao, P.; Wang, X.; Wang, Q.; Dai, Q.; Peng, Y.; Yuan, Q.; Mou, N.; Lv, S.; Weng, B.; Wang, Y.; Sun, F. Cyclic RGD-Functionalized PH/ROS Dual-Responsive Nanoparticle for Targeted Breast Cancer Therapy. Pharmaceutics, 2023, 15(7), 1827. doi: 10.3390/pharmaceutics15071827
  183. Deiss-Yehiely, E.; Cárcamo-Oyarce, G.; Berger, A. G.; Ribbeck, K.; Hammond, P. T. PH-Responsive, Charge-Reversing Layer-by-Layer Nanoparticle Surfaces Enhance Biofilm Penetration and Eradication. ACS Biomater Sci Eng, 2023, 9(8), 4794–4804. doi: 10.1021/acsbiomaterials.3c00481
  184. Ponomartsev, N.; Zilov, D.; Gushcha, E.; Travina, A.; Sergeev, A.; Enukashvily, N. Overexpression of Pericentromeric HSAT2 DNA Increases Expression of EMT Markers in Human Epithelial Cancer Cell Lines. International Journal of Molecular Sciences, 2023, 24(8), 6918. doi: 10.3390/ijms24086918
  185. Schvartzman, J.-M.; Forsyth, G.; Walch, H.; Chatila, W.; Taglialatela, A.; Lee, B. J.; Zhu, X.; Gershik, S.; Cimino, F. V.; Santella, A.; Menghrajani, K.; Ciccia, A.; Koche, R.; Sánchez-Vega, F.; Zha, S.; Thompson, C. B. Oncogenic IDH Mutations Increase Heterochromatin-Related Replication Stress without Impacting Homologous Recombination. Molecular Cell, 2023, 83(13), 2347-2356.e8. doi: 10.1016/j.molcel.2023.05.026
  186. Pinto, R. M.; Yazdani, S.; Seabra, C. L.; De Jonge, M.; Izci, M.; Cruz, R.; Casal, S.; Soenen, S. J.; Reis, S.; Nunes, C.; Van Dijck, P. Non Disseminative Nano-Strategy against in Vivo Staphylococcus Aureus Biofilms. npj Biofilms Microbiomes, 2023, 9(1), 1-15. doi: 10.1038/s41522-023-00405-4
  187. Zhao, Z.; Li, C.; Zhang, Y.; Li, C.; Chu, Y.; Li, X.; Liu, P.; Chen, H.; Wang, Y.; Su, B.; Chen, Q.; Sun, T.; Jiang, C. Nanomaterials with Dual Immunomodulatory Functions for Synergistic Therapy of Breast Cancer Brain Metastases. Bioactive Materials, 2023, 27, 474–487. doi: 10.1016/j.bioactmat.2023.04.021
  188. Naeimipour, S.; Boroojeni, F. R.; Lifwergren, P.; Selegård, R.; Aili, D. Multimodal andDynamic Cross-Linking of Modular Thiolated Alginate-Based Bioinks. Materials Today Advances, 2023, 19, 100415. doi: 10.1016/j.mtadv.2023.100415
  189. Hyun, G. H.; Jeong, D.-H.; Yang, Y. Y.; Cho, I. H.; Ha, Y.-J.; Xing, X.; Abbott, D. W.; Hsieh, Y. S. Y.; Kang, Y. P.; Cha, J.-H.; Hong, S.-S.; Lee, S. J.; Kim, Y.-S.; Kwon, S. W. Multivalent Carbohydrate Nanocomposites for Tumor Microenvironment Remodeling to Enhance Antitumor Immunity. ACS Nano, 2023, 17(12), 11567–11582. doi: 10.1021/acsnano.3c01645
  190. Ji, F.; Hur, M.; Hur, S.; Wang, S.; Sarkar, P.; Shao, S.; Aispuro, D.; Cong, X.; Hu, Y.; Li, Z.; Xue, M. Multiplex Protein Imaging through PACIFIC: Photoactive Immunofluorescence with Iterative Cleavage. ACS Bio Med Chem Au, 2023, 3(3), 283–294. doi: 10.1021/acsbiomedchemau.3c00018
  191. Smirnov, A. N.; Aslanov, S. F.; Danilov, D. V.; Kurapova, O. Yu.; Solovyeva, E. V. One-Pot Synthesis of Silica-Coated Gold Nanostructures Loaded with Cyanine 5.5 for Cell Imaging by SERS Spectroscopy. Nanomaterials, 2023, 13(7), 1267. doi: 10.3390/nano13071267
  192. Saveleva, M. S.; Lobanov, M. E.; Gusliakova, O. I.; Plastun, V. O.; Prikhozhdenko, E. S.; Sindeeva, O. A.; Gorin, D. A.; Mayorova, O. A. Mucoadhesive Emulsion Microgels for Intravesical Drug Delivery: Preparation, Retention at Urothelium, and Biodistribution Study. ACS Appl Mater Interfaces, 2023, 15(21), 25354–25368. doi: 10.1021/acsami.3c02741
  193. Gmoshinskiy, V. I.; Novozhilov, Yu. K.; Prikhodko, I. S.; Bortnikov, F. M.; Shchepin, O. N.; Schnittler, M. Morphology and phylogeny of Diderma aurantiacum (Myxomycetes) — a new species for Russia from the Far East. Novosti sistematiki nizshikh rastenii, 2023, 57(1), 27–42. doi: 10.31111/nsnr/2023.57.1.27
  194. Mustafa, R. A.; Parkkila, P.; Rosenholm, J. M.; Zhang, H.; Viitala, T. Monitoring Silica Core@shell Nanoparticle-Bacterial Film Interactions Using the Multi-Parametric Surface Plasmon Resonance Technique. Smart Medicine, 2023, 2(3), e20230012. doi: 10.1002/SMMD.20230012
  195. Salgueiro, M.; Camporeale, G.; Visentin, A.; Aran, M.; Pellizza, L.; Esperante, S. A.; Corbat, A.; Grecco, H.; Sousa, B.; Esperón, R.; Borkosky, S. S.; de Prat-Gay, G. Molten Globule Driven and Self-Downmodulated Phase Separation of a Viral Factory Scaffold. Journal of Molecular Biology, 2023, 435(16), 168153. doi: 10.1016/j.jmb.2023.168153
  196. Xavier da Silva, T. N.; Schulte, C.; Alves, A. N.; Maric, H. M.; Friedmann Angeli, J. P. Molecular Characterization of AIFM2/FSP1 Inhibition by IFSP1-like Molecules. Cell Death & Disease, 2023, 14(4), 281. doi: 10.1038/s41419-023-05787-z
  197. Wang, Y.; Ling, X.; Zhang, C.; Zou, J.; Luo, B.; Luo, Y.; Jia, X.; Jia, G.; Zhang, M.; Hu, J.; Liu, T.; Wang, Y.; Lu, K.; Li, D.; Ma, J.; Liu, C.; Su, Z. Modular Characterization of SARS-CoV-2 Nucleocapsid Protein Domain Functions in Nucleocapsid-like Assembly. Molecular Biomedicine, 2023, 4(1), 16. doi: 10.1186/s43556-023-00129-z
  198. Somsen, B. A.; Sijbesma, E.; Leysen, S.; Honzejkova, K.; Visser, E. J.; Cossar, P. J.; Obšil, T.; Brunsveld, L.; Ottmann, C. Molecular Basis and Dual Ligand Regulation of Tetrameric Estrogen Receptor α/14-3-3ζ Protein Complex. Journal of Biological Chemistry, 2023, 299(7), 104855. doi: 10.1016/j.jbc.2023.104855
  199. Tong, L.; Zhang, S.; Liu, Q.; Huang, C.; Hao, H.; Tan, M. S.; Yu, X.; Lou, C. K. L.; Huang, R.; Zhang, Z.; Liu, T.; Gong, P.; Ng, C. H.; Muthiah, M.; Pastorin, G.; Wacker, M. G.; Chen, X.; Storm, G.; Lee, C. N.; Zhang, L.; Yi, H.; Wang, J.-W. Milk-Derived Extracellular Vesicles Protect Intestinal Barrier Integrity in the Gut-Liver Axis. Sci Adv, 2023, 9(15), eade5041. doi: 10.1126/sciadv.ade5041
  200. Salova, V. D.; Kholdina, A. M.; Melnik, A. D.; Zayulina, K. S.; Elcheninov, A. G.; Klyukina, A. A.; Kublanov, I. V. Microbial Communities Associated with the White Sea Red Algae as a Source of Xylanolytic Microorganisms. Microbiology, 2023, 92(3), 418–426. doi: 10.1134/S002626172360026X
  201. Das, S. K.; Huynh, M. T.; Gao, J.; Sengupta, B.; Yadav, S. P.; Lee, T.-H. Methods to Investigate Nucleosome Structure and Dynamics with Single-Molecule FRET. Methods, 2023, 215, 17–27. doi: 10.1016/j.ymeth.2023.05.003
  202. Park, H. H.; Wang, B.; Moon, S.; Jepson, T.; Xu, K. Machine-Learning-Powered Extraction of Molecular Diffusivity from Single-Molecule Images for Super-Resolution Mapping. Commun Biol, 2023, 6(1), 1-8. doi: 10.1038/s42003-023-04729-x
  203. Watanabe, T.; Mizuno, H. L.; Norimatsu, J.; Obara, T.; Cabral, H.; Tsumoto, K.; Nakakido, M.; Kawauchi, D.; Anraku, Y. Ligand Installation to Polymeric Micelles for Pediatric Brain Tumor Targeting. Polymers, 2023, 15(7), 1808. doi: 10.3390/polym15071808
  204. Barkovich, K. J.; Zhao, Z.; Steinmetz, N. F. IRGD-Targeted Physalis Mottle Virus Like Nanoparticles for Targeted Cancer Delivery. Small Science, 2023, 3(8), 2300067. doi: 10.1002/smsc.202300067
  205. Matthews, M. D.; Cook, E.; Naguib, N.; Wiesner, U. B.; Lewis, K. J. Intravital Imaging of Osteocyte Integrin Dynamics with Locally Injectable Fluorescent Nanoparticles. Bone, 2023, 174, 116830. doi: 10.1016/j.bone.2023.116830
  206. Lam, A. D.; Styles, I. K.; Senyschyn, D.; Cao, E.; Anshabo, A.; Abdallah, M.; Mikrani, R.; Nowell, C. J.; Porter, C. J. H.; Feeney, O. M.; Trevaskis, N. L. Intra-Articular Injection of a B Cell Depletion Antibody Enhances Local Exposure to the Joint-Draining Lymph Node in Mice with Collagen-Induced Arthritis. Mol Pharmaceutics, 2023, 20(4), 2053–2066. doi: 10.1021/acs.molpharmaceut.2c01041
  207. Liu, C.; Tong, Y. W. Interfacial Polyelectrolyte Complexation-Inspired Bioprinting of Vascular Constructs. ACS Appl Mater Interfaces, 2023, 15(17), 20712–20725. doi: 10.1021/acsami.3c01199
  208. Kolyvanova, M. A.; Klimovich, M. A.; Dement’eva, O. V.; Rudoy, V. M.; Kuzmin, V. A.; Trofimov, A. V.; Morozov, V. N. Interaction of Gold Nanoparticles with Cyanine Dyes in Cholesteric DNA Submicroparticles: Impact of the Way of Their Introduction into the System. Russian Journal of Physical Chemistry B, 2023, 17(1), 206–214. doi: 10.1134/S1990793123010062
  209. Chetverikov, P. E.; Craemer, C.; Gankevich, V. D.; Zhuk, A. S. Integrative Taxonomy of the Gall Mite Nothopoda Todeica n. Sp. (Eriophyidae) from the Disjunct Afro-Australasian Fern Todea Barbara: Morphology, Phylogeny, and Mitogenomics. Insects, 2023, 14(6), 507. doi: 10.3390/insects14060507
  210. Schoenmakers, L. L. J.; Yewdall, N. A.; Lu, T.; André, A. A. M.; Nelissen, Frank. H. T.; Spruijt, E.; Huck, W. T. S. In Vitro Transcription–Translation in an Artificial Biomolecular Condensate. ACS Synth Biol, 2023, 12(7), 2004–2014. doi: 10.1021/acssynbio.3c00069
  211. Lu, J.; Zhu, X.; Zhang, M.; Jiang, X.; Guo, W.; Jiang, F.; Cao, F. In Vitro and in Vivo Assessment of Structural Integrity for HPCD Complex@Liposome Nanocomposites from Ocular Surface to the Posterior Segment of the Eye. Carbohydrate Polymers, 2023, 315, 120960. doi: 10.1016/j.carbpol.2023.120960
  212. Godino, E.; Restrepo Sierra, A. M.; Danelon, C. Imaging Flow Cytometry for High-Throughput Phenotyping of Synthetic Cells. ACS Synth Biol, 2023, 12(7), 2015–2028. doi: 10.1021/acssynbio.3c00074
  213. Sim, J.; Li, M.; Park, K. M.; Kim, K. Identification of Mitochondrial Proteins Associated with Cyanine 5 Using a Combination of Affinity-Based Photocrosslinking with Bio-Orthogonal Supramolecular Latching. J. Porphyrins Phthalocyanines, 2023, 27(07n10), 1148–1155. doi: 10.1142/S108842462350058X
  214. Nasimi, H.; Madsen, J. S.; Zedan, A. H.; Malmendal, A.; Osther, P. J. S.; Alatraktchi, F. A. Identification of Early Stage and Metastatic Prostate Cancer Using Electrochemical Detection of Beta-2-Microglobulin in Urine Samples from Patients. Scientific Reports, 2023, 13(1), 10658. doi: 10.1038/s41598-023-37886-4
  215. Malfanti, A.; Bausart, M.; Vanvarenberg, K.; Ucakar, B.; Préat, V. Hyaluronic Acid-Antigens Conjugates Trigger Potent Immune Response in Both Prophylactic and Therapeutic Immunization in a Melanoma Model. Drug Delivery and Translational Research, 2023, 13(10), 2550–2567. doi: 10.1007/s13346-023-01337-4
  216. Purohit, M. P.; Kar, A. K.; Kumari, M.; Ghosh, D.; Patnaik, S. Heparin Biofunctionalized Selenium Nanoparticles as Potential Antiangiogenic–Chemotherapeutic Agents for Targeted Doxorubicin Delivery. ACS Appl Mater Interfaces, 2023, 15(16), 19904–19920. doi: 10.1021/acsami.3c00219
  217. Kim, G. B.; Kim, S.; Hwang, Y. H.; Kim, S.; Lee, I.; Kim, S. A.; Goo, J.; Yang, Y.; Jeong, C.; Nam, G.-H.; Kim, I.-S. Harnessing Oncolytic Extracellular Vesicles for Tumor Cell-Preferential Cytoplasmic Delivery of Misfolded Proteins for Cancer Immunotherapy. Small, 2023, 19(37), 2300527. doi: 10.1002/smll.202300527
  218. Liu, H.-J.; Chen, W.; Wu, G.; Zhou, J.; Liu, C.; Tang, Z.; Huang, X.; Gao, J.; Xiao, Y.; Kong, N.; Joshi, N.; Cao, Y.; Abdi, R.; Tao, W. Glutathione-Scavenging Nanoparticle-Mediated PROTACs Delivery for Targeted Protein Degradation and Amplified Antitumor Effects. Advanced Science, 2023, 10(16), 2207439. doi: 10.1002/advs.202207439
  219. Lu, Y.; Zhou, J.; Wang, Q.; Cai, J.; Yu, B.; Dai, Q.; Bao, Y.; Chen, R.; Zhang, Z.; Zhang, D.; Hou, T. Glucocorticoid-Loaded PH/ROS Dual-Responsive Nanoparticles Alleviate Joint Destruction by Downregulating the NF-ΚB Signaling Pathway. Acta Biomaterialia, 2023, 164, 458–473. doi: 10.1016/j.actbio.2023.04.012
  220. Kim, J.; Won, J.; Chung, D. K.; Lee, H. H. FRET Analysis of the Temperature-Induced Structural Changes in Human TRPV3. Scientific Reports, 2023, 13(1), 10108. doi: 10.1038/s41598-023-36885-9
  221. Wang, Q.; Yu, Y.; Chang, Y.; Xu, X.; Wu, M.; Ediriweera, G. R.; Peng, H.; Zhen, X.; Jiang, X.; Searles, D. J.; Fu, C.; Whittaker, A. K. Fluoropolymer-MOF Hybrids with Switchable Hydrophilicity for 19F MRI-Monitored Cancer Therapy. ACS Nano, 2023, 17(9), 8483–8498. doi: 10.1021/acsnano.3c00694
  222. Maltseva, D.; Chatterjee, S.; Yu, C.-C.; Brzezinski, M.; Nagata, Y.; Gonella, G.; Murthy, A. C.; Stachowiak, J. C.; Fawzi, N. L.; Parekh, S. H.; Bonn, M. Fibril Formation and Ordering of Disordered FUS LC Driven by Hydrophobic Interactions. Nature Chemistry, 2023, 15(8), 1146–1154. doi: 10.1038/s41557-023-01221-1
  223. Byun, J.; Wu, Y.; Lee, J.; Kim, J. S.; Shim, G.; Oh, Y.-K. External Cold Atmospheric Plasma-Responsive on-Site Hydrogel for Remodeling Tumor Immune Microenvironment. Biomaterials, 2023, 299, 122162. doi: 10.1016/j.biomaterials.2023.122162
  224. Rezaei, S.; de Araújo Júnior, R. F.; da Silva, I. L. G.; Schomann, T.; Eich, C.; Cruz, L. J. Erythrocyte−cancer Hybrid Membrane-Coated Reduction-Sensitive Nanoparticles for Enhancing Chemotherapy Efficacy in Breast Cancer. Biomaterials Advances, 2023, 151, 213456. doi: 10.1016/j.bioadv.2023.213456
  225. Ianshina, T.; Sidorin, A.; Petrova, K.; Shubert, M.; Makeeva, A.; Sambuk, E.; Govdi, A.; Rumyantsev, A.; Padkina, M. Effect of Methionine on Gene Expression in Komagataella Phaffii Cells. Microorganisms, 2023, 11(4), 877. doi: 10.3390/microorganisms11040877
  226. Aldag, P.; Rutkauskas, M.; Madariaga-Marcos, J.; Songailiene, I.; Sinkunas, T.; Kemmerich, F.; Kauert, D.; Siksnys, V.; Seidel, R. Dynamic Interplay between Target Search and Recognition for a Type I CRISPR-Cas System. Nature Communications, 2023, 14(1), 3654. doi: 10.1038/s41467-023-38790-1
  227. Prabhakar, A.; Pavlov, M. Y.; Zhang, J.; Indrisiunaite, G.; Wang, J.; Lawson, M. R.; Ehrenberg, M.; Puglisi, J. D. Dynamics of Release Factor Recycling during Translation Termination in Bacteria. Nucleic Acids Research, 2023, 52(11), 5774–5790. doi: 10.1093/nar/gkad286
  228. Konhäuser, M.; Kannaujiya, V. K.; Kaltbeitzel, J.; Winterwerber, P.; Böhm, E.; Breitenbach, B.; Wich, P. R. Dual-Responsive Enzyme–Polysaccharide Conjugate as a Nanocarrier System for Enzyme Prodrug Therapy. Biomacromolecules, 2023, 24(5), 2138–2148. doi: 10.1021/acs.biomac.3c00031
  229. Emami, F.; Duwa, R.; Banstola, A.; Woo, S. M.; Kwon, T. K.; Yook, S. Dual Receptor Specific Nanoparticles Targeting EGFR and PD-L1 for Enhanced Delivery of Docetaxel in Cancer Therapy. Biomedicine & Pharmacotherapy, 2023, 165, 115023. doi: 10.1016/j.biopha.2023.115023
  230. Chen, Y.-C.; Li, Y.; Yan, C.-C. S.; Hsu, C.-P.; Cheng, P.-L.; Tu, H.-L. DNA Tension Assays Reveal That Force-Dependent Integrin Activation Regulates Neurite Outgrowth in Primary Cortical Neurons. Biomaterials Advances, 2023, 150, 213431. doi: 10.1016/j.bioadv.2023.213431
  231. Monzó, C.; Gkioni, L.; Beyer, A.; Valenzano, D. R.; Grönke, S.; Partridge, L. Dietary Restriction Mitigates the Age-Associated Decline in Mouse B Cell Receptor Repertoire Diversity. Cell Reports, 2023, 42(7), 112722. doi: 10.1016/j.celrep.2023.112722
  232. Zabegina, L.; Zyatchin, I.; Kniazeva, M.; Shalaev, A.; Berkut, M.; Sharoyko, V.; Mikhailovskii, V.; Kondratov, K.; Reva, S.; Nosov, A.; Malek, A. Diagnosis of Prostate Cancer through the Multi-Ligand Binding of Prostate-Derived Extracellular Vesicles and MiRNA Analysis. Life, 2023, 13(4), 885. doi: 10.3390/life13040885
  233. Chu, W.; Houston, Z. H.; Fletcher, N. L.; Huda, P.; Ahamed, M.; Lim, T. X.; Day, B. W.; Pinkham, M.; Thurecht, K. J. Development and Validation of a Targeted Treatment for Brain Tumors Using a Multi-Drug Loaded, Relapse-Resistant Polymeric Theranostic. Biomacromolecules, 2023, 24(6), 2674–2690. doi: 10.1021/acs.biomac.3c00138
  234. Chetverikov, Ph.E.; Desnitskiy, A.G.; Klimov, P.B.; Ozman- Sullivan, S.K.; Romanovich, A.E.; Sukhareva, S.I. Deuterogyny and the Association of Two Vagrant Eriophyoid Mites (Acariformes, Eriophyoidea) with the Host-Plant Generative Organs of Two Broad-Leaved Trees in North-West Russia. Zoological Studies, 2023, 62, 35. doi: 10.6620/ZS.2023.62-35
  235. Sakhabutdinova, A. R.; Chemeris, A. V.; Garafutdinov, R. R. Detection of Specific RNA Targets by Multimerization. Biochemistry (Moscow), 2023, 88(5), 679–686. doi: 10.1134/S0006297923050103
  236. Seipp, E. K.; Huang, R. Design and Synthesis of a Fluorescent Probe to Develop a Fluorescence Polarization Assay for the E3 Ligase FEM1C. Bioorganic & Medicinal Chemistry, 2023, 90, 117371. doi: 10.1016/j.bmc.2023.117371
  237. Lawanprasert, A.; Sloand, J. N.; González Vargas, M.; Singh, H.; Eldor, T.; Miller, M. A.; Pimcharoen, S.; Wang, J.; Leighow, S. M.; Pritchard, J. R.; Dokholyan, N. V.; Medina, S. H. Deciphering the Mechanistic Basis for Perfluoroalkyl-Protein Interactions. ChemBioChem, 2023, 24(13), e202300159. doi: 10.1002/cbic.202300159
  238. Feigin, C. Y.; Moreno, J. A.; Ramos, R.; Mereby, S. A.; Alivisatos, A.; Wang, W.; Van Amerongen, R.; Camacho, J.; Rasweiler, J. J.; Behringer, R. R.; Ostrow, B.; Plikus, M. V.; Mallarino, R. Convergent Deployment of Ancestral Functions during the Evolution of Mammalian Flight Membranes. Sci Adv, 2023, 9(12), eade7511. doi: 10.1126/sciadv.ade7511
  239. Zhang, Q.; Li, X.; Huang, K.; Huang, Y.; Zhao, S.; Liu, S.; Li, Y. Controlling the Trimerization of the Collagen Triple-Helix by Solvent Switching. Biomacromolecules, 2023, 24(4), 1689–1699. doi: 10.1021/acs.biomac.2c01475
  240. Mazrad, Z. A. I.; Leiske, M. N.; Tabor, R. F.; Nicolazzo, J. A.; Kempe, K. Comparison of the Anti-Inflammatory Activity and Cellular Interaction of Brush Polymer–N-Acetyl Cysteine Conjugates in Human and Murine Microglial Cell Lines. Mol. Pharmaceutics, 2023, 20(5), 2686–2701. doi: 10.1021/acs.molpharmaceut.3c00140
  241. Svinko, V. O.; Smirnov, A. N.; Shevchuk, A. I.; Demenshin, A. I.; Smirnov, A. A.; Solovyeva, E. V. Comparative Study of Fluorescence Core-Shell Nanotags with Different Morphology of Gold Core. Colloids and Surfaces B: Biointerfaces, 2023, 226, 113306. doi: 10.1016/j.colsurfb.2023.113306
  242. Abil, Z.; Restrepo Sierra, A. M.; Danelon, C. Clonal Amplification-Enhanced Gene Expression in Synthetic Vesicles. ACS Synth Biol, 2023, 12(4), 1187–1203. doi: 10.1021/acssynbio.2c00668
  243. Hostert, J.D.; Sepesy, M. R.; Duval, C. E.;  Renner, J.N. Clickable Polymer Scaffolds Enable Ce Recovery with Peptide Ligands. Soft Matter, 2023, 19(15), 2823–2831. doi: 10.1039/D2SM01664H
  244. Farkas, S.; Cioca, D.; Murányi, J.; Hornyák, P.; Brunyánszki, A.; Szekér, P.; Boros, E.; Horváth, P.; Hujber, Z.; Rácz, G. Z.; Nagy, N.; Tóth, R.; Nyitray, L.; Péterfi, Z. Chlorotoxin Binds to Both Matrix Metalloproteinase 2 and Neuropilin 1. Journal of Biological Chemistry, 2023, 299(9), 104998. doi: 10.1016/j.jbc.2023.104998
  245. Crothers, R. A.; Orr, N. H. P.; van der Meer, B.; Dullens, R. P. A.; Yanagishima, T. Characterization and Optimization of Fluorescent Organosilica Colloids for 3D Confocal Microscopy Prepared Under “Zero-Flow” Conditions. Langmuir, 2023, 39(15), 5306–5314. doi: 10.1021/acs.langmuir.2c03306
  246. Kozlova, T.; Popov, A.; Romanov, M. V.; Savintseva, I.; Vasilyeva, D. N.; Baranchikov, A.; Ivanov, V. Ceric Phosphates and Nanocrystalline Ceria: Selective Toxicity to Melanoma Cells. Nanosystems: Physics, Chemistry, Mathematics, 2023, 14, 223–230. doi: 10.17586/2220-8054-2023-14-2-223-230
  247. Bianchi, A.; De Castro Silva, I.; Deshpande, N. U.; Singh, S.; Mehra, S.; Garrido, V. T.; Guo, X.; Nivelo, L. A.; Kolonias, D. S.; Saigh, S. J.; Wieder, E.; Rafie, C. I.; Dosch, A. R.; Zhou, Z.; Umland, O.; Amirian, H.; Ogobuiro, I. C.; Zhang, J.; Ban, Y.; Shiau, C.; Nagathihalli, N. S.; Montgomery, E. A.; Hwang, W. L.; Brambilla, R.; Komanduri, K.; Villarino, A. V.; Toska, E.; Stanger, B. Z.; Gabrilovich, D. I.; Merchant, N. B.; Datta, J. Cell-Autonomous Cxcl1 Sustains Tolerogenic Circuitries and Stromal Inflammation via Neutrophil-Derived TNF in Pancreatic Cancer. Cancer Discovery, 2023, 13(6), 1428–1453. doi: 10.1158/2159-8290.CD-22-1046
  248. Chang, Y.; Cai, X.; Syahirah, R.; Yao, Y.; Xu, Y.; Jin, G.; Bhute, V. J.; Torregrosa-Allen, S.; Elzey, B. D.; Won, Y.-Y.; Deng, Q.; Lian, X. L.; Wang, X.; Eniola-Adefeso, O.; Bao, X. CAR-Neutrophil Mediated Delivery of Tumor-Microenvironment Responsive Nanodrugs for Glioblastoma Chemo-Immunotherapy. Nature Communications, 2023, 14(1), 2266. doi: 10.1038/s41467-023-37872-4
  249. Wang, H.; Lee, D.; Cao, Y.; Bi, X.; Du, J.; Miao, K.; Wei, L. Bond-Selective Fluorescence Imaging with Single-Molecule Sensitivity. Nature Photonics, 2023, 17(10), 846–855. doi: 10.1038/s41566-023-01243-8
  250. Li, H.; Bruce, G.; Childerhouse, N.; Keegan, G.; Mantovani, G.; Stolnik, S. Biotin Receptor-Mediated Intracellular Delivery of Synthetic Polypeptide-Protein Complexes. Journal of Controlled Release, 2023, 357, 333–341. doi: 10.1016/j.jconrel.2023.03.051
  251. Ivanov, A. V.; Safenkova, I. V.; Zherdev, A. V.; Wan, Y.; Dzantiev, B. B. Comparison of Single-Stranded DNA Probes Conjugated with Magnetic Particles for Trans-Cleavage in Cas12a-Based Biosensors. Biosensors, 2023, 23(7), 700. doi: 10.3390/bios13070700
  252. Rodgers, M. L.; Sun, Y.; Woodson, S. A. Ribosomal Protein S12 Hastens Nucleation of Co-Transcriptional Ribosome Assembly. Biomolecules, 2023, 13(6), 951. doi: 10.3390/biom13060951
  253. Xie, Y.; Ye, J.; Ouyang, Y.; Gong, J.; Li, C.; Deng, Y.; Mai, Y.; Liu, Y.; Deng, W. Microneedle-Assisted Topical Delivery of Idebenone-Loaded Bioadhesive Nanoparticles Protect against UV-Induced Skin Damage. Biomedicines, 2023, 11(6), 1649. doi: 10.3390/biomedicines11061649
  254. Herman, C. E.; Min, L.; Choe, L. H.; Maurer, R. W.; Xu, X.; Ghose, S.; Lee, K. H.; Lenhoff, A. M. Behavior of Host-Cell-Protein-Rich Aggregates in Antibody Capture and Polishing Chromatography. Journal of Chromatography A, 2023, 1702, 464081. doi: 10.1016/j.chroma.2023.464081
  255. Liu, N.; Gujrati, V.; Werner, J. P. F.; Mishra, K.; Anzenhofer, P.; Stiel, A. C.; Mettenleiter, G.; Feuchtinger, A.; Walch, A.; Ntziachristos, V. Bacterial Outer Membrane Vesicles as Cationic Dye Carriers for Optoacoustics-Guided Phototherapy of Cancer. Cancer Nanotechnology, 2023, 14(1), 36. doi: 10.1186/s12645-023-00191-w
  256. Hernández‐Carralero, E.; Cabrera, E.; Rodríguez-Torres, G.; Hernández-Reyes, Y.; Singh, A. N.; Santa-María, C.; Fernández-Justel, J. M.; Janssens, R. C.; Marteijn, J. A.; Evert, B. O.; Mailand, N.; Gómez, M.; Ramadan, K.; Smits, V. A. J.; Freire, R. ATXN3 Controls DNA Replication and Transcription by Regulating Chromatin Structure. Nucleic Acids Research, 2023, 51(11), 5396–5413. doi: 10.1093/nar/gkad212
  257. Wang, D.; Li, Y.; Deng, X.; Torre, M.; Zhang, Z.; Li, X.; Zhang, W.; Cullion, K.; Kohane, D. S.; Weldon, C. B. An Aptamer-Based Depot System for Sustained Release of Small Molecule Therapeutics. Nature Communications, 2023, 14(1), 2444. doi: 10.1038/s41467-023-37002-0
  258. Xue, X.; Qu, H.; Bo, R.; Zhang, D.; Zhu, Z.; Xiang, B.; Li, L.; Ricci, M.; Pan, C.-X.; Lin, T.-Y.; Li, Y. A Transformable Nanoplatform with Multiple Therapeutic and Immunostimulatory Properties for Treatment of Advanced Cancers. Biomaterials, 2023, 299, 122145. doi: 10.1016/j.biomaterials.2023.122145
  259. Yang, Z.; Xie, H.; Wan, J.; Wang, Y.; Zhang, L.; Zhou, K.; Tang, H.; Zhao, W.; Wang, H.; Song, P.; Zheng, S. A Nanotherapeutic Strategy That Engages Cytotoxic and Immunosuppressive Activities for the Treatment of Cancer Recurrence Following Organ Transplantation. eBioMedicine, 2023, 92, 104594. doi: 10.1016/j.ebiom.2023.104594
  260. Yoshikawa, A. M.; Rangel, A. E.; Zheng, L.; Wan, L.; Hein, L. A.; Hariri, A. A.; Eisenstein, M.; Soh, H. T. A Massively Parallel Screening Platform for Converting Aptamers into Molecular Switches. Nat Commun, 2023, 14(1), 2336. doi: 10.1038/s41467-023-38105-4
  261. De Rosa, L.; Hawala, I.; Di Stasi, R.; Stefania, R.; Capozza, M.; Nava, D.; D’Andrea, L. D. A Chemical Strategy for the Preparation of Multimodified Peptide Imaging Probes. J Org Chem, 2023, 88(7), 4546–4553. doi: 10.1021/acs.joc.3c00014
  262. Hull, S. M.; Lou, J.; Lindsay, C. D.; Navarro, R. S.; Cai, B.; Brunel, L. G.; Westerfield, A. D.; Xia, Y.; Heilshorn, S. C. 3D Bioprinting of Dynamic Hydrogel Bioinks Enabled by Small Molecule Modulators. Sci Adv, 2023, 9(13), eade7880. doi: 10.1126/sciadv.ade7880
  263. Tsai, H.-Y.; Robidillo, C. J. T.; Matharu, G. K.; O’Connor, K.; Cheong, I. T.; Ni, C.; Veinot, J. G. C.; Algar, W. R. Spectrotemporal Characterization of Photoluminescent Silicon Nanocrystals and Their Energy Transfer to Dyes. Nanoscale, 2023, 15(30), 12492–12505. doi: 10.1039/D3NR02461J
  264. Robertus, C. M.; Snyder, S. M.; Curley, S. M.; Murundi, S. D.; Whitman, M. A.; Fischbach, C.; Putnam, D. Selective Accumulation of Near Infrared-Labeled Multivalent Quinidine Copolymers in Tumors Overexpressing P-Glycoprotein: Potential for Noninvasive Diagnostic Imaging. ACS Appl Bio Mater, 2023, 6(8), 3117–3130. doi: 10.1021/acsabm.3c00239
  265. Ozharovskaia, T. A.; Popova, O.;Zubkova, O. V.; Vavilova, I. V.; Pochtovyy, A. A.; Shcheblyakov, D. V.; Gushchin, V.A.; Logunov, D.Yu.; Gintsburg, A.L. Development and characterization of a vector system based on the simian adenovirus type 25. Bulletin of RSMU, 2023, 1, 4-11. doi: 10.24075/brsmu.2023.006
  266. Sivolapova, A. B.; Polivanova, O. B.; Goryunov, D. V.; Chebanova, Y. V.; Fedorova, A. V.; Sotnikova, E. A.; Karabitsina, Y. I.; Benko, N. I.; Mukhina, Z. M.; Anisimova, I. N.; Demurin, Y. N.; Goryunova, S. V. Refinement of Rf1-Gene Localization and Development of the New Molecular Markers for Fertility Restoration in Sunflower. Mol Biol Rep, 2023, 50(9), 7919–7926. doi: 10.1007/s11033-023-08646-4
  267. Grinberg, I.; Ben-Zvi, O.; Adler-Abramovich, L.; Yacoby, I. Peptide Self-Assembly as a Strategy for Facile Immobilization of Redox Enzymes on Carbon Electrodes. Carbon Energy, 2023, e411. doi: 10.1002/cey2.411
  268. Pattadar, D.; Arcidiacono, A.; Beery, D.; Hanson, K.; Saavedra, S. S. Molecular Orientation and Energy Transfer Dynamics of a Metal Oxide Bound Self-Assembled Trilayer. Langmuir, 2023, 39(30), 10670–10679. doi: 10.1021/acs.langmuir.3c01323
  269. Makam, S.; Sétamou, M.; Alabi, O. J.; Day, W.; Cromey, D.; Nwugo, C. Mitigation of Huanglongbing: Implications of a Biologically-Enhanced Nutritional Program on Yield, Pathogen Localization and Host Gene Expression Profiles. Plant Disease, 2023. doi: 10.1094/PDIS-10-22-2336-RE
  270. Peng, Y.-J.; Nanduri, J.; , Wang, N.; Kumar, G.K.; Bindokas, V.;,Paul, B.D.; Chen, X.; Fox, A.P.; Vignane, T.; Filipovic, M.R.; Prabhakar, N.R. Hypoxia sensing requires H2S-dependent persulfidation of olfactory receptor 78. Science Advances, 2023, 9(27), eadf302. doi: 10.1126/sciadv.adf3026
  271. Liang, C.; Huang, W.; Zhang, Y.; Zhang, D.; An, S.; Wu, Q.; Zhao, H.; Wang, C.; Huang, G.; Wei, W.; Liu, J. ImmunoPET Imaging of CD47 with VHH-Derived Tracers in Pancreatic Cancers. Mol. Pharmaceutics, 2023, 20(8), 4184–4195. doi: 10.1021/acs.molpharmaceut.3c00311
  272. Cheng, C.; Zhang, J.; Liu, K.; Xu, Y.; Shen, F.; Han, Y.; Hou, Y.; Zhang, T.; Bai, G. Ginsenoside CK Targeting KEAP1-DGR/Kelch Domain Disrupts the Binding between KEAP1 and NRF2-DLG Motif to Ameliorate Oxidative Stress Damage. Phytomedicine, 2023, 119, 154992. doi: 10.1016/j.phymed.2023.154992
  273. Mauser, A.; Quevedo, D. F.; Zhang, B.; Hernandez, Y.; Berardi, A.; Brown, W.; Lee, S.; Miki, R.; Raymond, J.; Lahann, J.; Greineder, C. F. . Enzyme-Based Synthetic Protein Nanoparticles as Colloidal Antioxidants, 2023, 2300007. doi: 10.1002/adtp.202300007
  274. De Pauw, E.; Chen, Y.; De Keersmaecker, H.; De Coninck, E.; De Smet, L.; De Geest, B.; Braeckmans, K.; Vervaet, C.; Vanhoorne, V. Drying Behaviour and Visualization of Surfactants after Co-Spray Drying of Surfactant-Stabilized Aqueous Suspensions. International Journal of Pharmaceutics, 2023, 643, 123231. doi: 10.1016/j.ijpharm.2023.123231
  275. Borner, T.; Tinsley, I. C.; Milliken, B. T.; Doebley, S. A.; Najjar, N. R.; Kerwood, D. J.; De Jonghe, B. C.; Hayes, M. R.; Doyle, R. P. Creation of a Peptide Antagonist of the GFRAL–RET Receptor Complex for the Treatment of GDF15-Induced Malaise. J. Med. Chem., 2023, 66(16), 11237–11249. doi: 10.1021/acs.jmedchem.3c00667
  276. Hu, H.-Y.; Deng, J.-Q.; Wang, Y.-J.; Li, Y.; Meng, X.-L.; Jiang, W.-J.; Wang, F.-S.; Sheng, J.-Z. Cell-Based Assay Approaches for Glycosaminoglycan Synthase High-Throughput Screening: Development and Applications. ACS Chem Biol, 2023, 18(7), 1632–1641. doi: 10.1021/acschembio.3c00244
  277. Breine, A.; Van holsbeeck, K.; Martin, C.; Gonzalez, S.; Mannes, M.; Pardon, E.; Steyaert, J.; Remaut, H.; Ballet, S.; Van der Henst, C. Bypassing the Need for Cell Permeabilization: Nanobody CDR3 Peptide Improves Binding on Living Bacteria. Bioconjugate Chem, 2023, 34(7), 1234–1243. doi: 10.1021/acs.bioconjchem.3c00116
  278. Dai, C.-Y.; Ng, C. C.; Hung, G. C. C.; Kirmes, I.; Hughes, L. A.; Du, Y.; Brosnan, C. A.; Ahier, A.; Hahn, A.; Haynes, C. M.; Rackham, O.; Filipovska, A.; Zuryn, S. ATFS-1 Counteracts Mitochondrial DNA Damage by Promoting Repair over Transcription. Nat Cell Biol, 2023, 25, 1111-1120. doi: 10.1038/s41556-023-01192-y
  279. Rwandamuriye, F. X.; Evans, C. W.; Wylie, B.; Norret, M.; Vitali, B.; Ho, D.; Nguyen, D.; Roper, E. A.; Wang, T.; Hepburn, M. S.; Sanderson, R. W.; Pfirrmann, M.; Fear, V. S.; Forbes, C. A.; Wyatt, K.; Ryan, A. L.; Johns, T. G.; Phillips, M. B.; Hodder, R.; Leslie, C.; Kennedy, B. F.; Zemek, R. M.; Iyer, K. S.; Lesterhuis, W. J. A Surgically Optimized Intraoperative Poly(I:C)-Releasing Hydrogel Prevents Cancer Recurrence. CR Med, 2023, 4(7). doi: 10.1016/j.xcrm.2023.101113
  280. Yang, C., Xu, H., Yang, D.; Xie, Y.; Xiong, M.; Fan, Y.; Liu, X.; Zhang, Y.; Xiao, Y.; Chen, Y.; Zhou, Y.; Song, L.; Wang, C.; Peng, A.; Petersen, R.B.; Chen, H.; Zheng, L.;. A renal YY1-KIM1-DR5 axis regulates the progression of acute kidney injury. Nat Commun, 2023, 14(1), 4261. doi: 10.1038/s41467-023-40036-z
  281. Hossain, K.; Smith, M.; Santoro, S.W. A histological protocol for quantifying the birthrates of specific subtypes of olfactory sensory neurons in mice. STAR Protocols, 2023, 4(3), 102432. doi: 10.1016/j.xpro.2023.102432
  282. Grohme, M.; Frank, O.; Rink, J. Preparing Planarian Cells for High-content Fluorescence Microscopy Using RNA in situ Hybridization and Immunocytochemistry. Methods in Molecular Biology, 2023, 2680, 121-155. doi: 10.1007/978-1-0716-3275-8_8
  283. Amelchenko, E.M.; Bezriadnov, D.V.; Chekhov, O.A.; Ivanova, A.A.; Kedrov, A.V.; Anokhin, K.V.; Lazutkin, A.A.; Enikolopov, G. Cognitive Flexibility Is Selectively Impaired by Radiation and Is Associated with Differential Recruitment of Adult-Born Neurons. The Journal of Neuroscience, 2023, 43(34), 6061-6083. doi: 10.1523/JNEUROSCI.0161-22.2023
  284. Tolmacheva, I.; Beloglazova, Y.; Nazarov, M.; Gagarskikh, O.; Grishko, V. Synthesis and Anticancer Activity of A-Ring-Modified Derivatives of Dihydrobetulin. International Journal of Molecular Sciences, 2023, 24(12), 9863. doi: 10.3390/ijms24129863
  285. Shik, A.V.; Stepanova, I.A.; Doroshenko, I.A.; Podrugina, T.A.; Beklemishev, M.K. Carbocyanine-Based Optical Sensor Array for the Discrimination of Proteins and Rennet Samples Using Hypochlorite Oxidation. Sensors (Basel), 2023, 23(9), 4299. doi: 10.3390/s23094299
  286. Girich, E.V.; Trinh, P.T.H; Nesterenko, L.E.; Popov, R.S.; Kim, N.Y.; Rasin, A.B.; Menchinskaya, E.S.; Kuzmich, A.S.; Chingizova, E.A.; Minin, A.S.; Ngoc, N.T.D.; Van, T.T.T.; Yurchenko, E.A.; Yurchenko, A.N.; Berdyshev, D.V. Absolute Stereochemistry and Cytotoxic Effects of Vismione E from Marine Sponge-Derived Fungus Aspergillus sp. 1901NT-1.2.2. International Journal of Molecular Sciences, 2023, 24(9), 8150. doi: 10.3390/ijms24098150
  287. Gileva, A.; Trushina, D.; Yagolovich, A.; Gasparian, M.; Kurbanova, L.; Smirnov, I.; Burov, S.; Markvicheva, E. Doxorubicin-Loaded Polyelectrolyte Multilayer Capsules Modified with Antitumor DR5-Specific TRAIL Variant for Targeted Drug Delivery to Tumor Cells. Nanomaterials, 2023, 13(5), 902. doi: 10.3390/nano13050902
  288. Psotta, C.; Chaturvedi, V.; Gonzalez-Martinez, J.F.; Sotres, J.; Falk, M. Portable Prussian Blue-Based Sensor for Bacterial Detection in Urine. Sensors, 2023, 23(1), 388. doi: 10.3390/s23010388
  289. Pypin, A.A.; Shik, A.V.; Stepanova, I.A.; Doroshenko, I.A.; Podrugina, T.A.; Beklemishev, M.K. A Reaction-Based Optical Fingerprinting Strategy for the Recognition of Fat-Soluble Samples: Discrimination of Motor Oils. Sensors, 2023, 23(18), 7682. doi: 10.3390/s23187682
  290. Maltsev, D.I.; Aniol, V.A.; Golden, M.A.; Petrina, A.D.; Belousov, V.V.; Gulyaeva, N.V.; Podgorny, O.V. Aging Modulates the Ability of Quiescent Radial Glia-Like Stem Cells in the Hippocampal Dentate Gyrus to be Recruited into Division by Pro-neurogenic Stimuli. Molecular Neurobiology, 2023. doi: 10.1007/s12035-023-03746-5
  291. Feng, Y.; Lee, J.; Yang, L.; Hilton, M.B.; Morris, K.; Seaman, S.; Edupuganti, V.V.S.R.; Hsu, K.-S.; Dower, C.; Yu, G.; So, D.; Bajgain, P.; Zhu, Z.; Dimitrov, D.S.; Patel, N.L.; Robinson, C.M.; Difilippantonio, S.; Dyba, M.; Corbel, A.; Basuli, F.; Swenson, R.E.; Kalen, J.D.; Suthe, S.R.; Hussain, M.; Italia, J.S.; Souders, C.A.; Gao, L.; Schnermann, M.J.; St. Croix, B. Engineering CD276/B7-H3-targeted antibody-drug conjugates with enhanced cancer-eradicating capability. Cell Reports, 2023, 42(12), 113503. doi: 10.1016/j.celrep.2023.113503
  292. Yang, Z.; Yao, Q.; Gong, L.; Zhang, F.; Sun, J.; Sun, Y.; Gao, W. A Superlong‐acting Growth Hormone‐polypeptide Fusion for Growth Hormone Deficiency Treatment. Advanced Healthcare Materials, 2023, 2302507. doi: 10.1002/adhm.202302507
  293. Jaiswal, R.K.; Lei, K.-H.; Chastain, M.; Wang, Y.; Shiva, O.; Li, S.; You, Z.; Chi, P.; Chai, W. CaMKK2 and CHK1 phosphorylate human STN1 in response to replication stress to protect stalled forks from aberrant resection. Nature Communications, 2023, 14(1), 7882. doi: 10.1038/s41467-023-43685-2
  294. Gantsova, E.A.; Serova, O.V.; Eladari, D.; Bobrovskiy, D.M.; Petrenko, A.G.; Elchaninov, A.V.; Deyev, I.E. A Comparative Kidney Transcriptome Analysis of Bicarbonate-Loaded insrr-Null Mice. Current Issues in Molecular Biology, 2023, 45(12), 9709-9722. doi: 10.3390/cimb45120606
  295. Situngu, S.; Elhalawany, A.S.; Ngubane-Ndhlovu, N.P.; Chetverikov, P.E. New species and records of gall mites of the genus Aceria (Eriophyoidea, Eriophyidae) associated with Tamarix in Egypt and South Africa. Acarologia, 2023, 63(4), 1271-1303. doi: 10.24349/n4ay-b8yb
  296. Jatzlau, J.; Burdzinski, W.; Trumpp, M.; Obendorf, L.; Roßmann, K.; Ravn, K.; Hyvönen, M.; Bottanelli, F.; Broichhagen, J.; Knaus, P. A versatile Halo- and SNAP-tagged BMP/TGFβ receptor library for quantification of cell surface ligand binding. Communications Biology, 2023, 6, 34. doi: 10.1038/s42003-022-04388-4
  297. Nikulin, S.; Razumovskaya, A.; Poloznikov, A.; Zakharova, G.; Alekseev, B.; Tonevitsky, A. ELOVL5 and IGFBP6 genes modulate sensitivity of breast cancer cells to ferroptosis. Frontiers in Molecular Biosciences, 2023, 10, 1075704. doi: 10.3389/fmolb.2023.1075704
  298. Mitin, D.E.; Chubarov, A.S. Fluorinated Human Serum Albumin as Potential 19 F Magnetic Resonance Imaging Probe. Molecules, 2023, 28(4), 1695. doi: 10.3390/molecules28041695
  299. Murar, M.; Pujals, S.; Albertazzi, L. Multivalent effect of peptide functionalized polymeric nanoparticles towards selective prostate cancer targeting † † Electronic supplementary information (ESI) available. See DOI: https://doi.org/10.1039/d2na00601d. Nanoscale Advances, 2023, 5, 1378-1385. doi: 10.1039/d2na00601d
  300. Liu, H.; Shima, T. Preference of CAMSAP3 for expanded microtubule lattice contributes to stabilization of the minus end. Life Science Alliance, 2023, 6(5), e202201714. doi: 10.26508/lsa.202201714
  301. Birnbaum, L.A.; Sullivan, E.C.; Do, P.; Uricoli, B.; Raikar, S.S.; Porter, C.C.; Henry, C.J.; Dreaden, E.C. Multicolor Light-Induced Immune Activation via Polymer Photocaged Cytokines. Biomacromolecules, 2023, 24(3), 1164-1172. doi: 10.1021/acs.biomac.2c01207
  302. Yang, W.; Miyazaki, T.; Nakagawa, Y.; Boonstra, E.; Masuda, K.; Nakashima, Y.; Chen, P.; Mixich, L.; Barthelmes, K.; Matsumoto, A.; Mi, P.; Uchida, S.; Cabral, H. Block catiomers with flanking hydrolyzable tyrosinate groups enhance in vivo mRNA delivery via π–π stacking-assisted micellar assembly. Science and Technology of Advanced Materials, 2023, 24(1), 2170164. doi: 10.1080/14686996.2023.2170164
  303. Palange, A.L.; Mascolo, D.D.; Ferreira, M.; Gawne, P.J.; Spanò, R.; Felici, A.; Bono, L.; Moore, T.L.; Salerno, M.; Armirotti, A.; Decuzzi, P. Boosting the Potential of Chemotherapy in Advanced Breast Cancer Lung Metastasis via Micro‐Combinatorial Hydrogel Particles. Advanced Science, 2023, 10(10), 2205223. doi: 10.1002/advs.202205223
  304. Fischbach, A.; Johns, A.; Schneider, K.L.; Hao, X.; Tessarz, P.; Nyström, T. Artificial Hsp104-mediated systems for re-localizing protein aggregates. Nature Communications, 2023, 14, 2663. doi: 10.1038/s41467-023-37706-3
  305. Ren, J.; Zhou, H.; Zeng, H.; Wang, C.K.; Huang, J.; Qiu, X.; Sui, X.; Li, Q.; Wu, X.; Lin, Z.; Lo, J.A.; Maher, K.; He, Y.; Tang, X.; Lam, J.; Chen, H.; Li, B.; Fisher, D.E.; Liu, J.; Wang, X. Spatiotemporally resolved transcriptomics reveals the subcellular RNA kinetic landscape. Nature Methods, 2023, 20, 695-705. doi: 10.1038/s41592-023-01829-8
  306. Kladova, O.A.; Tyugashev, T.E.; Mikushina, E.S.; Kuznetsov, N.A.; Novopashina, D.S.; Kuznetsova, A.A. The Activity of Natural Polymorphic Variants of Human DNA Polymerase β Having an Amino Acid Substitution in the Transferase Domain. Cells, 2023, 12(9), 1300. doi: 10.3390/cells12091300
  307. Kolganova, N.A.; Tsvetkov, V.B.; Stomakhin, A.A.; Surzhikov, S.A.; Timofeev, E.N.; Varizhuk, I.V. Alpha-Deoxyguanosine to Reshape the Alpha-Thrombin Binding Aptamer. International Journal of Molecular Sciences, 2023, 24(9), 8406. doi: 10.3390/ijms24098406
  308. Lee, S.; Kim, D.; Kang, K.-K.; Sung, S.-E.; Choi, J.-H.; Sung, M.; Shin, C.-H.; Jeon, E.; Kim, D.; Kim, D.; Lee, S.; Kim, H.-K.; Kim, K. Toxicity and Biodistribution of Fragmented Polypropylene Microplastics in ICR Mice. International Journal of Molecular Sciences, 2023, 24(10), 8463. doi: 10.3390/ijms24108463
  309. Hildebrandt, R.P.; Moss, K.R.; Janusz-Kaminska, A.; Knudson, L.A.; Denes, L.T.; Saxena, T.; Boggupalli, D.P.; Li, Z.; Lin, K.; Bassell, G.J.; Wang, E.T. Muscleblind-like proteins use modular domains to localize RNAs by riding kinesins and docking to membranes. Nature Communications, 2023, 14, 3427. doi: 10.1038/s41467-023-38923-6
  310. Shlosman, I.; Fivenson, E.M.; Gilman, M.S.A.; Sisley, T.A.; Walker, S.; Bernhardt, T.G.; Kruse, A.C.; Loparo, J.J. Allosteric activation of cell wall synthesis during bacterial growth. Nature Communications, 2023, 14, 3439. doi: 10.1038/s41467-023-39037-9
  311. Dave, P.; Roth, G.; Griesbach, E.; Mateju, D.; Hochstoeger, T.; Chao, J.A. Single-molecule imaging reveals translation-dependent destabilization of mRNAs. Molecular Cell, 2023, 83(4), 589-606.e6. doi: 10.1016/j.molcel.2023.01.013
  312. Navalón-López, M.; Dols-Perez, A.; Grijalvo, S.; Fornaguera, C.; Borrós, S. Unravelling the role of individual components in pBAE/polynucleotide polyplexes in the synthesis of tailored carriers for specific applications: on the road to rational formulations. Nanoscale Advances, 2023, 5(6), 1611-1623. doi: 10.1039/d2na00800a
  313. Sun, R.; Zhao, Y.; Wang, W.; Liu, J.-J.G.; Chen, C. Nonspecific interactions between Cas12a and dsDNA located downstream of the PAM mediate target search and assist AsCas12a for DNA cleavage. Chemical Science, 2023, 14(14), 3839-3851. doi: 10.1039/d2sc05463a
  314. Shah, A.M.; Guo, L.; Morales, M.G.; Jaichander, P.; Chen, K.; Huang, H.; Cano Hernandez, K.; Xu, L.; Bassel-Duby, R.; Olson, E.N.; Liu, N. TWIST2-mediated chromatin remodeling promotes fusion-negative rhabdomyosarcoma. Science Advances, 2023, 9(17), eade8184. doi: 10.1126/sciadv.ade8184
  315. Sajeesh, S.; Camardo, A.; Dahal, S.; Ramamurthi, A. Surface-Functionalized Stem Cell-Derived Extracellular Vesicles for Vascular Elastic Matrix Regenerative Repair. Molecular Pharmaceutics, 2023, 20(6), 2801-2813. doi: 10.1021/acs.molpharmaceut.2c00769
  316. Kalashnikova, I.; Cambell, H.; Kolpek, D.; Park, J. Optimization and characterization of miRNA-129-5p-encapsulated poly (lactic- co -glycolic acid) nanoparticles to reprogram activated microglia. Nanoscale Advances, 2023, 5(13), 3439-3452. doi: 10.1039/d3na00149k
  317. Daumar, P.; Goisnard, A.; Dubois, C.; Roux, M.; Depresle, M.; Penault-Llorca, F.; Bamdad, M.; Mounetou, E. Chemical biology fluorescent tools for in vitro investigation of the multidrug resistant P-glycoprotein (P-gp) expression in tumor cells. RSC Advances, 2023, 13(39), 27016-27035. doi: 10.1039/d3ra05093a
  318. Musicò, A.; Zenatelli, R.; Romano, M.; Zendrini, A.; Alacqua, S.; Tassoni, S.; Paolini, L.; Urbinati, C.; Rusnati, M.; Bergese, P.; Pomarico, G.; Radeghieri, A. Surface functionalization of extracellular vesicle nanoparticles with antibodies: a first study on the protein corona “variable” † † Electronic supplementary information (ESI) available. See DOI: https://doi.org/10.1039/d3na00280b. Nanoscale Advances, 2023, 5(18), 4703-4717. doi: 10.1039/d3na00280b
  319. Yang, Y.; Hu, R.; Zheng, J.; Wang, Q.; Xu, S.; Zhou, Z.; Zhang, D.; Shen, W. Glucocorticoid nanoformulations relieve chronic pelvic pain syndrome and may alleviate depression in mice. Journal of Nanobiotechnology, 2023, 21, 198. doi: 10.1186/s12951-023-01893-4
  320. Aitova, A.; Scherbina, S.; Berezhnoy, A.; Slotvitsky, M.; Tsvelaya, V.; Sergeeva, T.; Turchaninova, E.; Rybkina, E.; Bakumenko, S.; Sidorov, I.; Popov, M.A.; Dontsov, V.; Agafonov, E.G.; Efimov, A.E.; Agapov, I.; Zybin, D.; Shumakov, D.; Agladze, K. Novel Molecular Vehicle-Based Approach for Cardiac Cell Transplantation Leads to Rapid Electromechanical Graft–Host Coupling. International Journal of Molecular Sciences, 2023, 24(12), 10406. doi: 10.3390/ijms241210406
  321. Nakagawa, Y.; Ushidome, K.; Masuda, K.; Igarashi, K.; Matsumoto, Y.; Yamasoba, T.; Anraku, Y.; Takai, M.; Cabral, H. Multi-Armed Star-Shaped Block Copolymers of Poly(ethylene glycol)-Poly(furfuryl glycidol) as Long Circulating Nanocarriers. Polymers, 2023, 15(12), 2626. doi: 10.3390/polym15122626
  322. Kubota, T.; Takahashi, S.; Yamamoto, R.; Sato, R.; Miyanooto, A.; Yamamoto, R.; Yamauchi, K.; Homma, K.; Takahashi, M.P. Optical measurement of gating pore currents in hypokalemic periodic paralysis model cells. Disease Models & Mechanisms, 2023, 16(6), dmm049704. doi: 10.1242/dmm.049704
  323. Mochalova, E.N.; Egorova, E.A.; Komarova, K.S.; Shipunova, V.O.; Khabibullina, N.F.; Nikitin, P.I.; Nikitin, M.P. Comparative Study of Nanoparticle Blood Circulation after Forced Clearance of Own Erythrocytes (Mononuclear Phagocyte System-Cytoblockade) or Administration of Cytotoxic Doxorubicin- or Clodronate-Loaded Liposomes. International Journal of Molecular Sciences, 2023, 24(13), 10623. doi: 10.3390/ijms241310623
  324. Slapak, E.J.; el Mandili, M.; Brink, M.S.T.; Kros, A.; Bijlsma, M.F.; Spek, C.A. Preclinical Assessment of ADAM9-Responsive Mesoporous Silica Nanoparticles for the Treatment of Pancreatic Cancer. International Journal of Molecular Sciences, 2023, 24(13), 10704. doi: 10.3390/ijms241310704
  325. Silchenko, A.S.; Kalinovsky, A.I.; Avilov, S.A.; Popov, R.S.; Dmitrenok, P.S.; Chingizova, E.A.; Menchinskaya, E.S.; Panina, E.G.; Stepanov, V.G.; Kalinin, V.I.; Stonik, V.A. Djakonoviosides A, A1, A2, B1–B4 — Triterpene Monosulfated Tetra- and Pentaosides from the Sea Cucumber Cucumaria djakonovi : The First Finding of a Hemiketal Fragment in the Aglycones; Activity against Human Breast Cancer Cell Lines. International Journal of Molecular Sciences, 2023, 24(13), 11128. doi: 10.3390/ijms241311128
  326. Luo, T.; Jiang, M.; Cheng, Z.; Lin, Y.; Chen, Y.; Zhang, Z.; Zhou, J.; Zhou, W.; Yu, X.-F.; Li, S.; Geng, S.; Yang, H. Biodegradable FePS3 nanoplatform for efficient treatment of osteosarcoma by combination of gene and NIR-II photothermal therapy. Journal of Nanobiotechnology, 2023, 21, 224. doi: 10.1186/s12951-023-01961-9
  327. Hao, L.; Zhao, R.T.; Welch, N.L.; Tan, E.K.W.; Zhong, Q.; Harzallah, N.S.; Ngambenjawong, C.; Ko, H.; Fleming, H.E.; Sabeti, P.C.; Bhatia, S.N. CRISPR-Cas-amplified urinary biomarkers for multiplexed and portable cancer diagnostics. Nature Nanotechnology, 2023, 18, 798-807. doi: 10.1038/s41565-023-01372-9
  328. Shashkovskaya, V.S.; Vetosheva, P.I.; Shokhina, A.G.; Aparin, I.O.; Prikazchikova, T.A.; Mikaelyan, A.S.; Kotelevtsev, Y.V.; Belousov, V.V.; Zatsepin, T.S.; Abakumova, T.O. Delivery of Lipid Nanoparticles with ROS Probes for Improved Visualization of Hepatocellular Carcinoma. Biomedicines, 2023, 11(7), 1783. doi: 10.3390/biomedicines11071783
  329. Efimova, A.S.; Ustimova, M.A.; Chmelyuk, N.S.; Abakumov, M.A.; Fedorov, Y.V.; Fedorova, O.A. Specific Fluorescent Probes for Imaging DNA in Cell-Free Solution and in Mitochondria in Living Cells. Biosensors, 2023, 13(7), 734. doi: 10.3390/bios13070734
  330. Chen, H.; Zhang, Y.; Ma, X.; Zhou, B.; Liu, Z. Chemically-Modified Sepharose 6B Beads for Collection of Circulating Tumor Cells. Biomolecules, 2023, 13(7), 1071. doi: 10.3390/biom13071071
  331. Hu, P.; Armato, U.; Freddi, G.; Chiarini, A.; Dal Prà, I. Human Keratinocytes and Fibroblasts Co-Cultured on Silk Fibroin Scaffolds Exosomally Overrelease Angiogenic and Growth Factors. Cells, 2023, 12(14), 1827. doi: 10.3390/cells12141827
  332. Morozov, V.N.; Klimovich, M.A.; Shibaeva, A.V.; Klimovich, O.N.; Koshevaya, E.D.; Kolyvanova, M.A.; Kuzmin, V.A. Optical Polymorphism of Liquid–Crystalline Dispersions of DNA at High Concentrations of Crowding Polymer. International Journal of Molecular Sciences, 2023, 24(14), 11365. doi: 10.3390/ijms241411365
  333. Brück, P.; Wasser, D.; Soppa, J. Ploidy in Vibrio natriegens : Very Dynamic and Rapidly Changing Copy Numbers of Both Chromosomes. Genes, 2023, 14(7), 1437. doi: 10.3390/genes14071437
  334. Ponkshe, P.; Wang, Y.; Tan, C. Systemic Protein Delivery via Inhalable Liposomes: Formulation and Pharmacokinetics. Pharmaceutics, 2023, 15(7), 1951. doi: 10.3390/pharmaceutics15071951
  335. Phan, H.; Cavanagh, R.; Jacob, P.; Destouches, D.; Vacherot, F.; Brugnoli, B.; Howdle, S.; Taresco, V.; Couturaud, B. Synthesis of Multifunctional Polymersomes Prepared by Polymerization-Induced Self-Assembly. Polymers, 2023, 15(14), 3070. doi: 10.3390/polym15143070
  336. Huang, J.; Lin, G.; Juenke, T.; Chung, S.; Lai, N.; Zhang, T.; Zhang, T.; Zhang, M. Iron Oxide Nanoparticle-Mediated mRNA Delivery to Hard-to-Transfect Cancer Cells. Pharmaceutics, 2023, 15(7), 1946. doi: 10.3390/pharmaceutics15071946
  337. Han, S.; Wang, J.T.-W.; Yavuz, E.; Zam, A.; Rouatbi, N.; Utami, R.N.; Liam-Or, R.; Griffiths, A.; Dickson, W.; Sosabowski, J.; Al-Jamal, K.T. Spatiotemporal tracking of gold nanorods after intranasal administration for brain targeting. Journal of controlled release : official journal of the Controlled Release Society, 2023, 357, 606-619. doi: 10.1016/j.jconrel.2023.04.022
  338. Das, S.K.; Huynh, M.T.; Lee, T.-H. Spontaneous histone exchange between nucleosomes. The Journal of Biological Chemistry, 2023, 299(8), 105037. doi: 10.1016/j.jbc.2023.105037
  339. Lau, S.Y.; Kang, M.; Hisey, C.L.; Chamley, L.W. Studying exogenous extracellular vesicle biodistribution by in vivo fluorescence microscopy. Disease Models & Mechanisms, 2023, 16(8), dmm050074. doi: 10.1242/dmm.050074
  340. Chang, Y.-C.; Lin, K.; Baxley, R.M.; Durrett, W.; Wang, L.; Stojkova, O.; Billmann, M.; Ward, H.; Myers, C.L.; Bielinsky, A.-K. RNF4 and USP7 cooperate in ubiquitin-regulated steps of DNA replication. Open Biology, 2023, 13(8), 230068. doi: 10.1098/rsob.230068
  341. Svirelis, J.; Adali, Z.; Emilsson, G.; Medin, J.; Andersson, J.; Vattikunta, R.; Hulander, M.; Järlebark, J.; Kolman, K.; Olsson, O.; Sakiyama, Y.; Lim, R.Y.H.; Dahlin, A. Stable trapping of multiple proteins at physiological conditions using nanoscale chambers with macromolecular gates. Nature Communications, 2023, 14, 5131. doi: 10.1038/s41467-023-40889-4
  342. Liu, Z.; Guo, K.; Yan, L.; Zhang, K.; Wang, Y.; Ding, X.; Zhao, N.; Xu, F.-J. Janus nanoparticles targeting extracellular polymeric substance achieve flexible elimination of drug-resistant biofilms. Nature Communications, 2023, 14, 5132. doi: 10.1038/s41467-023-40830-9
  343. Henkin, G.; Brito, C.; Thomas, C.; Surrey, T. The minus-end depolymerase KIF2A drives flux-like treadmilling of γTuRC-uncapped microtubules. The Journal of Cell Biology, 2023, 222(10), e202304020. doi: 10.1083/jcb.202304020
  344. Colvin, L.; Tu, D.; Dunlap, D.; Rios, A.; Coté, G. A Polarity-Sensitive Far-Red Fluorescent Probe for Glucose Sensing through Skin. Biosensors, 2023, 13(8), 788. doi: 10.3390/bios13080788
  345. Burkin, K.M.; Ivanov, A.V.; Zherdev, A.V.; Dzantiev, B.B.; Safenkova, I.V. A Critical Study on DNA Probes Attached to Microplate for CRISPR/Cas12 Trans-Cleavage Activity. Biosensors, 2023, 13(8), 824. doi: 10.3390/bios13080824
  346. Zhuravleva, O.I.; Chingizova, E.A.; Oleinikova, G.K.; Starnovskaya, S.S.; Antonov, A.S.; Kirichuk, N.N.; Menshov, A.S.; Popov, R.S.; Kim, N.Y..; Berdyshev, D.V.; Chingizov, A.R.; Kuzmich, A.S.; Guzhova, I.V.; Yurchenko, A.N.; Yurchenko, E.A. Anthraquinone Derivatives and Other Aromatic Compounds from Marine Fungus Asteromyces cruciatus KMM 4696 and Their Effects against Staphylococcus aureus. Marine Drugs, 2023, 21(8), 431. doi: 10.3390/md21080431
  347. Vesnina, A.; Milentyeva, I.; Minina, V.; Kozlova, O.; Asyakina, L. Evaluation of the In Vivo Anti-Atherosclerotic Activity of Quercetin Isolated from the Hairy Roots of Hedysarum neglectum Ledeb. Life, 2023, 13(8), 1706. doi: 10.3390/life13081706
  348. Rapp, T.L.; DeForest, C.A. Tricolor visible wavelength-selective photodegradable hydrogel biomaterials. Nature Communications, 2023, 14, 5250. doi: 10.1038/s41467-023-40805-w
  349. Wu, R.; Prachyathipsakul, T.; Zhuang, J.; Liu, H.; Han, Y.; Liu, B.; Gong, S.; Qiu, J.; Wong, S.; Ribbe, A.; Medeiros, J.; Bhagabati, J.; Gao, J.; Wu, P.; Dutta, R.; Herrera, R.; Faraci, S.; Xiao, H.; Thayumanavan, S. Conferring liver selectivity to a thyromimetic using a novel nanoparticle increases therapeutic efficacy in a diet-induced obesity animal model. PNAS Nexus, 2023, 2(8), pgad252. doi: 10.1093/pnasnexus/pgad252
  350. Susnik, E.; Balog, S.; Taladriz-Blanco, P.; Petri-Fink, A.; Rothen-Rutishauser, B. The Functions of Cholera Toxin Subunit B as a Modulator of Silica Nanoparticle Endocytosis. Toxins, 2023, 15(8), 482. doi: 10.3390/toxins15080482
  351. Tsuchiya, M.; Tachibana, N.; Hamachi, I. Flow cytometric analysis of phosphatidylcholine metabolism using organelle-selective click labeling. STAR Protocols, 2023, 4(3), 102525. doi: 10.1016/j.xpro.2023.102525
  352. Matos, A.I.; Peres, C.; Carreira, B.; Moura, L.I.F.; Acúrcio, R.C.; Vogel, T.; Wegener, E.; Ribeiro, F.; Afonso, M.B.; Santos, F.M.F.; Martínez‐Barriocanal, Á.; Arango, D.; Viana, A.S.; Góis, P.M.P.; Silva, L.C.; Rodrigues, C.M.P.; Graca, L.; Jordan, R.; Satchi‐Fainaro, R.; Florindo, H.F. Polyoxazoline‐Based Nanovaccine Synergizes with Tumor‐Associated Macrophage Targeting and Anti‐PD‐1 Immunotherapy against Solid Tumors. Advanced Science, 2023, 10(25), 2300299. doi: 10.1002/advs.202300299
  353. Sindeeva, O.A.; Demina, P.A.; Kozyreva, Z.V.; Muslimov, A.R.; Gusliakova, O.I.; Laushkina, V.O.; Mordovina, E.A.; Tsyupka, D.; Epifanovskaya, O.S.; Sapach, A.Y..; Goryacheva, I.Y..; Sukhorukov, G.B. Labeling and Tracking of Individual Human Mesenchymal Stromal Cells Using Photoconvertible Fluorescent Microcapsules. International Journal of Molecular Sciences, 2023, 24(17), 13665. doi: 10.3390/ijms241713665
  354. Mariewskaya, K.A.; Gvozdev, D.A.; Chistov, A.A.; Straková, P.; Huvarová, I.; Svoboda, P.; Kotouček, J.; Ivanov, N.M.; Krasilnikov, M.S.; Zhitlov, M.Y.; Pak, A.M.; Mikhnovets, I.E.; Nikitin, T.D.; Korshun, V.A.; Alferova, V.A.; Mašek, J.; Růžek, D.; Eyer, L.; Ustinov, A.V. Membrane-Targeting Perylenylethynylphenols Inactivate Medically Important Coronaviruses via the Singlet Oxygen Photogeneration Mechanism. Molecules, 2023, 28(17), 6278. doi: 10.3390/molecules28176278
  355. Nakatsuji, M.; Sato, N.; Sakamoto, S.; Watanabe, K.; Teruuchi, Y.; Takeuchi, M.; Inui, T.; Ishihara, H. Non-electrostatic interactions associated with aggregate formation between polyallylamine and Escherichia coli. Scientific Reports, 2023, 13, 14793. doi: 10.1038/s41598-023-42120-2
  356. Latallo, M.J.; Wang, S.; Dong, D.; Nelson, B.; Livingston, N.M.; Wu, R.; Zhao, N.; Stasevich, T.J.; Bassik, M.C.; Sun, S.; Wu, B. Single-molecule imaging reveals distinct elongation and frameshifting dynamics between frames of expanded RNA repeats in C9ORF72-ALS/FTD. Nature Communications, 2023, 14, 5581. doi: 10.1038/s41467-023-41339-x
  357. Ramey-Ward, A.N.; Dong, Y.; Yang, J.; Ogasawara, H.; Bremer-Sai, E.C.; Brazhkina, O.; Franck, C.; Davis, M.; Salaita, K. Optomechanically Actuated Hydrogel Platform for Cell Stimulation with Spatial and Temporal Resolution. ACS Biomaterials Science & Engineering, 2023, 9(9), 5361-5375. doi: 10.1021/acsbiomaterials.3c00516
  358. Oerlemans, R.A.J.F.; Shao, J.; van Stevendaal, M.H.M.E.; Wu, H.; Patiño Padial, T.; Abdelmohsen, L.K.E.A.; van Hest, J.C.M. Biodegradable Grubbs-Loaded Artificial Organelles for Endosomal Ring-Closing Metathesis. Biomacromolecules, 2023, 24(9), 4148-4155. doi: 10.1021/acs.biomac.3c00487
  359. Meyer, S.; Blaas, I.; Bollineni, R.C.; Delic-Sarac, M.; Tran, T.T.; Knetter, C.; Dai, K.-Z.; Madssen, T.S.; Vaage, J.T.; Gustavsen, A.; Yang, W.; Nissen-Meyer, L.S.H.; Douvlataniotis, K.; Laos, M.; Nielsen, M.M.; Thiede, B.; Søraas, A.; Lund-Johansen, F.; Rustad, E.H.; Olweus, J. Prevalent and immunodominant CD8 T cell epitopes are conserved in SARS-CoV-2 variants. Cell Reports, 2023, 42(1), 111995. doi: 10.1016/j.celrep.2023.111995
  360. Tang, M.; Chen, B.; Xia, H.; Pan, M.; Zhao, R.; Zhou, J.; Yin, Q.; Wan, F.; Yan, Y.; Fu, C.; Zhong, L.; Zhang, Q.; Wang, Y. pH-gated nanoparticles selectively regulate lysosomal function of tumour-associated macrophages for cancer immunotherapy. Nature Communications, 2023, 14, 5888. doi: 10.1038/s41467-023-41592-0
  361. Prasanna, M.; Varela Calvino, R.; Lambert, A.; Arista Romero, M.; Pujals, S.; Trottein, F.; Camberlein, E.; Grandjean, C.; Csaba, N. Semisynthetic Pneumococcal Glycoconjugate Nanovaccine. Bioconjugate Chemistry, 2023, 34(9), 1563-1575. doi: 10.1021/acs.bioconjchem.3c00252
  362. Zhang, W.; Zhu, D.; Tong, Z.; Peng, B.; Cheng, X.; Esser, L.; Voelcker, N.H. Influence of Surface Ligand Density and Particle Size on the Penetration of the Blood–Brain Barrier by Porous Silicon Nanoparticles. Pharmaceutics, 2023, 15(9), 2271. doi: 10.3390/pharmaceutics15092271
  363. Feng, Y.; Cao, Y.; Qu, Z.; Janjua, T.I.; Popat, A. Virus-like Silica Nanoparticles Improve Permeability of Macromolecules across the Blood–Brain Barrier In Vitro. Pharmaceutics, 2023, 15(9), 2239. doi: 10.3390/pharmaceutics15092239
  364. Makeeva, A.; Muzaev, D.; Shubert, M.; Ianshina, T.; Sidorin, A.; Sambuk, E.; Rumyantsev, A.; Padkina, M. Alternative PCR-Based Approaches for Generation of Komagataella phaffii Strains. Microorganisms, 2023, 11(9), 2297. doi: 10.3390/microorganisms11092297
  365. Liu, J.X.; Haataja, M.P.; Košmrlj, A.; Datta, S.S.; Arnold, C.B.; Priestley, R.D. Liquid–liquid phase separation within fibrillar networks. Nature Communications, 2023, 14, 6085. doi: 10.1038/s41467-023-41528-8
  366. de Haas, R.J.; Ganar, K.A.; Deshpande, S.; de Vries, R. pH-Responsive Elastin-Like Polypeptide Designer Condensates. ACS Applied Materials & Interfaces, 2023, 15(38), 45336-45344. doi: 10.1021/acsami.3c11314
  367. Casella, B.M.; Farmer, J.P.; Nesheva, D.N.; Williams, H.E.L.; Charlton, S.J.; Holliday, N.D.; Laughton, C.A.; Mistry, S.N. Design, Synthesis, and Application of Fluorescent Ligands Targeting the Intracellular Allosteric Binding Site of the CXC Chemokine Receptor 2. Journal of Medicinal Chemistry, 2023, 66(18), 12911-12930. doi: 10.1021/acs.jmedchem.3c00849
  368. Frolov, A.V.; Akhmetova, L.A.; Vishnevskaya, M.S.; Kiriukhin, B.A.; Montreuil, O.; Lopes, F.; Tarasov, S.I. Amplicon metagenomics of dung beetles (Coleoptera , Scarabaeidae , Scarabaeinae) as a proxy for lemur ( Primates , Lemuroidea ) studies in Madagascar. ZooKeys, 2023, 1181, 29-39. doi: 10.3897/zookeys.1181.107496
  369. Ikonnikova, A.; Morozova, A.; Antonova, O.; Ochneva, A.; Fedoseeva, E.; Abramova, O.; Emelyanova, M.; Filippova, M.; Morozova, I.; Zorkina, Y.; Syunyakov, T.; Andryushchenko, A.; Andreuyk, D.; Kostyuk, G.; Gryadunov, D. Evaluation of the Polygenic Risk Score for Alzheimer’s Disease in Russian Patients with Dementia Using a Low-Density Hydrogel Oligonucleotide Microarray. International Journal of Molecular Sciences, 2023, 24(19), 14765. doi: 10.3390/ijms241914765
  370. Zharkov, T.D.; Mironova, E.M.; Markov, O.V.; Zhukov, S.A.; Khodyreva, S.N.; Kupryushkin, M.S. Fork- and Comb-like Lipophilic Structures: Different Chemical Approaches to the Synthesis of Oligonucleotides with Multiple Dodecyl Residues. International Journal of Molecular Sciences, 2023, 24(19), 14637. doi: 10.3390/ijms241914637
  371. Frolov, A.; Lobov, A.; Kabilov, M.; Zainullina, B.; Tupikin, A.; Shishkova, D.; Markova, V.; Sinitskaya, A.; Grigoriev, E.; Markova, Y.; Kutikhin, A. Multi-Omics Profiling of Human Endothelial Cells from the Coronary Artery and Internal Thoracic Artery Reveals Molecular but Not Functional Heterogeneity. International Journal of Molecular Sciences, 2023, 24(19), 15032. doi: 10.3390/ijms241915032
  372. Zahnreich, S.; El Guerzyfy, S.; Kaufmann, J.; Schmidberger, H. The cGAS/STING/IFN-1 Response in Squamous Head and Neck Cancer Cells after Genotoxic Challenges and Abrogation of the ATR-Chk1 and Fanconi Anemia Axis. International Journal of Molecular Sciences, 2023, 24(19), 14900. doi: 10.3390/ijms241914900
  373. Li, J.; Han, X.; Gao, S.; Yan, Y.; Li, X.; Wang, H. Tumor microenvironment-responsive DNA-based nanomedicine triggers innate sensing for enhanced immunotherapy. Journal of Nanobiotechnology, 2023, 21, 382. doi: 10.1186/s12951-023-02132-6
  374. Li, Y.; Ji, T.; Torre, M.; Shao, R.; Zheng, Y.; Wang, D.; Li, X.; Liu, A.; Zhang, W.; Deng, X.; Yan, R.; Kohane, D.S. Aromatized liposomes for sustained drug delivery. Nature Communications, 2023, 14, 6659. doi: 10.1038/s41467-023-41946-8
  375. Wang, K.; Zhang, X.; Ye, H.; Wang, X.; Fan, Z.; Lu, Q.; Li, S.; Zhao, J.; Zheng, S.; He, Z.; Ni, Q.; Chen, X.; Sun, J. Biomimetic nanovaccine-mediated multivalent IL-15 self-transpresentation (MIST) for potent and safe cancer immunotherapy. Nature Communications, 2023, 14, 6748. doi: 10.1038/s41467-023-42155-z
  376. El-Khoury, R.; Roman, M.; Assi, H.A.; Moye, A.L.; Bryan, T.M.; Damha, M.J. Telomeric i-motifs and C-strands inhibit parallel G-quadruplex extension by telomerase. Nucleic Acids Research, 2023, 51(19), 10395-10410. doi: 10.1093/nar/gkad764
  377. Sapozhnikova, Y.P.; Koroleva, A.G.; Yakhnenko, V.M.; Volkova, A.A.; Avezova, T.N.; Glyzina, O.Y..; Sakirko, M.V.; Tolstikova, L.I.; Sukhanova, L.V. Thermal Preconditioning Alters the Stability of Hump-Snout Whitefish (Coregonus fluviatilis) and Its Hybrid Form, Showing Potential for Aquaculture. Biology, 2023, 12(10), 1348. doi: 10.3390/biology12101348
  378. Psotta, C.; Nilsson, E.J.; Sjöberg, T.; Falk, M. Bacteria-Infected Artificial Urine Characterization Based on a Combined Approach Using an Electronic Tongue Complemented with 1 H-NMR and Flow Cytometry. Biosensors, 2023, 13(10), 916. doi: 10.3390/bios13100916
  379. Sinegubova, M.V.; Orlova, N.A.; Vorobiev, I.I. Promoter from Chinese hamster elongation factor-1a gene and Epstein-Barr virus terminal repeats concatemer fragment maintain stable high-level expression of recombinant proteins. PeerJ, 2023, 11, e16287. doi: 10.7717/peerj.16287
  380. Leccese, S.; Calcinoni, A.; Wilson, A.; Kirilovsky, D.; Carbonera, D.; Onfroy, T.; Jolivalt, C.; Mezzetti, A. Orange Carotenoid Protein in Mesoporous Silica: A New System towards the Development of Colorimetric and Fluorescent Sensors for pH and Temperature. Micromachines, 2023, 14(10), 1871. doi: 10.3390/mi14101871
  381. Gabashvili, A.N.; Chmelyuk, N.S.; Oda, V.V.; Leonova, M.K.; Sarkisova, V.A.; Lazareva, P.A.; Semkina, A.S.; Belyakov, N.A.; Nizamov, T.R.; Nikitin, P.I. Magnetic and Fluorescent Dual-Labeled Genetically Encoded Targeted Nanoparticles for Malignant Glioma Cell Tracking and Drug Delivery. Pharmaceutics, 2023, 15(10), 2422. doi: 10.3390/pharmaceutics15102422
  382. Wen, H.; Poutiainen, P.; Batnasan, E.; Latonen, L.; Lehto, V.-P.; Xu, W. Biomimetic Inorganic Nanovectors as Tumor-Targeting Theranostic Platform against Triple-Negative Breast Cancer. Pharmaceutics, 2023, 15(10), 2507. doi: 10.3390/pharmaceutics15102507
  383. Sridar, J.; Mafi, A.; Judge, R.A.; Xu, J.; Kong, K.A.; Wang, J.C.K.; Stoll, V.S.; Koukos, G.; Simon, R.J.; Eaton, D.; Bratkowski, M.; Hao, Q. Cryo-EM structure of human PAPP-A2 and mechanism of substrate recognition. Communications Chemistry, 2023, 6, 234. doi: 10.1038/s42004-023-01032-y
  384. McCarthy, K.P.; Go, D.B.; Senapati, S.; Chang, H.-C. An integrated ion-exchange membrane-based microfluidic device for irreversible dissociation and quantification of miRNA from ribonucleoproteins. Lab on a Chip, 2023, 23(2), 285-294. doi: 10.1039/d2lc00517d
  385. Białobrzewski, M.K.; Klepka, B.P.; Michaś, A.; Cieplak-Rotowska, M.K.; Staszałek, Z.; Niedźwiecka, A. Diversity of hydrodynamic radii of intrinsically disordered proteins. European Biophysics Journal, 2023, 52, 607-618. doi: 10.1007/s00249-023-01683-8
  386. Makri Pistikou, A.-M.; Cremers, G.A.O.; Nathalia, B.L.; Meuleman, T.J.; Bögels, B.W.A.; Eijkens, B.V.; de Dreu, A.; Bezembinder, M.T.H.; Stassen, O.M.J.A.; Bouten, C.C.V.; Merkx, M.; Jerala, R.; de Greef, T.F.A. Engineering a scalable and orthogonal platform for synthetic communication in mammalian cells. Nature Communications, 2023, 14, 7001. doi: 10.1038/s41467-023-42810-5
  387. Senavirathne, G.; London, J.; Gardner, A.; Fishel, R.; Yoder, K.E. DNA strand breaks and gaps target retroviral intasome binding and integration. Nature Communications, 2023, 14, 7072. doi: 10.1038/s41467-023-42641-4
  388. Sreekanth, K.V.; Perumal, J.; Dinish, U.S.; Prabhathan, P.; Liu, Y.; Singh, R.; Olivo, M.; Teng, J. Tunable Tamm plasmon cavity as a scalable biosensing platform for surface enhanced resonance Raman spectroscopy. Nature Communications, 2023, 14, 7085. doi: 10.1038/s41467-023-42854-7
  389. Williams, C.; Dong, K.C.; Arkinson, C.; Martin, A. Preparation of site-specifically fluorophore-labeled polyubiquitin chains for FRET studies of Cdc48 substrate processing. STAR protocols, 2023, 4(4), 102659. doi: 10.1016/j.xpro.2023.102659
  390. Li, G.; Lee, M.; Chang, T.-S.; Yu, J.; Li, H.; Duan, X.; Wu, X.; Jaiswal, S.; Feng, S.; Oldham, K.R.; Wang, T.D. Wide-field endoscope accessory for multiplexed fluorescence imaging. Scientific Reports, 2023, 13, 19527. doi: 10.1038/s41598-023-45955-x
  391. Bresinsky, M.; Shahraki, A.; Kolb, P.; Pockes, S.; Schihada, H. Development of Fluorescent AF64394 Analogues Enables Real-Time Binding Studies for the Orphan Class A GPCR GPR3. Journal of medicinal chemistry, 2023, 66(21), 15025-15041. doi: 10.1021/acs.jmedchem.3c01707
  392. Chung, K.; Booth, M.J. Sequence-independent, site-specific incorporation of chemical modifications to generate light-activated plasmids. Chemical Science, 2023, 14(44), 12693-12706. doi: 10.1039/d3sc02761a
  393. Mikhalchik, E.V.; Maltseva, L.N.; Firova, R.K.; Murina, M.A.; Gorudko, I.V.; Grigorieva, D.V.; Ivanov, V.A.; Obraztsova, E.A.; Klinov, D.V.; Shmeleva, E.V.; Gusev, S.A.; Panasenko, O.M.; Sokolov, A.V.; Gorbunov, N.P.; Filatova, L.Y.; Balabushevich, N.G. Incorporation of Pectin into Vaterite Microparticles Prevented Effects of Adsorbed Mucin on Neutrophil Activation. International Journal of Molecular Sciences, 2023, 24(21), 15927. doi: 10.3390/ijms242115927
  394. Fayzullina, D.; Yakushov, S.; Kantserova, K.; Belyaeva, E.; Aniskin, D.; Tsibulnikov, S.; Fayzullina, N.; Kalinin, S.; Romantsova, O.; Timashev, P.S.; Schroeder, B.A.; Ulasov, I.V. Carbonic Anhydrase Inhibitors Induce Ferroptosis through Inhibition of AKT/FTH1 Signaling in Ewing Sarcoma Tumor Cells. Cancers, 2023, 15(21), 5225. doi: 10.3390/cancers15215225
  395. Cossard, A.; Stam, K.; Smets, A.; Jossin, Y. MKL/SRF and Bcl6 mutual transcriptional repression safeguards the fate and positioning of neocortical progenitor cells mediated by RhoA. Science Advances, 2023, 9(46), eadd0676. doi: 10.1126/sciadv.add0676
  396. Cepeda Diaz, A.K.; Rudlaff, R.M.; Farringer, M.; Dvorin, J.D. Essential function of alveolin Pf IMC1g in the Plasmodium falciparum asexual blood stage. mBio, 2023, 14(5), e01507-23. doi: 10.1128/mbio.01507-23
  397. McGuire, K.; He, S.; Gracie, J.; Bryson, C.; Zheng, D.; Clark, A.W.; Koehnke, J.; France, D.J.; Nau, W.M.; Lee, T.-C.; Peveler, W.J. Supramolecular Click Chemistry for Surface Modification of Quantum Dots Mediated by Cucurbit[7]uril. ACS nano, 2023, 17(21), 21585-21594. doi: 10.1021/acsnano.3c06601
  398. Schmid, R.; Volcic, M.; Fischer, S.; Qu, Z.; Barth, H.; Popat, A.; Kirchhoff, F.; Lindén, M. Surface functionalization affects the retention and bio-distribution of orally administered mesoporous silica nanoparticles in a colitis mouse model. Scientific Reports, 2023, 13, 20175. doi: 10.1038/s41598-023-47445-6
  399. Kerr, M.D.; Johnson, W.T.; McBride, D.A.; Chumber, A.K.; Shah, N.J. Biodegradable scaffolds for enhancing vaccine delivery. Bioengineering & translational medicine, 2023, 8(6), e10591. doi: 10.1002/btm2.10591
  400. Pontes, A.P.; van der Wal, S.; Ranamalla, S.R.; Roelofs, K.; Tomuta, I.; Creemers, L.B.; Rip, J. Cell uptake and intracellular trafficking of bioreducible poly(amidoamine) nanoparticles for efficient mRNA translation in chondrocytes. Frontiers in Bioengineering and Biotechnology, 2023, 11, 1290871. doi: 10.3389/fbioe.2023.1290871
  401. Jarausch, B.; Markheiser, A.; Jarausch, W.; Biancu, S.; Kugler, S.; Runne, M.; Maixner, M. Risk Assessment for the Spread of Flavescence Dorée-Related Phytoplasmas from Alder to Grapevine by Alternative Insect Vectors in Germany. Microorganisms, 2023, 11(11), 2766. doi: 10.3390/microorganisms11112766
  402. Garanina, A.S.; Vishnevskiy, D.A.; Chernysheva, A.A.; Valikhov, M.P.; Malinovskaya, J.A.; Lazareva, P.A.; Semkina, A.S.; Abakumov, M.A.; Naumenko, V.A. Neutrophil as a Carrier for Cancer Nanotherapeutics: A Comparative Study of Liposome, PLGA, and Magnetic Nanoparticles Delivery to Tumors. Pharmaceuticals, 2023, 16(11), 1564. doi: 10.3390/ph16111564
  403. Shen, W.; You, T.; Xu, W.; Xie, Y.; Wang, Y.; Cui, M. Rapid and Widespread Distribution of Intranasal Small Extracellular Vesicles Derived from Mesenchymal Stem Cells throughout the Brain Potentially via the Perivascular Pathway. Pharmaceutics, 2023, 15(11), 2578. doi: 10.3390/pharmaceutics15112578
  404. Kang, J.‐Y.; Mun, D.; Chun, Y.; Park, D.‐S.; Kim, H.; Yun, N.; Joung, B. Engineered small extracellular vesicle‑mediated NOX4 siRNA delivery for targeted therapy of cardiac hypertrophy. Journal of Extracellular Vesicles, 2023, 12(10), 12371. doi: 10.1002/jev2.12371
  405. Sanghrajka, R.M.; Koche, R.; Medrano, H.; El Nagar, S.; Stephen, D.N.; Lao, Z.; Bayin, N.S.; Ge, K.; Joyner, A.L. KMT2D suppresses Sonic hedgehog-driven medulloblastoma progression and metastasis. iScience, 2023, 26(10), 107831. doi: 10.1016/j.isci.2023.107831
  406. Fornaguera, C.; Torres-Coll, A.; Olmo, L.; Garcia-Fernandez, C.; Guerra-Rebollo, M.; Borrós, S. Engineering oncogene-targeted anisamide-functionalized pBAE nanoparticles as efficient lung cancer antisense therapies. Rsc Advances, 2023, 13(43), 29986-30001. doi: 10.1039/d3ra05830a
  407. Thomas, B.J.; Guldenpfennig, C.; Guan, Y.; Winkler, C.; Beecher, M.; Beedy, M.; Berendzen, A.F.; Ma, L.; Daniels, M.A.; Burke, D.H.; Porciani, D. Targeting lung cancer with clinically relevant EGFR mutations using anti-EGFR RNA aptamer. Molecular Therapy. Nucleic Acids, 2023, 34, 102046. doi: 10.1016/j.omtn.2023.102046
  408. Paiola, M.; McGuire, C.C.; Lopez Ruiz, V.; De Jesús Andino, F.; Robert, J. Larval T Cells Are Functionally Distinct from Adult T Cells in Xenopus laevis. ImmunoHorizons, 2023, 7(10), 696-707. doi: 10.4049/immunohorizons.2300081
  409. Molina, M.; Way, L.E.; Ren, Z.; Liao, Q.; Guerra, B.; Shields, B.; Wang, X.; Kim, H.J. A framework to validate fluorescently labeled DNA-binding proteins for single-molecule experiments. Cell reports methods, 2023, 3(10), 100614. doi: 10.1016/j.crmeth.2023.100614
  410. Dietz, L.; Oberländer, J.; Mateos‐Maroto, A.; Schunke, J.; Fichter, M.; Krämer‐Albers, E.‐M.; Landfester, K.; Mailänder, V. Uptake of extracellular vesicles into immune cells is enhanced by the protein corona. Journal of Extracellular Vesicles, 2023, 12(12), e12399. doi: 10.1002/jev2.12399
  411. Wiest, M.J.; Baert, L.; Gu, C.; Gayler, K.M.; Ham, H.; Gorvel, L.; Keddis, M.T.; Griffing, L.W.; Joo, H.M.; Gorvel, J.-P.; Billadeau, D.D.; Kane, R.R.; Oh, S.K. Endosomal trafficking inhibitor EGA can control TLR7-mediated IFNα expression by human plasmacytoid dendritic cells. Frontiers in Immunology, 2023, 14, 1202197. doi: 10.3389/fimmu.2023.1202197
  412. Zhong, Y.; Maruf, A.; Qu, K.; Milewska, M.; Wandzik, I.; Mou, N.; Cao, Y.; Wu, W. Nanogels with covalently bound and releasable trehalose for autophagy stimulation in atherosclerosis. Journal of Nanobiotechnology, 2023, 21, 472. doi: 10.1186/s12951-023-02248-9
  413. Sotnikov, D.V.; Byzova, N.A.; Zherdev, A.V.; Dzantiev, B.B. Ability of Antibodies Immobilized on Gold Nanoparticles to Bind Small Antigen Fluorescein. International Journal of Molecular Sciences, 2023, 24(23), 16967. doi: 10.3390/ijms242316967
  414. Gunitseva, N.; Evteeva, M.; Korzhenkov, A.; Patrushev, M. A New RNA-Dependent Cas12g Nuclease. International Journal of Molecular Sciences, 2023, 24(23), 17105. doi: 10.3390/ijms242317105
  415. Goryunova, S.; Sivolapova, A.; Polivanova, O.; Sotnikova, E.; Meleshin, A.; Gaitova, N.; Egorova, A.; Semenov, A.; Gins, E.; Koroleva, A.; Moskalev, E.; Oves, E.; Kazakov, O.; Troitsky, A.; Goryunov, D. Comparative Study of Plastomes in Solanum tuberosum with Different Cytoplasm Types. Plants, 2023, 12(23), 3995. doi: 10.3390/plants12233995
  416. Yoo, W.; Song, Y.W.; Kim, J.; Ahn, J.; Kim, J.; Shin, Y.; Ryu, J.-K.; Kim, K.K. Molecular basis for SOX2-dependent regulation of super-enhancer activity. Nucleic Acids Research, 2023, 51(22), 11999-12019. doi: 10.1093/nar/gkad908
  417. Zhang, S.; Cheng, Y.; Gao, Y.; Zou, Y.; Xiao, W.; Li, T.; Li, M.; Yu, B.; Dong, J. Fluorescence quenching-based immunological probe for ticagrelor monitoring. Frontiers in Bioengineering and Biotechnology, 2023, 11, 1295406. doi: 10.3389/fbioe.2023.1295406
  418. Frolov, A.V.; Vishnevskaya, M.S.; Akhmetova, L.A. Diet shift in giant Madagascan dung beetle Helictopleurus giganteus (Coleoptera: Scarabaeidae: Scarabaeinae) studied by amplicon metagenomics. Proceedings of the Zoological Institute RAS, 2023, 327(4), 719-723. doi: 10.31610/trudyzin/2023.327.4.719
  419. Marina, V.I.; Bidzhieva, M.; Tereshchenkov, A.G.; Orekhov, D.; Sagitova, V.E.; Sumbatyan, N.V.; Tashlitsky, V.N.; Ferberg, A.S.; Maviza, T.P.; Kasatsky, P.; Tolicheva, O.; Paleskava, A.; Polshakov, V.I.; Osterman, I.A.; Dontsova, O.A.; Konevega, A.L.; Sergiev, P.V. An easy tool to monitor the elemental steps of in vitro translation via gel electrophoresis of fluorescently labeled small peptides. RNA, 2023, 30(3), 298-307. doi: 10.1261/rna.079766.123
  420. Tuzikov, A.; Shilova, N.; Ovchinnikova, T.; Nokel, A.; Patova, O.; Knirel, Y.; Chernova, T.; Gorshkova, T.; Bovin, N. Labeling of Polysaccharides with Biotin and Fluorescent Dyes. Polysaccharides, 2023, 5(1), 1-15. doi: 10.3390/polysaccharides5010001
  421. Li, Z.; Kovshova, T.; Malinovskaya, J.; Valikhov, M.; Melnikov, P.; Osipova, N.; Maksimenko, O.; Dhakal, N.; Chernysheva, A.; Chekhonin, V.; Gelperina, S.; Wacker, M.G. Modeling the Drug delivery Lifecycle of PLG Nanoparticles Using Intravital Microscopy. Small, 2023, 2306726. doi: 10.1002/smll.202306726
  422. Jiang, Y.; Xu, Y.; Zhu, C.; Xu, G.; Xu, L.; Rao, Z.; Zhou, L.; Jiang, P.; Malik, S.; Fang, J.; Lin, H.; Zhang, M. STAT3 palmitoylation initiates a positive feedback loop that promotes the malignancy of hepatocellular carcinoma cells in mice. Science signaling, 2023, 16(814). doi: 10.1126/scisignal.add2282
  423. Leung, W.; Baxley, R.M.; Traband, E.; Chang, Y.-C.; Rogers, C.B.; Wang, L.; Durrett, W.; Bromley, K.S.; Fiedorowicz, L.; Thakar, T.; Tella, A.; Sobeck, A.; Hendrickson, E.A.; Moldovan, G.-L.; Shima, N.; Bielinsky, A.-K. FANCD2-dependent mitotic DNA synthesis relies on PCNA K164 ubiquitination. Cell reports, 2023, 42(12), 113523. doi: 10.1016/j.celrep.2023.113523
  424. Nandana, V.; Rathnayaka-Mudiyanselage, I.W.; Muthunayake, N.S.; Hatami, A.; Mousseau, C.B.; Ortiz-Rodríguez, L.A.; Vaishnav, J.; Collins, M.; Gega, A.; Mallikaarachchi, K.S.; Yassine, H.; Ghosh, A.; Biteen, J.S.; Zhu, Y.; Champion, M.M.; Childers, W.S.; Schrader, J.M. The BR-body proteome contains a complex network of protein-protein and protein-RNA interactions. Cell reports, 2023, 42(10), 113229. doi: 10.1016/j.celrep.2023.113229
  425. Schissel, C.K.; Farquhar, C.E.; Loas, A.; Malmberg, A.B.; Pentelute, B.L. In-Cell Penetration Selection–Mass Spectrometry Produces Noncanonical Peptides for Antisense Delivery. ACS chemical biology, 2023, 18(3), 615-628. doi: 10.1021/acschembio.2c00920
  426. Hebels, E.R.; Dietl, S.; Timmers, M.; Hak, J.; van den Dikkenberg, A.; Rijcken, C.J.F.; Hennink, W.E.; Liskamp, R.M.J.; Vermonden, T. Versatile Click Linker Enabling Native Peptide Release from Nanocarriers upon Redox Trigger. Bioconjugate chemistry, 2023, 34(12), 2375-2386. doi: 10.1021/acs.bioconjchem.3c00484
  427. Gafarova, E.; Kuracji, D.; Sogomonyan, K.; Gorokhov, I.; Polev, D.; Zubova, E.; Golikova, E.; Granovitch, A.; Maltseva, A. Gut Bacteriomes and Ecological Niche Divergence: An Example of Two Cryptic Gastropod Species. Biology, 2023, 12(12), 1521. doi: 10.3390/biology12121521
  428. Kirikovich, S.S.; Levites, E.V.; Proskurina, A.S.; Ritter, G.S.; Peltek, S.E.; Vasilieva, A.R.; Ruzanova, V.S.; Dolgova, E.V.; Oshihmina, S.G.; Sysoev, A.V.; Koleno, D.I.; Danilenko, E.D.; Taranov, O.S.; Ostanin, A.A.; Chernykh, E.R.; Kolchanov, N.A.; Bogachev, S.S. The Molecular Aspects of Functional Activity of Macrophage-Activating Factor GcMAF. International Journal of Molecular Sciences, 2023, 24(24), 17396. doi: 10.3390/ijms242417396
  429. Potapenko, E.Y..; Kashko, N.D.; Knorre, D.A. Spontaneous Mutations in Saccharomyces cerevisiae mtDNA Increase Cell-to-Cell Variation in mtDNA Amount. International Journal of Molecular Sciences, 2023, 24(24), 17413. doi: 10.3390/ijms242417413
  430. Silchenko, A.S.; Kalinovsky, A.I.; Avilov, S.A.; Popov, R.S.; Chingizova, E.A.; Menchinskaya, E.S.; Zelepuga, E.A.; Panina, E.G.; Stepanov, V.G.; Kalinin, V.I.; Dmitrenok, P.S. Sulfated Triterpene Glycosides from the Far Eastern Sea Cucumber Cucumaria djakonovi : Djakonoviosides C 1 , D 1 , E 1 , and F 1 ; Cytotoxicity against Human Breast Cancer Cell Lines; Quantitative Structure–Activity Relationships. Marine Drugs, 2023, 21(12), 602. doi: 10.3390/md21120602
  431. Bauer, I.; Ilina, E.; Zharkov, T.; Grigorieva, E.; Chinak, O.; Kupryushkin, M.; Golyshev, V.; Mitin, D.; Chubarov, A.; Khodyreva, S.; Dmitrienko, E. Self-Penetrating Oligonucleotide Derivatives: Features of Self-Assembly and Interactions with Serum and Intracellular Proteins. Pharmaceutics, 2023, 15(12), 2779. doi: 10.3390/pharmaceutics15122779
  432. Khramtsov, Y.V.; Ulasov, A.V.; Slastnikova, T.A.; Rosenkranz, A.A.; Lupanova, T.N.; Georgiev, G.P.; Sobolev, A.S. Modular Nanotransporters Delivering Biologically Active Molecules to the Surface of Mitochondria. Pharmaceutics, 2023, 15(12), 2687. doi: 10.3390/pharmaceutics15122687
  433. Olea, A.R.; Jurado, A.; Slor, G.; Tevet, S.; Pujals, S.; De La Rosa, V.R.; Hoogenboom, R.; Amir, R.J.; Albertazzi, L. Reaching the Tumor: Mobility of Polymeric Micelles Inside an In Vitro Tumor-on-a-Chip Model with Dual ECM. ACS Applied Materials & Interfaces, 2023, 15(51), 59134-59144. doi: 10.1021/acsami.3c12798
  434. Kulkarni, A.; Jozefiaková, J.; Bhide, K.; Mochnaćová, E.; Bhide, M. Differential transcriptome response of blood brain barrier spheroids to neuroinvasive Neisseria and Borrelia. Frontiers in Cellular and Infection Microbiology, 2023, 13, 1326578. doi: 10.3389/fcimb.2023.1326578
  435. Truong, N.; Cottingham, A.L.; Dharmaraj, S.; Shaw, J.R.; Lasola, J.J.M.; Goodis, C.C.; Fletcher, S.; Pearson, R.M. Multimodal nanoparticle‐containing modified suberoylanilide hydroxamic acid polymer conjugates to mitigate immune dysfunction in severe inflammation. Bioengineering & Translational Medicine, 2023, 9(1), e10611. doi: 10.1002/btm2.10611
  436. Ko, Y.H.; Nguyen, H.H.T.; Branstetter, C.R.; Park, S.; Lee, J.-K.; Yang, J.; Jung, J.P.; Kim, M. Single-Component Hydrophilic Terpolymer Thin Film Systems for Imparting Surface Chemical Versatility on Various Substrates. Polymers, 2023, 16(1), 44. doi: 10.3390/polym16010044
  437. Shramova, E.I.; Frolova, A.Y..; Filimonova, V.P.; Deyev, S.M.; Proshkina, G.M. System for Self-excited Targeted Photodynamic Therapy Based on the Multimodal Protein DARP-NanoLuc-SOPP3. Acta Naturae, 2023, 15(4), 100-110. doi: 10.32607/actanaturae.27331
  438. Khramtsov, Y.V.; Ulasov, A.V.; Lupanova, T.N.; Slastnikova, T.A.; Rosenkranz, A.A.; Bunin, E.S.; Georgiev, G.P.; Sobolev, A.S. Intracellular Degradation of SARS-CoV-2 N-Protein Caused by Modular Nanotransporters Containing Anti-N-Protein Monobody and a Sequence That Recruits the Keap1 E3 Ligase. Pharmaceutics, 2023, 16(1), 4. doi: 10.3390/pharmaceutics16010004
  439. Drekolia, M.-K.; Karantanou, C.; Wittig, I.; Li, Y.; Fuhrmann, D.C.; Brüne, B.; Katsouda, A.; Hu, J.; Papapetropoulos, A.; Bibli, S.-I. Loss of cardiac mitochondrial complex I persulfidation impairs NAD + homeostasis in aging. Redox Biology, 2023, 69, 103014. doi: 10.1016/j.redox.2023.103014
  440. Loo, S.; Kam, A.; Dutta, B.; Zhang, X.; Feng, N.; Sze, S.K.; Liu, C.-F.; Wang, X.; Tam, J.P. Broad-spectrum ginsentides are principal bioactives in unraveling the cure-all effects of ginseng. Acta Pharmaceutica Sinica B, 2023, 14(2), 653-666. doi: 10.1016/j.apsb.2023.10.022
  441. Zou, Y.; Sabljić, I.; Horbach, N.; Dauphinee, A.N.; Åsman, A.; Sancho Temino, L.; Minina, E.A.; Drag, M.; Stael, S.; Poreba, M.; Ståhlberg, J.; Bozhkov, P.V. Thermoprotection by a cell membrane–localized metacaspase in a green alga. The Plant Cell, 2023, 36(3), 665-687. doi: 10.1093/plcell/koad289
  442. Kasza, K.; Elsherbeny, A.; Moloney, C.; Hardie, K.R.; Cámara, M.; Alexander, C.; Gurnani, P. Hybrid Poly( β ‐amino ester) Triblock Copolymers Utilizing a RAFT Polymerization Grafting‐From Methodology. Macromolecular Chemistry and Physics, 2023, 224(24), 2300262. doi: 10.1002/macp.202300262
  443. Sueldo, D.J.; Godson, A.; Kaschani, F.; Krahn, D.; Kessenbrock, T.; Buscaill, P.; Schofield, C.J.; Kaiser, M.; van der Hoorn, R.A.L. Activity‐based proteomics uncovers suppressed hydrolases and a neo ‐functionalised antibacterial enzyme at the plant–pathogen interface. The New Phytologist, 2023, 241(1), 394-408. doi: 10.1111/nph.18857
  444. Damasco, J.A.; Yu, G.; Kumar, A.; Perez, J.; Lirag, R.C.M.; Whitley, E.M.; Lin, S.-H.; Melancon, M.P. Alendronate Conjugate for Targeted Delivery to Bone-Forming Prostate Cancer. Talanta, 2023, 256, 124308. doi: 10.1016/j.talanta.2023.124308
  445. Lamson, N. G.; Pickering, A. J.; Wyckoff, J.; Ganesh, P.; Calle, E. A.; Straehla, J. P.; Hammond, P. T. Trafficking through the Blood–Brain Barrier Is Directed by Core and Outer Surface Components of Layer-by-Layer Nanoparticles. Bioengineering & Translational Medicine, 2023, e10636. doi: 10.1002/btm2.10636
  446. Rodgers, M.L.; O’Brien, B.; Woodson, S.A. Small RNAs and Hfq capture unfolded RNA target sites during transcription. Molecular Cell, 2023, 83(9), 1489-1501.e5. doi: 10.1016/j.molcel.2023.04.003
  447. Aung, A.; Cui, A.; Maiorino, L.; Amini, A.P.; Gregory, J.R.; Bukenya, M.; Zhang, Y.; Lee, H.; Cottrell, C.A.; Morgan, D.M.; Silva, M.; Suh, H.; Kirkpatrick, J.D.; Amlashi, P.; Remba, T.; Froehle, L.M.; Xiao, S.; Abraham, W.; Adams, J.; Love, J.C.; Huyett, P.; Kwon, D.S.; Hacohen, N.; Schief, W.R.; Bhatia, S.N.; Irvine, D.J. Low protease activity in B cell follicles promotes retention of intact antigens after immunization. Science, 2023, 379(6630), eabn8934. doi: 10.1126/science.abn8934
  448. Gonzales, G.; Hoque, J.; Gilpin, A.; Maity, B.; Zauscher, S.; Varghese, S. Branched poly‐ l ‐lysine for cartilage penetrating carriers. Bioengineering & Translational Medicine, 2023, 9(3), e10612. doi: 10.1002/btm2.10612
  449. Hast, K.; Stone, M.R.L.; Jia, Z.; Baci, M.; Aggarwal, T.; Izgu, E.C. Bioorthogonal Functionalization of Material Surfaces with Bioactive Molecules. ACS Applied Materials & Interfaces, 2023, 15(4), 4996-5009. doi: 10.1021/acsami.2c20942
  450. Yao, P.; Liu, R.; Broggini, T.; Thunemann, M.; Kleinfeld, D. Construction and Use of an Adaptive Optics Two-Photon Microscope with Direct Wavefront Sensing. Nat Protoc, 2023, 18(12), 3732–3766. doi: 10.1038/s41596-023-00893-w

2022

  1. Jalloh, S.; Olejnik, J.; Berrigan, J.; Nisa, A.; Suder, E. L.; Akiyama, H.; Lei, M.; Ramaswamy, S.; Tyagi, S.; Bushkin, Y.; Mühlberger, E.; Gummuluru, S. CD169-Mediated Restrictive SARS-CoV-2 Infection of Macrophages Induces pro-Inflammatory Responses. PLOS Pathogens, 2022, 18(10), e1010479. doi: 10.1371/journal.ppat.1010479
  2. Rumyantsev, A.; Sidorin, A.; Volkov, A.; Al Shanaa, O.; Sambuk, E.; Padkina, M. Transcriptome Analysis Unveils the Effects of Proline on Gene Expression in the Yeast Komagataella phaffii. Microorganisms, 2022, 10(1), 67. doi: 10.3390/microorganisms10010067
  3. Wilson, A.D.; Richards, M.A.; Curtis, M.K.; Gunadasa-Rohling, M.; Monterisi, S.; Loonat, A.A.; Miller, J.J.; Ball, V.; Lewis, A.; Tyler, D.J.; Moshnikova, A.; Andreev, O.A.; Reshetnyak, Y.K.; Carr, C.; Swietach, P. Acidic environments trigger intracellular H + -sensing FAK proteins to re-balance sarcolemmal acid–base transporters and auto-regulate cardiomyocyte pH. Cardiovascular Research, 2022, 118(14), 2946-2959. doi: 10.1093/cvr/cvab364
  4. Arora, A.; Goering, R.; Velez, P.T.; Taliaferro, J.M. Visualization and quantification of subcellular RNA localization using single molecule RNA fluorescence in situ hybridization. Post-Transcriptional Gene Regulation. Methods in molecular biology, 2022, 2404, 247-266. doi: 10.1007/978-1-0716-1851-6_13
  5. Moody, C.T.; Brown, A.E.; Massaro, N.P.; Patel, A.S.; Agarwalla, P.A.; Simpson, A.M.; Brown, A.C.; Zheng, H.; Pierce, J.G.; Brudno, Y. Restoring Carboxylates on Highly Modified Alginates Improves Gelation, Tissue Retention and Systemic Capture. Acta Biomaterialia, 2022, 138, 208-217. doi: 10.1016/j.actbio.2021.10.046
  6. Boffoli, D.; Bellato, F.; Avancini, G.; Gurnani, P.; Yilmaz, G.; Romero, M.; Robertson, S.; Moret, F.; Sandrelli, F.; Caliceti, P.; Salmaso, S.; Cámara, M.; Mantovani, G.; Mastrotto, F. Tobramycin-Loaded Complexes to Prevent and Disrupt Pseudomonas Aeruginosa Biofilms. Drug Deliv. and Transl. Res., 2022, 12(8), 1788–1810. doi: 10.1007/s13346-021-01085-3
  7. Kuiper, E. F. E.; Gallardo, P.; Bergsma, T.; Mari, M.; Kolbe Musskopf, M.; Kuipers, J.; Giepmans, B. N. G.; Steen, A.; Kampinga, H. H.; Veenhoff, L. M.; Bergink, S. The Chaperone DNAJB6 Surveils FG-Nucleoporins and Is Required for Interphase Nuclear Pore Complex Biogenesis. Nat Cell Biol, 2022, 24(11), 1584–1594. doi: 10.1038/s41556-022-01010-x
  8. Melnikov, N. P.; Bolshakov, F. V.; Frolova, V. S.; Skorentseva, K. V.; Ereskovsky, A. V.; Saidova, A. A.; Lavrov, A. I. Tissue Homeostasis in Sponges: Quantitative Analysis of Cell Proliferation and Apoptosis. Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, 2022, 338(6), 360–381. doi: 10.1002/jez.b.23138
  9. Maltsev, D. I.; Mellanson, K. A.; Belousov, V. V.; Enikolopov, G. N.; Podgorny, O. V. The Bioavailability Time of Commonly Used Thymidine Analogues after Intraperitoneal Delivery in Mice: Labeling Kinetics in Vivo and Clearance from Blood Serum. Histochem Cell Biol, 2022, 157(2), 239–250. doi: 10.1007/s00418-021-02048-y
  10. Yan, Y.; Zhou, L.; Sun, Z.; Song, D.; Cheng, Y. Targeted and Intracellular Delivery of Protein Therapeutics by a Boronated Polymer for the Treatment of Bone Tumors. Bioactive Materials, 2022, 7, 333–340. doi: 10.1016/j.bioactmat.2021.05.041
  11. Emelyanova, M.; Pokataev, I.; Shashkov, I.; Kopantseva, E.; Lyadov, V.; Heydarov, R.; Mikhailovich, V. TYMS 3′-UTR Polymorphism: A Novel Association with FOLFIRINOX-Induced Neurotoxicity in Pancreatic Cancer Patients. Pharmaceutics, 2022, 14(1), 77. doi: 10.3390/pharmaceutics14010077
  12. Fischer, N. G.; Kobe, A. C.; Dai, J.; He, J.; Wang, H.; Pizarek, J. A.; De Jong, D. A.; Ye, Z.; Huang, S.; Aparicio, C. Tapping Basement Membrane Motifs: Oral Junctional Epithelium for Surface-Mediated Soft Tissue Attachment to Prevent Failure of Percutaneous Devices. Acta Biomaterialia, 2022, 141, 70–88. doi: 10.1016/j.actbio.2021.12.030
  13. Santos-Coquillat, A.; González, M. I.; Clemente-Moragón, A.; González-Arjona, M.; Albaladejo-García, V.; Peinado, H.; Muñoz, J.; Ximénez Embún, P.; Ibañez, B.; Oliver, E.; Desco, M.; Salinas, B. Goat Milk Exosomes As Natural Nanoparticles for Detecting Inflammatory Processes By Optical Imaging. Small, 2022, 18(6), 2105421. doi: 10.1002/smll.202105421
  14. Zuo, Z.; He, L.; Duan, X.; Peng, Z.; Han, J. Glycyrrhizic Acid Exhibits Strong Anticancer Activity in Colorectal Cancer Cells via SIRT3 Inhibition. Bioengineered, 2022, 13(2), 2720–2731. doi: 10.1080/21655979.2021.2001925
  15. Lee, J. H.; Song, J.; Kim, I. G.; You, G.; Kim, H.; Ahn, J.-H.; Mok, H. Exosome-Mediated Delivery of Transforming Growth Factor-β Receptor 1 Kinase Inhibitors and Toll-like Receptor 7/8 Agonists for Combination Therapy of Tumors. Acta Biomaterialia, 2022, 141, 354–363. doi: 10.1016/j.actbio.2022.01.005
  16. White, M. J.; Raczy, M. M.; Budina, E.; Yuba, E.; Solanki, A.; Shim, H.-N.; Zhang, Z. J.; Gray, L. T.; Cao, S.; Alpar, A. T.; Hubbell, J. A. Engineered Collagen-Targeting Therapeutics Reverse Lung and Kidney Fibrosis in Mice. bioRxiv, 2022, preprint. doi: 10.1101/2022.01.04.474747
  17. Alshanski, I.; Shitrit, A.; Sukhran, Y.; Unverzagt, C.; Hurevich, M.; Yitzchaik, S. Effect of Interfacial Properties on Impedimetric Biosensing of the Sialylation Process with a Biantennary N-Glycan-Based Monolayer. Langmuir, 2022, 38(2), 849–855. doi: 10.1021/acs.langmuir.1c02995
  18. Selnihhin, D.; Mortensen, K. I.; Larsen, J. B.; Simonsen, J. B.; Pedersen, F. S. DNA Origami Calibrators for Counting Fluorophores on Single Particles by Flow Cytometry. Small Methods, 2022, 6(3), 2101364. doi: 10.1002/smtd.202101364
  19. Yan, Y.; Chen, B.; Yin, Q.; Wang, Z.; Yang, Y.; Wan, F.; Wang, Y.; Tang, M.; Xia, H.; Chen, M.; Liu, J.; Wang, S.; Zhang, Q.; Wang, Y. Dissecting Extracellular and Intracellular Distribution of Nanoparticles and Their Contribution to Therapeutic Response by Monochromatic Ratiometric Imaging. Nat Commun, 2022, 13(1), 2004. doi: 10.1038/s41467-022-29679-6
  20. Elangovan, A.; Suresh, D.; Tarim, A. O.; Upendran, A.; Kannan, R. Controlled Assembly of Gold and Albumin Nanoparticles to Form Hybrid Multimeric Nanomaterials. Polymers for Advanced Technologies, 2022, 33(2), 566–575. doi: 10.1002/pat.5538
  21. Kesarwani, V.; Walker, J. A.; Henderson, E. C.; Huynh, G.; McLiesh, H.; Graham, M.; Wieringa, M.; Banaszak Holl, M. M.; Garnier, G.; Corrie, S. R. Column Agglutination Assay Using Polystyrene Microbeads for Rapid Detection of Antibodies against SARS-CoV-2. ACS Appl. Mater. Interfaces, 2022, 14(2), 2501–2509. doi: 10.1021/acsami.1c17859
  22. Arranz-Gibert, P.; Vanderschuren, K.; Haimovich, A.; Halder, A.; Gupta, K.; Rinehart, J.; Isaacs, F. J. Chemoselective Restoration of Para-Azido-Phenylalanine at Multiple Sites in Proteins. Cell Chemical Biology, 2022, 29(6), 1046-1052.e4. doi: 10.1016/j.chembiol.2021.12.002
  23. Ksenofontov, A. A.; Bocharov, P. S.; Ksenofontova, K. V.; Antina, E. V. Water-Soluble BODIPY-Based Fluorescent Probe for BSA and HSA Detection. Journal of Molecular Liquids, 2022, 345, 117031. doi: 10.1016/j.molliq.2021.117031
  24. Tähtinen, V.; Gulumkar, V.; Maity, S. K.; Yliperttula, A.-M.; Siekkinen, S.; Laine, T.; Lisitsyna, E.; Haapalehto, I.; Viitala, T.; Vuorimaa-Laukkanen, E.; Yliperttula, M.; Virta, P. Assembly of Bleomycin Saccharide-Decorated Spherical Nucleic Acids. Bioconjugate Chem., 2022, 33(1), 206–218. doi: 10.1021/acs.bioconjchem.1c00539
  25. Wei, W.; Zhang, D.; Wang, C.; Zhang, Y.; An, S.; Chen, Y.; Huang, G.; Liu, J. Annotating CD38 Expression in Multiple Myeloma with [18F]F–Nb1053. Mol. Pharmaceutics, 2022, 19(10), 3502–3510. doi: 10.1021/acs.molpharmaceut.1c00733
  26. Kafle, C. M.; Anderson, A. Y.; Prakash, A.; Swedik, S.; Bridge, E. An Adenovirus Early Region 4 Deletion Mutant Induces G2/M Arrest via ATM Activation and Reduces Expression of the Mitotic Marker Phosphorylated (Ser10) Histone 3. Virology, 2022, 565, 1–12. doi: 10.1016/j.virol.2021.09.006
  27. Mohammad-Beigi, H.; Zanganeh, M.; Scavenius, C.; Eskandari, H.; Farzadfard, A.; Shojaosadati, S. A.; Enghild, J. J.; Otzen, D. E.; Buell, A. K.; Sutherland, D. S. A Protein Corona Modulates Interactions of α-Synuclein with Nanoparticles and Alters the Rates of the Microscopic Steps of Amyloid Formation. ACS Nano, 2022, 16(1), 1102–1118. doi: 10.1021/acsnano.1c08825
  28. Schotman, M. J. G.; Fransen, P.-P.; Song, J.; W. Dankers, P. Y. Tuning the Affinity of Amphiphilic Guest Molecules in a Supramolecular Polymer Transient Network. RSC Advances, 2022, 12(22), 14052–14060. doi: 10.1039/D2RA00346E
  29. Reyes, A. F.; Goldusky, J.; Bhimalli, P.; Marzo, A. L.; Schneider, J. R. Tracking Fluorescently Labeled IL-15 and Anti-PD-1 in the Tumor Microenvironment and Draining Lymph Nodes. Journal of Immunological Methods, 2022, 505, 113253. doi: 10.1016/j.jim.2022.113253.
  30. Krausova, K.; Charousova, M.; Kratochvil, Z.; Takacsova, P.; Tesarova, B.; Sivak, L.; Peskova, M. K.; Sukupova, M.; Zivotska, H.; Makovicky, P.; Yamashita, I.; Okamoto, N.; Hynek, D.; Haddad, Y.; Pekarik, V.; Rex, S.; Heger, Z. Toward Understanding the Kinetics of Disassembly of Ferritins of Varying Origin and Subunit Composition. Applied Materials Today, 2022, 28, 101535. doi: 10.1016/j.apmt.2022.101535
  31. Liu, X.; Ren, X.; Zhou, L.; Liu, K.; Deng, L.; Qing, Q.; Li, J.; Zhi, F.; Li, M. Tollip Orchestrates Macrophage Polarization to Alleviate Intestinal Mucosal Inflammation. Journal of Crohn’s and Colitis, 2022, 16(7), 1151–1167. doi: 10.1093/ecco-jcc/jjac019
  32. Kim, Y. M.; Lee, K.; Lee, Y.; Yang, K.; Choe, D.; Roh, Y. H. Thermoresponsive Semi-Interpenetrating Gelatin-Alginate Networks for Encapsulation and Controlled Release of Scent Molecules. International Journal of Biological Macromolecules, 2022, 208, 1096–1105. doi: 10.1016/j.ijbiomac.2022.03.185
  33. Kalinovsky, D. V.; Kibardin, A. V.; Kholodenko, I. V.; Svirshchevskaya, E. V.; Doronin, I. I.; Konovalova, M. V.; Grechikhina, M. V.; Rozov, F. N.; Larin, S. S.; Deyev, S. M.; Kholodenko, R. V. Therapeutic Efficacy of Antibody-Drug Conjugates Targeting GD2-Positive Tumors. J Immunother Cancer, 2022, 10(5), e004646. doi: 10.1136/jitc-2022-004646
  34. Sposito, B.; Mambu, J.; Gwilt, K. B.; Spinelli, L.; Andreeva, N.; Galland, F.; Naquet, P.; Mitsialis, V.; Thiagarajah, J. R.; Snapper, S. B.; Broggi, A.; Zanoni, I. Type III Interferons Induce Pyroptosis in Gut Epithelial Cells and Delay Tissue Restitution upon Acute Intestinal Injury. bioRxiv, 2022, preprint. doi: 10.1101/2022.03.04.482997
  35. Cierzniak, A.; Kaliszewski, K.; Małodobra-Mazur, M. The Preliminary Evaluation of Epigenetic Modifications Regulating the Expression of IL10 in Insulin-Resistant Adipocytes. Genes, 2022, 13(2), 294. doi: 10.3390/genes13020294
  36. Han, G.; Kim, H.; Kim, D. E.; Ahn, Y.; Kim, J.; Jang, Y. J.; Kim, K.; Yang, Y.; Kim, S. H. The Potential of Bovine Colostrum-Derived Exosomes to Repair Aged and Damaged Skin Cells. Pharmaceutics, 2022, 14(2), 307. doi: 10.3390/pharmaceutics14020307
  37. Zhang, W.; Zhang, S.; Chen, C.; Liu, N.; Yang, D.; Wang, P.; Ren, F. The Internalization Mechanisms and Trafficking of the Pea Albumin in Caco-2 Cells. International Journal of Biological Macromolecules, 2022, 217, 111–119. doi: 10.1016/j.ijbiomac.2022.06.149
  38. Ikonnikova, A.; Rodina, T.; Dmitriev, A.; Melnikov, E.; Kazakov, R.; Nasedkina, T. The Influence of the CES1 Genotype on the Pharmacokinetics of Enalapril in Patients with Arterial Hypertension. Journal of Personalized Medicine, 2022, 12(4), 580. doi: 10.3390/jpm12040580
  39. Mishyn, V.; Hugo, A.; Rodrigues, T.; Aspermair, P.; Happy, H.; Marques, L.; Hurot, C.; Othmen, R.; Bouchiat, V.; Boukherroub, R.; Knoll, W.; Szunerits, S. The Holy Grail of Pyrene-Based Surface Ligands on the Sensitivity of Graphene-Based Field Effect Transistors. Sens. Diagn., 2022, 1(2), 235–244.. doi: 10.1039/D1SD00036E
  40. Borkosky, S. S.; Fassolari, M.; Campos-León, K.; Rossi, A. H.; Salgueiro, M.; Pascuale, C.; Martínez, R. P.; Gaston, K.; Gay, G. de P. The Guardian of the Genome Meets a Viral Master Gene Regulator at a Biomolecular Condensate. bioRxiv, 2022, preprint. doi: 10.1101/2022.02.09.479752
  41. Gaglia, G.; Kabraji, S.; Rammos, D.; Dai, Y.; Verma, A.; Wang, S.; Mills, C.; Chung, M.; Bergholz, J.; Coy, S.; Lin, J.-R.; Jeselsohn, R.; Metzger, O.; Winer, E.; Dillon, D.; Zhao, J.; Sorger, P.; Santagata, S. Temporal and Spatial Topography of Cell Proliferation in Cancer. Nature Cell Biology, 2022, 24, 316–326. doi: 10.1038/s41556-022-00860-9
  42. Petit, P.-F.; Bombart, R.; Desimpel, P.-H.; Naulaerts, S.; Thouvenel, L.; Collet, J.-F.; Van Den Eynde, B. J.; Zhu, J. T Cell–Mediated Targeted Delivery of Anti–PD-L1 Nanobody Overcomes Poor Antibody Penetration and Improves PD-L1 Blocking at the Tumor Site. Cancer Immunology Research, 2022, 10(5), 713–727. doi: 10.1158/2326-6066.CIR-21-0801
  43. Zhdanov, G. A.; Gribanyov, D. A.; Gambaryan, A. S.; Kukushkin, V. I.; Zavyalova, E. G. Using a Biosensor Based on Surface-Enhanced Raman Scattering to Identify Influenza Viruses in Biological Fluids. Bull. Russ. Acad. Sci. Phys., 2022, 86(4), 434–437. doi: 10.3103/S1062873822040293
  44. Ma, X.; Bai, Y.; Liu, K.; Han, Y.; Zhang, J.; Liu, Y.; Hou, X.; Hao, E.; Hou, Y.; Bai, G. Ursolic Acid Inhibits the Cholesterol Biosynthesis and Alleviates High Fat Diet-Induced Hypercholesterolemia via Irreversible Inhibition of HMGCS1 in Vivo. Phytomedicine, 2022, 103, 154233. doi: 10.1016/j.phymed.2022.154233
  45. Sokolova, V.; Ebel, J.-F.; Kollenda, S.; Klein, K.; Kruse, B.; Veltkamp, C.; Lange, C. M.; Westendorf, A. M.; Epple, M. Uptake of Functional Ultrasmall Gold Nanoparticles in 3D Gut Cell Models. Small, 2022, 18(31), 2201167. doi: 10.1002/smll.202201167
  46. Schmitz, V.; Ochoa, M. T.; Teles, R. M. B.; Jo, E.-K. Editorial: Strategies Played by Immune Cells and Mycobacteria in the Battle between Antimicrobial Activity and Bacterial Survival. Front. Immunol., 2022, 13. doi: 10.3389/fimmu.2022.869692
  47. Chumakov, D.; Kichkailo, A.; Zamay, G.; Burov, A.; Khlebtsov, N. Synthesis and Characteristics of Fluorescent Red-Emitting DNA-Templated Silver Nanoclusters Based on Aptamer Selected to Lung Cancer. Computational Biophysics and Nanobiophotonics: SPIE, 2022, 12194, 245–250. doi: 10.1117/12.2626120
  48. Latorre, R.; Ramírez-Garcia, P. D.; Hegron, A.; Grace, J. L.; Retamal, J. S.; Shenoy, P.; Tran, M.; Aurelio, L.; Flynn, B.; Poole, D. P.; Klein-Cloud, R.; Jensen, D. D.; Davis, T. P.; Schmidt, B. L.; Quinn, J. F.; Whittaker, M. R.; Veldhuis, N. A.; Bunnett, N. W. Sustained Endosomal Release of a Neurokinin-1 Receptor Antagonist from Nanostars Provides Long-Lasting Relief of Chronic Pain. Biomaterials, 2022, 285, 121536. doi: 10.1016/j.biomaterials.2022.121536
  49. Tang, W.; Panja, S.; Jogdeo, C. M.; Tang, S.; Yu, A.; Oupický, D. Study of Renal Accumulation of Targeted Polycations in Acute Kidney Injury. Biomacromolecules, 2022, 23(5), 2064–2074. doi: 10.1021/acs.biomac.2c00079
  50. Müller, C.; Gleixner, J.; Tahk, M.-J.; Kopanchuk, S.; Laasfeld, T.; Weinhart, M.; Schollmeyer, D.; Betschart, M. U.; Lüdeke, S.; Koch, P.; Rinken, A.; Keller, M. Structure-Based Design of High-Affinity Fluorescent Probes for the Neuropeptide Y Y1 Receptor. J. Med. Chem., 2022, 65(6), 4832–4853. doi: 10.1021/acs.jmedchem.1c02033
  51. Alakesh, A.; Jothiprakasam, T.; Raghavan, J. V.; Jhunjhunwala, S. Sterile Inflammation Alters Neutrophil Kinetics in Mice. Journal of Leukocyte Biology, 2022, 112(3), 395–409. doi: 10.1002/JLB.1A0321-132RR
  52. Li, W.; Hadjigol, S.; Mazo, A. R.; Holden, J.; Lenzo, J.; Shirbin, S. J.; Barlow, A.; Shabani, S.; Huang, T.; Reynolds, E. C.; Qiao, G. G.; O’Brien-Simpson, N. M. Star-Peptide Polymers Are Multi-Drug-Resistant Gram-Positive Bacteria Killers. ACS Appl. Mater. Interfaces, 2022, 14(22), 25025–25041. doi: 10.1021/acsami.1c23734
  53. Drexel, M.; Rahimi, S.; Sperk, G. Silencing of Hippocampal Somatostatin Interneurons Induces Recurrent Spontaneous Limbic Seizures in Mice. Neuroscience, 2022, 487, 155–165. doi: 10.1016/j.neuroscience.2022.02.007
  54. Liu, H.; Hu, Z.; Chen, H.; Yan, Y.; Le, Z.; Wei, C.; Cao, W.; Chen, T.; Chen, Y.; Liu, L. Self-Degradable Poly(β-Amino Ester)s Promote Endosomal Escape of Antigen and Agonist. Journal of Controlled Release, 2022, 345, 91–100. doi: 10.1016/j.jconrel.2022.03.006
  55. Li, M.; Huang, J.; Ma, M.; Shi, X.; Li, L. Selective Enrichment of Sialylglycopeptides Enabled by Click Chemistry and Dynamic Covalent Exchange. Anal. Chem., 2022, 94(18), 6681–6688.. doi: 10.1021/acs.analchem.1c05158
  56. Nonaka, S.; Kadowaki, T.; Nakanishi, H. Secreted Gingipains from Porphyromonas Gingivalis Increase Permeability in Human Cerebral Microvascular Endothelial Cells through Intracellular Degradation of Tight Junction Proteins. Neurochemistry International, 2022, 154, 105282. doi: 10.1016/j.neuint.2022.105282
  57. Pletnev, P. I.; Shulenina, O.; Evfratov, S.; Treshin, V.; Subach, M. F.; Serebryakova, M. V.; Osterman, I. A.; Paleskava, A.; Bogdanov, A. A.; Dontsova, O. A.; Konevega, A. L.; Sergiev, P. V. Ribosomal Protein S18 Acetyltransferase RimI Is Responsible for the Acetylation of Elongation Factor Tu. Journal of Biological Chemistry, 2022, 298(5), 101914. doi: 10.1016/j.jbc.2022.101914
  58. Kuwabara, J. T.; Hara, A.; Heckl, J. R.; Peña, B.; Bhutada, S.; DeMaris, R.; Ivey, M. J.; DeAngelo, L. P.; Liu, X.; Park, J.; Jahansooz, J. R.; Mestroni, L.; McKinsey, T. A.; Apte, S. S.; Tallquist, M. D. Regulation of Extracellular Matrix Composition by Fibroblasts during Perinatal Cardiac Maturation. Journal of Molecular and Cellular Cardiology, 2022, 169, 84–95. doi: 10.1016/j.yjmcc.2022.05.003
  59. Ji, F.; Wang, S.; Shao, S.; Sarkar, P.; Xue, M. Real-Time Analysis of AKT Signaling Activities at Single-Cell Resolution Using Cyclic Peptide-Based Probes. Biomedical Engineering Technologies: Methods in Molecular Biology, 2022, 2394, 65–80. doi: 10.1007/978-1-0716-1811-0_5
  60. Monakhova, M. V.; Kubareva, E. A.; Kolesnikov, K. K.; Anashkin, V. A.; Kosaretskiy, E. M.; Zvereva, M. I.; Romanova, E. A.; Friedhoff, P.; Oretskaya, T. S.; Zatsepin, T. S. Reactive Acrylamide-Modified DNA Traps for Accurate Cross-Linking with Cysteine Residues in DNA–Protein Complexes Using Mismatch Repair Protein MutS as a Model. Molecules, 2022, 27(8), 2438. doi: 10.3390/molecules27082438
  61. Michielsen, C. M. S.; van Aalen, E. A.; Merkx, M. Ratiometric Bioluminescent Zinc Sensor Proteins to Quantify Serum and Intracellular Free Zn2+. ACS Chem. Biol., 2022, 17(6), 1567–1576. doi: 10.1021/acschembio.2c00227
  62. Fu, H.-J.; Su, R.; Luo, L.; Chen, Z.-J.; Sørensen, T. J.; Hildebrandt, N.; Xu, Z.-L. Rapid and Wash-Free Time-Gated FRET Histamine Assays Using Antibodies and Aptamers. ACS Sens., 2022, 7(4), 1113–1121. doi: 10.1021/acssensors.2c00085
  63. Son, T.; Cho, Y.-J.;Lee, H.; Cho, M.Y.; Goh, B.; Kim, H.M.; Phan, H.Th.N.; Cho, S.-H.; Park, Y.-J.; Park, H.S. Quantitative Assessment of the Size-dependent Whole-body to Cellular Biodistribution of Fine Particulate Matters Following Inhalation by Fluorescence Imaging. Research Square, 2022, preprint. doi: 10.21203/rs.3.rs-1230726/v1
  64. Alì, A.; Leibowitz, D.; Bhatt, N.; Doubrovin, M.; Bates-Pappas, G. E.; Taub, R. N.; McKiernan, J. M.; Mintz, A.; Molotkov, A. Preliminary Efficacy of [90Y] DOTA-Biotin-Avidin Radiotherapy against Non-Muscle Invasive Bladder Cancer. Research Square, 2022, preprint. doi: 10.21203/rs.3.rs-1559077/v1
  65. Najer, A.; Blight, J.; Ducker, C. B.; Gasbarri, M.; Brown, J. C.; Che, J.; Høgset, H.; Saunders, C.; Ojansivu, M.; Lu, Z.; Lin, Y.; Yeow, J.; Rifaie-Graham, O.; Potter, M.; Tonkin, R.; Penders, J.; Doutch, J. J.; Georgiadou, A.; Barriga, H. M. G.; Holme, M. N.; Cunnington, A. J.; Bugeon, L.; Dallman, M. J.; Barclay, W. S.; Stellacci, F.; Baum, J.; Stevens, M. M. Potent Virustatic Polymer–Lipid Nanomimics Block Viral Entry and Inhibit Malaria Parasites In Vivo. ACS Cent. Sci., 2022, 8(9), 1238–1257. doi: 10.1021/acscentsci.1c01368
  66. Liu, H.; Wu, S.; Lee, H.; Baudo, G.; Massaro, M.; Zhang, A.; Hamilton, D. J.; Blanco, E. Polymer-Functionalized Mitochondrial Transplantation to Plaque Macrophages as a Therapeutic Strategy Targeting Atherosclerosis. Advanced Therapeutics, 2022, 5(5), 2100232. doi: 10.1002/adtp.202100232
  67. Yang, Y.; Kozlovskaya, V.; Zhang, Z.; Xing, C.; Zaharias, S.; Dolmat, M.; Qian, S.; Zhang, J.; Warram, J. M.; Yang, E. S.; Kharlampieva, E. Poly(N-Vinylpyrrolidone)-Block-Poly(Dimethylsiloxane)-Block-Poly(N-Vinylpyrrolidone) Triblock Copolymer Polymersomes for Delivery of PARP1 SiRNA to Breast Cancers. ACS Appl. Bio Mater., 2022, 5(4), 1670–1682. doi: 10.1021/acsabm.2c00063
  68. Hernández-Coronado, M.; Dias Araujo, P. C.; Ip, P.-L.; Nunes, C. O.; Rahni, R.; Wudick, M. M.; Lizzio, M. A.; Feijó, J. A.; Birnbaum, K. D. Plant Glutamate Receptors Mediate a Bet-Hedging Strategy between Regeneration and Defense. Developmental Cell, 2022, 57(4), 451-465.e6. doi: 10.1016/j.devcel.2022.01.013
  69. Maingret, V.; Chartier, C.; Six, J.-L.; Schmitt, V.; Héroguez, V. Pickering Emulsions Stabilized by Biodegradable Dextran-Based Nanoparticles Featuring Enzyme Responsiveness and Co-Encapsulation of Actives. Carbohydrate Polymers, 2022, 284, 119146. doi: 10.1016/j.carbpol.2022.119146
  70. Chetverikov, P. E.; Rector, B. G.; Tonkel, K.; Dimitri, L.; Cheglakov, D. S.; Romanovich, A. E.; Amrine, J. Phylogenetic Position of a New Trisetacus Mite Species (Nalepellidae) Destroying Seeds of North American Junipers and New Hypotheses on Basal Divergence of Eriophyoidea. Insects, 2022, 13(2), 201. doi: 10.3390/insects13020201
  71. Klöcker, N.; Weissenboeck, F. P.; van Dülmen, M.; Špaček, P.; Hüwel, S.; Rentmeister, A. Photocaged 5′ Cap Analogues for Optical Control of MRNA Translation in Cells. Nat. Chem., 2022, 14(8), 905–913. doi: 10.1038/s41557-022-00972-7
  72. Khadria, A.; Paavola, C. D.; Maslov, K.; Valenzuela, F. A.; Sperry, A. E.; Cox, A. L.; Cao, R.; Shi, J.; Brown-Augsburger, P. L.; Lozano, E.; Blankenship, R. L.; Majumdar, R.; Bradley, S. A.; Beals, J. M.; Oladipupo, S. S.; Wang, L. V. Photoacoustic Imaging Reveals Mechanisms of Rapid-Acting Insulin Formulations Dynamics at the Injection Site. Molecular Metabolism, 2022, 62, 101522. doi: 10.1016/j.molmet.2022.101522
  73. Vellecco, V.; Panza, E.; Bibli, S.-I.; Casillo, G. M.; Raucci, F.; Manzo, O. L.; Smimmo, M.; Villani, R.; Cavezza, M. R.; Fleming, I.; d’Emmanuele di Villa Bianca, R.; Maione, F.; Cirino, G.; Bucci, M. Phosphodiesterases S-Sulfhydration Contributes to Human Skeletal Muscle Function. Pharmacological Research, 2022, 177, 106108. doi: 10.1016/j.phrs.2022.106108
  74. Utterström, J.; Barriga, H. M. G.; Holme, M. N.; Selegård, R.; Stevens, M. M.; Aili, D. Peptide-Folding Triggered Phase Separation and Lipid Membrane Destabilization in Cholesterol-Rich Lipid Vesicles. Bioconjugate Chem., 2022, 33(4), 736–746. doi: 10.1021/acs.bioconjchem.2c00115
  75. He, Y.; Hong, C.; Fletcher, S. J.; Berger, A. G.; Sun, X.; Yang, M.; Huang, S.; Belcher, A. M.; Irvine, D. J.; Li, J.; Hammond, P. T. Peptide-Based Cancer Vaccine Delivery via the STINGΔTM-CGAMP Complex. Advanced Healthcare Materials, 2022, 11(15), 2200905. doi: 10.1002/adhm.202200905
  76. Li, Y.; Lofchy, L.; Wang, G.; Gaikwad, H.; Fujita, M.; Simberg, D. PEGylated Liposomes Accumulate in the Areas Relevant to Skin Toxicities via Passive Extravasation across “Leaky” Endothelium. ACS Nano, 2022, 16(4), 6349–6358. doi: 10.1021/acsnano.2c00423
  77. Kim, S.; Heo, R.; Song, S. H.; Song, K.-H.; Shin, J. M.; Oh, S. J.; Lee, H.-J.; Chung, J. E.; Park, J. H.; Kim, T. W. PD-L1 SiRNA–Hyaluronic Acid Conjugate for Dual-Targeted Cancer Immunotherapy. Journal of Controlled Release, 2022, 346, 226–239. doi: 10.1016/j.jconrel.2022.04.023
  78. Travanut, A.; F. Monteiro, P.; Smith, S.; M. Howdle, S.; M. Grabowska, A.; Kellam, B.; R. Meier, M. A.; Alexander, C. Passerini Chemistries for Synthesis of Polymer Pro-Drug and Polymersome Drug Delivery Nanoparticles. Journal of Materials Chemistry B, 2022, 10(20), 3895–3905. doi: 10.1039/D2TB00045H
  79. Zhao, P.; Liu, S.; Koriath, A. T.; Gao, X. Partial Magneto-Endosomalysis for Cytosolic Delivery of Antibodies. Bioconjugate Chem., 2022, 33(2), 363–368. doi: 10.1021/acs.bioconjchem.1c00598
  80. Conod, A.; Silvano, M.; Ruiz i Altaba, A. On the Origin of Metastases: Induction of pro-Metastatic States after Impending Cell Death via ER Stress, Reprogramming, and a Cytokine Storm. Cell Reports, 2022, 38(10), 110490. doi: 10.1016/j.celrep.2022.110490
  81. Park, J. S.; Lim, Y. G.; Park, K. Novel Bidentate β-Glutamic Acid-Based Bone-Targeting Agents for in Vivo Bone Imaging. Journal of Industrial and Engineering Chemistry, 2022, 110, 471–478. doi: 10.1016/j.jiec.2022.03.021
  82. Li, C.; Yang, Q.; Chen, Z.; Qiu, Y.; Du, Y.; Wang, R.; He, Q.; Yang, J.; Zhen, H.; Kang, L. Noninvasive Evaluation of Multidrug Resistance via Imaging of ABCG2/BCRP Multidrug Transporter in Lung Cancer Xenograft Models. Mol. Pharmaceutics, 2022, 19(10), 3521–3529. doi: 10.1021/acs.molpharmaceut.1c00939
  83. Budke, B.; Zhong, A.; Sullivan, K.; Park, C.; Gittin, D. I.; Kountz, T. S.; Connell, P. P. Noncanonical NF-ΚB Factor P100/P52 Regulates Homologous Recombination and Modulates Sensitivity to DNA-Damaging Therapy. Nucleic Acids Research, 2022, 50(11), 6251–6263. doi: 10.1093/nar/gkac491
  84. Massó-Vallés, D.; Beaulieu, M.-E.; Jauset, T.; Giuntini, F.; Zacarías-Fluck, M. F.; Foradada, L.; Martínez-Martín, S.; Serrano, E.; Martín-Fernández, G.; Casacuberta-Serra, S.; Castillo Cano, V.; Kaur, J.; López-Estévez, S.; Morcillo, M. Á.; Alzrigat, M.; Mahmoud, L.; Luque-García, A.; Escorihuela, M.; Guzman, M.; Arribas, J.; Serra, V.; Larsson, L.-G.; Whitfield, J. R.; Soucek, L. MYC Inhibition Halts Metastatic Breast Cancer Progression by Blocking Growth, Invasion, and Seeding. Cancer Research Communications, 2022, 2(2), 110–130. doi: 10.1158/2767-9764.CRC-21-0103
  85. Hagemans, I. M.; Wierstra, P. J.; Steuten, K.; Molkenboer-Kuenen, J. D. M.; van Dalen, D.; ter Beest, M.; van der Schoot, J. M. S.; Ilina, O.; Gotthardt, M.; Figdor, C. G.; Scheeren, F. A.; Heskamp, S.; Verdoes, M. Multiscale Imaging of Therapeutic Anti-PD-L1 Antibody Localization Using Molecularly Defined Imaging Agents. Journal of Nanobiotechnology, 2022, 20(1), 64. doi: 10.1186/s12951-022-01272-5
  86. Santiana, J.J. ; Sawant, S.S.; Gomez, N.; Rouge, J. L. Multi-Layered Stimuli Responsive DNA Micelles for the Stepwise Controlled Release of Small Molecules. Journal of Materials Chemistry B, 2022, 10(37), 7518–7526. doi: 10.1039/D1TB02722K
  87. Son, T.; Cho, Y.-J.; Lee, H.; Cho, M. Y.; Goh, B.; Kim, H. M.; Hoa, P. T. N.; Cho, S.-H.; Park, Y.-J.; Park, H. S.; Hong, K. S. Monitoring in Vivo Behavior of Size-Dependent Fluorescent Particles as a Model Fine Dust. Journal of Nanobiotechnology, 2022, 20(1), 227. doi: 10.1186/s12951-022-01419-4
  88. Wu, F.; Gardinier, T. C.; Turker, M. Z.; Chen, F.; Chen, P.-M.; Venkatesan, A. M.; Patel, V.; Adams, G. P.; Bradbury, M. S.; Wiesner, U. B.; Germano, G.; Ma, K. Molecular Engineering of Surface Functional Groups Enabling Clinical Translation of Nanoparticle–Drug Conjugates. Chem. Mater., 2022, 34(12), 5344–5355. doi: 10.1021/acs.chemmater.1c04447
  89. Hong, C.; Alser, O.; Gebran, A.; He, Y.; Joo, W.; Kokoroskos, N.; Velmahos, G.; Olsen, B. D.; Hammond, P. T. Modulating Nanoparticle Size to Understand Factors Affecting Hemostatic Efficacy and Maximize Survival in a Lethal Inferior Vena Cava Injury Model. ACS Nano, 2022, 16(2), 2494–2510. doi: 10.1021/acsnano.1c09108
  90. Tang, W.; Panja, S.; Jogdeo, C. M.; Tang, S.; Ding, L.; Yu, A.; Foster, K. W.; Dsouza, D. L.; Chhonker, Y. S.; Jensen-Smith, H.; Jang, H.-S.; Boesen, E. I.; Murry, D. J.; Padanilam, B.; Oupický, D. Modified Chitosan for Effective Renal Delivery of SiRNA to Treat Acute Kidney Injury. Biomaterials, 2022, 285, 121562. doi: 10.1016/j.biomaterials.2022.121562
  91. Mousa, A. H.; Bliman, D.; Hiram Betancourt, L.; Hellman, K.; Ekström, P.; Savvakis, M.; Strakosas, X.; Marko-Varga, G.; Berggren, M.; Hjort, M.; Ek, F.; Olsson, R. Method Matters: Exploring Alkoxysulfonate-Functionalized Poly(3,4-Ethylenedioxythiophene) and Its Unintentional Self-Aggregating Copolymer toward Injectable Bioelectronics. Chem. Mater., 2022, 34(6), 2752–2763. doi: 10.1021/acs.chemmater.1c04342
  92. Aupič, J.; Lapenta, F.; Strmšek, Ž.; Merljak, E.; Plaper, T.; Jerala, R. Metal Ion–Regulated Assembly of Designed Modular Protein Cages. Science Advances, 2022, 8(24), eabm8243. doi: 10.1126/sciadv.abm8243
  93. Zheng, T.; Zhang, Q.; Peng, Z.; Li, D.; Wu, X.; Liu, Y.; Li, P.; Zhang, J.; Du, G. Metabolite-Based Cell Sorting Workflow for Identifying Microbes Producing Carbonyls in Tobacco Leaves. Appl Microbiol Biotechnol, 2022, 106(11), 4199–4209. doi: 10.1007/s00253-022-11982-3
  94. Hu, L.; Wang, J.; Lin, D.; Shen, Y.; Huang, H.; Cao, Y.; Li, Y.; Li, K.; Yu, Y.; Yu, Y.; Chu, C.; Qin, L.; Wang, X.; Zhang, H.; Fulton, D.; Chen, F. Mesenchymal Stem Cell–Derived Nanovesicles as a Credible Agent for Therapy of Pulmonary Hypertension. Am J Respir Cell Mol Biol, 2022, 67(1), 61–75. doi: 10.1165/rcmb.2021-0415OC
  95. Casey, L. M.; Hughes, K. R.; Saunders, M. N.; Miller, S. D.; Pearson, R. M.; Shea, L. D. Mechanistic Contributions of Kupffer Cells and Liver Sinusoidal Endothelial Cells in Nanoparticle-Induced Antigen-Specific Immune Tolerance. Biomaterials, 2022, 283, 121457. doi: 10.1016/j.biomaterials.2022.121457
  96. Backes, I. M.; Byrd, B. K.; Slein, M. D.; Patel, C. D.; Taylor, S. A.; Garland, C. R.; MacDonald, S. W.; Balazs, A. B.; Davis, S. C.; Ackerman, M. E.; Leib, D. A. Maternally Transferred MAbs Protect Neonatal Mice from HSV-Induced Mortality and Morbidity. Journal of Experimental Medicine, 2022, 219(12), e20220110. doi: 10.1084/jem.20220110
  97. Wang, Z.; Chen, D.; Guan, D.; Liang, X.; Xue, J.; Zhao, H.; Song, G.; Lou, J.; He, Y.; Zhang, H. Material Properties of Phase-Separated TFEB Condensates Regulate the Autophagy-Lysosome Pathway. Journal of Cell Biology, 2022, 221(5), e202112024. doi: 10.1083/jcb.202112024
  98. Caronna, F.; Glimpel, N.; Paar, G.-P.; Gries, T.; Blaeser, A.; Do, K.; B. Dolan, E.; Ronan, W. Manufacturing, Characterization, and Degradation of a Poly(Lactic Acid) Warp-Knitted Spacer Fabric Scaffold as a Candidate for Tissue Engineering Applications. Biomaterials Science, 2022, 10(14), 3793–3807. doi: 10.1039/D1BM02027G
  99. Grzelak, J.; Gázquez, J.; Grayston, A.; Teles, M.; Herranz, F.; Roher, N.; Rosell, A.; Roig, A.; Gich, M. Magnetic Mesoporous Silica Nanorods Loaded with Ceria and Functionalized with Fluorophores for Multimodal Imaging. ACS Appl. Nano Mater., 2022, 5(2), 2113–2125. doi: 10.1021/acsanm.1c03837
  100. Wang, Y.; Zhang, Y.; Guan, Y.; Zhang, Y. Magnetic Field-Assisted Fast Assembly of Microgel Colloidal Crystals. Langmuir, 2022, 38(19), 6057–6065. doi: 10.1021/acs.langmuir.2c00297
  101. Bose, M.; Lampe, M.; Mahamid, J.; Ephrussi, A. Liquid-to-Solid Phase Transition of Oskar Ribonucleoprotein Granules Is Essential for Their Function in Drosophila Embryonic Development. Cell, 2022, 185(8), 1308-1324.e23. doi: 10.1016/j.cell.2022.02.022
  102. Zhao, Y.; Liu, T.; Ardana, A.; Fletcher, N. L.; Houston, Z. H.; Blakey, I.; Thurecht, K. J. Investigation of a Dual SiRNA/Chemotherapy Delivery System for Breast Cancer Therapy. ACS Omega, 2022, 7(20), 17119–17127. doi: 10.1021/acsomega.2c00620
  103. Warmt, C.; Yaslanmaz, C.; Henkel, J. Investigation and Validation of Labelling Loop Mediated Isothermal Amplification (LAMP) Products with Different Nucleotide Modifications for Various Downstream Analysis. Sci Rep, 2022, 12(1), 7137. doi: 10.1038/s41598-022-11320-7
  104. Macdougall, L. J.; Hoffman, T. E.; Kirkpatrick, B. E.; Fairbanks, B. D.; Bowman, C. N.; Spencer, S. L.; Anseth, K. S. Intracellular Crowding by Bio-Orthogonal Hydrogel Formation Induces Reversible Molecular Stasis. Advanced Materials, 2022, 34(31), 2202882. doi: 10.1002/adma.202202882
  105. Liu, J.; Lu, F.; Chen, Y.; Plow, E.; Qin, J. Integrin Mediates Cell Entry of the SARS-CoV-2 Virus Independent of Cellular Receptor ACE2. Journal of Biological Chemistry, 2022, 298(3), 101710. doi: 10.1016/j.jbc.2022.101710
  106. Nkanga, C. I.; Ortega-Rivera, O. A.; Shin, M. D.; Moreno-Gonzalez, M. A.; Steinmetz, N. F. Injectable Slow-Release Hydrogel Formulation of a Plant Virus-Based COVID-19 Vaccine Candidate. Biomacromolecules, 2022, 23(4), 1812–1825. doi: 10.1021/acs.biomac.2c00112
  107. Grodetskaya, T. A.; Evlakov, P. M.; Fedorova, O. A.; Mikhin, V. I.; Zakharova, O. V.; Kolesnikov, E. A.; Evtushenko, N. A.; Gusev, A. A. Influence of Copper Oxide Nanoparticles on Gene Expression of Birch Clones In Vitro under Stress Caused by Phytopathogens. Nanomaterials, 2022, 12(5), 864. doi: 10.3390/nano12050864
  108. Radler, P.; Baranova, N.; Caldas, P.; Sommer, C.; López-Pelegrín, M.; Michalik, D.; Loose, M. In Vitro Reconstitution of Escherichia Coli Divisome Activation. Nat Commun, 2022, 13(1), 2635. doi: 10.1038/s41467-022-30301-y
  109. Kikuma, T.; Ibuki, H.; Nakamoto, M.; Seko, A.; Ito, Y.; Takeda, Y. In Vitro Mannosidase Activity of EDEM3 against Asparagine-Linked Oligomannose-Type Glycans. Biochemical and Biophysical Research Communications, 2022, 612, 44–49. doi: 10.1016/j.bbrc.2022.04.094
  110. Fujii, S.; Takano, S.; Nakazawa, K.; Sakurai, K. Impact of Zwitterionic Polymers on the Tumor Permeability of Molecular Bottlebrush-Based Nanoparticles. Biomacromolecules, 2022, 23(7), 2846–2855. doi: 10.1021/acs.biomac.2c00216
  111. Barmin, R. A.; Rudakovskaya, P. G.; Chernyshev, V. S.; Guslyakova, O. I.; Sindeeva, O. A.; Prikhozhdenko, E. S.; Bratashov, D. N.; Abdurashitov, A. S.; Maksimova, E. A.; Demina, P. A.; Khaydukov, E. V.; Gayer, A. V.; Shirshin, E. A.; Solovev, A. A.; Mei, Y.; Gorin, D. A. Impact of Fluorescent Dyes on the Physicochemical Parameters of Microbubbles Stabilized by Albumin-Dye Complex. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2022, 647, 129095. doi: 10.1016/j.colsurfa.2022.129095
  112. Chen, S.; Li, W.; Zheng, X.; Yu, P.; Wang, P.; Sun, Z.; Xu, Y.; Jiao, D.; Ye, X.; Cai, M.; Shen, M.; Wang, M.; Zhang, Q.; Kong, F.; Wang, Y.; He, J.; Wei, H.; Shi, F.; Du, J. Immunomagnetic Microscopy of Tumor Tissues Using Quantum Sensors in Diamond. Proc. Natl. Acad. Sci. U.S.A., 2022, 119(5), e2118876119. doi: 10.1073/pnas.2118876119
  113. Tian, T.; Liang, R.; Erel-Akbaba, G.; Saad, L.; Obeid, P. J.; Gao, J.; Chiocca, E. A.; Weissleder, R.; Tannous, B. A. Immune Checkpoint Inhibition in GBM Primed with Radiation by Engineered Extracellular Vesicles. ACS Nano, 2022, 16(2), 1940–1953. doi: 10.1021/acsnano.1c05505
  114. Lu, M.; Huang, X.; Cai, X.; Sun, J.; Liu, X.; Weng, L.; Zhu, L.; Luo, Q.; Chen, Z. Hypoxia-Responsive Stereocomplex Polymeric Micelles with Improved Drug Loading Inhibit Breast Cancer Metastasis in an Orthotopic Murine Model. ACS Appl. Mater. Interfaces, 2022, 14(18), 20551–20565. doi: 10.1021/acsami.1c23737
  115. Chelomin, V. P.; Mazur, A. A.; Slobodskova, V. V.; Kukla, S. P.; Dovzhenko, N. V. Genotoxic Properties of Polystyrene (PS) Microspheres in the Filter-Feeder Mollusk Mytilus Trossulus (Gould, 1850). Journal of Marine Science and Engineering, 2022, 10(2), 273. doi: 10.3390/jmse10020273
  116. Zhao, Y.; Miranda Herrera, P. A.; Chang, D.; Hamelin, R.; Long, M. J. C.; Aye, Y. Function-Guided Proximity Mapping Unveils Electrophilic-Metabolite Sensing by Proteins Not Present in Their Canonical Locales. Proc. Natl. Acad. Sci. U.S.A., 2022, 119(5), e2120687119. doi: 10.1073/pnas.2120687119
  117. Jena, S.; Parker, L. L. Fluorescence Lifetime Imaging Probes for Cell-Based Measurements of Enzyme Activity. Biomedical Engineering Technologies: Methods in Molecular Biology, 2022, 2394, 133–162. doi: 10.1007/978-1-0716-1811-0_9
  118. Valles, M.; Pujals, S.; Albertazzi, L.; Sánchez, S. Enzyme Purification Improves the Enzyme Loading, Self-Propulsion, and Endurance Performance of Micromotors. ACS Nano, 2022, 16(4), 5615–5626. doi: 10.1021/acsnano.1c10520
  119. McGorman, B.; Fantoni, N. Z.; O’Carroll, S.; Ziemele, A.; El-Sagheer, A. H.; Brown, T.; Kellett, A. Enzymatic Synthesis of Chemical Nuclease Triplex-Forming Oligonucleotides with Gene-Silencing Applications. Nucleic Acids Research, 2022, 50(10), 5467–5481. doi: 10.1093/nar/gkac438
  120. Jiang, H.; Chiang, C. Y.; Chen, Z.; Nathan, S.; D’Agostino, G.; Paulo, J. A.; Song, G.; Zhu, H.; Gabelli, S. B.; Cole, P. A. Enzymatic Analysis of WWP2 E3 Ubiquitin Ligase Using Protein Microarrays Identifies Autophagy-Related Substrates. Journal of Biological Chemistry, 2022, 298(5), 101854. doi: 10.1016/j.jbc.2022.101854
  121. Katila, N.; Duwa, R.; Bhurtel, S.; Khanal, S.; Maharjan, S.; Jeong, J.-H.; Lee, S.; Choi, D.-Y.; Yook, S. Enhancement of Blood–Brain Barrier Penetration and the Neuroprotective Effect of Resveratrol. Journal of Controlled Release, 2022, 346, 1–19. doi: 10.1016/j.jconrel.2022.04.003
  122. Chang, Y.; Syahirah, R.; Wang, X.; Jin, G.; Torregrosa-Allen, S.; Elzey, B. D.; Hummel, S. N.; Wang, T.; Li, C.; Lian, X.; Deng, Q.; Broxmeyer, H. E.; Bao, X. Engineering Chimeric Antigen Receptor Neutrophils from Human Pluripotent Stem Cells for Targeted Cancer Immunotherapy. Cell Reports, 2022, 40(3), 111128. doi: 10.1016/j.celrep.2022.111128
  123. Suresh, D.; Suresh, A.; Kannan, R. Engineering Biomolecular Systems: Controlling the Self-Assembly of Gelatin to Form Ultra-Small Bioactive Nanomaterials. Bioactive Materials, 2022, 8, 321–336. doi: 10.1016/j.bioactmat.2022.02.035
  124. Babi, M.; Fatona, A.; Li, X.; Cerson, C.; Jarvis, V. M.; Abitbol, T.; Moran-Mirabal, J. M. Efficient Labeling of Nanocellulose for High-Resolution Fluorescence Microscopy Applications. Biomacromolecules, 2022, 23(5), 1981–1994. doi: 10.1021/acs.biomac.1c01698
  125. Novoselova, M.; Chernyshev, V. S.; Schulga, A.; Konovalova, E. V.; Chuprov-Netochin, R. N.; Abakumova, T. O.; German, S.; Shipunova, V. O.; Mokrousov, M. D.; Prikhozhdenko, E.; Bratashov, D. N.; Nozdriukhin, D. V.; Bogorodskiy, A.; Grishin, O.; Kosolobov, S. S.; Khlebtsov, B. N.; Inozemtseva, O.; Zatsepin, T. S.; Deyev, S. M.; Gorin, D. A. Effect of Surface Modification of Multifunctional Nanocomposite Drug Delivery Carriers with DARPin on Their Biodistribution In Vitro and In Vivo. ACS Appl. Bio Mater., 2022, 5(6), 2976–2989. doi: 10.1021/acsabm.2c00289
  126. Ray, S.; Wirth, D. M.; Ortega-Rivera, O. A.; Steinmetz, N. F.; Pokorski, J. K. Dissolving Microneedle Delivery of a Prophylactic HPV Vaccine. Biomacromolecules, 2022, 23(3), 903–912. doi: 10.1021/acs.biomac.1c01345
  127. Olson, S. W.; Turner, A.-M. W.; Arney, J. W.; Saleem, I.; Weidmann, C. A.; Margolis, D. M.; Weeks, K. M.; Mustoe, A. M. Discovery of a Large-Scale, Cell-State-Responsive Allosteric Switch in the 7SK RNA Using DANCE-MaP. Molecular Cell, 2022, 82(9), 1708-1723.e10. doi: 10.1016/j.molcel.2022.02.009
  128. Babi, M.; Palermo, A.; Abitbol, T.; Fatona, A.; Jarvis, V.; Nayak, A.; Cranston, E.; Moran-Mirabal, J. Direct Imaging of the Alternating Disordered and Crystalline Structure of Cellulose Fibrils via Super-Resolution Fluorescence Microscopy. ChemRxiv, 2022, preprint. doi: 10.26434/chemrxiv-2022-0jqng
  129. Chen, Y.; Wang, Y.; Jiang, X.; Cai, J.; Chen, Y.; Huang, H.; Yang, Y.; Zheng, L.; Zhao, J.; Gao, M. Dimethylamino Group Modified Polydopamine Nanoparticles with Positive Charges to Scavenge Cell-Free DNA for Rheumatoid Arthritis Therapy. Bioactive Materials, 2022, 18, 409–420. doi: 10.1016/j.bioactmat.2022.03.028
  130. Bieber, J. M.; Sanman, L. E.; Sun, X.; Hammerlindl, H.; Bao, F.; Roth, M. A.; Koleske, M. L.; Huang, L.; Aweeka, F.; Wu, L. F.; Altschuler, S. J. Differential Toxicity to Murine Small and Large Intestinal Epithelium Induced by Oncology Drugs. Commun Biol, 2022, 5(1), 1–11. doi: 10.1038/s42003-022-03048-x
  131. Bessonova, T. A.; Fando, M. S.; Kostareva, O. S.; Tutukina, M. N.; Ozoline, O. N.; Gelfand, M. S.; Nikulin, A. D.; Tishchenko, S. V. Differential Impact of Hexuronate Regulators ExuR and UxuR on the Escherichia Coli Proteome. International Journal of Molecular Sciences, 2022, 23(15), 8379. doi: 10.3390/ijms23158379
  132. Matoori, S.; Mooney, D. J. Development of a Liposomal Near-Infrared Fluorescence Lactate Assay for Human Blood. Biomaterials, 2022, 283, 121475. doi: 10.1016/j.biomaterials.2022.121475
  133. Marasini, N.; Er, G.; Fu, C.; Subasic, C. N.; Ibrahim, J.; Skwarczynski, M.; Toth, I.; Whittaker, A. K.; Kaminskas, L. M. Development of a Hyperbranched Polymer-Based Methotrexate Nanomedicine for Rheumatoid Arthritis. Acta Biomaterialia, 2022, 142, 298–307. doi: 10.1016/j.actbio.2022.01.054.
  134. Ryabchevskaya, E. M.; Granovskiy, D. L.; Evtushenko, E. A.; Ivanov, P. A.; Kondakova, O. A.; Nikitin, N. A.; Karpova, O. V. Designing Stable Bacillus Anthracis Antigens with a View to Recombinant Anthrax Vaccine Development. Pharmaceutics, 2022, 14(4), 806. doi: 10.3390/pharmaceutics14040806
  135. Demina, P. A.; Saveleva, M. S.; Anisimov, R. A.; Prikhozhdenko, E. S.; Voronin, D. V.; Abalymov, A. A.; Cherednichenko, K. A.; Timaeva, O. I.; Lomova, M. V. Degradation of Hybrid Drug Delivery Carriers with a Mineral Core and a Protein–Tannin Shell under Proteolytic Hydrolases. Biomimetics, 2022, 7(2), 61. doi: 10.3390/biomimetics7020061
  136. Tsavkelova, E. A.; Glukhareva, I. D.; Volynchikova, E. A.; Egorova, M. A.; Leontieva, M. R.; Malakhova, D. V.; Kolomeitseva, G. L.; Netrusov, A. I. Cyanobacterial Root Associations of Leafless Epiphytic Orchids. Microorganisms, 2022, 10(5), 1006. doi: 10.3390/microorganisms10051006
  137. Garafutdinov, R. R.; Chemeris, D. A.; Sakhabutdinova, A. R.; Moiseev, K. V.; Urmancheev, S. F.; Mikhaylenko, C. I.; Privalov, L. Y.; Chemeris, A. V. Convective Polymerase Chain Reaction in Standard Microtubes. Analytical Biochemistry, 2022, 641, 114565. doi: 10.1016/j.ab.2022.114565
  138. Zivotska, H.; Mokry, M.; Rodrigo, M. A. M.; Michalkova, H.; Kapolkova, K.; Splichal, Z.; Stokowa-Soltys, K.; Milosavljevic, V.; Guran, R.; Richtera, L.; Haddad, Y.; Rex, S.; Heger, Z. Conotoxin-Derived Biomimetic Coiled Cone-Shaped Peptide as Ligand for Selective Nanodelivery to Norepinephrine Transporter-Expressing Neuroblastoma Cells. Applied Materials Today, 2022, 27, 101410. doi: 10.1016/j.apmt.2022.101410
  139. Konhäuser, M.; Kannaujiya, V. K.; Steiert, E.; Schwickert, K.; Schirmeister, T.; Wich, P. R. Co-Encapsulation of l-Asparaginase and Etoposide in Dextran Nanoparticles for Synergistic Effect in Chronic Myeloid Leukemia Cells. International Journal of Pharmaceutics, 2022, 622, 121796. doi: 10.1016/j.ijpharm.2022.121796
  140. Hanisch, D.; Krumm, A.; Diehl, T.; Stork, C. M.; Dejung, M.; Butter, F.; Kim, E.; Brenner, W.; Fritz, G.; Hofmann, T. G.; Roos, W. P. Class I HDAC Overexpression Promotes Temozolomide Resistance in Glioma Cells by Regulating RAD18 Expression. Cell Death Dis, 2022, 13(4), 1–12. doi: 10.1038/s41419-022-04751-7
  141. Kolyvanova, M. A.; Klimovich, M. A.; Shibaeva, A. V.; Koshevaya, E. D.; Bushmanov, Y. A.; Belousov, A. V.; Kuzmin, V. A.; Morozov, V. N. Cholesteric Liquid-Crystalline DNA – a New Type of Chemical Detector of Ionizing Radiation. Liquid Crystals, 2022, 49(10), 1359–1366. doi: 10.1080/02678292.2022.2032854
  142. Lin, G.; Huang, J.; Zhang, M.; Chen, S.; Zhang, M. Chitosan-Crosslinked Low Molecular Weight PEI-Conjugated Iron Oxide Nanoparticle for Safe and Effective DNA Delivery to Breast Cancer Cells. Nanomaterials, 2022, 12(4), 584. doi: 10.3390/nano12040584
  143. Perzanowska, O.; Smietanski, M.; Jemielity, J.; Kowalska, J. Chemically Modified Poly(A) Analogs Targeting PABP: Structure Activity Relationship and Translation Inhibitory Properties. Chemistry – A European Journal, 2022, 28(42), e202201115. doi: 10.1002/chem.202201115
  144. Piranej, S.; Bazrafshan, A.; Salaita, K. Chemical-to-Mechanical Molecular Computation Using DNA-Based Motors with Onboard Logic. Nat. Nanotechnol., 2022, 17(5), 514–523. doi: 10.1038/s41565-022-01080-w
  145. Ahunbay, E.; Steffen, F. D.; Zelger-Paulus, S.; Sigel, R. K. O. Chemical Dual End-Labeling of Large Ribozymes. DNAzymes: Methods and Protocols, 2022, 2439, 191–204. doi: 10.1007/978-1-0716-2047-2_13
  146. Fouquet, J. P.; Sikpa, D.; Lebel, R.; Sibgatulin, R.; Krämer, M.; Herrmann, K.-H.; Deistung, A.; Tremblay, L.; Reichenbach, J. R.; Lepage, M. Characterization of Microparticles of Iron Oxide for Magnetic Resonance Imaging. Magnetic Resonance Imaging, 2022, 92, 67–81. doi: 10.1016/j.mri.2022.05.020
  147. Ramm, F.; Jack, L.; Kaser, D.; Schloßhauer, J. L.; Zemella, A.; Kubick, S. Cell-Free Systems Enable the Production of AB5 Toxins for Diagnostic Applications. Toxins, 2022, 14(4), 233. doi: 10.3390/toxins14040233
  148. Ksenofontov, A. A.; Lukanov, M. M.; Bocharov, P. S. Can Machine Learning Methods Accurately Predict the Molar Absorption Coefficient of Different Classes of Dyes?. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 279, 121442. doi: 10.1016/j.saa.2022.121442
  149. Zeng, L.; Liu, Y.; Nguyenla, X. H.; Abbott, T. R.; Han, M.; Zhu, Y.; Chemparathy, A.; Lin, X.; Chen, X.; Wang, H.; Rane, D. A.; Spatz, J. M.; Jain, S.; Rustagi, A.; Pinsky, B.; Zepeda, A. E.; Kadina, A. P.; Walker, J. A.; Holden, K.; Temperton, N.; Cochran, J. R.; Barron, A. E.; Connolly, M. D.; Blish, C. A.; Lewis, D. B.; Stanley, S. A.; La Russa, M. F.; Qi, L. S. Broad-Spectrum CRISPR-Mediated Inhibition of SARS-CoV-2 Variants and Endemic Coronaviruses in Vitro. Nat Commun, 2022, 13(1), 2766. doi: 10.1038/s41467-022-30546-7
  150. Yu, H.; Palazzolo, J. S.; Zhou, J.; Hu, Y.; Niego, B.; Pan, S.; Ju, Y.; Wang, T.-Y.; Lin, Z.; Hagemeyer, C. E.; Caruso, F. Bioresponsive Polyphenol-Based Nanoparticles as Thrombolytic Drug Carriers. ACS Appl. Mater. Interfaces, 2022, 14(3), 3740–3751. doi: 10.1021/acsami.1c19820
  151. Hayun, H.; Arkadash, V.; Sananes, A.; Arbely, E.; Stepensky, D.; Papo, N. Bioorthogonal PEGylation Prolongs the Elimination Half-Life of N-TIMP2 While Retaining MMP Inhibition. Bioconjugate Chem., 2022, 33(5), 795–806. doi: 10.1021/acs.bioconjchem.2c00059
  152. Li, S.; Co, C. M.; Izuagbe, S.; Hong, Y.; Liao, J.; Borrelli Jr., J.; Tang, L. Biomolecules-Releasing Click Chemistry-Based Bioadhesives for Repairing Acetabular Labrum Tears. Journal of Orthopaedic Research, 2022, 40(11), 2646–2655. doi: 10.1002/jor.25290
  153. Tengjisi; Liu, Y.; Zou, D.; Yang, G.; Zhao, C.-X. Bioinspired Core-Shell Silica Nanoparticles Monitoring Extra- and Intra-Cellular Drug Release. Journal of Colloid and Interface Science, 2022, 624, 242–250. doi: 10.1016/j.jcis.2022.05.099
  154. de Paiva, I. M.; Vakili, M. R.; Soleimani, A. H.; Tabatabaei Dakhili, S. A.; Munira, S.; Paladino, M.; Martin, G.; Jirik, F. R.; Hall, D. G.; Weinfeld, M.; Lavasanifar, A. Biodistribution and Activity of EGFR Targeted Polymeric Micelles Delivering a New Inhibitor of DNA Repair to Orthotopic Colorectal Cancer Xenografts with Metastasis. Mol. Pharmaceutics, 2022, 19(6), 1825–1838. doi: 10.1021/acs.molpharmaceut.1c00918
  155. de Jesus, V.; Schmid, J.; Fürtig, B. Binding of 30S Ribosome Induces Single-Stranded Conformation Within and Downstream of the Expression Platform in a Translational Riboswitch. Journal of Molecular Biology, 2022, 434(18), 167668. doi: 10.1016/j.jmb.2022.167668
  156. Białas, N.; Sokolova, V.; van der Meer, S. B.; Knuschke, T.; Ruks, T.; Klein, K.; Westendorf, A. M.; Epple, M. Bacteria (E. Coli) Take up Ultrasmall Gold Nanoparticles (2 Nm) as Shown by Different Optical Microscopic Techniques (CLSM, SIM, STORM). Nano Select, 2022, 3(10), 1407–1420. doi: 10.1002/nano.202200049
  157. Lella, M.; Oh, M. W.; Kuo, S. H.; Lau, G. W.; Tal-Gan, Y. Attenuating the Streptococcus Pneumoniae Competence Regulon Using Urea-Bridged Cyclic Dominant-Negative Competence-Stimulating Peptide Analogs. J. Med. Chem., 2022, 65(9), 6826–6839. doi: 10.1021/acs.jmedchem.2c00148
  158. Gaikwad, H.; Li, Y.; Wang, G.; Li, R.; Dai, S.; Rester, C.; Kedl, R.; Saba, L.; Banda, N. K.; Scheinman, R. I.; Patrick, C.; Mallela, K. M. G.; Moghimi, S. M.; Simberg, D. Antibody-Dependent Complement Responses toward SARS-CoV-2 Receptor-Binding Domain Immobilized on “Pseudovirus-like” Nanoparticles. ACS Nano, 2022, 16(6), 8704–8715. doi: 10.1021/acsnano.2c02794
  159. Zheng, J.; Hu, R.; Yang, Y.; Wang, Y.; Wang, Q.; Xu, S.; Yao, P.; Liu, Z.; Zhou, J.; Yang, J.; Bao, Y.; Zhang, D.; Shen, W.; Zhou, Z. Antibiotic-Loaded Reactive Oxygen Species-Responsive Nanomedicine for Effective Management of Chronic Bacterial Prostatitis. Acta Biomaterialia, 2022, 143, 471–486. doi: 10.1016/j.actbio.2022.02.044
  160. Wu, D.; Wang, Z.; Huang, J.; Huang, L.; Zhang, S.; Zhao, R.; Li, W.; Chen, D.; Ou, G. An Antagonistic Pleiotropic Gene Regulates the Reproduction and Longevity Tradeoff. Proceedings of the National Academy of Sciences, 2022, 119(18), e2120311119. doi: 10.1073/pnas.2120311119
  161. Osipova, O.; Zakharova, N.; Pyankov, I.; Egorova, A.; Kislova, A.; Lavrentieva, A.; Kiselev, A.; Tennikova, T.; Korzhikova-Vlakh, E. Amphiphilic PH-Sensitive Polypeptides for SiRNA Delivery. Journal of Drug Delivery Science and Technology, 2022, 69, 103135. doi: 10.1016/j.jddst.2022.103135
  162. Mitrach, F.; Schmid, M.; Toussaint, M.; Dukic-Stefanovic, S.; Deuther-Conrad, W.; Franke, H.; Ewe, A.; Aigner, A.; Wölk, C.; Brust, P.; Hacker, M. C.; Schulz-Siegmund, M. Amphiphilic Anionic Oligomer-Stabilized Calcium Phosphate Nanoparticles with Prospects in SiRNA Delivery via Convection-Enhanced Delivery. Pharmaceutics, 2022, 14(2), 326. doi: 10.3390/pharmaceutics14020326
  163. Hong, S.-N.; Kim, M.; Park, J.-A.; Kang, M.; Cha, H.; Park, S.; Kim, J. K.; Pac, J.; Seo, Y.; Kim, S.; Kim, M.; Kim, D. W.; Lee, Y. Alleviation of Surgery-Induced Osteitis in Sinonasal Cavity by Dexamethasone-Loaded Poly(Lactic-Co-Glycolic Acid) (PLGA) Microparticles with Strong Calcium-Binding Affinity. Pharmaceutics, 2022, 14(3), 546. doi: 10.3390/pharmaceutics14030546
  164. Dinesen, A.; Winther, A.; Wall, A.; Märcher, A.; Palmfeldt, J.; Chudasama, V.; Wengel, J.; Gothelf, K. V.; Baker, J. R.; Howard, K. A. Albumin Biomolecular Drug Designs Stabilized through Improved Thiol Conjugation and a Modular Locked Nucleic Acid Functionalized Assembly. Bioconjugate Chem., 2022, 33(2), 333–342. doi: 10.1021/acs.bioconjchem.1c00561
  165. Edr, A.; Wrobel, D.; Krupková, A.; Šťastná, L. Č.; Cuřínová, P.; Novák, A.; Malý, J.; Kalasová, J.; Malý, J.; Malý, M.; Strašák, T. Adaptive Synthesis of Functional Amphiphilic Dendrons as a Novel Approach to Artificial Supramolecular Objects. International Journal of Molecular Sciences, 2022, 23(4), 2114. doi: 10.3390/ijms23042114
  166. Lee, J. Y.; Wing, P. A.; Gala, D. S.; Noerenberg, M.; Järvelin, A. I.; Titlow, J.; Zhuang, X.; Palmalux, N.; Iselin, L.; Thompson, M. K.; Parton, R. M.; Prange-Barczynska, M.; Wainman, A.; Salguero, F. J.; Bishop, T.; Agranoff, D.; James, W.; Castello, A.; McKeating, J. A.; Davis, I. Absolute Quantitation of Individual SARS-CoV-2 RNA Molecules Provides a New Paradigm for Infection Dynamics and Variant Differences. eLife, 2022, 11, e74153. doi: 10.7554/eLife.74153
  167. Cheng, B.; Ahn, H.-H.; Nam, H.; Jiang, Z.; Gao, F. J.; Minn, I.; Pomper, M. G. A Unique Core–Shell Structured, Glycol Chitosan-Based Nanoparticle Achieves Cancer-Selective Gene Delivery with Reduced Off-Target Effects. Pharmaceutics, 2022, 14(2), 373. doi: 10.3390/pharmaceutics14020373
  168. Dai, Z.; Wang, Q.; Tang, J.; Qu, R.; Wu, M.; Li, H.; Yang, Y.; Zhen, X.; Yu, C. A Sub-6 Nm MnFe2O4-Dichloroacetic Acid Nanocomposite Modulates Tumor Metabolism and Catabolism for Reversing Tumor Immunosuppressive Microenvironment and Boosting Immunotherapy. Biomaterials, 2022, 284, 121533. doi: 10.1016/j.biomaterials.2022.121533
  169. Lin, C.-H.; Sun, Y. J.; Lee, S. H.; Mujica, E. M.; Kunchur, C. R.; Wu, M.-R.; Yang, J.; Jung, Y. S.; Chiang, B.; Wang, S.; Mahajan, V. B. A Protocol to Inject Ocular Drug Implants into Mouse Eyes. STAR Protocols, 2022, 3(1), 101143. doi: 10.1016/j.xpro.2022.101143
  170. Kim, R.; Wang, Y.; Sims, C. E.; Allbritton, N. L. A Platform for Co-Culture of Primary Human Colonic Epithelium With Anaerobic Probiotic Bacteria. Front Bioeng Biotechnol, 2022, 10, 890396. doi: 10.3389/fbioe.2022.890396
  171. Fujii, S.; Sakurai, K. Zwitterionic Amino Acid Polymer-Grafted Core-Crosslinked Particle toward Tumor Delivery. Biomacromolecules, 2022, 23(9), 3968–3977. doi: 10.1021/acs.biomac.2c00803
  172. Xu, J.; Zhang, Y.; Liu, Y.; You, Y.; Li, F.; Chen, Y.; Xie, L.; Tong, S.; Zhou, S.; Liang, K.; Huang, Y.; Jiang, G.; Song, Q.; Mei, N.; Ma, F.; Gao, X.; Wang, H.; Chen, J. Vitality-Enhanced Dual-Modal Tracking System Reveals the Dynamic Fate of Mesenchymal Stem Cells for Stroke Therapy. Small, 2022, 18(47), 2203431. doi: 10.1002/smll.202203431
  173. Mitmoen, M.; Kedem, O. UV- and Visible-Light Photopatterning of Molecular Gradients Using the Thiol–Yne Click Reaction. ACS Appl. Mater. Interfaces, 2022, 14(28), 32696–32705. doi: 10.1021/acsami.2c06946.
  174. Lee, W. Y.; Chapman, D. V.; Yu, F.; Tait, W. R. T.; Thedford, R. P.; Freychet, G.; Zhernenkov, M.; Estroff, L. A.; Wiesner, U. B. Triblock Terpolymer Thin Film Nanocomposites Enabling Two-Color Optical Super-Resolution Microscopy. Macromolecules, 2022, 55(21), 9452–9464. doi: 10.1021/acs.macromol.2c01017
  175. Lee, W. Y.; Chapman, D. V.; Yu, F.; Tait, W. R. T.; Thedford, R. P.; Freychet, G.; Zhernenkov, M.; Estroff, L. A.; Wiesner, U. B. Triblock Terpolymer Thin Film Nanocomposites Enabling Two-Color Optical Super-Resolution Microscopy. Macromolecules, 2022, 55(21), 9452–9464. doi: 10.1021/acs.macromol.2c01017
  176. Liao, F.-H.; Yao, C.-N.; Chen, S.-P.; Wu, T.-H.; Lin, S.-Y. Transdermal Delivery of Succinate Accelerates Energy Dissipation of Brown Adipocytes to Reduce Remote Fat Accumulation. Mol. Pharmaceutics, 2022, 19(11), 4299–4310. doi: 10.1021/acs.molpharmaceut.2c00628
  177. Wang, Z.; He, Y.; Tan, Z. Transcription Analysis of Liver and Muscle Tissues from Landrace Finishing Pigs with Different Feed Conversion Ratios. Genes, 2022, 13(11), 2067. doi: 10.3390/genes13112067
  178. Ghaffari Sharaf, M.; Waduthanthri, K. D.; Crichton, A.; Damji, K. F.; Unsworth, L. D. Towards Preventing Exfoliation Glaucoma by Targeting and Removing Fibrillar Aggregates Associated with Exfoliation Syndrome. Journal of Nanobiotechnology, 2022, 20(1), 459. doi: 10.1186/s12951-022-01665-6
  179. Mai, Y.; Ouyang, Y.; Yu, M.; Qin, Y.; Girardi, M.; Saltzman, W. M.; Cocco, E.; Zhao, C.; Yu, L.; Jia, Y.; Xiao, L.; Dou, L.; Deng, W.; Liu, Y.; Xie, J.; Deng, Y. Topical Formulation Based on Disease-Specific Nanoparticles for Single-Dose Cure of Psoriasis. Journal of Controlled Release, 2022, 349, 354–366. doi: 10.1016/j.jconrel.2022.07.006
  180. Alexandrova, V. V.; Anisimov, M. N.; Zaitsev, A. V.; Mustyatsa, V. V.; Popov, V. V.; Ataullakhanov, F. I.; Gudimchuk, N. B. Theory of Tip Structure–Dependent Microtubule Catastrophes and Damage-Induced Microtubule Rescues. Proceedings of the National Academy of Sciences, 2022, 119(46), e2208294119. doi: 10.1073/pnas.2208294119
  181. Senchurova, S. I.; Syryamina, V. N.; Kuznetsova, A. A.; Novopashina, D. S.; Ishchenko, A. A.; Saparbaev, M.; Dzuba, S. A.; Fedorova, O. S.; Kuznetsov, N. A. The Mechanism of Damage Recognition by Apurinic/Apyrimidinic Endonuclease Nfo from Escherichia Coli. Biochimica et Biophysica Acta (BBA) - General Subjects, 2022, 1866(11), 130216. doi: 10.1016/j.bbagen.2022.130216
  182. Cuccaro, A.; De Marchi, L.; Oliva, M.; Monni, G.; Miragliotta, V.; Fumagalli, G.; Freitas, R.; Pretti, C. The Influence of Salinity on the Toxicity of Chemical UV-Filters to Sperms of the Free-Spawning Mussel Mytilus Galloprovincialis (Lamark, 1819). Aquatic Toxicology, 2022, 250, 106263. doi: 10.1016/j.aquatox.2022.106263
  183. Kuiper, E. F. E.; Gallardo, P.; Bergsma, T.; Mari, M.; Kolbe Musskopf, M.; Kuipers, J.; Giepmans, B. N. G.; Steen, A.; Kampinga, H. H.; Veenhoff, L. M.; Bergink, S. The Chaperone DNAJB6 Surveils FG-Nucleoporins and Is Required for Interphase Nuclear Pore Complex Biogenesis. Nat Cell Biol, 2022, 24(11), 1584–1594. doi: 10.1038/s41556-022-01010-x
  184. Duwa, R.; Pokhrel, R. H.; Banstola, A.; Pandit, M.; Shrestha, P.; Jeong, J.-H.; Chang, J.-H.; Yook, S. T-Cell Engaging Poly(Lactic-Co-Glycolic Acid) Nanoparticles as a Modular Platform to Induce a Potent Cytotoxic Immunogenic Response against PD-L1 Overexpressing Cancer. Biomaterials, 2022, 291, 121911. doi: 10.1016/j.biomaterials.2022.121911
  185. Liu, L.; Pan, D.; Chen, S.; Martikainen, M.-V.; Kårlund, A.; Ke, J.; Pulkkinen, H.; Ruhanen, H.; Roponen, M.; Käkelä, R.; Xu, W.; Wang, J.; Lehto, V.-P. Systematic Design of Cell Membrane Coating to Improve Tumor Targeting of Nanoparticles. Nat Commun, 2022, 13(1), 6181. doi: 10.1038/s41467-022-33889-3
  186. Terekhova, N. V.; Lyubina, A. P.; Voloshina, A. D.; Sapunova, A. S.; Khayarov, K. R.; Islamov, D. R.; Usachev, K. S.; Evtugyn, V. G.; Tatarinov, D. A.; Mironov, V. F. Synthesis, Biological Evaluation and Structure-Activity Relationship of 2-(2-Hydroxyaryl)Alkenylphosphonium Salts with Potency as Anti-MRSA Agents. Bioorganic Chemistry, 2022, 127, 106030. doi: 10.1016/j.bioorg.2022.106030
  187. Salazar-Chaparro, A. F.; Halder, S.; Trader, D. J. Synthesis and Application of a Clickable Epoxomicin-Based Probe for Proteasome Activity Analysis. Current Protocols, 2022, 2(7), e490. doi: 10.1002/cpz1.490
  188. Deiss-Yehiely, E.; Brucks, S. D.; Boehnke, N.; Pickering, A. J.; Kiessling, L. L.; Hammond, P. T. Surface Presentation of Hyaluronic Acid Modulates Nanoparticle–Cell Association. Bioconjugate Chem., 2022, 33(11), 2065–2075. doi: 10.1021/acs.bioconjchem.2c00412
  189. Shen, N.; Qi, X.; Bagrov, D. V.; Krechetov, S. P.; Sharapov, M. G.; Durymanov, M. O. Surface Modification of Fibroblasts with Peroxiredoxin-1-Loaded Polymeric Microparticles Increases Cell Mobility, Resistance to Oxidative Stress and Collagen I Production. Colloids and Surfaces B: Biointerfaces, 2022, 219, 112834. doi: 10.1016/j.colsurfb.2022.112834
  190. Judge, R. A.; Sridar, J.; Tunyasuvunakool, K.; Jain, R.; Wang, J. C. K.; Ouch, C.; Xu, J.; Mafi, A.; Nile, A. H.; Remarcik, C.; Smith, C. L.; Ghosh, C.; Xu, C.; Stoll, V.; Jumper, J.; Singh, A. H.; Eaton, D.; Hao, Q. Structure of the PAPP-ABP5 Complex Reveals Mechanism of Substrate Recognition. Nat Commun, 2022, 13(1), 5500. doi: 10.1038/s41467-022-33175-2
  191. Zhou, X.; Sala, G.; Sagis, L. M. C. Structure and Rheological Properties of Oil-Water and Air-Water Interfaces Stabilized with Micellar Casein Isolate and Whey Protein Isolate Mixtures. Food Hydrocolloids, 2022, 133, 107946. doi: 10.1016/j.foodhyd.2022.107946
  192. Kapitonova, A. A.; Tugaeva, K. V.; Varfolomeeva, L. A.; Boyko, K. M.; Cooley, R. B.; Sluchanko, N. N. Structural Basis for the Recognition by 14-3-3 Proteins of a Conditional Binding Site within the Oligomerization Domain of Human Nucleophosmin. Biochemical and Biophysical Research Communications, 2022, 627, 176–183. doi: 10.1016/j.bbrc.2022.08.047
  193. Zavyalova, E.; Tikhonova, D.; Zhdanov, G.; Rudakova, E.; Alferova, V.; Moiseenko, A.; Kamzeeva, P.; Khrulev, A.; Zalevsky, A.; Arutyunyan, A.; Novikov, R.; Kukushkin, V.; Aralov, A. SERS-Based Biosensor with Raman-Active External Responsive Element for Rapid Determination of Adenosine Monophosphate. Analytica Chimica Acta, 2022, 1221, 340140. doi: 10.1016/j.aca.2022.340140
  194. DiSalvo, M.; Patrone, P. N.; Kearsley, A. J.; Cooksey, G. A. Serial Flow Cytometry in an Inertial Focusing Optofluidic Microchip for Direct Assessment of Measurement Variations. Lab Chip, 2022, 22(17), 3217–3228. doi: 10.1039/D1LC01169C
  195. Ge, X.; Hao, Y.; Li, H.; Zhao, H.; Liu, Y.; Liu, Y.; Li, X.; Chen, H.; Zou, J.; Zhang, S.; Huang, L.; Shan, G.; Zhang, Z. Sequential Acid/Reduction Response of Triblock Copolymeric Nanomicelles to Release Camptothecin and Toll-like Receptor 7/8 Agonist for Orchestrated Chemoimmunotherapy. Journal of Nanobiotechnology, 2022, 20(1), 369. doi: 10.1186/s12951-022-01577-5
  196. McMullen, A.; Muñoz Basagoiti, M.; Zeravcic, Z.; Brujic, J. Self-Assembly of Emulsion Droplets through Programmable Folding. Nature, 2022, 610(7932), 502–506. doi: 10.1038/s41586-022-05198-8
  197. Klimek, R.; Kaiser, C.; Murmann, N. S.; Kaltenschnee, N.; Spanò, T.; Wachtveitl, J.; Schuman, E. M.; Heckel, A. RNA Probes for Visualization of Sarcin/Ricin Loop Depurination without Background Fluorescence. Chemistry – An Asian Journal, 2022, 17(24), e202201077. doi: 10.1002/asia.202201077
  198. Gallicano, G. I.; Fu, J.; Mahapatra, S.; Sharma, M. V. R.; Dillon, C.; Deng, C.; Zahid, M. Reversing Cardiac Hypertrophy at the Source Using a Cardiac Targeting Peptide Linked to MiRNA106a: Targeting Genes That Cause Cardiac Hypertrophy. Pharmaceuticals, 2022, 15(7), 871. doi: 10.3390/ph15070871
  199. Sakhabutdinova, A. R.; Gazizov, R. R.; Chemeris, A. V.; Garafutdinov, R. R. Reverse Transcriptase-Free Detection of Viral RNA Using Hemo Klentaq DNA Polymerase. Analytical Biochemistry, 2022, 659, 114960.. doi: 10.1016/j.ab.2022.114960
  200. Chattaraj, R.; Kim, C. Y.; Lee, D.; Hammer, D. A. Recombinant Protein Micelles to Block Transduction by SARS-CoV-2 Pseudovirus. ACS Nano, 2022, 16(10), 17466–17477. doi: 10.1021/acsnano.2c09015
  201. Wang, P.; Moreno, S.; Janke, A.; Boye, S.; Wang, D.; Schwarz, S.; Voit, B.; Appelhans, D. Probing Crowdedness of Artificial Organelles by Clustering Polymersomes for Spatially Controlled and PH-Triggered Enzymatic Reactions. Biomacromolecules, 2022, 23(9), 3648–3662. doi: 10.1021/acs.biomac.2c00546
  202. Tang, Y.-J.; Zhou, D.-Y.; Dai, J.; Li, Y.; Xing, Y.-M.; Guo, S.-X.; Chen, J. Potential Specificity Between Mycorrhizal Fungi Isolated from Widespread Dendrobium Spp. and Rare D. Huoshanense Seeds. Curr Microbiol, 2022, 79(9), 264. doi: 10.1007/s00284-022-02952-z
  203. Hagen, R.; Fehr, D.; Spano, F.; Brambilla, D.; Bonmarin, M. Portable Multi-Wavelength Fluorescence Measurement Device. 2022 IEEE International Symposium on Medical Measurements and Applications (MeMeA), 2022, 1-6. doi: 10.1109/MeMeA54994.2022.9856591
  204. Jeong, M.; Jung, Y.; Yoon, J.; Kang, J.; Lee, S. H.; Back, W.; Kim, H.; Sailor, M. J.; Kim, D.; Park, J.-H. Porous Silicon-Based Nanomedicine for Simultaneous Management of Joint Inflammation and Bone Erosion in Rheumatoid Arthritis. ACS Nano, 2022, 16(10), 16118–16132. doi: 10.1021/acsnano.2c04491.
  205. Yu, H.; Palazzolo, J. S.; Ju, Y.; Niego, B.; Pan, S.; Hagemeyer, C. E.; Caruso, F. Polyphenol-Functionalized Cubosomes as Thrombolytic Drug Carriers. Advanced Healthcare Materials, 2022, 11(21), 2201151. doi: 10.1002/adhm.202201151
  206. Hu, Y.; Wang, Y.; Singh, J.; Sun, R.; Xu, L.; Niu, X.; Huang, K.; Bai, G.; Liu, G.; Zuo, X.; Chen, C.; Qin, P. Z.; Fang, X. Phosphorothioate-Based Site-Specific Labeling of Large RNAs for Structural and Dynamic Studies. ACS Chem. Biol., 2022, 17(9), 2448–2460. doi: 10.1021/acschembio.2c00199
  207. Cathcart, J.; Suarato, G.; Li, W.; Cao, J.; Meng, Y. Peptide-Functionalized Nanoparticles for the Targeted Delivery of Cytotoxins to MMP-14-Expressing Cancer Cells. Biophysica, 2022, 2(3), 203–220. doi: 10.3390/biophysica2030021
  208. Almeida, S. F. F.; Fonseca, A.; Sereno, J.; Ferreira, H. R. S.; Lapo-Pais, M.; Martins-Marques, T.; Rodrigues, T.; Oliveira, R. C.; Miranda, C.; Almeida, L. P.; Girão, H.; Falcão, A.; Abrunhosa, A. J.; Gomes, C. M. Osteosarcoma-Derived Exosomes as Potential PET Imaging Nanocarriers for Lung Metastasis. Small, 2022, 18(49), 2203999. doi: 10.1002/smll.202203999
  209. Almeida, A.; Castro, F.; Resende, C.; Lúcio, M.; Schwartz, S.; Sarmento, B. Oral Delivery of Camptothecin-Loaded Multifunctional Chitosan-Based Micelles Is Effective in Reduce Colorectal Cancer. Journal of Controlled Release, 2022, 349, 731–743. doi: 10.1016/j.jconrel.2022.07.029
  210. Chen, Y.; Wang, Y.; Chen, Z.; Cai, J.; Li, K.; Huang, H.; Song, F.; Gao, M.; Yang, Y.; Zheng, L.; Zhao, J. NIR-Driven Polydopamine-Based Nanoenzymes as ROS Scavengers to Suppress Osteoarthritis Progression. Materials Today Nano, 2022, 19, 100240. doi: 10.1016/j.mtnano.2022.100240
  211. Zhang, F.; Zhuang, J.; Li, Z.; Gong, H.; de Ávila, B. E.-F.; Duan, Y.; Zhang, Q.; Zhou, J.; Yin, L.; Karshalev, E.; Gao, W.; Nizet, V.; Fang, R. H.; Zhang, L.; Wang, J. Nanoparticle-Modified Microrobots for in Vivo Antibiotic Delivery to Treat Acute Bacterial Pneumonia. Nat. Mater., 2022, 21(11), 1324–1332. doi: 10.1038/s41563-022-01360-9
  212. Liu, H.; Wen, Z.; Chen, H.; Yang, Z.; Le, Z.; Liu, Z.; Chen, Y.; Liu, L. Nanoadjuvants Actively Targeting Lymph Node Conduits and Blocking Tumor Invasion in Lymphatic Vessels. Journal of Controlled Release, 2022, 352, 497–506. doi: 0.1016/j.jconrel.2022.10.053
  213. Mills, C. E.; Subramanian, K.; Hafner, M.; Niepel, M.; Gerosa, L.; Chung, M.; Victor, C.; Gaudio, B.; Yapp, C.; Nirmal, A. J.; Clark, N.; Sorger, P. K. Multiplexed and Reproducible High Content Screening of Live and Fixed Cells Using Dye Drop. Nature Communications, 2022, 13(1), 6918. doi: 10.1038/s41467-022-34536-7
  214. Zhang, Y.; Sriramaneni, R. N.; Clark, P. A.; Jagodinsky, J. C.; Ye, M.; Jin, W.; Wang, Y.; Bates, A.; Kerr, C. P.; Le, T.; Allawi, R.; Wang, X.; Xie, R.; Havighurst, T. C.; Chakravarty, I.; Rakhmilevich, A. L.; O’Leary, K. A.; Schuler, L. A.; Sondel, P. M.; Kim, K.; Gong, S.; Morris, Z. S. Multifunctional Nanoparticle Potentiates the in Situ Vaccination Effect of Radiation Therapy and Enhances Response to Immune Checkpoint Blockade. Nat Commun, 2022, 13(1), 4948. doi: 10.1038/s41467-022-32645-x
  215. Semenova, D.; Zabirnyk, A.; Lobov, A.; Boyarskaya, N.; Kachanova, O.; Uspensky, V.; Zainullina, B.; Denisov, E.; Gerashchenko, T.; Kvitting, J.-P. E.; Kaljusto, M.-L.; Thiede, B.; Kostareva, A.; Stensløkken, K.-O.; Vaage, J.; Malashicheva, A. Multi-Omics of in Vitro Aortic Valve Calcification. Frontiers in Cardiovascular Medicine, 2022, 9, 1043165. doi: 10.3389/fcvm.2022.1043165
  216. New, E. J. Molecular Fluorescent Sensors for Cellular Studies. John Wiley & Sons, 2022
  217. Luu, B. E.; Mossa, A. H.; Cammisotto, P. G.; Uri Saragovi, H.; Campeau, L. Modulation of Diabetic Kidney Disease Markers by an Antagonist of P75NTR in Streptozotocin-Treated Mice. Gene, 2022, 838, 146729. doi: 10.1016/j.gene.2022.146729
  218. Mills, J. A.; Humphries, J.; Simpson, J. D.; Sonderegger, S. E.; Thurecht, K. J.; Fletcher, N. L. Modulating Macrophage Clearance of Nanoparticles: Comparison of Small-Molecule and Biologic Drugs as Pharmacokinetic Modifiers of Soft Nanomaterials. Mol. Pharmaceutics, 2022, 19(11), 4080–4097. doi: 10.1021/acs.molpharmaceut.2c00528
  219. Ong, S. C.; Belgi, A.; Merriman, A. L.; Delaine, C. A.; van Lierop, B.; Andrikopoulos, S.; Robinson, A. J.; Forbes, B. E. Minimizing Mitogenic Potency of Insulin Analogues Through Modification of a Disulfide Bond. Front Endocrinol (Lausanne), 2022, 13, 907864. doi: 10.3389/fendo.2022.907864
  220. Hoque, J.; Zeng, Y.; Newman, H.; Gonzales, G.; Lee, C.; Varghese, S. Microgel-Assisted Delivery of Adenosine to Accelerate Fracture Healing. ACS Biomater. Sci. Eng., 2022, 8(11), 4863–4872. doi: 10.1021/acsbiomaterials.2c00977
  221. Chung, Y. H.; Volckaert, B. A.; Steinmetz, N. F. Metastatic Colon Cancer Treatment Using S100A9-Targeted Cowpea Mosaic Virus Nanoparticles. Biomacromolecules, 2022, 23(12), 5127–5136. doi: 10.1021/acs.biomac.2c00873
  222. Liu, N.; Yang, C.; Liang, X.; Cao, K.; Xie, J.; Luo, Q.; Luo, H. Mesoporous Silica Nanoparticle-Encapsulated Bifidobacterium Attenuates Brain Aβ Burden and Improves Olfactory Dysfunction of APP/PS1 Mice by Nasal Delivery. Journal of Nanobiotechnology, 2022, 20(1), 439. doi: 10.1186/s12951-022-01642-z
  223. Brodszkij, E.; Westensee, I. N.; Holleufer, S. F.; Ade, C.; Andres, P. D. D.; Pedersen, J. S.; Städler, B. Membrane Composition of Polymer-Lipid Hybrid Vesicles. Applied Materials Today, 2022, 29, 101549. doi: 10.1016/j.apmt.2022.101549
  224. Backes, I. M.; Byrd, B. K.; Slein, M. D.; Patel, C. D.; Taylor, S. A.; Garland, C. R.; MacDonald, S. W.; Balazs, A. B.; Davis, S. C.; Ackerman, M. E.; Leib, D. A. Maternally Transferred MAbs Protect Neonatal Mice from HSV-Induced Mortality and Morbidity. Journal of Experimental Medicine, 2022, 219(12), e20220110. doi: 10.1084/jem.20220110
  225. Boehnke, N.; Straehla, J. P.; Safford, H. C.; Kocak, M.; Rees, M. G.; Ronan, M.; Rosenberg, D.; Adelmann, C. H.; Chivukula, R. R.; Nabar, N.; Berger, A. G.; Lamson, N. G.; Cheah, J. H.; Li, H.; Roth, J. A.; Koehler, A. N.; Hammond, P. T. Massively Parallel Pooled Screening Reveals Genomic Determinants of Nanoparticle Delivery. Science, 2022, 377(6604), eabm5551. doi: 10.1126/science.abm5551
  226. Bulgakova, A.; Chubarov, A.; Dmitrienko, E. Magnetic Nylon 6 Nanocomposites for the Microextraction of Nucleic Acids from Biological Samples. Magnetochemistry, 2022, 8(8), 85. doi: 10.3390/magnetochemistry8080085
  227. Sapach, A. Yu.; Sindeeva, O. A.; Nesterchuk, M. V.; Tsitrina, A. A.; Mayorova, O. A.; Prikhozhdenko, E. S.; Verkhovskii, R. A.; Mikaelyan, A. S.; Kotelevtsev, Y. V.; Sukhorukov, G. B. Macrophage In Vitro and In Vivo Tracking via Anchored Microcapsules. ACS Appl. Mater. Interfaces, 2022, 14(46), 51579–51592. doi: 10.1021/acsami.2c12004
  228. Toporkova, Y. Y.; Smirnova, E. O.; Mukhtarova, L. S.; Grechkin, A. N. Lipoxygenase Pathway in Brown Algae: The Biosynthesis of Novel Oxylipins ‘Ectocarpins’ by Hydroperoxide Bicyclase CYP5164A3 of Ectocarpus Siliculosus. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2022, 1867(10), 159205. doi: 10.1016/j.bbalip.2022.159205
  229. Chatterjee, S.; Maltseva, D.; Kan, Y.; Hosseini, E.; Gonella, G.; Bonn, M.; Parekh, S. H. Lipid-Driven Condensation and Interfacial Ordering of FUS. Science Advances, 2022, 8(31), eabm7528. doi: 10.1126/sciadv.abm7528
  230. Khan, S. H.; Braet, S. M.; Koehler, S. J.; Elacqua, E.; Anand, G. S.; Okafor, C. D. Ligand-Induced Shifts in Conformational Ensembles That Describe Transcriptional Activation. eLife, 2022, 11, e80140. doi: 0.7554/eLife.80140
  231. Levina, A.; Repkova, M.; Kupryushkin, M.; Seryapina, A.; Shevelev, O.; Pyshnyi, D.; Zarytova, V.; Markel, A. In Vivo Hypotensive Effect of Aminosilanol-Based Nanocomposites Bearing Antisense Oligonucleotides. Journal of Drug Delivery Science and Technology, 2022, 75, 103612. doi: 10.1016/j.jddst.2022.103612
  232. Affonso de Oliveira, J. F.; Chan, S. K.; Omole, A. O.; Agrawal, V.; Steinmetz, N. F. In Vivo Fate of Cowpea Mosaic Virus In Situ Vaccine: Biodistribution and Clearance. ACS Nano, 2022, 16(11), 18315–18328. doi: 10.1021/acsnano.2c06143
  233. Khrenova, M.; Nikiforova, L.; Grabovenko, F.; Orlova, N.; Sinegubova, M.; Kolesov, D.; Zavyalova, E.; Spiridonova, V.; Zatsepin, T.; Zvereva, M. In Vitro Selection of an Aptamer Targeting SARS-CoV-2 Spike Protein with Nanopore Sequence Identification Reveals Discrimination Between the Authentic Strain and Omicron. ChemRxiv, 2022, preprint. doi: 10.26434/chemrxiv-2022-d9gcs
  234. Serda, M.; Malarz, K.; Korzuch, J.; Szubka, M.; Zubko, M.; Musioł, R. In Situ Cellular Localization of Nonfluorescent [60]Fullerene Nanomaterial in MCF-7 Breast Cancer Cells. ACS Biomater. Sci. Eng., 2022, 8(8), 3450–3462. doi: 10.1021/acsbiomaterials.2c00542
  235. Zhang, Y.; Xu, K.; Zhi, D.; Qian, M.; Liu, K.; Shuai, Q.; Qin, Z.; Xie, J.; Wang, K.; Yang, J. Improving Vascular Regeneration Performance of Electrospun Poly(ε-Caprolactone) Vascular Grafts via Synergistic Functionalization with VE-Cadherin/VEGF. Adv. Fiber Mater., 2022, 4(6), 1685–1702. doi: 10.1007/s42765-022-00213-z
  236. Kanamaru, T.; Sakurai, K.; Fujii, S. Impact of Polyethylene Glycol (PEG) Conformations on the In Vivo Fate and Drug Release Behavior of PEGylated Core-Cross-Linked Polymeric Nanoparticles. Biomacromolecules, 2022, 23(9), 3909–3918. doi: 10.1021/acs.biomac.2c00730
  237. Lu, Y.; Huntoon, K.; Lee, D.; Wang, Y.; Ha, J.; Qie, Y.; Li, X.; Schrank, B. R.; Dong, S.; Gallup, T. D.; Kang, M.; Zhao, H.; An, Y.; Yang, Z.; Li, J.; Kim, B. Y. S.; Jiang, W. Immunological Conversion of Solid Tumours Using a Bispecific Nanobioconjugate for Cancer Immunotherapy. Nat. Nanotechnol., 2022, 17(12), 1332–1341. doi: 10.1038/s41565-022-01245-7
  238. Bonova, P.; Koncekova, J.; Nemethova, M.; Petrova, K.; Bona, M.; Gottlieb, M. Identification of Proteins Responsible for the Neuroprotective Effect of the Secretome Derived from Blood Cells of Remote Ischaemic Conditioned Rats. Biomolecules, 2022, 12(10), 1423. doi: 10.3390/biom12101423
  239. Samuelian, J. S.; Baum, D. A. Identification of DNA Aptamers for Benzodiazepine Detection in Synthetic Urine. Analysis & Sensing, 2022, 2(6), e202200044. doi: 10.1002/anse.202200044
  240. Xu, J.; Chen, P.; Yu, C.; Shi, Q.; Wei, S.; Li, Y.; Qi, H.; Cao, Q.; Guo, C.; Wu, X.; Di, G. Hypoxic Bone Marrow Mesenchymal Stromal Cells-Derived Exosomal MiR-182-5p Promotes Liver Regeneration via FOXO1-Mediated Macrophage Polarization. The FASEB Journal, 2022, 36(10), e22553. doi: 10.1096/fj.202101868RRR
  241. Mahmoud, A. M.; Nowell, C. J.; Feeney, O.; van ’t Hag, L.; Davis, T. P.; Kempe, K. Hydrophobicity Regulates the Cellular Interaction of Cyanine5-Labeled Poly(3-Hydroxypropionate)-Based Comb Polymers. Biomacromolecules, 2022, 23(9), 3560–3571. doi: 10.1021/acs.biomac.2c00303
  242. Shvindelman, O.; Nordling-David, M. M.; Grad, E.; Golomb, G. Harnessing Monocytes for a Liposomal Rosiglitazone-Mediated Anti-Inflammatory Effect. Precision Nanomedicine, 2022, 5(4), 930–945. doi: 10.33218/001c.38312
  243. Phan, H.; Cavanagh, R.; Destouches, D.; Vacherot, F.; Brissault, B.; Taresco, V.; Penelle, J.; Couturaud, B. H2O2-Responsive Nanocarriers Prepared by RAFT-Mediated Polymerization-Induced Self-Assembly of N-(2-(Methylthio)Ethyl)Acrylamide for Biomedical Applications. ACS Appl. Polym. Mater., 2022, 4(10), 7778–7789. doi: 10.1021/acsapm.2c01327
  244. Quarta, C.; Stemmer, K.; Novikoff, A.; Yang, B.; Klingelhuber, F.; Harger, A.; Bakhti, M.; Bastidas-Ponce, A.; Baugé, E.; Campbell, J. E.; Capozzi, M.; Clemmensen, C.; Collden, G.; Cota, P.; Douros, J.; Drucker, D. J.; DuBois, B.; Feuchtinger, A.; Garcia-Caceres, C.; Grandl, G.; Hennuyer, N.; Herzig, S.; Hofmann, S. M.; Knerr, P. J.; Kulaj, K.; Lalloyer, F.; Lickert, H.; Liskiewicz, A.; Liskiewicz, D.; Maity, G.; Perez-Tilve, D.; Prakash, S.; Sanchez-Garrido, M. A.; Zhang, Q.; Staels, B.; Krahmer, N.; DiMarchi, R. D.; Tschöp, M. H.; Finan, B.; Müller, T. D. GLP-1-Mediated Delivery of Tesaglitazar Improves Obesity and Glucose Metabolism in Male Mice. Nat Metab, 2022, 4(8), 1071–1083. doi: 10.1038/s42255-022-00617-6
  245. Duskey, J. T.; Rinaldi, A.; Ottonelli, I.; Caraffi, R.; De Benedictis, C. A.; Sauer, A. K.; Tosi, G.; Vandelli, M. A.; Ruozi, B.; Grabrucker, A. M. Glioblastoma Multiforme Selective Nanomedicines for Improved Anti-Cancer Treatments. Pharmaceutics, 2022, 14(7), 1450. doi: 10.3390/pharmaceutics14071450
  246. Zhang, F.; Li, Z.; Duan, Y.; Abbas, A.; Mundaca-Uribe, R.; Yin, L.; Luan, H.; Gao, W.; Fang, R. H.; Zhang, L.; Wang, J. Gastrointestinal Tract Drug Delivery Using Algae Motors Embedded in a Degradable Capsule. Science Robotics, 2022, 7(70), eabo4160. doi: 10.1126/scirobotics.abo4160
  247. Morozov, V. N.; Klimovich, M. A.; Kostyukov, A. A.; Belousov, A. V.; Kolyvanova, M. A.; Nekipelova, T. D.; Kuzmin, V. A. Förster Resonance Energy Transfer from Hoechst 33258 to SYBR Green I in Cholesteric Liquid-Crystalline DNA. Journal of Luminescence, 2022, 252, 119381. doi: 10.1016/j.jlumin.2022.119381
  248. Chetverikov, P. E.; Bertone, M. A. First Rhyncaphytoptine Mite (Eriophyoidea, Diptilomiopidae) Parasitizing American Hazelnut (Corylus Americana): Molecular Identification, Confocal Microscopy, and Phylogenetic Position. Exp Appl Acarol, 2022, 88(1), 75–95. doi: 10.1007/s10493-022-00740-9
  249. Mekhail, K.; Lee, M.; Sugiyama, M.; Astori, A.; St-Germain, J.; Latreille, E.; Khosraviani, N.; Wei, K.; Li, Z.; Rini, J.; Lee, W. L.; Antonescu, C.; Raught, B.; Fairn, G. D. FASN Inhibitor TVB-3166 Prevents S-Acylation of the Spike Protein of Human Coronaviruses. Journal of Lipid Research, 2022, 63(9), 100256. doi: 10.1016/j.jlr.2022.100256
  250. Britton, B. M.; London, J. A.; Martin-Lopez, J.; Jones, N. D.; Liu, J.; Lee, J.-B.; Fishel, R. Exploiting the Distinctive Properties of the Bacterial and Human MutS Homolog Sliding Clamps on Mismatched DNA. Journal of Biological Chemistry, 2022, 298(11), 102505. doi: 10.1016/j.jbc.2022.102505
  251. Garcia Maset, R.; Hapeshi, A.; Hall, S.; Dalgliesh, R. M.; Harrison, F.; Perrier, S. Evaluation of the Antimicrobial Activity in Host-Mimicking Media and In Vivo Toxicity of Antimicrobial Polymers as Functional Mimics of AMPs. ACS Appl. Mater. Interfaces, 2022, 14(29), 32855–32868. doi: 10.1021/acsami.2c05979
  252. Naeimipour, S.; Rasti Boroojeni, F.; Selegård, R.; Aili, D. Enzymatically Triggered Deprotection and Cross-Linking of Thiolated Alginate-Based Bioinks. Chem. Mater., 2022, 34(21), 9536–9545. doi: 10.1021/acs.chemmater.2c02037
  253. Lee, S. E.; Lee, C. M.; Won, J. E.; Jang, G.-Y.; Lee, J. H.; Park, S. H.; Kang, T. H.; Han, H. D.; Park, Y.-M. Enhancement of Anticancer Immunity by Immunomodulation of Apoptotic Tumor Cells Using Annexin A5 Protein-Labeled Nanocarrier System. Biomaterials, 2022, 288, 121677. doi: 10.1016/j.biomaterials.2022.121677
  254. Dragulska, S. A.; Poursharifi, M.; Chen, Y.; Wlodarczyk, M. T.; Acosta Santiago, M.; Dottino, P.; Martignetti, J. A.; Mieszawska, A. J. Engineering and Validation of a Peptide-Stabilized Poly(Lactic-Co-Glycolic) Acid Nanoparticle for Targeted Delivery of a Vascular Disruptive Agent in Cancer Therapy. Bioconjugate Chem., 2022, 33(12), 2348–2360. doi: 10.1021/acs.bioconjchem.2c00418
  255. Chernyshev, V. S.; Nozdriukhin, D.; Chuprov-Netochin, R.; Tsydenzhapova, E.; Novoselova, M.; Gorin, D.; Yashchenok, A. Engineered Multicompartment Vesicosomes for Selective Uptake by Living Cells. Colloids and Surfaces B: Biointerfaces, 2022, 220, 112953. doi: 10.1016/j.colsurfb.2022.112953
  256. Hao, D.; Lu, L.; Song, H.; Duan, Y.; Chen, J.; Carney, R.; Li, J. J.; Zhou, P.; Nolta, J.; Lam, K. S.; Leach, J. K.; Farmer, D. L.; Panitch, A.; Wang, A. Engineered Extracellular Vesicles with High Collagen-Binding Affinity Present Superior in Situ Retention and Therapeutic Efficacy in Tissue Repair. Theranostics, 2022, 12(13), 6021–6037. doi: 10.7150/thno.70448
  257. Manspeaker, M. P.; O’Melia, M. J.; Thomas, S. N. Elicitation of Stem-like CD8+ T Cell Responses via Lymph Node-Targeted Chemoimmunotherapy Evokes Systemic Tumor Control. J Immunother Cancer, 2022, 10(9), e005079. doi: 10.1136/jitc-2022-005079
  258. Santos-Coquillat, A.; Herreros-Pérez, D.; Samaniego, R.; González, M. I.; Cussó, L.; Desco, M.; Salinas, B. Dual-Labeled Nanoparticles Based on Small Extracellular Vesicles for Tumor Detection. Biol Direct, 2022, 17(1), 31. doi: 10.1186/s13062-022-00345-7
  259. Xu, S.; Zhang, P.; Heing-Becker, I.; Zhang, J.; Tang, P.; Bej, R.; Bhatia, S.; Zhong, Y.; Haag, R. Dual Tumor- and Subcellular-Targeted Photodynamic Therapy Using Glucose-Functionalized MoS2 Nanoflakes for Multidrug-Resistant Tumor Ablation. Biomaterials, 2022, 290, 121844. doi: 10.1016/j.biomaterials.2022.121844
  260. Wiemann, J. T.; Nguyen, D.; Li, Y.; Yu, Y. Domain-Selective Disruption and Compression of Phase-Separated Lipid Vesicles by Amphiphilic Janus Nanoparticles. iScience, 2022, 25(12), 105525. doi: 10.1016/j.isci.2022.105525
  261. Kang, K.; Shi, Q.; Wang, X.; Chen, Y.-G. Dishevelled Phase Separation Promotes Wnt Signalosome Assembly and Destruction Complex Disassembly. Journal of Cell Biology, 2022, 221(12), e202205069. doi: 10.1083/jcb.202205069
  262. McGuire, C. C.; Robert, J. R. Developmental Exposure to Thyroid Disrupting Chemical Mixtures Alters Metamorphosis and Post-Metamorphic Thymocyte Differentiation. Current Research in Toxicology, 2022, 3, 100094. doi: 10.1016/j.crtox.2022.100094
  263. Cheng, A. G.; Ho, P.-Y.; Aranda-Díaz, A.; Jain, S.; Yu, F. B.; Meng, X.; Wang, M.; Iakiviak, M.; Nagashima, K.; Zhao, A.; Murugkar, P.; Patil, A.; Atabakhsh, K.; Weakley, A.; Yan, J.; Brumbaugh, A. R.; Higginbottom, S.; Dimas, A.; Shiver, A. L.; Deutschbauer, A.; Neff, N.; Sonnenburg, J. L.; Huang, K. C.; Fischbach, M. A. Design, Construction, and in Vivo Augmentation of a Complex Gut Microbiome. Cell, 2022, 185(19), 3617-3636.e19. doi: 10.1016/j.cell.2022.08.003
  264. Carraro, C.; Bonaguro, L.; Schulte-Schrepping, J.; Horne, A.; Oestreich, M.; Warnat-Herresthal, S.; Helbing, T.; De Franco, M.; Haendler, K.; Mukherjee, S.; Ulas, T.; Gandin, V.; Goettlich, R.; Aschenbrenner, A. C.; Schultze, J. L.; Gatto, B. Decoding Mechanism of Action and Sensitivity to Drug Candidates from Integrated Transcriptome and Chromatin State. eLife, 2022, 11, e78012. doi: 10.7554/eLife.78012
  265. Nakamura, M.; Fujiwara, K.; Doi, N. Cytoplasmic Delivery of SiRNA Using Human-Derived Membrane Penetration-Enhancing Peptide. Journal of Nanobiotechnology, 2022, 20(1), 458. doi: 10.1186/s12951-022-01667-4
  266. Chen, Q.; Menon, R.; Calder, L. J.; Tolar, P.; Rosenthal, P. B. Cryomicroscopy Reveals the Structural Basis for a Flexible Hinge Motion in the Immunoglobulin M Pentamer. Nat Commun, 2022, 13(1), 6314. doi: 10.1038/s41467-022-34090-2
  267. Futamata, H.; Fukuda, M.; Umeda, R.; Yamashita, K.; Tomita, A.; Takahashi, S.; Shikakura, T.; Hayashi, S.; Kusakizako, T.; Nishizawa, T.; Homma, K.; Nureki, O. Cryo-EM Structures of Thermostabilized Prestin Provide Mechanistic Insights Underlying Outer Hair Cell Electromotility. Nat Commun, 2022, 13(1), 6208. doi: 10.1038/s41467-022-34017-x
  268. Pauwels, M. J.; Xie, J.; Ceroi, A.; Balusu, S.; Castelein, J.; Van Wonterghem, E.; Van Imschoot, G.; Ward, A.; Menheniott, T. R.; Gustafsson, O.; Combes, F.; EL Andaloussi, S.; Sanders, N. N.; Mäger, I.; Van Hoecke, L.; Vandenbroucke, R. E. Choroid Plexus-Derived Extracellular Vesicles Exhibit Brain Targeting Characteristics. Biomaterials, 2022, 290, 121830. doi: 10.1016/j.biomaterials.2022.121830
  269. Liu, B.; Zhuang, S.; Tian, R.; Liu, Y.; Wang, Y.; Lei, X.; Wang, C. Chemoproteomic Profiling Reveals the Mechanism of Bile Acid Tolerance in Bacteria. ACS Chem. Biol., 2022, 17(9), 2461–2470. doi: 10.1021/acschembio.2c00286
  270. Gantsova, E. A.; Gavrilenkova, A. A.; Serova, O. V.; Deyev, I. E. Changes in the Expression of the Gapdh Gene in the Organs of Insrr Knockout Mice. Dokl Biol Sci, 2022, 505(1), 113–118. doi: 10.1134/S0012496622040056
  271. Schaal, J. L.; Bhattacharyya, J.; Brownstein, J.; Strickland, K. C.; Kelly, G.; Saha, S.; Milligan, J.; Banskota, S.; Li, X.; Liu, W.; Kirsch, D. G.; Zalutsky, M. R.; Chilkoti, A. Brachytherapy via a Depot of Biopolymer-Bound 131I Synergizes with Nanoparticle Paclitaxel in Therapy-Resistant Pancreatic Tumours. Nat. Biomed. Eng., 2022, 6(10), 1148–1166. doi: 10.1038/s41551-022-00949-4
  272. Costabile, G.; Mitidieri, E.; Visaggio, D.; Provenzano, R.; Miro, A.; Quaglia, F.; d’Angelo, I.; Frangipani, E.; Sorrentino, R.; Visca, P.; d’Emmanuele di Villa Bianca, R.; Ungaro, F. Boosting Lung Accumulation of Gallium with Inhalable Nano-Embedded Microparticles for the Treatment of Bacterial Pneumonia. International Journal of Pharmaceutics, 2022, 629, 122400. doi: 10.1016/j.ijpharm.2022.122400
  273. Zeng, Y.; Shen, Y.; Wu, S.; Cai, L.; Wang, Z.; Cai, K.; Shen, J.; Hii Ru Yie, K.; Zhang, H.; Xu, L.; Liu, J. Bone-Targeting PLGA Derived Lipid Drug Delivery System Ameliorates Bone Loss in Osteoporotic Ovariectomized Rats. Materials & Design, 2022, 221, 110967. doi: 10.1016/j.matdes.2022.110967
  274. Grossenbacher, P.; C. Essers, M.; Moser, J.; A. Singer, S.; Häusler, S.; Stieger, B.; Rougier, J.-S.; Lochner, M. Bioorthogonal Site-Selective Conjugation of Fluorescent Dyes to Antibodies: Method and Potential Applications. RSC Advances, 2022, 12(44), 28306–28317. doi: 10.1039/D2RA05580E
  275. Egorova, D. A.; Solovyev, A. I.; Polyakov, N. B.; Danilova, K. V.; Scherbakova, A. A.; Kravtsov, I. N.; Dmitrieva, M. A.; Rykova, V. S.; Tutykhina, I. L.; Romanova, Y. M.; Gintsburg, A. L. Biofilm Matrix Proteome of Clinical Strain of P. Aeruginosa Isolated from Bronchoalveolar Lavage of Patient in Intensive Care Unit. Microbial Pathogenesis, 2022, 170, 105714. doi: 10.1016/j.micpath.2022.105714
  276. Bodin, J.-B.; Gateau, J.; Coïs, J.; Lucas, T.; Lefebvre, F.; Moine, L.; Noiray, M.; Cailleau, C.; Denis, S.; Clavier, G.; Tsapis, N.; Méallet-Renault, R. Biocompatible and Photostable Photoacoustic Contrast Agents as Nanoparticles Based on Bodipy Scaffold and Polylactide Polymers: Synthesis, Formulation, and In Vivo Evaluation. ACS Appl. Mater. Interfaces, 2022, 14(36), 40501–40512. doi: 10.1021/acsami.2c04874
  277. Grzelak, J.; Teles, M.; Roher, N.; Grayston, A.; Rosell, A.; Gich, M.; Roig, A. Bioevaluation of Magnetic Mesoporous Silica Rods: Cytotoxicity, Cell Uptake and Biodistribution in Zebrafish and Rodents. RSC Advances, 2022, 12(49), 31878–31888. doi: 10.1039/D2RA05750F
  278. Abakumova, T. O.; Gusliakova, O. I.; Cvjetinovic, J.; Efimova, O. I.; Konovalova, E. V.; Schulga, A. A.; Zatsepin, T. S.; Gorin, D. A.; Yashchenok, A. M.; Deyev, S. M. Barnase-Loaded Vaterite Nanoparticles Functionalized by EpCAM Targeting Vectors for the Treatment of Lung Diseases. ACS Appl. Nano Mater., 2022, 5(8), 10744–10754. doi: 10.1021/acsanm.2c02078
  279. Baharlou, H.; Canete, N.; Vine, E. E.; Hu, K.; Yuan, D.; Sandgren, K. J.; Bertram, K. M.; Nasr, N.; Rhodes, J. W.; Gosselink, M. P.; Di Re, A.; Reza, F.; Ctercteko, G.; Pathma-Nathan, N.; Collins, G.; Toh, J.; Patrick, E.; Haniffa, M. A.; Estes, J. D.; Byrne, S. N.; Cunningham, A. L.; Harman, A. N. An in Situ Analysis Pipeline for Initial Host-Pathogen Interactions Reveals Signatures of Human Colorectal HIV Transmission. Cell Reports, 2022, 40(12), 111385. doi: 10.1016/j.celrep.2022.111385
  280. Hu, C.; Ni, D.; Nam, K. H.; Majumdar, S.; McLean, J.; Stahlberg, H.; Terns, M. P.; Ke, A. Allosteric Control of Type I-A CRISPR-Cas3 Complexes and Establishment as Effective Nucleic Acid Detection and Human Genome Editing Tools. Molecular Cell, 2022, 82(15), 2754-2768.e5. doi: 10.1016/j.molcel.2022.06.007
  281. Abucayon, E. G.; Whalen, C.; Torres, O. B.; Duval, A. J.; Sulima, A.; Antoline, J. F. G.; Oertel, T.; Barrientos, R. C.; Jacobson, A. E.; Rice, K. C.; Matyas, G. R. A Rapid Method for Direct Quantification of Antibody Binding-Site Concentration in Serum. ACS Omega, 2022, 7(30), 26812–26823. doi: 10.1021/acsomega.2c03237
  282. Kolyvanova, M. A.; Klimovich, M. A.; Belousov, A. V.; Kuzmin, V. A.; Morozov, V. N. A Principal Approach to the Detection of Radiation-Induced DNA Damage by Circular Dichroism Spectroscopy and Its Dosimetric Application. Photonics, 2022, 9(11), 787. doi: 10.3390/photonics9110787
  283. Chen, H. H.; Khatun, Z.; Wei, L.; Mekkaoui, C.; Patel, D.; Kim, S. J. W.; Boukhalfa, A.; Enoma, E.; Meng, L.; Chen, Y. I.; Kaikkonen, L.; Li, G.; Capen, D. E.; Sahu, P.; Kumar, A. T. N.; Blanton, R. M.; Yuan, H.; Das, S.; Josephson, L.; Sosnovik, D. E. A Nanoparticle Probe for the Imaging of Autophagic Flux in Live Mice via Magnetic Resonance and Near-Infrared Fluorescence. Nat. Biomed. Eng, 2022, 6(9), 1045–1056. doi: 10.1038/s41551-022-00904-3
  284. He, J.-X.; Fei, Z.-C.; Fu, L.; Tian, C.-P.; He, F.-C.; Chi, H.; Yang, J. A Modification-Centric Assessment Tool for the Performance of Chemoproteomic Probes. Nat Chem Biol, 2022, 18(8), 904–912. doi: 10.1038/s41589-022-01074-8
  285. Miyazaki, T.; Chen, S.; Florinas, S.; Igarashi, K.; Matsumoto, Y.; Yamasoba, T.; Xu, Z.-Q.; Wu, H.; Gao, C.; Kataoka, K.; Christie, R. J.; Cabral, H. A Hoechst Reporter Enables Visualization of Drug Engagement In Vitro and In Vivo: Toward Safe and Effective Nanodrug Delivery. ACS Nano, 2022, 16(8), 12290–12304. doi: 10.1021/acsnano.2c03170
  286. Zhang, S.; Feng, Y.; Meng, M.; Li, Z.; Li, H.; Lin, L.; Xu, C.; Chen, J.; Hao, K.; Tang, Z.; Tian, H.; Chen, X. A Generally Minimalist Strategy of Constructing Biomineralized High-Efficiency Personalized Nanovaccine Combined with Immune Checkpoint Blockade for Cancer Immunotherapy. Biomaterials, 2022, 289, 121794. doi: 10.1016/j.biomaterials.2022.121794
  287. Kong, X.; Yan, K.; Deng, P.; Fu, H.; Sun, H.; Huang, W.; Jiang, S.; Dai, J.; Zhang, Q. C.; Liu, J. G.; Xi, Q. LncRNA-Smad7 Mediates Cross-Talk between Nodal/TGF-β and BMP Signaling to Regulate Cell Fate Determination of Pluripotent and Multipotent Cells. Nucleic Acids Research, 2022, 50(18), 10526–10543. doi: 10.1093/nar/gkac780
  288. Tran, T. T.; Vaage, E. B.; Mehta, A.; Chopra, A.; Tietze, L.; Kolderup, A.; Anthi, A.; König, M.; Nygaard, G.; Lind, A.; Müller, F.; Nissen-Meyer, L. S.; Magnus, P.; Trogstad, L.; Mjaaland, S.; Søraas, A.; Midtvedt, K.; Åsberg, A.; Barratt-Due, A.; Medhus, A. W.; Høivik, M. L.; Lundin, K.; Karlsen, R. F.; Dahle, R.; Danielsson, K.; Thomassen, K. S.; Kro, G. B.; Cox, R. J.; Zhou, F.; Langeland, N.; Aukrust, P.; Melum, E.; Åvitsland, T. L.; Wiencke, K.; Holter, J. C.; Munthe, L. A.; Grødeland, G.; Andersen, J.-T.; Vaage, J. T.; Lund-Johansen, F. Titers of Antibodies against Ancestral SARS-CoV-2 Correlate with Levels of Neutralizing Antibodies to Multiple Variants. npj Vaccines, 2022, 7(1), 174. doi: 10.1038/s41541-022-00586-7
  289. Ikonnikova, A.; Kazakov, R.; Rodina, T.; Dmitriev, A.; Melnikov, E.; Zasedatelev, A.; Nasedkina, T. The Influence of Structural Variants of the CES1 Gene on the Pharmacokinetics of Enalapril, Presumably Due to Linkage Disequilibrium with the Intronic Rs2244613. Genes, 2022, 13(12), 2225. doi: 10.3390/genes13122225
  290. Shanaa O.A.; Rumyantsev A.M.; Sambuk E.V.; Padkina M.V. The synthesis of Broccoli RNA fluorescent aptamer in  Saccharomyces cerevisiae  yeast cells. EcoGen, 2022, 20(4), 339–348. doi: 10.17816/ecogen111012
  291. Xiao, Y.; Pandey, K.; Nicolás-Boluda, A.; Onidas, D.; Nizard, P.; Carn, F.; Lucas, T.; Gateau, J.; Martin-Molina, A.; Quesada-Pérez, M.; del Mar Ramos-Tejada, M.; Gazeau, F.; Luo, Y.; Mangeney, C. Synergic Thermo- and PH-Sensitive Hybrid Microgels Loaded with Fluorescent Dyes and Ultrasmall Gold Nanoparticles for Photoacoustic Imaging and Photothermal Therapy. ACS Appl. Mater. Interfaces, 2022, 14(49), 54439–54457. doi: 10.1021/acsami.2c12796
  292. Afonin, D. A.; Geras’kina, O. V.; Loseva, T. V.; Kirpichnikov, M. P.; Studitsky, V. M.; Feofanov, A. V. Structure and Affinity of Complexes between the DNA-Binding Domain of Swi4 and DNA. Biophysics, 2022, 67(5), 700–707. doi: 10.1134/S0006350922050037
  293. Jo, M. H.; Li, J.; Jaumouillé, V.; Hao, Y.; Coppola, J.; Yan, J.; Waterman, C. M.; Springer, T. A.; Ha, T. Single-Molecule Characterization of Subtype-Specific Β1 Integrin Mechanics. Nature Communications, 2022, 13(1), 7471. doi: 10.1038/s41467-022-35173-w
  294. Jang, H.-J.; Yoon, Y. J.; Choi, J.; Lee, Y.-J.; Lee, S.; Cho, W.; Byun, W. G.; Park, S. B.; Han, D. C.; Kwon, B.-M. S-Benproperine, an Active Stereoisomer of Benproperine, Suppresses Cancer Migration and Tumor Metastasis by Targeting ARPC2. Pharmaceuticals, 2022, 15(12), 1462. doi: 10.3390/ph15121462
  295. Apostolos, A. J.; Chordia, M. D.; Kolli, S. H.; Dalesandro, B. E.; Rutkowski, M. R.; Pires, M. M. Real-Time Non-Invasive Fluorescence Imaging of Gut Commensal Bacteria to Detect Dynamic Changes in the Microbiome of Live Mice. Cell Chemical Biology, 2022, 29(12), 1721-1728.e5. doi: 10.1016/j.chembiol.2022.11.010
  296. Zhubanova, G.; Filchakova, O. RC-4BC Cells Express Nicotinic and Muscarinic Acetylcholine Receptors. PLOS ONE, 2022, 17(12), e0279284. doi: 10.1371/journal.pone.0279284
  297. Kostyunin, A.; Glushkova, T.; Lobov, A.; Ovcharenko, E.; Zainullina, B.; Bogdanov, L.; Shishkova, D.; Markova, V.; Asanov, M.; Mukhamadiyarov, R.; Velikanova, E.; Akentyeva, T.; Rezvova, M.; Stasev, A.; Evtushenko, A.; Barbarash, L.; Kutikhin, A. Proteolytic Degradation Is a Major Contributor to Bioprosthetic Heart Valve Failure. Journal of the American Heart Association, 2022, 12, e028215. doi: 10.1161/JAHA.122.028215
  298. Nevers, Q.; Scrima, N.; Glon, D.; Bars, R. L.; Decombe, A.; Garnier, N.; Ouldali, M.; Lagaudrière-Gesbert, C.; Blondel, D.; Albertini, A.; Gaudin, Y. Properties of Rabies Virus Phosphoprotein and Nucleoprotein Biocondensates Formed in Vitro and in Cellulo. PLOS Pathogens, 2022, 18(12), e1011022. doi: 10.1371/journal.ppat.1011022
  299. Park, Y.; Moses, A. S.; Demessie, A. A.; Singh, P.; Lee, H.; Korzun, T.; Taratula, O. R.; Alani, A. W. G.; Taratula, O. Poly(Aspartic Acid)-Based Polymeric Nanoparticle for Local and Systemic MRNA Delivery. Mol. Pharmaceutics, 2022, 19(12), 4696–4704. doi: 10.1021/acs.molpharmaceut.2c00738
  300. Yim, J.; Lee, J.; Yi, S.; Koo, J. Y.; Oh, S.; Park, H.; Kim, S. S.; Bae, M. A.; Park, J.; Park, S. B. Phenotype-Based Screening Rediscovered Benzopyran-Embedded Microtubule Inhibitors as Anti-Neuroinflammatory Agents by Modulating the Tubulin–P65 Interaction. Exp Mol Med, 2022, 54(12), 2200–2209. doi: 10.1038/s12276-022-00903-z
  301. Khvorova, I.; Kostina, D.; Zainullina, B.; Fefilova, E.; Gromova, E.; Tikhilov, R.; Bozhkova, S.; Sereda, A.; Karelkin, V.; Malashicheva, A.; Lobov, A. Osteogenic Differentiation In Vitro of Human Osteoblasts Is Associated with Only Slight Shift in Their Proteomics Profile. Cell and Tissue Biology, 2022, 16, 540–546. doi: 10.1134/S1990519X22060025
  302. Kitaura, Y.; Nakamura, U.; Awada, C.; Yamaguchi, M.; Kim, M.; Ikeda, Y.; Matsuo, Y.; Moriishi, T.; Sawase, T.; Chung, U.; Hojo, H.; Ohba, S. Orally Administrable Peptides Derived from Egg Yolk Promote Skeletal Repair and Ameliorate Degenerative Skeletal Disorders in Mouse Models. Regenerative Therapy, 2022, 21, 584–595. doi: 10.1016/j.reth.2022.11.002
  303. Ang, S.-T. J.; Crombie, E. M.; Dong, H.; Tan, K.-T.; Hernando, A.; Yu, D.; Adamson, S.; Kim, S.; Withers, D. J.; Huang, H.; Tsai, S.-Y. Muscle 4EBP1 Activation Modifies the Structure and Function of the Neuromuscular Junction in Mice. Nat Commun, 2022, 13(1), 7792. doi: 10.1038/s41467-022-35547-0
  304. Raducanu, V.-S.; Tehseen, M.; Al-Amodi, A.; Joudeh, L. I.; De Biasio, A.; Hamdan, S. M. Mechanistic Investigation of Human Maturation of Okazaki Fragments Reveals Slow Kinetics. Nature Communications, 2022, 13(1), 6973. doi: 10.1038/s41467-022-34751-2
  305. Zhang, F.; Li, Z.; Duan, Y.; Luan, H.; Yin, L.; Guo, Z.; Chen, C.; Xu, M.; Gao, W.; Fang, R. H.; Zhang, L.; Wang, J. Extremophile-Based Biohybrid Micromotors for Biomedical Operations in Harsh Acidic Environments. Science Advances, 2022, 8(51), eade6455. doi: 10.1126/sciadv.ade6455
  306. Schürz, M.; Danmayr, J.; Jaritsch, M.; Klinglmayr, E.; Benirschke, H. M.; Matea, C.-T.; Zimmerebner, P.; Rauter, J.; Wolf, M.; Gomes, F. G.; Kratochvil, Z.; Heger, Z.; Miller, A.; Heuser, T.; Stanojlovic, V.; Kiefer, J.; Plank, T.; Johnson, L.; Himly, M.; Blöchl, C.; Huber, C. G.; Hintersteiner, M.; Meisner-Kober, N. EVAnalyzer: High Content Imaging for Rigorous Characterisation of Single Extracellular Vesicles Using Standard Laboratory Equipment and a New Open-Source ImageJ/Fiji Plugin. Journal of Extracellular Vesicles, 2022, 11(12), 12282. doi: 10.1002/jev2.12282
  307. Nishiguchi, A.; Taguchi, T. Engineering Thixotropic Supramolecular Gelatin-Based Hydrogel as an Injectable Scaffold for Cell Transplantation. Biomed. Mater., 2022, 18(1), 015012. doi: 10.1088/1748-605X/aca501
  308. Kim, R. M.; Huh, J.-H.; Yoo, S.; Kim, T. G.; Kim, C.; Kim, H.; Han, J. H.; Cho, N. H.; Lim, Y.-C.; Im, S. W.; Im, E.; Jeong, J. R.; Lee, M. H.; Yoon, T.-Y.; Lee, H.-Y.; Park, Q.-H.; Lee, S.; Nam, K. T. Enantioselective Sensing by Collective Circular Dichroism. Nature, 2022, 612(7940), 470–476. doi: 10.1038/s41586-022-05353-1
  309. Shin, J. S.; Li, S. DNA-Immobilized Fluorescent Polystyrene Nanoparticles as Probes with Tunable Detection Limits. ACS Omega, 2022, 7(51), 48310–48319. doi: 10.1021/acsomega.2c06498
  310. Zhang, D.-X.; Tieu, T.; Esser, L.; Wojnilowicz, M.; Lee, C.-H.; Cifuentes-Rius, A.; Thissen, H.; Voelcker, N. H. Differential Surface Engineering Generates Core–Shell Porous Silicon Nanoparticles for Controlled and Targeted Delivery of an Anticancer Drug. ACS Appl. Mater. Interfaces, 2022, 14(49), 54539–54549. doi: 10.1021/acsami.2c16370
  311. Rabanel, J.-M.; Mirbagheri, M.; Olszewski, M.; Xie, G.; Le Goas, M.; Latreille, P.-L.; Counil, H.; Hervé, V.; Silva, R. O.; Zaouter, C.; Adibnia, V.; Acevedo, M.; Servant, M. J.; Martinez, V. A.; Patten, S. A.; Matyjaszewski, K.; Ramassamy, C.; Banquy, X. Deep Tissue Penetration of Bottle-Brush Polymers via Cell Capture Evasion and Fast Diffusion. ACS Nano, 2022, 16(12), 21583–21599. doi: 10.1021/acsnano.2c10554
  312. Hao, J.; Jin, R.; Zeng, J.; Hua, Y.; Yorek, M. S.; Liu, L.; Mandal, A.; Li, J.; Zheng, H.; Sun, Y.; Yi, Y.; Yin, D.; Zheng, Q.; Li, X.; Ng, C. K.; Rouchka, E. C.; Egilmez, N. K.; Jabbari, A.; Li, B. Consumption of Fish Oil High-Fat Diet Induces Murine Hair Loss via Epidermal Fatty Acid Binding Protein in Skin Macrophages. Cell Reports, 2022, 41(11), 111804. doi: 10.1016/j.celrep.2022.111804
  313. Garanina, A. S.; Efremova, M. V.; Machulkin, A. E.; Lyubin, E. V.; Vorobyeva, N. S.; Zhironkina, O. A.; Strelkova, O. S.; Kireev, I. I.; Alieva, I. B.; Uzbekov, R. E.; Agafonov, V. N.; Shchetinin, I. V.; Fedyanin, A. A.; Erofeev, A. S.; Gorelkin, P. V.; Korchev, Y. E.; Savchenko, A. G.; Abakumov, M. A. Bifunctional Magnetite–Gold Nanoparticles for Magneto-Mechanical Actuation and Cancer Cell Destruction. Magnetochemistry, 2022, 8(12), 185. doi: 10.3390/magnetochemistry8120185
  314. Budiardjo, S. J.; Stevens, J.J.; Calkins, A. L.; Ikujuni, A. P.; Wimalasena, V. K.; Firlar, E.; Case, D. A.; Biteen, J. S.; Kaelber, J. T.; Slusky, J. S.G. Colicin E1 Opens Its Hinge to Plug TolC. eLife, 2022, 11, e73297. doi: 10.7554/eLife.73297
  315. Singh, A.; Jothiprakasam, T.; Raghavan, J.V.; Jhunjhunwala, S. Sterile Inflammation Alters Neutrophil Kinetics in Mice. Journal of Leukocyte Biology, 2022, 112(3), 395-409. doi: 10.1002/JLB.1A0321-132RR
  316. Lee, M.S.; Hyun, H.; Park, I.; Kim, S.; Jang, D.-H.; Kim, S.; Im, J.-K.; Kim, H.; Lee, J.H.; Kwon, T.; Kang, J.H. Quantitative fluorescence in situ hybridization (FISH) of magnetically confined bacteria enables rapid determination of early-stage human bacteremia. Small Methods, 2022, 6(3), e2101239. doi: 10.1002/smtd.202101239
  317. Ast, J.; Novak, A.N.; Podewin, T.; Fine, N.H.F.; Jones, B.; Tomas, A.; Birke, R.; Roßmann, K.; Mathes, B:; Eichhorst, J.; Lehmann, M.; Linnemann, A.K.; Hodson, D.J.; Broichhagen, J. Expanded LUXendin color palette for GLP1R detection and visualization in vitro and in vivo. JACS Au, 2022, 2(4), 1007-1017. doi: 10.1021/jacsau.2c00130
  318. Futamata, H.; Fukuda, M.; Umeda, R.; Yamashita, K.; Takahashi, S.; Shikakura, Ta.; Hayashi, S.; Homma, K.; Nishizawa, T.; Nureki, O. Cryo-EM structures of thermostabilized prestin provide mechanistic insights underlying outer hair cell electromotility. Nature Communications, 2022, 13, 6208. doi: 10.1038/s41467-022-34017-x
  319. Cooley, M.B.; Abenojar, E.C.; Wegierak, D.; Gupta, A.S.; Kolios, M.C.; Exner, A.A. Characterization of the Interaction of Nanobubble Ultrasound Contrast Agents with Human Blood Components. Bioactive Materials, 2022, 19, 642-652. doi: 10.1016/j.bioactmat.2022.05.001
  320. Yagolovich, A.V.; Isakova, A.A.; Artykov, A.A.; Vorontsova, Y.V.; Mazur, D.V.; Antipova, N.V.; Pavlyukov, M.S.; Shakhparonov, M.I.; Gileva, A.M.; Markvicheva, E.A.; Plotnikova, E.A.; Pankratov, A.A.; Kirpichnikov, M.P.; Gasparian, M.E.; Dolgikh, D.A. DR5-Selective TRAIL Variant DR5-B Functionalized with Tumor-Penetrating iRGD Peptide for Enhanced Antitumor Activity against Glioblastoma. International Journal of Molecular Sciences, 2022, 23(20), 12687. doi: 10.3390/ijms232012687
  321. Gruenke, P.R.; Aneja, R.; Welbourn, S.; Ukah, O.B.; Sarafianos, S.G.; Burke, D.H.; Lange, M.J. Selection and identification of an RNA aptamer that specifically binds the HIV-1 capsid lattice and inhibits viral replication. Nucleic Acids Research, 2022, 50(3), 1701–1717. doi: 10.1093/nar/gkab1293
  322. Bellat, V.; Michel, A.O.; Thomas, C.; Stokol, T.; Choi, B.; Law, B. A urinary drug-disposing approach as an alternative to intravesical chemotherapy for treating non-muscle invasive bladder cancer. Cancer Research, 2022, 82(7), 1409–1422. doi: 10.1158/0008-5472.CAN-21-2897
  323. Yin, X.; Ren, J.; Lan, W.; Chen, Y.; Ouyang, M.; Su, H.; Zhang, L.; Zhu, J.; Zhang, C. Microfluidics-assisted optimization of highly adhesive haemostatic hydrogel coating for arterial puncture. Bioactive Materials, 2022, 12, 133-142. doi: 10.1016/j.bioactmat.2021.10.009
  324. Delvaux, N.A.; Mathew, B.; Rice, K.G. Fluorescent Labeling of Plasmid DNA for Gene Delivery: Implications of Dye Hydrophobicity on Labeling Efficiencies and Nanoparticle Size. Analytical Biochemistry, 2022, 644, 113895. doi: 10.1016/j.ab.2020.113895
  325. Kolyvanova, M.A.; Klimovich, M.A.; Shibaeva, A.V.; Koshevaya, E.D.; Bushmanov, Y.A.; Belousov, A.V.; Kuzmin, V.A.; Morozov, V.N. Cholesteric liquid-crystalline DNA – a new type of chemical detector of ionizing radiation. Liquid Crystals, 2022, 49(10). doi: 10.1080/02678292.2022.2032854
  326. Sun, F.; Wang, Y.; Wang, Q.; Wang, X.; Yao, P.; Feng, W.; Yuan, Q.; Qi, X.; Chen, S.; Pu, W.; Huang, R.; Dai, Q.; lv, J.; Wang, Q.; Shen, W.; Xia, P.; Zhang, D. Self-Illuminating Triggered Release of Therapeutics from Photocleavable Nanoprodrug for the Targeted Treatment of Breast Cancer. ACS Applied Materials & Interfaces, 2022, 14(7), 8766–8781. doi: 10.1021/acsami.1c21665
  327. Sokolov, A. V., Isakova-Sivak, I. N., Mezhenskaya, D. A., Kostevich, V. A., Gorbunov, N. P., Elizarova, A. Y., Matyushenko, V. A.; Berson, Y. M.; Grudinina, N. A.; Kolmakov, N. N.; Zabrodskaya, Y. A.; Komlev, A. S.; Semak, I. V.; Budevich, A. I.; Rudenko, L. G.; Vasilyev, V. B. Molecular mimicry of the receptor-binding domain of the SARS-CoV-2 spike protein: from the interaction of spike-specific antibodies with transferrin and lactoferrin to the antiviral effects of human recombinant lactoferrin. BioMetals, 2022. doi: 10.1007/s10534-022-00458-6
  328. Sokolov, A.; Isakova-Sivak, I.; Grudinina, N.; Mezhenskaya, D.; Litasova, E.; Kostevich, V.; Stepanova, E.; Rak, A.; Sychev, I.; Kirik, O.; & Rudenko, L. Ferristatin II Efficiently Inhibits SARS-CoV-2 Replication in Vero Cells. Viruses, 2022, 14(2), 317. doi: 10.3390/v14020317
  329. Rueda-Alaña, E.; García-Moreno, F. Time in Neurogenesis: Conservation of the Developmental Formation of the Cerebellar Circuitry. Brain, Behavior and Evolution, 2022, 97, 33-47. doi: 10.1159/000519068
  330. Diaz-Salmeron, R.; Toussaint, B.; Cailleau, C.; Ponchel, G.; Bouchemal, K. Morphology-Dependent Bioadhesion and Bioelimination of Hyaluronan Particles Administered in the Bladder. Advanced NanoBiomed Research, 2022, 2(5), 2100138. doi: 10.1002/anbr.202100138
  331. Maltsev, D.I.; Mellanson, K.A.; Belousov, V.V.; Enikolopov, G.N.; Podgorny, O.V. The bioavailability time of commonly used thymidine analogues after intraperitoneal delivery in mice: labeling kinetics in vivo and clearance from blood serum. Histochemistry and Cell Biology, 2022, 157, 239–250. doi: 10.1007/s00418-021-02048-y
  332. Ivanova, A.; Gruzova, O.; Ermolaeva, E.; Astakhova, O.; Itaman, S.; Enikolopov, G.; Lazutkin, A. Synthetic Thymidine Analog Labeling without Misconceptions. Cells, 2022, 11(12), 1888. doi: 10.3390/cells11121888
  333. Han, Z.; Chen, C.; Xu, X.; Bai, R.; Staedtke, V.; Huang, J.; Chan, K.W.Y.; Xu, J.; Kamson, D.O.; Wen, Z.; Knutsson, L.; Zijl, P.C.M.; Liu, G. Dynamic contrast-enhanced CEST MRI using a low molecular weight dextran. NMR in Biomedicine, 2022, 35(3), e4649. doi: 10.1002/nbm.4649
  334. Lee, J.; Kang, Y.K.; Oh, E.; Jeong, J.; Im, S.H.; Kim, D.K.; Lee, H.; Kim, S.-G.; Jung, K.; Chung, H.J. Nano-assembly of a Chemically Tailored Cas9 Ribonucleoprotein for In Vivo Gene Editing and Cancer Immunotherapy. Chemistry of Materials, 2022, 34(2), 547–561. doi: 10.1021/acs.chemmater.1c02844
  335. Vakhrushev, A.V.; Demin, A.M.; Krasnov, V.P. Synthesis of fluorescent GRGD peptide derivatives. AIP Conference Proceedings, 2022, 2390(1), 020083. doi: 10.1063/5.0069274
  336. Li, F.; Wei, Y.; Zhao, J.; Zhang, L.; Li, Q. In vivo pharmacokinetic study of a Cucurbita moschata polysaccharide after oral administration. International Journal of Biological Macromolecules, 2022, 203, 19–28. doi: 10.1016/j.ijbiomac.2022.01.111
  337. Kang, Y.; Nack, L.M.; Liu, Yang and.; Qi, B.; Huang, Y.; Liu, Z.; Chakraborty, I.; Schulz, F.; Ahmed, A.A.A.; Poveda, M.C.; Hafizi, F.; Roy, S.; Mutas, M.; Holzapfel, M.; Sanchez-Cano, C.; Wegner, K.D.; Feliu, N.; Parak, W.J. Quantitative considerations about the size dependence of cellular entry and excretion of colloidal nanoparticles for different cell types. ChemTexts, 2022, 8(1), 9. doi: 10.1007/s40828-021-00159-6
  338. Chung, I.J.; Moon, H.; Jeon, S.I.; Lee, H.J.; Ahn, C.-H. Ultrasound-triggered imaging and drug delivery using microbubble-self-aggregate complexes. Journal of Biomaterials Science, Polymer Edition, 2022, 33(1), 57–76. doi: 10.1080/09205063.2021.1976362
  339. Mamot, A.; Sikorski, P.J.; Siekierska, A.; de Witte, P.; Kowalska, J.; Jemielity, J. Ethylenediamine derivatives efficiently react with oxidized RNA 3′ ends providing access to mono and dually labelled RNA probes for enzymatic assays and in vivo translation. Nucleic Acids Research, 2022, 50(1), e3. doi: 10.1093/nar/gkab867
  340. Jobbins, A.M.; Campagne, S.; Weinmeister, R.; Lucas, C.M.; Gosliga, A.R.; Clery, A.; Chen, L.; Eperon, L.P.; Hodson, M.J.; Hudson, A.J.; Allain, F.H.T.; Eperon, I.C. Exon-independent recruitment of SRSF1 is mediated by U1 snRNP stem-loop 3. The EMBO Journal, 2022, 41(1), e107640. doi: 10.15252/embj.2021107640
  341. Kumar, A.; Singam, A.; Swaminathan, G.; Killi, N.; Tangudu, N.K.; Jose, J.; Rathna G.V.N.; Kumar, L.D. Combinatorial therapy using RNAi and curcumin nano-architectures regresses tumors in breast and colon cancer models. Nanoscale, 2022, 14(2), 492–505. doi: 10.1039/D1NR04411G
  342. Mohale, M.; Gundampati, R.K.; Thallapuranam, S.; Heyes, C.D. Site-specific labeling and functional efficiencies of human fibroblast growth Factor-1 with a range of fluorescent dyes in the flexible N-Terminal region and a rigid β-turn region. Analytical Biochemistry, 2022, 640, 114524. doi: 10.1016/j.ab.2021.114524
  343. Iacobazzi, R.M.; Arduino, I.; Di Fonte, R.; Lopedota, A.A.; Serratì, S.; Racaniello, G.; Bruno, V.; Laquintana, V.; Lee, B.-C.; Silvestris, N.; Leonetti, F.; Denora, N.; Porcelli, L.; Azzariti, A. Microfluidic-Assisted Preparation of Targeted pH-Responsive Polymeric Micelles Improves Gemcitabine Effectiveness in PDAC: In Vitro Insights. Cancers, 2022, 14(1), 5. doi: 10.3390/cancers14010005
  344. Guo, H.; Liu, L.; Hu, Q.; Dou, H. Monodisperse ZIF-8@dextran nanoparticles co-loaded with hydrophilic and hydrophobic functional cargos for combined near-infrared fluorescence imaging and photothermal therapy. Acta Biomaterialia, 2022, 137, 290–304. doi: 10.1016/j.actbio.2021.10.006
  345. Nekrasov, N.; Jaric, S.; Kireev, D.; Emelianov, A.V.; Orlov, A.V.; Gadjanski, I.; Nikitin, P.I.; Akinwande, D.; Bobrinetskiy, I. Real-time detection of ochratoxin A in wine through insight of aptamer conformation in conjunction with graphene field-effect transistяor. Biosensors and Bioelectronics, 2022, 200, 113890. doi: 10.1016/j.bios.2021.113890
  346. Mochalova, E. N.; Kotov, I. A.; Lifanov, D. A.; Chakraborti, S.; Nikitin, M. P. Imaging Flow Cytometry Data Analysis Using Convolutional Neural Network for Quantitative Investigation of Phagocytosis. Biotechnology and Bioengineering, 2022, 119(2), 626–635. doi: 10.1002/bit.27986
  347. Wachholz, V.; Mustafa, A.-H. M.; Zeyn, Y.; Henninger, S. J.; Beyer, M.; Dzulko, M.; Piée-Staffa, A.; Brachetti, C.; Haehnel, P. S.; Sellmer, A.; Mahboobi, S.; Kindler, T.; Brenner, W.; Nikolova, T.; Krämer, O. H. Inhibitors of Class I HDACs and of FLT3 Combine Synergistically against Leukemia Cells with Mutant FLT3. Arch Toxicol, 2022, 96(1), 177–193. doi: 10.1007/s00204-021-03174-1
  348. Wang, Y.; Song, X.; Zhuang, L.; Lang, H.; Yu, L.; Yan, X.; He, Z. Kinetic Control of Phytic Acid/Lixisenatide/Fe (III) Ternary Nanoparticles Assembly Process for Sustained Peptide Release. International Journal of Pharmaceutics, 2022, 611, 121317. doi: 10.1016/j.ijpharm.2021.121317
  349. Tully, M.; Hauptstein, N.; Licha, K.; Meinel, L.; Lühmann, T.; Haag, R. Linear Polyglycerol for N-Terminal-Selective Modification of Interleukin-4. Journal of Pharmaceutical Sciences, 2022, 111(6), 1642–1651. doi: 10.1016/j.xphs.2021.10.032
  350. Lim, S.; An, S. B.; Jung, M.; Joshi, H. P.; Kumar, H.; Kim, C.; Song, S. Y.; Lee, J.-R.; Kang, M.; Han, I.; Kim, B.-S. Local Delivery of Senolytic Drug Inhibits Intervertebral Disc Degeneration and Restores Intervertebral Disc Structure. Advanced Healthcare Materials, 2022, 11(2), 2101483. doi: 10.1002/adhm.202101483
  351. Lim, S.; An, S. B.; Jung, M.; Joshi, H. P.; Kumar, H.; Kim, C.; Song, S. Y.; Lee, J.-R.; Kang, M.; Han, I.; Kim, B.-S. Local Delivery of Senolytic Drug Inhibits Intervertebral Disc Degeneration and Restores Intervertebral Disc Structure. Advanced Healthcare Materials, 2022, 11(2), 2101483. doi: 10.1002/adhm.202101483
  352. Geng, Y.; Xiang, J.; Shao, S.; Tang, J.; Shen, Y. Mitochondria-Targeted Polymer-Celastrol Conjugate with Enhanced Anticancer Efficacy. Journal of Controlled Release, 2022, 342, 122–133. doi: 10.1016/j.jconrel.2022.01.002
  353. Giudice, C. L.; Yang, J.; Poncin, M. A.; Adumeau, L.; Delguste, M.; Koehler, M.; Evers, K.; Dumitru, A. C.; Dawson, K. A.; Alsteens, D. Nanophysical Mapping of Inflammasome Activation by Nanoparticles via Specific Cell Surface Recognition Events. ACS Nano, 2022, 16(1), 306–316. doi: 10.1021/acsnano.1c06301
  354. An, S.; Nam, J.; Kanimozhi, C.; Song, Y.; Kim, S.; Shin, N.; Gopalan, P.; Kim, M. Photoimageable Organic Coating Bearing Cyclic Dithiocarbonate for a Multifunctional Surface. ACS Appl. Mater. Interfaces, 2022, 14(2), 3274–3283. doi: 10.1021/acsami.1c19559
  355. Zhou, H.; Chen, P.; Dai, F.; Wang, J. Up-Regulation of TGFBI and TGFB2 in the Plasma of Gestational Diabetes Mellitus Patients and Its Clinical Significance. Ir J Med Sci, 2022, 191(5), 2029–2033. doi: 10.1007/s11845-021-02838-2
  356. Nekrasov, N.; Jaric, S.; Kireev, D.; Emelianov, A. V.; Orlov, A. V.; Gadjanski, I.; Nikitin, P. I.; Akinwande, D.; Bobrinetskiy, I. Real-Time Detection of Ochratoxin A in Wine through Insight of Aptamer Conformation in Conjunction with Graphene Field-Effect Transistor. Biosensors and Bioelectronics, 2022, 200, 113890. doi: 10.1016/j.bios.2021.113890
  357. Muraru, S.; Muraru, S.; Nitu, F. R.; Ionita, M. Recent Efforts and Milestones for Simulating Nucleic Acid FRET Experiments through Computational Methods. J. Chem. Inf. Model., 2022, 62(1), 232–239. doi: 10.1021/acs.jcim.1c00957
  358. Jahn, K.; Kurz, B.; Sinke, C.; Kneer, J.; Riemer, O.; Ponseti, J.; Walter, M.; Beier, K. M.; Walter, H.; Frieling, H.; Schiffer, B.; Kruger, T. H. C. Serotonin System-Associated Genetic and Epigenetic Changes in Pedophilia and Child Sexual Offending. Journal of Psychiatric Research, 2022, 145, 60–69. doi: 10.1016/j.jpsychires.2021.11.042
  359. Francis, C.; Wroblewska, L.; Pegman, P.; Amiji, M. Systemic Biodistribution and Hepatocyte-Specific Gene Editing with CRISPR/Cas9 Using Hyaluronic Acid-Based Nanoparticles. Nanomedicine: Nanotechnology, Biology and Medicine, 2022, 40, 102488. doi: 10.1016/j.nano.2021.102488
  360. Wang, X.; Ansari, A.; Pierre, V.; Young, K.; Kothapalli, C.R.; von Recum, H.A.; Senyo, S.E. Injectable Extracellular Matrix Microparticles Promote Heart Regeneration in Mice with Post-ischemic Heart Injury. Advanced Healthcare Materials, 2022, 11(8), e2102265. doi: 10.1002/adhm.202102265
  361. Morris, M.A.; Jones, C.R.; Nowick, J.S. Synthesis and Application of Fluorescent Teixobactin Analogues. Methods in enzymology, 2022, 665, 233-258. doi: 10.1016/bs.mie.2021.12.006
  362. Hulce, K.R.; Jaishankar, P.; Lee, G.M.; Bohn, M.-F.; Connelly, E.J.; Wucherer, K.; Ongpipattanakul, C.; Volk, R.F.; Chuo, S.-W.; Arkin, M.R.; Renslo, A.R.; Craik, C.S. Inhibiting a dynamic viral protease by targeting a non-catalytic cysteine. Cell Chemical Biology, 2022, 29(5), 785-798.e19. doi: 10.1016/j.chembiol.2022.03.007
  363. Zhang, M.; Díaz-Celis, C.; Onoa, B.; Cañari-Chumpitaz, C.; Requejo, K.I.; Liu, J.; Vien, M.; Nogales, E.; Ren, G.; Bustamante, C. Molecular Organization of the Early Stages of Nucleosome Phase Separation Visualized by Cryo-Electron Tomography. Molecular Cell, 2022, 82(16), 3000-3014.e9. doi: 10.1016/j.molcel.2022.06.032
  364. Battaglini, M.; Feiner, N.; Tapeinos, C.; De Pasquale, D.; Pucci, C.; Marino, A.; Bartolucci, M.; Petretto, A.; Albertazzi, L.; Ciofani, G. Combining confocal microscopy, dSTORM, and mass spectroscopy to unveil the evolution of the protein corona associated with nanostructured lipid carriers during blood–brain barrier crossing†. Nanoscale, 2022, 14(36), 13292-13307. doi: 10.1039/d2nr00484d
  365. Kelley, C.P.; Haerle, M.C.; Wang, E.T. Negative autoregulation mitigates collateral RNase activity of repeat-targeting CRISPR-Cas13d in mammalian cells. Cell reports, 2022, 40(7), 111226. doi: 10.1016/j.celrep.2022.111226
  366. Bakaeva, Z.; Lizunova, N.; Tarzhanov, I.; Boyarkin, D.; Petrichuk, S.; Pinelis, V.; Fisenko, A.; Tuzikov, A.; Sharipov, R.; Surin, A. Lipopolysaccharide From E. coli Increases Glutamate-Induced Disturbances of Calcium Homeostasis, the Functional State of Mitochondria, and the Death of Cultured Cortical Neurons. Frontiers in Molecular Neuroscience, 2022, 14, 811171. doi: 10.3389/fnmol.2021.811171
  367. Zeng, H.; Xia, C.; Zhao, B.; Zhu, M.; Zhang, H.Y.; Zhang, D.; Rui, X.; Li, H.; Yuan, Y. Folic Acid–Functionalized Metal-Organic Framework Nanoparticles as Drug Carriers Improved Bufalin Antitumor Activity Against Breast Cancer. Frontiers in Pharmacology, 2022, 12, 747992. doi: 10.3389/fphar.2021.747992
  368. Stanton, J.-A.L.; O'Brien, R.; Hall, R.J.; Chernyavtseva, A.; Ha, H.J.; Jelley, L.; Mace, P.D.; Klenov, A.; Treece, J.M.; Fraser, J.D.; Clow, F.; Clarke, L.; Su, Y.; Kurup, H.M.; Filichev, V.V.; Rolleston, W.; Law, L.; Rendle, P.M.; Harris, L.D.; Wood, J.M.; Scully, T.W.; Ussher, J.E.; Grant, J.; Hore, T.A.; Moser, T.V.; Harfoot, R.; Lawley, B.; Quiñones-Mateu, M.E.; Collins, P.; Blaikie, R. Uncoupling Molecular Testing for SARS-CoV-2 From International Supply Chains. Frontiers in Public Health, 2022, 9, 808751. doi: 10.3389/fpubh.2021.808751
  369. Baranova, M.N.; Kudzhaev, A.M.; Mokrushina, Y.A.; Babenko, V.V.; Kornienko, M.A.; Malakhova, M.V.; Yudin, V.G.; Rubtsova, M.P.; Zalevsky, A.; Belozerova, O.A.; Kovalchuk, S.; Zhuravlev, Y.N.; Ilina, E.N.; Gabibov, A.G.; Smirnov, I.V.; Terekhov, S.S. Deep Functional Profiling of Wild Animal Microbiomes Reveals Probiotic Bacillus pumilus Strains with a Common Biosynthetic Fingerprint. International Journal of Molecular Sciences, 2022, 23(3), 1168. doi: 10.3390/ijms23031168
  370. Balatskiy, A.; Ozhimalov, I.; Balatskaya, M.; Savina, A.; Filatova, J.; Kalinina, N.; Popov, V.; Tkachuk, V. Immature Vascular Smooth Muscle Cells in Healthy Murine Arteries and Atherosclerotic Plaques: Localization and Activity. International Journal of Molecular Sciences, 2022, 23(3), 1744. doi: 10.3390/ijms23031744
  371. Bos, I.; Brink, E.; Michels, L.; Sprakel, J. DNA dynamics in complex coacervate droplets and micelles † † Electronic supplementary information (ESI) available. See DOI: 10.1039/d1sm01787j. Soft Matter, 2022, 18(10), 2012-2027. doi: 10.1039/d1sm01787j
  372. Okada, K.; Aoki, K.; Tabei, T.; Sugio, K.; Imai, K.; Bonkohara, Y.; Kamachi, Y. Key sequence features of CRISPR RNA for dual-guide CRISPR-Cas9 ribonucleoprotein complexes assembled with wild-type or HiFi Cas9. Nucleic Acids Research, 2022, 50(5), 2854-2871. doi: 10.1093/nar/gkac100
  373. Yabbarov, N.; Nikolskaya, E.; Sokol, M.; Mollaeva, M.; Chirkina, M.; Seregina, I.; Gulyaev, M.; Pirogov, Y.; Petrov, R. Synergetic Enhancement of Tumor Double-Targeted MRI Nano-Probe. International Journal of Molecular Sciences, 2022, 23(6), 3119. doi: 10.3390/ijms23063119
  374. Zavalin, K.; Hassan, A.; Fu, C.; Delpire, E.; Lagrange, A.H. Loss of KCC2 in GABAergic Neurons Causes Seizures and an Imbalance of Cortical Interneurons. Frontiers in Molecular Neuroscience, 2022, 15, 826427. doi: 10.3389/fnmol.2022.826427
  375. Hughes, K.R.; Saunders, M.N.; Landers, J.J.; Janczak, K.W.; Turkistani, H.; Rad, L.M.; Miller, S.D.; Podojil, J.R.; Shea, L.D.; O'Konek, J.J. Masked Delivery of Allergen in Nanoparticles Safely Attenuates Anaphylactic Response in Murine Models of Peanut Allergy. Frontiers in Allergy, 2022, 3, 829605. doi: 10.3389/falgy.2022.829605
  376. Wu, Y.; Zhong, Y.; Liao, X.; Miao, X.; Yu, J.; Lai, X.; Zhang, Y.; Ma, C.; Pan, H.; Wang, S. Transmembrane protein 108 inhibits the proliferation and myelination of oligodendrocyte lineage cells in the corpus callosum. Molecular Brain, 2022, 15, 33. doi: 10.1186/s13041-022-00918-7
  377. Blokhin, V.; Lavrova, A.V.; Surkov, S.A.; Mingazov, E.R.; Gretskaya, N.M.; Bezuglov, V.V.; Ugrumov, M.V. A New Method for the Visualization of Living Dopaminergic Neurons and Prospects for Using It to Develop Targeted Drug Delivery to These Cells. International Journal of Molecular Sciences, 2022, 23(7), 3678. doi: 10.3390/ijms23073678
  378. Sun, J.; Antczak, N.M.; Gahlon, H.L.; Sturla, S.J. Molecular beacons with oxidized bases report on substrate specificity of DNA oxoguanine glycosylases. Chemical Science, 2022, 13(15), 4295-4302. doi: 10.1039/d1sc05648d
  379. Chiu, S.-H.; Ho, W.-L.; Sun, Y.-C.; Kuo, J.-C.; Huang, J.-. Phase separation driven by interchangeable properties in the intrinsically disordered regions of protein paralogs. Communications Biology, 2022, 5, 400. doi: 10.1038/s42003-022-03354-4
  380. Ferguson, T.E.G.; Reihill, J.A.; Martin, S.L.; Walker, B. Novel Inhibitors and Activity-Based Probes Targeting Trypsin-Like Serine Proteases. Frontiers in Chemistry, 2022, 10, 782608. doi: 10.3389/fchem.2022.782608
  381. Mu, J.; Li, C.; Shi, Y.; Liu, G.; Zou, J.; Zhang, D.-Y.; Jiang, C.; Wang, X.; He, L.; Huang, P.; Yin, Y.; Chen, X. Protective effect of platinum nano-antioxidant and nitric oxide against hepatic ischemia-reperfusion injury. Nature Communications, 2022, 13, 2513. doi: 10.1038/s41467-022-29772-w
  382. Bragina, V.A.; Khomyakova, E.; Orlov, A.V.; Znoyko, S.L.; Mochalova, E.N.; Paniushkina, L.; Shender, V.O.; Erbes, T.; Evtushenko, E.G.; Bagrov, D.V.; Lavrenova, V.N.; Nazarenko, I.; Nikitin, P.I. Highly Sensitive Nanomagnetic Quantification of Extracellular Vesicles by Immunochromatographic Strips: A Tool for Liquid Biopsy. Nanomaterials, 2022, 12(9), 1579. doi: 10.3390/nano12091579
  383. Zhu, Y.; Chen, Z.; Kim, S.N.; Gan, C.; Ryl, T.; Lesjak, M.S.; Rodemerk, J.; Zhong, R.D.; Wrede, K.; Dammann, P.; Sure, U. Characterization of Temozolomide Resistance Using a Novel Acquired Resistance Model in Glioblastoma Cell Lines. Cancers, 2022, 14(9), 2211. doi: 10.3390/cancers14092211
  384. Zashikhina, N.; Levit, M.; Dobrodumov, A.; Gladnev, S.; Lavrentieva, A.; Tennikova, T.; Korzhikova-Vlakh, E. Biocompatible Nanoparticles Based on Amphiphilic Random Polypeptides and Glycopolymers as Drug Delivery Systems. Polymers, 2022, 14(9), 1677. doi: 10.3390/polym14091677
  385. Pilipenko, I.; Korovkina, O.; Gubina, N.; Ekimova, V.; Ishutinova, A.; Korzhikova-Vlakh, E.; Tennikova, T.; Korzhikov-Vlakh, V. Random Copolymers of Lysine and Isoleucine for Efficient mRNA Delivery. International Journal of Molecular Sciences, 2022, 23(10), 5363. doi: 10.3390/ijms23105363
  386. Gusliakova, O.I.; Prikhozhdenko, E.S.; Plastun, V.O.; Mayorova, O.A.; Shushunova, N.A.; Abdurashitov, A.S.; Kulikov, O.A.; Abakumov, M.A.; Gorin, D.A.; Sukhorukov, G.B.; Sindeeva, O.A. Renal Artery Catheterization for Microcapsules’ Targeted Delivery to the Mouse Kidney. Pharmaceutics, 2022, 14(5), 1056. doi: 10.3390/pharmaceutics14051056
  387. Babich, O.; Dolganyuk, V.; Andreeva, A.; Katserov, D.; Matskova, L.; Ulrikh, E.; Ivanova, S.; Michaud, P.; Sukhikh, S. Isolation of Valuable Biological Substances from Microalgae Culture. Foods, 2022, 11(11), 1654. doi: 10.3390/foods11111654
  388. Ben-Uliel, S.F.; Zoabi, F.H.; Slavin, M.; Sibony-Benyamini, H.; Kalisman, N.; Qvit, N. De Novo Development of Mitochondria-Targeted Molecular Probes Targeting Pink1. International Journal of Molecular Sciences, 2022, 23(11), 6076. doi: 10.3390/ijms23116076
  389. Biaggne, A.; Spear, L.; Barcenas, G.; Ketteridge, M.; Kim, Y.C.; Melinger, J.S.; Knowlton, W.B.; Yurke, B.; Li, L. Data-Driven and Multiscale Modeling of DNA-Templated Dye Aggregates. Molecules, 2022, 27(11), 3456. doi: 10.3390/molecules27113456
  390. Bednarczyk, M.; Peters, J.K.; Kasprzyk, R.; Starek, J.; Warminski, M.; Spiewla, T.; Mugridge, J.S.; Gross, J.D.; Jemielity, J.; Kowalska, J. Fluorescence-Based Activity Screening Assay Reveals Small Molecule Inhibitors of Vaccinia Virus mRNA Decapping Enzyme D9. ACS Chemical Biology, 2022, 17(6), 1460-1471. doi: 10.1021/acschembio.2c00049
  391. Manfredonia, A.J.; Kraut, D.A. The 26S Proteasome Switches between ATP-Dependent and -Independent Mechanisms in Response to Substrate Ubiquitination. Biomolecules, 2022, 12(6), 750. doi: 10.3390/biom12060750
  392. Mizuno, H.L.; Anraku, Y.; Sakuma, I.; Akagi, Y. Effect of PEGylation on the Drug Release Performance and Hemocompatibility of Photoresponsive Drug-Loading Platform. International Journal of Molecular Sciences, 2022, 23(12), 6686. doi: 10.3390/ijms23126686
  393. Zha, H.; Xu, Z.; Xu, X.; Lu, X.; Shi, P.; Xiao, Y.; Tsai, H.-I.; Su, D.; Cheng, F.; Cheng, X.; Chen, H. PD-1 Cellular Nanovesicles Carrying Gemcitabine to Inhibit the Proliferation of Triple Negative Breast Cancer Cell. Pharmaceutics, 2022, 14(6), 1263. doi: 10.3390/pharmaceutics14061263
  394. Kok, Z.Y.; Stoddart, L.A.; Mistry, S.J.; Mocking, T.A.M.; Vischer, H.F.; Leurs, R.; Hill, S.J.; Mistry, S.N.; Kellam, B. Optimization of Peptide Linker-Based Fluorescent Ligands for the Histamine H 1 Receptor. Journal of Medicinal Chemistry, 2022, 65(12), 8258-8288. doi: 10.1021/acs.jmedchem.2c00125
  395. van Leeuwen, W.; VanInsberghe, M.; Battich, N.; Salmén, F.; van Oudenaarden, A.; Rabouille, C. Identification of the stress granule transcriptome via RNA-editing in single cells and in vivo. Cell Reports Methods, 2022, 2(6), 100235. doi: 10.1016/j.crmeth.2022.100235
  396. Zhdanov, G.; Nyhrikova, E.; Meshcheryakova, N.; Kristavchuk, O.; Akhmetova, A.; Andreev, E.; Rudakova, E.; Gambaryan, A.; Yaminsky, I.; Aralov, A.; Kukushkin, V.; Zavyalova, E. A Combination of Membrane Filtration and Raman-Active DNA Ligand Greatly Enhances Sensitivity of SERS-Based Aptasensors for Influenza A Virus. Frontiers in Chemistry, 2022, 10, 937180. doi: 10.3389/fchem.2022.937180
  397. Zhao, M.; Zhang, M.; Xu, K.; Wu, K.; Xie, R.; Li, R.; Wang, Q.; Liu, W.; Wang, W.; Wang, X. Antimicrobial Effect of Extracellular Vesicles Derived From Human Oral Mucosal Epithelial Cells on Candida albicans. Frontiers in Immunology, 2022, 13, 777613. doi: 10.3389/fimmu.2022.777613
  398. Mikroulis, A.; Ledri, M.; Ruffolo, G.; Palma, E.; Sperk, G.; Dalli, J.; Vezzani, A.; Kokaia, M. Lipid mediator n‐3 docosapentaenoic acid‐derived protectin D1 enhances synaptic inhibition of hippocampal principal neurons by interaction with a G‐protein‐coupled receptor. The FASEB Journal, 2022, 36(3), e22203. doi: 10.1096/fj.202101815R
  399. Gorina, S.S.; Iljina, T.M.; Mukhtarova, L.S.; Toporkova, Y.Y.; Grechkin, A.N. Detection of Unprecedented CYP74 Enzyme in Mammal: Hydroperoxide Lyase CYP74C44 of the Bat Sturnira hondurensis. International Journal of Molecular Sciences, 2022, 23(14), 8009. doi: 10.3390/ijms23148009
  400. Areny-Balagueró, A.; Mekseriwattana, W.; Camprubí-Rimblas, M.; Stephany, A.; Roldan, A.; Solé-Porta, A.; Artigas, A.; Closa, D.; Roig, A. Fluorescent PLGA Nanocarriers for Pulmonary Administration: Influence of the Surface Charge. Pharmaceutics, 2022, 14(7), 1447. doi: 10.3390/pharmaceutics14071447
  401. Shen, J.; Liu, C.; Yan, P.; Wang, M.; Guo, L.; Liu, S.; Chen, J.; Rosenholm, J.M.; Huang, H.; Wang, R.; Zhang, H. Helper T Cell (CD4 + ) Targeted Tacrolimus Delivery Mediates Precise Suppression of Allogeneic Humoral Immunity. Research, 2022, 2022, 9794235. doi: 10.34133/2022/9794235
  402. Khrenova, M.G.; Panova, T.V.; Rodin, V.A.; Kryakvin, M.A.; Lukyanov, D.A.; Osterman, I.A.; Zvereva, M.I. Nanopore Sequencing for De Novo Bacterial Genome Assembly and Search for Single-Nucleotide Polymorphism. International Journal of Molecular Sciences, 2022, 23(15), 8569. doi: 10.3390/ijms23158569
  403. Díaz-Celis, C.; Cañari-Chumpitaz, C.; Sosa, R.P.; Castillo, J.P.; Zhang, M.; Cheng, E.; Chen, A.Q.; Vien, M.; Kim, J.H.; Onoa, B.; Bustamante, C. Assignment of structural transitions during mechanical unwrapping of nucleosomes and their disassembly products. Proceedings of the National Academy of Sciences of the United States of America, 2022, 119(33), e2206513119. doi: 10.1073/pnas.2206513119
  404. Chang, H.-W.; Feofanov, A.V.; Lyubitelev, A.V.; Armeev, G.A.; Kotova, E.Y.; Hsieh, F.-K.; Kirpichnikov, M.P.; Shaytan, A.K.; Studitsky, V.M. N-Terminal Tails of Histones H2A and H2B Differentially Affect Transcription by RNA Polymerase II In Vitro. Cells, 2022, 11(16), 2475. doi: 10.3390/cells11162475
  405. Saleh, B.; Srikanth, K.D.; Sneh, T.; Yue, L.; Pelech, S.; Elliott, E.; Gil-Henn, H. FAK-Mediated Signaling Controls Amyloid Beta Overload, Learning and Memory Deficits in a Mouse Model of Alzheimer’s Disease. International Journal of Molecular Sciences, 2022, 23(16), 9055. doi: 10.3390/ijms23169055
  406. Vasilev, R.; Gunitseva, N.; Shebanova, R.; Korzhenkov, A.; Vlaskina, A.; Evteeva, M.; Polushkina, I.; Nikitchina, N.; Toshchakov, S.; Kamenski, P.; Patrushev, M.; Mazunin, I. Targeted Modification of Mammalian DNA by a Novel Type V Cas12a Endonuclease from Ruminococcus bromii. International Journal of Molecular Sciences, 2022, 23(16), 9289. doi: 10.3390/ijms23169289
  407. Soffer, A.; Mahly, A.; Padmanabhan, K.; Cohen, J.; Adir, O.; Loushi, E.; Fuchs, Y.; Williams, S.E.; Luxenburg, C. Apoptosis and tissue thinning contribute to symmetric cell division in the developing mouse epidermis in a nonautonomous way. PLoS Biology, 2022, 20(8), e3001756. doi: 10.1371/journal.pbio.3001756
  408. Liu, X.; Cao, Z.; Liu, N.; Gao, G.; Du, M.; Wang, Y.; Cheng, B.; Zhu, M.; Jia, B.; Pan, L.; Zhang, W.; Jiang, Y.; He, W.; Xu, L.; Zhang, W.; An, Q.; Guo, Q.; Gu, J. Kill two birds with one stone: Engineered exosome-mediated delivery of cholesterol modified YY1-siRNA enhances chemoradiotherapy sensitivity of glioblastoma. Frontiers in Pharmacology, 2022, 13, 975291. doi: 10.3389/fphar.2022.975291
  409. Nojima, S.; Ishida, S.; Terayama, K.; Matsumoto, K.; Matsui, T.; Tahara, S.; Ohshima, K.; Kiyokawa, H.; Kido, K.; Ukon, K.; Yoshida, S.Y.; Mitani, T.T.; Doki, Y.; Mizushima, T.; Okuno, Y.; Susaki, E.A.; Ueda, H.R.; Morii, E. A Novel Three-Dimensional Imaging System Based on Polysaccharide Staining for Accurate Histopathological Diagnosis of Inflammatory Bowel Diseases. Cellular and Molecular Gastroenterology and Hepatology, 2022, 14(4), 905-924. doi: 10.1016/j.jcmgh.2022.07.001
  410. Medley, B.J.; Leclaire, L.; Thompson, N.; Mahoney, K.E.; Pluvinage, B.; Parson, M.A.H.; Burke, J.E.; Malaker, S.; Wakarchuk, W.; Boraston, A.B. A previously uncharacterized O -glycopeptidase from Akkermansia muciniphila requires the Tn-antigen for cleavage of the peptide bond. The Journal of Biological Chemistry, 2022, 298(10), 102439. doi: 10.1016/j.jbc.2022.102439
  411. Liu, N.; Liang, X.; Yang, C.; Hu, S.; Luo, Q.; Luo, H. Dual-targeted magnetic mesoporous silica nanoparticles reduce brain amyloid-β burden via depolymerization and intestinal metabolism. Theranostics, 2022, 12(15), 6646-6664. doi: 10.7150/thno.76574
  412. Khadria, A.; Paavola, C.D.; Zhang, Y.; Davis, S.P.X.; Grealish, P.F.; Maslov, K.; Shi, J.; Beals, J.M.; Oladipupo, S.S.; Wang, L.V. Long‐Duration and Non‐Invasive Photoacoustic Imaging of Multiple Anatomical Structures in a Live Mouse Using a Single Contrast Agent. Advanced Science, 2022, 9(28), 2202907. doi: 10.1002/advs.202202907
  413. Lobov, A.A.; Boyarskaya, N.V.; Kachanova, O.S.; Gromova, E.S.; Shishkova, A.A.; Zainullina, B.R.; Pishchugin, A.S.; Filippov, A.A.; Uspensky, V.E.; Malashicheva, A.B. Crenigacestat (LY3039478) inhibits osteogenic differentiation of human valve interstitial cells from patients with aortic valve calcification in vitro. Frontiers in Cardiovascular Medicine, 2022, 9, 969096. doi: 10.3389/fcvm.2022.969096
  414. Rennick, J.J.; Nowell, C.J.; Pouton, C.W.; Johnston, A.P.R. Resolving subcellular pH with a quantitative fluorescent lifetime biosensor. Nature Communications, 2022, 13, 6023. doi: 10.1038/s41467-022-33348-z
  415. Malinina, D.K.; Sivkina, A.L.; Korovina, A.N.; McCullough, L.L.; Formosa, T.; Kirpichnikov, M.P.; Studitsky, V.M.; Feofanov, A.V. Hmo1 Protein Affects the Nucleosome Structure and Supports the Nucleosome Reorganization Activity of Yeast FACT. Cells, 2022, 11(19), 2931. doi: 10.3390/cells11192931
  416. Yun, W.S.; Shim, M.K.; Lim, S.; Song, S.; Kim, J.; Yang, S.; Hwang, H.S.; Kim, M.R.; Yoon, H.Y.; Lim, D.-K.; Sun, I.-C.; Kim, K. Mesenchymal Stem Cell-Mediated Deep Tumor Delivery of Gold Nanorod for Photothermal Therapy. Nanomaterials, 2022, 12(19), 3410. doi: 10.3390/nano12193410
  417. Hu, R.; Yang, Y.; Song, G.; Zhao, F.; Chen, S.; Zhou, Z.; Zheng, J.; Shen, W. In vivo targeting capacities of different nanoparticles to prostate tissues based on a mouse model of chronic bacterial prostatitis. Frontiers in Bioengineering and Biotechnology, 2022, 10, 1021385. doi: 10.3389/fbioe.2022.1021385
  418. Moreno-Echeverri, A.M.; Susnik, E.; Vanhecke, D.; Taladriz-Blanco, P.; Balog, S.; Petri-Fink, A.; Rothen-Rutishauser, B. Pitfalls in methods to study colocalization of nanoparticles in mouse macrophage lysosomes. Journal of Nanobiotechnology, 2022, 20, 464. doi: 10.1186/s12951-022-01670-9
  419. Kraemer, S.A.; Barbosa da Costa, N.; Oliva, A.; Huot, Y.; Walsh, D.A. A resistome survey across hundreds of freshwater bacterial communities reveals the impacts of veterinary and human antibiotics use. Frontiers in Microbiology, 2022, 13, 995418. doi: 10.3389/fmicb.2022.995418
  420. Kosolapova, A.O.; Belousov, M.V.; Sulatsky, M.I.; Tsyganova, A.V.; Sulatskaya, A.I.; Bobylev, A.G.; Shtark, O.Y.; Tsyganov, V.E.; Volkov, K.V.; Zhukov, V.A.; Tikhonovich, I.A.; Nizhnikov, A.A. RopB protein of Rhizobium leguminosarum bv. viciae adopts amyloid state during symbiotic interactions with pea ( Pisum sativum L.). Frontiers in Plant Science, 2022, 13, 1014699. doi: 10.3389/fpls.2022.1014699
  421. Sukhanova, M.V.; Anarbaev, R.O.; Maltseva, E.A.; Pastré, D.; Lavrik, O.I. FUS Microphase Separation: Regulation by Nucleic Acid Polymers and DNA Repair Proteins. International Journal of Molecular Sciences, 2022, 23(21), 13200. doi: 10.3390/ijms232113200
  422. Mal’tseva, V.N.; Gudkov, S.V.; Turovsky, E.A. Modulation of the Functional State of Mouse Neutrophils by Selenium Nanoparticles In Vivo. International Journal of Molecular Sciences, 2022, 23(21), 13651. doi: 10.3390/ijms232113651
  423. Maluchenko, N.; Koshkina, D.; Korovina, A.; Studitsky, V.; Feofanov, A. Interactions of PARP1 Inhibitors with PARP1-Nucleosome Complexes. Cells, 2022, 11(21), 3343. doi: 10.3390/cells11213343
  424. Miranda, A.; Lopez-Blanco, R.; Lopes-Nunes, J.; Melo, A.M.; Campello, M.P.C.; Paulo, A.; Oliveira, M.C.; Mergny, J.-L.; Oliveira, P.A.; Fernandez-Megia, E.; Cruz, C. Gallic Acid–Triethylene Glycol Aptadendrimers Synthesis, Biophysical Characterization and Cellular Evaluation. Pharmaceutics, 2022, 14(11), 2456. doi: 10.3390/pharmaceutics14112456
  425. Slastnikova, T.A.; Rosenkranz, A.A.; Ulasov, A.V.; Khramtsov, Y.V.; Lupanova, T.N.; Georgiev, G.P.; Sobolev, A.S. Mouse Syngeneic Melanoma Model with Human Epidermal Growth Factor Receptor Expression. Pharmaceutics, 2022, 14(11), 2448. doi: 10.3390/pharmaceutics14112448
  426. Gordon-Kim, C.; Rha, A.; Poppitz, G.A.; Smith-Carpenter, J.; Luu, R.; Roberson, A.B.; Conklin, R.; Blake, A.; Lynn, D.G. Polyanion order controls liquid-to-solid phase transition in peptide/nucleic acid co-assembly. Frontiers in Molecular Biosciences, 2022, 9, 991728. doi: 10.3389/fmolb.2022.991728
  427. Brassington, K.; Kanellakis, P.; Cao, A.; Toh, B.-H.; Peter, K.; Bobik, A.; Kyaw, T. Crosstalk between cytotoxic CD8+ T cells and stressed cardiomyocytes triggers development of interstitial cardiac fibrosis in hypertensive mouse hearts. Frontiers in Immunology, 2022, 13, 1040233. doi: 10.3389/fimmu.2022.1040233
  428. Yu, W.; Bosquée, E.; Fan, J.; Liu, Y.; Bragard, C.; Francis, F.; Chen, J. Proteomic and Transcriptomic Analysis for Identification of Endosymbiotic Bacteria Associated with BYDV Transmission Efficiency by Sitobion miscanthi. Plants, 2022, 11(23), 3352. doi: 10.3390/plants11233352
  429. Antonova, L.; Kutikhin, A.; Sevostianova, V.; Lobov, A.; Repkin, E.; Krivkina, E.; Velikanova, E.; Mironov, A.; Mukhamadiyarov, R.; Senokosova, E.; Khanova, M.; Shishkova, D.; Markova, V.; Barbarash, L. Controlled and Synchronised Vascular Regeneration upon the Implantation of Iloprost- and Cationic Amphiphilic Drugs-Conjugated Tissue-Engineered Vascular Grafts into the Ovine Carotid Artery: A Proteomics-Empowered Study. Polymers, 2022, 14(23), 5149. doi: 10.3390/polym14235149
  430. Shishkova, D.; Lobov, A.; Zainullina, B.; Matveeva, V.; Markova, V.; Sinitskaya, A.; Velikanova, E.; Sinitsky, M.; Kanonykina, A.; Dyleva, Y.; Kutikhin, A. Calciprotein Particles Cause Physiologically Significant Pro-Inflammatory Response in Endothelial Cells and Systemic Circulation. International Journal of Molecular Sciences, 2022, 23(23), 14941. doi: 10.3390/ijms232314941
  431. Trac, N.; Oh, H.S.; Jones, L.I.; Caliliw, R.; Ohtake, S.; Shuch, B.; Chung, E.J. CD70-Targeted Micelles Enhance HIF2α siRNA Delivery and Inhibit Oncogenic Functions in Patient-Derived Clear Cell Renal Carcinoma Cells. Molecules, 2022, 27(23), 8457. doi: 10.3390/molecules27238457
  432. Wu, B.; Zhang, X.; Hu, K.; Zheng, H.; Zhang, S.; Liu, X.; Ma, M.; Zhao, H. Two alternative splicing variants of a wheat gene TaNAK1 , TaNAK1.1 and TaNAK1.2 , differentially regulate flowering time and plant architecture leading to differences in seed yield of transgenic Arabidopsis. Frontiers in Plant Science, 2022, 13, 1014176. doi: 10.3389/fpls.2022.1014176
  433. Fangue-Yapseu, G.Y.; Tola, A.J.; Missihoun, T.D. Proteome-wide analysis of hydrogen peroxide-induced protein carbonylation in Arabidopsis thaliana. Frontiers in Plant Science, 2022, 13, 1049681. doi: 10.3389/fpls.2022.1049681
  434. Koetemann, A.; Wollscheid, B. Apicobasal Surfaceome Architecture Encodes for Polarized Epithelial Functionality and Depends on Tumor Suppressor PTEN. International Journal of Molecular Sciences, 2022, 23(24), 16193. doi: 10.3390/ijms232416193
  435. Jonsson, E.; Htet, Z.M.; Bard, J.A.M.; Dong, K.C.; Martin, A. Ubiquitin modulates 26 S proteasome conformational dynamics and promotes substrate degradation. Science Advances, 2022, 8(51), eadd9520. doi: 10.1126/sciadv.add9520
  436. van Bergen, W.; Hevler, J.F.; Wu, W.; Baggelaar, M.P.; Heck, A.J.R. Site-Specific Activity-Based Protein Profiling Using Phosphonate Handles. Molecular & Cellular Proteomics, 2022, 22(1), 100455. doi: 10.1016/j.mcpro.2022.100455
  437. Yao, Y.; Wang, W.; Chen, C. Quantifying phase separation at the nanoscale by dual-color fluorescence cross-correlation spectroscopy (dcFCCS). Biophysics Reports, 2022, 8(1), 29-41. doi: 10.52601/bpr.2022.210026
  438. Celias, D.P.; de Mingo Pulido, Á.; Ruffell, B. Detection of exogenous DNA uptake by murine dendritic cells. STAR Protocols, 2022, 3(3), 101464. doi: 10.1016/j.xpro.2022.101464
  439. Çetin, B.; O’Leary, S.E. mRNA- and factor-driven dynamic variability controls eIF4F-cap recognition for translation initiation. Nucleic Acids Research, 2022, 50(14), 8240-8261. doi: 10.1093/nar/gkac631
  440. Lin, W.; Lu, X.; Yang, H.; Huang, L.; Huang, W.; Tang, Y.; Liu, S.; Wang, H.; Zhang, Y. Metabolic heterogeneity protects metastatic mucosal melanomas cells from ferroptosis. International Journal of Molecular Medicine, 2022, 50(4), 124. doi: 10.3892/ijmm.2022.5180
  441. Gaitan, B.; Frankle, L.; Vig, S.; Oskoui, E.; Adwan, M.; Chen, Y.; Elespuru, R.; Huang, H.‐C.; Pfefer, T.J. Quantifying the Photochemical Damage Potential of Contrast‐Enhanced Fluorescence Imaging Products: Singlet Oxygen Production. Photochemistry and photobiology, 2022, 98(4), 736-747. doi: 10.1111/php.13638
  442. Lee, A.; Sousa de Almeida, M.; Milinkovic, D.; Septiadi, D.; Taladriz-Blanco, P.; Loussert-Fonta, C.; Balog, S.; Bazzoni, A.; Rothen-Rutishauser, B.; Petri-Fink, A. Substrate stiffness reduces particle uptake by epithelial cells and macrophages in a size-dependent manner through mechanoregulation. Nanoscale, 2022, 14(40), 15141-15155. doi: 10.1039/d2nr03792k
  443. Bordat, A.; Boissenot, T.; Ibrahim, N.; Ferrere, M.; Levêque, M.; Potiron, L.; Denis, S.; Garcia-Argote, S.; Carvalho, O.; Abadie, J.; Cailleau, C.; Pieters, G.; Tsapis, N.; Nicolas, J. A Polymer Prodrug Strategy to Switch from Intravenous to Subcutaneous Cancer Therapy for Irritant/Vesicant Drugs. Journal of the American Chemical Society, 2022, 144(41), 18844-18860. doi: 10.1021/jacs.2c04944
  444. Coninx, S.; Kalot, G.; Godard, A.; Bodio, E.; Goze, C.; Sancey, L.; Auzély-Velty, R. Tailored hyaluronic acid-based nanogels as theranostic boron delivery systems for boron neutron cancer therapy. International Journal of Pharmaceutics: X, 2022, 4, 100134. doi: 10.1016/j.ijpx.2022.100134
  445. Wijesundara, Y.H.; Herbert, F.C.; Trashi, O.; Trashi, I.; Brohlin, O.R.; Kumari, S.; Howlett, T.; Benjamin, C.E.; Shahrivarkevishahi, A.; Diwakara, S.D.; Perera, S.D.; Cornelius, S.A.; Vizuet, J.P.; Balkus, K.J.; Smaldone, R.A.; De Nisco, N.J.; Gassensmith, J.J. Carrier gas triggered controlled biolistic delivery of DNA and protein therapeutics from metal–organic frameworks. Chemical Science, 2022, 13(46), 13803-13814. doi: 10.1039/d2sc04982a
  446. Komina, A.; Krasnikov, N.; Kucheruk, O.; Zhukova, E.; Yuzhakov, A.; Gulyukin, A. Distribution and genetic diversity of Feline calicivirus in Moscow metropolitan area. Journal of Veterinary Science, 2022, 23(6), e92. doi: 10.4142/jvs.22182
  447. Poyton, M.F.; Feng, X.A.; Ranjan, A.; Lei, Q.; Wang, F.; Zarb, J.S.; Louder, R.K.; Park, G.; Jo, M.H.; Ye, J.; Liu, S.; Ha, T.; Wu, C. Coordinated DNA and histone dynamics drive accurate histone H2A.Z exchange. Science Advances, 2022, 8(10), eabj5509. doi: 10.1126/sciadv.abj5509
  448. Grazon, C.; Chern, M.; Lally, P.; Baer, R.C.; Fan, A.; Lecommandoux, S.; Klapperich, C.; Dennis, A.M.; Galagan, J.E.; Grinstaff, M.W. The quantum dot vs. organic dye conundrum for ratiometric FRET-based biosensors: which one would you chose?. Chemical Science, 2022, 13(22), 6715-6731. doi: 10.1039/d1sc06921g
  449. Straehla, J.P.; Hajal, C.; Safford, H.C.; Offeddu, G.S.; Boehnke, N.; Dacoba, T.G.; Wyckoff, J.; Kamm, R.D.; Hammond, P.T. A predictive microfluidic model of human glioblastoma to assess trafficking of blood–brain barrier-penetrant nanoparticles. Proceedings of the National Academy of Sciences of the United States of America, 2022, 119(23), e2118697119. doi: 10.1073/pnas.2118697119
  450. Zhang, M.; Wang, L.; Liu, J.; Pang, Y. Envelope virus-mimetic nanovaccines by hybridizing bioengineered cell membranes with bacterial vesicles. iScience, 2022, 25(6), 104490. doi: 10.1016/j.isci.2022.104490
  451. Modrzycka, S.; Kołt, S.; Polderdijk, S.G.I.; Adams, T.E.; Potoczek, S.; Huntington, J.A.; Kasperkiewicz, P.; Drąg, M. Parallel imaging of coagulation pathway proteases activated protein C, thrombin, and factor Xa in human plasma. Chemical Science, 2022, 13(23), 6813-6829. doi: 10.1039/d2sc01108e
  452. Lee, H.J.; Gari, M.K.; Inman, D.R.; Rosenkrans, Z.T.; Burkel, B.M.; Olson, A.P.; Engle, J.W.; Hernandez, R.; Ponik, S.M.; Kwon, G.S. Multimodal Imaging Demonstrates Enhanced Tumor Exposure of PEGylated FUD Peptide in Breast Cancer. Journal of controlled release : official journal of the Controlled Release Society, 2022, 350, 284-297. doi: 10.1016/j.jconrel.2022.08.028
  453. Newman, H.; Hoque, J.; Shih, Y.-R.V.; Marushack, G.; Ko, U.; Gonzales, G.; Varghese, S. pH-Sensitive Nanocarrier Assisted Delivery of Adenosine to Treat Osteoporotic Bone Loss. Biomaterials Science, 2022, 10(18), 5340-5355. doi: 10.1039/d2bm00843b
  454. Gambles, M.T.; Li, J.; Radford, D.C.; Sborov, D.; Shami, P.; Yang, J.; Kopeček, J. Simultaneous crosslinking of CD20 and CD38 receptors by drug-free macromolecular therapeutics enhances B cell apoptosis in vitro and in vivo. Journal of controlled release : official journal of the Controlled Release Society, 2022, 350, 584-599. doi: 10.1016/j.jconrel.2022.08.045
  455. Fleming, A.M.; Xiao, S.; Chabot, M.B.; Burrows, C.J. Fluorophore-mediated Photooxidation of the Guanine Heterocycle. Journal of physical organic chemistry, 2022, 35(11), e4325. doi: 10.1002/poc.4325
  456. Vijayakumar, S.; Nasr, S.H.; Davis, J.E.; Wang, E.; Zuidema, J.M.; Lu, Y.-S.; Lo, Y.-H.; Sicklick, J.K.; Sailor, M.J.; Ray, P. Anti-KIT DNA Aptamer-conjugated Porous Silicon Nanoparticles for the Targeted Detection of Gastrointestinal Stromal Tumors. Nanoscale, 2022, 14(47), 17700-17713. doi: 10.1039/d2nr03905b
  457. Subrahmanyam, N.; Yathavan, B.; Kessler, J.; Yu, S.M.; Ghandehari, H. HPMA copolymer-collagen hybridizing peptide conjugates targeted to breast tumor extracellular matrix. Journal of controlled release : official journal of the Controlled Release Society, 2022, 353, 278-288. doi: 10.1016/j.jconrel.2022.10.017
  458. Mayère, C.; Regard, V.; Perea-Gomez, A.; Bunce, C.; Neirijnck, Y.; Djari, C.; Bellido-Carreras, N.; Sararols, P.; Reeves, R.; Greenaway, S.; Simon, M.; Siggers, P.; Condrea, D.; Kühne, F.; Gantar, I.; Tang, F.; Stévant, I.; Batti, L.; Ghyselinck, N.B.; Wilhelm, D.; Greenfield, A.; Capel, B.; Chaboissier, M.-C.; Nef, S. Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonad. Science Advances, 2022, 8(21), eabm0972. doi: 10.1126/sciadv.abm0972
  459. Banjade, S.; Zhu, L.; Jorgensen, J.R.; Suzuki, S.W.; Emr, S.D. Recruitment and organization of ESCRT-0 and ubiquitinated cargo via condensation. Science Advances, 2022, 8(13), eabm5149. doi: 10.1126/sciadv.abm5149

2021

  1. McDowell, C.T.; Klamer, Z.; Hall, J.; West, C.A.; Wisniewski, L.; Powers, T.W.; Angel, P.M.; Mehta, A.S.; Lewin, D.N.; Haab, B.B.; Drake, R.R. Imaging Mass Spectrometry and Lectin Analysis of N-Linked Glycans in Carbohydrate Antigen–Defined Pancreatic Cancer Tissues. Molecular & Cellular Proteomics, 2021, 20, 100012. doi: 10.1074/mcp.RA120.002256
  2. Ju, Y.; Edman, M.C.; Guo, H.; Janga, S.R.; Peddi, S.; Louie, S.G.; Junge, J.A.; MacKay, J.A.; Hamm-Alvarez, S.F. Intra-lacrimal Sustained Delivery of Rapamycin Shows Therapeutic Effects Without Systemic Toxicity in a Mouse Model of Autoimmune Dacryoadenitis Characteristic of Sjögren’s Syndrome. Biomacromolecules, 2021, 22(3), 1102-1114. doi: 10.1021/acs.biomac.0c01468
  3. Gmeiner, W.H.; Dominijanni, A.; Haber, A.O.; Ghiraldeli, L.P.; Caudell, D.L.; D’Agostino, R.; Pasche, B.C.; Smith, T.L.; Deng, Z.; Kiren, S.; Mani, C.; Palle, K.; Brody, J.R. Improved anti-Tumor Activity of the Fluoropyrimidine Polymer CF10 in pre-Clinical Colorectal Cancer Models thru Distinct Mechanistic and Pharmacological Properties. Molecular Cancer Therapeutics, 2021, 20(3), 553-563. doi: 10.1158/1535-7163.MCT-20-0516
  4. Feng, H.-Y.; Yuan, Y.; Zhang, Y.; Liu, H.-J.; Dong, X.; Yang, S.-C.; Liu, X.-L.; Lai, X.; Zhu, M.-H.; Wang, J.; Lu, Q.; Lin, Q.; Chen, H.-Z.; Lovell, J. F.; Sun, P.; Fang, C. Targeted Micellar Phthalocyanine for Lymph Node Metastasis Homing and Photothermal Therapy in an Orthotopic Colorectal Tumor Model. Nano-Micro Lett., 2021, 13(1), 145. doi: 10.1007/s40820-021-00666-8
  5. Song, Z.; Gremminger, T.; Singh, G.; Cheng, Y.; Li, J.; Qiu, L.; Ji, J.; Lange, M. J.; Zuo, X.; Chen, S.-J.; Zou, X.; Boris-Lawrie, K.; Heng, X. The Three-Way Junction Structure of the HIV-1 PBS-Segment Binds Host Enzyme Important for Viral Infectivity. Nucleic Acids Research, 2021, 49(10), 5925–5942. doi: 10.1093/nar/gkab342
  6. Zharinov, G. M.; Khalchitsky, S. E.; Loktionov, A.; Sogoyan, M. V.; Khutoryanskaya, Y. V.; Neklasova, N. Y.; Bogomolov, O. A.; Smirnov, I. V.; Samoilovich, M. P.; Skakun, V. N.; Vissarionov, S. V.; Anisimov, V. N. The Presence of Polymorphisms in Genes Controlling Neurotransmitter Metabolism and Disease Prognosis in Patients with Prostate Cancer: A Possible Link with Schizophrenia. Oncotarget, 2021, 12(7), 698–707. doi: 10.18632/oncotarget.27921
  7. Kim, K. R.; You, S. J.; Kim, H. J.; Yang, D. H.; Chun, H. J.; Lee, D.; Khang, G. Theranostic Potential of Biodegradable Polymeric Nanoparticles with Paclitaxel and Curcumin against Breast Carcinoma. Biomater. Sci., 2021, 9(10), 3750–3761. doi: 10.1039/D1BM00370D
  8. Li, R.; Ng, T. S. C.; Wang, S. J.; Prytyskach, M.; Rodell, C. B.; Mikula, H.; Kohler, R. H.; Garlin, M. A.; Lauffenburger, D. A.; Parangi, S.; Dinulescu, D. M.; Bardeesy, N.; Weissleder, R.; Miller, M. A. Therapeutically Reprogrammed Nutrient Signalling Enhances Nanoparticulate Albumin Bound Drug Uptake and Efficacy in KRAS-Mutant Cancer. Nat. Nanotechnol., 2021, 16(7), 830–839. doi: 10.1038/s41565-021-00897-1
  9. Garry, G. A.; Bezprozvannaya, S.; Chen, K.; Zhou, H.; Hashimoto, H.; Morales, M. G.; Liu, N.; Bassel-Duby, R.; Olson, E. N. The Histone Reader PHF7 Cooperates with the SWI/SNF Complex at Cardiac Super Enhancers to Promote Direct Reprogramming. Nat Cell Biol, 2021, 23(5), 467–475. doi: 10.1038/s41556-021-00668-z
  10. Zhang, T.; Fu, C.; Alradwan, I.; Yen, T.; Lip, H.; Cai, P.; Rauth, A. M.; Zhang, L.; Wu, X. Y. Targeting Signaling Pathways of Hyaluronic Acid and Integrin Receptors by Synergistic Combination Nanocomposites Inhibits Systemic Metastases and Primary Triple Negative Breast Cancer. Advanced Therapeutics, 2021, 4(6), 2100022. doi: 10.1002/adtp.202100022
  11. Biswas, S.; Wu, C.; van der Donk, W. A. The Antimicrobial Activity of the Glycocin Sublancin Is Dependent on an Active Phosphoenolpyruvate-Sugar Phosphotransferase System. ACS Infect. Dis., 2021, 7(8), 2402–2412. doi: 10.1021/acsinfecdis.1c00157
  12. Babi, M.; Riesco, R.; Boyer, L.; Fatona, A.; Accardo, A.; Malaquin, L.; Moran-Mirabal, J. Tuning the Nanotopography and Chemical Functionality of 3D Printed Scaffolds through Cellulose Nanocrystal Coatings. ACS Appl. Bio Mater., 2021, 4(12), 8443–8455. doi: 10.1021/acsabm.1c00970
  13. Kupryushkin, M. S.; Zharkov, T. D.; Ilina, E. S.; Markov, O. V.; Kochetkova, A. S.; Akhmetova, M. M.; Lomzov, A. A.; Pyshnyi, D. V.; Lavrik, O. I.; Khodyreva, S. N. Triazinylamidophosphate Oligonucleotides: Synthesis and Study of Their Interaction with Cells and DNA-Binding Proteins. Russ J Bioorg Chem, 2021, 47(3), 719–733. doi: 10.1134/S1068162021030110
  14. Shukla, S.; Marks, I.; Church, D.; Chan, S.-K.; K. Pokorski, J.; F. Steinmetz, N. Tobacco Mosaic Virus for the Targeted Delivery of Drugs to Cells Expressing Prostate-Specific Membrane Antigen. RSC Advances, 2021, 11(33), 20101–20108. doi: 10.1039/D1RA03166J
  15. Ha, L.; Choi, K. M.; Kim, D.-P. Interwoven MOF-Coated Janus Cells as a Novel Carrier of Toxic Proteins. ACS Appl. Mater. Interfaces, 2021, 13(16), 18545–18553. doi: 10.1021/acsami.1c01927
  16. Leiske, M. N.; Lai, M.; Amarasena, T.; Davis, T. P.; Thurecht, K. J.; Kent, S. J.; Kempe, K. Biomaterials. Interactions of Core Cross-Linked Poly(2-Oxazoline) and Poly(2-Oxazine) Micelles with Immune Cells in Human Blood, 2021, 274, 120843. doi: 10.1016/j.biomaterials.2021.120843
  17. Mu, W.; Li, S.; Xu, J.; Guo, X.; Wu, H.; Chen, Z.; Qiao, L.; Helfer, G.; Lu, F.; Liu, C.; Wu, Q.-F. Hypothalamic Rax+ Tanycytes Contribute to Tissue Repair and Tumorigenesis upon Oncogene Activation in Mice. Nat Commun, 2021, 12(1), 2288. doi: 10.1038/s41467-021-22640-z
  18. Lee, F.; Hyun Bae, K.; Ng, S.; Yamashita, A.; Kurisawa, M. Hyaluronic Acid–Green Tea Catechin Conjugates as a Potential Therapeutic Agent for Rheumatoid Arthritis. RSC Advances, 2021, 11(24), 14285–14294. doi: 10.1039/D1RA01491A
  19. Parayath, N. N.; Hong, B. V.; Mackenzie, G. G.; Amiji, M. M. Hyaluronic Acid Nanoparticle-Encapsulated MicroRNA-125b Repolarizes Tumor-Associated Macrophages in Pancreatic Cancer. Nanomedicine, 2021, 16(25), 2291–2303. doi: 10.2217/nnm-2021-0080
  20. Le, T.-N.; Lin, C.-J.; Shen, Y. C.; Lin, K.-Y.; Lee, C.-K.; Huang, C.-C.; Rao, N. V. Hyaluronic Acid Derived Hypoxia-Sensitive Nanocarrier for Tumor Targeted Drug Delivery. ACS Appl. Bio Mater., 2021, 4(12), 8325–8332. doi: 10.1021/acsabm.1c00847
  21. Rhodes, J. W.; Botting, R. A.; Bertram, K. M.; Vine, E. E.; Rana, H.; Baharlou, H.; Vegh, P.; O’Neil, T. R.; Ashhurst, A. S.; Fletcher, J.; Parnell, G. P.; Graham, J. D.; Nasr, N.; Lim, J. J. K.; Barnouti, L.; Haertsch, P.; Gosselink, M. P.; Di Re, A.; Reza, F.; Ctercteko, G.; Jenkins, G. J.; Brooks, A. J.; Patrick, E.; Byrne, S. N.; Hunter, E.; Haniffa, M. A.; Cunningham, A. L.; Harman, A. N. Human Anogenital Monocyte-Derived Dendritic Cells and Langerin+cDC2 Are Major HIV Target Cells. Nat Commun, 2021, 12(1), 2147. doi: 10.1038/s41467-021-22375-x
  22. Noskov, R.; Machnev, A.; Shishkin, I.; Novoselova, M.; Gaier, A.; Ezhov, A.; Shirshin, E.; German, S. V.; Rukhlenko, I.; Fleming, S.; Khlebtsov, B.; Gorin, D.; Ginzburg, P. Golden Vaterite as a Mesoscopic Metamaterial for Biophotonic Applications. Advanced Materials, 2021, 2008484. doi: 10.1002/adma.202008484
  23. Khawaja, R. R.; Agarwal, A.; Fukaya, M.; Jeong, H.-K.; Gross, S.; Gonzalez-Fernandez, E.; Soboloff, J.; Bergles, D. E.; Kang, S. H. GluA2 Overexpression in Oligodendrocyte Progenitors Promotes Postinjury Oligodendrocyte Regeneration. Cell Reports, 2021, 35(7), 109147. doi: 10.1016/j.celrep.2021.109147
  24. Hsu, C.-F.; Chang, K.-C.; Chen, Y.-L.; Hsieh, P.-S.; Lee, A.-I.; Tu, J.-Y.; Chen, Y.-T.; Wen, J.-D. Formation of Frameshift-Stimulating RNA Pseudoknots Is Facilitated by Remodeling of Their Folding Intermediates. Nucleic Acids Research, 2021, 49(12), 6941–6957. doi: 10.1093/nar/gkab512
  25. Zhang, S.; Li, G.; Deng, D.; Dai, Y.; Liu, Z.; Wu, S. Fluorinated Chitosan Mediated Synthesis of Copper Selenide Nanoparticles with Enhanced Penetration for Second Near-Infrared Photothermal Therapy of Bladder Cancer. Advanced Therapeutics, 2021, 4(7), 2100043. doi: 10.1002/adtp.202100043
  26. Bou, S.; Klymchenko, A. S.; Collot, M. Fluorescent Labeling of Biocompatible Block Copolymers: Synthetic Strategies and Applications in Bioimaging. Mater. Adv., 2021, 2(10), 3213–3233. doi: 10.1039/D1MA00110H
  27. Lin, J.-C.; Hsu, C.-Y.; Chen, J.-Y.; Fang, Z.-S.; Chen, H.-W.; Yao, B.-Y.; Shiau, G. H. M.; Tsai, J.-S.; Gu, M.; Jung, M.; Lee, T.-Y.; Hu, C.-M. J. Facile Transformation of Murine and Human Primary Dendritic Cells into Robust and Modular Artificial Antigen-Presenting Systems by Intracellular Hydrogelation. Advanced Materials, 2021, 33(30), 2101190. doi: 10.1002/adma.202101190
  28. Kim, C.; Shon, M. J.; Kim, S. H.; Eun, G. S.; Ryu, J.-K.; Hyeon, C.; Jahn, R.; Yoon, T.-Y. Extreme Parsimony in ATP Consumption by 20S Complexes in the Global Disassembly of Single SNARE Complexes. Nat Commun, 2021, 12(1), 3206. doi: 10.1038/s41467-021-23530-0
  29. Zhang, E.; Osipova, N.; Sokolov, M.; Maksimenko, O.; Semyonkin, A.; Wang, M.; Grigartzik, L.; Gelperina, S.; Sabel, B. A.; Henrich-Noack, P. Exploring the Systemic Delivery of a Poorly Water-Soluble Model Drug to the Retina Using PLGA Nanoparticles. European Journal of Pharmaceutical Sciences, 2021, 164, 105905. doi: 10.1016/j.ejps.2021.105905
  30. Hu, K.-W.; Fan, H.-F.; Lin, H.-C.; Huang, J.-W.; Chen, Y.-C.; Shen, C.-L.; Shih, Y.-H.; Tu, L.-H. Exploring the Impact of Glyoxal Glycation on β-Amyloid Peptide (Aβ) Aggregation in Alzheimer’s Disease. J. Phys. Chem. B, 2021, 125(21), 5559–5571. doi: 10.1021/acs.jpcb.1c02797
  31. Clark, H. R.; McKenney, C.; Livingston, N. M.; Gershman, A.; Sajjan, S.; Chan, I. S.; Ewald, A. J.; Timp, W.; Wu, B.; Singh, A.; Regot, S. Epigenetically Regulated Digital Signaling Defines Epithelial Innate Immunity at the Tissue Level. Nat Commun, 2021, 12(1), 1836. doi: 10.1038/s41467-021-22070-x
  32. Damavandi, F.; Wang, W.; Shen, W.-Z.; Cetinel, S.; Jordan, T.; Jovel, J.; Montemagno, C.; Wong, G. K.-S. Enrichment of Low Abundance DNA/RNA by Oligonucleotide-Clicked Iron Oxide Nanoparticles. Sci Rep, 2021, 11(1), 13053. doi: 10.1038/s41598-021-92376-9
  33. Jäger, E.; Humajová, J.; Dölen, Y.; Kučka, J.; Jäger, A.; Konefał, R.; Pankrác, J.; Pavlova, E.; Heizer, T.; Šefc, L.; Hrubý, M.; Figdor, C. G.; Verdoes, M. Enhanced Antitumor Efficacy through an “AND Gate” Reactive Oxygen-Species-Dependent PH-Responsive Nanomedicine Approach. Advanced Healthcare Materials, 2021, 10(13), 2100304. doi: 10.1002/adhm.202100304
  34. Pan, H.; Li, L.; Pang, G.; Han, C.; Liu, B.; Zhang, Y.; Shen, Y.; Sun, T.; Liu, J.; Chang, J.; Wang, H. Engineered NIR Light-Responsive Bacteria as Anti-Tumor Agent for Targeted and Precise Cancer Therapy. Chemical Engineering Journal, 2021, 426, 130842. doi: 10.1016/j.cej.2021.130842
  35. Yin, S.; Wang, Y.; Zhang, B.; Qu, Y.; Liu, Y.; Dai, S.; Zhang, Y.; Wang, Y.; Bi, J. Engineered Human Heavy-Chain Ferritin with Half-Life Extension and Tumor Targeting by PAS and RGDK Peptide Functionalization. Pharmaceutics, 2021, 13(4), 521. doi: 10.3390/pharmaceutics13040521
  36. Yan, Y.; Hernandez-Andrade, E.; Basij, M.; Alshahrani, S. S.; Kondle, S.; Brown, B. O.; Gelovani, J.; Hassan, S.; Hsu, C.-D.; Mehrmohammadi, M. Endocavity Ultrasound and Photoacoustic System for Fetal and Maternal Imaging: Design, Implementation, and Ex-Vivo Validation. JMI, 2021, 8(6), 066001. doi: 10.1117/1.JMI.8.6.066001
  37. Peplau, E.; De Rose, F.; Eichinger, A.; Reder, S.; Mittelhäuser, M.; Scafetta, G.; Schwaiger, M.; Weber, W. A.; Bartolazzi, A.; D’Alessandria, C.; Skerra, A. Effective Rational Humanization of a PASylated Anti-Galectin-3 Fab for the Sensitive PET Imaging of Thyroid Cancer in Vivo. Sci Rep, 2021, 11(1), 7358. doi: 10.1038/s41598-021-86641-0
  38. Min, K.; Yoo, S.; Han, M. S.; Tae, G. Effective and Prolonged Targeting of a Nanocarrier to the Inflammation Site by Functionalization with ZnBPMP and Chitosan. Materials Science and Engineering: C, 2021, 131, 112521. doi: 10.1016/j.msec.2021.112521
  39. Epanchintseva, A. V.; Gorbunova, E. A.; Ryabchikova, E. I.; Pyshnaya, I. A.; Pyshnyi, D. V. Effect of Fluorescent Labels on DNA Affinity for Gold Nanoparticles. Nanomaterials, 2021, 11(5), 1178. doi: 10.3390/nano11051178
  40. Ouali, R.; Vieira, L. R.; Salmon, D.; Bousbata, S. Early Post-Prandial Regulation of Protein Expression in the Midgut of Chagas Disease Vector Rhodnius Prolixus Highlights New Potential Targets for Vector Control Strategy. Microorganisms, 2021, 9(4), 804. doi: 10.3390/microorganisms9040804
  41. Lunn, A. M.; Unnikrishnan, M.; Perrier, S. Dual PH-Responsive Macrophage-Targeted Isoniazid Glycoparticles for Intracellular Tuberculosis Therapy. Biomacromolecules, 2021, 22(9), 3756–3768. doi: 10.1021/acs.biomac.1c00554
  42. Li, H.; Wang, Z.; Chen, Z.; Ci, T.; Chen, G.; Wen, D.; Li, R.; Wang, J.; Meng, H.; Bryan Bell, R.; Gu, Z.; Dotti, G.; Gu, Z. Disrupting Tumour Vasculature and Recruitment of APDL1-Loaded Platelets Control Tumour Metastasis. Nat Commun, 2021, 12(1), 2773. doi: 10.1038/s41467-021-22674-3
  43. Schmitner, N.; Recheis, C.; Thönig, J.; Kimmel, R. A. Differential Responses of Neural Retina Progenitor Populations to Chronic Hyperglycemia. Cells, 2021, 10(11), 3265. doi: 10.3390/cells10113265
  44. Donlin-Asp, P. G.; Polisseni, C.; Klimek, R.; Heckel, A.; Schuman, E. M. Differential Regulation of Local MRNA Dynamics and Translation Following Long-Term Potentiation and Depression. Proc Natl Acad Sci U S A, 2021, 118(13), e2017578118. doi: 10.1073/pnas.2017578118
  45. Trinh, P. N. H.; Chong, D. J. W.; Leach, K.; Hill, S. J.; Tyndall, J. D. A.; May, L. T.; Vernall, A. J.; Gregory, K. J. Development of Covalent, Clickable Probes for Adenosine A1 and A3 Receptors. J. Med. Chem., 2021, 64(12), 8161–8178. doi: 10.1021/acs.jmedchem.0c02169
  46. Wang, Y.; Li, Y.; Cao, J.; Meng, Q.; Li, X.; Zhang, Y.; Lam, K. S.; Hong, A.; Liu, R.; Chen, X. Development and Characterization of a Novel Peptide—Drug Conjugate with DM1 for Treatment of FGFR2-Positive Tumors. Biomedicines, 2021, 9(8), 849. doi: 10.3390/biomedicines9080849
  47. Sapozhnikova, K. A.; Misyurin, A. V.; Pestov, N. B.; Meleshkina, E. G.; Oreshkov, S. D.; Ganzhula, E. P.; Mikhailova, A. S.; Korshun, V. A.; Misyurin, V. A.; Brylev, V. A. Detection of the PRAME Protein on the Surface of Melanoma Cells Using a Fluorescently Labeled Monoclonal Antibody. Russ J Bioorg Chem, 2021, 47(5), 1077–1085. doi: 10.1134/S1068162021050332
  48. Park, J.; Wen, A. M.; Gao, H.; Shin, M. D.; Simon, D. I.; Wang, Y.; Steinmetz, N. F. Designing S100A9-Targeted Plant Virus Nanoparticles to Target Deep Vein Thrombosis. Biomacromolecules, 2021, 22(6), 2582–2594. doi: 10.1021/acs.biomac.1c00303
  49. Kim, S.-Y.; Han, G.; Hwang, D.-B.; Won, D.-H.; Shin, Y.-S.; Kim, C.; Kang, J. M.; Park, J.-H.; Jung, H.-D.; Park, W.; Yun, J.-W. Design and Usability Evaluations of a 3D-Printed Implantable Drug Delivery Device for Acute Liver Failure in Preclinical Settings. Advanced Healthcare Materials, 2021, 10(14), 2100497. doi: 10.1002/adhm.202100497
  50. Richard, E. T.; Morinaga, K.; Zheng, Y.; Sundberg, O.; Hokugo, A.; Hui, K.; Zhou, Y.; Sasaki, H.; Kashemirov, B. A.; Nishimura, I.; McKenna, C. E. Design and Synthesis of Cathepsin-K-Activated Osteoadsorptive Fluorogenic Sentinel (OFS) Probes for Detecting Early Osteoclastic Bone Resorption in a Multiple Myeloma Mouse Model. Bioconjugate Chem., 2021, 32(5), 916–927. doi: 10.1021/acs.bioconjchem.1c00036
  51. Chetverikov, P. E.; Fedorov, D. S.; Letukhova, V. Y.; Romanovich, A. E. Description of Cecidophyes Fibigiae n. Sp., New Combinations, Records, and DNA Barcodes of Eriophyid Mites (Eriophyoidea, Eriophyidae) from Karadag Nature Reserve (Crimea). Systematic and Applied Acarology, 2021, 26(4), 818-828. doi: 10.11158/saa.26.4.12
  52. Park, J. Y.; You, S. J.; Park, K.; Song, Y. J.; Park, J. S.; Yang, D. H.; Kim, J. K.; Chun, H. J.; Khang, G. Cyclic RGDfK- and Sulfo-Cy5.5-Functionalized MPEG-PCL Theranostic Nanosystems for Hepatocellular Carcinoma. Journal of Industrial and Engineering Chemistry, 2021, 99, 204–213. doi: 10.1016/j.jiec.2021.04.023
  53. Ortega-Rivera, O. A.; Shukla, S.; Shin, M. D.; Chen, A.; Beiss, V.; Moreno-Gonzalez, M. A.; Zheng, Y.; Clark, A. E.; Carlin, A. F.; Pokorski, J. K.; Steinmetz, N. F. Cowpea Mosaic Virus Nanoparticle Vaccine Candidates Displaying Peptide Epitopes Can Neutralize the Severe Acute Respiratory Syndrome Coronavirus. ACS Infect. Dis., 2021, 7(11), 3096–3110. doi: 10.1021/acsinfecdis.1c00410
  54. Bartlett, C.; Langsjoen, J.; Cheng, Q.; Yingling, A. V.; Weiss, M.; Bradfute, S.; Perkins, D. J.; Hurwitz, I. COVID-19 Global Pandemic Planning: Presence of SARS-CoV-2 Fomites in a University Hospital Setting. Exp Biol Med (Maywood), 2021, 246(18), 2039–2045. doi: 10.1177/15353702211024597
  55. Choi, S.; Zhang, B.; Ma, S.; Gonzalez-Celeiro, M.; Stein, D.; Jin, X.; Kim, S. T.; Kang, Y.-L.; Besnard, A.; Rezza, A.; Grisanti, L.; Buenrostro, J. D.; Rendl, M.; Nahrendorf, M.; Sahay, A.; Hsu, Y.-C. Corticosterone Inhibits GAS6 to Govern Hair Follicle Stem-Cell Quiescence. Nature, 2021, 592(7854), 428–432. doi: 10.1038/s41586-021-03417-2
  56. Bauer, T. A.; Horvat, N. K.; Marques, O.; Chocarro, S.; Mertens, C.; Colucci, S.; Schmitt, S.; Carrella, L. M.; Morsbach, S.; Koynov, K.; Fenaroli, F.; Blümler, P.; Jung, M.; Sotillo, R.; Hentze, M. W.; Muckenthaler, M. U.; Barz, M. Core Cross-Linked Polymeric Micelles for Specific Iron Delivery: Inducing Sterile Inflammation in Macrophages. Advanced Healthcare Materials, 2021, 10(19), 2100385. doi: 10.1002/adhm.202100385
  57. Scott, A. J.; Niitsu, A.; Kratochvil, H. T.; Lang, E. J. M.; Sengel, J. T.; Dawson, W. M.; Mahendran, K. R.; Mravic, M.; Thomson, A. R.; Brady, R. L.; Liu, L.; Mulholland, A. J.; Bayley, H.; DeGrado, W. F.; Wallace, M. I.; Woolfson, D. N. Constructing Ion Channels from Water-Soluble α-Helical Barrels. Nat. Chem., 2021, 13(7), 643–650. doi: 10.1038/s41557-021-00688-0
  58. Guan, J.; You, S.; Xiang, Y.; Schimelman, J.; Alido, J.; Ma, X.; Tang, M.; Chen, S. Compensating the Cell-Induced Light Scattering Effect in Light-Based Bioprinting Using Deep Learning. Biofabrication, 2021, 14(1), 015011. doi: 10.1088/1758-5090/ac3b92
  59. Borvinskaya, E.; Kochneva, A.; Bedulina, D.; Sukhovskaya, I.; Smirnov, L.; Babkina, I. Comparative Analysis of Proteins of Functionally Different Body Parts of the Fish Parasites Triaenophorus Nodulosus and Triaenophorus Crassus. Acta Parasit., 2021, 66(4), 1137–1150. doi: 10.1007/s11686-021-00384-6
  60. Kotova, A. V.; Lobov, A. A.; Dombrovskaya, J. A.; Sannikova, V. Y.; Ryumina, N. A.; Klausen, P.; Shavarda, A. L.; Malashicheva, A. B.; Enukashvily, N. I. Comparative Analysis of Dental Pulp and Periodontal Stem Cells: Differences in Morphology, Functionality, Osteogenic Differentiation and Proteome. Biomedicines, 2021, 9(11), 1606. doi: 10.3390/biomedicines9111606
  61. Co, C. M.; Izuagbe, S.; Zhou, J.; Zhou, N.; Sun, X.; Borrelli, J.; Tang, L. Click Chemistry-Based Pre-Targeting Cell Delivery for Cartilage Regeneration. Regenerative Biomaterials, 2021, 8(3), rbab018. doi: 10.1093/rb/rbab018
  62. Ji, D.; Lyu, K.; Zhao, H.; Kwok, C. K. Circular L-RNA Aptamer Promotes Target Recognition and Controls Gene Activity. Nucleic Acids Research, 2021, 49(13), 7280–7291. doi: 10.1093/nar/gkab593
  63. Merta, H.; Carrasquillo Rodríguez, J. W.; Anjur-Dietrich, M. I.; Vitale, T.; Granade, M. E.; Harris, T. E.; Needleman, D. J.; Bahmanyar, S. Cell Cycle Regulation of ER Membrane Biogenesis Protects against Chromosome Missegregation. Developmental Cell, 2021, 56(24), 3364-3379.e10. doi: 10.1016/j.devcel.2021.11.009
  64. Yang, H. Y.; Meng Du, J.; Jang, M.-S.; Mo, X. W.; Sun, X. S.; Lee, D. S.; Lee, J. H.; Fu, Y. CD44-Targeted and Enzyme-Responsive Photo-Cross-Linked Nanogels with Enhanced Stability for In Vivo Protein Delivery. Biomacromolecules, 2021, 22(8), 3590–3600. doi: 10.1021/acs.biomac.1c00653
  65. Kang, Y. K.; Lee, J.; Im, S. H.; Lee, J. H.; Jeong, J.; Kim, D. K.; Yang, S. Y.; Jung, K.; Kim, S.-G.; Chung, H. J. Cas9 Conjugate Complex Delivering Donor DNA for Efficient Gene Editing by Homology-Directed Repair. Journal of Industrial and Engineering Chemistry, 2021, 102, 241–250. doi: 10.1016/j.jiec.2021.07.009
  66. Hoque, J.; Shih, Y.-R. V.; Zeng, Y.; Newman, H.; Sangaj, N.; Arjunji, N.; Varghese, S. Bone Targeting Nanocarrier-Assisted Delivery of Adenosine to Combat Osteoporotic Bone Loss. Biomaterials, 2021, 273, 120819. doi: 10.1016/j.biomaterials.2021.120819
  67. Das, A.; Vishvakarma, V.; Dey, A.; Dey, S.; Gupta, A.; Das, M.; Vishwakarma, K. K.; Roy, D. S.; Yadav, S.; Kesarwani, S.; Venkatramani, R.; Maiti, S. Biophysical Properties of the Isolated Spike Protein Binding Helix of Human ACE2. Biophysical Journal, 2021, 120(14), 2785–2792. doi: 10.1016/j.bpj.2021.06.017
  68. Shin, M. D.; Hochberg, J. D.; Pokorski, J. K.; Steinmetz, N. F. Bioconjugation of Active Ingredients to Plant Viral Nanoparticles Is Enhanced by Preincubation with a Pluronic F127 Polymer Scaffold. ACS Appl. Mater. Interfaces, 2021, 13(50), 59618–59632. doi: 10.1021/acsami.1c13183
  69. Erokhina, T. N.; Ryazantsev, D. Yu.; Samokhvalova, L. V.; Mozhaev, A. A.; Orsa, A. N.; Zavriev, S. K.; Morozov, S. Yu. Activity of Chemically Synthesized Peptide Encoded by the MiR156A Precursor and Conserved in the Brassicaceae Family Plants. Biochemistry Moscow, 2021, 86(5), 551–562. doi: 10.1134/S0006297921050047
  70. Shramova, E. I.; Shilova, M. V.; Ryabova, A. V.; Dzhalilova, D. S.; Zolotova, N. A.; Telegin, G. B.; Deyev, S. M.; Proshkina, G. M. Barnase*Barstar-Guided Two-Step Targeting Approach for Drug Delivery to Tumor Cells in Vivo. Journal of Controlled Release, 2021, 340, 200–208. doi: 10.1016/j.jconrel.2021.11.001
  71. Goujon, G.; Baldim, V.; Roques, C.; Bia, N.; Seguin, J.; Palmier, B.; Graillot, A.; Loubat, C.; Mignet, N.; Margaill, I.; Berret, J.-F.; Beray-Berthat, V. Antioxidant Activity and Toxicity Study of Cerium Oxide Nanoparticles Stabilized with Innovative Functional Copolymers. Adv Healthcare Materials, 2021, 10(11), 2100059. doi: 10.1002/adhm.202100059
  72. Chen, K.; Si, Y.; Ou, J.; Guan, J.-S.; Kim, S.; Ernst, P.; Zhang, Y.; Zhou, L.; Han, X.; Liu, X. Antibody–Drug Conjugate to Treat Meningiomas. Pharmaceuticals, 2021, 14(5), 427. doi: 10.3390/ph14050427
  73. Si, Y.; Zhang, Y.; Guan, J.-S.; Ngo, H. G.; Totoro, A.; Singh, A. P.; Chen, K.; Xu, Y.; Yang, E. S.; Zhou, L.; Liu, R.; Liu, X. Anti-CD47 Monoclonal Antibody–Drug Conjugate: A Targeted Therapy to Treat Triple-Negative Breast Cancers. Vaccines, 2021, 9(8), 882. doi: 10.3390/vaccines9080882.
  74. Sun, Y. J.; Lin, C.-H.; Wu, M.-R.; Lee, S. H.; Yang, J.; Kunchur, C. R.; Mujica, E. M.; Chiang, B.; Jung, Y. S.; Wang, S.; Mahajan, V. B. An Intravitreal Implant Injection Method for Sustained Drug Delivery into Mouse Eyes. Cell Reports Methods, 2021, 1(8), 100125. doi: 10.1016/j.crmeth.2021.100125
  75. Chen, R.; Zhu, C.; Xu, L.; Gu, Y.; Ren, S.; Bai, H.; Zhou, Q.; Liu, X.; Lu, S.; Bi, X.; Li, W.; Jia, X.; Chen, Z. An Injectable Peptide Hydrogel with Excellent Self-Healing Ability to Continuously Release Salvianolic Acid B for Myocardial Infarction. Biomaterials, 2021, 274, 120855. doi: 10.1016/j.biomaterials.2021.120855
  76. Klein, K.; Loza, K.; Heggen, M.; Epple, M. An Efficient Method for Covalent Surface Functionalization of Ultrasmall Metallic Nanoparticles by Surface Azidation Followed by Copper-Catalyzed Azide-Alkyne Cycloaddition (Click Chemistry). ChemNanoMat, 2021, 7(12), 1330–1339. doi: 10.1002/cnma.202100359
  77. Li, L.; Huang, K.-L.; Gao, Y.; Cui, Y.; Wang, G.; Elrod, N. D.; Li, Y.; Chen, Y. E.; Ji, P.; Peng, F.; Russell, W. K.; Wagner, E. J.; Li, W. An Atlas of Alternative Polyadenylation Quantitative Trait Loci Contributing to Complex Trait and Disease Heritability. Nat Genet, 2021, 53(7), 994–1005. doi: 10.1038/s41588-021-00864-5
  78. Shirasu, T.; Yodsanit, N.; Xie, X.; Zhao, Y.; Wang, Y.; Xie, R.; Huang, Y.; Wang, B.; Urabe, G.; Gong, S.; Guo, L.-W.; Kent, K. C. An Adventitial Painting Modality of Local Drug Delivery to Abate Intimal Hyperplasia. Biomaterials, 2021, 275, 120968. doi: 10.1016/j.biomaterials.2021.120968
  79. Marotta, N. P.; Ara, J.; Uemura, N.; Lougee, M. G.; Meymand, E. S.; Zhang, B.; Petersson, E. J.; Trojanowski, J. Q.; Lee, V. M.-Y. Alpha-Synuclein from Patient Lewy Bodies Exhibits Distinct Pathological Activity That Can Be Propagated in Vitro. Acta Neuropathologica Communications, 2021, 9(1), 188. doi: 10.1186/s40478-021-01288-2
  80. Kohli, J.; Wang, B.; Brandenburg, S. M.; Basisty, N.; Evangelou, K.; Varela-Eirin, M.; Campisi, J.; Schilling, B.; Gorgoulis, V.; Demaria, M. Algorithmic Assessment of Cellular Senescence in Experimental and Clinical Specimens. Nat Protoc, 2021, 16(5), 2471–2498. doi: 10.1038/s41596-021-00505-5
  81. Long, M.; Liu, X.; Huang, X.; Lu, M.; Wu, X.; Weng, L.; Chen, Q.; Wang, X.; Zhu, L.; Chen, Z. Alendronate-Functionalized Hypoxia-Responsive Polymeric Micelles for Targeted Therapy of Bone Metastatic Prostate Cancer. Journal of Controlled Release, 2021, 334, 303–317. doi: 10.1016/j.jconrel.2021.04.035
  82. Moore, C.; Borum, R. M.; Mantri, Y.; Xu, M.; Fajtová, P.; O’Donoghue, A. J.; Jokerst, J. V. Activatable Carbocyanine Dimers for Photoacoustic and Fluorescent Detection of Protease Activity. ACS Sens., 2021, 6(6), 2356–2365. doi: 10.1021/acssensors.1c00518
  83. Valero, J.; Civit, L.; Dupont, D. M.; Selnihhin, D.; Reinert, L. S.; Idorn, M.; Israels, B. A.; Bednarz, A. M.; Bus, C.; Asbach, B.; Peterhoff, D.; Pedersen, F. S.; Birkedal, V.; Wagner, R.; Paludan, S. R.; Kjems, J. A Serum-Stable RNA Aptamer Specific for SARS-CoV-2 Neutralizes Viral Entry. Proc. Natl. Acad. Sci. U.S.A., 2021, 118(50), e2112942118. doi: 10.1073/pnas.2112942118
  84. Dai, C.; Reyes-Ordoñez, A.; You, J.-S.; Chen, J. A Non-Translational Role of Threonyl-TRNA Synthetase in Regulating JNK Signaling during Myogenic Differentiation. The FASEB Journal, 2021, 35(10), e21948. doi: 10.1096/fj.202101094R
  85. Helal, D. O.; Rouatbi, N.; Han, S.; Tzu-Wen Wang, J.; Walters, A. A.; Abdel-Mottaleb, M. M. A.; Kamel, A. O.; Geneidi, A.-S.; Awad, G. A. S.; Al-Jamal, K. T. A Natural Protein Based Platform for the Delivery of Temozolomide Acid to Glioma Cells. European Journal of Pharmaceutics and Biopharmaceutics, 2021, 169, 297–308. doi: 10.1016/j.ejpb.2021.10.007
  86. Taira, Y.; Shimoji, Y.; Nakasone, T.; Arakaki, Y.; Nakamoto, T.; Kinjo, T.; Kudaka, W.; Mekaru, K.; Aoki, Y. A High-Risk Gestational Trophoblastic Neoplasia Derived from a Complete Hydatidiform Mole with Coexisting Fetus Identified by Short Tandem Repeats Analysis: A Case Report. Case Reports in Women’s Health, 2021, 31, e00336. doi: 10.1016/j.crwh.2021.e00336
  87. Ye, Z.; Zhang, Y.; Liu, Y.; Liu, Y.; Tu, J.; Shen, Y. EGFR Targeted Cetuximab-Valine-Citrulline (vc)-Doxorubicin Immunoconjugates- Loaded Bovine Serum Albumin (BSA) Nanoparticles for Colorectal Tumor Therapy. IJN, 2021, 16, 2443–2459. doi: 10.2147/IJN.S289228
  88. Tan, R.; Tian, D.; Liu, J.; Wang, C.; Wan, Y. Doxorubicin-Bound Hydroxyethyl Starch Conjugate Nanoparticles with PH/Redox Responsive Linkage for Enhancing Antitumor Therapy. IJN, 2021, 16, 4527–4544. doi: 10.2147/IJN.S314705
  89. Sivkina, A. L.; Feofanov, A. V.; Kirpichnikov, M. P.; Akhtar, M. S.; Studitsky, V. M. Role of the Nhp6 Protein in Nucleosome Unfolding by the FACT Factor. Moscow Univ. Biol.Sci. Bull., 2021, 76(4), 191–195. doi: 10.3103/S009639252104012X
  90. McCandless, K.; Mishra, S.; Stiltner, J.; Feldman, K. S.; Yagi, H.; Yurko, R.; Islam, K.; Brown, J. M.; Frizzell, R.; Zahid, M. Novel Lung Targeting Cell Penetrating Peptides as Vectors for Delivery of Therapeutics. Research Square, 2021, preprint. doi: 10.21203/rs.3.rs-1056707/v1
  91. Zahid, M.; McCandless, K.; Mishra, S.; Stiltner, J.; Feldman, K.; Yagi, H.; Yurko, R.; Islam, K.; Brown, J.; Frizzell, R. Novel Lung Targeting Cell Penetrating Peptides as Vectors for Delivery of Therapeutics. Research Square, 2021, preprint. doi: 10.21203/rs.3.rs-1056707/v1
  92. Zanon, P.R.A.; Yu, F.; Musacchio, P.; Lewald, L.; Zollo, M.; Krauskopf, K.; Mrdović, D.; Raunft, P.; Maher, T.E.; Cigler, M.; Chang, C.; Lang, K.; Toste, F.D.; Nesvizhskii, A.I.; Hacker, S.M. Profiling the proteome-wide selectivity of diverse electrophiles. ChemRxiv, 2021, preprint. doi: 10.33774/chemrxiv-2021-w7rss-v2
  93. Baker, Y. R.; Yuan, L.; Chen, J.; Belle, R.; Carlisle, R.; El-Sagheer, A. H.; Brown, T. Expanding the Chemical Functionality of DNA Nanomaterials Generated by Rolling Circle Amplification. Nucleic Acids Research, 2021, 49(16), 9042–9052. doi: 10.1093/nar/gkab720
  94. Yang, M.; Sun, R.; Deng, P.; Yang, Y.; Wang, W.; Liu, J.-J. G.; Chen, C. Nonspecific Interactions between SpCas9 and DsDNA Sites Located Downstream of the PAM Mediate Facilitated Diffusion to Accelerate Target Search. Chem. Sci, 2021, 12(38), 12776–12784. doi: 10.1039/D1SC02633J
  95. Si, Y.; Kim, S.; Ou, J.; Lu, Y.; Ernst, P.; Chen, K.; Whitt, J.; Carter, A. M.; Markert, J. M.; Bibb, J. A.; Chen, H.; Zhou, L.; Jaskula-Sztul, R.; Liu, X. Anti-SSTR2 Antibody-Drug Conjugate for Neuroendocrine Tumor Therapy. Cancer Gene Ther, 2021, 28(7–8), 799–812. doi: 10.1038/s41417-020-0196-5
  96. Sasaki, K.; Harada, M.; Yoshikawa, T.; Tagawa, H.; Harada, Y.; Yonemitsu, Y.; Ryujin, T.; Kishimura, A.; Mori, T.; Katayama, Y. Fc-Binding Antibody-Recruiting Molecules Targeting Prostate-Specific Membrane Antigen: Defucosylation of Antibody for Efficacy Improvement. ChemBioChem, 2021, 22(3), 496–500. doi: 10.1002/cbic.202000577
  97. Pishesha, N.; Harmand, T.; Smeding, L. Y.; Ma, W.; Ludwig, L. S.; Janssen, R.; Islam, A.; Xie, Y. J.; Fang, T.; McCaul, N.; Pinney, W.; Sugito, H. R.; Rossotti, M. A.; Gonzalez-Sapienza, G.; Ploegh, H. L. Induction of Antigen-Specific Tolerance by Nanobody–Antigen Adducts That Target Class-II Major Histocompatibility Complexes. Nature Biomedical Engineering, 2021, 5(11), 1389–1401. doi: 10.1038/s41551-021-00738-5
  98. Yu, J.-H.; Steinberg, I.; Davis, R.M.; Malkovskiy, A.V.; Zlitni, A.; Radzyminski, R.K.; Jung, K.O.; Chung, D.T.; Curet, L.D.; D'Souza, A.L.; Chang, E.; Rosenberg, J.; Campbell, J.; Frostig, H.; Park, S.M.; Pratx, G.; Levin, C.; Gambhir, S.S. Noninvasive and Highly Multiplexed Five-Color Tumor Imaging of Near-Infrared Resonant Surface-Enhanced Raman Nanoparticles In Vivo. ACS Nano, 2021, 15(12), 19956-19969. doi: 10.1021/acsnano.1c07470
  99. Carter, J.G.; Iturbe, L.O.; Duprey, J.-L.H.A.; Carter, I.R.; Southern, C.D.; Rana, M.; Whalley, C.M.; Bosworth, A.; Beggs, A.D.; Hicks, M.R.; Tucker, J.H.R.; Dafforn, T.R. Ultrarapid detection of SARS-CoV-2 RNA using a reverse transcription-free exponential amplification reaction, RTF-EXPAR. Proceedings of the National Academy of Sciences, 2021, 118(35), e2100347118. doi: 10.1073/pnas.2100347118
  100. Koide, H.; Okishima, A.; Hoshino, Y.; Kamon, Y.; Yoshimatsu, K.; Saito, K.; Yamauchi, I.; Ariizumi, S.; Zhou, Y.; Xiao, T.-H.; Goda, K.; Oku, N.; Asai, T.; Shea, K. Synthetic hydrogel nanoparticles for sepsis therapy. Nature Communications, 2021, 12(1), 5552. doi: 10.1038/s41467-021-25847-2
  101. Rudack, T.; Teuber, C.; Scherlo, M.; Güldenhaupt, J.; Schartner, J.; Lübben, M.; Klare, J.P.; Gerwert, K.; Kötting, C. The Ras Dimer Structure. Chemical Science, 2021, 12(23), 8178-8189. doi: 10.1039/d1sc00957e
  102. Song, S.; Mason, A.; Post, R.; de Corato, M.; Mestre, R.; Yewdall, A.; Cao, S.; van der Hofstad, R.; Sanchez, S.; Abdelmohsen, L.; van Hest, J.C. Engineering transient dynamics of artificial cells by stochastic distribution of enzymes. Nature Communications, 2021, 12(1), 6897. doi: 10.1038/s41467-021-27229-0
  103. Guarin, M.; Faelens, R.; Giusti, A.; De Croze, N.; Léonard, M.; Cabooter, D.; Annaert, P.; de Witte, P.; Ny, A. Spatiotemporal Imaging and Pharmacokinetic of Fluorescent Compounds in Zebrafish Eleuthero-Embryos After Different Routes of Administration. Scientific Reports, 2021, 11(1), 12229. doi: 10.1038/s41598-021-91612-6.
  104. Wells, C.I.; Al-Ali, H.; Andrews, D.M.; Asquith, C.R.M.; Axtman, A.D.; Chung, M.; Dikic, I.; Ebner, D.; Elkins, J.M.; Ettmayer, P.; Fischer, C.; Frederiksen, M.; Gray, N.S.; Hatch, S.; Knapp, S.; Lee, S.; Lücking, U.; Michaelides, M.; Mills, C.E.; Müller, S.; Owen, D.; Picado, A.; Ramadan, K.; Saikatendu, K.S.; Schröder, M.; Stolz, A.; Tellechea, M.; Treiber, D.K.; Turunen, B.J.; Vilar, S.; Wang, J.; Zuercher, W.J.; Willson, T.M.; Drewry, D.H. The Kinase Chemogenomic Set (KCGS): An open science resource for kinase vulnerability identification. International Journal of Molecular Sciences, 2021, 22(2), 566. doi: 10.3390/ijms22020566
  105. Zakharenkova, S.A.; Katkova, E.A.; Doroshenko, I.A.; Kriveleva, A.S.; Lebedeva, A.N.; Vidinchuk, T.A.; Shik, A.V.; Abramchuk, S.S.; Podrugina, T.A.; Beklemishev, M.K. Aggregation- based fluorescence amplification strategy: "turn-on" sensing of aminoglycosides using near-IR carbocyanine dyes and pre-micellar surfactants. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2021, 247, 119109. doi: 10.1016/j.saa.2020.119109
  106. Petrunina, N.A.; Lebedev, V.V.; Kirillova, Y.G.; Aralov, A..V.; Varizhuk, A.M.; Sardushkin, M.V. DNA Intercalated Motifs with Non-Nucleoside Inserts. Russian Journal of Bioorganic Chemistry, 2021, 47(6), 1341–1344. doi: 10.1134/S1068162021060212
  107. Stepanova, I.A.; Lebedeva, A.N.; Shik, A..V.; Skorobogatov, E.V.; Beklemishev, M.K. Recognition and Determination of Sulfonamides by Near-IR Fluorimetry Using Their Effect on the Rate of the Catalytic Oxidation of a Carbocyanine Dye by Hydrogen Peroxide. Journal of Analytical Chemistry, 2021, 76(12), 1399–1407. doi: 10.1134/S1061934821120121
  108. Huang, S.-K.; Whitney, P.H.; Dutta, S.; Shvartsman, S.Y.; Rushlow, C.A. Spatial organization of transcribing loci during early genome activation in Drosophila. Current Biology, 2021, 31(22), 5102–5110. doi: 10.1016/j.cub.2021.09.027
  109. do Valle Gomes, M.Z.; Masdeu, G.; Eiring, P.; Kuhlemann, A.; Sauer, M.; Åkerman, B:; Palmqvist, A.E.C. Improved biocatalytic cascade conversion of CO2 to methanol by enzymes Co-immobilized in tailored siliceous mesostructured cellular foams. Catalysis Science & Technology, 2021, 11(21), 6952–6959. doi: 10.1039/D1CY01354H
  110. Lee, R.; Erstling, J.A.; Hinckley, J.A.; Chapman, D.V.; Wiesner, U.B. Addressing Particle Compositional Heterogeneities in Super-Resolution-Enhanced Live-Cell Ratiometric pH Sensing with Ultrasmall Fluorescent Core–Shell Aluminosilicate Nanoparticles. Advanced Functional Materials, 2021, 31(45), 2106144. doi: 10.1002/adfm.202106144
  111. Mu, Q.; Lin, G.; Jeon, M.; Wang, H.; Chang, F.-C.; Revia, R.A.; Yu, J.; Zhang, M. Iron oxide nanoparticle targeted chemo-immunotherapy for triple negative breast cancer. Materials Today, 2021, 50, 149–169. doi: 10.1016/j.mattod.2021.08.002
  112. Abbasov, M.E.; Kavanagh, M.E.; Ichu, T.-A.; Lazear, M.R.; Tao, Y.; Crowley, V.M.; am Ende, C.W.; Hacker, S.M.; Ho, J.; Dix, M.M.; Suciu, R.; Hayward, M.M.; Kiessling, L.L.; Cravatt, B.F. A proteome-wide atlas of lysine-reactive chemistry. Nature Chemistry, 2021, 13(11), 1081–1092. doi: 10.1038/s41557-021-00765-4
  113. Lee, J.-R.; Park, B.-W.; Park, J.-H.; Lim, S.; Kwon, S.P.; Hwang, J.-W.; Kim, H.; Park, H.-J.; Kim, B.-S. Local delivery of a senolytic drug in ischemia and reperfusion-injured heart attenuates cardiac remodeling and restores impaired cardiac function. Acta Biomaterialia, 2021, 135, 520--533. doi: 10.1016/j.actbio.2021.08.028
  114. Igarashi, K.; Cabral, H.; Hong, T.; Anraku, Y.; Mpekris, F.; Stylianopoulos, T.; Khan, T.; Matsumoto, A.; Kataoka, K.; Matsumoto, Y.; Yamasoba, T. Vascular Bursts Act as a Versatile Tumor Vessel Permeation Route for Blood-Borne Particles and Cells. Small, 2021, 17(42), 2103751. doi: 10.1002/smll.202103751
  115. Nkanga, C.I.; Chung, Y.H.; Shukla, S.; Zhou, J.; Jokerst, J.V.; Steinmetz, N.F. The in vivo fate of tobacco mosaic virus nanoparticle theranostic agents modified by the addition of a polydopamine coat. Biomaterials Science, 2021, 9(21), 7134–7150. doi: 10.1039/D1BM01113H
  116. Schmidt, V.; Horváth, C.; Dong, H.; Blüher, M.; Qvist, P.; Wolfrum, C.; Willnow, T.E. SORLA is required for insulin-induced expansion of the adipocyte precursor pool in visceral fat. Journal of Cell Biology, 2021, 220(12), e202006058. doi: 10.1083/jcb.202006058
  117. Lobov, A.A.; Babkina, I.Y.; Danilov, L.G.; Masharskiy, A.E.; Predeus, A.V.; Mikhailova, N.A.; Granovitch, A.I.; Maltseva, A.L. Species-Specific Proteins in the Oviducts of Snail Sibling Species: Proteotranscriptomic Study of Littorina fabalis and L. obtusata. Biology, 2021, 10(11), 1087. doi: 10.3390/biology10111087
  118. Francis, D.M. Manspeaker, M.P.; Archer, P.A.; Sestito, L.F.; Heiler, A.J.; Schudel, A.; Thomas, S.N. Drug-eluting immune checkpoint blockade antibody-nanoparticle conjugate enhances locoregional and systemic combination cancer immunotherapy through T lymphocyte targeting. Biomaterials, 2021, 279, 121184. doi: 10.1016/j.biomaterials.2021.121184
  119. Nascimento, A.; Pedro, M.N.S.; Pinto, I.F.; Aires-Barros, M.R.; Azevedo, A.M. Microfluidics as a high-throughput solution for chromatographic process development – The complexity of multimodal chromatography used as a proof of concept. Journal of Chromatography A, 2021, 1658, 462618. doi: 10.1016/j.chroma.2021.462618
  120. Bauer, B.W.; Davidson, I.F.; Canena, D.; Wutz, G.; Tang, W.; Litos, G.; Horn, S.; Hinterdorfer, P.; Peters, J.-M. Cohesin mediates DNA loop extrusion by a “swing and clamp” mechanism. Cell, 2021, 184(21), 5448--5464.e22. doi: 10.1016/j.cell.2021.09.016
  121. Kong, S.M.; Costa, D.F.; Jagielska, A.; Van Vliet, K.J.; Hammond, P.T. Stiffness of targeted layer-by-layer nanoparticles impacts elimination half-life, tumor accumulation, and tumor penetration. Proceedings of the National Academy of Sciences, 2021, 118(42), e2104826118. doi: 10.1073/pnas.2104826118
  122. Nobori, T.; Kishimura, A.; Mori, T.; Katayama, Y. A FRET-based Protein Kinase Assay using Phos-tag-modified Quantum Dots and Fluorophore-labeled Peptides. Analytical Sciences, 2021, 37(10), 1361–1366. doi: 10.2116/analsci.20P443
  123. van Beek, L.F.; Welzen, P.L.W.; Teufel, L.U.; Joosten, I.; Diavatopoulos, D.A.; van Hest, J.; de Jonge, M.I. Bimodal Targeting of Human Leukocytes by Fc- and CpG-Decorated Polymersomes to Tune Immune Induction. Biomacromolecules, 2021, 22(10), 4422–4433. doi: 10.1021/acs.biomac.1c00985
  124. Li, D.; Taylor, D.H.; van Wolfswinkel, J.C. PIWI-mediated control of tissue-specific transposons is essential for somatic cell differentiation. Cell Reports, 2021, 37(1), 109776. doi: 10.1016/j.celrep.2021.109776
  125. Liu, Q.; Tian, J.; Liu, J.; Zhu, M.; Gao, Z.; Hu, X.; Midgley, A.C.; Wu, J.; Wang, Xi.; Kong, D.; Zhuang, J.; Liu, J.; Yan, X.; Huang, X. Modular Assembly of Tumor-Penetrating and Oligomeric Nanozyme Based on Intrinsically Self-Assembling Protein Nanocages. Advanced Materials, 2021, 33(39), 2103128. doi: 10.1002/adma.202103128
  126. Umebara, M.; Sugai, N.; Murayama, K.; Sugawara, T.; Akashi, Y.; Morita, Y.; Kato, R.; Komatsu, T. Catalase-driven protein microtube motors with different exterior surfaces as ultrasmall biotools. Materials Advances, 2021, 2(19), 6428–6438. doi: 10.1039/D1MA00610J
  127. Yang, X.; Xia, X.; Xia, X.-X.; Sun, Z.; Yan, D. Improving Targeted Delivery and Antitumor Efficacy with Engineered Tumor Necrosis Factor-Related Apoptosis Ligand-Affibody Fusion Protein. Molecular Pharmaceutics, 2021, 18(10), 3854–3861. doi: 10.1021/acs.molpharmaceut.1c00483
  128. Özcan, A.; Krajeski, R.; Ioannidi, E.; Lee, B.; Gardner, A.; Makarova, K.S.; Koonin, E.V.; Abudayyeh, O.O.; Gootenberg, J.S. Programmable RNA targeting with the single-protein CRISPR effector Cas7-11. Nature, 2021, 597(7878), 720–725. doi: 10.1038/s41586-021-03886-5
  129. Wang, Q.; Gao, Z.; Zhong, Q.-Z.; Wang, N.; Mei, H.; Dai, Q.; Cui, J.; Hao, J. Encapsulation of Enzymes in Metal{\textendash}Phenolic Network Capsules for the Trigger of Intracellular Cascade Reactions. Langmuir, 2021, 37(38), 11292–11300. doi: 10.1021/acs.langmuir.1c01821
  130. Puthenveetil, R.; Lun, C.M.; Murphy, R.E.; Healy, L.B.; Vilmen, G.; Christenson, E.T.; Freed, E.O.; Banerjee, A. S-acylation of SARS-CoV-2 Spike Protein: Mechanistic Dissection, In Vitro Reconstitution and Role in Viral Infectivity. Journal of Biological Chemistry, 2021, 297(4), 101112. doi: 10.1016/j.jbc.2021.101112
  131. Dao, N.V.; Ercole, F.; Li, Y.; Davis, T.P.; Kaminskas, L.M.; Sloan, E.K.; Quinn, J.F.; Whittaker, M.R. Nitroxide-functional PEGylated nanostars arrest cellular oxidative stress and exhibit preferential accumulation in co-cultured breast cancer cells. Journal of Materials Chemistry B, 2021, 9(37), 7805–7820. doi: 10.1039/D1TB00812A
  132. Baranova, M.N.; Babikova, P.A.; Kudzhaev, A.M.; Mokrushina, Y.A.; Belozerova, O.A.; Yunin, M.A.; Kovalchuk, S.; Gabibov, A.G.; Smirnov, I.V.; Terekhov, S.S. Live Biosensors for Ultrahigh-Throughput Screening of Antimicrobial Activity against Gram-Negative Bacteria. Antibiotics, 2021, 10(10), 1161. doi: 10.3390/antibiotics10101161
  133. Morozov, V.N.; Klimovich, M.A.; Kolyvanova, M.A.; Dement'eva, O.V.; Rudoy, V.M.; Kuzmin, V.A. Interaction of Gold Nanoparticles with Cyanine Dyes in Cholesteric DNA Submicroparticles. High Energy Chemistry, 2021, 55(5), 341–348. doi: 10.1134/S0018143921050088
  134. Wang, S.; Latallo, M.J.; Zhang, Z.; Huang, B.; Bobrovnikov, D.G.; Dong, D.; Livingston, N.M.; Tjoeng, W.; Hayes, L.R.; Rothstein, J.D.; Ostrow, L.W.; Wu, B.; Sun, S. Nuclear export and translation of circular repeat-containing intronic RNA in C9ORF72-ALS/FTD. Nature Communications, 2021, 12(1), 4908. doi: 10.1038/s41467-021-25082-9
  135. Woodford, M.R.; Baker-Williams, A.J.; Sager, R.A.; Backe, S.J.; Blanden, A.R.; Hashmi, F.; Kancherla, P.; Gori, A.; Loiselle, D.R.; Castelli, M.; Serapian, S.A.; Colombo, G.; Haystead, T.A.; Jensen, S.M.; Stetler-Stevenson, W.G.; Loh, S.N.; Schmidt, L.S.; Linehan, W.M.; Bah, A.; Bourboulia, D.; Bratslavsky, G.; Mollapour, M. The tumor suppressor folliculin inhibits lactate dehydrogenase A and regulates the Warburg effect. Nature Structural & Molecular Biology, 2021, 28(8), 662–670. doi: 10.1038/s41594-021-00633-2
  136. Guo, H.; Liu, L.; Hu, Q.; Dou, H. Mixed Solvent Method for Improving the Size Uniformity and Cargo-Loading Efficiency of ZIF-8 Nanoparticles. Langmuir, 2021, 37(33), 10089–10099. doi: 10.1021/acs.langmuir.1c01399
  137. Lo, Y.-C.; Lin, W.-J. Benefit of a Short Chain Peptide as a Targeting Ligand of Nanocarriers for a Brain-Driven Purpose. Pharmaceutics, 2021, 13(8), 1249. doi: 10.3390/pharmaceutics13081249
  138. Saifutiarova, A.E.; Fedorov, Y.V.; Tsvetkov, V.B.; Rustamova, D.A.; Gulakova, E.N.; Chmelyuk, N.S.; Abakumov, M.A.; Aliev, T.M.; Fedorova, O.A. Photochemical synthesis, intercalation with DNA and antitumor evaluation in vitro of benzo[d]thiazolo[3,2-a]quinolin-10-ium derivatives. Bioorganic Chemistry, 2021, 115, 105267. doi: 10.1016/j.bioorg.2021.105267
  139. Carter, J.G.; Iturbe, L.O.; Duprey, J.-L.H.A.; Carter, I.R.; Southern, C.D.; Rana, M.; Whalley, C.M.; Bosworth, A.; Beggs, A.D.; Hicks, M.R.; Tucker, J.H.R.; Dafforn, T.R. Ultrarapid detection of SARS-CoV-2 RNA using a reverse transcription{\textendash}free exponential amplification reaction, RTF-EXPAR. Proceedings of the National Academy of Sciences of the U.S.A., 2021, 118(35), e2100347118. doi: 10.1073/pnas.2100347118
  140. Tamarov, K.; Wang, J.T.W.; Kari, J.; Happonen, E.; Vesavaara, I.; Niemelä, M.; Perämäki, P.; Al-Jamal, K.T.; Xu, W.; Lehto, V.-P. Comparison between Fluorescence Imaging and Elemental Analysis to Determine Biodistribution of Inorganic Nanoparticles with Strong Light Absorption. ACS Applied Materials & Interfaces, 2021, 13(34), 40392–40400. doi: 10.1021/acsami.1c11875
  141. Koide, H.; Okishima, A.; Hoshino, Y.; Kamon, Y.; Yoshimatsu, K.; Saito, K.; Yamauchi, I.; Ariizumi, S.; Zhou, Y.; Xiao, T.-H.; Goda, K.; Oku, N.; Asai, T.; Shea, K.J. Synthetic hydrogel nanoparticles for sepsis therapy. Nature Communications, 2021, 12(1), 5552. doi: 10.1038/s41467-021-25847-2
  142. Koch, P.D.; Quintana, J.; Ahmed, M.S.; Kohler, R.H.; Weissleder, R. Small Molecule Imaging Agent for Mutant KRAS G12C. Advanced Therapeutics, 2021, 4(5), 2000290. doi: 10.1002/adtp.202000290
  143. Kamzabek, D.; Le Dé, B.; Coche-Guérente, L.; Miomandre, F.; Dubacheva, G.V. Thermoresponsive Fluorescence Switches Based on Au@pNIPAM Nanoparticles. Langmuir, 2021, 37(37), 10971–10978. doi: 10.1021/acs.langmuir.1c01397
  144. Hong, T.; Miyazaki, T.; Matsumoto, A.; Koji, K.; Miyahara, Y.; Anraku, Y.; Cabral, H. Phosphorylcholine-Installed Nanocarriers Target Pancreatic Cancer Cells through the Phospholipid Transfer Protein. ACS Biomaterials Science & Engineering, 2021, 7(9), 4439–4445. doi: 10.1021/acsbiomaterials.1c00730
  145. Yu, S.; Yang, H.; Li, T.; Pan, H.; Ren, S.; Luo, G.; Jiang, J.; Yu, L.; Chen, B.; Zhang, Y.; Wang, S.; Tian, R.; Zhang, T.; Zhang, S.; Chen, Y.; Yuan, Q.; Ge, S.; Zhang, J.; Xia, N. Efficient intracellular delivery of proteins by a multifunctional chimaeric peptide in vitro and in vivo. Nature Communications, 2021, 12(1), 5131. doi: 10.1038/s41467-021-25448-z
  146. Song, J.W.; Nam, H.S.; Ahn, J.W.; Park, H.-S.; Kang, D.O.; Kim, H.J.; Kim, Y.H.; Han, J.; Choi, J.Y.; Lee, S.-Y.; Kim, S.; Oh, W.-Y.; Yoo, H.; Park, K.; Kim, J.W. Macrophage targeted theranostic strategy for accurate detection and rapid stabilization of the inflamed high-risk plaque. Theranostics, 2021, 11(18), 8874–8893. doi: 10.7150/thno.59759
  147. Hurley, C.M.; Kraut, D.A. Determination of Proteasomal Unfolding Ability. Methods in Molecular Biology, 2021, 2365, 217–244. doi: 10.1007/978-1-0716-1665-9_12
  148. Wiktor, J.; Gynnå, A.H.; Leroy, P.; Larsson, J.; Coceano, G.; Testa, I.; Elf, J. RecA finds homologous DNA by reduced dimensionality search. Nature, 2021, 597(7876), 426–429. doi: 10.1038/s41586-021-03877-6
  149. Svetlova, J.; Sardushkin, M.; Kolganova, N.; Timofeev, E. Recognition Interface of the Thrombin Binding Aptamer Requires Antiparallel Topology of the Quadruplex Core. Biomolecules, 2021, 11(9), 1332. doi: 10.3390/biom11091332
  150. Demin, A.M.; Pershina, A.G.; Minin, A.S.; Brikunova, O.Y.; Murzakaev, A.M.; Perekucha, N.A.; Romashchenko, A.V.; Shevelev, O.B.; Uimin, M.A.; Byzov, I.V.; Malkeyeva, D.; Kiseleva, E.; Efimova, L.V.; Vtorushin, S.V.; Ogorodova, L.M.; Krasnov, V.P. Smart Design of a pH-Responsive System Based on pHLIP-Modified Magnetite Nanoparticles for Tumor MRI. ACS Applied Materials & Interfaces, 2021, 13(31), 36800–36815. doi: 10.1021/acsami.1c07748
  151. Rosier, N.; Grätz, L.; Schihada, H.; Möller, J.; Işbilir, A.; Humphrys, L.J.; Nagl, M.; Seibel, U.; Lohse, M.J.; Pockes, S. A Versatile Sub-Nanomolar Fluorescent Ligand Enables NanoBRET Binding Studies and Single-Molecule Microscopy at the Histamine H3 Receptor. Journal of Medicinal Chemistry, 2021, 64(15), 11695–11708. doi: 10.1021/acs.jmedchem.1c01089
  152. Zhuo, X.-Z.; Bai, K.; Wang, Y.; Liu, P.; Xi, W.; She, J.; Liu, J. Long-chain non-coding RNA-GAS5 / hsa-miR-138-5p attenuates high glucose-induced cardiomyocyte damage by targeting CYP11B2. Bioscience Reports, 2021, 41(9), BSR20202232. doi: 10.1042/BSR20202232
  153. Son, S.; Shin, J.M.; Shin, S.; Kim, C.H.; Lee, J.A.; Ko, H.; Lee, E.S.; Jung, J.M:; Kim, J.; Park, J.H. Repurposing macitentan with nanoparticle modulates tumor microenvironment to potentiate immune checkpoint blockade. Biomaterials, 2021, 276, 121058. doi: 10.1016/j.biomaterials.2021.121058
  154. Buehler, P.W.; Swindle, D.; Pak, D.I.; Ferguson, S.K.; Majka, S.M.; Karoor, V.; Moldovan, R.; Sintas, C.; Black, J.; Gentinetta, T.; Buzzi, R.M.; Vallelian, F.; Wassmer, A.; Edler, M.; Bain, J.; Schu, D.; Hassell, K.; Nuss, R.; Schaer, D.J.; Irwin, D.C. Hemopexin dosing improves cardiopulmonary dysfunction in murine sickle cell disease. Free Radical Biology and Medicine, 2021, 175, 95–107. doi: 10.1016/j.freeradbiomed.2021.08.238
  155. Eliseev, I.E.; Ukrainskaya, V.M.; Yudenko, A.N.; Mikushina, A.D.; Shmakov, S.V.; Afremova, A.I.; Ekimova, V.M.; Vronskaia, A.A.; Knyazev, N.A.; Shamova, O.V. Targeting ErbB3 Receptor in Cancer with Inhibitory Antibodies from Llama. Biomedicines, 2021, 9(9), 1106. doi: 10.3390/biomedicines9091106
  156. Pham, L.M.; Poudel, K.; Phung, C.D.; Nguyen, T.T.; Pandit, M.; Nguyen, H.T.; Chang, J.-H.; Jin, S.G.; Jeong, J.-H.; Ku, S.K.; Choi, H.-G.; Yong, C.S.; Kim, J.O. Preparation and evaluation of dabrafenib-loaded, CD47-conjugated human serum albumin-based nanoconstructs for chemoimmunomodulation. Colloids and Surfaces B: Biointerfaces, 2021, 208, 112093. doi: 10.1016/j.colsurfb.2021.112093
  157. Charoen-Rajapark, P.; Clarke, D.R. Confocal microscopy observations of electrical pre-breakdown of bi-layer elastomer dielectrics. Extreme Mechanics Letters, 2021, 49, 101473. doi: 10.1016/j.eml.2021.101473
  158. Nosella, M.L.; Tereshchenko, M.; Pritišanac, I.; Chong, P.A.; Toretsky, J.A.; Lee, H.O.; Forman-Kay, J.D. O-Linked-N-Acetylglucosaminylation of the RNA-Binding Protein EWS N-Terminal Low Complexity Region Reduces Phase Separation and Enhances Condensate Dynamics. Journal of the American Chemical Society, 2021, 143(30), 11520–11534. doi: 10.1021/jacs.1c04194
  159. Yamansarov, E.Y.; Lopatukhina, E.V.; Evteev, S.A.; Skvortsov, D.A.; Lopukhov, A.V.; Kovalev, S.V.; Vaneev, A.N.; Shkil', D.O.; Akasov, R.A.; Lobov, A,.N.; Naumenko, V.A.; Pavlova, E.N.; Ryabaya, O.O.; Burenina, O.Y.; Ivanenkov, Y.A.; Klyachko, N.L.; Erofeev, A.S.; Gorelkin, P.V.; Beloglazkina, E.K.; Majouga, A. Discovery of Bivalent GalNAc-Conjugated Betulin as a Potent ASGPR-Directed Agent against Hepatocellular Carcinoma. Bioconjugate Chemistry, 2021, 32(4), 763–781. doi: 10.1021/acs.bioconjchem.1c00042
  160. Tao, Y.; Xie, J.; Zhong, Q.; Wang, Y.; Zhang, S.; Luo, F.; Wen, F.; Xie, J.; Zhao, J.; Sun, X.; Long, H.; Ma, J.; Zhang, Q.; Long, J.; Fang, X.; Lu, Y.; Li, D.; Li, M.; Zhu, J.; Sun, B.; Li, G.; Diao, J.; Liu, C. A novel partially open state of {SHP}2 points to a "multiple gear" regulation mechanism. Journal of Biological Chemistry, 2021, 296, 100538. doi: 10.1016/j.jbc.2021.100538
  161. Kim, H.; Yuk, S.A.; Dieterly, A.M.; Kwon, S.; Park, J.; Meng, F.; Gadalla, H.H.; Cadena, M.J.; Lyle, L.T.; Yeo, Y. Nanosac, a Noncationic and Soft Polyphenol Nanocapsule, Enables Systemic Delivery of siRNA to Solid Tumors. ACS Nano, 2021, 15(3), 4576–4593. doi: 10.1021/acsnano.0c08694
  162. Bagert, J.D.; Mitchener, M.M.; Patriotis, A.L.; Dul, B.E.; Wojcik, F.; Nacev, B.A.; Feng, L.; Allis, C.D.; Muir, T.W. Oncohistone mutations enhance chromatin remodeling and alter cell fates. Nature Chemical Biology, 2021, 17(4), 403–411. doi: 10.1038/s41589-021-00738-1
  163. Nong, J.; Kang, K.; Shi, Q.; Zhu, X.; Tao, Q.; Chen, Y.-G. Phase separation of Axin organizes the β-catenin destruction complex. Journal of Cell Biology, 2021, 220(4), 202012112. doi: 10.1083/jcb.202012112
  164. Barrios-Hernández, M.L.; Bettinelli, C.; Mora-Cabrera, K.; Vanegas-Camero, M.-C.; Garcia, H.; van de Vossenberg, J.; Prats, D.; Brdjanovic, D.; van Loosdrecht, M.C.M.; Hooijmans, C.M. Unravelling the removal mechanisms of bacterial and viral surrogates in aerobic granular sludge systems. Water Research, 2021, 195, 116992. doi: 10.1016/j.watres.2021.116992
  165. Radzisheuskaya, A.; Shliaha, P.V.; Grinev, V.V.; Shlyueva, D.; Damhofer, H.; Koche, R.; Gorshkov, V.; Kovalchuk, S.; Zhan, Y.; Rodriguez, K.L.; Johnstone, A.L.; Keogh, M.-C.; Hendrickson, R.C.; Jensen, O.N.; Helin, K. Complex-dependent histone acetyltransferase activity of KAT8 determines its role in transcription and cellular homeostasis. Molecular Cell, 2021, 81(8), 1749–1765. doi: 10.1016/j.molcel.2021.02.012
  166. Wang, Y.; Cottle, W.T.; Wang, H.; Feng, X.A.; Mallon, J.; Gavrilov, M.; Bailey, S.; Ha, T. Genome oligopaint via local denaturation fluorescence in situ hybridization. Molecular Cell, 2021, 81(7), 1566–1577. doi: 10.1016/j.molcel.2021.02.011
  167. So, I.-S.; Kang, J.H.; Hong, J.W.; Sung, S.; Hasan, A.F.; Sa, K.H.; Han, S.W.; Kim, I.S.; Kang, Y.M. A novel apoptosis probe, cyclic ApoPep-1, for in vivo imaging with multimodal applications in chronic inflammatory arthritis. Apoptosis, 2021, 26(3–4), 209–218. doi: 10.1007/s10495-021-01659-z
  168. Robla, S.; Prasanna, M.; Varela-Calviño, R.; Grandjean, C.; Csaba, N. A chitosan-based nanosystem as pneumococcal vaccine delivery platform. Drug Delivery and Translational Research, 2021, 11(2), 581–597. doi: 10.1007/s13346-021-00928-3
  169. Sun, X.; Du, J.D.; Hawley, A.; Tan, A.; Boyd, B.J. Magnetically-stimulated transformations in the nanostructure of PEGylated phytantriol-based nanoparticles for on-demand drug release. Colloids and Surfaces B: Biointerfaces, 2021, 207, 112005. doi: 10.1016/j.colsurfb.2021.112005
  170. Zhang, Q.; Agius, S.C.; Flanigan, S.F.; Uckelmann, M.; Levina, V.; Owen, B.M.; Davidovich, C. PALI1 facilitates DNA and nucleosome binding by PRC2 and triggers an allosteric activation of catalysis. Nature Communications, 2021, 12(1), 4592. doi: 10.1038/s41467-021-24866-3
  171. Kántor, I.; Aparaschivei, D.; Todea, A.; Biró, E.; Babos, G.; Szerényi, D.; Kakasi, B.; Péter, F:; Şişu, Eugen and Feczkó, T. Biocatalytic synthesis of poly[ε-caprolactone-co-(12-hydroxystearate)] copolymer for sorafenib nanoformulation useful in drug delivery. Catalysis Today, 2021, 366, 195–201. doi: 10.1016/j.cattod.2020.05.005
  172. Chiou, A.E.; Hinckley, J.A.; Khaitan, R:; Varsano, N.; Wang, J.; Malarkey, H.F.; Hernandez, C.J.; Williams, R.M.; Estroff, L.A.; Weiner, S.; Addadi, L.; Wiesner, U.B.; Fischbach, C. Fluorescent Silica Nanoparticles to Label Metastatic Tumor Cells in Mineralized Bone Microenvironments. Small, 2021, 17(15), 2001432. doi: 10.1002/smll.202001432
  173. Yang, X.; Wang, Z.; Huang, H.; Ling, S.; Zhang, R.; Zhang, Y.; Chen, G.; Li, C.; Wang, Q. A Targeted Activatable NIR-IIb Nanoprobe for Highly Sensitive Detection of Ischemic Stroke in a Photothrombotic Stroke Model. Advanced Healthcare Materials, 2021, 10(5), 2001544. doi: 10.1002/adhm.202001544
  174. Koch, S.; Seinen, A.-B.; Kamel, M.; Kuckla, D.; Monzel, C.; Kedrov, A.; Driessen, A.J.M. Single-molecule analysis of dynamics and interactions: of the SecYEG translocon. FEBS Journal, 2021, 288(7), 2203–2221. doi: 10.1111/febs.15596
  175. Roberts, S.; Khera, E.; Choi, C.; Navaratna, T.; Grimm, J.; Thurber, G.M.; Reiner, T. Optoacoustic imaging of Glucagon-like Peptide 1 Receptor with a near-infrared exendin-4 analog. Journal of Nuclear Medicine, 2021, 62(6), 839–848. doi: 10.2967/jnumed.120.252262
  176. Geng, S.; Li, Z.; Zhang, R.; Zhou, W.; Luo, G.; Chu, P.K.; Yu, X.-F. Complete ablation of resistant tumors with photosensitive black phosphorus quantum dots-based lipid nanocapsules. Chemical Engineering Journal, 2021, 421, 127879. doi: 10.1016/j.cej.2020.127879
  177. Geng, H.; Zhou, M.; Li, B.; Liu, L.; Yang, X.; Wen, Y.; Yu, H.; Wang, H.; Chen, J.; Chen, L. Metal-drug nanoparticles-mediated osteolytic microenvironment regulation for enhanced radiotherapy of orthotopic osteosarcoma. Chemical Engineering Journal, 2021, 417, 128103. doi: 10.1016/j.cej.2020.128103
  178. Xu, C.; Wang, Y.; Wang, E.; Yan, N.; Sheng, S.; Chen, J.; Lin, L.; Guo, Z.; Tian, H.; Chen, X. Effective Eradication of Tumors by Enhancing Photoacoustic-Imaging-Guided Combined Photothermal Therapy and Ultrasonic Therapy. Advanced Functional Materials, 2021, 31(10), 2009314. doi: 10.1002/adfm.202009314
  179. Nie, T.; He, Z.; Zhu, J.; Chen, K.; Howard, G.P.; Pacheco-Torres, J.; Minn, I.; Zhao, P.; Bhujwalla, Z.M.; Mao, H.-Q.; Liu, L.; Chen, Y. Non-invasive delivery of levodopa-loaded nanoparticles to the brain via lymphatic vasculature to enhance treatment of Parkinson's disease. Nano Research, 2021, 14(8), 2749–2761. doi: 10.1007/s12274-020-3280-0
  180. Ahn, Y.J.; Yun, W.S.; Choi, J.S.; Kim, W.C.; Lee, S.H.; Park, D.J.; Park, J.E.; Key, J.; Seo, Y.J. Biodistribution of poly clustered superparamagnetic iron oxide nanoparticle labeled mesenchymal stem cells in aminoglycoside induced ototoxic mouse model. Biomedical Engineering Letters, 2021, 11(1), 39–53. doi: 10.1007/s13534-020-00181-6
  181. Krchlíková, V.; Mikešová, J.; Geryk, J.; Bařinka, C.; Nexo, E.; Fedosov, S.N.; Kosla, J.; Kučerová, D.; Reinišová, M.; Hejnar, J.; Elleder, D. The avian retroviral receptor Tva mediates the uptake of transcobalamin bound vitamin B12 (cobalamin). Journal of Virology, 2021, 95(8). doi: 10.1128/JVI.02136-20
  182. Slor, G.; Olea, A.R.; Pujals, S.; Tigrine, A.; De La Rosa, V.R.; Hoogenboom, R.; Albertazzi, L.; Amir, R.J. Judging Enzyme-Responsive Micelles by Their Covers: Direct Comparison of Dendritic Amphiphiles with Different Hydrophilic Blocks. Biomacromolecules, 2021, 22(3), 1197–1210. doi: 10.1021/acs.biomac.0c01708
  183. Deckard, C.E.; Sczepanski, J.T. Reversible chromatin condensation by the DNA repair and demethylation factor thymine DNA glycosylase. Nucleic Acids Research, 2021, 49(5), 2450–2459. doi: 10.1093/nar/gkab040
  184. Chariou, P.L.; Beiss, V.; Ma, Y.; Steinmetz, N.F. In situ vaccine application of inactivated CPMV nanoparticles for cancer immunotherapy. Materials Advances, 2021, 2(5), 1644–1656. doi: 10.1039/D0MA00752H
  185. Li, S.; Luo, M.; Wang, Z.; Feng, Q.; Wilhelm, J.; Wang, X.; Li, W.; Wang, J.; Cholka, A.; Fu, Y.-X.; Sumer, B.D.; Yu, H.; Gao, J. Prolonged activation of innate immune pathways by a polyvalent STING agonist. Nature Biomedical Engineering, 2021, 5(5), 455–466. doi: 10.1038/s41551-020-00675-9
  186. Ieong, K.-W.; Indrisiunaite, G.; Prabhakar, A.; Puglisi, J.D.; Ehrenberg, M. N6-Methyladenosines in mRNAs reduce the accuracy of codon reading by transfer RNAs and peptide release factors. Nucleic Acids Research, 2021, 49(5), 2684–2699. doi: 10.1093/nar/gkab033
  187. Schotman, M.J.G.; Peters, M.M.C.; Krijger, G.C.; van Adrichem, I.; de Roos, R.; Bemelmans, J.L.M.; Pouderoijen, M.J.; Rutten, M.G.T.A.; Neef, K.; Chamuleau, S.A.J.; Dankers, P.Y.W. In Vivo Retention Quantification of Supramolecular Hydrogels Engineered for Cardiac Delivery. Advanced Healthcare Materials, 2021, 10(10), e2001987. doi: 10.1002/adhm.202001987
  188. Kochappan, R.; Cao, E.; Han, S.; Hu, L.; Quach, T.; Senyschyn, D.; Ferreira, V.I.; Lee, G.; Leong, N.; Sharma, G.; Lim, S.F.; Nowell, C.J.; Chen, Z.; von Andrian, U.H.; Bonner, D.; Mintern, J.D.; Simpson, J.S.; Trevaskis, N.L.; Porter, C.J.H. Targeted delivery of mycophenolic acid to the mesenteric lymph node using a triglyceride mimetic prodrug approach enhances gut-specific immunomodulation in mice. Journal of Controlled Release, 2021, 332, 636–651. doi: 10.1016/j.jconrel.2021.02.008
  189. Deirram, N.; Kermaniyan, S.S.; Johnston, A.P.R.; Such, G.K. Understanding the Polymer Rearrangement of pH-Responsive Nanoparticles. Australian Journal of Chemistry, 2021, 74(7), 514–521. doi: 10.1071/CH20331
  190. Best, Q.A.; Haack, R.A.; Swift, K.M.; Bax, B.M.; Tetin, S.Y.; Hershberger, S.J. A Rainbow of Acridinium Chemiluminescence. Luminescence, 2021, 36(4), 1097–1106. doi: 10.1002/bio.4038
  191. Nixon, B.; Anderson, A.L.; Bromfield, E.G.; Martin, J.H.; Cafe, S.L.; Skerrett-Byrne, D.A.; Dun, M.D.; Eamens, A.L.; De Iuliis, G.N.; Johnston, S.D. Post-testicular sperm maturation in the saltwater crocodile Crocodylus porosus: assessing the temporal acquisition of sperm motility. Reproduction, Fertility, and Development, 2021, 33(9), 530–539. doi: 10.1071/RD20204
  192. Fernández-Rico, C.; Urbach, J.S.; Dullens, R.P.A. Synthesis of Rough Colloidal SU-8 Rods and Bananas via Nanoprecipitation. Langmuir, 2021, 37(9), 2900–2906. doi: 10.1021/acs.langmuir.0c03361
  193. Lu, Z.; Zhang, Y.; Wang, Y.; Tan, G.-H.; Huang, F.-Y.; Cao, R.; He, N.; Zhang, L. A biotin-avidin-system-based virus-mimicking nanovaccine for tumor immunotherapy. Journal of Controlled Release, 2021, 332, 245–259. doi: 10.1016/j.jconrel.2021.02.029
  194. Berditchevskii, G.M.; Vasina, L.V.; Ageev, S.V.; Meshcheriakov, A.A.; Galkin, M.A.; Ishmukhametov, R.R.; Nashchekin, A.V.; Kirilenko, D.A.; Petrov, A.V.; Martynova, S.D.; Semenov, K.N.; Sharoyko, V.V. A comprehensive study of biocompatibility of detonation nanodiamonds. Journal of Molecular Liquids, 2021, 332, 115763. doi: 10.1016/j.molliq.2021.115763
  195. Yamansarov, E.Y.; Lopatukhina, E.V.; Evteev, S.A.; Skvortsov, D.A.; Lopukhov, A.V.; Kovalev, S.V.; Vaneev, A.N.; Shkil', D.O.; Akasov, R.A.; Lobov, A.N.; Naumenko, V.A.; Pavlova, E.N.; Ryabaya, O.O.; Burenina, O.Y.; Ivanenkov, Y.A.; Klyachko, N.L.; Erofeev, A.S.; Gorelkin, P.V.; Beloglazkina, E.K.; Majouga, A.G. Discovery of Bivalent GalNAc-Conjugated Betulin as a Potent ASGPR-Directed Agent against Hepatocellular Carcinoma. Bioconjugate Chemistry, 2021, 32(4), 763–781. doi: 10.1021/acs.bioconjchem.1c00042
  196. Xu, D.; Wang, Y. smFRET study of rRNA dimerization at the peptidyl transfer center. Biophysical Chemistry, 2021, 277, 106657. doi: 10.1016/j.bpc.2021.106657
  197. Thuenemann, E.C.; Le, D.H.T.; Lomonossoff, G.P.; Steinmetz, N.F. Bluetongue Virus Particles as Nanoreactors for Enzyme Delivery and Cancer Therapy. Molecular Pharmaceutics, 2021, 18(3), 1150–1156. doi: 10.1021/acs.molpharmaceut.0c01053
  198. Binkhathlan, Z.; Ali, R.; Qamar, W.; Al-Lawati, H.; Lavasanifar, A. Pharmacokinetic and Tissue Distribution of Orally Administered Cyclosporine A-Loaded poly(ethylene oxide)-block-Poly(ε-caprolactone) Micelles versus Sandimmune® in Rats. Pharmaceutical Research, 2021, 38(1), 51–65. doi: 10.1007/s11095-021-02990-5
  199. Bagheri, M.; Fens, M.H.; Kleijn, T.G.; Capomaccio, R.B.; Mehn, D.; Krawczyk, P.M.; Scutigliani, E.M.; Gurinov, A.; Baldus, M.; van Kronenburg, N.C.H.; Kok, R.J.; Heger, M.; van Nostrum, C.F.; Hennink, W.E. In Vitro and In Vivo Studies on HPMA-Based Polymeric Micelles Loaded with Curcumin. Molecular Pharmaceutics, 2021, 18(3), 1247–1263. doi: 10.1021/acs.molpharmaceut.0c01114
  200. Amar-Lewis, E.; Buaron, N.; Chintakunta, R.; Benafsha, C.; Goldbart, R.; Traitel, T.; Prasad, M.; Elkabets, M.; Kost, J. Quaternized Starch-Based Composite Nanoparticles for siRNA Delivery to Tumors. ACS Applied Nano Materials, 2021, 4(2), 2218–2229. doi: 10.1021/acsanm.1c00032
  201. Nam, S.H.; Jang, J.; Cheon, D.H.; Chong, S.-E.; Ahn, J.H.; Hyun, S.; Yu, J.; Lee, Y. pH-Activatable cell penetrating peptide dimers for potent delivery of anticancer drug to triple-negative breast cancer. Journal of Controlled Release, 2021, 330, 898–906. doi: 10.1016/j.jconrel.2020.10.063
  202. Shikov, A.E.; Malovichko, Y.V.; Lobov, A.A.; Belousova, M.E.; Nizhnikov, A.A.; Antonets, K.S. The Distribution of Several Genomic Virulence Determinants Does Not Corroborate the Established Serotyping Classification of Bacillus thuringiensis. International Journal of Molecular Sciences, 2021, 22(5), 2244. doi: 10.3390/ijms22052244
  203. Nomoto, T.; Yao, Y.; Inoue, Y.; Suzuki, M.; Kanamori, K.; Takemoto, H.; Matsui, M.; Tomoda, K.; Nishiyama, N. Fructose-functionalized polymers to enhance therapeutic potential of p-Boronophenylalanine for neutron capture therapy. Journal of Controlled Release, 2021, 332, 184–193. doi: 10.1016/j.jconrel.2021.02.021
  204. Bin Rashed, F.; Stoica, A.C.; MacDonald, D.; El-Saidi, H.; Ricardo, C.; Bhatt, B.; Moore, J.; Diaz-Dussan, D.; Ramamonjisoa, N.; Mowery, Y.; Damaraju, S.; Fahlman, R.; Kumar, P.; Weinfeld, M. Identification of proteins and cellular pathways targeted by 2-nitroimidazole hypoxic cytotoxins. Redox Biology, 2021, 41, 101905. doi: 10.1016/j.redox.2021.101905
  205. Suraweera, A.; Duijf, P.H.G.; Jekimovs, C.; Schrobback, K.; Liu, C.; Adams, M.N.; O'Byrne, K.J.; Richard, D.J. COMMD1, from the Repair of DNA Double Strand Breaks, to a Novel Anti-Cancer Therapeutic Target. Cancers, 2021, 13(4), 830. doi: 10.3390/cancers13040830
  206. Wang, Y.; Xu, X.; Zhao, X.; Yin, Z. Functionalized polymeric hybrid micelles as an efficient nanotheranostic agent for thrombus imaging and thrombolysis. Acta Biomaterialia, 2021, 122, 278–290. doi: 10.1016/j.actbio.2020.10.015
  207. Trac, N.; Chen, L.-Y.; Zhang, A.; Liao, C.-P.; Poon, C.; Wang, J.; Ando, Y.; Joo, J.; Garri, C.; Shen, K.; Kani, K.; Gross, M.E.; Chung, E.J. CCR2-targeted micelles for anti-cancer peptide delivery and immune stimulation. Journal of Controlled Release, 2021, 329, 614–623. doi: 10.1016/j.jconrel.2020.09.054
  208. Yang, Y.; Zhang, Q.; Zhang, J.; Chen, A.; Chen, Y.; Li, S.; Ye, M.; Xuan, X.; Li, X.; He, H.; Wu, J. Natural pollen extract for photothermal therapy. Materials & Design, 2021, 202, 109573. doi: 10.1016/j.matdes.2021.109573
  209. Mizuno, H.L.; Anraku, Y.; Sakuma, I.; Akagi, Y. Design of a Photocleavable Drug Binding Platform for a Novel Remotely Controllable Drug Coated Balloon. Journal of Drug Delivery Science and Technology, 2021, 62, 102375. doi: 10.1016/j.jddst.2021.102375
  210. Nguyen, H.T.; Phung, C.D.; Tran, T.H.; Pham, T.T.; Pham, L.M.; Nguyen, T.T.; Jeong, J.-H.; Choi, H.-G.; Ku, S.K.; Yong, C.S.; Kim, J.O. Manipulating immune system using nanoparticles for an effective cancer treatment: Combination of targeted therapy and checkpoint blockage miRNA. Journal of Controlled Release, 2021, 329, 524–537. doi: 10.1016/j.jconrel.2020.09.034
  211. Seneviratne, U.; Huang, Z.; Am Ende, C.W.; Butler, T.W.; Cleary, L.; Dresselhaus, E.; Evrard, E.; Fisher, E.L.; Green, M.E.; Helal, C.J.; Humphrey, J.M.; Lanyon, L.F.; Marconi, M.; Mukherjee, P.; Sciabola, S.; Steppan, C.M.; Sylvain, E.K.; Tuttle, J.B.; Verhoest, P.R.; Wager, T.T.; Xie, L.; Ramaswamy, G.; Johnson, D.S.; Pettersson, M. Photoaffinity Labeling and Quantitative Chemical Proteomics Identify LXRβ as the Functional Target of Enhancers of Astrocytic apoE. Cell Chemical Biology, 2021, 28(2), 148–157.e7. doi: 10.1016/j.chembiol.2020.09.002
  212. Emami, F.; Pathak, S.; Nguyen, T.T.; Shrestha, P.; Maharjan, S.; Kim, J.O.; Jeong, J.-H.; Yook, S. Photoimmunotherapy with cetuximab-conjugated gold nanorods reduces drug resistance in triple negative breast cancer spheroids with enhanced infiltration of tumor-associated macrophages. Journal of Controlled Release, 2021, 329, 645–664. doi: 10.1016/j.jconrel.2020.10.001
  213. Lapenta, F.; Aupič, J.; Vezzoli, M.; Strmšek, Ž.; Da Vela, S.; Svergun, D.I.; Carazo, J.M.; Melero, R.; Jerala, R. Self-assembly and regulation of protein cages from pre-organised coiled-coil modules. Nature Communications, 2021, 12, 939. doi: 10.1038/s41467-021-21184-6
  214. Aupič, J.; Strmšek, Ž.; Lapenta, F.; Pahovnik, D.; Pisanski, T.; Drobnak, I.; Ljubetič, A.; Jerala, R. Designed folding pathway of modular coiled-coil-based proteins. Nature Communications, 2021, 12, 940. doi: 10.1038/s41467-021-21185-5
  215. Gribanyov, D.; Zhdanov, G.; Olenin, A.; Lisichkin, G.; Gambaryan, A.; Kukushkin, V.; Zavyalova, E. SERS-Based Colloidal Aptasensors for Quantitative Determination of Influenza Virus. International Journal of Molecular Sciences, 2021, 22(4), 1842. doi: 10.3390/ijms22041842
  216. Hull, S.M.; Lindsay, C.D.; Brunel, L.G.; Shiwarski, D.J.; Tashman, J.W.; Roth, J.G.; Myung, D.; Feinberg, A.W.; Heilshorn, S.C. 3D Bioprinting using UNIversal Orthogonal Network (UNION) Bioinks. Advanced Functional Materials, 2021, 31(7), 2007983. doi: 10.1002/adfm.202007983
  217. Ji, M.-L.; Jiang, H.; Wu, F.; Geng, R.; Ya, L.K.; Lin, Y.C.; Xu, J.H.; Wu, X.T.; Lu, J. Precise targeting of miR-141/200c cluster in chondrocytes attenuates osteoarthritis development. Annals of the Rheumatic Diseases, 2021, 80(3), 356–366. doi: 10.1136/annrheumdis-2020-218469
  218. Petrov, R.A.; Mefedova, S.R.; Yamansarov, E.Y.; Maklakova, S.Y.; Grishin, D.A.; Lopatukhina, E.V.; Burenina, O.Y.; Lopukhov, A.V.; Kovalev, S.V.; Timchenko, Y.V.; Ondar, E.E.; Ivanenkov, Y.A.; Evteev, S.A.; Vaneev, A.N.; Timoshenko, R.V.; Klyachko, N.L.; Erofeev, A.S.; Gorelkin, P.V.; Beloglazkina, E.K.; Majouga, A.G. New Small-Molecule Glycoconjugates of Docetaxel and GalNAc for Targeted Delivery to Hepatocellular Carcinoma. Molecular Pharmaceutics, 2021, 18(1), 461–468. doi: 10.1021/acs.molpharmaceut.0c00980
  219. Fang, Y.; Coulter, J.A.; Wu, J.; Liu, L.; Li, X.; Dong, Y.; Ma, L.; Pu, Y.; Sun, B.; Niu, Z.; Jin, J.; Zhao, Y.; Mi, W.; Xu, Y.; Sun, W. Identification of differentially expressed genes involved in amino acid and lipid accumulation of winter turnip rape (Brassica rapa L.) in response to cold stress. PloS ONE, 2021, 16(2), e0245494. doi: 10.1371/journal.pone.0245494
  220. Van Lysebetten, D.; Malfanti, A.; Deswarte, K.; Koynov, K.; Golba, B.; Ye, T.; Zhong, Z.; Kasmi, S.; Lamoot, A.; Chen, Y.; Van Herck, S.; Lambrecht, B.N.; Sanders, Niek N.N.; Lienenklaus, S.; David, S.A.; Vicent, M.J.; De Koker, S.; De Geest, B.G. Lipid-Polyglutamate Nanoparticle Vaccine Platform. ACS Applied Materials & Interfaces, 2021, 13(5), 6011–6022. doi: 10.1021/acsami.0c20607
  221. Phung, C.D.; Tran, T.H.; Choi, J.-Y.; Jeong, J.-H.; Ku, S.K.; Yong, C.S.; Kim, J.O. Pre- and Post-Transcriptional Regulation of cFLIP for Effective Cancer Therapy Using pH-Ultrasensitive Nanoparticles. ACS Applied Materials & Interfaces, 2021, 13(5), 5999–6010. doi: 10.1021/acsami.0c20624
  222. De Luca, S.; Treny, J.; Chen, F.; Seal, P.; Stenzel, M.H.; Smith, S.C. Enhancing Cationic Drug Delivery with Polymeric Carriers: The Coulomb-pH Switch Approach. Advanced Theory and Simulations, 2021, 4(2), 2000247. doi: 10.1002/adts.202000247
  223. Abukar, T.; Rahmani, S.; Thompson, N.K.; Antonescu, C.N.; Wakarchuk, W.W. Development of BODIPY labelled sialic acids as sialyltransferase substrates for direct detection of terminal galactose on N- and O-linked glycans. Carbohydrate Research, 2021, 500, 108249. doi: 10.1016/j.carres.2021.108249
  224. Wang, K.; Kievit, F.M.; Chiarelli, P.A.; Stephen, Z.R.; Lin, G.; Silber, J.R.; Ellenbogen, R.G.; Zhang, M. siRNA Nanoparticle Suppresses Drug-Resistant Gene and Prolongs Survival in an Orthotopic Glioblastoma Xenograft Mouse Model. Advanced Functional Materials, 2021, 31(6), 2007166. doi: 10.1002/adfm.202007166
  225. González, L.F.; Acuña, E.; Arellano, G.; Morales, P.; Sotomayor, P.; Oyarzun-Ampuero, F.; Naves, R. Intranasal delivery of interferon-β-loaded nanoparticles induces control of neuroinflammation in a preclinical model of multiple sclerosis: A promising simple, effective, non-invasive, and low-cost therapy. Journal of Controlled Release, 2021, 331, 443–459. doi: 10.1016/j.jconrel.2020.11.019
  226. Serteyn, L.; Bosquee, E.; Delatour, A.; Rubio-Melendez, M.E.; Vega-Muñoz, K.V.; Ramirez, C.C.; Francis, F. Multi-approach comparative study of the two most prevalent genotypes of pea aphid Acyrthosiphon pisum (Hemiptera: Aphididae) in Chile. Entomological Science, 2021, 24(1), 55–67. doi: 10.1111/ens.12436
  227. Chudinov, A.V.; Vasiliskov, V.A.; Kuznetsova, V.E.; Lapa, S.A.; Kolganova, N.A.; Timofeev, E.N. Mononucleotide repeat expansions with non-natural polymerase substrates. Scientific Reports, 2021, 11, 2423. doi: 10.1038/s41598-021-82150-2
  228. Huo, S.; Zhao, P.; Shi, Z.; Zou, M.; Yang, X.; Warszawik, E.; Loznik, M.; Göstl, R.; Herrmann, A. Mechanochemical bond scission for the activation of drugs. Nature Chemistry, 2021, 13, 131–139. doi: 10.1038/s41557-020-00624-8
  229. Ford, C.A.; Spoonmore, T.J.; Gupta, M.K.; Duvall, C.L.; Guelcher, S.A.; Cassat, J.E. Diflunisal-loaded poly(propylene sulfide) nanoparticles decrease S. aureus-mediated bone destruction during osteomyelitis. Journal of Orthopaedic Research, 2021, 39(2), 426–437. doi: 10.1002/jor.24948
  230. Biosca, A.; Cabanach, P.; Abdulkarim, M.; Gumbleton, M.; Gómez-Canela, C.; Ramírez, M.; Bouzón-Arnáiz, I.; Avalos-Padilla, Y.; Borros, S.; Fernàndez-Busquets, X. Zwitterionic self-assembled nanoparticles as carriers for Plasmodium targeting in malaria oral treatment. Journal of Controlled Release, 2021, 331, 364–375. doi: 10.1016/j.jconrel.2021.01.028
  231. Si, Y.; Xu, Y.; Guan, J.; Chen, K.; Kim, S.; Yang, E.S.; Zhou, L.; Liu, X.M. Anti-EGFR antibody-drug conjugate for triple-negative breast cancer therapy. Engineering in Life Sciences, 2021, 21(1–2), 37–44. doi: 10.1002/elsc.202000027
  232. Shao, S.; Ortega-Rivera, O.A.; Ray, S.; Pokorski, J.K.; Steinmetz, N.F. A Scalable Manufacturing Approach to Single Dose Vaccination against HPV. Vaccines, 2021, 9(1), 66. doi: 10.3390/vaccines9010066
  233. Novoselova, M.V.; German, S.V.; Abakumova, T.O.; Perevoschikov, S.V.; Sergeeva, O.V.; Nesterchuk, M.V.; Efimova, O.I.; Petrov, K.S.; Chernyshev, V.S.; Zatsepin, T.S.; Gorin, D.A. Multifunctional nanostructured drug delivery carriers for cancer therapy: Multimodal imaging and ultrasound-induced drug release. Colloids and Surfaces B: Biointerfaces, 2021, 200, 111576. doi: 10.1016/j.colsurfb.2021.111576
  234. Jiang, H.; Cole, P.A. N-Terminal Protein Labeling with N-Hydroxysuccinimide Esters and Microscale Thermophoresis Measurements of Protein-Protein Interactions Using Labeled Protein. Current Protocols, 2021, 1, e14. doi: 10.1002/cpz1.14
  235. Zhang, Y.; Hughes, K.R.; Raghani, R.M.; Ma, J.; Orbach, S.; Jeruss, J.S.; Shea, L.D. Cargo-free immunomodulatory nanoparticles combined with anti-PD-1 antibody for treating metastatic breast cancer. Biomaterials, 2021, 269, 120666. doi: 10.1016/j.biomaterials.2021.120666
  236. Lim, S.; Kim, W.; Song, S.; Shim, M.K.; Yoon, H.Y.; Kim, B.-S.; Kwon, I.C.; Kim, K. Intracellular Uptake Mechanism of Bioorthogonally Conjugated Nanoparticles on Metabolically Engineered Mesenchymal Stem Cells. Bioconjugate Chemistry, 2021, 32(1), 199–214. doi: 10.1021/acs.bioconjchem.0c00640
  237. Lee, S.Y.; Yang, M.; Seo, J.-H.; Jeong, D.I.; Hwang, C.; Kim, H.-J.; Lee, J.; Lee, K.; Park, J.; Cho, H.-J. Serially pH-Modulated Hydrogels Based on Boronate Ester and Polydopamine Linkages for Local Cancer Therapy. ACS Applied Materials & Interfaces, 2021, 13(2), 2189–2203. doi: 10.1021/acsami.0c16199
  238. Gurevich, D.; Dor, S.; Erov, M.; Dan, Y.; Moy, J.C.; Mairesse, O.; Dafny-Yelin, M.; Adler-Abramovich, L.; Afriat-Jurnou, L. Directed Enzyme Evolution and Encapsulation in Peptide Nanospheres of Quorum Quenching Lactonase as an Antibacterial Treatment against Plant Pathogen. ACS Applied Materials & Interfaces, 2021, 13(2), 2179–2188. doi: 10.1021/acsami.0c15808
  239. Shen, J.Z.; Qiu, Z.; Wu, Q.; Finlay, D.; Garcia, G.; Sun, D.; Rantala, J.; Barshop, W.; Hope, J.L.; Gimple, R.C.; Sangfelt, O.; Bradley, L.M.; Wohlschlegel, J.; Rich, J.N.; Spruck, C. FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells. Cell, 2021, 184(2), 352–369.e23. doi: 10.1016/j.cell.2020.11.042
  240. Lyu, X.; Lei, K.-H.; Biak Sang, P.; Shiva, O.; Chastain, M.; Chi, P.; Chai, W. Human CST complex protects stalled replication forks by directly blocking MRE11 degradation of nascent-strand DNA. EMBO Journal, 2021, 40(2), e103654. doi: 10.15252/embj.2019103654
  241. Pham, L.M.; Kim, E.-C.; Ou, W.; Phung, C.D.; Nguyen, T.T.; Pham, T.T.; Poudel, K.; Gautam, M.; Nguyen, H.T.; Jeong, J.-H.; Yong, C.S.; Park, S.-Y.; Kim, J.-R.; Kim, J.O. Targeting and Clearance of Senescent Foamy Macrophages and Senescent Endothelial Cells by Antibody-Functionalized Mesoporous Silica Nanoparticles for Alleviating Aorta Atherosclerosis. Biomaterials, 2021, 269, 120677. doi: 10.1016/j.biomaterials.2021.120677
  242. Shapoval, O.; Oleksa, V.; Šlouf, M.; Lobaz, V.; Trhlíková, O.; Filipová, M.; Janoušková, O.; Engstová, H.; Pankrác, J.; Modrý, A.; Herynek, V.; Ježek, P.; Šefc, L.; Horák, D. Colloidally Stable P(DMA-AGME)-Ale-Coated Gd(Tb)F3:Tb3+(Gd3+),Yb3+,Nd3+ Nanoparticles as a Multimodal Contrast Agent for Down- and Upconversion Luminescence, Magnetic. Nanomaterials, 2021, 11(1), 230. doi: 10.3390/nano11010230
  243. González, M.I.; González-Arjona, M.; Santos-Coquillat, A.; Vaquero, J.; Vázquez-Ogando, E.; de Molina, A.; Peinado, H.; Desco, M.; Salinas, B. Covalently Labeled Fluorescent Exosomes for In Vitro and In Vivo Applications. Biomedicines, 2021, 9, 81. doi: 10.3390/biomedicines9010081
  244. Wang, Y.; Goun, A.; Laforge, F.; Quine, Z.; Rabitz, H. A key bidirectional switching issue in optogenetics emulated with laser dyes to illustrate its mitigation using nonlinear optical tools. Applied Physics Letters, 2021, 118(2), 024101. doi: 10.1063/5.0035183
  245. Guan, J.; Lu, C.; Jin, Q.; Lu, H.; Chen, X.; Tian, L.; Zhang, Y.; Ortega, J.; Zhang, J.; Siteni, S.; Chen, M.; Gu, L.; Shay, J.W.; Davis, A.J.; Chen, Z.J.; Fu, Y.-X.; Li, G.-M. MLH1 Deficiency-Triggered DNA Hyperexcision by Exonuclease 1 Activates the cGAS-STING Pathway. Cancer Cell, 2021, 39(1), 109–121.e5. doi: 10.1016/j.ccell.2020.11.004
  246. Lu, C.; Guan, J.; Lu, S.; Jin, Q.; Rousseau, B.; Lu, T.; Stephens, D.; Zhang, H.; Zhu, J.; Yang, M.; Ren, Z.; Liang, Y.; Liu, Z.; Han, C.; Liu, L.; Cao, X.; Zhang, A.; Qiao, J.; Batten, K.; Chen, M.; Castrillon, D.H.; Wang, T.; Li, B.; Diaz, L.A.; Li, G.-M.; Fu, Y.-X. DNA Sensing in Mismatch Repair-Deficient Tumor Cells Is Essential for Anti-tumor Immunity. Cancer Cell, 2021, 39(1), 96–108.e6. doi: 10.1016/j.ccell.2020.11.006
  247. Irwin, N.A.T.; Pittis, A.A.; Mathur, V.; Howe, L.J.; Keeling, P.J.; Lynn, D.H.; Bourland, W.A. The Function and Evolution of Motile DNA Replication Systems in Ciliates. Current Biology, 2021, 31(1), 66–76.e6. doi: 10.1016/j.cub.2020.09.077
  248. Bos, I.; Timmerman, M.; Sprakel, J. FRET-Based Determination of the Exchange Dynamics of Complex Coacervate Core Micelles. Macromolecules, 2021, 54(1), 398–411. doi: 10.1021/acs.macromol.0c02387
  249. Zeng, Q.; Deng, H.; Li, Y.; Fan, T.; Liu, Y.; Tang, S.; Wei, W.; Liu, X.; Guo, X.; Jiang, J.; Wang, Y.; Song, D. Berberine Directly Targets the NEK7 Protein to Block the NEK7–NLRP3 Interaction and Exert Anti-inflammatory Activity. Journal of Medicinal Chemistry, 2021, 64(1), 768–781. doi: 10.1021/acs.jmedchem.0c01743
  250. Ridolfo, R.; Tavakoli, S.; Junnuthula, V.; Williams, D.S.; Urtti, A.; van Hest, J.C.M. Exploring the impact of morphology on the properties of biodegradable nanoparticles and their diffusion in complex biological medium. Biomacromolecules, 2021, 22(1), 126–133. doi: 10.1021/acs.biomac.0c00726
  251. Nagai, H.; Tatara, H.; Tanaka-Furuhashi, K.; Kurata, S.; Yano, T. Homeostatic Regulation of ROS-Triggered Hippo-Yki Pathway via Autophagic Clearance of Ref(2)P/p62 in the Drosophila Intestine. Developmental Cell, 2021, 56(1), 81--94.e10. doi: 10.1016/j.devcel.2020.12.007
  252. Gueiderikh, A.; Maczkowiak-Chartois, F.; Rouvet, G.; Souquère-Besse, S.; Apcher, S.; Diaz, J.-J.; Rosselli, F. Fanconi anemia A protein participates in nucleolar homeostasis maintenance and ribosome biogenesis. Science Advances, 2021, 7(1), eabb5414. doi: 10.1126/sciadv.abb5414
  253. Conner, J.W.; Poole, D.P.; Jörg, M.; Veldhuis, N.A. New small molecule fluorescent probes for G protein-coupled receptors: valuable tools for drug discovery. Future Medicinal Chemistry, 2021, 13(1), 63–90. doi: 10.4155/fmc-2019-0327
  254. Park, Y.I.; Kwon, S.-H.; Lee, G.; Motoyama, K.; Kim, M.W.; Lin, M.; Niidome, T.; Choi, J.H.; Lee, R. pH-sensitive multi-drug liposomes targeting folate receptor β for efficient treatment of non-small cell lung cancer. Journal of Controlled Release, 2021, 330, 1–14. doi: 10.1016/j.jconrel.2020.12.011
  255. Novopashina, D.S.; Vorobyeva, M.A.; Lomzov, A.A.; Silnikov, V.N.; Venyaminova, A.G. Terminal Mono- and Bis-Conjugates of Oligonucleotides with Closo-Dodecaborate: Synthesis and Physico-Chemical Properties. International Journal of Molecular Sciences, 2021, 22(1), 182. doi: 10.3390/ijms22010182
  256. Morozov, V.N.; Kolyvanova, M.A.; Dement'eva, O.V.; Rudoy, V.M.; Kuzmin, V.A. Comparison of quenching efficacy of SYBR green I and picoGreen fluorescence by ultrasmall gold nanoparticles in isotropic and liquid-crystalline DNA systems. Journal of Molecular Liquids, 2021, 321, 114751. doi: 10.1016/j.molliq.2020.114751
  257. Anson, F.; Kanjilal, P.; Thayumanavan, S.; Hardy, J.A. Tracking Exogenous Intracellular Casp-3 Using Split GFP. Protein Science, 2021, 30(2), 366–380. doi: 10.1002/pro.3992
  258. DuRoss, A.N.; Landry, M.R.; Thomas, C.R.; Neufeld, M.J.; Sun, C. Fucoidan-coated nanoparticles target radiation-induced P-selectin to enhance chemoradiotherapy in murine colorectal cancer. Cancer Letters, 2021, 500, 208–219. doi: 10.1016/j.canlet.2020.11.021
  259. Martins dos Santos, A.; Bagliotti Meneguin, A.; Taslima Akhter, D.; Fletcher, N.; Houston, Z.H.; Bell, C.; Thurecht, K.J.; Palmira Daflon Gremião, M. Understanding the role of colon-specific microparticles based on retrograded starch/pectin in the delivery of chitosan nanoparticles along the gastrointestinal tract. European Journal of Pharmaceutics and Biopharmaceutics, 2021, 158, 371–378. doi: 10.1016/j.ejpb.2020.12.004
  260. Chetverikov, P.E.; Craemer, C.; Cvrković, T.; Klimov, P.B.; Petanović, R.U.; Romanovich, A.E.; Sukhareva, S.I.; Zukoff, S.N.; Bolton, S.; Amrine, J. Molecular phylogeny of the phytoparasitic mite family Phytoptidae (Acariformes: Eriophyoidea) identified the female genitalic anatomy as a major macroevolutionary factor and revealed multiple origins of gall induction. Experimental & Applied Acarology, 2021, 83(1), 31–68. doi: 10.1007/s10493-020-00571-6
  261. Nechaeva, N.L.; Sorokina, O.N.; Konstantinova, T.S.; Vasilyeva, A.D.; Yurina, L.V.; Byzova, N.A.; Bugrova, A.E.; Yanovich, S.V.; Eremenko, A.V.; Kurochkin, I.N. Simultaneous express immunoassay of multiple cardiac biomarkers with an automatic platform in human plasma. Talanta, 2021, 224, 121860. doi: 10.1016/j.talanta.2020.121860
  262. Thauvin, C.; Maudens, P.; Allémann, E. Microwave-assisted synthesis of self-assembling bi-functionalizable amphiphilic diblock copolymers. Journal of Drug Delivery Science and Technology, 2021, 61, 102255. doi: 10.1016/j.jddst.2020.102255
  263. Prikhozhdenko, E.S.; Gusliakova, O.I.; Kulikov, O.A.; Mayorova, O.A.; Shushunova, N.A.; Abdurashitov, A.S.; Bratashov, D.N.; Pyataev, N.A.; Tuchin, V.V.; Gorin, D.A.; Sukhorukov, G.B.; Sindeeva, O.A. Target delivery of drug carriers in mice kidney glomeruli via renal artery. Balance between efficiency and safety. Journal of Controlled Release, 2021, 329, 175–190. doi: 10.1016/j.jconrel.2020.11.051
  264. Ye, R.; Xu, H.; Gu, J.; Chen, H. Bioinspired synthesis of protein-posnjakite organic-inorganic nanobiohybrid for biosensing applications. Analytica Chimica Acta, 2021, 1143, 31–36. doi: 10.1016/j.aca.2020.11.026
  265. Merlo, R.; Caprioglio, D.; Cillo, M.; Valenti, A.; Mattossovich, R.; Morrone, C.; Massarotti, A.; Rossi, F.; Miggiano, R.; Leonardi, A.; Minassi, A.; Perugino, G. The SNAP-tag technology revised: an effective chemo-enzymatic approach by using a universal azide-based substrate. Journal of Enzyme Inhibition and Medicinal Chemistry, 2021, 36(1), 85–97. doi: 10.1080/14756366.2020.1841182
  266. Zhong, Z.; Deng, X.; Wang, P.; Yu, C.; Kiratitanaporn, W.; Wu, X.; Schimelman, J.; Tang, M.; Balayan, A.; Yao, E.; Tian, J.; Chen, L.; Zhang, K.; Chen, S. Rapid bioprinting of conjunctival stem cell micro-constructs for subconjunctival ocular injection. Biomaterials, 2021, 267, 120462. doi: 10.1016/j.biomaterials.2020.120462
  267. Janczewska, M.; Szkop, M.; Pikus, G.; Kopyra, K.; Świątkowska, A.; Brygoła, K.; Karczmarczyk, U.; Walczak, J.; Żuk, M.T.; Duszak, J.; Ciach, T. PSMA targeted conjugates based on dextran. Applied Radiation and Isotopes, 2021, 167, 109439. doi: 10.1016/j.apradiso.2020.109439
  268. Cuccaro, A.; De Marchi, L.; Oliva, M.; Sanches, M.V.; Freitas, R.; Casu, V.; Monni, G.; Miragliotta, V.; Pretti, C. Sperm quality assessment in Ficopomatus enigmaticus (Fauvel, 1923): Effects of selected organic and inorganic chemicals across salinity levels. Ecotoxicology and Environmental Safety, 2021, 207, 111219. doi: 10.1016/j.ecoenv.2020.111219
  269. Fornasier, M.; Porcheddu, A.; Casu, A.; Raghavan, S.R.; Jönsson, P.; Schillén, K.; Murgia, S. Surface-modified nanoerythrosomes for potential optical imaging diagnostics. Journal of Colloid and Interface Science, 2021, 582, 246–253. doi: 10.1016/j.jcis.2020.08.032
  270. Yao, J.; Huang, X.; Ren, J. In Situ Determination of Secretory Kinase Fam20C from Living Cells Using Fluorescence Correlation Spectroscopy. Talanta, 2021, 232, 122473. doi: 10.1016/j.talanta.2021.122473
  271. Sharoyko, V. V.; Iamalova, N. R.; Ageev, S. V.; Meshcheriakov, A. A.; Iurev, G. O.; Petrov, A. V.; Nerukh, D. A.; Farafonov, V. S.; Vasina, L. V.; Penkova, A. V.; Semenov, K. N. In Vitro and In Silico Investigation of Water-Soluble Fullerenol C60(OH)24: Bioactivity and Biocompatibility. J. Phys. Chem. B, 2021, 125(32), 9197–9212. doi: 10.1021/acs.jpcb.1c03332
  272. Pishesha, N.; Harmand, T.; Smeding, L. Y.; Ma, W.; Ludwig, L. S.; Janssen, R.; Islam, A.; Xie, Y. J.; Fang, T.; McCaul, N.; Pinney, W.; Sugito, H. R.; Rossotti, M. A.; Gonzalez-Sapienza, G.; Ploegh, H. L. Induction of Antigen-Specific Tolerance by Nanobody–Antigen Adducts That Target Class-II Major Histocompatibility Complexes. Nat Biomed Eng, 2021, 5(11), 1389–1401. doi: 10.1038/s41551-021-00738-5
  273. Sakhabutdinova, A. R.; Kamalov, M. I.; Salakhieva, D. V.; Mavzyutov, A. R.; Garafutdinov, R. R. Inhibition of Nonspecific Polymerase Activity Using Poly(Aspartic) Acid as a Model Anionic Polyelectrolyte. Analytical Biochemistry, 2021, 628, 114267. doi: 10.1016/j.ab.2021.114267
  274. Bayin, N. S.; Mizrak, D.; Stephen, D. N.; Lao, Z.; Sims, P. A.; Joyner, A. L. Injury-Induced ASCL1 Expression Orchestrates a Transitory Cell State Required for Repair of the Neonatal Cerebellum. Sci. Adv., 2021, 7(50), eabj1598. doi: 10.1126/sciadv.abj1598
  275. Junnuthula, V.; Sadeghi Boroujeni, A.; Cao, S.; Tavakoli, S.; Ridolfo, R.; Toropainen, E.; Ruponen, M.; van Hest, J. C. M.; Urtti, A. Intravitreal Polymeric Nanocarriers with Long Ocular Retention and Targeted Delivery to the Retina and Optic Nerve Head Region. Pharmaceutics, 2021, 13(4), 445. doi: 10.3390/pharmaceutics13040445.
  276. Kang, Y.; Flores, L.; Ngai, H. W.; Cornejo, Y. R.; Haber, T.; McDonald, M.; Moreira, D. F.; Gonzaga, J. M.; Abidi, W.; Zhang, Y.; Hammad, M.; Kortylewski, M.; Aboody, K. S.; Berlin, J. M. Large, Anionic Liposomes Enable Targeted Intraperitoneal Delivery of a TLR 7/8 Agonist To Repolarize Ovarian Tumors’ Microenvironment. Bioconjugate Chem., 2021, 32(8), 1581–1592. doi: 10.1021/acs.bioconjchem.1c00139
  277. Ganguly, S.; Neelam; Grinberg, I.; Margel, S. Layer by Layer Controlled Synthesis at Room Temperature of Tri-Modal (MRI, Fluorescence and CT) Core/Shell Superparamagnetic IO/Human Serum Albumin Nanoparticles for Diagnostic Applications. Polymers for Advanced Technologies, 2021, 32(10), 3909–3921. doi: 10.1002/pat.5344
  278. Rapoport, E. M.; Khasbiullina, N. R.; Komarova, V. A.; Ryzhov, I. M.; Gorbatch, M. M.; Tuzikov, A. B.; Khaidukov, S. V.; Popova, I. S.; Korchagina, E. Y.; Henry, S. M.; Bovin, N. V. Localization of Synthetic Glycolipids in the Cell and the Dynamics of Their Insertion/Loss. Biochimica et Biophysica Acta (BBA) - Biomembranes, 2021, 1863(9), м. doi: 10.1016/j.bbamem.2021.183645
  279. Nikitin, A. A.; Yurenya, A. Y.; Zatsepin, T. S.; Aparin, I. O.; Chekhonin, V. P.; Majouga, A. G.; Farle, M.; Wiedwald, U.; Abakumov, M. A. Magnetic Nanoparticles as a Tool for Remote DNA Manipulations at a Single-Molecule Level. ACS Appl. Mater. Interfaces, 2021, 13(12), 14458–14469. doi: 10.1021/acsami.0c21002
  280. Sim, T.; Choi, B.; Kwon, S. W.; Kim, K.-S.; Choi, H.; Ross, A.; Kim, D.-H. Magneto-Activation and Magnetic Resonance Imaging of Natural Killer Cells Labeled with Magnetic Nanocomplexes for the Treatment of Solid Tumors. ACS Nano, 2021, 15(8), 12780–12793. doi: 10.1021/acsnano.1c01889
  281. Xu, J.; Zhao, L.; Peng, S.; Chu, H.; Liang, R.; Tian, M.; Connell, P. P.; Li, G.; Chen, C.; Wang, H.-W. Mechanisms of Distinctive Mismatch Tolerance between Rad51 and Dmc1 in Homologous Recombination. Nucleic Acids Research, 2021, 49(22), 13135–13149. doi: 10.1093/nar/gkab1141
  282. Arduino, I.; Liu, Z.; Iacobazzi, R. M.; Lopedota, A. A.; Lopalco, A.; Cutrignelli, A.; Laquintana, V.; Porcelli, L.; Azzariti, A.; Franco, M.; Santos, H. A.; Denora, N. Microfluidic Preparation and in Vitro Evaluation of IRGD-Functionalized Solid Lipid Nanoparticles for Targeted Delivery of Paclitaxel to Tumor Cells. International Journal of Pharmaceutics, 2021, 610, 121246. doi: 10.1016/j.ijpharm.2021.121246
  283. Saouaf, O. M.; Roth, G. A.; Ou, B. S.; Smith, A. A. A.; Yu, A. C.; Gale, E. C.; Grosskopf, A. K.; Picece, V. C. T. M.; Appel, E. A. Modulation of Injectable Hydrogel Properties for Slow Co-Delivery of Influenza Subunit Vaccine Components Enhance the Potency of Humoral Immunity. Journal of Biomedical Materials Research Part A, 2021, 109(11), 2173–2186. doi: 10.1002/jbm.a.37203
  284. Liu, L.; Huang, K.; Li, W.; Qiu, R.; Fang, Y.; Huang, Y.; Zhao, S.; Lv, H.; Zhang, K.; Shan, H.; Li, Y. Molecular Imaging of Collagen Destruction of the Spine. ACS Nano, 2021, 15(12), 19138–19149. doi: 10.1021/acsnano.1c07112
  285. Saidi, A.; Wartenberg, M.; Madinier, J.-B.; Ilango, G.; Seren, S.; Korkmaz, B.; Lecaille, F.; Aucagne, V.; Lalmanach, G. Monitoring Human Neutrophil Activation by a Proteinase 3 Near-Infrared Fluorescence Substrate-Based Probe. Bioconjugate Chem., 2021, 32(8), 1782–1790. doi: 10.1021/acs.bioconjchem.1c00267
  286. Pilipenko, I.; Korzhikov-Vlakh, V.; Valtari, A.; Anufrikov, Y.; Kalinin, S.; Ruponen, M.; Krasavin, M.; Urtti, A.; Tennikova, T. Mucoadhesive Properties of Nanogels Based on Stimuli-Sensitive Glycosaminoglycan-Graft-PNIPAAm Copolymers. International Journal of Biological Macromolecules, 2021, 186, 864–872. doi: 10.1016/j.ijbiomac.2021.07.070
  287. Cursi, L.; Vercellino, S.; M. McCafferty, M.; Sheridan, E.; Petseva, V.; Adumeau, L.; A. Dawson, K. Multifunctional Superparamagnetic Nanoparticles with a Fluorescent Silica Shell for the in Vitro Study of Bio-Nano Interactions at the Subcellular Scale. Nanoscale, 2021, 13(38), 16324–16338. doi: 10.1039/D1NR04582B
  288. Gvozdev, D. A.; Ramonova, А. А.; Slonimskiy, Y. B.; Gudkova, V. R.; Nikelshparg, E. I.; Moisenovich, A. М.; Moisenovich, М. М.; Zaitsev, A. V.; Olshevskaya, V. A.; Paschenko, V. Z.; Maksimov, Е. G. Nanodiamonds as a Platform for Targeted Delivery of Chlorin-Based Photosensitizers to Cancer Cells. Diamond and Related Materials, 2021, 120, 108676. doi: 10.1016/j.diamond.2021.108676
  289. Zhao, P.; Xia, X.; Xu, X.; Leung, K. K. C.; Rai, A.; Deng, Y.; Yang, B.; Lai, H.; Peng, X.; Shi, P.; Zhang, H.; Chiu, P. W. Y.; Bian, L. Nanoparticle-Assembled Bioadhesive Coacervate Coating with Prolonged Gastrointestinal Retention for Inflammatory Bowel Disease Therapy. Nat Commun, 2021, 12(1), 7162. doi: 10.1038/s41467-021-27463-6
  290. Kwon, S. P.; Hwang, B.-H.; Park, E.-H.; Kim, H. Y.; Lee, J.-R.; Kang, M.; Song, S. Y.; Jung, M.; Sohn, H. S.; Kim, E.; Kim, C. W.; Lee, K. Y.; Oh, G. C.; Choo, E.; Lim, S.; Chung, Y.; Chang, K.; Kim, B.-S. Nanoparticle-Mediated Blocking of Excessive Inflammation for Prevention of Heart Failure Following Myocardial Infarction. Small, 2021, 17(32), 2101207. doi: 10.1002/smll.202101207
  291. Choi, H.; Kwon, M.; Choi, H. E.; Hahn, S. K.; Kim, K. S. Non-Invasive Topical Drug-Delivery System Using Hyaluronate Nanogels Crosslinked via Click Chemistry. Materials, 2021, 14(6), 1504. doi: 10.3390/ma14061504
  292. Yu, J. H.; Steinberg, I.; Davis, R. M.; Malkovskiy, A. V.; Zlitni, A.; Radzyminski, R. K.; Jung, K. O.; Chung, D. T.; Curet, L. D.; D’Souza, A. L.; Chang, E.; Rosenberg, J.; Campbell, J.; Frostig, H.; Park, S.; Pratx, G.; Levin, C.; Gambhir, S. S. Noninvasive and Highly Multiplexed Five-Color Tumor Imaging of Multicore Near-Infrared Resonant Surface-Enhanced Raman Nanoparticles In Vivo. ACS Nano, 2021, 15(12), 19956–19969. doi: 10.1021/acsnano.1c07470
  293. van der Post, S.; Birchenough, G. M. H.; Held, J. M. NOX1-Dependent Redox Signaling Potentiates Colonic Stem Cell Proliferation to Adapt to the Intestinal Microbiota by Linking EGFR and TLR Activation. Cell Reports, 2021, 35(1), 108949. doi: 10.1016/j.celrep.2021.108949
  294. Ticho, A. L.; Calzadilla, N.; Malhotra, P.; Lee, H.; Anbazhagan, A. N.; Saksena, S.; Dudeja, P. K.; Lee, D.; Gill, R. K.; Alrefai, W. A. NPC1L1-Dependent Transport of 27-Alkyne Cholesterol in Intestinal Epithelial Cells. American Journal of Physiology-Cell Physiology, 2021, 320(5), C916–C925. doi: 10.1152/ajpcell.00062.2021
  295. DeJulius, C. R.; Dollinger, B. R.; Kavanaugh, T. E.; Dailing, E.; Yu, F.; Gulati, S.; Miskalis, A.; Zhang, C.; Uddin, J.; Dikalov, S.; Duvall, C. L. Optimizing an Antioxidant TEMPO Copolymer for Reactive Oxygen Species Scavenging and Anti-Inflammatory Effects in Vivo. Bioconjugate Chem, 2021, 32(5), 928–941. doi: 10.1021/acs.bioconjchem.1c00081
  296. Abdurashitov, A. S.; Prikhozhdenko, E. S.; Mayorova, O. A.; Plastun, V. O.; Gusliakova, O. I.; Shushunova, N. A.; Kulikov, O. A.; Tuchin, V. V.; Sukhorukov, G. B.; Sindeeva, O. A. Optical Coherence Microangiography of the Mouse Kidney for Diagnosis of Circulatory Disorders. Biomed. Opt. Express, BOE, 2021, 12(7), 4467–4477. doi: 10.1364/BOE.430393
  297. Poudel, S.; Napit, P. R.; Briski, K. P.; Mattheolabakis, G. Oral Delivery of Nucleic Acids with Passive and Active Targeting to the Intestinal Tissue Using Polymer-Based Nanocarriers. Pharmaceutics, 2021, 13(7), 1075. doi: 10.3390/pharmaceutics13071075
  298. Lee, S.; Kim, H. J.; Park, J.-I.; Cho, H. B.; Park, J. S.; Park, K.-H. Organelle Targeting Using a Fluorescent Probe That Selectively Penetrates the Zona Pellucida. International Journal of Pharmaceutics, 2021, 610, 121282. doi: 10.1016/j.ijpharm.2021.121282
  299. Talamini, L.; Picchetti, P.; Ferreira, L. M.; Sitia, G.; Russo, L.; Violatto, M. B.; Travaglini, L.; Fernandez Alarcon, J.; Righelli, L.; Bigini, P.; De Cola, L. Organosilica Cages Target Hepatic Sinusoidal Endothelial Cells Avoiding Macrophage Filtering. ACS Nano, 2021, 15(6), 9701–9716.. doi: 10.1021/acsnano.1c00316
  300. Chapman, D. V.; Hinckley, J. A.; Erstling, J. A.; Estroff, L. A.; Wiesner, U. B. Orthogonal Nanoprobes Enabling Two-Color Optical Super-Resolution Microscopy Imaging of the Two Domains of Diblock Copolymer Thin Film Nanocomposites. Chem. Mater., 2021, 33(13), 5156–5167. doi: 10.1021/acs.chemmater.1c01204
  301. Tsao, W.; Buj, R.; Aird, K. M.; Sidorova, J. M.; Eckert, K. A. Overexpression of Oncogenic H-Ras in HTERT-Immortalized and SV40-Transformed Human Cells Targets Replicative and Specialized DNA Polymerases for Depletion. PLOS ONE, 2021, 16(5), e0251188. doi: 10.1371/journal.pone.0251188
  302. Guarin, M.; Ny, A.; De Croze, N.; Maes, J.; Léonard, M.; Annaert, P.; de Witte, P. A. M. Pharmacokinetics in Zebrafish Embryos (ZFE) Following Immersion and Intrayolk Administration: A Fluorescence-Based Analysis. Pharmaceuticals, 2021, 14(6), 576. doi: 10.3390/ph14060576
  303. Cao, S.; Shao, J.; Wu, H.; Song, S.; De Martino, M. T.; Pijpers, I. A. B.; Friedrich, H.; Abdelmohsen, L. K. E. A.; Williams, D. S.; van Hest, J. C. M. Photoactivated Nanomotors via Aggregation Induced Emission for Enhanced Phototherapy. Nat Commun, 2021, 12(1), 2077. doi: 10.1038/s41467-021-22279-w
  304. van Vliet, T.; Varela-Eirin, M.; Wang, B.; Borghesan, M.; Brandenburg, S. M.; Franzin, R.; Evangelou, K.; Seelen, M.; Gorgoulis, V.; Demaria, M. Physiological Hypoxia Restrains the Senescence-Associated Secretory Phenotype via AMPK-Mediated MTOR Suppression. Molecular Cell, 2021, 81(9), 2041-2052.e6. doi: 10.1016/j.molcel.2021.03.018
  305. Tong, O.; Duette, G.; O’Neil, T. R.; Royle, C. M.; Rana, H.; Johnson, B.; Popovic, N.; Dervish, S.; Brouwer, M. A. E.; Baharlou, H.; Patrick, E.; Ctercteko, G.; Palmer, S.; Lee, E.; Hunter, E.; Harman, A. N.; Cunningham, A. L.; Nasr, N. Plasmacytoid Dendritic Cells Have Divergent Effects on HIV Infection of Initial Target Cells and Induce a Pro-Retention Phenotype. PLOS Pathogens, 2021, 17(4), e1009522. doi: 10.1371/journal.ppat.1009522
  306. Hang, Y.; Tang, S.; Tang, W.; Větvička, D.; Zhang, C.; Xie, Y.; Yu, F.; Yu, A.; Sil, D.; Li, J.; Singh, R. K.; Oupický, D. Polycation Fluorination Improves Intraperitoneal SiRNA Delivery in Metastatic Pancreatic Cancer. Journal of Controlled Release, 2021, 333, 139–150. doi: 10.1016/j.jconrel.2021.03.028
  307. Qi, Y.; Li, J.; Nie, Q.; Gao, M.; Yang, Q.; Li, Z.; Li, Q.; Han, S.; Ding, J.; Li, Y.; Zhang, J. Polyphenol-Assisted Facile Assembly of Bioactive Nanoparticles for Targeted Therapy of Heart Diseases. Biomaterials, 2021, 275, 120952. doi: 10.1016/j.biomaterials.2021.120952
  308. Kim, J.; Kim, J.-M.; Ha, M.; Oh, J.-W.; Nam, J.-M. Polysorbate- and DNA-Mediated Synthesis and Strong, Stable, and Tunable Near-Infrared Photoluminescence of Plasmonic Long-Body Nanosnowmen. ACS Nano, 2021, 15(12), 19853–19863. doi: 10.1021/acsnano.1c07319
  309. Cresti, J. R.; Manfredonia, A. J.; Bragança, C. E.; Boscia, J. A.; Hurley, C. M.; Cundiff, M. D.; Kraut, D. A. Proteasomal Conformation Controls Unfolding Ability. Proceedings of the National Academy of Sciences, 2021, 118(25), e2101004118. doi: 10.1073/pnas.2101004118
  310. Niu, X.; Sun, R.; Chen, Z.; Yao, Y.; Zuo, X.; Chen, C.; Fang, X. Pseudoknot Length Modulates the Folding, Conformational Dynamics, and Robustness of Xrn1 Resistance of Flaviviral XrRNAs. Nat Commun, 2021, 12(1), 6417. doi: 10.1038/s41467-021-26616-x
  311. Kicková, E.; Salmaso, S.; Mastrotto, F.; Caliceti, P.; Urtti, A. Pullulan Based Bioconjugates for Ocular Dexamethasone Delivery. Pharmaceutics, 2021, 13(6), 791. doi: 10.3390/pharmaceutics13060791
  312. Yin, Q.; Pan, A.; Chen, B.; Wang, Z.; Tang, M.; Yan, Y.; Wang, Y.; Xia, H.; Chen, W.; Du, H.; Chen, M.; Fu, C.; Wang, Y.; Yuan, X.; Lu, Z.; Zhang, Q.; Wang, Y. Quantitative Imaging of Intracellular Nanoparticle Exposure Enables Prediction of Nanotherapeutic Efficacy. Nat Commun, 2021, 12(1), 2385. doi: 10.1038/s41467-021-22678-z
  313. Li, H.; Li, X.; Chen, L.; Li, B.; Dong, H.; Liu, H.; Yang, X.; Ueda, H.; Dong, J. Quench-Release-Based Fluorescent Immunosensor for the Rapid Detection of Tumor Necrosis Factor α. ACS Omega, 2021, 6(46), 31009–31016. doi: 10.1021/acsomega.1c03941
  314. Shih, T.-Y.; Najibi, A. J.; Bartlett, A. L.; Li, A. W.; Mooney, D. J. Ultrasound-Triggered Release Reveals Optimal Timing of CpG-ODN Delivery from a Cryogel Cancer Vaccine. Biomaterials, 2021, 279, 121240. doi: 10.1016/j.biomaterials.2021.121240
  315. Usuelli, M.; Meyer, T.; Mezzenga, R.; Mitsi, M. VEGF and VEGFR2 Bind to Similar PH-Sensitive Sites on Fibronectin, Exposed by Heparin-Mediated Conformational Changes. Journal of Biological Chemistry, 2021, 296, 100584. doi: 10.1016/j.jbc.2021.100584
  316. Rickert-Zacharias, V.; Schultz, M.; Mall, M. A.; Schultz, C. Visualization of Ectopic Serine Protease Activity by Förster Resonance Energy Transfer-Based Reporters. ACS Chem. Biol., 2021, 16(11), 2174–2184.. doi: 10.1021/acschembio.1c00168
  317. Zhang, Y.; Yin, Y.; Zhang, W.; Li, H.; Wang, T.; Yin, H.; Sun, L.; Su, C.; Zhang, K.; Xu, H. Reactive Oxygen Species Scavenging and Inflammation Mitigation Enabled by Biomimetic Prussian Blue Analogues Boycott Atherosclerosis. Journal of Nanobiotechnology, 2021, 19(1), 161. doi: 10.1186/s12951-021-00897-2
  318. Ng, S. C.; Güttler, T.; Görlich, D. Recapitulation of Selective Nuclear Import and Export with a Perfectly Repeated 12mer GLFG Peptide. Nat Commun, 2021, 12(1), 4047. doi: 10.1038/s41467-021-24292-5
  319. Mattila, J. T.; Beaino, W.; White, A. G.; Nyiranshuti, L.; Maiello, P.; Tomko, J.; Frye, L. J.; Fillmore, D.; Scanga, C. A.; Lin, P. L.; Flynn, J. L.; Anderson, C. J. Retention of 64Cu-FLFLF, a Formyl Peptide Receptor 1-Specific PET Probe, Correlates with Macrophage and Neutrophil Abundance in Lung Granulomas from Cynomolgus Macaques. ACS Infect. Dis., 2021, 7(8), 2264–2276. doi: 10.1021/acsinfecdis.0c00826
  320. Kotlar, R. M.; Jones, N. D.; Senavirathne, G.; Gardner, A. M.; Messer, R. K.; Tan, Y. Y.; Rabe, A. J.; Fishel, R.; Yoder, K. E. Retroviral Prototype Foamy Virus Intasome Binding to a Nucleosome Target Does Not Determine Integration Efficiency. Journal of Biological Chemistry, 2021, 296, 100550. doi: 10.1016/j.jbc.2021.100550
  321. Rex, R.; Siddhanta, S.; Barman, I. Role of Aqueous-Phase Calcination in Synthesis of Ultra-Stable Dye-Embedded Fluorescent Nanoparticles for Cellular Probing. Appl Spectrosc, 2021, 75(8), 1012–1021. doi: 10.1177/00037028211027597
  322. Diaz-Salmeron, R.; Michel, J.-P.; Hadji, H.; Gout, E.; Vivès, Romain. R.; Ponchel, G.; Bouchemal, K. Role of the Interactions of Soft Hyaluronan Nanomaterials with CD44 and Supported Bilayer Membranes in the Cellular Uptake. Colloids and Surfaces B: Biointerfaces, 2021, 205, 111916. doi: 10.1016/j.colsurfb.2021.111916
  323. Goryunova, M. S.; Arzhanik, V. K.; Zavriev, S. K.; Ryazantsev, D. Y. Rolling Circle Amplification with Fluorescently Labeled DUTP—Balancing the Yield and Degree of Labeling. Anal Bioanal Chem, 2021, 413(14), 3737–3748. doi: 10.1007/s00216-021-03322-7
  324. Zhao, Y.; Liu, R.; Fan, Y.; Zhao, B.; Qian, W.; Guo, J.; Li, C.; Chen, S.; Luo, G.; Deng, H.; Zhang, J. Self-Sealing Hemostatic and Antibacterial Needles by Polyphenol-Assisted Surface Self-Assembly of Multifunctional Nanoparticles. Chemical Engineering Journal, 2021, 425, 130621. doi: 10.1016/j.cej.2021.130621
  325. Zisis, T.; Schwarz, J.; Balles, M.; Kretschmer, M.; Nemethova, M.; Chait, R.; Hauschild, R.; Lange, J.; Guet, C.; Sixt, M.; Zahler, S. Sequential and Switchable Patterning for Studying Cellular Processes under Spatiotemporal ControlACS Appl. Mater. Interfaces 2021, 13 (30), 35545–35560. https://doi.org/. ACS Appl. Mater. Interfaces, 2021, 13(30), 35545–35560. doi: 10.1021/acsami.1c09850
  326. Zisis, T.; Schwarz, J.; Balles, M.; Kretschmer, M.; Nemethova, M.; Chait, R.; Hauschild, R.; Lange, J.; Guet, C.; Sixt, M.; Zahler, S. Sequential and Switchable Patterning for Studying Cellular Processes under Spatiotemporal Control. ACS Appl. Mater. Interfaces, 2021, 13(30), 35545–35560. doi: 10.1021/acsami.1c09850
  327. Sapozhnikova, Y. P.; Koroleva, A. G.; Yakhnenko, V. M.; Khanaev, I. V.; Glyzina, O. Y.; Avezova, T. N.; Volkova, A. A.; Mushinskaya, A. V.; Tyagun, M. L.; Shagun, A. N.; Makarov, M. M.; Kirilchik, S. V.; Sudakov, N. P.; Klimenkov, I. V.; Sukhanova, L. V. Sex Associated Effects of Noise Pollution in Stone Sculpin (Paracottus Knerii) as a Model Object in the Context of Human-Induced Rapid Environmental Change. Biology, 2021, 10(10), 1063. doi: 10.3390/biology10101063
  328. Nishiyama, K.; Maeki, M.; Ishida, A.; Tani, H.; Hisamoto, H.; Tokeshi, M. Simple Approach for Fluorescence Signal Amplification Utilizing a Poly(Vinyl Alcohol)-Based Polymer Structure in a Microchannel. ACS Omega, 2021, 6(12), 8340–8345. doi: 10.1021/acsomega.1c00057
  329. Yang, Z.; Xu, H.; Wang, J.; Chen, W.; Zhao, M. Single-Molecule Fluorescence Techniques for Membrane Protein Dynamics Analysis. Appl Spectrosc, 2021, 75(5), 491–505. doi: 10.1177/00037028211009973
  330. Reddi, R. N.; Rogel, A.; Resnick, E.; Gabizon, R.; Prasad, P. K.; Gurwicz, N.; Barr, H.; Shulman, Z.; London, N. Site-Specific Labeling of Endogenous Proteins Using CoLDR Chemistry. J. Am. Chem. Soc., 2021, 143(48), 20095–20108. doi: 10.1021/jacs.1c06167
  331. Robinson, N. J.; Miyagi, M.; Scarborough, J. A.; Scott, J. G.; Taylor, D. J.; Schiemann, W. P. SLX4IP Promotes RAP1 SUMOylation by PIAS1 to Coordinate Telomere Maintenance through NF-ΚB and Notch Signaling. Science Signaling, 2021, 14(689), eabe9613. doi: 10.1126/scisignal.abe9613
  332. Gonzalez-Valdivieso, J.; Garcia-Sampedro, A.; Hall, A. R.; Girotti, A.; Arias, F. J.; Pereira, S. P.; Acedo, P. Smart Nanoparticles as Advanced Anti-Akt Kinase Delivery Systems for Pancreatic Cancer Therapy. ACS Appl. Mater. Interfaces, 2021, 13(47), 55790–55805. doi: 10.1021/acsami.1c14592
  333. Lobov, A. A.; Babkina, I. Y.; Danilov, L. G.; Masharskiy, A. E.; Predeus, A. V.; Mikhailova, N. A.; Granovitch, A. I.; Maltseva, A. L. Species-Specific Proteins in the Oviducts of Snail Sibling Species: Proteotranscriptomic Study of Littorina Fabalis and L. Obtusata. Biology, 2021, 10(11), 1087. doi: 10.3390/biology10111087
  334. Huynh, G. T.; Henderson, E. C.; Frith, J. E.; Meagher, L.; Corrie, S. R. Stability and Performance Study of Fluorescent Organosilica PH Nanosensors. Langmuir, 2021, 37(21), 6578–6587. doi: 10.1021/acs.langmuir.1c00936
  335. Shalaeva, A. Y.; Kostyuchenko, R. P.; Kozin, V. V. Structural and Functional Characterization of the FGF Signaling Pathway in Regeneration of the Polychaete Worm Alitta Virens (Annelida, Errantia). Genes, 2021, 12(6), 788. doi: 10.3390/genes12060788
  336. Patel, N.; Ji, N.; Wang, Y.; Li, X.; Langley, N.; Tan, C. Subcutaneous Delivery of Albumin: Impact of Thermosensitive Hydrogels. AAPS PharmSciTech, 2021, 22(3), 120. doi: 10.1208/s12249-021-01982-3
  337. Hofmeister, A.; Jahn-Hofmann, K.; Brunner, B.; Helms, M. W.; Metz-Weidmann, C.; Krack, A.; Kurz, M.; Li, Z.; Weitzenberg, M. M.; Pflimlin, E.; Plettenburg, O.; Scheidler, S. Syntheses of Morpholine-Based Nucleotide Analogs for Hepatic SiRNA Targeting and Stabilization. J. Med. Chem., 2021, 64(10), 6838–6855. doi: 10.1021/acs.jmedchem.1c00144
  338. Machulkin, A. E.; Shafikov, R. R.; Uspenskaya, A. A.; Petrov, S. A.; Ber, A. P.; Skvortsov, D. A.; Nimenko, E. A.; Zyk, N. U.; Smirnova, G. B.; Pokrovsky, V. S.; Abakumov, M. A.; Saltykova, I. V.; Akhmirov, R. T.; Garanina, A. S.; Polshakov, V. I.; Saveliev, O. Y.; Ivanenkov, Y. A.; Aladinskaya, A. V.; Finko, A. V.; Yamansarov, E. U.; Krasnovskaya, O. O.; Erofeev, A. S.; Gorelkin, P. V.; Dontsova, O. A.; Beloglazkina, E. K.; Zyk, N. V.; Khazanova, E. S.; Majouga, A. G. Synthesis and Biological Evaluation of PSMA Ligands with Aromatic Residues and Fluorescent Conjugates Based on Them. J. Med. Chem., 2021, 64(8), 4532–4552. doi: 10.1021/acs.jmedchem.0c01935
  339. Tuzikov, A. B.; Rapoport, E. M.; Khaidukov, S. V.; Nokel, E. A.; Knirel, Y. A.; Bovin, N. V. Synthesis of Bodipy-Labeled Bacterial Polysaccharides and Their Interaction with Human Dendritic Cells. Glycoconj J, 2021, 38(3), 369–374. doi: 10.1007/s10719-021-09993-9
  340. Lin, G.; Mu, Q.; Revia, R.; Stephen, Z.; Jeon, M.; Zhang, M. A highly selective iron oxide-based imaging nanoparticle for long-term monitoring of drug-induced tumor cell apoptosis. Biomaterials Science, 2021, 9(2), 471-481. doi: 10.1039/d0bm00518e
  341. Sanman, L.E.; Chen, I.W.; Bieber, J.M.; Steri, V.; Trentesaux, C.; Hann, B.; Klein, O.D.; Wu, L.F.; Altschuler, S.J. Transit-amplifying cells coordinate changes in intestinal epithelial cell type composition. Developmental Cell, 2021, 56(3), 356-365.e9. doi: 10.1016/j.devcel.2020.12.020
  342. Goldman, D.H.; Livingston, N.M.; Movsik, J.; Wu, B.; Green, R. Live-cell imaging reveals kinetic determinants of quality control triggered by ribosome stalling. Molecular Cell, 2021, 81(8), 1830-1840.E8. doi: 10.1016/j.molcel.2021.01.029
  343. Sun, H.; Yan, L.; Zhang, R.; Lovell, J.F.; Wu, Y.; Cheng, C. A Sulfobetaine Zwitterionic Polymer-Drug Conjugate for Multivalent Paclitaxel and Gemcitabine Co-Delivery. Biomaterials Science, 2021, 9(14), 5000-5010. doi: 10.1039/d1bm00393c
  344. Usama, S.M.; Zhao, B.; Burgess, K. Fluorescent Kinase Inhibitors As Probes In Cancer. Chemical Society Reviews, 2021, 50(17), 9794-9816. doi: 10.1039/d1cs00017a
  345. Gilpin, A.; Zeng, Y.; Hoque, J.; Ryu, J.H.; Yang, Y.; Zauscher, S.; Eward, W.; Varghese, S. Self-healing of hyaluronic acid to improve in vivo retention and function. Advanced Healthcare Materials, 2021, 10(23), e2100777. doi: 10.1002/adhm.202100777
  346. Mersch, K.; Ozturk, T.N.; Park, K.; Lim, H.-H.; Robertson, J.L. Altering CLC stoichiometry by reducing non-polar side-chains at the dimerization interface. Journal of molecular biology, 2021, 433(8), 166886. doi: 10.1016/j.jmb.2021.166886
  347. Savage, D.T.; Hilt, J.Z.; Dziubla, T.D. Assessing the Perfluoroalkyl Acid-Induced Swelling of Förster Resonance Energy Transfer-Capable Poly( N -Isopropylacrylamide) Microgels. Soft Matter, 2021, 17(42), 9799-9808. doi: 10.1039/d1sm00985k
  348. Atalis, A.; Dixon, J.B.; Roy, K. Soluble and Microparticle-based Delivery of TLR4 and TLR9 Agonists Differentially Modulate 3D Chemotaxis of Bone Marrow-derived Dendritic Cells. Advanced Healthcare Materials, 2021, 10(15), e2001899. doi: 10.1002/adhm.202001899
  349. Martin, J.R.; Howard, M.L.T.; Wang, S.; Berger, A.G.; Hammond, P.T. Oxidation-responsive, tunable growth factor delivery from polyelectrolyte-coated implants. Advanced Healthcare Materials, 2021, 10(9), e2001941. doi: 10.1002/adhm.202001941
  350. Fleisher, R.C.; Michael, N.; Gonzalez, R.L. Mechanistic studies of non-canonical amino acid mutagenesis. Methods in enzymology, 2021, 656, 375-428. doi: 10.1016/bs.mie.2021.05.001
  351. Mathew, B.; Aoyagi, K.L.; Fisher, M.A. Yersinia pestis lipopolysaccharide remodeling confers resistance to a Xenopsylla cheopis cecropin. ACS Infectious Diseases, 2021, 7(8), 2536-2545. doi: 10.1021/acsinfecdis.1c00275
  352. Reisbeck, F.; Ozimkovski, A.; Cherri, M.; Dimde, M.; Quaas, E.; Mohammadifar, E.; Achazi, K.; Haag, R. Gram Scale Synthesis of Dual-Responsive Dendritic Polyglycerol Sulfate as Drug Delivery System. Polymers, 2021, 13(6), 982. doi: 10.3390/polym13060982
  353. Kofoed Andersen, C.; Khatri, S.; Hansen, J.; Slott, S.; Pavan Parvathaneni, R.; Mendes, A.C.; Chronakis, I.S.; Hung, S.-C.; Rajasekaran, N.; Ma, Z.; Zhu, S.; Dai, H.; Mellins, E.D.; Astakhova, K. Carbon Nanotubes—Potent Carriers for Targeted Drug Delivery in Rheumatoid Arthritis. Pharmaceutics, 2021, 13(4), 453. doi: 10.3390/pharmaceutics13040453
  354. Junnuthula, V.; Sadeghi Boroujeni, A.; Cao, S.; Tavakoli, S.; Ridolfo, R.; Toropainen, E.; Ruponen, M.; van Hest, J.C.M.; Urtti, A. Intravitreal Polymeric Nanocarriers with Long Ocular Retention and Targeted Delivery to the Retina and Optic Nerve Head Region. Pharmaceutics, 2021, 13(4), 445. doi: 10.3390/pharmaceutics13040445
  355. Tian, T.; Cao, L.; He, C.; Ye, Q.; Liang, R.; You, W.; Zhang, H.; Wu, J.; Ye, J.; Tannous, B.A.; Gao, J. Targeted delivery of neural progenitor cell-derived extracellular vesicles for anti-inflammation after cerebral ischemia. Theranostics, 2021, 11(13), 6507-6521. doi: 10.7150/thno.56367
  356. Vasil’eva, I.; Moor, N.; Anarbaev, R.; Kutuzov, M.; Lavrik, O. Functional Roles of PARP2 in Assembling Protein–Protein Complexes Involved in Base Excision DNA Repair. International Journal of Molecular Sciences, 2021, 22(9), 4679. doi: 10.3390/ijms22094679
  357. Stambaugh, A.; Parks, J.W.; Stott, M.A.; Meena, G.G.; Hawkins, A.R.; Schmidt, H. Optofluidic multiplex detection of single SARS-CoV-2 and influenza A antigens using a novel bright fluorescent probe assay. Proceedings of the National Academy of Sciences of the United States of America, 2021, 118(20), e2103480118. doi: 10.1073/pnas.2103480118
  358. Guarin, M.; Faelens, R.; Giusti, A.; De Croze, N.; Léonard, M.; Cabooter, D.; Annaert, P.; de Witte, P.; Ny, A. Spatiotemporal imaging and pharmacokinetics of fluorescent compounds in zebrafish eleuthero-embryos after different routes of administration. Scientific Reports, 2021, 11, 12229. doi: 10.1038/s41598-021-91612-6
  359. Swetledge, S.; Carter, R.; Stout, R.; Astete, C.E.; Jung, J.P.; Sabliov, C.M. Stability and ocular biodistribution of topically administered PLGA nanoparticles. Scientific Reports, 2021, 11, 12270. doi: 10.1038/s41598-021-90792-5
  360. Arunagiri, V.; Tsai, H.-C.; Darge, H.F.; Hanurry, E.Y.; Lee, C.Y.; Lai, J.-Y.; Wu, S.-Y. Enhanced Cellular Uptake in an Electrostatically Interacting Fucoidan–L-Arginine Fiber Complex. Polymers, 2021, 13(11), 1795. doi: 10.3390/polym13111795
  361. Li, M.; Ruwe, H.; Melzer, M.; Junker, A.; Hensel, G.; Tschiersch, H.; Schwenkert, S.; Chamas, S.; Schmitz-Linneweber, C.; Börner, T.; Stein, N. The Arabidopsis AAC Proteins CIL and CIA2 Are Sub-functionalized Paralogs Involved in Chloroplast Development. Frontiers in Plant Science, 2021, 12, 681375. doi: 10.3389/fpls.2021.681375
  362. Małodobra-Mazur, M.; Cierzniak, A.; Kaliszewski, K.; Dobosz, T. PPARG Hypermethylation as the First Epigenetic Modification in Newly Onset Insulin Resistance in Human Adipocytes. Genes, 2021, 12(6), 889. doi: 10.3390/genes12060889
  363. Zavyalova, E.; Ambartsumyan, O.; Zhdanov, G.; Gribanyov, D.; Gushchin, V.; Tkachuk, A.; Rudakova, E.; Nikiforova, M.; Kuznetsova, N.; Popova, L.; Verdiev, B.; Alatyrev, A.; Burtseva, E.; Ignatieva, A.; Iliukhina, A.; Dolzhikova, I.; Arutyunyan, A.; Gambaryan, A.; Kukushkin, V. SERS-Based Aptasensor for Rapid Quantitative Detection of SARS-CoV-2. Nanomaterials, 2021, 11(6), 1394. doi: 10.3390/nano11061394
  364. Mercier, E.; Wang, X.; Maiti, M.; Wintermeyer, W.; Rodnina, M.V. Lateral gate dynamics of the bacterial translocon during cotranslational membrane protein insertion. Proceedings of the National Academy of Sciences of the United States of America, 2021, 118(26), e2100474118. doi: 10.1073/pnas.2100474118
  365. Nonga, O.E.; Lavogina, D.; Enkvist, E.; Kestav, K.; Chaikuad, A.; Dixon-Clarke, S.E.; Bullock, A.N.; Kopanchuk, S.; Ivan, T.; Ekambaram, R.; Viht, K.; Knapp, S.; Uri, A. Crystal Structure-Guided Design of Bisubstrate Inhibitors and Photoluminescent Probes for Protein Kinases of the PIM Family. Molecules, 2021, 26(14), 4353. doi: 10.3390/molecules26144353
  366. Vorobyeva, M.A.; Dymova, M.A.; Novopashina, D.S.; Kuligina, E.V.; Timoshenko, V.V.; Kolesnikov, I.A.; Taskaev, S.Y..; Richter, V.A.; Venyaminova, A.G. Tumor Cell-Specific 2′-Fluoro RNA Aptamer Conjugated with Closo -Dodecaborate as A Potential Agent for Boron Neutron Capture Therapy. International Journal of Molecular Sciences, 2021, 22(14), 7326. doi: 10.3390/ijms22147326
  367. Itzhaki, E.; Hadad, E.; Moskovits, N.; Stemmer, S.M.; Margel, S. Tumor-Targeted Fluorescent Proteinoid Nanocapsules Encapsulating Synergistic Drugs for Personalized Cancer Therapy. Pharmaceuticals, 2021, 14(7), 648. doi: 10.3390/ph14070648
  368. Zhang, Q.; Li, S.; Cai, L.; Zhu, Y.; Duan, X.; Jiang, P.; Zhong, L.; Guo, K.; Tong, R. Microenvironment Activatable Nanoprodrug Based on Gripper-like Cyclic Phenylboronic Acid to Precisely and Effectively Alleviate Drug-induced Hepatitis. Theranostics, 2021, 11(17), 8301-8321. doi: 10.7150/thno.61214
  369. Gambles, M.T.; Li, J.; Wang, J.; Sborov, D.; Yang, J.; Kopeček, J. Crosslinking of CD38 Receptors Triggers Apoptosis of Malignant B Cells. Molecules, 2021, 26(15), 4658. doi: 10.3390/molecules26154658
  370. Fisher, F.; Zhang, Y.; Vincent, P.F.Y.; Gajewiak, J.; Gordon, T.J.; Glowatzki, E.; Fuchs, P.A.; McIntosh, J.M. Cy3-RgIA-5727 Labels and Inhibits α9-Containing nAChRs of Cochlear Hair Cells. Frontiers in Cellular Neuroscience, 2021, 15, 697560. doi: 10.3389/fncel.2021.697560
  371. Sargiacomo, C.; Stonehouse, S.; Moftakhar, Z.; Sotgia, F.; Lisanti, M.P. MitoTracker Deep Red (MTDR) Is a Metabolic Inhibitor for Targeting Mitochondria and Eradicating Cancer Stem Cells (CSCs), With Anti-Tumor and Anti-Metastatic Activity In Vivo. Frontiers in Oncology, 2021, 11, 678343. doi: 10.3389/fonc.2021.678343
  372. Rasi, V.; Wood, D.C.; Eickhoff, C.S.; Xia, M.; Pozzi, N.; Edwards, R.L.; Walch, M.; Bovenschen, N.; Hoft, D.F. Granzyme A Produced by γ 9 δ 2 T Cells Activates ER Stress Responses and ATP Production, and Protects Against Intracellular Mycobacterial Replication Independent of Enzymatic Activity. Frontiers in Immunology, 2021, 12, 712678. doi: 10.3389/fimmu.2021.712678
  373. Andreev-Andrievskiy, A.A.; Zinovkin, R.A.; Mashkin, M.A.; Frolova, O.Y..; Kazaishvili, Y.G.; Scherbakova, V.S.; Rudoy, B.A.; Nesterenko, V.G. Gene Expression Pattern of Peyer’s Patch Lymphocytes Exposed to Kagocel Suggests Pattern-Recognition Receptors Mediate Its Action. Frontiers in Pharmacology, 2021, 12, 679511. doi: 10.3389/fphar.2021.679511
  374. Grosskopf, A.K.; Correa, S.; Baillet, J.; Maikawa, C.L.; Gale, E.C.; Brown, R.A.; Appel, E.A. Consistent tumorigenesis with self-assembled hydrogels enables high-powered murine cancer studies. Communications Biology, 2021, 4, 985. doi: 10.1038/s42003-021-02500-8
  375. Adameyko, K.I.; Burakov, A.V.; Finoshin, A.D.; Mikhailov, K.V.; Kravchuk, O.I.; Kozlova, O.S.; Gornostaev, N.G.; Cherkasov, A.V.; Erokhov, P.A.; Indeykina, M.I.; Bugrova, A.E.; Kononikhin, A.S.; Moiseenko, A.V.; Sokolova, O.S.; Bonchuk, A.N.; Zhegalova, I.V.; Georgiev, A.A.; Mikhailov, V.S.; Gogoleva, N.E.; Gazizova, G.R.; Shagimardanova, E.I.; Gusev, O.A.; Lyupina, Y.V. Conservative and Atypical Ferritins of Sponges. International Journal of Molecular Sciences, 2021, 22(16), 8635. doi: 10.3390/ijms22168635
  376. Zhukova, V.; Osipova, N.; Semyonkin, A.; Malinovskaya, J.; Melnikov, P.; Valikhov, M.; Porozov, Y.; Solovev, Y.; Kuliaev, P.; Zhang, E.; Sabel, B.A.; Chekhonin, V.; Abakumov, M.; Majouga, A.; Kreuter, J.; Henrich-Noack, P.; Gelperina, S.; Maksimenko, O. Fluorescently Labeled PLGA Nanoparticles for Visualization In Vitro and In Vivo: The Importance of Dye Properties. Pharmaceutics, 2021, 13(8), 1145. doi: 10.3390/pharmaceutics13081145
  377. Chen, X.; Tao, Y.; He, M.; Deng, M.; Guo, R.; Sheng, Q.; Wang, X.; Ren, K.; Li, T.; He, X.; Zang, S.; Zhang, Z.; Li, M.; He, Q. Co-delivery of autophagy inhibitor and gemcitabine using a pH-activatable core-shell nanobomb inhibits pancreatic cancer progression and metastasis. Theranostics, 2021, 11(18), 8692-8705. doi: 10.7150/thno.60437
  378. Wang, Y.; Wang, Q.; Feng, W.; Yuan, Q.; Qi, X.; Chen, S.; Yao, P.; Dai, Q.; Xia, P.; Zhang, D.; Sun, F. Folic acid-modified ROS-responsive nanoparticles encapsulating luteolin for targeted breast cancer treatment. Drug Delivery, 2021, 28(1), 1695-1708. doi: 10.1080/10717544.2021.1963351
  379. Zhang, L.; Yang, C.; Li, Y.; Niu, S.; Liang, X.; Zhang, Z.; Luo, Q.; Luo, H. Dynamic Changes in the Levels of Amyloid-β 42 Species in the Brain and Periphery of APP/PS1 Mice and Their Significance for Alzheimer’s Disease. Frontiers in Molecular Neuroscience, 2021, 14, 723317. doi: 10.3389/fnmol.2021.723317
  380. Paul, M.; Tannenberg, R.; Tscheuschner, G.; Ponader, M.; Weller, M.G. Cocaine Detection by a Laser-Induced Immunofluorometric Biosensor. Biosensors, 2021, 11(9), 313. doi: 10.3390/bios11090313
  381. Bai, X.; Liu, W.; Jin, S.; Zhao, W.; Xu, Y.; Zhou, Z.; Chen, S.; Pan, L. Facile Generation of Potent Bispecific Fab via Sortase A and Click Chemistry for Cancer Immunotherapy. Cancers, 2021, 13(18), 4540. doi: 10.3390/cancers13184540
  382. Sekulovski, S.; Devant, P.; Panizza, S.; Gogakos, T.; Pitiriciu, A.; Heitmeier, K.; Ramsay, E.P.; Barth, M.; Schmidt, C.; Tuschl, T.; Baas, F.; Weitzer, S.; Martinez, J.; Trowitzsch, S. Assembly defects of human tRNA splicing endonuclease contribute to impaired pre-tRNA processing in pontocerebellar hypoplasia. Nature Communications, 2021, 12, 5610. doi: 10.1038/s41467-021-25870-3
  383. Li, M.; Hensel, G.; Melzer, M.; Junker, A.; Tschiersch, H.; Ruwe, H.; Arend, D.; Kumlehn, J.; Börner, T.; Stein, N. Mutation of the ALBOSTRIANS Ohnologous Gene HvCMF3 Impairs Chloroplast Development and Thylakoid Architecture in Barley. Frontiers in Plant Science, 2021, 12, 732608. doi: 10.3389/fpls.2021.732608
  384. Semikolenova, O.; Sakovina, L.; Akhmetova, E.; Kim, D.; Vokhtantsev, I.; Golyshev, V.; Vorobyeva, M.; Novopashin, S.; Novopashina, D. Photoactivatable nanoCRISPR/Cas9 System Based on crRNA Reversibly Immobilized on Carbon Nanoparticles. International Journal of Molecular Sciences, 2021, 22(20), 10919. doi: 10.3390/ijms222010919
  385. Levit, M.; Vdovchenko, A.; Dzhuzha, A.; Zashikhina, N.; Katernyuk, E.; Gostev, A.; Sivtsov, E.; Lavrentieva, A.; Tennikova, T.; Korzhikova-Vlakh, E. Self-Assembled Nanoparticles Based on Block-Copolymers of Poly(2-Deoxy-2-methacrylamido- d -glucose)/Poly( N -Vinyl Succinamic Acid) with Poly( O -Cholesteryl Methacrylate) for Delivery of Hydrophobic Drugs. International Journal of Molecular Sciences, 2021, 22(21), 11457. doi: 10.3390/ijms222111457
  386. Dymova, M.A.; Utkin, Y.A.; Dmitrieva, M.D.; Kuligina, E.V.; Richter, V.A. Modification of a Tumor-Targeting Bacteriophage for Potential Diagnostic Applications. Molecules, 2021, 26(21), 6564. doi: 10.3390/molecules26216564
  387. Nyabuto, G.O.; Wilson, J.P.; Heilman, S.A.; Kalb, R.C.; Kopacz, J.P.; Abnave, A.V.; Vestal, D.J. The Large GTPase, GBP-2, Regulates Rho Family GTPases to Inhibit Migration and Invadosome Formation in Breast Cancer Cells. Cancers, 2021, 13(22), 5632. doi: 10.3390/cancers13225632
  388. Maluchenko, N.V.; Nilov, D.K.; Pushkarev, S.V.; Kotova, E.Y.; Gerasimova, N.S.; Kirpichnikov, M.P.; Langelier, M.-F.; Pascal, J.M.; Akhtar, M..S.; Feofanov, A.V.; Studitsky, V.M. Mechanisms of Nucleosome Reorganization by PARP1. International Journal of Molecular Sciences, 2021, 22(22), 12127. doi: 10.3390/ijms222212127
  389. Shaskolskiy, B.; Kandinov, I.; Kravtsov, D.; Vinokurova, A.; Gorshkova, S.; Filippova, M.; Kubanov, A.; Solomka, V.; Deryabin, D.; Dementieva, E.; Gryadunov, D. Hydrogel Droplet Microarray for Genotyping Antimicrobial Resistance Determinants in Neisseria gonorrhoeae Isolates. Polymers, 2021, 13(22), 3889. doi: 10.3390/polym13223889
  390. Sapozhnikova, K.A.; Misyurin, V.A.; Ryazantsev, D.Y.; Kokin, E.A.; Finashutina, Y.P.; Alexeeva, A.V.; Ivanov, I.A.; Kocharovskaya, M.V.; Tikhonova, N.A.; Popova, G.P.; Alferova, V.A.; Ustinov, A.V.; Korshun, V.A.; Brylev, V.A. Sensitive Immunofluorescent Detection of the PRAME Antigen Using a Practical Antibody Conjugation Approach. International Journal of Molecular Sciences, 2021, 22(23), 12845. doi: 10.3390/ijms222312845
  391. Moussaron, A.; Jouan-Hureaux, V.; Collet, C.; Pierson, J.; Thomas, N.; Choulier, L.; Veran, N.; Doyen, M.; Arnoux, P.; Maskali, F.; Dumas, D.; Acherar, S.; Barberi-Heyob, M.; Frochot, C. Preliminary Study of New Gallium-68 Radiolabeled Peptide Targeting NRP-1 to Detect Brain Metastases by Positron Emission Tomography. Molecules, 2021, 26(23), 7273. doi: 10.3390/molecules26237273
  392. Jones, J.A.; McMahon, N.P.; Zheng, T.; Eng, J.; Chin, K.; Kwon, S.; Nederlof, M.A.; Gray, J.W.; Gibbs, S.L. Oligonucleotide conjugated antibody strategies for cyclic immunostaining. Scientific Reports, 2021, 11, 23844. doi: 10.1038/s41598-021-03135-9
  393. Eldridge, M.J.G.; Hamon, M.A. Histone H3 deacetylation promotes host cell viability for efficient infection by Listeria monocytogenes. PLoS Pathogens, 2021, 17(12), e1010173. doi: 10.1371/journal.ppat.1010173
  394. Madden, P.J.; Arif, M.S.; Becker, M.E.; McRaven, M.D.; Carias, A.M.; Lorenzo-Redondo, R.; Xiao, S.; Midkiff, C.C.; Blair, R.V.; Potter, E.L.; Martin-Sancho, L.; Dodson, A.; Martinelli, E.; Todd, J.-P.M.; Villinger, F.J.; Chanda, S.K.; Aye, P.P.; Roy, C.J.; Roederer, M.; Lewis, M.G.; Veazey, R.S.; Hope, T.J. Development of an In Vivo Probe to Track SARS-CoV-2 Infection in Rhesus Macaques. Frontiers in Immunology, 2021, 12, 810047. doi: 10.3389/fimmu.2021.810047
  395. Lu, S.; Ye, Q.; Singh, D.; Cao, Y.; Diedrich, J.K.; Yates, J.R.; Villa, E.; Cleveland, D.W.; Corbett, K.D. The SARS-CoV-2 nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein. Nature Communications, 2021, 12, 502. doi: 10.1038/s41467-020-20768-y
  396. Song, J.Y.; Griffin, J.D.; Larson, N.R.; Christopher, M.A.; Middaugh, C.R.; Berkland, C.J. Synthetic Cationic Autoantigen Mimics Glatiramer Acetate Persistence at the Site of Injection and Is Efficacious Against Experimental Autoimmune Encephalomyelitis. Frontiers in Immunology, 2021, 11, 603029. doi: 10.3389/fimmu.2020.603029
  397. Koval, L.; Zemskaya, N.; Aliper, A.; Zhavoronkov, A.; Moskalev, A. Evaluation of the geroprotective effects of withaferin A in Drosophila melanogaster. Aging (Albany NY), 2021, 13(2), 1817-1841. doi: 10.18632/aging.202572
  398. van der Zouwen, A.J.; Jeucken, A.; Steneker, R.; Hohmann, K.F.; Lohse, J.; Slotboom, D.J.; Witte, M.D. Iminoboronates as Dual‐Purpose Linkers in Chemical Probe Development. Chem. Eur. J., 2021, 27(10), 3292-3296. doi: 10.1002/chem.202005115
  399. Dastpeyman, M.; Karas, J.A.; Amin, A.; Turner, B.J.; Shabanpoor, F. Modular Synthesis of Trifunctional Peptide-oligonucleotide Conjugates via Native Chemical Ligation. Frontiers in Chemistry, 2021, 9, 627329. doi: 10.3389/fchem.2021.627329
  400. Mendez, A.S.; Ly, M.; González-Sánchez, A.M.; Hartenian, E.; Ingolia, N.T.; Cate, J.H.; Glaunsinger, B.A. The N-terminal domain of SARS-CoV-2 nsp1 plays key roles in suppression of cellular gene expression and preservation of viral gene expression. Cell Reports, 2021, 37(3), 109841. doi: 10.1016/j.celrep.2021.109841
  401. Skubalova, Z.; Rex, S.; Sukupova, M.; Zahalka, M.; Skladal, P.; Pribyl, J.; Michalkova, H.; Weerasekera, A.; Adam, V.; Heger, Z. Passive Diffusion vs Active pH-Dependent Encapsulation of Tyrosine Kinase Inhibitors Vandetanib and Lenvatinib into Folate-Targeted Ferritin Delivery System. International Journal of Nanomedicine, 2021, 16, 1-14. doi: 10.2147/IJN.S275808
  402. Diederichs, T.; Tampé, R. Single Cell-like Systems Reveal Active Unidirectional and Light-Controlled Transport by Nanomachineries. ACS Nano, 2021, 15(4), 6747-6755. doi: 10.1021/acsnano.0c10139
  403. Shi, X.; Li, Q.; Dai, Z.; Tran, A.A.; Feng, S.; Ramirez, A.D.; Lin, Z.; Wang, X.; Chow, T.T.; Chen, J.; Kumar, D.; McColloch, A.R.; Reiter, J.F.; Huang, E.J.; Seiple, I.B.; Huang, B. Label-retention expansion microscopy. The Journal of Cell Biology, 2021, 220(9), e202105067. doi: 10.1083/jcb.202105067
  404. Tivon, B.; Gabizon, R.; Somsen, B.A.; Cossar, P.J.; Ottmann, C.; London, N. Covalent flexible peptide docking in Rosetta. Chemical Science, 2021, 12(32), 10836-10847. doi: 10.1039/d1sc02322e
  405. Lee, K.S.; Lee, J.; Kim, H.K.; Yeom, S.H.; Woo, C.H.; Jung, Y.J.; Yun, Y.E.; Park, S.Y.; Han, J.; Kim, E.; Sul, J.H.; Jung, J.M.; Park, J.H.; Choi, J.S.; Cho, Y.W.; Jo, D.‐G. Extracellular vesicles from adipose tissue‐derived stem cells alleviate osteoporosis through osteoprotegerin and miR‐21‐5p. Journal of Extracellular Vesicles, 2021, 10(12), e12152. doi: 10.1002/jev2.12152
  406. Zartner, L.; Maffeis, V.; Schoenenberger, C.-A.; Dinu, I.A.; Palivan, C.G. Membrane protein channels equipped with a cleavable linker for inducing catalysis inside nanocompartments. Journal of Materials Chemistry. B, 2021, 9(43), 9012-9022. doi: 10.1039/d1tb01463c
  407. Ezeani, M.; Noor, A.; Alt, K.; Lal, S.; Donnelly, P.S.; Hagemeyer, C.E.; Niego, B.’. Collagen‐Targeted Peptides for Molecular Imaging of Diffuse Cardiac Fibrosis. Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021, 10(18), e022139. doi: 10.1161/JAHA.121.022139

2020

  1. Su, D.; Tsai, H.-I.; Xu, Z.; Yan, F.; Wu, Y.; Xiao, Y.; Liu, X.; Wu, Y.; Parvanian, S.; Zhu, W.; Eriksson, J. E.; Wang, D.; Zhu, H.; Chen, H.; Cheng, F. Exosomal PD-L1 Functions as an Immunosuppressant to Promote Wound Healing. Journal of Extracellular Vesicles, 2020, 9(1), 1709262. doi: 10.1080/20013078.2019.1709262.
  2. Gori, A.; Romanato, A.; Bergamaschi, G.; Strada, A.; Gagni, P.; Frigerio, R.; Brambilla, D.; Vago, R.; Galbiati, S.; Picciolini, S.; Bedoni, M.; Daaboul, G.G.; Chiari, M.; Cretich, M. Membrane-binding peptides for extracellular vesicles on-chip analysis. Journal of Extracellular Vesicles, 2020, 9(1), 1751428. doi: 10.1080/20013078.2020.1751428
  3. Molotkov, A.; Doubrovin, M.; Bhatt, N.; Hsu, F.-C.; Beserra, A.; Chopra, R.; Mintz, A. 3D optical/CT as a preclinical companion imaging platform for glioblastoma drug development. Drug Delivery, 2020, 27(1), 1686-1694. doi: 10.1080/10717544.2020.1833381
  4. Xu, L.; Faruqu, F.N.; Liam-or, R.; Abu Abed, O.; Li, D.; Venner, K.; Errington, R.J.; Summers, H.; Wang, J.T.-W.; Al-Jamal, K.T. Design of experiment (DoE)-driven in vitro and in vivo uptake studies of exosomes for pancreatic cancer delivery enabled by copper-free click chemistry-based labelling. Journal of Extracellular Vesicles, 2020, 9(1), 1779458. doi: 10.1080/20013078.2020.1779458
  5. Perdue, L.A.; Do, P.; David, C.; Chyong, A.; Kellner, A.V.; Ruggieri, A.; Kim, H.R.; Salaita, K.; Lesinski, G.B.; Porter, C.C.; Dreaden, E.C. Optical Control of Cytokine Signaling via Bioinspired, Polymer-Induced Latency. Biomacromolecules, 2020, 21(7), 2635-2644. doi: 10.1021/acs.biomac.0c00264
  6. Janiszewski, T.; Kołt, S.; Kaiserman, D.; Snipas, S. J.; Li, S.; Kulbacka, J.; Saczko, J.; Bovenschen, N.; Salvesen, G.; Drąg, M.; Bird, P. I.; Kasperkiewicz, P. Noninvasive Optical Detection of Granzyme B from Natural Killer Cells with Enzyme-Activated Fluorogenic Probes. Journal of Biological Chemistry, 2020, 295(28), 9567–9582. doi: 10.1074/jbc.RA120.013204
  7. Toyonaga, T.; Steinbach, E. C.; Keith, B. P.; Barrow, J. B.; Schaner, M. R.; Wolber, E. A.; Beasley, C.; Huling, J.; Wang, Y.; Allbritton, N. L.; Chaumont, N.; Sadiq, T. S.; Koruda, M. J.; Jain, A.; Long, M. D.; Barnes, E. L.; Herfarth, H. H.; Isaacs, K. L.; Hansen, J. J.; Shanahan, M. T.; Rahbar, R.; Furey, T. S.; Sethupathy, P.; Sheikh, S. Z. Decreased Colonic Activin Receptor-Like Kinase 1 Disrupts Epithelial Barrier Integrity in Patients With Crohn’s Disease. Cellular and Molecular Gastroenterology and Hepatology, 2020, 10(4), 779–796. doi: 10.1016/j.jcmgh.2020.06.005
  8. Wang, Y.; Yao, J.; Cai, L.; Liu, T.; Wang, X.; Zhang, Y.; Zhou, Z.; Li, T.; Liu, M.; Lai, R.; Liu, X. Bone-Targeted Extracellular Vesicles from Mesenchymal Stem Cells for Osteoporosis Therapy. IJN, 2020, 15, 7967–7977. doi: 10.2147/IJN.S263756
  9. Wang, Y.; Kathiresan, V.; Chen, Y.; Hu, Y.; Jiang, W.; Bai, G.; Liu, G.; Qin, P. Z.; Fang, X. Posttranscriptional Site-Directed Spin Labeling of Large RNAs with an Unnatural Base Pair System under Non-Denaturing Conditions. Chem. Sci., 2020, 11(35), 9655–9664. doi: 10.1039/D0SC01717E
  10. Mohammad-Beigi, H.; Hayashi, Y.; Zeuthen, C. M.; Eskandari, H.; Scavenius, C.; Juul-Madsen, K.; Vorup-Jensen, T.; Enghild, J. J.; Sutherland, D. S. Mapping and Identification of Soft Corona Proteins at Nanoparticles and Their Impact on Cellular Association. Nature Communications, 2020, 11(1), 4535. doi: 10.1038/s41467-020-18237-7
  11. Bakker, R.; Mani, M.; Carthew, R. W. The Wg and Dpp Morphogens Regulate Gene Expression by Modulating the Frequency of Transcriptional Bursts. eLife, 2020, 9, e56076. doi: 10.7554/eLife.56076
  12. Poreba, M.; Groborz, K. M.; Rut, W.; Pore, M.; Snipas, S. J.; Vizovisek, M.; Turk, B.; Kuhn, P.; Drag, M.; Salvesen, G. S. Multiplexed Probing of Proteolytic Enzymes Using Mass Cytometry-Compatible Activity-Based Probes. J. Am. Chem. Soc, 2020, 142(39), 16704–16715. doi: 10.1021/jacs.0c06762
  13. Ast, J.; Arvaniti, A.; Fine, N. H. F.; Nasteska, D.; Ashford, F. B.; Stamataki, Z.; Koszegi, Z.; Bacon, A.; Jones, B. J.; Lucey, M. A.; Sasaki, S.; Brierley, D. I.; Hastoy, B.; Tomas, A.; D’Agostino, G.; Reimann, F.; Lynn, F. C.; Reissaus, C. A.; Linnemann, A. K.; D’Este, E.; Calebiro, D.; Trapp, S.; Johnsson, K.; Podewin, T.; Broichhagen, J.; Hodson, D. J. Super-Resolution Microscopy Compatible Fluorescent Probes Reveal Endogenous Glucagon-like Peptide-1 Receptor Distribution and Dynamics. Nature Communications, 2020, 11(1), 467. doi: 10.1038/s41467-020-14309-w
  14. Haider, N.; Dutt, P.; van de Kooij, B.; Ho, J.; Palomero, L.; Pujana, M. A.; Yaffe, M.; Stambolic, V. NEK10 Tyrosine Phosphorylates P53 and Controls Its Transcriptional Activity. Oncogene, 2020, 39(30), 5252–5266. doi: 10.1038/s41388-020-1361-x
  15. Park, D.J.; Yun, W.S.; Kim, W.C.; Park, J.-E.; Lee, S.H.; Ha, S.; Choi, J.S.; Key, J.; Seo, Y.J. Improvement of stem cell-derived exosome release efficiency by surface modified nanoparticles. Journal of Nanobiotechnology, 2020, 18(1), 178. doi: 10.1186/s12951-020-00739-7
  16. Bitarishvili, S. V. and Bondarenko, V. S. and Geras'kin, S. A. Expression of Gibberelline Biosynthesis and Catabolism Genes in the Embryos of γ-Irradiated Barley Seeds. Biology Bulletin, 2020, 47(11), 1558–1563. doi: 10.1134/S1062359020110059
  17. Molotkov, A.; Bhatt, N.; Doubrovin, M.; Castrillon, J.; Massa, C.; Gerber, A.; D'Armiento, J.; Goldklang, M.; Mintz, A. Multimodality molecular imaging of the alveolar-capillary barrier in lung disease using albumin based optical and PET tracers. Molecular Biomedicine, 2020, 1(1), 17. doi: 10.1186/s43556-020-00020-1
  18. Gusev, I.D.; Firsov, A.M.; Chertkova, R.V.; Kotova, E.A.; Dolgikh, D.A.; Kirpichnikov, M.P.; Antonenko, Y.N. Study of Interaction of Fluorescent Cytochrome C with Liposomes, Mitochondria, and Mitoplasts by Fluorescence Correlation Spectroscopy. Russian Journal of Bioorganic Chemistry, 2020, 46(6), 1162–1171. doi: 10.1134/S1068162020060084
  19. Liu, Z.; Yuan, J.; Lasorella, A.; Iavarone, A.; Bruce, J.N.; Canoll, P.; Sims, P.A. Integrating single-cell RNA-seq and imaging with SCOPE-seq2. Scientific Reports, 2020, 10, 19482. doi: 10.1038/s41598-020-76599-w
  20. Wang, J.; Li, T.; Wang, J.-L.; Xu, Z.; Meng, W.; Wu, Q.-F. Talpid3-Mediated Centrosome Integrity Restrains Neural Progenitor Delamination to Sustain Neurogenesis by Stabilizing Adherens Junctions. Cell Reports, 2020, 33(11), 108495. doi: 10.1016/j.celrep.2020.108495
  21. Peng, B.; Tong, Z.; Tong, W.Y.; Pasic, P.J.; Oddo, A.; Dai, Y.; Luo, M.; Frescene, J.; Welch, N.G.; Easton, C.D.; Thissen, H.; Voelcker, N.H. In Situ Surface Modification of Microfluidic Blood–Brain-Barriers for Improved Screening of Small Molecules and Nanoparticles. ACS Applied Materials & Interfaces, 2020, 12(51), 56753–56766. doi: 10.1021/acsami.0c17102
  22. Poudel, K.; Banstola, A.; Gautam, M.; Soe, Z.; Phung, C.D.; Pham, L.M.; Jeong, J.-H.; Choi, H.-G.; Ku, S.K.; Tran, T.H.; Yong, C.S.; Kim, J.O. Macrophage-Membrane-Camouflaged Disintegrable and Excretable Nanoconstruct for Deep Tumor Penetration. ACS Applied Materials & Interfaces, 2020, 12(51), 56767–56781. doi: 10.1021/acsami.0c17235
  23. Boersma, S.; Rabouw, H.H.; Bruurs, L.J.M.; Pavlovič, T.; van Vliet, A.L.W.; Beumer, J.; Clevers, H.; van Kuppeveld, F.J.M.; Tanenbaum, M.E. Translation and Replication Dynamics of Single RNA Viruses. Cell, 2020, 183(7), 1930–1945.e23. doi: 10.1016/j.cell.2020.10.019
  24. Brachi, G.; Ruiz-Ramírez, J.; Dogra, P.; Wang, Z.; Cristini, V.; Ciardelli, G.; Rostomily, R.C.; Ferrari, M.; Mikheev, A.M.; Blanco, E.; Mattu, C. Intratumoral injection of hydrogel-embedded nanoparticles enhances retention in glioblastoma. Nanoscale, 2020, 12(46), 23838–23850. doi: 10.1039/d0nr05053a
  25. Yang, S.-J.; Huang, C.-H.; Yang, J.-C.; Wang, C.-H.; Shieh, M.-J. Residence Time-Extended Nanoparticles by Magnetic Field Improve the Eradication Efficiency of Helicobacter pylori. ACS Applied Materials & Interfaces, 2020, 12(49), 54316–54327. doi: 10.1021/acsami.0c13101
  26. Qiu, C.-X.; Bai, X.-F.; Shen, Y.; Zhou, Z.; Pan, L.-Q.; Xu, Y.-C.; Zhao, W.-B.; Chen, S.-Q. Specific Inhibition of Tumor Growth by T Cell Receptor-Drug Conjugates Targeting Intracellular Cancer-Testis Antigen NY-ESO-1/LAGE-1. Bioconjugate Chemistry, 2020, 31(12), 2767–2778. doi: 10.1021/acs.bioconjchem.0c00548
  27. Som, M.; Lal, R.; Ruiz-Velasco, V. Lipid-Encapsulated Silica Nanobowls as an Efficient and Versatile DNA Delivery System. Bioconjugate Chemistry, 2020, 31(12), 2697–2711. doi: 10.1021/acs.bioconjchem.0c00493
  28. Gunasekaran, P.; Yim, M.S.; Ahn, M.; Soung, N.-K.; Park, J.-E.; Kim, J.; Bang, G.; Shin, S.C.; Choi, J.; Kim, M.; Kim, H.N.; Lee, Y.-H.; Chung, Y.-H.; Lee, K.; Kim, E.E.; Jeon, Y.-H.; Kim, M.J.; Lee, K.-R.; Kim, B.-Y.; Lee, K.S.; Ryu, E.K.; Bang, J.K. Development of a Polo-like Kinase-1 Polo-Box Domain Inhibitor as a Tumor Growth Suppressor in Mice Models. Journal of Medicinal Chemistry, 2020, 63(23), 14905–14920. doi: 10.1021/acs.jmedchem.0c01451
  29. Teng, F.-Y.; Wang, T.-T.; Guo, H.-L.; Xin, B.-G.; Sun, B.; Dou, S.-X.; Xi, X.-G.; Hou, X.-M. The HRDC domain oppositely modulates the unwinding activity of E. coli RecQ helicase on duplex DNA and G-quadruplex. The Journal of Biological Chemistry, 2020, 295, 17646–17658. doi: 10.1074/jbc.RA120.015492
  30. Volz, J.; Kusch, C.; Beck, S.; Popp, M.; Vögtle, T.; Meub, M.; Scheller, I.; Heil, H.S.; Preu, J.; Schuhmann, M.K.; Hemmen, K.; Premsler, T.; Sickmann, A.; Heinze, K.G.; Stegner, D.; Stoll, G.; Braun, A.; Sauer, M.; Nieswandt, B. BIN2 orchestrates platelet calcium signaling in thrombosis and thrombo-inflammation. Journal of Clinical Investigation, 2020, 130(11), 6064–6079. doi: 10.1172/JCI136457
  31. Wang, Y.; van Steenbergen, M.J.; Beztsinna, N.; Shi, Y.; Lammers, T.; van Nostrum, C.F.; Hennink, W.E. Biotin-decorated all-HPMA polymeric micelles for paclitaxel delivery. Journal of Controlled Release, 2020, 328, 970–984. doi: 10.1016/j.jconrel.2020.09.013
  32. Huayamares, S.G.; Song, J.Y.; Huang, A.; Crowl, S.R.; Groer, C.E.; Forrest, M.L.; Berkland, C.J. Constructing a Biomaterial to Simulate Extracellular Drug Transport in Solid Tumors. Macromolecular Bioscience, 2020, 20(12), 2000251. doi: 10.1002/mabi.202000251
  33. Deol, K.K.; Crowe, S.O.; Du, J.; Bisbee, H.A.; Guenette, R.G.; Strieter, E.R. Proteasome-Bound UCH37/UCHL5 Debranches Ubiquitin Chains to Promote Degradation. Molecular Cell, 2020, 80(5), 796–809.e9. doi: 10.1016/j.molcel.2020.10.017
  34. Chen, D.; Wang, Z.; Zhao, Y.G.; Zheng, H.; Zhao, H.; Liu, N.; Zhang, H. Inositol Polyphosphate Multikinase Inhibits Liquid-Liquid Phase Separation of TFEB to Negatively Regulate Autophagy Activity. Developmental Cell, 2020, 55(5), 588–602.e7. doi: 10.1016/j.devcel.2020.10.010
  35. Altenburg, W.J.; Yewdall, N.A.; Vervoort, D.F.M.; van Stevendaal, M.H.M.E.; Mason, A.F.; van Hest, J.C.M. Programmed spatial organization of biomacromolecules into discrete, coacervate-based protocells. Nature Communications, 2020, 11, 6282. doi: 10.1038/s41467-020-20124-0
  36. Wang, Z.; Cui, M.; Shah, A.M.; Tan, W.; Liu, N.; Bassel-Duby, R.; Olson, E.N. Cell-Type-Specific Gene Regulatory Networks Underlying Murine Neonatal Heart Regeneration at Single-Cell Resolution. Cell Reports, 2020, 33(10), 108472. doi: 10.1016/j.celrep.2020.108472
  37. Clavé, G.; Vasseur, J.-J.; Smietana, M. The Sulfo-Click Reaction and Dual Labeling of Nucleosides. Current Protocols in Nucleic Acid Chemistry, 2020, 83(1), e120. doi: 10.1002/cpnc.120
  38. Huang, D.; Yue, F.; Qiu, J.; Deng, M.; Kuang, S. Polymeric nanoparticles functionalized with muscle-homing peptides for targeted delivery of phosphatase and tensin homolog inhibitor to skeletal muscle. Acta Biomaterialia, 2020, 118, 196–206. doi: 10.1016/j.actbio.2020.10.009
  39. Melentiev, P.N.; Son, L.V.; Kudryavtsev, D.S.; Kasheverov, I.E.; Tsetlin, V.I.; Esenaliev, R.O.; Balykin, V.I. Ultrafast, Ultrasensitive Detection and Imaging of Single Cardiac Troponin-T Molecules. ACS Sensors, 2020, 5(11), 3576–3583. doi: 10.1021/acssensors.0c01790
  40. Landry, M.R.; DuRoss, A.N.; Neufeld, M.J.; Hahn, L.; Sahay, G.; Luxenhofer, R.; Sun, C. Low Dose Novel PARP-PI3K Inhibition via Nanoformulation Improves Colorectal Cancer Immuno-Radiotherapy. Materials Today Bio, 2020, 8, 100082. doi: 10.1016/j.mtbio.2020.100082
  41. Gerosa, L.; Chidley, C.; Fröhlich, F.; Sanchez, G.; Lim, S.K.; Muhlich, J.; Chen, J.-Y.; Vallabhaneni, S.; Baker, G.J.; Schapiro, D.; Atanasova, M.I.; Chylek, L.A.; Shi, T.; Yi, L.; Nicora, C.D.; Claas, A.; Ng, T.S.C.; Kohler, R.H.; Lauffenburger, D.A.; Weissleder, R.; Miller, M.A.; Qian, W.-J.; Wiley, H.S.; Sorger, P.K. Receptor-Driven ERK Pulses Reconfigure MAPK Signaling and Enable Persistence of Drug-Adapted BRAF-Mutant Melanoma Cells. Cell Systems, 2020, 11(5), 478–494.e9. doi: 10.1016/j.cels.2020.10.002
  42. Jiang, Z.; He, H.; Liu, H.; Thayumanavan, S. Azide-Terminated RAFT Polymers for Biological Applications. Current Protocols in Chemical Biology, 2020, 12(4), e85. doi: 10.1002/cpch.85
  43. Dettling, S.E.; Ahmadi, M.; Lin, Z.; He, L.; Matthews, M.L. Discovery of Electrophiles and Profiling of Enzyme Cofactors. Current Protocols in Chemical Biology, 2020, 12(4), e86. doi: 10.1002/cpch.86
  44. Kim, S.M.; Park, J.; Kim, M.S.; Song, H.; Jo, A.; Park, H.; Kim, T.S.; Choi, S.H.; Park, S.B. Phenotypic Discovery of an Antivirulence Agent against Vibrio vulnificus via Modulation of Quorum-Sensing Regulator SmcR. ACS Infectious Diseases, 2020, 6(11), 3076–3082. doi: 10.1021/acsinfecdis.0c00587
  45. Vallmitjana, A.; Torrado, B.; Dvornikov, A.; Ranjit, S.; Gratton, E. Blind Resolution of Lifetime Components in Individual Pixels of Fluorescence Lifetime Images Using the Phasor Approach. Journal of Physical Chemistry B, 2020, 124(45), 10126–10137. doi: 10.1021/acs.jpcb.0c06946
  46. Covarrubias-Zambrano, O.; Shrestha, T.B.; Pyle, M.; Montes-Gonzalez, M.L.; Troyer, D.L.; Bossmann, S.H. Development of a gene delivery system composed of a cell penetrating peptide and a nontoxic polymer. ACS Applied Bio Materials, 2020, 3(11), 7418–7427. doi: 10.1021/acsabm.0c00561
  47. Hargrove, D.; Liang, B.; Kashfi-Sadabadi, R:; Joshi, G.N:; Gonzalez-Fajardo, L.; Glass, S.; Jay, M.; Salner, A.; Lu, X. Tumor-mesoporous silica nanoparticle interactions following intraperitoneal delivery for targeting peritoneal metastasis. Journal of Controlled Release, 2020, 328, 846–858. doi: 10.1016/j.jconrel.2020.11.003
  48. Li, W.; Suarato, G.; Cathcart, J.M.; Sargunas, P.R.; Meng, Y. Design, characterization, and intracellular trafficking of biofunctionalized chitosan nanomicelles. Biointerphases, 2020, 15, 061003. doi: 10.1116/6.0000380
  49. Catipovic, M.A.; Rapoport, T.A. Protease protection assays show polypeptide movement into the SecY channel by power strokes of the SecA ATPase. EMBO Reports, 2020, 21(11), e50905. doi: 10.15252/embr.202050905
  50. Binkley, M.; Cui, M.; Berezin, M.; Meacham, J.M. Antibody conjugate assembly on ultrasound-confined microcarrier particles. ACS Biomaterials Science & Engineering, 2020, 6(11), 6108–6116. doi: 10.1021/acsbiomaterials.0c01162
  51. Bobrin, V.A.; Lin, Y.; He, J.; Qi, Y.; Gu, W.; Monteiro, M.J. Therapeutic Delivery of Polymeric Tadpole Nanostructures with High Selectivity to Triple Negative Breast Cancer Cells. Biomacromolecules, 2020, 21(11), 4457–4468. doi: 10.1021/acs.biomac.0c00302
  52. Hong, K.; Song, D.; Jung, Y. Behavior control of membrane-less protein liquid condensates with metal ion-induced phase separation. Nature Communications, 2020, 11, 5554. doi: 10.1038/s41467-020-19391-8
  53. Jose, G.; Lu, Y.-J.; Hung, J.-T.; Yu, A.L.; Chen, J.-P. Co-Delivery of CPT-11 and Panobinostat with Anti-GD2 Antibody Conjugated Immunoliposomes for Targeted Combination Chemotherapy. Cancers, 2020, 12(11), 3211. doi: 10.3390/cancers12113211
  54. Iurova, E.; Beloblov, I.; Beloborodov, E.; Rastorgueva, E.; Pogodina, E.; Tazintseva, E.; Saenko, Y.; Fomin, A. Use of Natural Peptides with a Cysteine Knot of Arthropods as a Carrier of a Peptide Tropic to Glutamate Carboxypeptidase II. Systematic Reviews in Pharmacy, 2020, 11(9), 503–509. doi: 10.31838/srp.2020.9.73
  55. Ruano-Salguero, J.S.; Lee, K.H. Adsorptive-mediated endocytosis of Sulfo-Cy5-labeled IgG causes aberrant IgG processing by brain endothelial-like cells. Molecular Pharmaceutics, 2020, 17(11), 4280–4285. doi: 10.1021/acs.molpharmaceut.0c00712
  56. Shipunova, V.O.; Komedchikova, E.N.; Kotelnikova, P.A.; Zelepukin, I.V.; Schulga, A.A.; Proshkina, G.M.; Shramova, E.I.; Kutscher, H.L.; Telegin, G.B.; Kabashin, A.V.; Prasad, P.N.; Deyev, S.M. Dual Regioselective Targeting the Same Receptor in Nanoparticle-Mediated Combination Immuno/Chemotherapy for Enhanced Image-Guided Cancer Treatment. ACS Nano, 2020, 14(10), 12781–12795. doi: 10.1021/acsnano.0c03421
  57. Ghimire, C.; Wang, H.; Li, H.; Vieweger, M.; Xu, C.; Guo, P. RNA Nanoparticles as Rubber for Compelling Vessel Extravasation to Enhance Tumor Targeting and for Fast Renal Excretion to Reduce Toxicity. ACS Nano, 2020, 14(10), 13180–13191. doi: 10.1021/acsnano.0c04863
  58. Sokolova, V.; Mekky, G.; van der Meer, S.B.; Seeds, M.C.; Atala, A.J.; Epple, M. Transport of ultrasmall gold nanoparticles (2 nm) across the blood-brain barrier in a six-cell brain spheroid model. Scientific Reports, 2020, 10, 18033. doi: 10.1038/s41598-020-75125-2
  59. Álamo, P.; Pallarès, V.; Céspedes, M.; Falgàs, A.; Sanchez, J.M.; Serna, N.; Sánchez-García, L.; Voltà-Duràn, E.; Morris, G.A.; Sánchez-Chardi, A.; Casanova, I.; Mangues, R.; Vazquez, E.; Villaverde, A.; Unzueta, U. Fluorescent Dye Labeling Changes the Biodistribution of Tumor-Targeted Nanoparticles. Pharmaceutics, 2020, 12(11), 1004. doi: 10.3390/pharmaceutics12111004
  60. Vervoort, D.F.M.; Pretto, C.; van Hest, J.C.M. Insight into N-terminal localization and dynamics of engineered virus-like particles. RSC Advances, 2020, 10(64), 38774–38781. doi: 10.1039/D0RA07612K
  61. Wilder, L.M. Handali, P.R.; Webb, L.J.; Crooks, R.M. Interactions between Oligoethylene Glycol-Capped AuNPs and Attached Peptides Control Peptide Structure. Bioconjugate Chemistry, 2020, 31(10), 2383–2391. doi: 10.1021/acs.bioconjchem.0c00447
  62. Shramova, E.; Proshkina, G.; Shipunova, V.; Ryabova, A.; Kamyshinsky, R.; Konevega, A.; Schulga, A.; Konovalova, E.; Telegin, G.; Deyev, S. Dual Targeting of Cancer Cells with DARPin-Based Toxins for Overcoming Tumor Escape. Cancers, 2020, 12(10), 3014. doi: 10.3390/cancers12103014
  63. Saito, E.; Gurczynski, S.J.; Kramer, K.R.; Wilke, C.A.; Miller, S.D.; Moore, B.B.; Shea, L.D. Modulating lung immune cells by pulmonary delivery of antigen-specific nanoparticles to treat autoimmune disease. Science Advances, 2020, 6(42), eabc9317. doi: 10.1126/sciadv.abc9317
  64. McCrorie, P.; Mistry, J.; Taresco, V.; Lovato, T.; Fay, M.; Ward, I.; Ritchie, A.A.; Clarke, P.A.; Smith, S.J.; Marlow, M.; Rahman, R. Etoposide and olaparib polymer-coated nanoparticles within a bioadhesive sprayable hydrogel for post-surgical localised delivery to brain tumours. European Journal of Pharmaceutics and Biopharmaceutics, 2020, 157, 108–120. doi: 10.1016/j.ejpb.2020.10.005
  65. Choi, Y.; Han, H.; Jeon, S.; Yoon, H.Y.; Kim, H.; Kwon, I.C.; Kim, K. Deep Tumor Penetration of Doxorubicin-Loaded Glycol Chitosan Nanoparticles Using High-Intensity Focused Ultrasound. Pharmaceutics, 2020, 12(10), 974. doi: 10.3390/pharmaceutics12100974
  66. Zahnreich, S.; Weber, B.; Rösch, G.; Schindler, D.; Schmidberger, H. Compromised repair of radiation-induced DNA double-strand breaks in Fanconi anemia fibroblasts in G2. DNA Repair, 2020, 96, 102992. doi: 10.1016/j.dnarep.2020.102992
  67. Zhang, M.; Zhou, L.; Xu, Y.; Yang, M.; Xu, Y.; Komaniecki, G.P.; Kosciuk, T.; Chen, X.; Lu, X.; Zou, X.; Linder, M.E.; Lin, H. A STAT3 palmitoylation cycle promotes TH17 differentiation and colitis. Nature, 2020, 586(7829), 434–439. doi: 10.1038/s41586-020-2799-2
  68. Chen, J.; Guo, Y.; Li, H.; Zhang, C.; Chang, X.; Ma, R.; Cheng, H.; Ye, X.; Cui, H.; Li, Y. Near-infrared dye-labeled antibody COC183B2 enables detection of tiny metastatic ovarian cancer and optimizes fluorescence-guided surgery. Journal of Surgical Oncology, 2020, 122(6), 1207–1217. doi: 10.1002/jso.26130
  69. Agote-Aran, A.; Schmucker, S.; Jerabkova, K.; Jmel Boyer, I.; Berto, A.; Pacini, L.; Ronchi, P.; Kleiss, C.; Guerard, L.; Schwab, Y.; Moine, H.; Mandel, J.-L.; Jacquemont, S.; Bagni, C.; Sumara, I. Spatial control of nucleoporin condensation by fragile X-related proteins. EMBO Journal, 2020, 39(20), e104467. doi: 10.15252/embj.2020104467
  70. Hortelão, Ana C. and García-Jimeno, S.; Cano-Sarabia, M.; Patiño, T.; Maspoch, D.; Sanchez, S. LipoBots: Using Liposomal Vesicles as Protective Shell of Urease-Based Nanomotors. Advanced Functional Materials, 2020, 30(42), 2002767. doi: 10.1002/adfm.202002767
  71. Zhang, W.; Teske, N.; Samadi, M.; Sarem, M.; Shastri, V.P. Unraveling the role of β1 integrin isoforms in cRGD-mediated uptake of nanoparticles bearing hydrophilized alkyne moieties in epithelial and endothelial cells. Acta Biomaterialia, 2020, 116, 344–355. doi: 10.1016/j.actbio.2020.08.038
  72. Hifni, B.; Khan, M.; Devereux, S.J.; Byrne, M.H.; Quinn, S.J.; Simpson, J.C. Investigation of the cellular destination of fluorescently labelled carbon nanohorns in cultured cells. ACS Applied Bio Materials, 2020, 3(10), 6790–6801. doi: 10.1021/acsabm.0c00748
  73. Park, H.; Gladstone, M.; Shanley, C.; Goodrich, R.; Guth, A. A novel cancer immunotherapy utilizing autologous tumour tissue. Vox Sanguinis, 2020, 115(6), 525–535. doi: 10.1111/vox.12935
  74. Kovacs, L.; Cabral, P.; Chammas, R. Mannose receptor 1 expression does not determine the uptake of high-density mannose dendrimers by activated macrophages populations. PloS One, 2020, 15(10), e0240455. doi: 10.1371/journal.pone.0240455
  75. Kang, J.; Lhee, S.; Lee, J.K.; Zare, R.N.; Nam, H.G. Restricted intramolecular rotation of fluorescent molecular rotors at the periphery of aqueous microdroplets in oil. Scientific Reports, 2020, 10, 16859. doi: 10.1038/s41598-020-73980-7
  76. van der Linden, C.J.; Gupta, P.; Bhuiya, A.I.; Riddick, K.R.; Hossain, K.; Santoro, S.W. Olfactory Stimulation Regulates the Birth of Neurons That Express Specific Odorant Receptors. Cell Reports, 2020, 33(1), 108210. doi: 10.1016/j.celrep.2020.108210
  77. Lee, J.; Kim, J.-H.; You, D.G.; Kim, S.; Um, W.; Jeon, J.; Kim, C.H.; Joo, H.; Yi, G.-R.; Park, J.H. Cavitation-Inducible Mesoporous Silica-Titania Nanoparticles for Cancer Sonotheranostics. Advanced Healthcare Materials, 2020, 9(19), 2000877. doi: 10.1002/adhm.202000877
  78. Islam, M.R.; Nguy, C.; Pandit, S.; Lyon, L.A. Design and Synthesis of Core–Shell Microgels with One‐Step Clickable Crosslinked Cores and Ultralow Crosslinked Shells. Macromolecular Chemistry and Physics, 2020, 221(19), 2000156. doi: 10.1002/macp.202000156
  79. Yang, S.W.; Huang, X.; Lin, W.; Min, J.; Miller, D.J.; Mayasundari, A.; Rodrigues, P.; Griffith, E.C.; Gee, C.T.; Li, L.; Li, W.; Lee, R.E.; Rankovic, Z.; Chen, T.; Potts, P.R. Structural basis for substrate recognition and chemical inhibition of oncogenic MAGE ubiquitin ligases. Nature Communications, 2020, 11, 4931. doi: 10.1038/s41467-020-18708-x
  80. Zeng, Y.; Wang, J.; Wang, Z.; Chen, G.; Yu, J.; Li, S.; Li, Q.; Li, H.; Wen, D.; Gu, Z.; Gu, Z. Colloidal crystal microneedle patch for glucose monitoring. Nano Today, 2020, 35, 100984. doi: 10.1016/j.nantod.2020.100984
  81. Li, H.-Y.; Lin, H.-C.; Huang, B.-J.; Lo, A.Z.K.; Saidin, S.; Lai, C.-H. Size Preferences Uptake of Glyco-Silica Nanoparticles to MDA-MB-231 Cell. Langmuir, 2020, 36(38), 11374–11382. doi: 10.1021/acs.langmuir.0c02297
  82. Shuvalova, M.L.; Kopylov, A.T.; Mazurov, D.V.; Pichugin, A.V.; Bovin, N.V.; Filatov, A.V. CD44-Associated Tn Antigen as a New Biomarkerof Tumor Cells with Aberrant Glycosylation. Biochemistry (Moscow), 2020, 85(9), 1064–1071. doi: 10.1134/S0006297920090060
  83. Long, M.; Lu, A.; Lu, M.; Weng, L.; Chen, Q.; Zhu, L.; Chen, Z. Azo-inserted responsive hybrid liposomes for hypoxia-specific drug delivery. Acta Biomaterialia, 2020, 115, 343–357. doi: 10.1016/j.actbio.2020.07.061
  84. Phung, C.D.; Pham, T.T.; Nguyen, H.T.; Nguyen, T.T.; Ou, W.; Jeong, J.-H.; Choi, H.-G.; Ku, S.K.; Yong, C.S.; Kim, J.O. Anti-CTLA-4 Antibody-Functionalized Dendritic Cell-derived Exosomes Targeting Tumor-draining Lymph Nodes for Effective Induction of Antitumor T-cell Responses. Acta Biomaterialia, 2020, 115, 371–382. doi: 10.1016/j.actbio.2020.08.008
  85. Liu, H.-J.; Wang, M.; Hu, X.; Shi, S.; Xu, P. Enhanced Photothermal Therapy through the In Situ Activation of a Temperature and Redox Dual-Sensitive Nanoreservoir of Triptolide. Small, 2020, 16(38), e2003398. doi: 10.1002/smll.202003398
  86. Huang, Y.; Jiang, K.; Zhang, X.; Chung, E.J. The Effect of Size, Charge, and Peptide Ligand Length on Kidney Targeting by Small, Organic Nanoparticles. Bioengineering & Translational Medicine, 2020, 5(3), e10173. doi: 10.1002/btm2.10173
  87. Liu, M.; Apriceno, A.; Sipin, M.; Scarpa, E.; Rodriguez-Arco, L.; Poma, A.; Marchello, G.; Battaglia, G.; Angioletti-Uberti, S. Combinatorial entropy behaviour leads to range selective binding in ligand-receptor interactions. Nature Communications, 2020, 11, 4836. doi: 10.1038/s41467-020-18603-5
  88. Pfister, J.; Lichius, A.; Summer, D.; Haas, H.; Kanagasundaram, T.; Kopka, K.; Decristoforo, C. Live-cell imaging with Aspergillus fumigatus-specific fluorescent siderophore conjugates. Scientific Reports, 2020, 10, 15519. doi: 10.1038/s41598-020-72452-2
  89. Reshitko, G.S.; Yamansarov, E.Y.; Evteev, S.A.; Lopatukhina, E.V.; Shkil', D.O.; Saltykova, I.V.; Lopukhov, A.V.; Kovalev, S.V.; Lobov, A.N.; Kislyakov, I.V.; Burenina, O.Y.; Klyachko, N.L.; Garanina, A.S.; Dontsova, O.A.; Ivanenkov, Y.A.; Erofeev, A.S.; Gorelkin, P.V.; Beloglazkina, E.K.; Majouga, A.G. Synthesis and Evaluation of New Trivalent Ligands for Hepatocyte Targeting via the Asialoglycoprotein Receptor. Bioconjugate Chemistry, 2020, 31(5), 1313–1319. doi: 10.1021/acs.bioconjchem.0c00202
  90. Oh, S.; Boo, K.; Kim, J.; Baek, S.A.; Jeon, Y.; You, J.; Lee, H.; Choi, H.-J.; Park, D.; Lee, J.M.; Baek, S.H. The chromatin-binding protein PHF6 functions as an E3 ubiquitin ligase of H2BK120 via H2BK12Ac recognition for activation of trophectodermal genes. Nucleic Acids Research, 2020, 48(16), 9037–9052. doi: 10.1093/nar/gkaa626
  91. Teng, Y.; Liang, H.; Zhang, Z.; He, Y.; Pan, Y.; Yuan, S.; Wu, X.; Zhao, Q.; Yang, H.; Zhou, P. Biodistribution and immunomodulatory activities of a proteoglycan isolated from Ganoderma lucidum. Journal of Functional Foods, 2020, 74, 104193. doi: 10.1016/j.jff.2020.104193
  92. Susnik, E.; Taladriz-Blanco, P.; Drasler, B.; Balog, S.; Petri-Fink, A.; Rothen-Rutishauser, B. Increased Uptake of Silica Nanoparticles in Inflamed Macrophages but Not upon Co-Exposure to Micron-Sized Particles. Cells, 2020, 9(9), 2099. doi: 10.3390/cells9092099
  93. Hossian, A.K.M.N.; Jois, S.D.; Jonnalagadda, S.C.; Mattheolabakis, G. Nucleic Acid Delivery with α-Tocopherol-Polyethyleneimine-Polyethylene Glycol Nanocarrier System. International Journal of Nanomedicine, 2020, 15, 6689–6703. doi: 10.2147/IJN.S259724
  94. Tugel, U.; Casas, M.G.; Wiltschi, B. Site-Specific Incorporation of Non-canonical Amino Acids by Amber Stop Codon Suppression in Escherichia coli. Peptide and Protein Engineering (Springer Protocols Handbooks), 2020, 267–281. doi: 10.1007/978-1-0716-0720-6_14
  95. Peplau, E.; De Rose, F.; Reder, S.; Mittelhaeuser, M.; Scafetta, G.; Schwaiger, M.; Weber, W.A.; Bartolazzi, A.; Skerra, A.; D'Alessandria, C. Development of a chimeric Fab directed against human galectin-3 and validation as an immune-PET tracer for the sensitive in vivo imaging of thyroid cancer. Thyroid, 2020, 30(9), 1314–1326. doi: 10.1089/thy.2019.0670
  96. Yuan, M.; Chen, X.; Sun, Y.; Jiang, L.; Xia, Z:; Ye, K.; Jiang, H.; Yang, B.; Ying, M.; Cao, J.; He, Q. ZDHHC12-mediated claudin-3 S-palmitoylation determines ovarian cancer progression. Acta Pharmaceutica Sinica B, 2020, 10(8), 1426–1439. doi: 10.1016/j.apsb.2020.03.008
  97. Honda, Y.; Nomoto, T.; Matsui, M.; Takemoto, H.; Kaihara, Y.; Miura, Y.; Nishiyama, N. Sequential Self-Assembly Using Tannic Acid and Phenylboronic Acid-Modified Copolymers for Potential Protein Delivery. Biomacromolecules, 2020, 21(9), 3826–3835. doi: 10.1021/acs.biomac.0c00903
  98. Desai, B.J.; Gonzalez, R.L. Multiplexed genomic encoding of non-canonical amino acids for labeling large complexes. Nature Chemical Biology, 2020, 16, 1129–1135. doi: 10.1038/s41589-020-0599-5
  99. Kim, D.; Lee, S.S.; Yoo, W.Y.; Moon, H.; Cho, A.; Park, S.Y.; Kim, Y.-S.; Kim, H.R.; Lee, H.J. Combination Therapy with Doxorubicin-Loaded Reduced Albumin Nanoparticles and Focused Ultrasound in Mouse Breast Cancer Xenografts. Pharmaceuticals, 2020, 13(9), 235. doi: 10.3390/ph13090235
  100. FitzGerald, L.I.; Aurelio, L.; Chen, M.; Yuen, D.; Rennick, J.J.; Graham, B.; Johnston, A.P.R. A molecular sensor to quantify the localization of proteins, DNA and nanoparticles in cells. Nature Communications, 2020, 11(1), 4482. doi: 10.1038/s41467-020-18082-8
  101. Tischer, D.; Weiner, O. Optogenetic Tuning of Protein-protein Binding in Bilayers Using LOVTRAP. Bio-protocol, 2020, 10(17), e3745. doi: 10.21769/BioProtoc.3745
  102. Xie, H.; Zhu, H.; Zhou, K.; Wan, J.; Zhang, L.; Yang, Z.; Zhou, L.; Chen, X.; Xu, X.; Zheng, S.; Wang, H. Target-oriented delivery of self-assembled immunosuppressant cocktails prolongs allogeneic orthotopic liver transplant survival. Journal of Controlled Release, 2020, 328, 237–250. doi: 10.1016/j.jconrel.2020.08.043
  103. Carreras-Badosa, G.; Maslovskaja, J.; Periyasamy, K.; Urgard, E.; Padari, K.; Vaher, H.; Tserel, L.; Gestin, M.; Kisand, K.; Arukuusk, P.; Lou, C.; Langel, Ü.; Wengel, J.; Pooga, M.; Rebane, A. NickFect type of cell-penetrating peptides present enhanced efficiency for microRNA-146a delivery into dendritic cells and during skin inflammation. Biomaterials, 2020, 262, 120316. doi: 10.1016/j.biomaterials.2020.120316
  104. Benslimane, Y.; Bertomeu, T.; Coulombe-Huntington, J.; McQuaid, M.; Sánchez-Osuna, M.; Papadopoli, D.; Avizonis, D.; De Sa Tavares Russo, M.; Huard, C.; Topisirovic, I.; Wurtele, H.; Tyers, M.; Harrington, L. Genome-Wide Screens Reveal that Resveratrol Induces Replicative Stress in Human Cells. Molecular Cell, 2020, 79(5), 846–856. doi: 10.1016/j.molcel.2020.07.010
  105. Teng, F.; Wu, X.; Libera, M.R. Chemical Orthogonality in Surface-Patterned Poly(ethylene glycol) Microgels. Langmuir, 2020, 36(35), 10622–10627. doi: 10.1021/acs.langmuir.0c02172
  106. Furubayashi, T.; Ishida, K.; Nakata, E.; Morii, T.; Naruse, K.; Matsushita, M.; Fujiyoshi, S. Cryogenic Far-Field Fluorescence Nanoscopy: Evaluation with DNA Origami. Journal of Physical Chemistry B, 2020, 124(35), 7525–7536. doi: 10.1021/acs.jpcb.0c04721
  107. Cassidy, J.; Ellison, C.; Bettinger, J.; Yang, M.; Moroz, P.; Zamkov, M. Enabling Narrow Emission Linewidths in Colloidal Nanocrystals through Coalescence Growth. Chemistry of Materials, 2020, 32(17), 7524–7534. doi: 10.1021/acs.chemmater.0c02874
  108. Wang, C.; Guan, W.; Chen, R.; Levi-Kalisman, Y.; Xu, Y.; Zhang, L.; Zhou, M.; Xu, G.; Dou, H. Fluorescent glycan nanoparticle-based FACS assays for the identification of genuine drug-resistant cancer cells with differentiation potential. Nano Research, 2020, 13(11), 3110–3122. doi: 10.1007/s12274-020-2981-8
  109. Perkins, L.A.; Nyiranshuti, L.; Little-Ihrig, L.; Latoche, J.D.; Day, K.E.; Zhu, Q.; Tavakoli, S.; Sundd, P.; Novelli, E.M.; Anderson, C.J. Integrin VLA-4 as a PET imaging biomarker of hyper-adhesion in transgenic sickle mice. Blood Advances, 2020, 4(17), 4102–4112. doi: 10.1182/bloodadvances.2020002642
  110. Sim, T.; Lim, C.; Hoang, N.H.; Shin, Y.; Kim, J.C.; Park, J.Y.; Her, J.; Lee, E.S.; Youn, Y.S.; Oh, K.T. An On-Demand pH-Sensitive Nanocluster for Cancer Treatment by Combining Photothermal Therapy and Chemotherapy. Pharmaceutics, 2020, 12, 839. doi: 10.3390/pharmaceutics12090839
  111. Tamošiūnė, I.; Gelvonauskienė, D.; Haimi, P.; Mildažienė, V.; Koga, K.; Shiratani, M.; Baniulis, D. Cold Plasma Treatment of Sunflower Seeds Modulates Plant-Associated Microbiome and Stimulates Root and Lateral Organ Growth. Frontiers in Plant Science, 2020, 11, 568924. doi: 10.3389/fpls.2020.568924
  112. Valadares, R.B.S.; Perotto, S.; Lucheta, A.R.; Santos, E.C.; Oliveira, R.M.; Lambais, M.R. Proteomic and Transcriptomic Analyses Indicate Metabolic Changes and Reduced Defense Responses in Mycorrhizal Roots of Oeceoclades maculata (Orchidaceae) Collected in Nature. Journal of Fungi, 2020, 6(3), 148. doi: 10.3390/jof6030148
  113. Sapozhnikova, Y.P.; Koroleva, A.G.; Yakhnenko, V.M.; Tyagun, M.L.; Glyzina, O.Y.; Coffin, A.B.; Makarov, M.M.; Shagun, A.N.; Kulikov, V.A.; Gasarov, P.V.; Kirilchik, S.V.; Klimenkov, I.V.; Sudakov, N.P.; Anoshko, P.N.; Kurashova, N.A.; Sukhanova, L.V. Molecular and cellular responses to long-term sound exposure in peled (Coregonus peled). Journal of the Acoustical Society of America, 2020, 148(2), 895–907. doi: 10.1121/10.0001674
  114. Babity, S.; Polomska, A.K.; Couture, F.; Bonmarin, M.; Fehr, D.; Detmar, M.; Brambilla, D. Rational design of a fluorescent microneedle tattoo for minimally invasive monitoring of lymphatic function. Journal of Controlled Release, 2020, 327, 350–359. doi: 10.1016/j.jconrel.2020.08.017
  115. Thompson, T.A.; Touré, M.B.; Sanogo, D.; Shaffer, J.G.; Doumbia, S.O.; Krogstad, D.J. Template copy number and the sensitivity of quantitative PCR for Plasmodium falciparum in asymptomatic individuals. Malaria Journal, 2020, 19, 295. doi: 10.1186/s12936-020-03365-8
  116. Park, B.G.; Kim, Y.J.; Min, J.H.; Cheong, T.-C.; Nam, S.H.; Cho, N.-H.; Kim, Y.K.; Lee, K.B. Assessment of Cellular Uptake Efficiency According to Multiple Inhibitors of Fe3O4-Au Core-Shell Nanoparticles: Possibility to Control Specific Endocytosis in Colorectal Cancer Cells. Nanoscale Research Letters, 2020, 15, 165. doi: 10.1186/s11671-020-03395-w
  117. Vu, M.N.; Kelly, H.G.; Wheatley, A.K.; Peng, S.; Pilkington, E.H.; Veldhuis, N.A.; Davis, T.P.; Kent, S.J.; Truong, N.P. Cellular Interactions of Liposomes and PISA Nanoparticles during Human Blood Flow in a Microvascular Network. Small, 2020, 16(33), e2002861. doi: 10.1002/smll.202002861
  118. Un Kim, J.; Muhammad Shahbaz, H.; Lee, H.; Kim, T.; Yang, K.; Hoon Roh, Y.; Park, J. Optimization of Phytic acid-crosslinked Chitosan Microspheres for Oral Insulin Delivery Using Responsive Surface Methodology. International Journal of Pharmaceutics, 2020, 588, 119736. doi: 10.1016/j.ijpharm.2020.119736
  119. Locke, L.; Shankaran, K.; Gong, L.; Stoodley, P.; Vozar, S.L.; Cole, S.L.; Tweedle, M.F.; Wozniak, D.J. Evaluation of peptide-based probes towards in vivo diagnostic imaging of bacterial biofilm-associated infections. ACS Infectious Diseases, 2020, 6(8), 2086–2098. doi: 10.1021/acsinfecdis.0c00125
  120. Garafutdinov, R.R.; Gilvanov, A.R.; Kupova, O.Y.; Sakhabutdinova, A.R. Effect of metal ions on isothermal amplification with Bst exo- DNA polymerase. International Journal of Biological Macromolecules, 2020, 161, 1447–1455. doi: 10.1016/j.ijbiomac.2020.08.028
  121. Zaw Thin, M.; Allan, H.; Bofinger, R.; Kostelec, T.D.; Guillaume, S.; Connell, J.J.; Patrick, P.S.; Hailes, H.C.; Tabor, A.B.; Lythgoe, M.F.; Stuckey, D.J.; Kalber, T.L. Multi-modal imaging probe for assessing the efficiency of stem cell delivery to orthotopic breast tumours. Nanoscale, 2020, 12(31), 16570–16585. doi: 10.1039/d0nr03237a
  122. Ramey-Ward, A.N.; Su, H.; Salaita, K. Mechanical stimulation of adhesion receptors using light-responsive nanoparticle actuators enhances myogenesis. ACS Applied Materials & Interfaces, 2020, 12(32), 35903–35917. doi: 10.1021/acsami.0c08871
  123. Mahmoud, A.M.; Morrow, J.P.; Pizzi, D.; Azizah, A.M.; Davis, T.P.; Tabor, R.F.; Kempe, K. Tuning Cellular Interactions of Carboxylic Acid Side Chain Containing Polyacrylates: The Role of Cyanine Dye Label and Side Chain Type. Biomacromolecules, 2020, 21(8), 3007–3016. doi: 10.1021/acs.biomac.0c00244
  124. Yen, H.-C.; Kuo, T.-R.; Huang, M.-H.; Huang, H.-K.; Chen, C.-C. Design of Fluorescence-Enhanced Silver Nanoisland Chips for High-Throughput and Rapid Arsenite Assay. ACS Omega, 2020, 5(31), 19771–19777. doi: 10.1021/acsomega.0c02533
  125. Grätz, L.; Tropmann, K.; Bresinsky, M.; Müller, C.; Bernhardt, G.; Pockes, S. NanoBRET binding assay for histamine H2 receptor ligands using live recombinant HEK293T cells. Scientific Reports, 2020, 10, 13288. doi: 10.1038/s41598-020-70332-3
  126. Paul, M.; Tscheuschner, G.; Herrmann, S.; Weller, M.G. Fast Detection of 2,4,6-Trinitrotoluene (TNT) at ppt Level by a Laser-Induced Immunofluorometric Biosensor. Biosensors, 2020, 10(8), 89. doi: 10.3390/bios10080089
  127. Lix, K.; Krause, K.D.; Kim, H.; Algar, W.R. Investigation of the Energy Transfer Mechanism Between Semiconducting Polymer Dots and Organic Dyes. Journal of Physical Chemistry C, 2020, 124(31), 17387–17400. doi: 10.1021/acs.jpcc.0c04983
  128. Than, A.; Duong, P.K.; Zan, P.; Liu, J.; Leow, M.K.-S.; Chen, P. Lancing Drug Reservoirs into Subcutaneous Fat to Combat Obesity and Associated Metabolic Diseases. Small, 2020, 16(31), e2002872. doi: 10.1002/smll.202002872
  129. Warminski, M.; Kowalska, J.; Jemielity, J. Solid-Phase Synthesis of RNA 5'-Azides and Their Application for Labeling, Ligation, and Cyclization Via Click Chemistry. Current Protocols in Nucleic Acid Chemistry, 2020, 82(1), e112. doi: 10.1002/cpnc.112
  130. Hilger, D.; Kumar, K.K.; Hu, H.; Pedersen, M.F.; O'Brien, E.S.; Giehm, L.; Jennings, C.; Eskici, G.; Inoue, A.; Lerch, M.; Mathiesen, J.M.; Skiniotis, G.; Kobilka, B.K. Structural insights into differences in G protein activation by family A and family B GPCRs. Science, 2020, 369, eaba3373. doi: 10.1126/science.aba3373
  131. Keil, J.M.; Doyle, D.Z.; Qalieh, A.; Lam, M.M.; Funk, O.H.; Qalieh, Y.; Shi, L.; Mohan, N.; Sorel, A.; Kwan, K.Y. Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80. Nature Communications, 2020, 11, 3839. doi: 10.1038/s41467-020-17551-4
  132. Sakhabutdinova, A.R.; Chemeris, A.V.; Garafutdinov, R.R. Enhancement of PCR efficiency using mono- and disaccharides. Analytical Biochemistry, 2020, 606, 113858. doi: 10.1016/j.ab.2020.113858
  133. Liu, L.; Xu, Y.; Zhang, P.; You, J.; Li, W.; Chen, Y.; Li, R.; Rui, B.; Dou, H. High-order Assembly Towards Polysaccharide-Based Complex Coacervate Nanodroplets Capable of Targeting Cancer Cells. Langmuir, 2020, 36(29), 8580–8588. doi: 10.1021/acs.langmuir.0c01458
  134. Chen, X.; Xu, J.; Wong, N.-K.; Zhong, S.; Yang, M.; Liu, Z.; Lu, Y.; Li, W.; Zhou, Y. Chemoproteomic profiling of cobalamin-independent methionine synthases in plant with a covalent probe. Journal of Agricultural and Food Chemistry, 2020, 68(30), 8050–8056. doi: 10.1021/acs.jafc.0c03301
  135. Wang, Y.; Li, L.; Ma, Y.; Tang, Y.; Zhao, Y.; Li, Z.; Pu, W.; Huang, B.; Wen, X.; Cao, X.; Chen, J.; Chen, W.; Zhou, Y.; Zhang, J. A Multifunctional Supramolecular Hydrogel for Prevention of Epidural Adhesion after Laminectomy. ACS Nano, 2020, 14(7), 8202–8219. doi: 10.1021/acsnano.0c01658
  136. Sanman, L.E.; Chen, I.W.; Bieber, J.M.; Thorne, C.A.; Wu, L.F.; Altschuler, S.J. Generation and Quantitative Imaging of Enteroid Monolayers. Methods in Molecular Biology, 2020, 2171, 99–113. doi: 10.1007/978-1-0716-0747-3_6
  137. Lee, S.H.; Park, D.J.; Yun, W.S.; Park, J.-E.; Choi, J.S.; Key, J.; Seo, Y.J. Endocytic trafficking of polymeric clustered superparamagnetic iron oxide nanoparticles in mesenchymal stem cells. Journal of Controlled Release, 2020, 326, 408–418. doi: 10.1016/j.jconrel.2020.07.032
  138. Göbel, M.W.; Bolz, M.; Thomas, L.; Scheffer, U.; Kalden, E.; Hartmann, R.K. Redirection of miRNA-Argonaute Complexes to Specific Target Sites by Synthetic Adaptor Molecules. Chemistry & Biodiversity, 2020, 17(7), e2000272. doi: 10.1002/cbdv.202000272
  139. Gruber, C.G.; Pegoli, A.; Müller, C.; Grätz, L.; She, X.; Keller, M. Differently fluorescence-labelled dibenzodiazepinone-type muscarinic acetylcholine receptor ligands with high M2R affinity. RSC Medicinal Chemistry, 2020, 11(7), 823–832. doi: 10.1039/D0MD00137F
  140. Lim, Y.G.; Kim, H.J.; Kim, J.W.; Park, K. Calcium-binding near-infrared fluorescent nanoprobe for bone tissue imaging. Journal of Industrial and Engineering Chemistry, 2020, 89, 442–447. doi: 10.1016/j.jiec.2020.06.018
  141. Kocere, A.; Resseguier, J.; Wohlmann, J.; Skjeldal, F.M.; Khan, S.; Speth, M.; Dal, N.-J.K.; Ng, M.Y.W.; Alonso-Rodriguez, N.; Scarpa, E.; Rizzello, L.; Battaglia, G.; Griffiths, G.; Fenaroli, F. Real-time imaging of polymersome nanoparticles in zebrafish embryos engrafted with melanoma cancer cells: Localization, toxicity and treatment analysis. EBioMedicine, 2020, 58, 102902. doi: 10.1016/j.ebiom.2020.102902
  142. Shukla, Sourabh and Roe, Anne Jessica and Liu, Ruifu and Veliz, Frank A. and Commandeur, Ulrich and Wald, David N. and Steinmetz, Nicole F. Affinity of plant viral nanoparticle potato virus X (PVX) towards malignant B cells enables cancer drug delivery. Biomaterials Science, 2020, 8(14), 3935–3943. doi: 10.1039/D0BM00683A
  143. Haddad, Y.; Charousova, M.; Zivotska, H.; Splichal, Z.; Merlos Rodrigo, M.A.; Michalkova, H.; Krizkova, S.; Tesarova, B.; Richtera, L.; Vitek, P.; Stokowa-Soltys, K.; Hynek, D.; Milosavljevic, V.; Rex, S.; Heger, Z. Norepinephrine transporter-derived homing peptides enable rapid endocytosis of drug delivery nanovehicles into neuroblastoma cells. Journal of Nanobiotechnology, 2020, 18, 95. doi: 10.1186/s12951-020-00654-x
  144. Yang, J.; Wang, T.; Zhao, L.; Rajasekhar, V.K.; Joshi, S.; Andreou, C.; Pal, S.; Hsu, H.-T.; Zhang, H.; Cohen, I.J.; Huang, R.; Hendrickson, R.C.; Miele, M.M.; Pei, W.; Brendel, M.B.; Healey, J.H.; Chiosis, G.; Kircher, M.F. Gold/alpha-lactalbumin nanoprobes for the imaging and treatment of breast cancer. Nature Biomedical Engineering, 2020, 4, 686–703. doi: 10.1038/s41551-020-0584-z
  145. Martínez-Jothar, L.; Barendrecht, A.D.; de Graaff, A.M.; Oliveira, S.; van Nostrum, C.F.; Schiffelers, R.M.; Hennink, W.E.; Fens, M.H.A.M. Endothelial Cell Targeting by cRGD-Functionalized Polymeric Nanoparticles under Static and Flow Conditions. Nanomaterials, 2020, 10(7), 1353. doi: 10.3390/nano10071353
  146. Zhou, Y.; Zhu, X.; Lin, S.; Zhu, C.; Wu, L.; Chen, R.; Chen, Z.; Li, W. A Novel Nanoparticle Preparation to Enhance the Gastric Adhesion and Bioavailability of Xanthatin. International Journal of Nanomedicine, 2020, 15, 5073–5082. doi: 10.2147/IJN.S252049
  147. Martín-Moreno, A.; Jiménez Blanco, J.L.; Mosher, J.; Swanson, D.R.; García Fernández, J.M.; and Sharma, A.; Ceña, V.; Muñoz-Fernández, M.A. Nanoparticle-Delivered HIV Peptides to Dendritic Cells a Promising Approach to Generate a Therapeutic Vaccine. Pharmaceutics, 2020, 12(7), 656. doi: 10.3390/pharmaceutics12070656
  148. Chetverikov, P.E.; Cvrković, T.; Efimov, P.G.; Klimov, P.B.; Petanović, R.U.; Romanovich, A.E.; Schubert, M.A.; Sukhareva, S.I.; Zukoff, S.N.; Amrine, J. Molecular phylogenetic analyses reveal a deep dichotomy in the conifer-inhabiting genus Trisetacus (Eriophyoidea: Nalepellidae), with the two lineages differing in their female genital morphology and host associations. Experimental and Applied Acarology, 2020, 81(3), 287–316. doi: 10.1007/s10493-020-00503-4
  149. Chen, K.; Yang, R.; Li, Y.; Zhou, J.C.; Zhang, M. Giant ankyrin-B suppresses stochastic collateral axon branching through direct interaction with microtubules. Journal of Cell Biology, 2020, 219(8), e201910053. doi: 10.1083/jcb.201910053
  150. Zhang, N.; Shi, S.; Yoo, B.; Yuan, X.; Li, W.; Zhang, S. 2D-HELS MS Seq: A General LC-MS-Based Method for Direct and de novo Sequencing of RNA Mixtures with Different Nucleotide Modifications. Journal of Visualized Experiments, 2020, e61281. doi: 10.3791/61281
  151. Kim, S.; Kang, S.H.; Byun, S.H.; Kim, H.-J.; Park, I.-K.; Hirschberg, H.; Hong, S.J. Intercellular Bioimaging and Biodistribution of Gold Nanoparticle-Loaded Macrophages for Targeted Drug Delivery. Electronics, 2020, 9(7), 1105. doi: 10.3390/electronics9071105
  152. Camardo, A.; Carney, S.; Ramamurthi, A. Assessing the targeting and fate of cathepsin k antibody-modified nanoparticles in a rat abdominal aortic aneurysm model. Acta Biomaterialia, 2020, 112, 225–233. doi: 10.1016/j.actbio.2020.05.037
  153. Crawford, B.; Wang, H.-N.; Strobbia, P.; Zentella, R.; Pei, Z.-M.; Sun, T.-P.; Vo-Dinh, T. Plasmonic Nanobiosensing: from in situ plant monitoring to cancer diagnostics at the point of care. Journal of Physics: Photonics, 2020, 2(3), 034012. doi: 10.1088/2515-7647/ab9714
  154. Kim, D.; Singh, N.; Waldemer-Streyer, R.J.; Yoon, M.-S.; Chen, J. Muscle-derived TRAIL negatively regulates myogenic differentiation. Experimental Cell Research, 2020, 394(1), 112165. doi: 10.1016/j.yexcr.2020.112165
  155. Tolentino, M.Q.; Hartmann, A.K.; Loe, D.T.; Rouge, J.L. Controlled release of small molecules and proteins from DNA-surfactant stabilized metal organic frameworks. Journal of Materials Chemistry B, 2020, 8(26), 5627–5635. doi: 10.1039/d0tb00767f
  156. Cao, C.; Chen, F.; Garvey, C.J.; Stenzel, M.H. Drug-directed morphology changes in polymerization induced self-assembly (PISA) influences the biological behavior of nanoparticles. ACS Applied Materials & Interfaces, 2020, 12(27), 30221–30233. doi: 10.1021/acsami.0c09054
  157. Srinageshwar, B.; Florendo, M.; Clark, B.; Johnson, K.; Munro, N.; Peruzzaro, S.; Antcliff, A.; Andrews, M.; Figacz, A.; Swanson, D.; Dunbar, G.L.; Sharma, A.; Rossignol, J. A Mixed-Surface Polyamidoamine Dendrimer for In Vitro and In Vivo Delivery of Large Plasmids. Pharmaceutics, 2020, 12(7), 619. doi: 10.3390/pharmaceutics12070619
  158. Feng, C.; Ouyang, J.; Tang, Z.; Kong, N.; Liu, Y.; Fu, L.; Ji, X.; Xie, T.; Farokhzad, O.C.; Tao, W. Germanene-Based Theranostic Materials for Surgical Adjuvant Treatment: Inhibiting Tumor Recurrence and Wound Infection. Matter, 2020, 3(1), 127–144. doi: 10.1016/j.matt.2020.04.022
  159. Seo, J.-H.; Lee, S.Y.; Hwang, C.; Yang, M.; Lee, J.; Lee, S.-H.; Cho, H.-J. Multi-layered cellulose nanocrystal system for CD44 receptor-positive tumor-targeted anticancer drug delivery. International Journal of Biological Macromolecules, 2020, 162, 798–809. doi: 10.1016/j.ijbiomac.2020.06.193
  160. Hahn, F.; Niesar, A.; Wangen, C.; Wild, M.; Grau, B.; Herrmann, L.; Capci, A.; Adrait, A.; Couté, Y.; Tsogoeva, S.B.; Marschall, M. Target verification of artesunate-related antiviral drugs: assessing the role of mitochondrial and regulatory proteins by click chemistry and fluorescence labeling. Antiviral Research, 2020, 180, 104861. doi: 10.1016/j.antiviral.2020.104861
  161. Aronsson, C.; Jury, M.; Naeimipour, S.; Rasti Boroojeni, F.; Christoffersson, J.; Lifwergren, P.; Mandenius, C.-F.; Selegård, R.; Aili, D. Dynamic peptide-folding mediated biofunctionalization and modulation of hydrogels for 4D bioprinting. Biofabrication, 2020, 12(3), 035031. doi: 10.1088/1758-5090/ab9490
  162. Kleinpenning, F.; Steigenberger, B.; Wu, W.; Heck, A.J.R. Fishing for newly synthesized proteins with phosphonate-handles. Nature Communications, 2020, 11, 3244. doi: 10.1038/s41467-020-17010-0
  163. Luo, K.; Guo, W.; Yu, Y.; Xu, S.; Zhou, M.; Xiang, K.; Niu, K.; Zhu, X.; Zhu, G.; An, Z.; Yu, Q.; Gan, Z. Reduction-sensitive platinum (IV)-prodrug nano-sensitizer with an ultra-high drug loading for efficient chemo-radiotherapy of Pt-resistant cervical cancer in vivo. Journal of Controlled Release, 2020, 326, 25–37. doi: 10.1016/j.jconrel.2020.06.005
  164. Novoselova, M.V.; Abakumova, T.O.; Khlebtsov, B.N.; Zatsepin, T.S.; Lazareva, E.N.; Tuchin, V.V.; Zharov, V.P.; Gorin, D.A.; Galanzha, E.I. Optical clearing for photoacoustic lympho- and angiography beyond conventional depth limit in vivo. Photoacoustics, 2020, 20, 100186. doi: 10.1016/j.pacs.2020.100186
  165. Pink, M.; Verma, N.; Schmitz-Spanke, S. Benchmark dose analyses of toxic endpoints in lung cells provide sensitivity and toxicity ranking across metal oxide nanoparticles and give insights into the mode of action. Toxicology Letters, 2020, 331, 218–226. doi: 10.1016/j.toxlet.2020.06.012
  166. Sokolova, V.; Nzou, G.; van der Meer, S.B.; Ruks, T.; Heggen, M.; Loza, K.; Hagemann, N.; Murke, F.; Giebel, B.; Hermann, D.M.; Atala, A.J.; Epple, M. Ultrasmall gold nanoparticles (2 nm) can penetrate and enter cell nuclei in an in vitro 3D brain spheroid model. Acta Biomaterialia, 2020, 111, 349–362. doi: 10.1016/j.actbio.2020.04.023
  167. Nemec, A.A.; Tomko, R.J. A suite of PCR-based peptide tagging plasmids to permit epitope-targeted enzymatic functionalization of yeast proteins. Yeast, 2020, 37(5–6), 327–335. doi: 10.1002/yea.3471
  168. Xu, J.; Guo, J.; Golob-Schwarzl, N.; Haybaeck, J.; Qiu, X.; Hildebrandt, N. Single-measurement multiplexed quantification of microRNAs from human tissue using catalytic hairpin assembly and Förster resonance energy transfer. ACS Sensors, 2020, 5(6), 1768–1776. doi: 10.1021/acssensors.0c00432
  169. He, Y.; Ren, E.; Lu, Z.; Chen, H.; Qin, Z.; Wang, J.; He, M.; Liu, G.; Zheng, L.; Zhao, J. Rational engineering of ferritin Nanocages for targeted therapy of osteoarthritis. Nanomedicine, 2020, 28, in press. doi: 10.1016/j.nano.2020.102210
  170. Rojas-Sánchez, L.; Loza, K.; Epple, M. Synthesis and intracellular tracing surface-functionalized calcium phosphate nanoparticles by super-resolution microscopy (STORM). Materialia, 2020, 12, 100773. doi: 10.1016/j.mtla.2020.100773
  171. Phung, C.D.; Le, T.G.; Nguyen, V.H.; Vu, T.T.; Nguyen, H.Q.; Kim, J.O.; Yong, C.S.; Nguyen, C.N. PEGylated-Paclitaxel and Dihydroartemisinin Nanoparticles for Simultaneously Delivering Paclitaxel and Dihydroartemisinin to Colorectal Cancer. Pharmaceutical Research, 2020, 37, 129. doi: 10.1007/s11095-020-02819-7
  172. Bai, M.; Cao, X.; Huang, W.; Chen, F.; Zhao, Y.; Xue, J.; Li, Y.; Cheng, Y.; Zhang, L.; Zhao, Y. Visualizing Newly Synthesized RNA by Bioorthogonal Labeling-primed DNA Amplification. Analytical Chemistry, 2020, 92(12), 8444–8449. doi: 10.1021/acs.analchem.0c01161
  173. Safari, H.; Kelley, W.J.; Saito, E.; Kaczorowski, N.; Carethers, L.; Shea, L.D.; Eniola-Adefeso, O. Neutrophils preferentially phagocytose elongated particles {\textendash} An opportunity for selective targeting in acute inflammatory diseases. Science Advances, 2020, 6(24), eaba1474. doi: 10.1126/sciadv.aba1474
  174. Priwitaningrum, D.L.; Jentsch, J.; Bansal, R.; Rahimian, S.; Storm, G.; Hennink, W.E.; Prakash, J. Apoptosis-inducing Peptide Loaded in PLGA Nanoparticles Induces Anti-tumor Effects in vivo. International Journal of Pharmaceutics, 2020, 585, 119535. doi: 10.1016/j.ijpharm.2020.119535
  175. Emaus, M.N.; Anderson, J.L. Allelic discrimination between circulating tumor DNA fragments enabled by a multiplex-qPCR assay containing DNA-enriched magnetic ionic liquids. Analytica Chimica Acta, 2020, 1124, 184–193. doi: 10.1016/j.aca.2020.04.078
  176. Arraf, A.A.; Yelin, R.; Reshef, I.; Jadon, J.; Abboud, M.; Zaher, M.; Schneider, J.; Vladimirov, F.K.; Schultheiss, T.M. Hedgehog Signaling Regulates Epithelial Morphogenesis to Position the Ventral Embryonic Midline. Developmental Cell, 2020, 53(5), 589–602.e6. doi: 10.1016/j.devcel.2020.04.016
  177. Vora, P.; Venugopal, C.; Salim, S.K.; Tatari, N.; Bakhshinyan, D.; Singh, M.; Seyfrid, M.; Upreti, D.; Rentas, S.; Wong, N.; Williams, R.; Qazi, M.A.; Chokshi, C.; Ding, A.; Subapanditha, M.; Savage, N.; Mahendram, S.; Ford, E.; Adile, A.A.; McKenna, D.; McFarlane, N.; Huynh, V.; Wylie, R.G.; Pan, J.; Bramson, J.; Hope, K.; Moffat, J.; Singh, S. The Rational Development of CD133-Targeting Immunotherapies for Glioblastoma. Cell Stem Cell, 2020, 26(6), 832–844.e6. doi: 10.1016/j.stem.2020.04.008
  178. Bhattacharya, D.S.; Svechkarev, D.A.; Bapat, A.; Patil, P.; Hollingsworth, M.A.; Mohs, A.M. Sulfation modulates the targeting properties of hyaluronic acid to P-selectin and CD44. ACS Biomaterials Science & Engineering, 2020, 6(6), 3585–3598. doi: 10.1021/acsbiomaterials.0c00115
  179. Ridolfo, R.; Arends, J.J.; van Hest, J.C.M.; Williams, D.S. Worm-like nanovector with enhanced drug loading using blends of biodegradable block copolymers. Biomacromolecules, 2020, 21(6), 2199–2207. doi: 10.1021/acs.biomac.0c00169
  180. Zhao, Y.; Fletcher, N.L.; Gemmell, A.; Houston, Z.H.; Howard, C.B.; Blakey, I.; Liu, T.; Thurecht, K.J. Investigation of the Therapeutic Potential of a Synergistic Delivery System through Dual Controlled Release of Camptothecin–Doxorubicin. Advanced Therapeutics, 2020, 3(6), 1900202. doi: 10.1002/adtp.201900202
  181. Mayorova, O.A.; Sindeeva, O.A.; Lomova, M.V.; Gusliakov, O.I.; Tarakanchikova, Y.V.; Tyutyaev, E.V.; Pinyaev, S.I.; Kulikov, O.A.; German, S.V.; Pyataev, N.A.; Gorin, D.A.; Sukhorukov, G.B. Endovascular addressing improves the effectiveness of magnetic targeting of drug carrier. Comparison with the conventional administration method. Nanomedicine, 2020, 28, 102184. doi: 10.1016/j.nano.2020.102184
  182. Palumbo, C.M.; Gutierrez-Bujari, J.M.; O'Geen, H.; Segal, D.J.; Beal, P. Versatile 3' Functionalization of CRISPR Single Guide RNA. ChemBioChem, 2020, 21(11), 1633–1640. doi: 10.1002/cbic.201900736
  183. Hellyer, S.D.; Aggarwal, S.; Chen, A.N.; Leach, K.; Lapinsky, D.J.; Gregory, K.J. Development of Clickable Photoaffinity Ligands for Metabotropic Glutamate Receptor 2 Based on Two Positive Allosteric Modulator Chemotypes. ACS Chemical Neuroscience, 2020, 11(11), 1597–1609. doi: 10.1021/acschemneuro.0c00009
  184. Moutsiopoulou, A.; Broyles, D.; Joda, H.; Dikici, E.; Kaur, A.; Kaifer, A.E.; Daunert, S.; Deo, S.K. Bioluminescent Protein-Inhibitor Pair in the Design of a Molecular Aptamer Beacon Biosensing System. Analytical Chemistry, 2020, 92(11), 7393–7398. doi: 10.1021/acs.analchem.0c00518
  185. Shunatova, N.; Borisenko, I. Proliferating activity in a bryozoan lophophore. PeerJ, 2020, 8, e9179. doi: 10.7717/peerj.9179
  186. Alfaifi, A.A.; Heyder, R.S.; Bielski, E.R.; Almuqbil, R.M.; Kavdia, M.; Gerk, P.M.; da Rocha, S.R.P. Megalin-targeting liposomes for placental drug delivery. Journal of Controlled Release, 2020, 324, 366–378. doi: 10.1016/j.jconrel.2020.05.033
  187. Möltgen, S.; Piumatti, E.; Massafra, G.M.; Metzger, S.; Jaehde, U.; Kalayda, G.V. Cisplatin Protein Binding Partners and Their Relevance for Platinum Drug Sensitivity. Cells, 2020, 9, 1322. doi: 10.3390/cells9061322
  188. Gonzales, J.; Pirovano, G.; Chow, C.Y.; de Souza Franca, P.D.; Carter, L.M.; Klint, J.K.; Guru, N.; Lewis, J.S.; King, G.F.; Reiner, T. Fluorescence labeling of a Nav1.7-targeted peptide for near-infrared nerve visualization. EJNMMI Research, 2020, 10, 49. doi: 10.1186/s13550-020-00630-4
  189. Matoori, S.; Mooney, D.J. Near-Infrared Fluorescence Hydrogen Peroxide Assay for Versatile Metabolite Biosensing in Whole Blood. Small, 2020, 16(20), 2000369. doi: 10.1002/smll.202000369
  190. Wang, C.; Fernández de Ávila, B.E.; Mundaca-Uribe, R.; Lopez-Ramirez, M.A.; Ramírez-Herrera, D.E.; Shukla, S.; Steinmetz, N.F.; Wang, J. Active Delivery of VLPs Promotes Anti-Tumor Activity in a Mouse Ovarian Tumor Model. Small, 2020, 16(20), e1907150. doi: 10.1002/smll.201907150
  191. Levada, K.; Pshenichnikov, S.; Omelyanchik, A.; Rodionova, V.; Nikitin, A.; Savchenko, A.; Schetinin, I.; Zhukov, D.; Abakumov, M.; Majouga, A.; Lunova, M.; Jirsa, M.; Smolková, B.; Uzhytchak, M.; Dejneka, A.; Lunov, O. Progressive lysosomal membrane permeabilization induced by iron oxide nanoparticles drives hepatic cell autophagy and apoptosis. Nano Convergence, 2020, 7, 17. doi: 10.1186/s40580-020-00228-5
  192. Sheshachala, S.; Grösche, M.; Scherr, T.; Hu, Y.; Sun, P.; Bartschat, A.; Mikut, R; Niemeyer, C.M. Segregation of dispersed silica nanoparticles in microfluidic water in oil droplets: A kinetic study. ChemPhysChem, 2020, 21(10), 1070–1078. doi: 10.1002/cphc.201901151
  193. Reed, S.A.; Brzovic, D.A.; Takasaki, S.S.; Boyko, K.V.; Antos, J.M. Efficient Sortase-Mediated Ligation Using a Common C-Terminal Fusion Tag. Bioconjugate Chemistry, 2020, 31(5), 1463–1473. doi: 10.1021/acs.bioconjchem.0c00156
  194. Deng, L.; Huang, X.; Ren, J. In Situ Study of the Drug-target Protein Interaction in Single Living Cells by Combining Fluorescence Correlation Spectroscopy with Affinity Probes. Analytical Chemistry, 2020, 92(10), 7020–7027. doi: 10.1021/acs.analchem.0c00263
  195. Strobbia, P.; Odion, R.A.; Maiwald, M.; Sumpf, B.; Vo-Dinh, T. Direct SERDS sensing of molecular biomarkers in plants under field conditions. Analytical and Bioanalytical Chemistry, 2020, 412(14), 3457–3466. doi: 10.1007/s00216-020-02544-5
  196. Wang, J.; Li, Y.; Li, L.; Yang, J.; Kopeček, J. Exploration and Evaluation of Therapeutic Efficacy of Drug-Free Macromolecular Therapeutics in Collagen-Induced Rheumatoid Arthritis Mouse Model. Macromolecular Bioscience, 2020, 20(5), e1900445. doi: 10.1002/mabi.201900445
  197. Xu, N.; Yang, Y.-F.; Chen, L.; Lin, J. A Ferritin–Albumin–Cu Nanoparticle that Efficaciously Delivers Copper(II) Ions to a Tumor and Improves the Therapeutic Efficacy of Disulfiram. ACS Omega, 2020, 5(18), 10415–10422. doi: 10.1021/acsomega.0c00293
  198. Wang, S.P.; Cao, S.; Arhatte, M.; Li, D.; Shi, Y.; Kurz, S.; Hu, J.; Wang, L.; Shao, J.; Atzberger, A.; Wang, Z.; Wang, C.; Zang, W.; Fleming, I.; Wettschureck, N:, Honoré, E.; Offermanns, S. Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice. Nature Communications, 2020, 11, 2303. doi: 10.1038/s41467-020-16026-w
  199. Rodríguez-Hakim, M.; Anand, S.; Tajuelo, J.; Yao, Z.; Kannan, A.; Fuller, G.G. Asphaltene-induced spontaneous emulsification: Effects of interfacial co-adsorption and viscoelasticity. Journal of Rheology, 2020, 64(4), 799–816. doi: 10.1122/1.5145307
  200. Korzhikov-Vlakh, V.; Katernuk, I.; Pilipenko, I.; Lavrentieva, A.; Guryanov, I.; Sharoyko, V.; Manshina, A.A.; Tennikova, T.B. Photosensitive Poly-L-lysine/Heparin Interpolyelectrolyte Complexes for Delivery of Genetic Drugs. Polymers, 2020, 12(5), 1077. doi: 10.3390/polym12051077
  201. Radman, S.; Raić, S.; Bućan, I.; Pribisalić, A.; Dunatov, J.; Mudnić, I.; Boban, M.; Pellay, F.X.; Kolčić, I.; Polašek, O. Searching for carbonylome biomarkers of aging – development and validation of the proteomic method for quantification of carbonylated protein in human plasma. Croatian Medical Journal, 2020, 61(2), 119–125. doi: 10.3325/cmj.2020.61.119
  202. Monteiro, P.F.; Gulfam, M.; Monteiro, C.J.; Travanut, A.; Abelha, T.F.; Pearce, A.K.; Jerôme, C.; Grabowska, A.M.; Clarke, P.A.; Collins, H.M.; Heery, D.M.; Gershkovich, P.; Alexander, C. Synthesis of micellar-like terpolymer nanoparticles with reductively-cleavable cross-links and evaluation of efficacy in 2D and 3D models of triple negative breast cancer. Journal of Controlled Release, 2020, 323, 549–564. doi: 10.1016/j.jconrel.2020.04.049
  203. Sabeti Azad, M.; Okuda, M.; Cyrenne, M.; Bourge, M.; Heck, M.-P.; Yoshizawa, S.; Fourmy, D. Fluorescent Aminoglycoside Antibiotics and Methods for Accurately Monitoring Uptake by Bacteria. ACS Infectious Diseases, 2020, 6(5), 1008–1017. doi: 10.1021/acsinfecdis.9b00421
  204. Alberg, I.; Kramer, S.; Schinnerer, M.; Hu, Q.; Seidl, C.; Leps, C.; Drude, N.; Möckel, D.; Rijcken, C.; Lammers, T.; Diken, M.; Maskos, M.; Morsbach, S.; Landfester, K.; Tenzer, S.; Barz, M.; Zentel, R. Polymeric Nanoparticles with Neglectable Protein Corona. Small, 2020, 16(18), 1907574. doi: 10.1002/smll.201907574
  205. Syga, L.; De Vries, R.H.; van Oosterhout, H.; Bartelds, R.; Boersma, A.J.; Roelfes, G.; Poolman, B. A trifunctional linker for palmitoylation and peptide and protein localization in biological membranes. ChemBioChem, 2020, 21(9), 1320–1328. doi: 10.1002/cbic.201900655
  206. Ko, Y.J.; Lee, J.W.; Kim, H.; Cho, E.; Yang, Y.; Kim, I.-S.; Kim, S.H.; Kwon, I.C. Versatile activatable vSIRPα-probe for cancer-targeted imaging and macrophage-mediated phagocytosis of cancer cells. Journal of Controlled Release, 2020, 323, 376–386. doi: 10.1016/j.jconrel.2020.04.037
  207. Leonard, D.; Huang, W.; Izadmehr, S.; O'Connor, C.M.; Wiredja, D.D.; Wang, Z.; Zaware, N.; Chen, Y.; Schlatzer, D.M.; Kiselar, J.; Vasireddi, N.; Schüchner, S.; Perl, A.L.; Galsky, M.D.; Xu, W.; Brautigan, D.L.; Ogris, E.; Taylor, D.J.; Narla, G. Selective PP2A Enhancement through Biased Heterotrimer Stabilization. Cell, 2020, 181(3), 688–701.e16. doi: 10.1016/j.cell.2020.03.038
  208. Chen, Y.; Shen, W.; Tang, C.; Huang, J.; Fan, C.; Yin, Z.; Hu, Y.; Chen, W.; Ouyang, H.; Zhou, Y.; Mao, Z.; Chen, X. Targeted pathological collagen delivery of sustained-release rapamycin to prevent heterotopic ossification. Science Advances, 2020, 6(18), eaay9526. doi: 10.1126/sciadv.aay9526
  209. von Döhren, J.; Kuhl, S. A simple method for long-term vital-staining of ciliated epidermal cells in aquatic larvae. Journal of Biological Methods, 2020, 7(2), e132. doi: 10.14440/jbm.2020.320
  210. Bao, X.; Qian, K.; Yao, P. Oral delivery of exenatide-loaded hybrid zein nanoparticles for stable blood glucose control and β-cell repair of type 2 diabetes mice. Journal of Nanobiotechnology, 2020, 18, 67. doi: 10.1186/s12951-020-00619-0
  211. Cioloboc, D.; Kurtz, D.M. Targeted cancer cell delivery of arsenate as a reductively activated prodrug. Journal of Biological Inorganic Chemistry, 2020, 25(3), 441–449. doi: 10.1007/s00775-020-01774-3
  212. Cutie, S.; Payumo, A.Y.; Lunn, D.; Huang, G.N. In vitro and in vivo roles of glucocorticoid and vitamin D receptors in the control of neonatal cardiomyocyte proliferative potential. Journal of Molecular and Cellular Cardiology, 2020, 142, 126–134. doi: 10.1016/j.yjmcc.2020.04.013
  213. Zaytsev, S.M.; Svenskaya, Y.I.; Lengert, E.V.; Terentyuk, G.S.; Bashkatov, A.N.; Tuchin, V.V.; Genina, E.A. Optimized skin optical clearing for Optical Coherence Tomography monitoring of encapsulated drug delivery through the hair follicles. Journal of Biophotonics, 2020, 13(4), e201960020. doi: 10.1002/jbio.201960020
  214. Yoshikawa, T.; Quoc Phan, K.; Tagawa, H.; Sasaki, K.; Feng, H.; Kishimura, A.; Mori, T.; Katayama, Y. Modification of nitric oxide donors onto a monoclonal antibody boosts accumulation in solid tumors. International Journal of Pharmaceutics, 2020, 583, 119352. doi: 10.1016/j.ijpharm.2020.119352
  215. Fodor-Kardos, A.; Kiss, Á.F.; Monostory, K.; Feczkó, T. Sustained in vitro interferon-beta release and in vivo toxicity of PLGA and PEG-PLGA nanoparticles. RSC Advances, 2020, 10(27), 15893–15900. doi: 10.1039/c9ra09928j
  216. Chen, Q.; Gao, M.; Li, Z.; Xiao, Y.; Bai, X.; Boakye-Yiadom, K.O.; Xu, X.; Zhang, X.-Q. Biodegradable nanoparticles decorated with different carbohydrates for efficient macrophage-targeted gene therapy. Journal of Controlled Release, 2020, 323, 179–190. doi: 10.1016/j.jconrel.2020.03.044
  217. Walker, J.A.T.; Wang, X.; Peter, K.; Kempe, K.; Corrie, S.R. Dynamic solid-state ultrasound contrast agent for monitoring pH fluctuations in vivo. ACS Sensors, 2020, 5(4), 1190–1197. doi: 10.1021/acssensors.0c00245
  218. Ren, J.; Yin, X.; Chen, Y.; Chen, Y.; Su, H.; Wang, K.; Zhang, L.; Zhu, J.; Zhang, C. Alginate hydrogel-coated syringe needles for rapid haemostasis of vessel and viscera puncture. Biomaterials, 2020, 249, 120019. doi: 10.1016/j.biomaterials.2020.120019
  219. Guo, H.; Song, S.; Dai, T.; Sun, K.; Zhou, G.; Li, M.; Mann, S.; Dou, H. Near-Infrared Fluorescent and Magnetic Resonance Dual-Imaging Coacervate Nanoprobes for Trypsin Mapping and Targeted Payload Delivery of Malignant Tumors. ACS Applied Materials & Interfaces, 2020, 12(15), 17302–17313. doi: 10.1021/acsami.0c03433
  220. Schwegmann, K.; Hohn, M.; Hermann, S.; Schäfers, M.; Riemann, B.; Haufe, G.; Wagner, S.; Breyholz, H.-J. Optimizing the biodistribution of radiofluorinated barbiturate tracers for MMP imaging by introduction of fluorescent dyes as pharmacokinetic modulators. Bioconjugate Chemistry, 2020, 31(4), 1117–1132. doi: 10.1021/acs.bioconjchem.9b00817
  221. Ryu, J.S.; Im, S.H.; Kang, Y.K.; Kim, Y.S.; Chung, H.J. Ultra-fast and universal detection of Gram-negative bacteria in complex samples based on colistin derivatives. Biomaterials Science, 2020, 8(8), 2111–2119. doi: 10.1039/c9bm01926j
  222. Mindubaev, A.Z.; Kuznetsova, S.V.; Evtyugin, V.G.; Daminova, A.G.; Grigoryeva, T.V.; Romanova, Y.D.; Romanova, V.A.; Babaev, V.M.; Buzyurova, D.N.; Babynin, E.V.; Badeeva, E.K.; Minzanova, S.T.; Mironova, L.G. Effect of White Phosphorus on the Survival, Cellular Morphology, and Proteome of Aspergillus niger. Applied Biochemistry and Microbiology, 2020, 56(2), 194–201. doi: 10.1134/S0003683820020118
  223. Liu, Y.; Fens, M.H.A.M.; Lou, B.; van Kronenburg, N.C.H.; Maas-Bakker, R.F.M.; Kok, R.J.; Oliveira, S.; Hennink, W.E.; van Nostrum, C.F. π-π-Stacked Poly(ε-caprolactone)-b-poly(ethylene glycol) Micelles Loaded with a Photosensitizer for Photodynamic Therapy. Pharmaceutics, 2020, 12(4), 338. doi: 10.3390/pharmaceutics12040338
  224. Jiang, S.; Mottola, M.; Han, S.; Thiramanas, R.; Graf, R.; Lieberwirth, I.; Mailänder, V.; Crespy, D.; Landfester, K. Versatile Preparation of Silica Nanocapsules for Biomedical Applications. Particle & Particle Systems Characterization, 2020, 37(4), 1900484. doi: 10.1002/ppsc.201900484
  225. Taipaleenmäki, E.; Christensen, G.; Brodszkij, E.; Mouritzen, S.A.; Gal, N.; Madsen, S.; Hedemann, M.S.; Knudsen, T.A.; Jensen, H.M.; Christiansen, S.L.; Sparsø, F.V.; Städler, B. Mucopenetrating polymer - Lipid hybrid nanovesicles as subunits in alginate beads as an oral formulation. Journal of Controlled Release, 2020, 322, 470–485. doi: 10.1016/j.jconrel.2020.03.047
  226. Qiu, J.; Li, X.; Steenkeste, K.; Barroca-Aubry, N.; Aymes-Chodur, C.; Roger, P.; Casas-Solvas, J.M.; Vargas-Berenguel, A.; Rihouey, C.; Picton, L.; Gref, R. Self-assembled multifunctional core-shell highly porous metal-organic framework nanoparticles. International Journal of Pharmaceutics, 2020, 581, 119281. doi: 10.1016/j.ijpharm.2020.119281
  227. Terekhov, S.S.; Nazarov, A.S.; Mokrushina, Y.A.; Baranova, M.N.; Potapova, N.A.; Malakhova, M.V.; Ilina, E.N.; Smirnov, I.V.; Gabibov, A.G. Deep Functional Profiling Facilitates the Evaluation of the Antibacterial Potential of the Antibiotic Amicoumacin. Antibiotics, 2020, 9(4), 157. doi: 10.3390/antibiotics9040157
  228. Sagert, L.; Hennig, F.; Thomas, C.; Tampé, R. A loop structure allows TAPBPR to exert its dual function as MHC I chaperone and peptide editor. eLife, 2020, 9, e55326. doi: 10.7554/eLife.55326
  229. Liu, Y.; Scrivano, L.; Peterson, J.D.; Fens, M.H.A.M.; Beltrán Hernández, I.; Mesquita, B.; Sastre Torano, J.; Hennink, W.E.; van Nostrum, C.F.; Oliveira, S. EGFR targeted nanobody functionalized polymeric micelles loaded with mTHPC for selective photodynamic therapy. Molecular Pharmaceutics, 2020, 17(4), 1276–1292. doi: 10.1021/acs.molpharmaceut.9b01280
  230. Al-Lawati, H.; Vakili, M.R.; Lavasanifar, A.; Ahmed, S.; Jamali, F. Reduced heart exposure of diclofenac by its polymeric micellar formulation, normalizes CYP- mediated metabolism of arachidonic acid imbalance in adjuvant arthritis rat model: Implications in reduced cardiovascular side effects of diclofenac by ... Molecular Pharmaceutics, 2020, 17(4), 1377–1386. doi: 10.1021/acs.molpharmaceut.0c00069
  231. Li, Q.; Wang, F.; Yang, J.; Liu, D. Direct cytoplasm delivery of gold nanoparticles for real-time apoptosis detection. Nano Research, 2020, 13(3), 853–860. doi: 10.1007/s12274-020-2707-y
  232. Shukla, S.; Wang, C.; Beiss, V.; Steinmetz, N.F. Antibody Response against Cowpea Mosaic Viral Nanoparticles Improves In Situ Vaccine Efficacy in Ovarian Cancer. ACS Nano, 2020, 14(3), 2994–3003. doi: 10.1021/acsnano.9b07865
  233. Jordan, T.; O’Brien, M.A.; Spatarelu, C.-P.; Luke, G.P. Antibody-Conjugated Barium Titanate Nanoparticles for Cell-Specific Targeting. ACS Applied Nano Materials, 2020, 3(3), 2636–2646. doi: 10.1021/acsanm.0c00019
  234. Kołt, S.; Janiszewski, T.; Kaiserman, D.; Modrzycka, S.; Snipas, S.J.; Salvesen, G.; Dra G, M.; Bird, P.I.; Kasperkiewicz, P. Detection of Active Granzyme A in NK92 Cells with Fluorescent Activity-Based Probe. Journal of Medicinal Chemistry, 2020, 63(6), 3359–3369. doi: 10.1021/acs.jmedchem.9b02042
  235. Peeler, D.J.; Luera, N.; Horner, P.J.; Pun, S.H.; Sellers, D.L. Polyplex transfection from intracerebroventricular delivery is not significantly affected by traumatic brain injury. Journal of Controlled Release, 2020, 322, 149–156. doi: 10.1016/j.jconrel.2020.03.025
  236. Zhang, E.; Zhukova, V.; Semyonkin, A.; Osipova, N.; Malinovskaya, Y.; Maksimenko, O.; Chernikov, V.; Sokolov, M.; Grigartzik, L.; Sabel, B.A.; Gelperina, S.; Henrich-Noack, P. Release kinetics of fluorescent dyes from PLGA nanoparticles in retinal blood vessels: in vivo monitoring and ex vivo localization. European Journal of Pharmaceutics and Biopharmaceutics, 2020, 150, 131–142. doi: 10.1016/j.ejpb.2020.03.006
  237. Yu, Y.; Guo, Y.; Tian, Q.; Lan, Y.; Yeh, H.; Zhang, M.; Tasan, I.; Jain, S.; Zhao, H. An efficient gene knock-in strategy using 5'-modified double-stranded DNA donors with short homology arms. Nature Chemical Biology, 2020, 16(4), 387–390. doi: 10.1038/s41589-019-0432-1
  238. Qi, B.; Crawford, A.J.; Wojtynek, N.E.; Talmon, G.A.; Hollingsworth, M.A.; Ly, Q.P.; Mohs, A.M. Tuned near infrared fluorescent hyaluronic acid conjugates for delivery to pancreatic cancer for intraoperative imaging. Theranostics, 2020, 10(8), 3413–3429. doi: 10.7150/thno.40688
  239. Pfister, J.; Summer, D.; Petrik, M.; Khoylou, M.; Lichius, A.; Kaeopookum, P.; Kochinke, L.; Orasch, T.; Haas, H.; Decristoforo, C. Hybrid Imaging of Aspergillus fumigatus Pulmonary Infection with Fluorescent, 68Ga-Labelled Siderophores. Biomolecules, 2020, 10, 168. doi: 10.3390/biom10020168
  240. Tan, M.S.Y.; Davison, D.; Sanchez, M.I.; Anderson, B.M.; Howell, S.; Snijders, A.; Edgington-Mitchell, L.E.; Deu, E. Novel broad-spectrum activity-based probes to profile malarial cysteine proteases. PLoS One, 2020, 15(1), e0227341. doi: 10.1371/journal.pone.0227341
  241. Zhong, Y.; Sun, R.; Geng, Y.; Zhou, Q.; Piao, Y.; Xie, T.; Zhou, R.; Shen, Y. N-Oxide polymer-cupric ion nanogels potentiate disulfiram for cancer therapy. Biomaterials Science, 2020, 8(6), 1726–1733. doi: 10.1039/c9bm01841g
  242. Zhang, Y.; García-Gabilondo, M.; Grayston, A.; Feiner, I.V.J.; Anton-Sales, I.; Loiola, R.A.; Llop, J.; Ramos-Cabrer, P.; Barba, I:; Garcia-Dorado, D.; Gosselet, F.; Rosell, A.; Roig, A. PLGA protein nanocarriers with tailor-made fluorescence/MRI/PET imaging modalities. Nanoscale, 2020, 12(8), 4988–5002. doi: 10.1039/c9nr10620k
  243. Beri, D.; Jakoby, M.; Howard, I.A.; Busko, D.; Richards, B.S.; Turshatov, A. Improved photon absorption in dye-functionalized silicon nanocrystals synthesized via microwave-assisted hydrosilylation. Dalton Transactions, 2020, 49(7), 2290–2299. doi: 10.1039/c9dt04497c
  244. Jiang, S.; Prozeller, D.; Pereira, J.; Simon, J.; Han, S.; Wirsching, S.; Fichter, M.; Mottola, M.; Lieberwirth, I.; Morsbach, S.; Mailänder, V.; Gehring, S.; Crespy, D.; Landfester, K. Controlling protein interactions in blood for effective liver immunosuppressive therapy by silica nanocapsules. Nanoscale, 2020, 12(4), 2626–2637. doi: 10.1039/c9nr09879h
  245. Maklakova, S.Y.; Naumenko, V.A.; Chuprov, A.D.; Mazhuga, M.P.; Zyk, N.V.; Beloglazkina, E.K.; Majouga, A.G. Cellular uptake of N-acetyl-d-galactosamine-, N-acetyl-d-glucosamine- and d-mannose-containing fluorescent glycoconjugates investigated by liver intravital microscopy. Carbohydrate Research, 2020, 489, 107928. doi: 10.1016/j.carres.2020.107928
  246. Kwon, S.-H.; Wi, T.; Park, Y.I.; Kim, M.W.; Lee, G.; Higaki, T.; Choi, J.H.; Lee, R. Non-invasive early detection of calpain 2-enriched non-small cell lung cancer using a human serum albumin-bounded calpain 2 nanosensor. Bioconjugate Chemistry, 2020, 31(3), 803–812. doi: 10.1021/acs.bioconjchem.9b00870
  247. Wouters, S.; Vugs, W.; Arts, R.; de Leeuw, N.; Teeuwen, R.; Merkx, M. Bioluminescent antibodies through photoconjugation of protein-G-luciferase fusion proteins. Bioconjugate Chemistry, 2020, 31(3), 656–662. doi: 10.1021/acs.bioconjchem.9b00804
  248. Yamada, K.J.; Heim, C.E.; Xi, X.; Attri, K.S.; Wang, D.; Zhang, W.; Singh, P.K.; Bronich, T.K.; Kielian, T. Monocyte metabolic reprogramming promotes pro-inflammatory activity and Staphylococcus aureus biofilm clearance. PLoS Pathogens, 2020, 16(3), e1008354. doi: 10.1371/journal.ppat.1008354
  249. Xu, Y.; Deng, Z.; Shi, Y.; Chen, X.; Xu, J.; Zhong, S.; Xiao, Y.; Wong, N.-K.; Zhou, Y. Molecular Imaging and In Situ Quantitative Profiling of Fatty Acid Synthase with a Chemical Probe. Analytical Chemistry, 2020, 92(6), 4419–4426. doi: 10.1021/acs.analchem.9b05327
  250. He, X.; Yuan, Z.; Kao, W.; Miller, D.; Li, S.K.; Park, Y.C. Size-Exclusive Nanoporous Biodegradable PLGA Capsules for Drug Delivery Implants and In Vivo Stability in the Posterior Segment. ACS Applied Bio Materials, 2020, 3(3), 1722–1729. doi: 10.1021/acsabm.0c00027
  251. Zahn, T.; Akhras, S.; Spengler, C.; Murra, R.O.; Holzhauser, T.; Hildt, E. A new approach for therapeutic vaccination against chronic HBV infections. Vaccine, 2020, 38(15), 3105–3120. doi: 10.1016/j.vaccine.2020.02.063
  252. Stein, L.M.; Lhamo, R.; Cao, A.; Workinger, J.; Tinsley, I.; Doyle, R.P.; Grill, H.J.; Hermann, G.E.; Rogers, R.C.; Hayes, M.R. Dorsal vagal complex and hypothalamic glia differentially respond to leptin and energy balance dysregulation. Translational Psychiatry, 2020, 10, 90. doi: 10.1038/s41398-020-0767-0
  253. Saez Talens, V.; Arias-Alpizar, G.; Makurat, D.M.M.; Davis, J.; Bussmann, J.; Kros, A.; Kieltyka, R.E. Stab2-Mediated Clearance of Supramolecular Polymer Nanoparticles in Zebrafish Embryos. Biomacromolecules, 2020, 21(3), 1060–1068. doi: 10.1021/acs.biomac.9b01318
  254. Shao, Z.; Flynn, R.A.; Crowe, J.L.; Zhu, Y.; Liang, J.; Jiang, W.; Aryan, F.; Aoude, P.; Bertozzi, C.R.; Estes, V.M.; Lee, B.J.; Bhagat, G.; Zha, S.; Calo, E. DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis. Nature, 2020, 579, 291–296. doi: 10.1038/s41586-020-2041-2
  255. Comeo, E.; Kindon, N.D.; Soave, M.; Stoddart, L.A.; Kilpatrick, L.; Scammells, P.J.; Hill, S.J.; and Kellam, B. Subtype-selective Fluorescent Ligands as Pharmacological Research Tools for the Human Adenosine A2A Receptor. Journal of Medicinal Chemistry, 2020, 63(5), 2656–2672. doi: 10.1021/acs.jmedchem.9b01856
  256. Stinson, B.M.; Moreno, A.T.; Walter, J.C.; Loparo, J.J. A Mechanism to Minimize Errors during Non-homologous End Joining. Molecular Cell, 2020, 77(5), 1080–1091.e8. doi: 10.1016/j.molcel.2019.11.018
  257. Yuan, X.; Liu, L.; Wang, W.; Gao, Y.-R.; Zhang, D.; Jia, T.-T.; Zeng, H.-R.; Pan, G.; Yuan, Y. Development of (G3-C12)-mediated camptothecin polymeric prodrug targeting to Galectin-3 receptor against androgen-independent prostate cancer. International Journal of Pharmaceutics, 2020, 580, 119123. doi: 10.1016/j.ijpharm.2020.119123
  258. Pereira de Sousa, I.; Gourmel, C.; Berkovska, O.; Burger, M.; Leroux, J.-C. A microparticulate based formulation to protect therapeutic enzymes from proteolytic digestion: phenylalanine ammonia lyase as case study. Scientific Reports, 2020, 10, 3651. doi: 10.1038/s41598-020-60463-y
  259. Braunová, A.; Chytil, P.; Laga, R.; Šírová, M.; Machová, D.; Parnica, J.; Janoušková, O.; Etrych, T. Polymer nanomedicines based on micelle-forming amphiphilic or water-soluble polymer-doxorubicin conjugates: Comparative study of in vitro and in vivo properties related to the polymer carrier structure, composition, and hydrodynamic properties. Journal of Controlled Release, 2020, 321, 718–733. doi: 10.1016/j.jconrel.2020.03.002
  260. Sodano, F.; Cavanagh, R.; Pearce, A.K.; Lazzarato, L.; Rolando, B.; Fraix, A.; Abelha, T.F.; Vasey, C.; Alexander, C.; Taresco, V.; Sortino, S. Enhancing Doxorubicin Anticancer Activity with a Novel Polymeric Platform Photoreleasing Nitric Oxide. Biomaterials Science, 2020, 8(5), 1329–1344. doi: 10.1039/c9bm01644a
  261. Viegas, A.; Dollinger, P.; Verma, N.; Kubiak, J.; Viennet, T.; Seidel, C.A.M.; Gohlke, H.; Etzkorn, M.; Kovacic, F.; Jaeger, K.-E. Structural and dynamic insights revealing how lipase binding domain MD1 of Pseudomonas aeruginosa foldase affects lipase activation. Scientific Reports, 2020, 10, 3578. doi: 10.1038/s41598-020-60093-4
  262. Basu, U.; Lee, S.-W.; Deshpande, A.; Shen, J.; Sohn, B.-K.; Cho, H.; Kim, H.; Patel, S.S. The C-terminal tail of the yeast mitochondrial transcription factor Mtf1 coordinates template strand alignment, DNA scrunching and timely transition into elongation. Nucleic Acids Research, 2020, 48(5), 2604–2620. doi: 10.1093/nar/gkaa040
  263. Kosciuk, T.; Price, I.R.; Zhang, X.; Zhu, C.; Johnson, K.N.; Zhang, S.; Halaby, S.L.; Komaniecki, G.P.; Yang, M.; DeHart, C.J.; Thomas, P.M.; Kelleher, N.L.; Fromme, J.C.; Lin, H. NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle. Nature Communications, 2020, 11, 1067. doi: 10.1038/s41467-020-14893-x
  264. Ecke, M.; Prassler, J.; Tanribil, P.; Müller-Taubenberger, A.; Körber, S.; Faix, J.; Gerisch, G. Formins specify membrane patterns generated by propagating actin waves. Molecular Biology of the Cell, 2020, 31(5), 373–385. doi: 10.1091/mbc.E19-08-0460
  265. Zhou, J.; Wang, W.; Zhang, J.; Du, Z.; Yang, H.; Zhang, G. Click chemistry-based imaging to study tissue distribution of curcumin-protein complex in mice. Food & Function, 2020, 11(2), 1684–1691. doi: 10.1039/c9fo02012h
  266. Landgraf, M.; Lahr, C.A.; Kaur, I.; Shafiee, A.; Sanchez-Herrero, A.; Janowicz, P.W.; Ravichandran, A.; Howard, C.B.; Cifuentes-Rius, A.; McGovern, J.A.; Voelcker, N.H.; Hutmacher, D.W. Targeted camptothecin delivery via silicon nanoparticles reduces breast cancer metastasis. Biomaterials, 2020, 240, 119791. doi: 10.1016/j.biomaterials.2020.119791
  267. Baranova, N.; Radler, P.; Hernández-Rocamora, V.M.; Alfonso, C.; López-Pelegrin, M.; Rivas, G.; Vollmer, W.; Loose, M. Diffusion and capture permits dynamic coupling between treadmilling FtsZ filaments and cell division proteins. Nature Microbiology, 2020, 5, 407–417. doi: 10.1038/s41564-019-0657-5
  268. Akhter, D.T.; Simpson, J.D.; Fletcher, N.L.; Houston, Z.H.; Fuchs, A.V.; Bell, C.A.; Thurecht, K.J. Oral Delivery of Multicompartment Nanomedicines for Colorectal Cancer Therapeutics: Combining Loco-Regional Delivery with Cell-Target Specificity. Advanced Therapeutics, 2020, 3(2), 1900171. doi: 10.1002/adtp.201900171
  269. Choi, J.; Marks, J.; Zhang, J.; Chen, D.-H.; Wang, J.; Vázquez-Laslop, N.; Mankin, A.S:; Puglisi, J.D. Dynamics of the context-specific translation arrest by chloramphenicol and linezolid. Nature Chemical Biology, 2020, 16, 310–317. doi: 10.1038/s41589-019-0423-2
  270. Melms, J.C.; Vallabhaneni, S.; Mills, C.E.; Yapp, C.; Chen, J.-Y.; Morelli, E.; Waszyk, P.; Kumar, S.; Deming, D.; Moret, N.; Rodriguez, S.; Subramanian, K.; Rogava, M.; Cartwright, A.N.R.; Luoma, A.; Mei, S.; Brinker, T.J.; Miller, D.M.; Spektor, A.; Schadendorf, D.; Riggi, N.; Wucherpfennig, K.W.; Sorger, P.K.; Izar, B. Inhibition of Haspin kinase promotes cell-intrinsic and extrinsic anti-tumor activity. Cancer Research, 2020, 80(4), 798–810. doi: 10.1158/0008-5472.CAN-19-2330
  271. Zhang, C.T.; Liu, Y.; Wang, X.; Wang, X.; Kolle, S.; Balazs, A.C.; Aizenberg, J. Patterning non-equilibrium morphologies in stimuli-responsive gels through topographical confinement. Soft Matter, 2020, 16(6), 1463–1472. doi: 10.1039/c9sm02221j
  272. Wang, A.; Kolhe, J.A.; Gioacchini, N.; Baade, I.; Brieher, W.M.; Peterson, C.L.; Freeman, B.C. Mechanism of Long-Range Chromosome Motion Triggered by Gene Activation. Developmental Cell, 2020, 52(3), 309–320.e5. doi: 10.1016/j.devcel.2019.12.007
  273. Solbak, S.M.Ø.; Zang, J.; Narayanan, D.; Høj, Jakobsen, L.; Bucciarelli, S.; Softley, C.; Meier, S.; Langkilde, A.E.; Gotfredsen, C.H.; Sattler, M.; Bach, A. Developing Inhibitors of the p47phox-p22phox Protein-Protein Interaction by Fragment-Based Drug Discovery. Journal of Medicinal Chemistry, 2020, 63(3), 1156–1177. doi: 10.1021/acs.jmedchem.9b01492
  274. de Oliveira, J.K.; Ueda-Nakamura, T.; Corrêa, A.G.; Petrilli, R.; Lopez, R.F.V.; Nakamura, C.V.; Auzely-Velty, R. Liposome-based nanocarrier loaded with a new quinoxaline derivative for the treatment of cutaneous leishmaniasis. Materials Science and Engineering: C, 2020, 110, 110720. doi: 10.1016/j.msec.2020.110720
  275. Garafutdinov, R.R.; Sakhabutdinova, A.R.; Kupryushkin, M.S.; Pyshnyi, D.V. Data on multimerization efficiency for short linear DNA templates and phosphoryl guanidine primers during isothermal amplification with Bst exo- DNA polymerase. Data in Brief, 2020, 29, 105188. doi: 10.1016/j.dib.2020.105188
  276. Sheykhzadeh, S.; Luo, M.; Peng, B.; White, J.; Abdalla, Y.; Tang, T.; Mäkilä, E.; Voelcker, N.H.; Tong, W.Y. Transferrin-targeted porous silicon nanoparticles reduce glioblastoma cell migration across tight extracellular space. Scientific Reports, 2020, 10, 2320. doi: 10.1038/s41598-020-59146-5
  277. Song, P.; Shen, J.; Ye, D.; Dong, B.; Wang, F.; Pei, H.; Wang, J.; Shi, J.; Wang, L.; Xue, W.; Huang, Y.; Huang, G.; Zuo, X.; Fan, C. Programming bulk enzyme heterojunctions for biosensor development with tetrahedral DNA framework. Nature Communications, 2020, 11, 838. doi: 10.1038/s41467-020-14664-8
  278. Romanova, Y.; Laikov, A.; Markelova, M.; Khadiullina, R.; Makseev, A.; Hasanova, M.; Rizvanov, A.; Khaiboullina, S.; Salafutdinov, I. Proteomic Analysis of Human Serum from Patients with Chronic Kidney Disease. Biomolecules, 2020, 10(2), 257. doi: 10.3390/biom10020257
  279. Sundin, C.; Zetterström, C.E.; Vo, D.D.; Brkljača, R.; Urban, S.; Elofsson, M. Exploring resveratrol dimers as virulence blocking agents – Attenuation of type III secretion in Yersinia pseudotuberculosis and Pseudomonas aeruginosa. Scientific Reports, 2020, 10, 2103. doi: 10.1038/s41598-020-58872-0
  280. Tesarova, B.; Dostalova, S.; Smidova, V.; Goliasova, Z.; Skubalova, Z.; Michalkova, H.; Hynek, D.; Michalek, P.; Polanska, H.; Vaculovicova, M.; Hacek, J.; Eckschlager, T.; Stiborova, M.; Pires, A.S.; Neves, A.R.M.; Abrantes, A.M.; Rodrigues, T.; Matafome, P.; Botelho, M.F.; Teixeira, P.; Mendes, F.; Heger, Z. Surface-PASylation of ferritin to form stealth nanovehicles enhances in vivo therapeutic performance of encapsulated ellipticine. Applied Materials Today, 2020, 18, 100501. doi: 10.1016/j.apmt.2019.100501
  281. He, H.; Sofman, M.; Wang, A.J.-S.; Ahrens, C.C.; Wang, W.; Griffith, L.G.; Hammond, P.T. Engineering Helical Modular Polypeptide-Based Hydrogels as Synthetic Extracellular Matrices for Cell Culture. Biomacromolecules, 2020, 21(2), 566–580. doi: 10.1021/acs.biomac.9b01297
  282. Yong, K.; Yuen, D.; Chen, M.Z.; Johnston, A.P.R. Engineering the Orientation, Density and Flexibility of Single Domain Antibodies on Nanoparticles to Improve Cell Targeting. ACS Applied Materials & Interfaces, 2020, 12(5), 5593–5600. doi: 10.1021/acsami.9b20993
  283. Novoselova, M.V.; Loh, H.M.; Trushina, D.B.; Ketkar, A.; Abakumova, T.O.; Zatsepin, T.S.; Kakran, M.; Brzozowska, A.M.; Lau, H.H.; Gorin, D.A.; Antipina, M.N.; Anna, B. Biodegradable Polymeric Multilayer Capsules for Therapy of Lung Cancer. ACS Applied Materials & Interfaces, 2020, 12(5), 5610–5623. doi: 10.1021/acsami.9b21381
  284. Joseph, M.K.; Islam, M.S.; Reineke, J.; Hildreth, M.; Woyengo, T.; Pillatzki, A.; Baride, A.; Perumal, O. Intraductal Drug Delivery to the Breast: Effect of Particle size and Formulation on Breast Duct and Lymph Node Retention. Molecular Pharmaceutics, 2020, 17(2), 441–452. doi: 10.1021/acs.molpharmaceut.9b00879
  285. Song, L.; Chen, Y.; Ding, J.; Wu, H.; Zhang, W.; Ma, M.; Zang, F.; Wang, Z.; Gu, N.; Zhang, Y. Rituximab conjugated iron oxide nanoparticles for targeted imaging and enhanced treatment against CD20-positive lymphoma. Journal of Materials Chemistry B, 2020, 8(5), 895&ndasH,907. doi: 10.1039/C9TB02521A
  286. Adams, M.R.; Moody, C.T.; Sollinger, J.L.; Brudno, Y. Extracellular Matrix-Anchored Click Motifs for Specific Tissue Targeting. Molecular Pharmaceutics, 2020, 17(2), 392–403. doi: 10.1021/acs.molpharmaceut.9b00589
  287. Qiao, H.; Wei, Z.; Wang, Y.; Hu, N.; Sun, S.; Bai, J.; Fang, L.; Wang, Z. Focused characteristics and effects of light reflected from spherical lipid membrane of giant unilamellar vesicles. Colloids and Surfaces, B: Biointerfaces, 2020, 189, 110828. doi: 10.1016/j.colsurfb.2020.110828
  288. Gui, Z.; Zhu, J.; Ye, S.; Ye, J.; Chen, J.; Ling, Y.; Cai, X.; Cao, P.; He, Z.; Hu, C. Prolonged melittin release from polyelectrolyte-based nanocomplexes decreases acute toxicity and improves blood glycemic control in a mouse model of type II diabetes. International Journal of Pharmaceutics, 2020, 577, 119071. doi: 10.1016/j.ijpharm.2020.119071
  289. Yang, Y.; Long, Y.; Wang, Y.; Ren, K.; Li, M.; Zhang, Z.; Xiang, B.; He, Q. Enhanced anti-tumor and anti-metastasis therapy for triple negative breast cancer by CD44 receptor-targeted hybrid self-delivery micelles. International Journal of Pharmaceutics, 2020, 577, 119085. doi: 10.1016/j.ijpharm.2020.119085
  290. Garafutdinov, R.R.; Gilvanov, A.R.; Sakhabutdinova, A.R. The Influence of Reaction Conditions on DNA Multimerization During Isothermal Amplification with Bst exo– DNA Polymerase. Applied Biochemistry and Biotechnology, 2020, 190(2), 758–771. doi: 10.1007/s12010-019-03127-6
  291. Chernikova, E.Y.; Ruleva, A.Y.; Tsvetkov, V.B.; Fedorov, Y.V.; Novikov, V.V.; Aliyeu, T.M.; Pavlov, A.A:; Shepel, N.; Fedorova, O. Cucurbit[7]uril-driven modulation of ligand–DNA interactions by ternary assembly. Organic & Biomolecular Chemistry, 2020, 18(4), 755–766. doi: 10.1039/c9ob02543j
  292. Mahmoud, A.M.; Morrow, J.P.; Pizzi, D.; Nanayakkara, S.; Davis, T.P.; Saito, K.; Kempe, K. Nonionic Water-Soluble and Cytocompatible Poly(amide acrylate)s. Macromolecules, 2020, 53(2), 693–701. doi: 10.1021/acs.macromol.9b02267
  293. Nam, J.; Lim, H.-K.; Kim, N.H.; Park, J.K.; Kang, E.S.; Kim, Y.-T.; Heo, C.; Lee, O.-S.; Kim, S.-G.; Yun, W.S.; Suh, M.; Kim, Y.H. Supramolecular Peptide Hydrogel-Based Soft Neural Interface Augments Brain Signals through Three-Dimensional Electrical Network. ACS Nano, 2020, 14(1), 664–675. doi: 10.1021/acsnano.9b07396
  294. Ast, J.; Arvaniti, A.; Fine, N.H.F.; Nasteska, D.; Ashford, F.B.; Stamataki, Z.; Koszegi, Z.; Bacon, A.; Jones, B.J.; Lucey, M.A.; Sasaki, S.; Brierley, D.I.; Hastoy, B.; Tomas, A.; D'Agostino, G.; Reimann, F.; Lynn, F.C.; Reissaus, C.A.; Linnemann, A.K.; D'Este, E.; Calebiro, D.; Trapp, S.; Johnsson, K.; Podewin, T.; Broichhagen, J.; Hodson, D.J. Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics. Nature Communications, 2020, 11, 467. doi: 10.1038/s41467-020-14309-w
  295. Samaridou, E.; Kalamidas, N.; Santalices, I.; Crecente-Campo, J.; Alonso, M.J. Tuning the PEG surface density of the PEG-PGA enveloped Octaarginine-peptide Nanocomplexes. Drug Delivery and Translational Research, 2020, 10(1), 241–258. doi: 10.1007/s13346-019-00678-3
  296. Antipova, O.M.; Solius, G.M.; Panteleev, D.Y.; Reshetnikov, R.V. Interaction between thrombin and oligonucleotide RA36 is a two-stage process. Biochemical and Biophysical Research Communications, 2020, 522(4), 1037–1040. doi: 10.1016/j.bbrc.2019.11.190
  297. Baksheeva, V.E.; Nemashkalova, E.L.; Firsov, A.M.; Zalevsky, A.O.; Vladimirov, V.I.; Tikhomirova, N.K.; Philippov, P.P.; Zamyatnin, A.A.; Zinchenko, D.V.; Antonenko, Y.N.; Permyakov, S.E.; Zernii, E.Y. Membrane Binding of Neuronal Calcium Sensor-1: Highly Specific Interaction with Phosphatidylinositol-3-Phosphate. Biomolecules, 2020, 10, 164. doi: 10.3390/biom10020164
  298. Nomoto, T.; Inoue, Y.; Yao, Y.; Suzuki, M.; Kanamori, K.; Takemoto, H.; Matsui, M.; Tomoda, K.; Nishiyama, N. Poly(vinyl alcohol) boosting therapeutic potential of p-boronophenylalanine in neutron capture therapy by modulating metabolism. Science Advances, 2020, 6(4), eaaz1722. doi: 10.1126/sciadv.aaz1722
  299. Takemoto, H.; Inaba, T.; Nomoto, T.; Matsui, M.; Liu, X.; Toyoda, M.; Honda, Y.; Taniwaki, K.; Yamada, N.; Kim, J.; Tomoda, K.; Nishiyama, N. Polymeric modification of gemcitabine via cyclic acetal linkage for enhanced anticancer potency with negligible side effects. Biomaterials, 2020, 235, 119804. doi: 10.1016/j.biomaterials.2020.119804
  300. Kim, E.-S.; Kim, D.; Nyberg, S.; Poma, A.; Cecchin, D.; Jain, S.A.; Kim, K.-A.; Shin, Y.-J.; Kim, E.-H.; Kim, M.; Baek, S.-H.; Kim, J.-K.; Doeppner, T.R.; Ali, A.; Redgrave, J.; Battaglia, G.; Majid, A.; Bae, O.-N. LRP-1 functionalized polymersomes enhance the efficacy of carnosine in experimental stroke. Scientific Reports, 2020, 10, 699. doi: 10.1038/s41598-020-57685-5
  301. Korevaar, P.A.; Kaplan, C.N.; Grinthal, A.; Rust, R.M.; Aizenberg, J. Non-equilibrium signal integration in hydrogels. Nature Communications, 2020, 11, 386. doi: 10.1038/s41467-019-14114-0
  302. Pinals, R.L.; Yang, D.; Lui, A.; Cao, W.; Landry, M.P. Corona exchange dynamics on carbon nanotubes by multiplexed fluorescence monitoring. Journal of the American Chemical Society, 2020, 142(3), 1254–1264. doi: 10.1021/jacs.9b09617
  303. Huang, C.-Y.; Yagüe-Capilla, M.; González-Pacanowska, D.; Chang, Z.-F. Quantitation of deoxynucleoside triphosphates by click reactions. Scientific Reports, 2020, 10, 611. doi: 10.1038/s41598-020-57463-3
  304. Naidu, P.S.R.; Denham, E.; Bartlett, C.A.; McGonigle, T.; Taylor, N.L.; Norret, M.; Smith, N.M.; Dunlop, S.A.; Iyer, K.S.; Fitzgerald, M. Protein corona formation moderates the release kinetics of ion channel antagonists from transferrin-functionalized polymeric nanoparticles. RSC Advances, 2020, 10(5), 2856–2869. doi: 10.1039/c9ra09523c
  305. Choi, H.; Hwang, B.W.; Park, K.M.; Kim, K.S.; Hahn, S.K. Degradable Nanomotors Using Platinum Deposited Complex of Calcium Carbonate and Hyaluronate Nanogels for Targeted Drug Delivery. Particle & Particle Systems Characterization, 2020, 37(1), 1900418. doi: 10.1002/ppsc.201900418
  306. Cherkasov, V.R.; Mochalova, E.N.; Babenyshev, A.V.; Rozenberg, J.M.; Sokolov, I.L.; Nikitin, M.P. Antibody-Directed Metal-Organic Framework Nanoparticles for Targeted Drug Delivery. Acta Biomaterialia, 2020, 103, 223–236. doi: 10.1016/j.actbio.2019.12.012
  307. Zhang, P.; Gao, Z.; Cui, J.; Hao, J. Dual-Stimuli-Responsive Polypeptide Nanoparticles for Photothermal and Photodynamic Therapy. ACS Applied Bio Materials, 2020, 3(1), 561–569. doi: 10.1021/acsabm.9b00964
  308. Sameshima, T.; Yukawa, T.; Hirozane, Y.; Yoshikawa, M.; Katoh, T.; Hara, H.; Yogo, T.; Miyahisa, I.; Okuda, T.; Miyamoto, M.; Naven, R. Small-scale panel comprising diverse gene family targets to evaluate compound promiscuity. Chemical Research in Toxicology, 2020, 33(1), 154–161. doi: 10.1021/acs.chemrestox.9b00128
  309. Long, M.J.C; Zhao, Y.; Aye, Y. Clofarabine Commandeers the RNR-α-ZRANB3 Nuclear Signaling Axis. Cell Chemical Biology, 2020, 27(1), 122–133.e5. doi: 10.1016/j.chembiol.2019.11.012
  310. Li, Z.; Pinch, B.J.; Olson, C.M.; Donovan, K.A.; Nowak, R.P.; Mills, C.E.; Scott, D.A.; Doctor, Z.M.; Eleuteri, N.A.; Chung, M.; Sorger, P.K.; Fischer, E.S.; Gray, N.S. Development and Characterization of a Wee1 Kinase Degrader. Cell Chemical Biology, 2020, 27(1), 57–65.e9. doi: 10.1016/j.chembiol.2019.10.013
  311. Imlimthan, S.; Correia, A.; Figueiredo, P.; Lintinen, K.; Balasubramanian, V.; Airaksinen, A.J.; Kostiainen, M.A.; Santos, H.A.; Sarparanta, M. Systematic In Vitro Biocompatibility Studies of Multimodal Cellulose Nanocrystal and Lignin Nanoparticles. Journal of Biomedical Materials Research. Part A, 2020, 108(3), 770–783. doi: 10.1002/jbm.a.36856
  312. Lu, H.; Su, J.; Mamdooh, R.; Li, Y.; Stenzel, M.H. Cellular Uptake of Gold Nanoparticles and Their Movement in 3D Multicellular Tumor Spheroids: Effect of Molecular Weight and Grafting Density of Poly(2-hydroxyl ethyl acrylate). Macromolecular Bioscience, 2020, 20(1), e1900221. doi: 10.1002/mabi.201900221
  313. Baniulis, D.; Sirgėdienė, M.; Haimi, P.; Tamošiūnė, I.; Danusevičius, D. Constitutive and Cold Acclimation-Regulated Protein Expression Profiles of Scots Pine Seedlings Reveal Potential for Adaptive Capacity of Geographically Distant Populations. Forests, 2020, 11(1), 89. doi: 10.3390/f11010089
  314. Steadman, P.E.; Xia, F.; Ahmed, M.; Mocle, A.J.; Penning, A.R.A.; Geraghty, A.C.; Steenland, H.W.; Monje, M.; Josselyn, S.A.; Frankland, P.W. Disruption of Oligodendrogenesis Impairs Memory Consolidation in Adult Mice. Neuron, 2020, 105(1), 150–164.e6. doi: 10.1016/j.neuron.2019.10.013
  315. Holla, S.; Dhakshnamoorthy, J.; Folco, H.D.; Balachandran, V.; Xiao, H.; Sun, L.-L.; Wheeler, D.; Zofall, M.; Grewal, S.I.S. Positioning Heterochromatin at the Nuclear Periphery Suppresses Histone Turnover to Promote Epigenetic Inheritance. Cell, 2020, 180(1), 150–164.e15. doi: 10.1016/j.cell.2019.12.004
  316. Schiapparelli, P.; Zhang, P.; Lara-Velazquez, M.; Guerrero-Cazares, H.; Lin, R.; Su, H.; Chakroun, R.W.; Tusa, M.; Quiñones-Hinojosa, A.; Cui, H. Self-assembling and self-formulating prodrug hydrogelator extends survival in a glioblastoma resection and recurrence model. Journal of Controlled Release, 2020, 319, 311–321. doi: 10.1016/j.jconrel.2020.01.003
  317. Fliervoet, L.A.L.; Lisitsyna, E.S.; Durandin, N.A.; Kotsis, I.; Maas-Bakker, R.F.M.; Yliperttula, M.; Hennink, W.E.; Vuorimaa-Laukkanen, E.; Vermonden, T. Structure and dynamics of thermosensitive pDNA polyplexes studied by time-resolved fluorescence spectroscopy. Biomacromolecules, 2020, 21(1), 73–88. doi: 10.1021/acs.biomac.9b00896
  318. Han, W.; Shi, L.; Xie, B.; Wan, J.; Ren, L.; Wang, Y.; Chen, X.; Wang, H. Supramolecular Engineering of Molecular Inhibitors in an Adaptive Cytotoxic Nanoparticle for Synergistic Cancer Therapy. ACS Applied Materials & Interfaces, 2020, 12(1), 1707–1720. doi: 10.1021/acsami.9b20178
  319. Pola, R.; Böhmová, E.; Filipová, M.; Pechar, M.; Pankrác, J.; Větvička, D.; Olejár, T.; Kabešová, M.; Poučková, P.; Šefc, L.; Zábrodský, M.; Janoušková, O.; Bouček, J.; Etrych, T. Targeted Polymer-Based Probes for Fluorescence Guided Visualization and Potential Surgery of EGFR-Positive Head-and-Neck Tumors. Pharmaceutics, 2020, 12, 31. doi: 10.3390/pharmaceutics12010031
  320. Ni, R.; Song, G.; Fu, X.; Song, R.; Li, L.; Pu, W.; Gao, J.; Hu, J.; Liu, Q.; He, F.; Zhang, D.; Huang, G. Reactive oxygen species-responsive dexamethasone-loaded nanoparticles for targeted treatment of rheumatoid arthritis via suppressing the iRhom2/TNF-α/BAFF signaling pathway. Biomaterials, 2020, 232, 119730. doi: 10.1016/j.biomaterials.2019.119730
  321. Radford, D.C.; Yang, J.; Doan, M.C.; Li, L.; Dixon, A.S.; Owen, S.C.; Kopeček, J. Multivalent HER2-binding polymer conjugates facilitate rapid endocytosis and enhance intracellular drug delivery. Journal of Controlled Release, 2020, 319, 285–299. doi: 10.1016/j.jconrel.2019.12.049
  322. Zhao, Meng and Börner, Richard and Sigel, Roland K. O. and Freisinger, Eva. Site-Specific Dual-Color Labeling of Long RNAs. Methods in Molecular Biology, 2020, 2106, 253–270. doi: 10.1007/978-1-0716-0231-7_16
  323. Taghian, T.; Metelev, V.G.; Zhang, S.; Bogdanov, A.A. Imaging NF-κB activity in a murine model of early stage diabetes. FASEB Journal, 2020, 34(1), 1198–1210. doi: 10.1096/fj.201801147r
  324. Wang, Y.; Dattmore, D.A.; Wang, W:; Pohnert, G.; Wolfram, S.; Zhang, J.; Yang, R.; Decker, E.A.; Lee, K.S.S.; Zhang, G. trans, trans-2,4-decadienal, a lipid peroxidation product, induces inflammatory responses via Hsp90- or 14–3-3ζ-dependent mechanisms. Journal of Nutritional Biochemistry, 2020, 76, 108286. doi: 10.1016/j.jnutbio.2019.108286
  325. Nishimura, T.; Mitsunaga, M.; Ito, K.; Kobayashi, H.; Saruta, M. Cancer neovasculature-targeted near-infrared photoimmunotherapy (NIR-PIT) for gastric cancer: different mechanisms of phototoxicity compared to cell membrane-targeted NIR-PIT. Gastric Cancer, 2020, 23(1), 82–94. doi: 10.1007/s10120-019-00988-y
  326. Kirectepe Aydin, A.; Özgüler, Y.; Uçar, D.; Kasap, M.; Akpınar, G.; Seyahi, E.; Tahir Turanli, E. Peripheral blood mononuclear cell proteome profile in Behçet's syndrome. Rheumatology International, 2020, 40(1), 65–74. doi: 10.1007/s00296-019-04417-2
  327. Kim, H.; Han, J.; Park, J.-H. Cyclodextrin polymer improves atherosclerosis therapy and reduces ototoxicity. Journal of Controlled Release, 2020, 319, 77–86. doi: 10.1016/j.jconrel.2019.12.021
  328. He, Z.; Nie, T.; Hu, Y.; Zhou, Y.; Zhu, J.; Liu, Z.; Liu, L.; Leong, K.W.; Chen, Y.; Mao, H.-Q. A polyphenol-metal nanoparticle platform for tunable release of liraglutide to improve blood glycemic control and reduce cardiovascular complications in a mouse model of type II diabetes. Journal of Controlled Release, 2020, 318, 86–97. doi: 10.1016/j.jconrel.2019.12.014
  329. Zhang, R.; Liu, R.; Liu, C.; Pan, L.; Qi, Y.; Cheng, J.; Guo, J.; Jia, Y.; Ding, J.; Zhang, J.; Hu, H. A pH/ROS dual-responsive and targeting nanotherapy for vascular inflammatory diseases. Biomaterials, 2020, 230, 119605. doi: 10.1016/j.biomaterials.2019.119605
  330. Ereskovsky, A.V.; Tokina, D.B.; Saidov, D.M.; Baghdiguian, S.; Le Goff, E.; Lavrov, A.I. Transdifferentiation and mesenchymal-to-epithelial transition during regeneration in Demospongiae (Porifera). Journal of Experimental Zoology. Part B, 2020, 334(1), 37–58. doi: 10.1002/jez.b.22919
  331. Anani, T.; Brannen, A.; Panizzi, P.; Duin, E.C.; David, A.E. Quantitative, real-time in vivo tracking of magnetic nanoparticles using multispectral optoacoustic tomography (MSOT) imaging. Journal of Pharmaceutical and Biomedical Analysis, 2020, 178, 112951. doi: 10.1016/j.jpba.2019.112951
  332. Ji, W.; Smith, P.N.; Koepsel, R.R.; Andersen, J.D.; Baker, S.L.; Zhang, L.; Carmali, S.; Myerson, J.W.; Muzykantov, V.; Russell, A.J. Erythrocytes as Carriers of Immunoglobulin-Based Therapeutics. Acta Biomaterialia, 2020, 101, 422–435. doi: 10.1016/j.actbio.2019.10.027
  333. Guenter, R.; Aweda, T.; Carmona Matos, D.M.; Jang, S.; Whitt, J.; Cheng, Y.-Q.; Liu, X.M.; Chen, H.; Lapi, S.E.; Jaskula-Sztul, R. Overexpression of somatostatin receptor type 2 in neuroendocrine tumors for improved Ga68-DOTATATE imaging and treatment. Surgery, 2020, 167(1), 189–196. doi: 10.1016/j.surg.2019.05.092
  334. Cliff, L.; Chadda, R.; Robertson, J.L. Occupancy distributions of membrane proteins in heterogeneous liposome populations. BBA Biomembranes, 2020, 1862(1), 183033. doi: 10.1016/j.bbamem.2019.183033
  335. Garafutdinov, R.R.; Sakhabutdinova, A.R.; Kupryushkin, M.S.; Pyshnyi, D.V. Prevention of DNA multimerization using phosphoryl guanidine primers during isothermal amplification with Bst exo- DNA polymerase. Biochimie, 2020, 168, 259–267. doi: 10.1016/j.biochi.2019.11.013
  336. Faidra Angelerou, M.G.; Markus, R.; Paraskevopoulou, V.; Foralosso, R.; Clarke, P.; Alvarez, C.V.; Chenlo, M.; Johnson, L.; Rutland, C.; Allen, S.; Brasnett, C.; Seddon, A.; Zelzer, M.; Marlow, M. Mechanistic investigations into the encapsulation and release of small molecules and proteins from a supramolecular nucleoside gel in vitro and in vivo. Journal of Controlled Release, 2020, 317, 118–129. doi: 10.1016/j.jconrel.2019.10.011
  337. Umakoshi, T.; Fukuda, S.; Iino, R.; Uchihashi, T.; Ando, T. High-speed near-field fluorescence microscopy combined with high-speed atomic force microscopy for biological studies. Biochimica et Biophysica Acta, 2020, 1864(2), 129325. doi: 10.1016/j.bbagen.2019.03.011
  338. Stokol, T.; Wan, C.; Blakely, R.; Bellat, V.; Law, B. Aldoxorubicin-loaded nanofibers are cytotoxic for canine mammary carcinoma and osteosarcoma cell lines in vitro: A short communication. Research in Veterinary Science, 2020, 128, 86–89. doi: 10.1016/j.rvsc.2019.11.003
  339. Sarparanta, M.; Pourat, J.; Carnazza, K.E.; Tang, J.; Paknejad, N.; Reiner, T.; Kostiainen, M.A.; Lewis, J.S. Multimodality labeling strategies for the investigation of nanocrystalline cellulose biodistribution in a mouse model of breast cancer. Nuclear Medicine and Biology, 2020, 80–81, 1–12. doi: 10.1016/j.nucmedbio.2019.11.002
  340. Hyun, H.; Yoo, Y.; Kim, S.Y.; Ko, H.S.; Chun, H.J.; Yang, D.H. Optimization of cRGDfK Ligand Concentration on Polymeric Nanoparticles to Maximize Cancer Targeting. Journal of Industrial and Engineering Chemistry, 2020, 81, 178–184. doi: 10.1016/j.jiec.2019.09.006
  341. Aydemir, M. Triplet-Triplet Annihilation Based Energy Upconversion Mechanism: Cyanine7 Dye Doped with Super Yellow and Rubrene Hosts. Sakarya University Journal of Science, 2020, 24(1), 55–59. doi: 10.16984/saufenbilder.538797
  342. Jiang, H.; D’Agostino, G.D.; Cole, P.A.; Dempsey, D.R. Selective protein N-terminal labeling with N-hydroxysuccinimide esters. Methods in enzymology, 2020, 639, 333-353. doi: 10.1016/bs.mie.2020.04.018
  343. Moody, C.T.; Palvai, S.; Brudno, Y. Click Cross-linking Improves Retention and Targeting of Refillable Alginate Depots. Acta Biomaterialia, 2020, 112, 112-121. doi: 10.1016/j.actbio.2020.05.033
  344. Jeon, M.; Lin, G.; Stephen, Z.R.; Vechey, J.E.; Singh, M.; Revia, R.; Newman, A.H.; Martinez, D.; Zhang, M. Cocaine Analogue Conjugated Magnetic Nanoparticles for Labeling and Imaging Dopaminergic Neurons. Biomaterials Science, 2020, 8(15), 4166-4175. doi: 10.1039/d0bm00546k
  345. Barberio, A.E.; Smith, S.G.; Correa, S.; Nguyen, C.; Nhan, B.; Melo, M.; Tokatlian, T.; Suh, H.; Irvine, D.J.; Hammond, P.T. Cancer Cell Coating Nanoparticles for Optimal Tumor-Specific Cytokine Delivery. ACS Nano, 2020, 14(9), 11238-11253. doi: 10.1021/acsnano.0c03109
  346. Yavitt, F.M.; Brown, T.E.; Hushka, E.A.; Brown, M.E.; Gjorevski, N.; Dempsey, P.J.; Lutolf, M.P.; Anseth, K.S. The effect of thiol structure on allyl sulfide photodegradable hydrogels and their application as a degradable scaffold for organoid passaging. Advanced materials (Deerfield Beach, Fla.), 2020, 32(30), e1905366. doi: 10.1002/adma.201905366
  347. Gao, C.F.; Wisniewski, L.; Liu, Y.; Staal, B.; Beddows, I.; Plenker, D.; Aldakkak, M.; Hall, J.; Barnett, D.; Gouda, M.K.; Allen, P.; Drake, R.; Zureikat, A.; Huang, Y.; Evans, D.; Singhi, A.; Brand, R.E.; Tuveson, D.A.; Tsai, S.; Haab, B.B. Detection of Chemotherapy-Resistant Pancreatic Cancer Using a Glycan Biomarker, sTRA. Clinical Cancer Research, 2020, 27(1), 226-236. doi: 10.1158/1078-0432.CCR-20-2475
  348. Stevens, D.M.; Adiseshaiah, P.; Dasa, S.S.K.; Potter, T.M.; Skoczen, S.L.; Snapp, K.S.; Cedrone, E.; Patel, N.; Busman-Sahay, K.; Rosen, E.P.; Sykes, C.; Cottrell, M.; Dobrovolskaia, M.A.; Estes, J.D.; Kashuba, A.D.M.; Stern, S.T. Application of a Scavenger Receptor A1 Targeted Polymeric Prodrug Platform for Lymphatic Drug Delivery in HIV. Molecular Pharmaceutics, 2020, 17(10), 3794-3812. doi: 10.1021/acs.molpharmaceut.0c00562
  349. Huang, X.; Williams, J.Z.; Chang, R.; Li, Z.; Burnett, C.E.; Hernandez-Lopez, R.; Setiady, I.; Gai, E.; Patterson, D.M.; Yu, W.; Roybal, K.T.; Lim, W.A.; Desai, T.A. DNA scaffolds enable efficient and tunable functionalization of biomaterials for immune cell modulation. Nature Nanotechnology, 2020, 16(2), 214-223. doi: 10.1038/s41565-020-00813-z
  350. Liu, Y.; Ferguson, F.M.; Li, L.; Kuljanin, M.; Mills, C.E.; Subramanian, K.; Harshbarger, W.; Gondi, S.; Wang, J.; Sorger, P.K.; Mancias, J.D.; Gray, N.S.; Westover, K.D. Chemical Biology Toolkit for DCLK1 Reveals Connection to RNA Processing. Cell Chemical Biology, 2020, 27(10), 1229-1240.e4. doi: 10.1016/j.chembiol.2020.07.011
  351. Park, J.; Chariou, P.L.; Steinmetz, N.F. Site-Specific Antibody Conjugation Strategy to Functionalize Virus- Based Nanoparticles. Bioconjugate Chemistry, 2020, 31(5), 1408-1416. doi: 10.1021/acs.bioconjchem.0c00118
  352. Shukla, S.; Wang, C.; Beiss, V.; Cai, H.; Washington, T.; Murray, A.A.; Gong, X.; Zhao, Z.; Masarapu, H.; Zlotnick, A.; Fiering, S.; Steinmetz, N.F. The unique potency of Cowpea mosaic virus (CPMV) in situ cancer vaccine. Biomaterials Science, 2020, 8(19), 5489-5503. doi: 10.1039/d0bm01219j
  353. Poganik, J.R.; Van Hall-Beauvais, A.K.; Long, M.J.C.; Disare, M.T.; Zhao, Y.; Aye, Y. The mRNA-Binding Protein HuR Is a Kinetically-Privileged Electrophile Sensor. Helvetica Chimica Acta, 2020, 103(5), e2000041. doi: 10.1002/hlca.202000041
  354. Gupta, V.; Gupta, I.; Park, J.; Bram, Y.; Schwartz, R.E. Hedgehog Signaling Demarcates a Niche of Fibrogenic Peribiliary Mesenchymal Cells. Gastroenterology, 2020, 159(2), 624-638.e9. doi: 10.1053/j.gastro.2020.03.075
  355. D'Orazi, F.D.; Suzuki, S.C.; Darling, N.; Wong, R.O.; Yoshimatsu, T. Conditional and biased regeneration of cone photoreceptor types in the zebrafish retina. The Journal of Comparative Neurology, 2020, 528(17), 2816-2830. doi: 10.1002/cne.24933
  356. Sturm, M.B.; Joshi, B.P.; Owens, S.R.; Seibel, E.J.; Wang, T.D. Multiplexed Imaging Strategy to Distinguish Indeterminant Biliary Strictures: An Ex Vivo Study. World journal of gastroenterology, hepatology and endoscopy, 2020, 3(3), WJGHE-1-122. doi: 10.47690/wjghe.2020.3303
  357. Zhu, M.; Lu, D.; Lian, Q.; Wu, S.; Wang, W.; Lyon, L.A.; Wang, W.; Bártolo, P.; Dickinson, M.; Saunders, B.R. Highly swelling pH-responsive microgels for dual mode near infra-red fluorescence reporting and imaging. Nanoscale Advances, 2020, 2(9), 4261-4271. doi: 10.1039/d0na00581a
  358. Wu, C.; Boisclair Lachance, J.-F.; Ludwig, M.Z.; Rebay, I. A context-dependent bifurcation in the Pointed transcriptional effector network contributes specificity and robustness to retinal cell fate acquisition. PLOS Genetics, 2020, 16(11), e1009216. doi: 10.1371/journal.pgen.1009216
  359. Karyagina, T.S.; Ulasov, A.V.; Slastnikova, T.A.; Rosenkranz, A.A.; Lupanova, T.N.; Khramtsov, Y.V.; Georgiev, G.P.; Sobolev, A.S. Targeted Delivery of 111 In Into the Nuclei of EGFR Overexpressing Cells via Modular Nanotransporters With Anti-EGFR Affibody. Frontiers in Pharmacology, 2020, 11, 176. doi: 10.3389/fphar.2020.00176
  360. Shih, F.-Y.; Jiang, W.-P.; Lin, X.; Kuo, S.-C.; Huang, G.-J.; Hou, Y.-C.; Chang, C.-S.; Liu, Y.; Chiang, Y.-T. A Novel pH-Tunable Secondary Conformation Containing Mixed Micellar System in Anticancer Treatment. Cancers, 2020, 12(2), 503. doi: 10.3390/cancers12020503
  361. Galeev, A.; Suwandi, A.; Bakker, H.; Oktiviyari, A.; Routier, F.H.; Krone, L.; Hensel, M.; Grassl, G.A. Proteoglycan-Dependent Endo-Lysosomal Fusion Affects Intracellular Survival of Salmonella Typhimurium in Epithelial Cells. Frontiers in Immunology, 2020, 11, 731. doi: 10.3389/fimmu.2020.00731
  362. Hsueh, P.-Y.; Ju, Y.; Vega, A.; Edman, M.C.; MacKay, J.A.; Hamm-Alvarez, S.F. A Multivalent ICAM-1 Binding Nanoparticle which Inhibits ICAM-1 and LFA-1 Interaction Represents a New Tool for the Investigation of Autoimmune-Mediated Dry Eye. International Journal of Molecular Sciences, 2020, 21(8), 2758. doi: 10.3390/ijms21082758
  363. Lunin, A.V.; Lizunova, A.A.; Mochalova, E.N.; Yakovtseva, M.N.; Cherkasov, V.R.; Nikitin, M.P.; Kolychev, E.L. Hematite Nanoparticles from Unexpected Reaction of Ferrihydrite with Concentrated Acids for Biomedical Applications. Molecules, 2020, 25(8), 1984. doi: 10.3390/molecules25081984
  364. Summer, D.; Petrik, M.; Mayr, S.; Hermann, M.; Kaeopookum, P.; Pfister, J.; Klingler, M.; Rangger, C.; Haas, H.; Decristoforo, C. Hybrid Imaging Agents for Pretargeting Applications Based on Fusarinine C—Proof of Concept. Molecules, 2020, 25(9), 2123. doi: 10.3390/molecules25092123
  365. Huang, L.; Liao, T.-W.; Wang, J.; Ha, T.; Lilley, D.M.J. Crystal structure and ligand-induced folding of the SAM/SAH riboswitch. Nucleic Acids Research, 2020, 48(13), 7545-7556. doi: 10.1093/nar/gkaa493
  366. Beri, D.; Jakoby, M.; Busko, D.; Richards, B.S.; Turshatov, A. Enhancing Singlet Oxygen Generation in Conjugates of Silicon Nanocrystals and Organic Photosensitizers. Frontiers in Chemistry, 2020, 8, 567. doi: 10.3389/fchem.2020.00567
  367. Krasheninina, O.A.; Fishman, V.S.; Lomzov, A.A.; Ustinov, A.V.; Venyaminova, A.G. Postsynthetic On-Column 2′ Functionalization of RNA by Convenient Versatile Method. International Journal of Molecular Sciences, 2020, 21(14), 5127. doi: 10.3390/ijms21145127
  368. Sohn, B.-K.; Basu, U.; Lee, S.-W.; Cho, H.; Shen, J.; Deshpande, A.; Johnson, L.C.; Das, K.; Patel, S.S.; Kim, H. The dynamic landscape of transcription initiation in yeast mitochondria. Nature Communications, 2020, 11, 4281. doi: 10.1038/s41467-020-17793-2
  369. Libánská, A.; Randárová, E.; Lager, F.; Renault, G.; Scherman, D.; Etrych, T. Polymer Nanomedicines with Ph-Sensitive Release of Dexamethasone for the Localized Treatment of Inflammation. Pharmaceutics, 2020, 12(8), 700. doi: 10.3390/pharmaceutics12080700
  370. Wang, C.; Liu, C.; Wei, Q.; Yang, L.; Yang, P.; Li, Y.; Cheng, Y. S,S-Tetrazine-Based Hydrogels with Visible Light Cleavable Properties for On-Demand Anticancer Drug Delivery. Research, 2020, 2020, 6563091. doi: 10.34133/2020/6563091
  371. Chang, Y.-H.; Duong, D.M.; Goll, J.B.; Wood, D.C.; Jensen, T.L.; Yin, L.; Gelber, C.E.; Seyfried, N.T.; Anderson, E.; Natrajan, M.S.; Rouphael, N.; Johnson, R.A.; Sanz, P.; Mulligan, M.J.; Hoft, D.F. Proteomic Analysis of Human Immune Responses to Live-Attenuated Tularemia Vaccine. Vaccines, 2020, 8(3), 413. doi: 10.3390/vaccines8030413
  372. Zhu, L.; Li, R.; Jiao, S.; Wei, J.; Yan, Y.; Wang, Z.A.; Li, J.; Du, Y. Blood-Brain Barrier Permeable Chitosan Oligosaccharides Interfere with β-Amyloid Aggregation and Alleviate β-Amyloid Protein Mediated Neurotoxicity and Neuroinflammation in a Dose- and Degree of Polymerization-Dependent Manner. Marine Drugs, 2020, 18(10), 488. doi: 10.3390/md18100488
  373. Lobov, A.A.; Yudintceva, N.M.; Mittenberg, A.G.; Shabelnikov, S.V.; Mikhailova, N.A.; Malashicheva, A.B.; Khotin, M.G. Proteomic Profiling of the Human Fetal Multipotent Mesenchymal Stromal Cells Secretome. Molecules, 2020, 25(22), 5283. doi: 10.3390/molecules25225283
  374. Wu, Q.; Higler, R.; Kodger, T.E.; van der Gucht, J. Particle Dynamics in Colloid–Polymer Mixtures with Different Polymer Architectures. ACS Applied Materials & Interfaces, 2020, 12(37), 42041-42047. doi: 10.1021/acsami.0c07153
  375. Wang, F.; Duan, X.; Chen, J.; Gao, Z.; Zhou, J.; Wu, X.; Chang, T.-S.; Lee, M.; Li, G.; Nusrat, A.; Kuick, R.; Appelman, H.D.; Wang, T.D. Integrated Imaging Methodology Detects Claudin-1 Expression in Premalignant Nonpolypoid and Polypoid Colonic Epithelium in Mice. Clinical and Translational Gastroenterology, 2020, 11(1), e00089. doi: 10.14309/ctg.0000000000000089
  376. Leemans, M.; Galicia, C.; Deyaert, E.; Daems, E.; Krause, L.; Paesmans, J.; Pardon, E.; Steyaert, J.; Kortholt, A.; Sobott, F.; Klostermeier, D.; Versées, W. Allosteric modulation of the GTPase activity of a bacterial LRRK2 homolog by conformation-specific Nanobodies. Biochemical Journal, 2020, 477(7), 1203-1218. doi: 10.1042/BCJ20190843
  377. Navdaev, A.V.; Sborgi, L.; Wright, S.D.; Didichenko, S.A. Nascent HDL (High-Density Lipoprotein) Discs Carry Cholesterol to HDL Spheres Effects of HDL Particle Remodeling on Cholesterol Efflux. Arteriosclerosis, Thrombosis, and Vascular Biology, 2020, 40(5), 1182-1194. doi: 10.1161/ATVBAHA.120.313906
  378. Lin, S.-Y.; Yao, B.-Y.; Hu, C.-M.J.; Chen, H.-W. Induction of Robust Immune Responses by CpG-ODN-Loaded Hollow Polymeric Nanoparticles for Antiviral and Vaccine Applications in Chickens. International Journal of Nanomedicine, 2020, 15, 3303-3318. doi: 10.2147/IJN.S241492
  379. Omer, M.; Andersen, V.L.; Nielsen, J.S.; Wengel, J.; Kjems, J. Improved Cancer Targeting by Multimerizing Aptamers on Nanoscaffolds. Molecular Therapy. Nucleic Acids, 2020, 22, 994-1003. doi: 10.1016/j.omtn.2020.10.013

2019

  1. Johnson, A.G.; Lapointe, C.P.; Wang, J.; Corsepius, N.C.; Choi, J.; Fuchs, G.; Puglisi, J.D. RACK1 on and off the ribosome. RNA, 2019, 25(7), 881-895. doi: 10.1261/rna.071217.119
  2. Nixon, B.; De Iuliis, G.N.; Hart, H.M.; Zhou, W.; Mathe, A.; Bernstein, I.R.; Anderson, A.L.; Stanger, S.J.; Skerrett-Byrne, D.A.; Jamaluddin, M.F.B.; Almazi, J.G.; Bromfield, E.G.; Larsen, M.R.; Dun, M.D. Proteomic Profiling of Mouse Epididymosomes Reveals their Contributions to Post-testicular Sperm Maturation. Molecular & Cellular Proteomics, 2019, 18(Suppl 1), S91-S108. doi: 10.1074/mcp.RA118.000946
  3. Galstyan, A.; Markman, J. L.; Shatalova, E. S.; Chiechi, A.; Korman, A. J.; Patil, R.; Klymyshyn, D.; Tourtellotte, W. G.; Israel, L. L.; Braubach, O.; Ljubimov, V. A.; Mashouf, L. A.; Ramesh, A.; Grodzinski, Z. B.; Penichet, M. L.; Black, K. L.; Holler, E.; Sun, T.; Ding, H.; Ljubimov, A. V.; Ljubimova, J. Y. Blood–Brain Barrier Permeable Nano Immunoconjugates Induce Local Immune Responses for Glioma Therapy. Nature Communications, 2019, 10(1), 3850. doi: 10.1038/s41467-019-11719-3
  4. Hinman, S. S.; Wang, Y.; Allbritton, N. L. Photopatterned Membranes and Chemical Gradients Enable Scalable Phenotypic Organization of Primary Human Colon Epithelial Models. Anal Chem, 2019, 91(23), 15240–15247. doi: 10.1021/acs.analchem.9b04217
  5. Blanchard, A.T.; Bazrafshan, A.S.; Yi, J.; Eisman, J.T.; Yehl, K.M.; Bian, T.; Mugler, A.; Salaita, K. Highly Polyvalent DNA Motors Generate 100+ pN of Force via Autochemophoresis. Nano Letters, 2019, 19(10), 6977–6986. doi: 10.1021/acs.nanolett.9b02311
  6. Chikate, T.R.; Tang, L. Tracking and Imaging of Transplanted Stem Cells in Animals. Methods in Molecular Biology, 2019, 2150, 45–56. doi: 10.1007/7651_2019_275
  7. Wang, Z.; Cui, M.; Shah, A.M.; Ye, W.; Tan, W.; Min, Y.-L.; Botten, G.A.; Shelton, J.M.; Liu, N.; Bassel-Duby, R.; Olson, E.N. Mechanistic basis of neonatal heart regeneration revealed by transcriptome and histone modification profiling. Proceedings of the National Academy of Sciences of the U.S.A., 2019, 116(37), 18455–18465. doi: 10.1073/pnas.1905824116
  8. Judd, J.; Lovas, J.; Huang, G.N. Defined factors to reactivate cell cycle activity in adult mouse cardiomyocytes. Scientific Reports, 2019, 9, 18830. doi: 10.1038/s41598-019-55027-8
  9. Bayat, N.; McOrist, N.; Ariotti, N.; Lai, M.; Sia, K.C.; Li, Y.; Grace, J.L.; Quinn, J.F.; Whittaker, M.R.; Kavallaris, M.; Davis, T.P.; Lock, R.B. Thiol-Reactive Star Polymers Functionalized with Short Ethoxy-Containing Moieties Exhibit Enhanced Uptake in Acute Lymphoblastic Leukemia Cells. International Journal of Nanomedicine, 2019, 14, 9795–9808. doi: 10.2147/IJN.S220326
  10. Greene, E.R.; Goodall, E.A.; de la Peña, A.H.; Matyskiela, M.E.; Lander, G.C.; Martin, A. Specific lid-base contacts in the 26s proteasome control the conformational switching required for substrate degradation. eLife, 2019, 8, e49806. doi: 10.7554/eLife.49806
  11. Ferrer-González, E.; Fujita, J.; Yoshizawa, T.; Nelson, J.M.; Pilch, A.J.; Hillman, E.; Ozawa, M.; Kuroda, N.; Al-Tameemi, H.M.; Boyd, J.M.; LaVoie, E.J.; Matsumura, H.; Pilch, Daniel S. Structure-Guided Design of a Fluorescent Probe for the Visualization of FtsZ in Clinically Important Gram-Positive and Gram-Negative Bacterial Pathogens. Scientific Reports, 2019, 9, 20092. doi: 10.1038/s41598-019-56557-x
  12. Katsumata, K.; Ishihara, J.; Fukunaga, K.; Ishihara, A.; Yuba, E.; Budina, E.; Hubbell, J.A. Conferring extracellular matrix affinity enhances local therapeutic efficacy of anti-TNF-α antibody in a murine model of rheumatoid arthritis. Arthritis Research & Therapy, 2019, 21, 298. doi: 10.1186/s13075-019-2075-8
  13. Bowen, C.H.; Reed, T.J.; Sargent, C.J.; Mpamo, B.; Galazka, J.M.; Zhang, F. Seeded Chain-Growth Polymerization of Proteins in Living Bacterial Cells. ACS Synthetic Biology, 2019, 8(12), 2651–2658. doi: 10.1021/acssynbio.9b00362
  14. Sharmah, A.; Kraus, M.; Cutler, S.; Siegel, J.B.; Brady, S.; Guo, T. Toward Development of Fluorescence Quenching-Based Biosensors for Drought Stress in Plants. Analytical Chemistry, 2019, 91(24), 15644–15651. doi: 10.1021/acs.analchem.9b03751
  15. Yin, B.; Chan, C.K.W.; Liu, S.; Hong, H.; Wong, S.H.D.; Lee, L.K.C.; Ho, L.W.C.; Zhang, L.; Leung, K.C.-F.; Choi, P.C.-L.; Bian, L.; Tian, X.Y.; Chan, M.N.; Choi, C.H.J. Intrapulmonary Cellular-Level Distribution of Inhaled Nanoparticles with Defined Functional Groups and Its Correlations with Protein Corona and Inflammatory Response. ACS Nano, 2019, 13(12), 14048–14069. doi: 10.1021/acsnano.9b06424
  16. Taskova, M.; Astakhova, K. Fluorescent Oligonucleotides with Bis(prop-2-yn-1-yloxy)butane-1,3-diol Scaffold Rapidly Detect Disease-Associated Nucleic Acids. Bioconjugate Chemistry, 2019, 30(12), 3007–3012. doi: 10.1021/acs.bioconjchem.9b00746
  17. Morais, C.M.; Cunha, P.P.; Melo, T.; Cardoso, A.M.; Domingues, P.; Domingues, M.R.; Pedroso de Lima, M.C.; Jurado, A.S. Glucosylceramide synthase silencing combined with the receptor tyrosine kinase inhibitor axitinib as a new multimodal strategy for glioblastoma. Human Molecular Genetics, 2019, 28(21), 3664–3679. doi: 10.1093/hmg/ddz152
  18. Jeon, M.; Lin, G.; Stephen, Z.R.; Kato, F.L.; Zhang, M. Paclitaxel-Loaded Iron Oxide Nanoparticles for Targeted Breast Cancer Therapy. Advanced Therapeutics, 2019, 2(12), 1900081. doi: 10.1002/adtp.201900081
  19. Beldman, T.J.; Malinova, T.S.; Desclos, E.; Grootemaat, A.E.; Misiak, A.L.S.; van der Velden, S.; van Roomen, C.P.A.A.; Beckers, L.; van Veen, H.A.; Krawczyk, P.M.; Hoebe, R.A.; Sluimer, J.C.; Neele, A.E.; de Winther, M.P.J.; van der Wel, N.N.; Lutgens, E.; Mulder, W.J.M.; Huveneers, S.; Kluza, E. Nanoparticle-Aided Characterization of Arterial Endothelial Architecture during Atherosclerosis Progression and Metabolic Therapy. ACS Nano, 2019, 13(12), 13759–13774. doi: 10.1021/acsnano.8b08875
  20. Hu, H.; Wang, B.; Lai, C.; Xu, X.; Zhen, Z.; Zhou, H.; Xu, D. iRGD-paclitaxel conjugate nanoparticles for targeted paclitaxel delivery. Drug Development Research, 2019, 80(8), 1080–1088. doi: 10.1002/ddr.21589
  21. Chen, F.; Bai, M.; Cao, X.; Zhao, Y.; Xue, J.; Zhao, Y. Click-encoded rolling FISH for visualizing single-cell RNA polyadenylation and structures. Nucleic Acids Research, 2019, 47(22), e145. doi: 10.1093/nar/gkz852
  22. Hofmann, F.J.; Bodnarchuk, M.; Dirin, D.N.; Vogelsang, J.; Kovalenko, M.V.; Lupton, J.M. Energy transfer from perovskite nanocrystals to dye molecules does not occur by FRET. Nano Letters, 2019, 19(12), 8896–8902. doi: 10.1021/acs.nanolett.9b03779
  23. Jiang, Z.; He, H.; Liu, H.; Thayumanavan, S. Cellular Uptake Evaluation of Amphiphilic Polymer Assemblies: Importance of Interplay between Pharmacological and Genetic Approaches. Biomacromolecules, 2019, 20(12), 4407–4418. doi: 10.1021/acs.biomac.9b01073
  24. Martin, C.; Brachet, G.; Colas, C.; Allard-Vannier, E.; Kizlik-Masson, C.; Esnault, C.; Respaud, R.; Denevault-Sabourin, C.; Chourpa, I.; Gouilleux-Gruart, V.; Viaud-Massuard, M.-C.; Joubert, N. In Vitro Characterization and Stability Profiles of Antibody-Fluorophore Conjugates Derived from Interchain Cysteine Cross-Linking or Lysine Bioconjugation. Pharmaceuticals, 2019, 12(4), 176. doi: 10.3390/ph12040176
  25. Dietl, A.; Winkel, I.; Pietrzyk, G.; Paulus, M.; Bruckmann, A.; Schröder, J.A.; Sossalla, S.; Luchner, A.; Maier, L.S.; Birner, C. Skeletal muscle alterations in tachycardia-induced heart failure are linked to deficient natriuretic peptide signalling and are attenuated by RAS-/NEP-inhibition. PloS One, 2019, 14, e0225937. doi: 10.1371/journal.pone.0225937
  26. Duss, O.; Stepanyuk, G.A.; Puglisi, J.D.; Williamson, J.R. Transient Protein-RNA Interactions Guide Nascent Ribosomal RNA Folding. Cell, 2019, 179, 1357–1369.e16. doi: 10.1016/j.cell.2019.10.035
  27. Hu, Y.; Domínguez, C.M.; Bauer, J.; Weigel, S.; Schipperges, A.; Oelschlaeger, C.; Willenbacher, N.; Keppler, S.; Bastmeyer, M.; Heißler, S.; Wöll, C.; Scharnweber, T.; Rabe, K.S.; Niemeyer, C.M. Carbon-nanotube reinforcement of DNA-silica nanocomposites yields programmable and cell-instructive biocoatings. Nature Communications, 2019, 10, 5522. doi: 10.1038/s41467-019-13381-1
  28. Yeung, T.; Fung, O.; Bashkurov, M.; Khandani, A.; Subedar, O.; Wudwud, A.; Shaw, P.; Clarke, B.; Bartlett, J.; Rottapel, R.; Kapus, A. Avoidance of apoptotic death via a hyperploid salvage survival pathway after platinum treatment in high grade serous carcinoma cell line models. Oncotarget, 2019, 10, 6691–6712. doi: 10.18632/oncotarget.27330
  29. Zivanovic, J.; Kouroussis, E.; Kohl, J.B.; Adhikari, B.; Bursac, B.; Schott-Roux, S.; Petrovic, D.; Miljkovic, J.L.; Thomas-Lopez, D.; Jung, Y.; Miler, M.; Mitchell, S.; Milosevic, V.; Gomes, J.E.; Benhar, M.; Gonzales-Zorn, B.; Ivanovic-Burmazovic, I.; Torregrossa, R:; Mitchell, J.R.; Whiteman, M.; Schwarz, G.; Snyder, S.H.; Paul, B.D.; Carroll, K.S.; Filipovic, M.R. Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration. Cell Metabolism, 2019, 30(6), 1152–1170.e13. doi: 10.1016/j.cmet.2019.10.007
  30. Maksimenko, O.; Malinovskaya, Y.; Shipulo, E.; Osipova, N.; Razzhivina, V.; Arantseva, D.; Yarovaya, O.; Mostovaya, U.; Khalansky, A.; Fedoseeva, V.; Alekseeva, A.; Vanchugova, L.; Gorshkova, M.; Kovalenko, E.; Balabanyan, V.; Melnikov, P.; Baklaushev, V.; Chekhonin, V.; Kreuter, J.; Gelperina, S. Doxorubicin-loaded PLGA nanoparticles for the chemotherapy of glioblastomas: Towards the pharmaceutical development. International Journal of Pharmaceutics, 2019, 572, 118733. doi: 10.1016/j.ijpharm.2019.118733
  31. Wu, X.; Zhou, J.; Wang, F.; Meng, X.; Chen, J.; Chang, T.-S.; Lee, M.; Li, G.; Li, X.; Appelman, H.D.; Kuick, R.; Wang, T.D. Detection of colonic neoplasia in vivo using near-infrared-labeled peptide targeting cMet. Scientific Reports, 2019, 9, 17917. doi: 10.1038/s41598-019-54385-7
  32. Dones, J.M.; Tanrikulu, I.C.; Chacko, J.V.; Schroeder, A.B.; Hoang, T.T.; Gibson, A.L.F.; Eliceiri, K.W.; Raines, R.T. Optimization of interstrand interactions enables burn detection with a collagen-mimetic peptide. Organic & Biomolecular Chemistry, 2019, 17(46), 9906–9912. doi: 10.1039/c9ob01839e
  33. Liu, J.; Lee, R.; Britton, B.M.; London, J.A.; Yang, K.; Hanne, J.; Lee, J.-B.; Fishel, R. MutL sliding clamps coordinate exonuclease-independent Escherichia coli mismatch repair. Nature Communications, 2019. doi: 10.1038/s41467-019-13191-5
  34. Kholodenko, I.V.; Kalinovsky, D.V.; Svirshchevskaya, E.V.; Doronin, I.I.; Konovalova, M.V.; Kibardin, A.V.; Shamanskaya, T.V.; Larin, S.S.; Deyev, S.M.; Kholodenko, R.V. Multimerization through Pegylation Improves Pharmacokinetic Properties of scFv Fragments of GD2-Specific Antibodies. Molecules, 2019, 24(21), 3835. doi: 10.3390/molecules24213835
  35. Schwenk, J.; Boudkkazi, S.; Kocylowski, M.K.; Brechet, A.; Zolles, G.; Bus, T.; Costa, K.; Kollewe, A.; Jordan, J.; Bank, J.; Bildl, W.; Sprengel, R.; Kulik, A.; Roeper, J.; Schulte, U.; Fakler, B. An ER Assembly Line of AMPA-Receptors Controls Excitatory Neurotransmission and Its Plasticity. Neuron, 2019, 104(4), 680–692.e9. doi: 10.1016/j.neuron.2019.08.033
  36. Doh, J.; Tobin, S.; Beatty, K. Generation of CoilR Probe Peptides for VIPER-labeling of Cellular Proteins. Bio-protocol, 2019, 9(21), e3412. doi: 10.21769/bioprotoc.3412
  37. Zhou, L.; Wu, Y.; Luo, Y.; Li, H.; Meng, X.; Liu, Cl; Xiang, J.; Zhang, P.; Gong, P.; Cai, L. Mitochondria-localized Self-reporting Small Molecule Decorated Theranostic Agents for Cancer-organelle Transporting and Imaging. ACS Applied Bio Materials, 2019, 2(11), 5164–5173. doi: 10.1021/acsabm.9b00811
  38. Chen, L.; Zeng, D.; Xu, N.; Li, C.; Zhang, W.; Zhu, X.; Gao, Y.; Chen, P.R.; Lin, J. Blood-Brain Barrier- and Blood-Brain Tumor Barrier-Penetrating Peptide-Derived Targeted Therapeutics for Glioma and Malignant Tumor Brain Metastases. ACS Applied Materials & Interfaces, 2019, 11(45), 41889–41897. doi: 10.1021/acsami.9b14046
  39. Nieto-Orellana, A.; Li, H.; Rosiere, R.; Wauthoz, N..; Williams, H.; Monteiro, C.J.; Bosquillon, C.; Childerhouse, N.; Keegan, G.; Coghlan, D.; Mantovani, G.; Stolnik, S. Targeted PEG-poly(glutamic acid) complexes for inhalation protein delivery to the lung. Journal of Controlled Release, 2019, 316, 250–262. doi: 10.1016/j.jconrel.2019.10.012
  40. Saqr, A.; Vakili, M.R.; Huang, Y.-H.; Lai, R.; Lavasanifar, A. Development of Traceable Rituximab-Modified PEO-Polyester Micelles by Postinsertion of PEG-phospholipids for Targeting of B-cell Lymphoma. ACS Omega, 2019, 4(20), 18867–18879. doi: 10.1021/acsomega.9b02910
  41. Zhang, N.; Shi, S.; Jia, T.Z.; Ziegler, A.; Yoo, B.; Yuan, X.; Li, W.; Zhang, S. A general LC-MS-based RNA sequencing method for direct analysis of multiple-base modifications in RNA mixtures. Nucleic Acids Research, 2019, 47(20), e125. doi: 10.1093/nar/gkz731
  42. Katsumata, K.; Ishihara, J.; Mansurov, A.; Ishihara, A.; Raczy, M.M.; Yuba, E.; Hubbell, J.A. Targeting inflammatory sites through collagen affinity enhances the therapeutic efficacy of anti-inflammatory antibodies. Science Advances, 2019, 5(11), eaay1971. doi: 10.1126/sciadv.aay1971
  43. Sayers, E.J.; Peel, S.E.; Schantz, A.; England, R.M.; Beano, M.; Bates, S.M.; Desai, A.S.; Puri, S.; Ashford, M.B.; Jones, A.T. Endocytic Profiling of Cancer Cell Models Reveals Critical Factors Influencing LNP-Mediated mRNA Delivery and Protein Expression. Molecular Therapy, 2019, 27(11), 1950–1962. doi: 10.1016/j.ymthe.2019.07.018
  44. Zheng, Q.; Fang, Y.; Zeng, L.; Li, X.; Chen, H.; Song, H.; Huang, J.; Shi, S. Cytocompatible cerium oxide-mediated antioxidative stress in inhibiting ocular inflammation-associated corneal neovascularization. Journal of Materials Chemistry B, 2019, 7(43), 6759–6769. doi: 10.1039/c9tb01066a
  45. Xu, C.; Yu, Y.; Sun, Y.; Kong, L.; Yang, C.; Hu, M.; Yang, T.; Zhang, J.; Hu, Q.; Zhang, Z. Transformable Nanoparticle-Enabled Synergistic Elicitation and Promotion of Immunogenic Cell Death for Triple-Negative Breast Cancer Immunotherapy. Advanced Functional Materials, 2019, 29(45), 1905213. doi: 10.1002/adfm.201905213
  46. Nozeret, K.; Boucharlat, A.; Agou, F.; Buddelmeijer, N. A sensitive fluorescence-based assay to monitor enzymatic activity of the essential integral membrane protein Apolipoprotein N-acyltransferase (Lnt). Scientific Reports, 2019, 9, 15978. doi: 10.1038/s41598-019-52106-8
  47. Zhong, X.; Shtukenberg, A.G.; Liu, M.; Olson, I.A.; Weck, M.; Ward, M.D.; Kahr, B. Dislocation Generation by Microparticle Inclusions. Crystal Growth & Design, 2019, 19(11), 6649–6655. doi: 10.1021/acs.cgd.9b01041
  48. Phung, C.D.; Nguyen, H.T.; Choi, J.Y.; Pham, T.T.; Acharya, S.; Timilshina, M.; Chang, J.-H.; Kim, J.-H.; Jeong, J.H.; Ku, S.K.; Choi, H.-G.; Yong, C.S.; Kim, J.O. Reprogramming the T cell Response to Cancer by Simultaneous, Nanoparticle-mediated PD-L1 Inhibition and Immunogenic Cell Death. Journal of Controlled Release, 2019, 315, 126–138. doi: 10.1016/j.jconrel.2019.10.047
  49. Yang, Z.; Joyner, A.L. YAP1 is involved in replenishment of granule cell precursors following injury to the neonatal cerebellum. Developmental Biology, 2019, 455(2), 458–472. doi: 10.1016/j.ydbio.2019.07.018
  50. Zettlitz, K.A.; Waldmann, C.M.; Tsai, W.-T.K.; Tavaré, R.; Collins, J.; Murphy, J.M.; Wu, A.M. A Dual-Modality Linker Enables Site-Specific Conjugation of Antibody Fragments for 18F-Immuno-PET and Fluorescence Imaging. Journal of Nuclear Medicine, 2019, 60(10), 1467–1473. doi: 10.2967/jnumed.118.223560
  51. Morimoto, K.; Cole, K.S.; Kourelis, J.; Witt, C.H.; Brown, D.; Krahn, D.; Stegmann, M.; Kaschani, F.; Kaiser, M.; Burton, J.; Mohammed, S.; Yamaguchi-Shinozaki, K.; Weerapana, E.; van der Hoorn, R.A.L. Triazine Probes Target Ascorbate Peroxidases in Plants. Plant Physiology, 2019, 180(4), 1848–1859. doi: 10.1104/pp.19.00481
  52. Sarker, B.; Bagchi, A.; Walter, C.; Almeida, J.; Pathak, A. Longer collagen fibers trigger multicellular streaming on soft substrates via enhanced forces and cell-cell cooperation. Journal of Cell Science, 2019, 132(18), jcs226753. doi: 10.1242/jcs.226753
  53. Zhu, J.; Li, Z.; Zhang, C.; Lin, L.; Cao, S.; Che, H.; Shi, X.; Wang, H.; van Hest, J.C.M. Single enzyme loaded nanoparticles for combinational ultrasound-guided focused ultrasound ablation and hypoxia-relieved chemotherapy. Theranostics, 2019, 9(26), 8048–8060. doi: 10.7150/thno.37054
  54. Mazur, C.; Powers, B.; Zasadny, K.; Sullivan, J.M.; Dimant, H.; Kamme, F.; Hesterman, J.; Matson, J.; Oestergaard, M.; Seaman, M.; Holt, R.W.; Qutaish, M.; Polyak, I.; Coelho, R.; Gottumukkala, V.; Gaut, C.M.; Berridge, M.; Albargothy, N.J.; Kelly, L.; Carare, R.O.; Hoppin, J.; Kordasiewicz, H.; Swayze, E.E.; Verma, A. Brain pharmacology of intrathecal antisense oligonucleotides revealed through multimodal imaging. JCI Insight, 2019, 4(20), 129240. doi: 10.1172/jci.insight.129240
  55. Park, J.; Zhang, Y.; Saito, E.; Gurczynski, S.J.; Moore, B.B.; Cummings, B.J.; Anderson, A.J.; Shea, L.D. Intravascular innate immune cells reprogrammed via intravenous nanoparticles to promote functional recovery after spinal cord injury. Proceedings of the National Academy of Sciences of the U.S.A., 2019, 116(30), 14947–14954. doi: 10.1073/pnas.1820276116
  56. Poreba, M.; Groborz, K.; Vizovisek, M.; Maruggi, M.; Turk, D.; Turk, B.; Powis, G.; Drag, M.; Salvesen, G.S. Fluorescent probes towards selective cathepsin B detection and visualization in cancer cells and patient samples. Chemical Science, 2019, 10(36), 8461–8477. doi: 10.1039/c9sc00997c
  57. Simpson, J.D.; Ediriweera, G.R.; Howard, C.B.; Fletcher, N.L.; Bell, C.A.; Thurecht, K.J. Polymer design and component selection contribute to uptake, distribution & trafficking behaviours of polyethylene glycol hyperbranched polymers in live MDA-MB-468 breast cancer cells. Biomaterials Science, 2019, 7(11), 4661–4674. doi: 10.1039/c9bm00957d
  58. Tran, K.T.; Pallesen, J.S.; Solbak, S.M.Ø.; Narayanan, D.; Baig, A.; Zang, J.; Aguayo-Orozco, A.; Carmona, R.M.C.; Garcia, A.D.; Bach, A. A Comparative Assessment Study of Known Small-Molecule Keap1-Nrf2 Protein-Protein Interaction Inhibitors: Chemical Synthesis, Binding Properties, and Cellular Activity. Journal of Medicinal Chemistry, 2019, 62(17), 8028–8052. doi: 10.1021/acs.jmedchem.9b00723
  59. Luo, M.; Lewik, G.; Ratcliffe, J.C.; Choi, C.H.J.; Mäkilä, E.; Tong, W.Y.; Voelcker, N.H. Systematic Evaluation of Transferrin-Modified Porous Silicon Nanoparticles for Targeted Delivery of Doxorubicin to Glioblastoma. ACS Applied Materials & Interfaces, 2019, 11(37), 33637–33649. doi: 10.1021/acsami.9b10787
  60. Wang, J.; Johnson, A.G.; Lapointe, C.P.; Choi, J.; Prabhakar, A.; Chen, D.-H.; Petrov, A.N.; Puglisi, J.D. eIF5B gates the transition from translation initiation to elongation. Nature, 2019, 573, 605–608. doi: 10.1038/s41586-019-1561-0
  61. Synakewicz, M.; Bauer, D.; Rief, M.; Itzhaki, L.S. Bioorthogonal protein-DNA conjugation methods for force spectroscopy. Scientific Reports, 2019, 9, 13820. doi: 10.1038/s41598-019-49843-1
  62. Broadwater, D.; Bates, M.; Jayaram, M.; Young, M.; He, J.; Raithel, A.L.; Hamann, T.W.; Zhang, W.; Borhan, B.; Lunt, R.R.; Lunt, S.Y. Modulating cellular cytotoxicity and phototoxicity of fluorescent organic salts through counterion pairing. Scientific Reports, 2019, 9, 15288. doi: 10.1038/s41598-019-51593-z
  63. Cundiff, M.D.; Hurley, C.M.; Wong, J.D.; Boscia, J.A.; Bashyal, A.; Rosenberg, J:; Reichard, E.L.; Nassif, N.D.; Brodbelt, J.S.; Kraut, D.A. Ubiquitin receptors are required for substrate-mediated activation of the proteasome's unfolding ability. Scientific Reports, 2019, 9, 14506. doi: 10.1038/s41598-019-50857-y
  64. Caza, F.; Granger Joly de Boissel, P.; Villemur, R.; Betoulle, S.; St-Pierre, Y. Liquid biopsies for omics-based analysis in sentinel mussels. PLoS One, 2019, 14(10), e0223525. doi: 10.1371/journal.pone.0223525
  65. Pinder, C.; Matsuo, Y.; Maurer, S.P.; Toda, T. Kinesin-8 and Dis1/TOG collaborate to limit spindle elongation from prophase to anaphase A for proper chromosome segregation in fission yeast. Journal of Cell Science, 2019, 132(18), jcs232306. doi: 10.1242/jcs.232306
  66. Liu, X.; Ghosh, D. Intracellular nanoparticle delivery by oncogenic KRAS-mediated macropinocytosis. International Journal of Nanomedicine, 2019, 14, 6589–6600. doi: 10.2147/IJN.S212861
  67. Chen, X.; Wang, M.; Yang, X.; Wang, Y.; Yu, L.; Sun, J.; Ding, J. Injectable hydrogels for the sustained delivery of a HER2-targeted antibody for preventing local relapse of HER2+ breast cancer after breast-conserving surgery. Theranostics, 2019, 9(21), 6080–6098. doi: 10.7150/thno.36514
  68. Cun, X.; Chen, J.; Li, M.; He, X.; Tang, X.; Guo, R.; Deng, M.; Li, M.; Zhang, Z.; He, Q. Tumor-Associated Fibroblast-Targeted Regulation and Deep Tumor Delivery of Chemotherapeutic Drugs with a Multifunctional Size-Switchable Nanoparticle. ACS Applied Materials & Interfaces, 2019, 11(43), 39545–39559. doi: 10.1021/acsami.9b13957
  69. Wang, R.; Yao, X.; Li, T.; Li, X.; Jin, M.; Ni, Y.; Yuan, W.; Xie, X.; Lu, L.; Li, M. Reversible Thermoresponsive Hydrogel Fabricated from Natural Biopolymer for the Improvement of Critical Limb Ischemia by Controlling Release of Stem Cells. Advanced Healthcare Materials, 2019, 8(20), 1900967. doi: 10.1002/adhm.201900967
  70. Yen, T.-Y.; Stephen, Z.R.; Lin, G.; Mu, Q.; Jeon, M.; Untoro, S.; Welsh, P.; Zhang, M. Catalase-Functionalized Iron Oxide Nanoparticles Reverse Hypoxia-Induced Chemotherapeutic Resistance. Advanced Healthcare Materials, 2019, 8(20), 1900826. doi: 10.1002/adhm.201900826
  71. Wang, J.; Wang, Z.; Yu, J.; Zhang, Y.; Zeng, Y.; Gu, Z. A forskolin-conjugated insulin analog targeting endogenous glucose-transporter for glucose-responsive insulin delivery. Biomaterials Science, 2019, 7(11), 4508–4513. doi: 10.1039/c9bm01283d
  72. Chin, D.D.; Wang, J.; Mel de Fontenay, M.; Plotkin, A.; Magee, G.A.; Chung, E.J. Hydroxyapatite-binding micelles for the detection of vascular calcification in atherosclerosis. Journal of Materials Chemistry B, 2019, 7(41), 6449–6457. doi: 10.1039/c9tb01918a
  73. Hampoelz, B.; Schwarz, A.; Ronchi, P.; Bragulat-Teixidor, H.; Tischer, C.; Gaspar, I.; Ephrussi, A.; Schwab, Y.; Beck, M. Nuclear Pores Assemble from Nucleoporin Condensates During Oogenesis. Cell, 2019, 179, 671–686.e17. doi: 10.1016/j.cell.2019.09.022
  74. Rho, J.Y.; Cox, H.; Mansfield, E.D.H.; Ellacott, S.H.; Peltier, R.; Brendel, J.C.; Hartlieb, M.; Waigh, T.A.; Perrier, S. Dual self-assembly of supramolecular peptide nanotubes to provide stabilisation in water. Nature Communications, 2019, 10, 4708. doi: 10.1038/s41467-019-12586-8
  75. Li, L.; Wang, J.; Li, Y.; Radford, D.C.; Yang, J.; Kopeček, J. Broadening and Enhancing Functions of Antibodies by Self-Assembling Multimerization at Cell Surface. ACS Nano, 2019, 13(10), 11422–11432. doi: 10.1021/acsnano.9b04868
  76. Che, L.; Liu, Z.; Wang, D.; Xu, C.; Zhang, C.; Meng, J.; Zheng, J.; Yuan, H.; Zhao, G.; Zhou, X. Computer-assisted Engineering of Programmed Drug Releasing Multilayer Nanomedicine via Indomethacin-mediated Ternary Complex for Therapy Against a Multidrug Resistant Tumor. Acta Biomaterialia, 2019, 97, 461–473. doi: 10.1016/j.actbio.2019.07.033
  77. Khatri, S.; Hansen, J.; Mendes, A.C.; Chronakis, I.S.; Hung, S.-C.; Mellins, E.D.; Astakhova, K. Citrullinated Peptide Epitope Targets Therapeutic Nanoparticles to Human Neutrophils. Bioconjugate Chemistry, 2019, 30(10), 2584–2593. doi: 10.1021/acs.bioconjchem.9b00518
  78. Zhu, X.; Nguyen, B.; You, J.B.; Karakolis, E.; Sinton, D.; Rochman, C. Identification of Microfibers in the Environment Using Multiple Lines of Evidence. Environmental Science and Technology, 2019, 53(20), 11877–11887. doi: 10.1021/acs.est.9b05262
  79. Akl, M.A.; Kartal-Hodzic, A.; Suutari, T.; Oksanen, T.; Montagner, I.M.; Rosato, A.; Ismael, H.R.; Afouna, M.I.; Caliceti, P.; Yliperttula, M.; Samy, A.M.; Mastrotto, F.; Salmaso, S.; Viitala, T. Real-Time Label-Free Targeting Assessment and in Vitro Characterization of Curcumin-Loaded Poly-lactic-co-glycolic Acid Nanoparticles for Oral Colon Targeting. ACS Omega, 2019, 4(16), 16878–16890. doi: 10.1021/acsomega.9b02086
  80. Zhou, X.; Ling, K.; Liu, M.; Zhang, X.; Ding, J.; Dong, Y.; Liang, Z.; Li, J.; Zhang, J. Targeted Delivery of Cisplatin-Derived Nanoprecursors via a Biomimetic Yeast Microcapsule for Tumor Therapy by the Oral Route. Theranostics, 2019, 9(22), 6568–6586. doi: 10.7150/thno.35353
  81. Retout, M.; Brunetti, E.; Valkenier, H.; Bruylants, G. Limits of thiol chemistry revealed by quantitative analysis of mixed layers of thiolated-PEG ligands grafted onto gold nanoparticles. Journal of Colloid and Interface Science, 2019, 557, 807–815. doi: 10.1016/j.jcis.2019.09.047
  82. Harris, J.M.; Bentley, M.D.; Moreadith, R.W.; Viegas, T.X.; Fang, Z.; Yoon, K.; Weimer, R.; Dizman, B.; Nordstierna, L. Tuning Drug Release From Polyoxazoline-Drug Conjugates. European Polymer Journal, 2019, 120, 109241. doi: 10.1016/j.eurpolymj.2019.109241
  83. Gapizov, S.Sh.; Petrovskaya, L.E.; Shingarova, L.N.; Kryukova, E.A.; Boldyreva, E.F.; Lukashev, E.P.; Yakimov, S.A.; Svirshchevskaya, E.V.; Dolgikh, D.A.; Kirpichnikov, M.P. Fusion with an albumin-binding domain improves pharmacokinetics of an αvβ3-integrin binding fibronectin scaffold protein. Biotechnology and Applied Biochemistry, 2019, 66(4), 617–625. doi: 10.1002/bab.1762
  84. Antonov, S.A.; Novosadova, E.V.; Kobylansky, A.G.; Tarantul, V.Z.; Grivennikov, I.A. A Hybrid Detection Method Based on Peroxidase-mediated Signal Amplification and Click Chemistry for Highly Sensitive Background-free Immunofluorescent Staining. Journal of Histochemistry & Cytochemistry, 2019, 67(10), 771–782. doi: 10.1369/0022155419864113
  85. Kesarwani, V.; Kelly, H.G.; Shankar, M.; Robinson, K.J.; Kent, S.J.; Traven, A.; Corrie, S.R. Characterisation of key bio-nano interactions between organosilica nanoparticles and Candida albicans. ACS Applied Materials & Interfaces, 2019, 11(38), 34676–34687. doi: 10.1021/acsami.9b10853
  86. Wang, Y.; Yuan, Q.; Feng, W.; Pu, W.; Ding, J.; Zhang, H.; Li, X.; Yang, B.; Dai, Q.; Cheng, L.; Wang, J.; Sun, F.; Zhang, D. Targeted delivery of antibiotics to the infected pulmonary tissues using ROS-responsive nanoparticles. Journal of Nanobiotechnology, 2019, 17, 103. doi: 10.1186/s12951-019-0537-4
  87. Bretin, L.; Pinon, A.; Bouramtane, S.; Ouk, C.; Richard, L.; Perrin, M.-L.; Chaunavel, A.; Carrion, C.; Bregier, F.; Sol, V.; Chaleix, V.; Leger, D.Y.; Liagre, B. Photodynamic Therapy Activity of New Porphyrin-Xylan-Coated Silica Nanoparticles in Human Colorectal Cancer. Cancers, 2019, 11(10), 1474. doi: 10.3390/cancers11101474
  88. Zhang, C.; Ling, X.; Guo, Y.; Yuan, C.; Cheng, H.; Ye, X.; Ma, R.; Zhang, Y.; Li, Y.; Chang, X.; Kong, B.; Liu, T.; Cui, H. Evaluation of COC183B2 antibody targeting ovarian cancer by near-infrared fluorescence imaging. Chinese Journal of Cancer Research, 2019, 31, 673–685. doi: 10.21147/j.issn.1000-9604.2019.04.11
  89. Ou, W.; Jiang, L.; Gu, Y.; Soe, Z.C.; Kim, B.K.; Gautam, M.; Poudel, K.; Pham, L.M.; Phung, C.D.; Chang, J.-H.; Kim, J.R.; Ku, S.K.; Yong, C.S.; Kim, J.O. Regulatory T Cells Tailored with pH-Responsive Liposomes Shape an Immuno-Antitumor Milieu against Tumors. ACS Applied Materials & Interfaces, 2019, 11(40), 36333–36346. doi: 10.1021/acsami.9b11371
  90. Gardinier, T.C.; Turker, M.Z.; Hinckley, J.A.; Katt, W.P.; DomNwachukwu, N.; Woodruff, F.; Hersh, J.; Wang, J.; Cerione, R.A.; Wiesner, U.B. Controlling Surface Chemical Heterogeneities of Ultrasmall Fluorescent Core–Shell Silica Nanoparticles as Revealed by High-Performance Liquid Chromatography. The Journal of Physical Chemistry C, 2019, 123(37), 23246–23254. doi: 10.1021/acs.jpcc.9b06905
  91. Lee, S.A.; Biteen, J.S. Spectral Reshaping of Single Dye Molecules Coupled to Single Plasmonic Nanoparticles. Journal of Physical Chemistry Letters, 2019, 10, 5764–5769. doi: 10.1021/acs.jpclett.9b02480
  92. Srinageshwar, B.; Dils, A.; Sturgis, J.; Wedster, A.; Kathirvelu, B.; Baiyasi, S.; Swanson, D.; Sharma, A.; Dunbar, G.L.; Rossignol, J. Surface-Modified G4 PAMAM Dendrimers Cross the Blood-Brain Barrier Following Multiple Tail-Vein Injections in C57BL/6J Mice. ACS Chemical Neuroscience, 2019, 10(9), 4145–4150. doi: 10.1021/acschemneuro.9b00347
  93. Ju, Y.; Guo, H.; Yarber, F.; Edman, M.C.; Peddi, S.; Janga, S.R.; MacKay, J.A.; Hamm-Alvarez, S.F. Molecular Targeting of Immunosuppressants Using a Bi-functional Elastin-Like Polypeptide. Bioconjugate Chemistry, 2019, 30(9), 2358–2372. doi: 10.1021/acs.bioconjchem.9b00462
  94. Alshanski, I.; Blaszkiewicz, J.; Mervinetsky, E.; Rademann, J.; Yitzchaik, S.; Hurevich, M. Sulfation Patterns of Saccharides and Heavy Metal Ions Binding. Chemistry, 2019, 25(52), 12083–12090. doi: 10.1002/chem.201901538
  95. Hwang, D.; Nilchan, N.; Nanna, A.R.; Li, X.; Cameron, M.D.; Roush, W.R.; Park, H.; Rader, C. Site-Selective Antibody Functionalization via Orthogonally Reactive Arginine and Lysine Residues. Cell Chemical Biology, 2019, 26(9), 1229–1239. doi: 10.1016/j.chembiol.2019.05.010
  96. Jang, E.K.; Son, R.G.; Pack, S.P.;. Novel enzymatic single-nucleotide modification of DNA oligomer: prevention of incessant incorporation of nucleotidyl transferase by ribonucleotide-borate complex. Nucleic Acids Research, 2019, 47(17), e102. doi: 10.1093/nar/gkz612
  97. Zhang, T.; Lip, H.; He, C.; Cai, P.; Wang, Z.; Henderson, J.T.; Rauth, A.M.; Wu, X.Y. Multitargeted Nanoparticles Deliver Synergistic Drugs across the Blood-Brain Barrier to Brain Metastases of Triple Negative Breast Cancer Cells and Tumor-Associated Macrophages. Advanced Healthcare Materials, 2019, 8(18), 1900543. doi: 10.1002/adhm.201900543
  98. Chen, T.; He, B.; Tao, J.; He, Y.; Deng, H.; Wang, X.; Zheng, Y. Application of Förster Resonance Energy Transfer (FRET) technique to elucidate intracellular and in vivo biofate of nanomedicines. Advanced Drug Delivery Reviews, 2019, 143, 177–205. doi: 10.1016/j.addr.2019.04.009
  99. Sundah, N.R.; Ho, N.R.Y.; Lim, G.S.; Natalia, A.; Ding, X.; Liu, Y.; Seet, J.E.; Chan, C.W.; Loh, T.P.; Shao, H. Barcoded DNA nanostructures for the multiplexed profiling of subcellular protein distribution. Nature Biomedical Engineering, 2019, 3(9), 684–694. doi: 10.1038/s41551-019-0417-0
  100. Lee, S.H.; Park, O.K.; Kim, J.; Shin, K.; Pack, C.G.; Kim, K.; Ko, G.; Lee, N.; Kwon, S.-H.; Hyeon, T. Deep tumor penetration of drug-loaded nanoparticles by click reaction-assisted immune cell targeting strategy. Journal of the American Chemical Society, 2019, 141(35), 13829–13840. doi: 10.1021/jacs.9b04621
  101. Saito, E.; Kuo, R.; Kramer, K.R.; Gohel, N.; Giles, D.A.; Moore, B.B.; Miller, S.D.; Shea, L.D. Design of biodegradable nanoparticles to modulate phenotypes of antigen presenting cells for antigen-specific treatment of autoimmune disease. Biomaterials, 2019, 222, 119432. doi: 10.1016/j.biomaterials.2019.119432
  102. Binkley, M.M.; Cui, M.; Li, W.; Tan, S.; Berezin, M.Y.; Meacham, J.M. Design, modeling, and experimental validation of an acoustofluidic platform for nanoscale molecular synthesis and detection. Physics of Fluids, 2019, 31, 082007. doi: 10.1063/1.5100149
  103. Jandl, B.; Sedghiniya, S.; Carstens, A.; Astakhova, K. Peptide–Fluorophore Hydrogel as a Signal Boosting Approach in Rapid Detection of Cancer DNA. ACS Omega, 2019, 4(9), 13889–13895. doi: 10.1021/acsomega.9b01586
  104. Ruiz, A.; Bravo, D.; Duarte, A.; Adler, R.S.; Raya, J.G. Accuracy of Ultrasound-Guided versus Landmark-Guided Intra-articular Injection for Rat Knee Joints. Ultrasound in Medicine and Biology, 2019, 45(10), 2787–2796. doi: 10.1016/j.ultrasmedbio.2019.06.403
  105. Mahmoud, A.; de Jongh, P.; Briere, S.; Chen, M.Z.; Nowell, C.J.; Johnston, A.P.R.; Davis, T.P.; Haddleton, D.M.; Kempe, K. Carboxylated Cy5-labeled Comb Polymers Passively Diffuse the Cell Membrane and Target Mitochondria. ACS Applied Materials & Interfaces, 2019, 11(34), 31302–31310. doi: 10.1021/acsami.9b09395
  106. Kim, H.J.; Yen, L.; Wongpalee, S.P.; Kirshner, J.A.; Mehta, N.; Xue, Y.; Johnston, J.B.; Burlingame, A.L.; Kim, J.K.; Loparo, J.J.; Jacobsen, S.E. The Gene-Silencing Protein MORC-1 Topologically Entraps DNA and Forms Multimeric Assemblies to Cause DNA Compaction. Molecular Cell, 2019, 75, 700–710. doi: 10.1016/j.molcel.2019.07.032
  107. Sergeant, K.; Printz, B.; Guerriero, G.; Renaut, J.; Lutts, S.; Hausman, J.-F. The Dynamics of the Cell Wall Proteome of Developing Alfalfa Stems. Biology, 2019, 8(3), 60. doi: 10.3390/biology8030060
  108. Lomakin, Y.A.; Kudryaeva, A.A.; Kostin, N.N.; Terekhov, S.S.; Kaminskaya, A.N.; Zakharova, M.N.; Ivanova, M.V.; Simaniv, T.O.; Gabibov, A.G.; Belogurov, A.A. Differential Diagnostics of Active Progressing Multiple Sclerosis Using a Fluorescent Biomarker with Resonance Energy Transfer. Bulletin of Experimental Biology and Medicine, 2019, 167(3), 329–334. doi: 10.1007/s10517-019-04520-1
  109. Bruniaux, J.; Allard-Vannier, E.; Aubrey, N.; Lakhrif, Z.; Ben Djemaa, S.; Eljack, S.; Marchais, H.; Hervé-Aubert, K.; Chourpa, I.; David, S. Magnetic nanocarriers for the specific delivery of siRNA: contribution of breast cancer cells active targeting for down-regulation efficiency. International Journal of Pharmaceutics, 2019, 569, 118572. doi: 10.1016/j.ijpharm.2019.118572
  110. Zhuang, Y.; Yang, X.; Li, Y.; Chen, Y.; Peng, X.; Yu, L.; Ding, J. Sustained Release Strategy Designed for Lixisenatide Delivery to Synchronously Treat Diabetes and Associated Complications. ACS Applied Materials & Interfaces, 2019, 11(33), 29604–29618. doi: 10.1021/acsami.9b10346
  111. Kretzmann, J.A.; Evans, C.W.; Moses, C.; Sorolla, A.; Kretzmann, A.L.; Wang, E.; Ho, D.; Hackett, M.J.; Dessauvagie, B.F.; Smith, N.M.; Redfern, A.D.; Waryah, C.; Norret, M.; Iyer, K.S.; Blancafort, P. Tumour suppression by targeted intravenous non-viral CRISPRa using dendritic polymers. Chemical Science, 2019, 10(33), 7718–7727. doi: 10.1039/c9sc01432b
  112. Turker, M.Z.; Gardinier, T.C.; Hinckley, J.A.; Contreras, C.B.; Woodruff, F.; Ma, K.; Kohle, F.F.E.; Wiesner, U.B. Inner and Outer Surface Functionalizations of Ultrasmall Fluorescent Silica Nanorings As Shown by High-Performance Liquid Chromatography. Chemistry of Materials, 2019, 31(15), 5519–5528. doi: 10.1021/acs.chemmater.9b01236
  113. Sharma, P.; Mesci, P.; Carromeu, C.; McClatchy, D.R.; Schiapparelli, L.; Yates, J.R.; Muotri, A.R.; Cline, H.T. Exosomes regulate neurogenesis and circuit assembly. Proceedings of the National Academy of Sciences of the U.S.A., 2019, 116(32), 16086–16094. doi: 10.1073/pnas.1902513116
  114. Pearce, H.A.; Qian, H.; Connell, T.U.; Huang, D.; Gottstein, C.; Donnelly, P.S.; Peter, K.; Gregorevic, P.; Hagemeyer, C.E. Site-specific glycation and chemo-enzymatic antibody sortagging for the retargeting of rAAV6 to inflamed endothelium. Molecular Therapy - Methods & Clinical Development, 2019, 14, 261–269. doi: 10.1016/j.omtm.2019.07.003
  115. Gaikwad, H.; Wang, G.; Smith, W.J.; Alexander, K.L.; D'Alessandro, A.; Zhang, W.; Purev, E.; Simberg, D. Clickable Methyltetrazine-Indocarbocyanine Lipids: A Multicolor Tool Kit for Efficient Modifications of Cell Membranes. Bioconjugate Chemistry, 2019, 30(8), 2106–2114. doi: 10.1021/acs.bioconjchem.9b00202
  116. Melo, M.; Nunes, R.; Sarmento, B.; das Neves, J. Colorectal distribution and retention of polymeric nanoparticles following incorporation into a thermosensitive enema. Biomaterials Science, 2019, 7(9), 3801–3811. doi: 10.1039/c9bm00759h
  117. Bykov, Y.; Cohen, N.; Gabrielli, N.; Manenschijn, H.; Welsch, S.; Chlanda, P.; Kukulski, W.; Patil, K.R.R.; Schuldiner, M.; Briggs, J.A.G. High-throughput ultrastructure screening using electron microscopy and fluorescent barcoding. Journal of Cell Biology, 2019, 218(8), 2797–2811. doi: 10.1083/jcb.201812081
  118. Malfanti, A.; Scomparin, A.; Pozzi, S.; Gibori, H.; Krivitsky, A.; Satchi-Fainaro, R.; Mastrotto, F.; Caliceti, P.; Salmaso, S. Oligo-guanidyl targeted bioconjugates forming rod shaped polyplexes as a new nanoplatform for oligonucleotide delivery. Journal of Controlled Release, 2019, 310, 58–73. doi: 10.1016/j.jconrel.2019.08.005
  119. Kim, K.-S.; Han, J.-H.; Park, J.-H.; Kim, H.-K.; Choi, S.H.; Kim, G.R.; Song, H.; An, H.J.; Han, D.K.; Park, W.; Park, K.-S. Multifunctional nanoparticles for genetic engineering and bioimaging of natural killer (NK) cell therapeutics. Biomaterials, 2019, 221, 119418. doi: 10.1016/j.biomaterials.2019.119418
  120. Rancan, F.; Volkmann, H.; Giulbudagian, M.; Schumacher, F.; Stanko, J.I.; Kleuser, B.; Blume-Peytavi, U.; Calderón, M.; Vogt, A. Dermal Delivery of the High-Molecular-Weight Drug Tacrolimus by Means of Polyglycerol-Based Nanogels. Pharmaceutics, 2019, 11(8), E394. doi: 10.3390/pharmaceutics11080394
  121. Kater, L.; Frieg, B.; Berninghausen, O.; Gohlke, H.; Beckmann, R.; Kedrov, A. Partially inserted nascent chain unzips the lateral gate of the Sec translocon. EMBO Reports, 2019, e48191. doi: 10.15252/embr.201948191
  122. Kosmider, B.; Lin, C.-R.; Karim, L.; Tomar, D.; Vlasenko, L.; Marchetti, N.; Bolla, S.; Madesh, M.; Criner, G.J.; Bahmed, K. Mitochondrial dysfunction in human primary alveolar type II cells in emphysema. EBioMedicine, 2019, 46, 305–316. doi: 10.1016/j.ebiom.2019.07.063
  123. Graber-Feesl, C.L.; Pederson, K.D.; Aney, K.J.; Shima, N. Mitotic DNA Synthesis Is Differentially Regulated between Cancer and Noncancerous Cells. Molecular Cancer Research, 2019, 17(8), 1687–1698. doi: 10.1158/1541-7786.MCR-19-0057
  124. Skubalova, Z.; Michalkova, H.; Michalek, P.; Strmiska, V.; Guran, R.; Rodrigo, M.A.M.; Castkova, K.; Hynek, D.; Pekarik, V.; Zitka, O.; Adam, V.; Heger, Z. Prevalent Anatase Crystalline Phase Increases the Cytotoxicity of Biphasic Titanium Dioxide Nanoparticles in Mammalian Cells. Colloids and Surfaces, B: Biointerfaces, 2019, 182, 110391. doi: 10.1016/j.colsurfb.2019.110391
  125. Brady, S.; Singh, G.; Bolinger, C.; Song, Z.; Boeras, I.; Weng, K.; Trent, B.; Brown, W.C.; Singh, K.; Boris-Lawrie, K.; Heng, X. Virion-associated, host-derived DHX9/RNA helicase A enhances the processivity of HIV-1 reverse transcriptase on genomic RNA. Journal of Biological Chemistry, 2019, 294(30), 11473–11485. doi: 10.1074/jbc.RA119.007679
  126. São Pedro, M.N.; Azevedo, A.M.; Aires-Barros, M.R.; Soares, R.R.G. Minimizing the influence of fluorescent tags on IgG partition in PEG-salt aqueous two-phase systems for rapid screening applications. Biotechnology Journal, 2019, 14(8), 1800640. doi: 10.1002/biot.201800640
  127. Yim, M.S.; Son, E.J.; Kim, H.N.; Ryu, E.K. A TAT-conjugated peptide inhibitor of polo-like kinase 1 for in vivo tumor imaging. Journal of Analytical Science and Technology, 2019, 10(1), 26. doi: 10.1186/s40543-019-0187-z
  128. Yang, F.; Teoh, F.; Tan, A.S.M.; Cao, Y.; Pavelka, N.; Berman, J. Aneuploidy enables cross-adaptation to unrelated drugs. Molecular Biology and Evolution, 2019, 36(8), 1768–1782. doi: 10.1093/molbev/msz104
  129. Jensen, D.; Manzano, A.R.; Rammohan, J.; Stallings, C.L.; Galburt, E.A. CarD and RbpA modify the kinetics of initial transcription and slow promoter escape of the Mycobacterium tuberculosis RNA polymerase. Nucleic Acids Research, 2019, 47(13), 6685–6698. doi: 10.1093/nar/gkz449
  130. Li, Z.; Lin, J.; Sulchek, T.; Cruz, M.A.; Wu, J.; Dong, J.-F.; Zhu, C. Domain specific mechanical modulation of VWF-ADAMTS13 interaction. Molecular Biology of the Cell, 2019, 30(16), 1920–1929. doi: 10.1091/mbc.E19-01-0021
  131. Gao, F.; Hunter, A.; Qu, S.; Hoffman, J.R.; Gao, P.; Phillip, W.A. Interfacial Junctions Control Electrolyte Transport Through Charge-Patterned Membranes. ACS Nano, 2019, 13(7), 7655–7664. doi: 10.1021/acsnano.9b00780
  132. Chen, Y.; Zhao, G.; Wang, S.; He, Y.; Han, S.; Du, C.; Li, S.; Fan, Z.; Wang, C.; Wang, J. Platelet-membrane-camouflaged bismuth sulfide nanorods for synergistic radio-photothermal therapy against cancer. Biomaterials Science, 2019, 7(8), 3450–3459. doi: 10.1039/c9bm00599d
  133. Huang, H.; Zhou, M.; Ruan, L.; Wang, D.; Lu, H.; Zhang, J.; Chen, J.; Hu, Y.; Chai, Z. AMPK mediates the neurotoxicity of iron oxide nanoparticles retained in mitochondria or lysosomes. Metallomics, 2019, 11(7), 1200–1206. doi: 10.1039/c9mt00103d
  134. Chen, C.; Corry, B.; Huang, L.; Hildebrandt, N. FRET-modulated multi-hybrid nanoparticles for brightness-equalized single-wavelength barcoding. Journal of the American Chemical Society, 2019, 141(28), 11123–11141. doi: 10.1021/jacs.9b03383
  135. Nguyen, H.T.; Byeon, J.H.; Phung, C.D.; Pham, L.M.; Ku, S.K.; Yong, C.S.; Kim, J.O. Method for the Instant In-Flight Manufacture of Black Phosphorus to Assemble Core@Shell Nanocomposites for Targeted Photoimmunotherapy. ACS Applied Materials & Interfaces, 2019, 11(28), 24959–24970. doi: 10.1021/acsami.9b04632
  136. Roloff, A.; Nirmalananthan-Budau, N.; Rühle, B.; Borcherding, H.; Thiele, T.; Schedler, U.; Resch-Genger, U. Quantification of Aldehydes on Polymeric Microbead Surfaces via Catch and Release of Reporter Chromophores. Analytical Chemistry, 2019, 91(14), 8827–8834. doi: 10.1021/acs.analchem.8b05515
  137. Al-Lawati, H.; Vakili, M.R.; Lavasanifar, A.; Ahmed, S.; Jamali, F. Delivery and biodistribution of traceable polymeric micellar diclofenac in the rat. Journal of Pharmaceutical Sciences, 2019, 108(8), 2698–2707. doi: 10.1016/j.xphs.2019.03.016
  138. Huang, S.; Qi, J.; deQuilettes, D.W.; Huang, M.; Lin, C.-W.; Bardhan, N.M.; Dang, X.; Bulović, V.; Belcher, A.M. M13 Virus-Based Framework for High Fluorescence Enhancement. Small, 2019, 15(28), 1901233. doi: 10.1002/smll.201901233
  139. Son, K.; You, J.-S.; Yoon, M.-S.; Dai, C.; Kim, J.H.; Khanna, N.; Banerjee, A.; Martinis, S.A.; Han, G.; Han, J.M.; Kim, S.; Chen, J. Nontranslational function of leucyl-tRNA synthetase regulates myogenic differentiation and skeletal muscle regeneration. Journal of Clinical Investigation, 2019, 130, 2088–2093. doi: 10.1172/JCI122560
  140. Zhang, Y.; Pan, J.; Li, H.; Yu, D.; Wu, T.; Wang, L.; Wang, Y.; Zhou, L.; Zheng, S. Albumin Based Nanomedicine for Enhancing Tacrolimus Safety and Lymphatic Targeting Efficiency. Journal of Biomedical Nanotechnology, 2019, 15(6), 1313–1324. doi: 10.1166/jbn.2019.2777
  141. Pantelidou, C.; Sonzogni, O.; De Oliveria Taveira, M.; Mehta, A.K.; Kothari, A.; Wang, D.; Visal, T.; Li, M.K.; Pinto, J.; Castrillon, J.A.; Cheney, E.M.; Bouwman, P.; Jonkers, J.; Rottenberg, S.; Guerriero, J.L.; Wulf, G.M.; Shapiro, G.I. PARP Inhibitor Efficacy Depends on CD8+ T-cell Recruitment via Intratumoral STING Pathway Activation in BRCA-Deficient Models of Triple-Negative Breast Cancer. Cancer Discovery, 2019, 9(6), 722–737. doi: 10.1158/2159-8290.CD-18-1218
  142. Zbyszynski, P.; Toraason, I.; Repp, L.; Kwon, G.S. Probing the subcutaneous absorption of a PEGylated FUD peptide nanomedicine via in vivo fluorescence imaging. Nano Convergence, 2019, 6(1), 22. doi: 10.1186/s40580-019-0192-3
  143. Catipovic, M.A.; Bauer, B.W.; Loparo, J.J.; Rapoport, T.A. Protein translocation by the SecA ATPase occurs by a power-stroke mechanism. EMBO Journal, 2019, 38(9), e101140. doi: 10.15252/embj.2018101140
  144. DuRoss, A.N.; Neufeld, M.J.; Landry, M.R.; Rosch, J.G.; Eaton, C.T.; Sahay, G.; Thomas, C.R.; Sun, C. Micellar Formulation of Talazoparib and Buparlisib for Enhanced DNA Damage in Breast Cancer Chemoradiotherapy. ACS Applied Materials & Interfaces, 2019, 11(13), 12342–12356. doi: 10.1021/acsami.9b02408
  145. Truebenbach, I.; Kern, S.; Loy, D.M.; Höhn, M.; Gorges, J.; Kazmaier, U.; Wagner, E. Combination Chemotherapy of L1210 Tumors in Mice with Pretubulysin and Methotrexate Lipo-Oligomer Nanoparticles. Molecular Pharmaceutics, 2019, 16(6), 2405–2417. doi: 10.1021/acs.molpharmaceut.9b00038
  146. van der Meer, S.B.; Loza, K.; Wey, K.; Heggen, M.; Beuck, C.; Bayer, P.; Epple, M. . Click Chemistry on the Surface of Ultrasmall Gold Nanoparticles (2 nm) for Covalent Ligand Attachment Followed by NMR Spectroscopy, 2019, 35(22), 7191–7204. doi: 10.1021/acs.langmuir.9b00295
  147. Parayath, N.N.; Gandham, S.K.; Leslie, F.; Amiji, M.M. Improved Anti-TumorEfficacy of Paclitaxel in Combination with MicroRNA-125b-based Tumor-Associated Macrophage Repolarization in Epithelial Ovarian Cancer. Cancer Letters, 2019, 461, 1–9. doi: 10.1016/j.canlet.2019.07.002
  148. Novoselova, M.V.; Voronin, D.V.; Abakumova, T.O.; Demina, P.A.; Petrov, A.V.; Petrov, V.V.; Zatsepin, T.S.; Sukhorukov, G.B.; Gorin, D.A. Focused ultrasound-mediated fluorescence of composite microcapsules loaded with magnetite nanoparticles: In vitro and in vivo study. Colloids and Surfaces. B: Biointerfaces, 2019, 181, 680–687. doi: 10.1016/j.colsurfb.2019.06.025
  149. Conibear, A.C.; Thewes, K.; Groysbeck, N.; Becker, C.F.W. Multifunctional Scaffolds for Assembling Cancer-Targeting Immune Stimulators Using Chemoselective Ligations. Frontiers in Chemistry, 2019, 7, 113. doi: 10.3389/fchem.2019.00113
  150. Wang, Y.; Li, K.; Han, S.; Tian, Y.-H.; Hu, P.-C.; Xu, X.-L.; He, Y.-Q.; Pan, W.-T.; Gao, Y.; Zhang, Z.; Zhang, J.-W.; Wei, L. Chlorotoxin targets ERα/VASP signaling pathway to combat breast cancer. Cancer Medicine, 2019, 8(4), 1679–1693. doi: 10.1002/cam4.2019
  151. Shi, B.; Wu, M.; Li, Z.; Xie, Z.; Wei, X.; Fan, J.; Xu, Y.; Ding, D.; Akash, S.H.; Chen, S.; Cao, S. Antitumor activity of a 5T4 targeting antibody drug conjugate with a novel payload derived from MMAF via C-Lock linker. Cancer Medicine, 2019, 8(4), 1793–1805. doi: 10.1002/cam4.2066
  152. Yoneoka, S.; Nakagawa, Y.; Uto, K.; Sakura, K.; Tsukahara, T.; Ebara, M. Boron-incorporating hemagglutinating virus of Japan envelope (HVJ-E) nanomaterial in boron neutron capture therapy. Science and Technology of Advanced Materials, 2019, 20(1), 291–304. doi: 10.1080/14686996.2019.1586051
  153. Andersen, V.L.; Vinther, M.; Kumar, R.; Ries, A.; Wengel, J.; Nielsen, J.S.; Kjems, J. A self-assembled, modular nucleic acid-based nanoscaffold for multivalent theranostic medicine. Theranostics, 2019, 9(9), 2662–2677. doi: 10.7150/thno.32060
  154. Kukushkin, V.I.; Ivanov, N.M.; Novoseltseva, A.A.; Gambaryan, A.S.; Yaminsky, I.V.; Kopylov, A.M.; Zavyalova, E.G. Highly sensitive detection of influenza virus with SERS aptasensor. PLoS One, 2019, 14(4), e0216247. doi: 10.1371/journal.pone.0216247
  155. Kirkham, C.M.; Scott, J.N.F.; Wang, X.; Smith, A.L.; Kupinski, A.P.; Ford, A.M.; Westhead, D.R.; Stockley, P.G.; Tuma, R.; Boyes, J. Cut-and-Run: A Distinct Mechanism by which V(D)J Recombination Causes Genome Instability. Molecular Cell, 2019, 74(3), 584–597.e9. doi: 10.1016/j.molcel.2019.02.025
  156. Ha, S.-W.; Hwang, K.; Jin, J.; Cho, A.-S.; Kim, T.Y.; Hwang, S.I.; Lee, H.J.; Kim, C.-Y. Ultrasound-sensitizing nanoparticle complex for overcoming the blood-brain barrier: an effective drug delivery system. International Journal of Nanomedicine, 2019, 14, 3743–3752. doi: 10.2147/ijn.s193258
  157. Zhang, Q.; Zhang, F.; Li, S.; Liu, R.; Jin, T.; Dou, Y.; Zhou, Z.; Zhang, J. A Multifunctional Nanotherapy for Targeted Treatment of Colon Cancer by Simultaneously Regulating Tumor Microenvironment. Theranostics, 2019, 9(13), 3732–3753. doi: 10.7150/thno.34377
  158. Armache, J.P.; Gamarra, N.; Johnson, S.L.; Leonard, J.D.; Wu, S.; Narlikar, G.J.; Cheng, Y. Cryo-EM structures of remodeler-nucleosome intermediates suggest allosteric control through the nucleosome. eLife, 2019, 8, e46057. doi: 10.7554/eLife.46057
  159. Sun, H.; Yan, L.; Chang, M.Y.Z.; Carter, K.; Zhang, R.; Slyker, L.; Lovell, J.; Wu, Y.; Cheng, C. A multifunctional biodegradable brush polymer-drug conjugate for paclitaxel/gemcitabine co-delivery and tumor imaging. Nanoscale Advances, 2019, 1(7), 2761–2771. doi: 10.1039/c9na00282k
  160. Zhang, H.; Zhao, J.; Gu, X.; Wen, Y. Targeted treatment of CD22-positive non-Hodgkin's lymphoma with sialic acid–modified chitosan-PLGA hybrid nanoparticles. Journal of Nanoparticle Research, 2019, 21(7), 154. doi: 10.1007/s11051-019-4595-1
  161. Kravchuk, O.I.; Lyupina, Y.V.; Erokhov, P.A.; Finoshin, A.D.; Adameyko, K.I.; Mishyna, M.Y.; Moiseenko, A.V.; Sokolova, O.S.; Orlova, O.V.; Beljelarskaya, S.N.; Serebryakova, M.V.; Indeykina, M.I.; Bugrova, A.E.; Kononikhin, A.S.; Mikhailov, V.S. Characterization of the 20S proteasome of the lepidopteran, Spodoptera frugiperda. Biochimica et Biophysica Acta - Proteins and Proteomics, 2019, 1867(9), 840–853. doi: 10.1016/j.bbapap.2019.06.010
  162. Vinciguerra, D.; Degrassi, A.; Mancini, L.; Mura, S.; Mougin, J.; Couvreur, P.; Nicolas, J. Drug-Initiated Synthesis of Heterotelechelic Polymer Prodrug Nanoparticles for in Vivo Imaging and Cancer Cell Targeting. Biomacromolecules, 2019, 20(7), 2464–2476. doi: 10.1021/acs.biomac.9b00148
  163. Stankowska, D.L.; Nam, M.-H.; Nahomi, R.B.; Chaphalkar, R.M.; Nandi, S.K.; Fudala, R.; Krishnamoorthy, R.R.; Nagaraj, R.H. Systemically administered peptain-1 inhibits retinal ganglion cell death in animal models: implications for neuroprotection in glaucoma. Cell Death Discovery, 2019, 5(1), 112. doi: 10.1038/s41420-019-0194-2
  164. Ni, C.-W.; Wei, Y.-J.; Shen, Y.-I.; Lee, I.-R. Long-Range Hairpin Slippage Reconfiguration Dynamics in Trinucleotide Repeat Sequences. The Journal of Physical Chemistry Letters, 2019, 10, 3985–3990. doi: 10.1021/acs.jpclett.9b01524
  165. Chariou, P.L.; Dogan, A.B.; Welsh, A.G.; Saidel, G.M.; Baskaran, H.; Steinmetz, N.F. Soil mobility of synthetic and virus-based model nanopesticides. Nature Nanotechnology, 2019, 14(7), 712–718. doi: 10.1038/s41565-019-0453-7
  166. Pola, R.; Parnica, J.; Zuska, K.; Böhmová, E.; Filipová, M.; Pechar, M.; Pankrác, J.; Mucksová, J.; Trefil, P.; Kalina, J.; Šefc, L.; Větvička, D.; Poučková, P.; Bouček, J.; Janoušková, O.; Etrych, T. Oligopeptide-targeted polymer nanoprobes for fluorescence-guided endoscopic surgery. Multifunctional Materials, 2019, 2(2), 024004. doi: 10.1088/2399-7532/ab159e
  167. Liu, R.; Li, Z.; Marvin, J.S.; Kleinfeld, D. Direct wavefront sensing enables functional imaging of infragranular axons and spines. Nature Methods, 2019, 16, 615–618. doi: 10.1038/s41592-019-0434-7
  168. Naidu, P.S.R.; Gavriel, N.; Gray, C.G.G.; Bartlett, C.A.; Toomey, L.M.; Kretzmann, J.; Patalwala, D.; McGonigle, T.; Denham, E.; Hee, C.; Ho, D.; Taylor, N.L.; Norret, M.; Smith, N.M.; Dunlop, S.A.; Iyer, K.S.; Fitzgerald, M. Elucidating the Inability of Functionalized Nanoparticles to Cross the Blood–Brain Barrier and Target Specific Cells In Vivo. ACS Applied Materials & Interfaces, 2019, 11(25), 22085–22095. doi: 10.1021/acsami.9b01356
  169. Rippe, M.; Stefanello, T.F.; Kaplum, V.; Britta, E.A.; Garcia, F.P.; Poirot, R.; Companhoni, M.V.P.; Nakamura, C.V.; Szarpak-Jankowska, A.; Auzély-Velty, R. Heparosan as a potential alternative to hyaluronic acid for the design of biopolymer-based nanovectors for anticancer therapy. Biomaterials Science, 2019, 7, 2850–2860. doi: 10.1039/c9bm00443b
  170. Li, W.; Yalcin, M.; Bharali, D.J.; Lin, Q.; Godugu, K.; Fujioka, K.; Keating, K.A.; Mousa, S.A. Pharmacokinetics, Biodistribution, and Anti-Angiogenesis Efficacy of Diamino Propane Tetraiodothyroacetic Acid-conjugated Biodegradable Polymeric Nanoparticle. Scientific Reports, 2019, 9(1), 9006. doi: 10.1038/s41598-019-44979-6
  171. Comerci, C.J.; Herrmann, J.; Yoon, J.; Jabbarpour, F.; Zhou, X.; Nomellini, J.F.; Smit, J.; Shapiro, L.; Wakatsuki, S.; Moerner, W.E. Topologically-guided continuous protein crystallization controls bacterial surface layer self-assembly. Nature Communications, 2019, 10(1), 2731. doi: 10.1038/s41467-019-10650-x
  172. Narayanaswamy, V.P.; Duncan, A.P.; LiPuma, J.J.; Wiesmann, W.P.; Baker, S.M.; Townsend, S.M. In Vitro Activity of a Novel Glycopolymer against Biofilms of Burkholderia cepacia Complex Cystic Fibrosis Clinical Isolates. Antimicrobial Agents and Chemotherapy, 2019, 63(6), e00498-19. doi: 10.1128/AAC.00498-19
  173. Maisel, S.A.; Broka, D.; Atwell, B.; Bunch, T.; Kupp, R.; Singh, S.K.; Mehta, S.; Schroeder, J. Stapled EGFR peptide reduces inflammatory breast cancer and inhibits additional HER-driven models of cancer. Journal of Translational Medicine, 2019, 17, 201. doi: 10.1186/s12967-019-1939-7
  174. Barnett, D.; Hall, J.; Haab, B. Automated identification and quantification of signals in multichannel immunofluorescence images: the SignalFinder platform. The American Journal of Pathology, 2019, 189(7), 1402–1412. doi: 10.1016/j.ajpath.2019.03.011
  175. Olson, C.M.; Liang, Y.; Leggett, A.; Park, W.D.; Li, L.; Mills, C.E.; Elsarrag, S.Z.; Ficarro, S.B.; Zhang, T.; Düster, R.; Geyer, M.; Sim, T.; Marto, J.A.; Sorger, P.K.; Westover, K.D.; Lin, C.Y.; Kwiatkowski, N.; Gray, N.S. Development of a Selective CDK7 Covalent Inhibitor Reveals Predominant Cell-Cycle Phenotype. Cell Chemical Biology, 2019, 26(6), 792–803.e10. doi: 10.1016/j.chembiol.2019.02.012
  176. Zhu, M.; Lu, D.; Wu, S.; Lian, Q.; Wang, W.; Lyon, A.; Wang, W.; Bartolo, P.; Saunders, B.R. Using green emitting pH-responsive nanogels to report environmental changes within hydrogels: A nanoprobe for versatile sensing. Nanoscale, 2019, 11(24), 11484–11495. doi: 10.1039/c9nr00989b
  177. Li, G.; Lei, Q.; Wang, F.; Deng, D.; Wang, S.; Tian, L.; Shen, W.; Cheng, Y.; Liu, Z. Wu, S. Fluorinated Polymer Mediated Transmucosal Peptide Delivery for Intravesical Instillation Therapy of Bladder Cancer. Small, 2019, 15(25), e1900936. doi: 10.1002/smll.201900936
  178. Gournaris, E.; Park, W.; Cho, S.; Bentrem, D.J.; Larson, A.C.; Kim, D.-H. Near-Infrared Fluorescent Endoscopic Image-guided Photothermal Ablation Therapy of Colorectal Cancer using Dual-modal Gold Nanorods Targeting Tumor Infiltrating Innate Immune Cells in Transgenic TS4 CRE/APCloxΔ468 Mouse Model. ACS Applied Materials & Interfaces, 2019, 11(24), 21353–21359. doi: 10.1021/acsami.9b04186
  179. Shi, L.; Qalieh, A.; Lam, M.M.; Keil, J.M.; Kwan, K.Y. Robust elimination of genome-damaged cells safeguards against brain somatic aneuploidy following Knl1 deletion. Nature Communications, 2019, 10, 2588. doi: 10.1038/s41467-019-10411-w
  180. Nevozhay, D.; Weiger, M.; Friedl, P.; Sokolov, K.V. Spatiotemporally controlled nano-sized third harmonic generation agents. Biomedical Optics Express, 2019, 10(7), 3301. doi: 10.1364/boe.10.003301
  181. Liu, R.; Vairaprakash, P.; Lindsey, J.S. Self-assembly with fluorescence readout in a free base dipyrrin–polymer triggered by metal ion binding in aqueous solution. New Journal of Chemistry, 2019, 43(24), 9711–9724. doi: 10.1039/c9nj01787a
  182. Zhao, C.; Liu, A.; Santamaria, C.M.; Shomorony, A.; Ji, T.; Wei, T.; Gordon, A.; Elofsson, H.; Mehta, M.; Yang, R.; Kohane, D.S. Polymer-tetrodotoxin conjugates to induce prolonged duration local anesthesia with minimal toxicity. Nature Communications, 2019, 10, 2566. doi: 10.1038/s41467-019-10296-9
  183. Hu, H.; Petrosyan, A.; Osna, N.A.; Liu, T.; Olou, A.A.; Alakhova, D.Y.; Singh, P.K.; Kabanov, A.V.; Faber, E.A.; Bronich, T.K. Pluronic block copolymers enhance the anti-myeloma activity of proteasome inhibitors. Journal of Controlled Release, 2019, 306, 149–164. doi: 10.1016/j.jconrel.2019.05.026
  184. Dupré-Crochet, S.; Erard, M.; Nüße, O. Kinetic Analysis of Phagosomal ROS Generation. Methods in Molecular Biology, 2019, 1982, 301–312. doi: 10.1007/978-1-4939-9424-3_18
  185. Kang, M.-S.; Ryu, E.; Lee, S.-W.; Park, J.; Ha, N.Y.; Ra, J.S.; Kim, Y.J.; Kim, J.; Abdel-Rahman, M.; Park, S.H.; Lee, K.-Y.; Kim, H.; Kang, S.; Myung, K. Regulation of PCNA cycling on replicating DNA by RFC and RFC-like complexes. Nature Communications, 2019, 10, 2420. doi: 10.1038/s41467-019-10376-w
  186. Guenter, R.E.; Aweda, T.; Carmona Matos, D.M.; Whitt, J.; Chang, A.W.; Cheng, E.Y.; Liu, X.M.; Chen, H.; Lapi, S.E.; Jaskula-Sztul, R. Pulmonary Carcinoid Surface Receptor Modulation Using Histone Deacetylase Inhibitors. Cancers, 2019, 11(6), 767. doi: 10.3390/cancers11060767
  187. Huang, C.; Zeng, T.; Li, J.; Tan, L.; Deng, X.; Pan, Y.; Chen, Q.; Li, A.; Hu, J. Folate Receptor-mediated Renal-targeting Nanoplatform for the Specific Delivery of Triptolide to Treat Renal Ischemia/Reperfusion Injury. ACS Biomaterials Science & Engineering, 2019, 5(6), 2877–2886. doi: 10.1021/acsbiomaterials.9b00119
  188. Ding, Y.; Liu, J.; Li, X.; Xu, L.; Li, C.; Ma, L.; Liu, J.; Ma, R.; An, Y.; Huang, F.; Liu, Y.; Shi, L. Rational design of drug delivery systems for potential programmable drug release and improved therapeutic effect. Materials Chemistry Frontiers, 2019, 3(6), 1159–1167. doi: 10.1039/c9qm00178f
  189. Burla, F.; Tauber, J.; Dussi, S.; van der Gucht, J.; Koenderink, G.H. Stress management in composite biopolymer networks. Nature Physics, 2019, 15(6), 549–553. doi: 10.1038/s41567-019-0443-6
  190. Zhang, S.; Spiegelman, N.A.; Lin, H. Global Profiling of Sirtuin Deacylase Substrates Using a Chemical Proteomic Strategy and Validation by Fluorescent Labeling. Methods in Molecular Biology, 2019, 2009, 137–147. doi: 10.1007/978-1-4939-9532-5_11
  191. Qi, T.; Chen, B.; Wang, Z.; Du, H.; Liu, D.; Yin, Q.; Liu, B.; Zhang, Q.; Wang, Y. A pH-Activatable nanoparticle for dual-stage precisely mitochondria-targeted photodynamic anticancer therapy. Biomaterials, 2019, 213, 119219. doi: 10.1016/j.biomaterials.2019.05.030
  192. Islam, M.S.; Reineke, J.; Kaushik, R.S.; Woyengo, T.; Baride, A.; Alqahtani, M.S.; Perumal, O. Bioadhesive Food-Protein Nanoparticles as Pediatric Oral Drug Delivery system. ACS Applied Materials & Interfaces, 2019, 11(20), 18062–18073. doi: 10.1021/acsami.9b00152
  193. Dahanayake, V.; Pornrungroj, C.; Pablico-Lansigan, M.; Hickling, W.J.; Lyons, T.; Lah, D.; Lee, Y.-C.; Parasido, E.; Bertke, J.A.; Albanese, C.; Rodriguez, O.; Van Keuren, E.; Stoll, S.L. Paramagnetic Clusters of Mn3(O2CCH3)6(Bpy)2 in Polyacrylamide Nanobeads as a New Design Approach to T1-T2 Multi-Modal MRI Contrast Agent. ACS Applied Materials & Interfaces, 2019, 11(20), 18153–18164. doi: 10.1021/acsami.9b03216
  194. Carniato, F.; Alberti, D.; Lapadula, A.; Martinelli, J.; Isidoro, C.; Crich, S.G.; Tei, L. Multifunctional Gd-based mesoporous silica nanotheranostic for anticancer drug delivery. Journal of Materials Chemistry B, 2019, 7(19), 3143–3152. doi: 10.1039/c9tb00375d
  195. Doll, F.; Steimbach, R.; Zumbusch, A. Direct Imaging of Protein-Specific Methylation in Mammalian Cells. Chembiochem, 2019, 20(10), 1315–1325. doi: 10.1002/cbic.201800787
  196. Svenskaya, Y.I.; Genina, E.A.; Parakhonskiy, B.V.; Lengert, E.; Talnikova, E.E.; Terentyuk, G.S.; Utz, S.R.; Gorin, D.A.; Tuchin, V.V.; Sukhorukov, G. A simple non-invasive approach towards efficient transdermal drug delivery based on biodegradable particulate system. ACS Applied Materials & Interfaces, 2019, 11(19), 17270–17282. doi: 10.1021/acsami.9b04305
  197. Crawford, B.M.; Strobbia, P.; Wang, H.-N.; Zentella, R.; Boyanov, M.; Odion, R.; Pei, Z.-M.; Sun, T.-P.; Kemner, K.M.; Vo-Dinh, T. In vivo nucleic acid detection and imaging within whole plants using plasmonic nanosensors. Advanced Environmental, Chemical, and Biological Sensing Technologies XV (Proceedings SPIE 11007), 2019, 11007, 1100708. doi: 10.1117/12.2524840
  198. Wang, H.-N.; Register, J.K.; Fales, A.M.; Gandra, N.; Strobbia, P.; Cho, E.H.; Boico, A.; Palmer, G.M.; Klitzman, B.; Vo-Dinh, T. Implantable "smart tattoo" SERS nanosensors for in vivo detection of nucleic acid biotargets in a large animal model. Plasmonics in Biology and Medicine XVI (Proceedings SPIE 10894), 2019, 108941J. doi: 10.1117/12.2514634
  199. Nojoumi, S.; Ma, Y.; Schwagerus, S.; Hackenberger, C.P.R.; Budisa, N. In-Cell Synthesis of Bioorthogonal Alkene Tag S-Allyl-Homocysteine and Its Coupling with Reprogrammed Translation. International Journal of Molecular Sciences, 2019, 20(9), 2299. doi: 10.3390/ijms20092299
  200. De France, K.J.; Badv, M.; Dorogin, J.; Siebers, E.; Panchal, V.; Babi, M.; Moran-Mirabal, J.; Lawlor, M.; Cranston, E.D.; Hoare, T. Tissue Response and Biodistribution of Injectable Cellulose Nanocrystal Composite Hydrogels. ACS Biomaterials Science & Engineering, 2019, 5(5), 2235–2246. doi: 10.1021/acsbiomaterials.9b00522
  201. Mo, Y.; Du, H.; Chen, B.; Liu, D.; Yin, Q.; Yan, Y.; Wang, Z.; Wan, F.; Qi, T.; Wang, Y.; Zhang, Q.; Wang, Y. Quick-Responsive Polymer-Based Thermo-Sensitive Liposomes for Controlled Doxorubicin Release and Chemotherapy. ACS Biomaterials Science & Engineering, 2019, 5(5), 2316–2329. doi: 10.1021/acsbiomaterials.9b00343
  202. Wang, S. Single Molecule RNA FISH smFISH in Whole-Mount Mouse Embryonic Organs. Current Protocols in Cell Biology, 2019, 83(1), e79. doi: 10.1002/cpcb.79
  203. Kasprzyk, R.; Starek, B.J.; Ciechanowicz, S.; Kubacka, D.; Kowalska, J.; Jemielity, J. Fluorescent turn-on probes for the development of binding and hydrolytic activity assays for mRNA cap-recognising proteins. Chemistry, 2019, 25(27), 6728–6740. doi: 10.1002/chem.201900051
  204. Zhang, C.Y.; Lin, W.; Gao, J.; Shi, X.; Davaritouchaee, M.; Nielsen, A.E.; Mancini, R.J.; Wang, Z. pH-Responsive Nanoparticles Targeted to Lungs for Improved Therapy of Acute Lung Inflammation/Injury. ACS Applied Materials & Interfaces, 2019, 11(18), 16380–16390. doi: 10.1021/acsami.9b04051
  205. Cohen, J.; Raviv, S.; Adir, O.; Padmanabhan, K.; Soffer, A.; Luxenburg, C. The Wave complex controls epidermal morphogenesis and proliferation by suppressing Wnt-Sox9 signaling. Journal of Cell Biology, 2019, 218(4), 1390–1406. doi: 10.1083/jcb.201807216
  206. Sauer, F.; Klemm, T.; Kollampally, R.B.; Tessmer, I.; Nair, R.K.; Popov, N.; Kisker, C. Differential Oligomerization of the Deubiquitinases USP25 and USP28 Regulates Their Activities. Molecular Cell, 2019, 74(3), 421–435.e10. doi: 10.1016/j.molcel.2019.02.029
  207. Tischer, D.K.; Weiner, O.D. Light-based tuning of ligand half-life supports kinetic proofreading model of T cell signaling. eLIFE, 2019, 8, e42489. doi: 10.7554/eLife.42498
  208. Chan, P.S.; Xian, J.W.; Li, Q.; Chan, C.W.; Leung, S.S.Y.; To, K.K.W. Biodegradable Thermosensitive PLGA-PEG-PLGA Polymer for Non-irritating and Sustained Ophthalmic Drug Delivery. AAPS Journal, 2019, 21, 59. doi: 10.1208/s12248-019-0326-x
  209. Kashfi-Sadabad, R.; Gonzalez-Fajardo, L.; Hargrove, D.; Ahmadi, B:, Munteanu, D.; Shahbazmohamadi, S.; Jay, M.; Lu, X. Engineering Multifunctional Gold Decorated Dendritic Mesoporous Silica/Tantalum Oxide Nanoparticles for Intraperitoneal Tumor-Specific Delivery. Particle & Particle Systems Characterization, 2019, 36(4), 1900058. doi: 10.1002/ppsc.201900058
  210. Yang, H.; Sukamtoh, E.; Du, Z.; Wang, W.; Ando, M.; Kwakwa, Y.N.; Zhang, J.; Zhang, G. Click chemistry approach to characterize curcumin-protein interactions in vitro and in vivo}. The Journal of Nutritional Biochemistry, 2019, 68, 1–6. doi: 10.1016/j.jnutbio.2019.02.010
  211. Guo, S.; Xiao, X.; Wang, X.; Luo, Q.; Zhu, H.; Zhang, H.; Li, H.; Gong, Q.; Luo, K. Reductive microenvironment responsive gadolinium-based polymers as potential safe MRI contrast agents. Biomaterials Science, 2019, 7(5), 1919–1932. doi: 10.1039/c8bm01103f
  212. Erel-Akbaba, G.; Carvalho, L.A.; Tian, T.; Zinter, M.; Akbaba, H.; Obeid, P.J.; Chiocca, E.A.; Weissleder, R.; Kantarci, A.G.; Tannous, B.A. Radiation-Induced Targeted Nanoparticle-Based Gene Delivery for Brain Tumor Therapy. ACS Nano, 2019, 13(4), 4028–4040. doi: 10.1021/acsnano.8b08177
  213. Mildažienė, Vida and Aleknavičiūtė, V.; Žūkienė, R.; Paužaitė, G.; Naučienė, Z.; Filatova, I.; Lyushkevich, V.; Haimi, P.; Tamošiūnė, I.; Baniulis, D. Treatment of Common Sunflower (Helianthus annus L.) Seeds with Radio-frequency Electromagnetic Field and Cold Plasma Induces Changes in Seed Phytohormone Balance, Seedling Development and Leaf Protein Expression. Scientific Reports, 2019, 9, 6437. doi: 10.1038/s41598-019-42893-5
  214. Liu, W.; Zhao, W.; Bai, X.; Jin, S.; Li, Y.; Qiu, C.; Pan, L.; Ding, D.; Xu, Y.; Zhou, Z.; Chen, S. High antitumor activity of Sortase A-generated anti-CD20 antibody fragment drug conjugates. European Journal of Pharmaceutical Sciences, 2019, 134, 81–92. doi: 10.1016/j.ejps.2019.04.015
  215. Tang, G.; Liu, L.; Wang, X.; Pan, Z. Discovery of 7H-pyrrolo[2,3-d]pyrimidine derivatives as selective covalent irreversible inhibitors of interleukin-2-inducible T-cell kinase (Itk). European Journal of Medicinal Chemistry, 2019, 173, 167–183. doi: 10.1016/j.ejmech.2019.03.055
  216. Kholmicheva, N.; Budkina, D.S.; Cassidy, J.; Porotnikov, D.; Harankahage, D.; Boddy, A.; Galindo, M.; Khon, D.; Tarnovsky, A.N.; Zamkov, M. Sustained Biexciton Populations in Nanoshell Quantum Dots. ACS Photonics, 2019, 6(4), 1041–1050. doi: 10.1021/acsphotonics.9b00068
  217. Zemella, A.; Richter, T.; Thoring, L.; Kubick, S. A Combined Cell-Free Protein Synthesis and Fluorescence-Based Approach to Investigate GPCR Binding Properties. Methods in Molecular Biology, 2019, 1947, 57–77. doi: 10.1007/978-1-4939-9121-1_4
  218. Diaz-Salmeron, R.; Ponchel, G.; Bouchemal, K. Hierarchically built hyaluronic nano-platelets have symmetrical hexagonal shape, flattened surfaces and controlled size. European Journal of Pharmaceutical Sciences, 2019, 133, 251–263. doi: 10.1016/j.ejps.2019.04.007
  219. Singh, R.K.; Fan, J.; Gioacchini, N.; Watanabe, S.; Bilsel, O.; Peterson, C.L. Transient Kinetic Analysis of SWR1C-Catalyzed H2A.Z Deposition Unravels the Impact of Nucleosome Dynamics and the Asymmetry of Histone Exchange. Cell Reports, 2019, 27, 374–386.e4. doi: 10.1016/j.celrep.2019.03.035
  220. Phillips, H.R.; Tolstyka, Z.P.; Hall, B.C.; Hexum, J.K.; Hackett, P.B.; Reineke, T.M. Glycopolycation-DNA Polyplex Formulation N/P Ratio Affects Stability, Hemocompatibility, and in Vivo Biodistribution. Biomacromolecules, 2019, 20(4), 1530–1544. doi: 10.1021/acs.biomac.8b01704
  221. Lo, C.-W.; Kryvalap, Y.; Sheu, T.-J.; Chang, C.-H.; Czyzyk, J. Cellular proliferation in mouse and human pancreatic islets is regulated by serpin B13 inhibition and downstream targeting of E-cadherin by cathepsin L. Diabetologia, 2019, 62(5), 822–834. doi: 10.1007/s00125-019-4834-0
  222. Spinelli, A.; Girelli, M.; Arosio, D.; Polito, L.; Podini, P.; Martino, G.; Seneci, P.; Muzio, L.; Menegon, A. Intracisternal delivery of PEG-coated gold nanoparticles results in high brain penetrance and long-lasting stability. Journal of Nanobiotechnology, 2019, 17, 49. doi: 10.1186/s12951-019-0481-3
  223. Steinmetz, H.P.; Rudnick-Glick, S.; Natan, M.; Banin, E.; Margel, S. Poly(styryl bisphosphonate) nanoparticles with a narrow size distribution: Synthesis, characterization and antibacterial applications. European Polymer Journal, 2019, 116, 65–73. doi: 10.1016/j.eurpolymj.2019.04.007
  224. Feczkó, T.; Merza, G.; Babos, G.; Varga, B.; Gyetvai, E.; Trif, L.; Kovács, E.; Tuba, R. Preparation of cubic-shaped sorafenib-loaded nanocomposite using well-defined poly(vinyl alcohol alt-propenylene) copolymer. International Journal of Pharmaceutics, 2019, 562, 333–341. doi: 10.1016/j.ijpharm.2019.03.008
  225. Rojas-Sánchez, L.; Sokolova, V.; Riebe, S.; Voskuhl, J.; Epple, M. Covalent Surface Functionalization of Calcium Phosphate Nanoparticles with Fluorescent Dyes by Copper-Catalysed and by Strain-Promoted Azide-Alkyne Click Chemistry. ChemNanoMat, 2019, 5(4), 436–446. doi: 10.1002/cnma.201800509
  226. Cho, H.-J.; Lee, S.; Park, S.-J.; Lee, Y.-D.; Jeong, K.; Park, J.H.; Lee, Y.-S.; Kim, B.; Jeong, H.-S.; Kim, S. Tumor microenvironment-responsive fluorogenic nanoprobe for ratiometric dual-channel imaging of lymph node metastasis. Colloids and Surfaces B, 2019, 179, 9–16. doi: 10.1016/j.colsurfb.2019.03.047
  227. Lin, P.-Y.; Chen, K.-H.; Miao, Y.-B.; Chen, H.-L.; Lin, K.-J.; Chen, C.-T.; Yeh, C.-N.; Chang, Y.; Sung, H.-W. Phase-Changeable Nanoemulsions for Oral Delivery of a Therapeutic Peptide: Toward Targeting the Pancreas for Antidiabetic Treatments Using Lymphatic Transport. Advanced Functional Materials, 2019, 29(13), 1809015. doi: 10.1002/adfm.201809015
  228. Zhang, Y.; Zhu, X.; Chen, X.; Chen, Q.; Zhou, W.; Guo, Q.; Lu, Y.; Li, C.; Zhang, Y.; Liang, D.; Sun, T.; Wei, X.; Jiang, C. Activated Platelets-Targeting Micelles with Controlled Drug Release for Effective Treatment of Primary and Metastatic Triple Negative Breast Cancer. Advanced Functional Materials, 2019, 29(13), 1806620. doi: 10.1002/adfm.201806620
  229. Howard, G.P.; Verma, G.; Ke, X.; Thayer, W.M.; Hamerly, T.; Baxter, V.K.; Lee, J.E.; Dinglasan, R.R.; Mao, H.-Q. Critical size limit of biodegradable nanoparticles for enhanced lymph node trafficking and paracortex penetration. Nano Research, 2019, 12(4), 837–844. doi: 10.1007/s12274-019-2301-3
  230. Wild, A.R.; Sinnen, B.L.; Dittmer, P.J.; Kennedy, M.J.; Sather, W.A.; Dell'Acqua, M.L. Synapse-to-Nucleus Communication through NFAT Is Mediated by L-type Ca2+ Channel Ca2+ Spike Propagation to the Soma. Cell Reports, 2019, 26, 3537–3550.e4. doi: 10.1016/j.celrep.2019.03.005
  231. Simon, Á.; Gulyás, G.; Mészár, Z.; Bhide, M.; Oláh, J.; Bai, P.; Csősz, É.; Jávor, A.; Komlósi, I.; Remenyik, J.; Czeglédi, L. Proteomics alterations in chicken jejunum caused by 24 h fasting. PeerJ, 2019, 7, e6588. doi: 10.7717/peerj.6588
  232. Liang, S.; Guan, Y.; Zhang, Y. Layer-by-Layer Assembly of Microgel Colloidal Crystals via Photoinitiated Alkyne–Azide Click Reaction. ACS Omega, 2019, 4(3), 5650–5660. doi: 10.1021/acsomega.9b00354
  233. Zheng, L.; Zhao, H.; Han, Y.; Qian, H.; Vukovic, L.; Mecinović, J.; Král, P.; Huck, W.T.S. Catalytic transport of molecular cargo using diffusive binding along a polymer track. Nature Chemistry, 2019, 11(4), 359–366. doi: 10.1038/s41557-018-0204-7
  234. Saito, E.; Kuo, R.; Pearson, R.M.; Gohel, N.; Cheung, B.; King, N.J.C.; Miller, S.D.; Shea, L.D. Designing drug-free biodegradable nanoparticles to modulate inflammatory monocytes and neutrophils for ameliorating inflammation. Journal of Controlled Release, 2019, 300, 185–196. doi: 10.1016/j.jconrel.2019.02.025
  235. He, Z.; Hu, Y.; Gui, Z.; Zhou, Y.; Nie, T.; Zhu, J.; Liu, Z.; Chen, K.; Liu, L.; Leong, K.W.; Cao, P.; Chen, Y.; Mao, H.-Q. Sustained release of exendin-4 from tannic acid/Fe (III) nanoparticles prolongs blood glycemic control in a mouse model of type II diabetes. Journal of Controlled Release, 2019, 301, 119–128. doi: 10.1016/j.jconrel.2019.03.014
  236. Laberge, A.; Ayoub, A.; Arif, S.; Larochelle, S.; Garnier, A.; Moulin, V.J. α-2-Macroglobulin induces the shedding of microvesicles from cutaneous wound myofibroblasts. Journal of Cellular Physiology, 2019, 234(7), 11369–11379. doi: 10.1002/jcp.27794
  237. Kam, A.; Loo, S.; Dutta, B.; Sze, S.K.; Tam, J.P. Plant-derived mitochondria-targeting cysteine-rich peptide modulates cellular bioenergetics. Journal of Biological Chemistry, 2019, 294(11), 4000–4011. doi: 10.1074/jbc.RA118.006693
  238. Xiao, C.; Hu, H.; Yang, H.; Li, S.; Zhou, H.; Ruan, J.; Zhu, Y.; Yang, X.; Li, Z. Colloidal hydroxyethyl starch for tumor-targeted platinum delivery. Nanoscale Advances, 2019, 1(3), 1002–1012. doi: 10.1039/c8na00271a
  239. Crawford, T.; Fletcher, N.; Veitch, M.; Gonzalez Cruz, J.L.; Pett, N.; Brereton, I.; Wells, J.W.; Mobli, M.; Tesiram, Y. Bacillus anthracis Protective Antigen Shows High Specificity for a UV Induced Mouse Model of Cutaneous Squamous Cell Carcinoma. Frontiers in Medicine, 2019, 6, 22. doi: 10.3389/fmed.2019.00022
  240. Wilder, L.M.; Fies, W.A.; Rabin, C.; Webb, L.J.; Crooks, R.M. Conjugation of an α-Helical Peptide to the Surface of Gold Nanoparticles. Langmuir, 2019, 35(9), 3363–3371. doi: 10.1021/acs.langmuir.9b00075
  241. Reyes-Ruiz, J.M.; Osuna-Ramos, J.F.; Bautista-Carbajal, P.; Jaworski, E.; Soto-Acosta, R.; Cervantes-Salazar, M.; Angel-Ambrocio, A.H.; Castillo-Munguía, J.P.; Chávez-Munguía, B.; De Nova-Ocampo, M.; Routh, A.; del Ángel, R.M.; Salas-Benito, J.S. Mosquito cells persistently infected with dengue virus produce viral particles with host-dependent replication. Virology, 2019, 531, 1–18. doi: 10.1016/j.virol.2019.02.018
  242. Shen, Y.; Yang, S.; Hu, X.; Zhang, M.; Ma, X.; Wang, Z.; Hou, Y.; Bai, G. Natural product puerarin activates Akt and ameliorates glucose and lipid metabolism dysfunction in hepatic cells. Journal of Functional Foods, 2019, 55, 296–304. doi: 10.1016/j.jff.2019.02.035
  243. Reichart, F.; Maltsev, O.V.; Kapp, T.G.; Räder, A.F.B.; Weinmüller, M.; Marelli, U.K.; Notni, J.; Wurzer, A.; Beck, R.; Wester, H.-J.; Steiger, K.; Di Maro, S.; Di Leva, F.S.; Marinelli, L.; Nieberler, M.; Reuning, U.; Schwaiger, M.; Kessler, H. Selective Targeting of Integrin αvβ8 by a Highly Active Cyclic Peptide. Journal of Medicinal Chemistry, 2019, 62(4), 2024–2037. doi: 10.1021/acs.jmedchem.8b01588
  244. Le, D.H.T.; Commandeur, U.; Steinmetz, N.F. Presentation and Delivery of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand via Elongated Plant Viral Nanoparticle Enhances Antitumor Efficacy. ACS Nano, 2019, 13(2), 2501–2510. doi: 10.1021/acsnano.8b09462
  245. Crawford, B.M.; Strobbia, P.; Wang, H.-N.; Zentella, R.; Boyanov, M.I.; Pei, Z.-M.; Sun, T.-P.; Kemner, K.M.; Vo-Dinh, T. Plasmonic nanoprobes for in vivo multimodal sensing and bioimaging of microRNA within plants. ACS Applied Materials & Interfaces, 2019, 11(8), 7743–7754. doi: 10.1021/acsami.8b19977
  246. Dong, B.; Du, S.; Wang, C.; Fu, H.; Li, Q.; Xiao, N.; Yang, J.; Xue, X.; Cai, W.; Liu, D. Reversible Self-Assembly of Nanoprobes in Live Cells for Dynamic Intracellular pH Imaging. ACS Nano, 2019, 13(2), 1421–1432. doi: 10.1021/acsnano.8b07054
  247. Feltes, M.; Moores, S.; Gale, S.E.; Krishnan, K.; Mydock-McGrane, L.; Covey, D.F.; Ory, D.S.; Schaffer, J.E. Synthesis and characterization of diazirine alkyne probes for the study of intracellular cholesterol trafficking. Journal of Lipid Research, 2019, 60(3), 707–716. doi: 10.1194/jlr.D091470
  248. Guo, A.; Durymanov, M.; Permyakova, A.; Sene, S.; Serre, C.; Reineke, J. . Metal Organic Framework (MOF) Particles as Potential Bacteria-Mimicking Delivery Systems for Infectious Diseases: Characterization and Cellular Internalization in Alveolar Macrophages, 2019, 36, 53. doi: 10.1007/s11095-019-2589-4
  249. Yang, C.; Liu, D.; Renny, A.; Kuttipillai, P.S.; Lunt, R.R. Integration of near-infrared harvesting transparent luminescent solar concentrators onto arbitrary surfaces. Journal of Luminescence, 2019, 210, 239–246. doi: 10.1016/j.jlumin.2019.02.042
  250. Guo, J.; Mingoes, C.; Qiu, X.; Hildebrandt, N. Simple, Amplified, and Multiplexed Detection of MicroRNAs Using Time-Gated FRET and Hybridization Chain Reaction. Analytical Chemistry, 2019, 91(4), 3101–3109. doi: 10.1021/acs.analchem.8b05600
  251. Elrod, N.R.; Jaworski, E.A.; Ji, P.; Wagner, E.J.; Routh, A. Development of Poly(A)-ClickSeq as a Tool Enabling Simultaneous Genome-wide Poly(A)-site identification and Differential Expression Analysis. Methods, 2019, 155, 20–29. doi: 10.1016/j.ymeth.2019.01.002
  252. Madl, C.M.; LeSavage, B.L.; Dewi, R.E.; Lampe, K.J.; Heilshorn, S.C. Matrix Remodeling Enhances the Differentiation Capacity of Neural Progenitor Cells in 3D Hydrogels. Advanced Science, 2019, 6(4), 1801716. doi: 10.1002/advs.201801716
  253. De France, K.J.; Babi, M.; Vapaavuori, J.; Hoare, T.; Moran-Mirabal, J.M.; Cranston, E.D. 2.5D Hierarchical Structuring of Nanocomposite Hydrogel Films Containing Cellulose Nanocrystals. ACS Applied Materials & Interfaces, 2019, 11(6), 6325–6335. doi: 10.1021/acsami.8b16232
  254. Liu, X.; Nemeth, D.P.; McKim, D.B.; Zhu, L.; DiSabato, D.J.; Berdysz, O.; Gorantla, G.; Oliver, B.; Witcher, K.G.; Wang, Y.; Negray, C.E.; Vegesna, R.S.; Sheridan, J.F.; Godbout, J.P.; Robson, M.J.; Blakely, R.D.; Popovich, P.G.; Bilbo, S.D.; Quan, N. Cell-Type-Specific Interleukin 1 Receptor 1 Signaling in the Brain Regulates Distinct Neuroimmune Activities. Immunity, 2019, 50(2), 317–333.e6. doi: 10.1016/j.immuni.2018.12.012
  255. Du, T.; Buenbrazo, N.; Kell, L.; Rahmani, S.; Sim, L.; Withers, S.G.; DeFrees, S.; Wakarchuk, W.;. A Bacterial Expression Platform for Production of Therapeutic Proteins Containing Human-like O-Linked Glycans. Cell Chemical Biology, 2019, 26(2), 203–212.e5. doi: 10.1016/j.chembiol.2018.10.017
  256. Gagni, P.; Romanato, A.; Bergamaschi, G.; Bettotti, P.; Vanna, R.; Piotto, C.; Morasso, C.F.; Chiari, M.; Cretich, M.; Gori, A. A self-assembling peptide hydrogel for ultrarapid 3D bioassays. Nanoscale Advances, 2019, 1(2), 490–497. doi: 10.1039/c8na00158h
  257. Lee, M.-R.; Raman, N.; Ortiz-Bermúdez, P.; Lynn, D.M.; Palecek, S.P. 14-Helical β-Peptides Elicit Toxicity against C. albicans by Forming Pores in the Cell Membrane and Subsequently Disrupting Intracellular Organelles. Cell Chemical Biology, 2019, 26(2), 289–299.e4. doi: 10.1016/j.chembiol.2018.11.002
  258. Tesarova, B.; Charousova, M.; Dostalova, S.; Bienko, A.; Kopel, P.; Kruszyński, R.; Hynek, D.; Michalek, P.; Eckschlager, T.; Stiborova, M.; Adam, V.; Heger, Z. Folic acid-mediated re-shuttling of ferritin receptor specificity towards a selective delivery of highly cytotoxic nickel(II) coordination compounds. International Journal of Biological Macromolecules, 2019, 126, 1099–1111. doi: 10.1016/j.ijbiomac.2018.12.128
  259. Zhang, H.; Wu, J.; Wu, J.; Fan, Q.; Zhou, J.; Wu, J.; Liu, S.; Zang, J.; Ye, J.; Xiao, M.; Tian, T.; Gao, J. Exosome-mediated targeted delivery of miR-210 for angiogenic therapy after cerebral ischemia in mice. Journal of Nanobiotechnology, 2019, 17, 29. doi: 10.1186/s12951-019-0461-7
  260. Tobola, F.; Sylvander, E.; Gafko, C.; Wiltschi, B. `Clickable lectins': bioorthogonal reactive handles facilitate the directed conjugation of lectins in a modular fashion. Interface Focus, 2019, 9(2), 20180072. doi: 10.1098/rsfs.2018.0072
  261. Cao, P.; Wei, X.; Awal, R.P.; Müller, R.; Wall, D. A Highly Polymorphic Receptor Governs Many Distinct Self-Recognition Types within the Myxococcales Order. mBio, 2019, 10, e02751-18. doi: 10.1128/mBio.02751-18
  262. Shim, G.; Le, Q.-V.; Suh, J.; Choi, S.; Kim, G.; Choi, H.-G.; Kim, Y.B.; Macgregor, M.B.; Oh, Y.-K. Sequential activation of anticancer therapy triggered by tumor microenvironment-selective imaging. Journal of Controlled Release, 2019, 298, 110–119. doi: 10.1016/j.jconrel.2019.02.012
  263. Vishnu Vardhan, G.P.; Hema, M.; Sushmitha, C.; Savithri, H.S.; Natraj, U.; Murthy, M.R.N. Development of sesbania mosaic virus nanoparticles for imaging. Archives of Virology, 2019, 164(2), 497–507. doi: 10.1007/s00705-018-4097-y
  264. Chen, Y.; Fan, H.; Xu, C.; Hu, W.; Yu, B. Efficient Cholera Toxin B Subunit-Based Nanoparticles with MRI Capability for Drug Delivery to the Brain Following Intranasal Administration. Macromolecular Bioscience, 2019, 19(2), 1800340. doi: 10.1002/mabi.201800340
  265. Gu, W.; Bobrin, V.A.; Chen, S.-P.R.; Wang, Z.; Schoning, J.P.; Gu, Y.; Chen, W.; Chen, M.; Jia, Z.; Monteiro, M.J. Biodistribution of PNIPAM-Coated Nanostructures Synthesized by the TDMT Method. Biomacromolecules, 2019, 20(2), 625–634. doi: 10.1021/acs.biomac.8b01196
  266. Sun, H.; Yan, L.; Carter, K.A.; Zhang, J.; Caserto, J.; Lovell, J.F.; Wu, Y.; Cheng, C. Zwitterionic Crosslinked Biodegradable Nanocapsules for Cancer Imaging. Langmuir, 2019, 35(5), 1440–1449. doi: 10.1021/acs.langmuir.8b01633
  267. Hou, W.; Li, Y.; Kang, W.; Wang, X.; Wu, X.; Wang, S.; Liu, F. Real-time analysis of quantum dot labeled single porcine epidemic diarrhea virus moving along the microtubules using single particle tracking. Scientific Reports, 2019, 9, 1307. doi: 10.1038/s41598-018-37789-9
  268. Wilson, D.R.; Rui, Y.; Siddiq, K.; Routkevitch, D.; Green, J.J. Differentially Branched Ester Amine Quadpolymers with Amphiphilic and pH Sensitive Properties for Efficient Plasmid DNA Delivery. Molecular Pharmaceutics, 2019, 16(2), 655–668. doi: 10.1021/acs.molpharmaceut.8b00963
  269. Kuznetsov, A.E.; Komarova, N.V.; Kuznetsov, E.V.; Andrianova, M.S.; Grudtsov, V.P.; Rybachek, E.N.; Puchnin, K.V.; Ryazantsev, D.V.; Saurov, A.N. Integration of a field effect transistor-based aptasensor under a hydrophobic membrane for bioelectronic nose applications. Biosensors and Bioelectronics, 2019, 129, 29–35. doi: 10.1016/j.bios.2019.01.013
  270. Ni, Y.; Arts, R.; Merkx, M. Ratiometric bioluminescent sensor proteins based on intramolecular split luciferase complementation. ACS Sensors, 2019, 4(1), 20–25. doi: 10.1021/acssensors.8b01381
  271. Hortelao, A.C.; Carrascosa, R.; Murillo-Cremaes, N.; Patiño, T.; Sanchez, S. Targeting 3D Bladder Cancer Spheroids with Urease-Powered Nanomotors. ACS Nano, 2019, 13(1), 429–439. doi: 10.1021/acsnano.8b06610
  272. Liu, Y.; Li, Q.; Xiong, X.; Zhou, Z. Improved mitochondrial targeting effect of HPMA copolymer by SS20 peptide mediation and nonendocytosis pathway. Journal of Peptide Science, 2019, 25(2), e4133. doi: 10.1002/psc.3144
  273. Kwon, Y.-D.; Oh, J.-M.; La, M.T.; Chung, H.-J.; Lee, S.J.; Chun, S.; Lee, S.-H.; Jeong, B.-H.; Kim, H.-K. Synthesis and Evaluation of Multifunctional Fluorescent Inhibitors with Synergistic Interaction of PSMA and Hypoxia for Prostate Cancer. Bioconjugate Chemistry, 2019, 30(1), 90–100. doi: 10.1021/acs.bioconjchem.8b00767
  274. Zhang, X.; Shi, H.; Zhang, R.; Zhang, J.; Xu, F.; Qiao, L.; Yu, S. The Competitive Dynamic Binding of Some Blood Proteins Adsorbed on Gold Nanoparticles. Particle & Particle Systems Characterization, 2019, 36(1), 1800257. doi: 10.1002/ppsc.201800257
  275. Cooper, C.E.; Silkstone, G.G.A.; Simons, M.; Rajagopal, B.; Syrett, N.; Shaik, T.; Gretton, S.; Welbourn, E.; Bülow, L.; Eriksson, N.L.; Ronda, L.; Mozzarelli, A.; Eke, A.; Mathe, D.; Reeder, B.J. Engineering Tyrosine Residues into Hemoglobin Enhances Heme Reduction, Decreases Oxidative Stress and Increases Vascular Retention of a Hemoglobin Based Blood Substitute. Free Radical Biology & Medicine, 2019, 134, 106–118. doi: 10.1016/j.freeradbiomed.2018.12.030
  276. Le, D.H.T.; Méndez-López, E.; Wang, C.; Commandeur, U.; Aranda, M.A.; Steinmetz, N.F. Biodistribution of Filamentous Plant Virus Nanoparticles: Pepino Mosaic Virus versus Potato Virus X. Biomacromolecules, 2019, 20(1), 469–477. doi: 10.1021/acs.biomac.8b01365
  277. Pirutin, S.K.; Efremova, M.V.; Yusipovich, A.I.; Turovetskii, V.B.; Maksimov, G.V.; Druzhko, A.B.; Mazhuga, A.G. Visualization and Cytotoxicity of Fluorescence-Labeled Dimeric Magnetite-Gold Nanoparticles Conjugated with Prostate-Specific Membrane Antigen in Mouse Macrophages. Bulletin of Experimental Biology and Medicine, 2019, 166(3), 386–389. doi: 10.1007/s10517-019-04356-9
  278. Nguyen, H.T.; Soe, Z.C.; Yang, K.Y.; Phung, C.D.; Nguyen, L.T-T.; Jeong, J.-H.; Jin, S.G.; Choi, H.-G.; Ku, S.K.; Yong, C.S.; Kim, J.O. Transferrin-conjugated pH-sensitive platform for effective delivery of porous palladium nanoparticles and paclitaxel in cancer treatment. Colloids and Surfaces, B: Biointerfaces, 2019, 176, 265–275. doi: 10.1016/j.colsurfb.2019.01.010
  279. Maerle, A.V.; Simonova, M.A.; Pivovarov, V.D.; Voronina, D.V.; Drobyazina, P.E.; Trofimov, D.Y.; Alekseev, L.P.; Zavriev, S.K.; Ryazantsev, D.Y. Development of the covalent antibody-DNA conjugates technology for detection of IgE and IgM antibodies by immuno-PCR. PloS One, 2019, 14(1), e0209860. doi: 10.1371/journal.pone.0209860
  280. Marín-Caba, L.; Chariou, P.L.; Pesquera, C.; Correa-Duarte, M.A.; Steinmetz, N.F. Tobacco Mosaic Virus-Functionalized Mesoporous Silica Nanoparticles, a Wool-Ball-like Nanostructure for Drug Delivery. Langmuir, 2019, 35(1), 203–211. doi: 10.1021/acs.langmuir.8b03337
  281. Lalonde, T.; Shepherd, T.G.; Dhanvantari, S.; Luyt, L.G. Stapled ghrelin peptides as fluorescent imaging probes. Peptide Science, 2019, 111(1), e24055. doi: 10.1002/pep2.24055
  282. Liu, Y.; Wang, Z.; Li, X.; Ma, X.; Wang, S.; Kang, F.; Yang, W.; Ma, W.; Wang, J. Near-infrared Fluorescent Peptides with High Tumor Selectivity: Novel Probes for Image-Guided Surgical Resection of Orthotopic Glioma. Molecular Pharmaceutics, 2019, 16(1), 108–117. doi: 10.1021/acs.molpharmaceut.8b00888
  283. Zhang, S.; Li, Z.-T.; Liu, M.; Wang, J.-R.; Xu, M.-Q.; Li, Z.-Y.; Duan, X.-C.; Hao, Y.-L.; Zheng, X.-C.; Li, H.; Feng, Z.-H.; Zhang, X. Anti-tumour activity of low molecular weight heparin doxorubicin nanoparticles for histone H1 high-expressive prostate cancer PC-3M cells. Journal of Controlled Release, 2019, 295, 102–117. doi: 10.1016/j.jconrel.2018.12.034
  284. Kluender, E.J.; Hedrick, J.L.; Brown, K.A.; Rao, R.; Meckes, B.; Du, J.S.; Moreau, L.M.; Maruyama, B.; Mirkin, C.A. Catalyst discovery through megalibraries of nanomaterials. Proceedings of the National Academy of Sciences of the United States of America, 2019, 116(1), 40–45. doi: 10.1073/pnas.1815358116
  285. Li, Y.; Lu, A.; Long, M.; Cui, L.; Chen, Z.; Zhu, L. Nitroimidazole derivative incorporated liposomes for hypoxia-triggered drug delivery and enhanced therapeutic efficacy in patient-derived tumor xenografts. Acta Biomaterialia, 2019, 83, 334–348. doi: 10.1016/j.actbio.2018.10.029
  286. Hauser-Kawaguchi, A.; Milne, M.; Li, F.; Lee, T.Y.; Luyt, L.G. The development of a near infrared inulin optical probe for measuring glomerular filtration rate. International Journal of Biological Macromolecules, 2019, 123, 255–260. doi: 10.1016/j.ijbiomac.2018.11.034
  287. Li, L.; Yang, J.; Soodvilai, S.; Wang, J.; Opanasopit, P.; Kopeček, J. Drug-free albumin-triggered sensitization of cancer cells to anticancer drugs. Journal of Controlled Release, 2019, 293, 84–93. doi: 10.1016/j.jconrel.2018.11.015
  288. Näkki, S.; Wang, J.T.-W.; Wu, J.; Fan, L.; Rantanen, J.; Nissinen, T.; Kettunen, M.I.; Backholm, M.; Ras, R.H.A.; Al-Jamal, K.T.; Lehto, V.-P.; Xu, W. Designed inorganic porous nanovector with controlled release and MRI features for safe administration of doxorubicin. International Journal of Pharmaceutics, 2019, 554, 327–336. doi: 10.1016/j.ijpharm.2018.10.074
  289. Song, J.Y.; Larson, N.R.; Thati, S.; Torres-Vazquez, I.; Martinez-Rivera, N.; Subelzu-Aispuru, N.J.; Leon, M.A.; Rosa-Molinar, E.; Schöneich, C.; Middaugh, C.R.; Berkland, C.J. Glatiramer acetate persists at the injection site and draining lymph nodes via electrostatically-induced aggregation. Journal of Controlled Release, 2019, 293, 36–47. doi: 10.1016/j.jconrel.2018.11.007
  290. Farzan, V.M.; Kvach, M.V.; Aparin, I.O.; Kireev, D.E.; Prikazchikova, T.A.; Ustinov, A.V.; Shmanai, V.V.; Shipulin, G.A.; Korshun, V.A.; Zatsepin, T.S. Novel homo Yin-Yang probes improve sensitivity in RT-qPCR detection of low copy HIV RNA. Talanta, 2019, 194, 226–232. doi: 10.1016/j.talanta.2018.10.043
  291. Li, Y.; Xiao, Y.; Lin, H.-P.; Reichel, D.; Bae, Y.; Lee, E.Y.; Jiang, Y.; Huang, X.; Yang, C.; Wang, Z. In vivo β-catenin attenuation by the integrin α5-targeting nano-delivery strategy suppresses triple negative breast cancer stemness and metastasis. Biomaterials, 2019, 188, 160–172. doi: 10.1016/j.biomaterials.2018.10.019
  292. Malheiros, J.M.; Braga, C.P.; Grove, R.A.; Ribeiro, F.A.; Calkins, C.R.; Adamec, J.; Chardulo, L.A.L. Influence of oxidative damage to proteins on meat tenderness using a proteomics approach. Meat Science, 2019, 148, 64–71. doi: 10.1016/j.meatsci.2018.08.016
  293. Singaraju, G.S.; Sagar, A.; Kumar, A.; Samuel, J.S.; Hazra, J.P.; Sannigrahi, M.K.; Yennamalli, R.M.; Ashish; Rakshit, S. Structural basis of the strong cell-cell junction formed by cadherin-23. The Febs Journal, 2019, 287(11), 2328-2347. doi: 10.1111/febs.15141
  294. Novoselova, M.V.; German, S.V.; Sindeeva, O.A.; Kulikov, O.A.; Minaeva, O.V.; Brodovskaya, E.P.; Ageev, V.P.; Zharkov, M.N.; Pyataev, N.A.; Sukhorukov, G.B.; Gorin, D.A. Submicron-Sized Nanocomposite Magnetic-Sensitive Carriers: Controllable Organ Distribution and Biological Effects. Polymers, 2019, 11(6), 1082. doi: 10.3390/polym11061082
  295. Zheng, F.; Luo, S.; Ouyang, Z.; Zhou, J.; Mo, H.; Schoonooghe, S.; Muyldermans, S.; De Baetselier, P.; Raes, G.; Wen, Y. NIRF-Molecular Imaging with Synovial Macrophages-Targeting Vsig4 Nanobody for Disease Monitoring in a Mouse Model of Arthritis. International Journal of Molecular Sciences, 2019, 20(13), 3347. doi: 10.3390/ijms20133347
  296. Novopashina, D.; Vorobyeva, M.; Nazarov, A.; Davydova, A.; Danilin, N.; Koroleva, L.; Matveev, A.; Bardasheva, A.; Tikunova, N.; Kupryushkin, M.; Pyshnyi, D.; Altman, S.; Venyaminova, A. Novel Peptide Conjugates of Modified Oligonucleotides for Inhibition of Bacterial RNase P. Frontiers in Pharmacology, 2019, 10, 813. doi: 10.3389/fphar.2019.00813
  297. Quyen, T.L.; Ngo, T.A.; Bang, D.D.; Madsen, M.; Wolff, A. Classification of Multiple DNA Dyes Based on Inhibition Effects on Real-Time Loop-Mediated Isothermal Amplification (LAMP): Prospect for Point of Care Setting. Frontiers in Microbiology, 2019, 10, 2234. doi: 10.3389/fmicb.2019.02234
  298. Han, W.; Xie, B.; Li, Y.; Shi, L.; Wan, J.; Chen, X.; Wang, H. Orally Deliverable Nanotherapeutics for the Synergistic Treatment of Colitis-Associated Colorectal Cancer. Theranostics, 2019, 9(24), 7458-7473. doi: 10.7150/thno.38081
  299. Meschaninova, M.I.; Novopashina, D.S.; Semikolenova, O.A.; Silnikov, V.N.; Venyaminova, A.G. Novel Convenient Approach to the Solid-Phase Synthesis of Oligonucleotide Conjugates. Molecules, 2019, 24(23), 4266. doi: 10.3390/molecules24234266
  300. Shamul, J.G.; Shah, S.R.; Kim, J.; Schiapparelli, P.; Vazquez-Ramos, C.A.; Lee, B.J.; Patel, K.K.; Shin, A.; Quinones-Hinojosa, A.; Green, J.J. Verteporfin-Loaded Anisotropic Poly(Beta-Amino Ester)-Based Micelles Demonstrate Brain Cancer-Selective Cytotoxicity and Enhanced Pharmacokinetics. International Journal of Nanomedicine, 2019, 14, 10047-10060. doi: 10.2147/IJN.S231167
  301. Jiang, W.; Fang, H.; Liu, F.; Zhou, X.; Zhao, H.; He, X.; Guo, D. PEG-coated and Gd-loaded fluorescent silica nanoparticles for targeted prostate cancer magnetic resonance imaging and fluorescence imaging. International Journal of Nanomedicine, 2019, 14, 5611-5622. doi: 10.2147/IJN.S207098

2018

  1. Ye, K.; Sinawang, P.D.; Yoong, A.T.I.; Marks, R.S. Photoinducible silane diazirine as an effective crosslinker in the construction of a chemiluminescent immunosensor targeting a model E. coli analyte. Sensors and Actuators B: Chemical, 2018, 256, 234–242. doi: 10.1016/j.snb.2017.10.058
  2. Norred, S.E.; Dabbs, R.M.; Chauhan, G.; Caveney, P.M.; Collier, C.P.; Abel, S.M.; Simpson, M.L. Synergistic interactions between confinement and macromolecular crowding spatially order transcription and translation in cell-free expression. bioRxiv, 2018, preprint. doi: 10.1101/445544
  3. Bond, M.J.; Bleiler, M.; Harrison, L.E.; Scocchera, E.W.; Nakanishi, M.; G-Dayanandan, N.; Keshipeddy, S.; Rosenberg, D.W.; Wright, D.L.; Giardina, C. Spindle assembly disruption and cancer cell apoptosis with a CLTC-binding compound. Molecular Cancer Research, 2018, 16(9), 1361–1372. doi: 10.1158/1541-7786.MCR-18-0178
  4. Doh, J.K.; White, J.D.; Zane, H.K.; Chang, Y.H.; López, C.S.; Enns, C.A.; Beatty, K.E. VIPER is a genetically encoded peptide tag for fluorescence and electron microscopy. Proceedings of the National Academy of Sciences of the United States of America, 2018, 115, 12961–12966. doi: 10.1073/pnas.1808626115
  5. Smith, W.J.; Wang, G.; Gaikwad, H.; Vu, V.P.; Groman, E.; Bourne, D.W.A.; Simberg, D. Accelerated Blood Clearance of Antibodies by Nanosized Click Antidotes. ACS Nano, 2018, 12(12), 12523–12532. doi: 10.1021/acsnano.8b07003
  6. Chen, G.; Ma, B.; Xie, R.; Wang, Y.; Dou, K.; Gong, S. NIR-induced spatiotemporally controlled gene silencing by upconversion nanoparticle-based siRNA nanocarrier. Journal of Controlled Release, 2018, 282, 148–155. doi: 10.1016/j.jconrel.2017.12.028
  7. Rink, W.M.; Thomas, F. Decoration of Coiled-Coil Peptides with N-Cysteine Peptide Thioesters As Cyclic Peptide Precursors Using Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC) Click Reaction. Organic Letters, 2018, 20(23), 7493–7497. doi: 10.1021/acs.orglett.8b03261
  8. Wang, Z.; Zhang, R.X.; Zhang, T.; He, C.; He, R.; Ju, X.; Wu, X.Y. In Situ Proapoptotic Peptide-Generating Rapeseed Protein-Based Nanocomplexes Synergize Chemotherapy for Cathepsin-B Overexpressing Breast Cancer. ACS Applied Materials & Interfaces, 2018, 10(48), 41056–41069. doi: 10.1021/acsami.8b14001
  9. Shi, M.; Chen, B.; Mahajan, D.; Boh, B.K.; Zhou, Y.; Dutta, B.; Tie, H.C.; Sze, S.K.; Wu, G.; Lu, L. Amino acids stimulate the endosome-to-Golgi trafficking through Ragulator and small GTPase Arl5. Nature Communications, 2018, 9, 4987. doi: 10.1038/s41467-018-07444-y
  10. Crupi, A.N.; Nunnelee, J.S.; Taylor, D.J.; Thomas, A.; Vit, J.-P.; Riera, C.E.; Gottlieb, R.A.; Goodridge, H.S. Oxidative muscles have better mitochondrial homeostasis than glycolytic muscles throughout life and maintain mitochondrial function during aging. Aging, 2018, 10(11), 3327–3352. doi: 10.18632/aging.101643
  11. Shih, F.-Y.; Su, I.-J.; Chu, L.-L.; Lin, X.; Kuo, S.-C.; Hou, Y.-C.; Chiang, Y.-T. Development of Pectin-Type B Gelatin Polyelectrolyte Complex for Curcumin Delivery in Anticancer Therapy. International Journal of Molecular Sciences, 2018, 19, E3625. doi: 10.3390/ijms19113625
  12. Li, Z.; Behrens, A.M.; Ginat, N.; Tzeng, S.Y.; Lu, X.; Sivan, S.; Langer, R.; Jaklenec, A. Biofilm-Inspired Encapsulation of Probiotics for the Treatment of Complex Infections. Advanced Materials, 2018, 30(51), e1803925. doi: 10.1002/adma.201803925
  13. Delasoie, J.; Rossier, J.; Haeni, L.; Rothen-Rutishauser, B.; Zobi, F. Slow-targeted release of a ruthenium anticancer agent from vitamin B12 functionalized marine diatom microalgae. Dalton Transactions, 2018, 47(48), 17221–17232. doi: 10.1039/c8dt02914h
  14. van Driessche, A; Kocere, A.; Everaert, H.; Nuhn, L.; van Herck, S.; Griffiths, G.; Fenaroli, F.; de Geest, B.G. pH-sensitive hydrazone-linked doxorubicin nanogels via polymeric activated ester scaffolds: synthesis, assembly, in vitro and in vivo evaluation in tumor bearing zebrafish. Chemistry of Materials, 2018, 30(23), 8587–8596. doi: 10.1021/acs.chemmater.8b03702
  15. Li, L.; Liu, Y.; Li, H.; Guo, X.; He, X.; Geng, S.; Zhao, H.; Peng, X.; Shi, D.; Xiong, B.; Zhou, G.; Zhao, Y.; Zheng, C.; Yang, X. Rational design of temperature-sensitive blood-vessel-embolic nanogels for improving hypoxic tumor microenvironment after transcatheter arterial embolization. Theranostics, 2018, 8(22), 6291–6306. doi: 10.7150/thno.28845
  16. Pawar, G.N.; Parayath, N.N.; Nocera, A.L.; Bleier, B.S.; Amiji, M.M. Direct CNS delivery of proteins using thermosensitive liposome-in-gel carrier by heterotopic mucosal engrafting. PLoS One, 2018, 13, e0208122. doi: 10.1371/journal.pone.0208122
  17. Domljanovic, I.; Hansen, A.H.; Hansen, L.H.; Klitgaard, J.K.; Taskova, M.; Astakhova, K. Studies of Impending Oligonucleotide Therapeutics in Simulated Biofluids. Nucleic Acid Therapeutics, 2018, 28(6), 348–356. doi: 10.1089/nat.2017.0704
  18. Komarova, N.; Andrianova, M.; Glukhov, S.; Kuznetsov, A. Selection, Characterization, and Application of {ssDNA} Aptamer against Furaneol. Molecules, 2018, 23(12), 3159. doi: 10.3390/molecules23123159
  19. Yu, C.; Tang, J.; Loredo, A.; Chen, Y.; Jung, S.Y.; Jain, A.; Gordon, A.; Xiao, H. Proximity-Induced Site-Specific Antibody Conjugation. Bioconjugate Chemistry, 2018, 29(11), 3522–3526. doi: 10.1021/acs.bioconjchem.8b00680
  20. Pitek, A.S.; Hu, H.; Shukla, S.; Steinmetz, N.F. Cancer Theranostic Applications of Albumin-Coated Tobacco Mosaic Virus Nanoparticles. ACS Applied Materials & Interfaces, 2018, 10(46), 39468–39477. doi: 10.1021/acsami.8b12499
  21. Liu, Y.; Li, Q.; Xiong, X.; Huang, Y.; Zhou, Z. Enhanced cellular uptake by non-endocytic pathway for tumor therapy. Journal of Materials Chemistry B, 2018, 6(45), 7411–7419. doi: 10.1039/c8tb01698d
  22. Meena, G.G.; Jain, A.; Parks, J.; Stambaugh, A.; Patterson, J.; Hawkins, A.; Schmidt, H. Integration of sample preparation and analysis on an optofluidic chip for multi-target disease detection. Lab on a Chip, 2018, 18(23), 3678–3686. doi: 10.1039/c8lc00966j
  23. Korzhikov-Vlakh, V.; Averianov, I.; Sinitsyna, E.; Nashchekina, Y.; Polyakov, D.; Guryanov, I.; Lavrentieva, A.; Raddatz, L.; Korzhikova-Vlakh, E.; Scheper, T.; Tennikova, T. Novel Pathway for Efficient Covalent Modification of Polyester Materials of Different Design to Prepare Biomimetic Surfaces. Polymers, 2018, 10(12), 1299. doi: 10.3390/polym10121299
  24. Ranjit, S.; Malacrida, L.; Gratton, E. Differences between FLIM phasor analyses for data collected with the Becker and Hickl SPC830 card and with the FLIMbox card. Microscopy Research and Technique, 2018, 81(9), 980–989. doi: 10.1002/jemt.23061
  25. Zahid, M.; Feldman, K.S.; Garcia-Borrero, G.; Feinstein, T.N.; Pogodzinski, N.; Xu, X.; Yurko, R.; Czachowski, M.; Wu, Y.L.; Mason, N.S.; Lo, C.W. Cardiac Targeting Peptide, a Novel Cardiac Vector: Studies in Bio-Distribution, Imaging Application, and Mechanism of Transduction. Biomolecules, 2018, 8(4), 147. doi: 10.3390/biom8040147
  26. Cui, X.-Y.; Sun, N.-N.; Xie, X.-N.; Sun, W.-C.; Zhao, Q.; Liu, N. Detection of Newly Synthesized Proteins via Metabolic Incorporation of Non-natural Amino Acid. Chinese Journal of Analytical Chemistry, 2018, 46(11), 1808–1813. doi: 10.1016/s1872-2040(18)61125-9
  27. Zhang, L.; Fang, Y.; Li, L.; Yang, J.; Radford, D.C.; Kopeček, J. Human Serum Albumin-Based Drug-Free Macromolecular Therapeutics: Apoptosis Induction by Coiled-Coil-Mediated Cross-Linking of CD20 Antigens on Lymphoma B Cell Surface. Macromolecular Bioscience, 2018, 18(11), e1800224. doi: 10.1002/mabi.201800224
  28. Shim, K.-S.; Kim, H.-J.; Kim, S.E.; Park, K. Simple surface biofunctionalization of biphasic calcium phosphates for improving osteogenic activity and bone tissue regeneration. Journal of Industrial and Engineering Chemistry, 2018, 68, 228–228. doi: 10.1016/j.jiec.2018.07.048
  29. Zhang, Q.; Scigliano, A.; Biver, T.; Pucci, A.; Swager, T.M. Interfacial Bioconjugation on Emulsion Droplet for Biosensors. Bioorganic & Medicinal Chemistry, 2018, 26(19), 5307–5313. doi: 10.1016/j.bmc.2018.04.020
  30. Ng, S.; Bennett, N.J.; Schulze, J.; Gao, N.; Rademacher, C.; Derda, R. Genetically-encoded Fragment-based Discovery of Glycopeptide Ligands for DC-SIGN. Bioorganic & Medicinal Chemistry, 2018, 26(19), 5368–5377. doi: 10.1016/j.bmc.2018.08.036
  31. Yang, J.; Xu, J.; Gonzalez, R.; Lindner, T.; Kratochwil, C.; Miao, Y. 68Ga-DOTA-GGNle-CycMSHhex targets the melanocortin-1 receptor for melanoma imaging. Science Translational Medicine, 2018, 10(466), eaau4445. doi: 10.1126/scitranslmed.aau4445
  32. Swenson, S.; Minea, R.O.; Tuan, C.D.; Thein, T.-Z.; Chen, T.C.; Markland, F.S. A Novel Venom-Derived Peptide for Brachytherapy of Glioblastoma: Preclinical Studies in Mice. Molecules, 2018, 23(11), 2918. doi: 10.3390/molecules23112918
  33. Swaminathan, J.; Boulgakov, A.A.; Hernandez, E.T.; Bardo, A.M.; Bachman, J.L.; Marotta, J.; Johnson, A.M.; Anslyn, E.V.; Marcotte, E.M. Highly parallel single-molecule identification of proteins in zeptomole-scale mixtures. Nature Biotechnology, 2018, 36(11), 1076–1082. doi: 10.1038/nbt.4278
  34. Alferova, V.A.; Shuvalov, M.V.; Suchkova, T.A.; Proskurin, G.V.; Aparin, I.O.; Rogozhin, E.A.; Novikov, R.A.; Solyev, P.N.; Chistov, A.A.; Ustinov, A.V.; Tyurin, A.P.; Korshun, V.A. 4-Chloro-L-kynurenine as fluorescent amino acid in natural peptides. Amino Acids, 2018, 50(12), 1697–1705. doi: 10.1007/s00726-018-2642-3
  35. Qiao, R.; Esser, L.; Fu, C.; Zhang, C.; Hu, J.; Ramírez-García, P.; Li, Y.; Quinn, J.F.; Whittaker, M.R.; Whittaker, A.K.; Davis, T.P. Bioconjugation and Fluorescence Labelling of Iron Oxide Nanoparticles Grafted with Bromomaleimide-terminal Polymers. Biomacromolecules, 2018, 19(11), 4423–4429. doi: 10.1021/acs.biomac.8b01282
  36. Nuhn, L.; De Koker, S.; Van Lint, S.; Zhong, Z.; Catani, J.P.; Combes, F.; Deswarte, K.; Li, Y.; Lambrecht, B.N.; Lienenklaus, S.; Sanders, N.N.; David, S.A.; Tavernier, J.; De Geest, B.G. Nanoparticle-Conjugate TLR7/8 Agonist Localized Immunotherapy Provokes Safe Antitumoral Responses. Advanced Materials, 2018, 30(45), e1803397. doi: 10.1002/adma.201803397
  37. Lee, S.Y.; Ko, S.-H.; Shim, J.-S.; Kim, D.-D.; Cho, H.-J. Tumor Targeting and Lipid Rafts Disrupting Hyaluronic Acid-Cyclodextrin-Based Nanoassembled Structure for Cancer Therapy. ACS Applied Materials & Interfaces, 2018, 10(43), 36628–36640. doi: 10.1021/acsami.8b08243
  38. Konopka, C.J.; Wozniak, M.; Hedhli, J.; Ploska, A.; Schwartz-Duval, A.; Siekierzycka, A.; Pan, D.; Munirathinam, G.; Dobrucki, I.T.; Kalinowski, L.; Dobrucki, L.W. Multimodal imaging of the receptor for advanced glycation end-products with molecularly targeted nanoparticles. Theranostics, 2018, 8(18), 5012–5024. doi: 10.7150/thno.24791
  39. van Herck, S.; Deswarte, K.; Nuhn, L.; Zhong, Z.; Portela Catani, J.P.; Li, Y.; Sanders, N.N.; Lienenklaus, S.; De Koker, S.; Lambrecht, B.N.; David, S.A.; De Geest, B.G. Lymph-Node-Targeted Immune Activation by Engineered Block Copolymer Amphiphiles-TLR7/8 Agonist Conjugates. Journal of the American Chemical Society, 2018, 140, 14300–14307. doi: 10.1021/jacs.8b08595
  40. Arevalo-Martin, A.; Grassner, L.; Garcia-Ovejero, D.; Paniagua-Torija, B.; Barroso-Garcia, G.; Arandilla, A.G.; Mach, O.; Turrero, A.; Vargas, E.; Alcobendas, M.; Rosell, C.; Alcaraz, M.A.; Ceruelo, S.; Casado, R.;Talavera, F.; Palazón, R.; Sanchez-Blanco, N.; Maier, D.; Esclarin, A.; Molina-Holgado, E. Elevated Autoantibodies in Subacute Human Spinal Cord Injury Are Naturally Occurring Antibodies. Frontiers in Immunology, 2018, 9, 2365. doi: 10.3389/fimmu.2018.02365
  41. Segal, E.S.; Gritsenko, V.; Levitan, A.; Yadav, B.; Dror, N.; Steenwyk, J.L.; Silberberg, Y.; Mielich, K.; Rokas, A.; Gow, N.A.R.; Kunze, R.; Sharan, R.; Berman, J. Gene Essentiality Analyzed by In Vivo Transposon Mutagenesis and Machine Learning in a Stable Haploid Isolate of Candida albicans. mBio, 2018, 9(5), e02048-18. doi: 10.1128/mBio.02048-18
  42. Hyun, J.Y.; Kim, S.; Lee, H.S.; Shin, I. A Glycoengineered Enzyme with Multiple Mannose-6-Phosphates Is Internalized into Diseased Cells to Restore Its Activity in Lysosomes. Cell Chemical Biology, 2018, 25(10), 1255–1267.e8. doi: 10.1016/j.chembiol.2018.07.011
  43. Ishihara, J.; Ishihara, A.; Potin, L.; Hosseinchi, P.; Fukunaga, K.; Damo, M.; Gajewski, T.F.; Swartz, M.A.; Hubbell, J.A. Improving Efficacy and Safety of Agonistic Anti-CD40 Antibody Through Extracellular Matrix Affinity. Molecular Cancer Therapeutics, 2018, 17(11), 2399–2411. doi: 10.1158/1535-7163.MCT-18-0091
  44. Joo, J.; Poon, C.; Yoo, S.P.; Chung, E.J. Shape Effects of Peptide Amphiphile Micelles for Targeting Monocytes. Molecules, 2018, 23(11), 2786. doi: 10.3390/molecules23112786
  45. Bellat, V.; Ting, R.; Southard, T.L.; Vahdat, L.; Molina, H.; Fernandez, J.; Aras, O.; Stokol, T.; Law, B. Functional Peptide Nanofibers with Unique Tumor Targeting and Enzyme-Induced Local Retention Properties. Advanced Functional Materials, 2018, 28(44), 1803969. doi: 10.1002/adfm.201803969
  46. Zhang, J.; Chetnani, B.; Cormack, E.D.; Alonso, D.; Liu, W.; Mondragon, A.; Fei, J. Specific structural elements of the T-box riboswitch drive the two-step binding of the tRNA ligand. eLife, 2018, 7, e39518. doi: 10.7554/eLife.39518
  47. Smith, J.D.; Cardwell, L.N.; Porciani, D.; Nguyen, J.A.; Gallazzi, F.; Tata, R.R.; Burke, D.H.; Daniels, M.A.; Ulery, B. Aptamer-displaying peptide amphiphile micelles as a cell-targeted delivery vehicle of peptide cargoes. Physical Biology, 2018, 15(6), 065006. doi: 10.1088/1478-3975/aadb68
  48. Stefaniak, J.; Lewis, A.M.; Conole, D.; Galan, S.R.G.; Bataille, C.J.R.; Wynne, G.M.; Castaldi, M.P.; Lundbäck, T.; Russell, A.J.; Huber, K.V.M. Chemical Instability and Promiscuity of Arylmethylidenepyrazolinone-Based MDMX Inhibitors. ACS Chemical Biology, 2018, 13(10), 2849–2854. doi: 10.1021/acschembio.8b00665
  49. Lee, K.; Yu, Y. Lipid Bilayer Disruption by Amphiphilic Janus Nanoparticles: The Role of Janus Balance. Langmuir, 2018, 34(41), 12387–12393. doi: 10.1021/acs.langmuir.8b02298
  50. Gurnani, Pratik and Sanchez-Cano, C.; Abraham, K.; Xandri-Monje, H.; Cook, A.B.; Hartlieb, M.; Lévi, F.; Dallmann, R.; Perrier, S. RAFT Emulsion Polymerization as a Platform to Generate Well-Defined Biocompatible Latex Nanoparticles. Macromolecular Bioscience, 2018, 18(10), e1800213. doi: 10.1002/mabi.201800213
  51. Wu, B.; Zhang, H.; Sun, R.; Peng, S.; Cooperman, B.S.; Goldman, Y.E.; Chen, C. Translocation kinetics and structural dynamics of ribosomes are modulated by the conformational plasticity of downstream pseudoknots. Nucleic Acids Research, 2018, 46(18), 9736–9748. doi: 10.1093/nar/gky636
  52. Khang, M.K.; Zhou, J.; Huang, Y.; Hakamivala, A.; Tang, L. Preparation of a novel injectable in situ-gelling nanoparticle with applications in controlled protein release and cancer cell entrapment. RSC Advances, 2018, 8(60), 34625–34633. doi: 10.1039/c8ra06589f
  53. Lufton, M.; Bustan, O.; Eylon, B.-h.; Shtifman-Segal, E.; Croitoru-Sadger, T.; Shagan, A.; Shabtay-Orbach, A.; Corem-Salkmon, E.; Berman, J.; Nyska, A.; Mizrahi, B. Living Bacteria in Thermoresponsive Gel for Treating Fungal Infections. Advanced Functional Materials, 2018, 28(40), 1801581. doi: 10.1002/adfm.201801581
  54. Li, W.; Li, Y.; Liu, Z.; Kerdsakundee, N.; Zhang, M.; Zhang, F.; Liu, X.; Bauleth-Ramos, T.; Lian, W.; Mäkilä, E.; Kemell, M.; Ding, Y.; Sarmento, B.; Wiwattanapatapee, R.; Salonen, J.; Zhang, H.; Hirvonen, J.T.; Liu, D.; Deng, X.; Santos, H.A. Hierarchical structured and programmed vehicles deliver drugs locally to inflamed sites of intestine. Biomaterials, 2018, 185, 322–332. doi: 10.1016/j.biomaterials.2018.09.024
  55. Besford, Q.A.; Ju, Y.; Wang, T.-Y.; Yun, G.; Cherepanov, P.V.; Hagemeyer, C.E.; Cavalieri, F.; Caruso, F. Self-Assembled Metal-Phenolic Networks on Emulsions as Low-Fouling and pH-Responsive Particles. Small, 2018, 14(39), e1802342. doi: 10.1002/smll.201802342
  56. Kumar, R.; Welle, A.; Becker, F.; Kopyeva, I.; Lahann, J. Substrate-Independent Micropatterning of Polymer Brushes Based on Photolytic Deactivation of Chemical Vapor Deposition Based Surface-Initiated Atom-Transfer Radical Polymerization Initiator Films. Applied Materials & Interfaces, 2018, 10(38), 31965–31976. doi: 10.1021/acsami.8b11525
  57. van Hall-Beauvais, A.; Zhao, Y.; Urul, D.A.; Long, M.J.C.; Aye, Y. Single-Protein-Specific Redox Targeting in Live Mammalian Cells and C. elegans. Current Protocols in Chemical Biology, 2018, 10(3), e43. doi: 10.1002/cpch.43
  58. Mickuté, M.; Nainyté, M.; Vasiliauskaité, L.; Plotnikova, A.; Masevičius, V.; Klimašauskas, S.; Vilkaitis, G. Animal Hen1 2'-O-methyltransferases as tools for 3'-terminal functionalization and labelling of single-stranded RNAs. Nucleic Acids Research, 2018, 46(17), e104. doi: 10.1093/nar/gky514
  59. Etrych, T.; Daumová, L.; Pokorná, E.; Tušková, D.; Lidický, O.; Kolářová, V.; Pankrác, J.; Šefc, L.; Chytil, P.; Klener, P. Effective doxorubicin-based nano-therapeutics for simultaneous malignant lymphoma treatment and lymphoma growth imaging. Journal of Controlled Release, 2018, 289, 44–55. doi: 10.1016/j.jconrel.2018.09.018
  60. Eelen, G.; Dubois, C.; Cantelmo, A.R.; Goveia, J.; Brüning, U.; DeRan, M.; Jarugumilli, G.; van Rijssel, J.; Saladino, G.; Comitani, F.; Zecchin, A.; Rocha, S.; Chen, R.; Huang, H.; Vandekeere, S.; Kalucka, J.; Lange, C.; Morales-Rodriguez, F.; Cruys, B.; Treps, L.; Ramer, L.; Vinckier, S.; Brepoels, K.; Wyns, S.; Souffreau, J.; Schoonjans, L.; Lamers, W.H.; Wu, Y.; Haustraete, J.; Hofkens, J.; Liekens, S.; Cubbon, R.; Ghesquière, B.; Dewerchin, M.; Gervasio, F.L.; Li, X.; van Buul, J.D.; Wu, X.; Carmeliet, P. Role of glutamine synthetase in angiogenesis beyond glutamine synthesis. Nature, 2018, 561(7721), 63–69. doi: 10.1038/s41586-018-0466-7
  61. Fu, Y.; Long, M.J.C.; Wisitpitthaya, S.; Inayat, H.; Pierpont, T.M.; Elsaid, I.M.; Bloom, J.C.; Ortega, J.; Weiss, R.S.; Aye, Y. Nuclear RNR-α antagonizes cell proliferation by directly inhibiting ZRANB3. Nature Chemical Biology, 2018, 14(10), 943–954. doi: 10.1038/s41589-018-0113-5
  62. Braselmann, E.; Wierzba, A.J.; Polaski, J.T.; Chromiński, M.; Holmes, Z.E.; Hung, S.-T.; Batan, D.; Wheeler, J.R.; Parker, R.; Jimenez, R.; Gryko, D.; Batey, R.T.; Palmer, A.E. A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells. Nature Chemical Biology, 2018, 14(10), 964–971. doi: 10.1038/s41589-018-0103-7
  63. Ta, D.T.; Vanella, R.; Nash, M.A. Bioorthogonal Elastin-like Polypeptide Scaffolds for Immunoassay Enhancement. ACS Applied Materials & Interfaces, 2018, 10(36), 30147–30154. doi: 10.1021/acsami.8b10092
  64. Xu, H.; Bandari, R.; Lee, L.E.; Li, R.; Yu, P.; Smith, C.J.; Ma, L. Design, Synthesis, and In Vitro and In Vivo Evaluation of High Affinity and Specificity Near-Infrared Fluorescent Bombesin Antagonists for Tumor Imaging. Journal of Medicinal Chemistry, 2018, 61(17), 7657–7670. doi: 10.1021/acs.jmedchem.8b00614
  65. Wang, Y.; Li, L.; Zhao, W.; Dou, Y.; An, H.; Tao, H.; Xu, X.; Jia, Y.; Lu, S.; Zhang, J.; Hu, H. Targeted Therapy of Atherosclerosis by a Broad-Spectrum Reactive Oxygen Species-Scavenging Nanoparticle with Intrinsic Anti-Inflammatory Activity. ACS Nano, 2018, 12(9), 8943–8960. doi: 10.1021/acsnano.8b02037
  66. Gomez, I.J.; Arnaiz, B.; Cacioppo, M.; Arcudi, F.; Prato, M. Nitrogen-doped Carbon Nanodots for bioimaging and delivery of paclitaxel. Journal of Materials Chemistry B, 2018, 6(35), 5540–5548. doi: 10.1039/c8tb01796d
  67. Zhang, C.; Moonshi, S.S.; Wang, W.; Ta, H.T.; Han, Y.; Han, F.Y.; Peng, H.; Král, P.; Rolfe, B.E.; Gooding, J.J.; Gaus, K.; Whittaker, A.K. High F-Content Perfluoropolyether-Based Nanoparticles for Targeted Detection of Breast Cancer by 19F Magnetic Resonance and Optical Imaging. ACS Nano, 2018, 12(9), 9162–9176. doi: 10.1021/acsnano.8b03726
  68. Pitek, A.S.; Park, J.; Wang, Y.; Gao, H.; Hu, H.; Simon, D.I.; Steinmetz, N.F. Delivery of thrombolytic therapy using rod-shaped plant viral nanoparticles decreases the risk of hemorrhage. Nanoscale, 2018, 10(35), 16547–16555. doi: 10.1039/c8nr02861c
  69. Zadeh, P.S.N.; do Valle Gomes, M.Z.; Abrahamsson, M.; Palmqvist, A.; Åkerman, B. Measuring Viscosity inside Mesoporous Silica Using Protein-Bound Molecular Rotor Probe. Physical Chemistry Chemical Physics, 2018, 20(36), 23202–23213. doi: 10.1039/C8CP01063C
  70. Spangler, B.; Dovala, D.; Sawyer, W.S.; Thompson, K.V.; Six, D.A.; Reck, F.; Feng, B.Y. Molecular probes for the determination of sub-cellular compound exposure profiles in Gram-negative bacteria. ACS Infectious Diseases, 2018, 4(9), 1355–1367. doi: 10.1021/acsinfecdis.8b00093
  71. Graham, T.G.W.; Carney, S.M.; Walter, J.C.; Loparo, J.J. A single XLF dimer bridges DNA ends during nonhomologous end joining. Nature Structural & Molecular Biology, 2018, 25(9), 877–884. doi: 10.1038/s41594-018-0120-y
  72. Zhao, Y.; Fletcher, N.L.; Liu, T.; Gemmell, A.C.; Houston, Z.H.; Blakey, I.; Thurecht, K.J. In vivo therapeutic evaluation of polymeric nanomedicines: effect of different targeting peptides on therapeutic efficacy against breast cancer. Nanotheranostics, 2018, 2(4), 360–370. doi: 10.7150/ntno.27142
  73. Karas, J.; Turner, B.J.; Shabanpoor, F. The Assembly of Fluorescently Labeled Peptide-Oligonucleotide Conjugates via Orthogonal Ligation Strategies. Methods in Molecular Biology, 2018, 1282, 355–363. doi: 10.1007/978-1-4939-8651-4_22
  74. Moon, C.H.; Lee, J.Y.; Kim, E.S.; Park, J.H.; Kim, S.-Y.; Kim, J.Y.; Tchah, H. In vivo biodistribution of topical low molecular weight heparin-taurocholate in a neovascularized mouse cornea. International Journal of Ophthalmology, 2018, 11(9), 1435–1439. doi: 10.18240/ijo.2018.09.01
  75. Zhang, Y.; Guo, Z.; Cao, Z.; Zhou, W.; Zhang, Y.; Chen, Q.; Lu, Y.; Chen, X.; Guo, Q.; Li, C.; Liang, D.; Sun, T.; Jiang, C. Endogenous albumin-mediated delivery of redox-responsive paclitaxel-loaded micelles for targeted cancer therapy. Biomaterials, 2018, 183, 243–257. doi: 10.1016/j.biomaterials.2018.06.002
  76. Moynihan, K.D.; Holden, R.L.; Mehta, N.K.; Wang, C.; Karver, M.R.; Dinter, J.; Liang, S.; Abraham, W.; Melo, M.B.; Zhang, A.Q.; Li, N.; Le Gall, S.; Pentelute, B.; Irvine, D.J. Enhancement of peptide vaccine immunogenicity by increasing lymphatic drainage and boosting serum stability. Cancer Immunology Research, 2018, 6(9), 1025–1038. doi: 10.1158/2326-6066.CIR-17-0607
  77. Babos, G.; Biró, E.; Meiczinger, M.; Feczkó, T. Dual Drug Delivery of Sorafenib and Doxorubicin from PLGA and PEG-PLGA Polymeric Nanoparticles. Polymers, 2018, 10(8), 895. doi: 10.3390/polym10080895
  78. Delcanale, P.; Miret-Ontiveros, B.; Arista-Romero, M.; Pujals, S.; Albertazzi, L. Nanoscale Mapping Functional Sites on Nanoparticles by Points Accumulation for Imaging in Nanoscale Topography (PAINT). ACS Nano, 2018, 12(8), 7629–7637. doi: 10.1021/acsnano.7b09063
  79. Henderson, L.; Neumann, O.; Kaffes, C.; Zhang, R.; Marangoni, V.; Ravoori, M.K.; Kundra, V.; Bankson, J.; Nordlander, P.; Halas, N.J. Routes to Potentially Safer T1 Magnetic Resonance Imaging Contrast in a Compact Plasmonic Nanoparticle with Enhanced Fluorescence. ACS Nano, 2018, 12(8), 8214–8223. doi: 10.1021/acsnano.8b03368
  80. Xu, C.; Wang, Y.; Yu, H.; Tian, H.; Chen, X. Multifunctional Theranostic Nanoparticles Derived from Fruit-Extracted Anthocyanins with Dynamic Disassembly and Elimination Abilities. ACS Nano, 2018, 12(8), 8255–8265. doi: 10.1021/acsnano.8b03525
  81. Melnychuk, N.; Klymchenko, A.S. DNA-Functionalized Dye-Loaded Polymeric Nanoparticles: Ultrabright FRET Platform for Amplified Detection of Nucleic Acids. Journal of the American Chemical Society, 2018, 140(34), 10856–10865. doi: 10.1021/jacs.8b05840
  82. Lomakin, Y.; Kudriaeva, A.; Kostin, N.; Terekhov, S.; Kaminskaya, A.; Chernov, A.; Zakharova, M.; Ivanova, M.; Simaniv, T.; Telegin, G.; Gabibov, A.; Belogurov, A. Diagnostics of autoimmune neurodegeneration using fluorescent probing. Scientific Reports, 2018, 8, 12679. doi: 10.1038/s41598-018-30938-0
  83. Tridgett, M.; Moore-Kelly, C.; Duprey, J.-L.H.A.; Iturbe, L.O.; Tsang, C.W.; Little, H.A.; Sandhu, S.K.; Hicks, M.R.; Dafforn, T.R.; Rodger, A. Linear dichroism of visible-region chromophores using M13 bacteriophage as an alignment scaffold. RSC Advances, 2018, 8(52), 29535–29543. doi: 10.1039/c8ra05475d
  84. Khor, S.Y.; Vu, M.N.; Pilkington, E.H.; Johnston, A.P.R.; Whittaker, M.R.; Quinn, J.F.; Truong, N.P.; Davis, T.P. Elucidating the Influences of Size, Surface Chemistry, and Dynamic Flow on Cellular Association of Nanoparticles Made by Polymerization-Induced Self-Assembly. Small, 2018, 14(34), e1801702. doi: 10.1002/smll.201801702
  85. Schrand, B.; Clark, E.; Levay, A.; Capote, A.R.; Martinez, O.; Brenneman, R.; Castro, I.; Gilboa, E. Hapten-mediated recruitment of polyclonal antibodies to tumors engenders antitumor immunity. Nature Communications, 2018, 9, 3348. doi: 10.1038/s41467-018-05566-x
  86. Razgoniaeva, N.; Rogers, S.; Moroz, P.; Cassidy, J.; Zamkov, M. Improving the spectral resolution in fluorescence microscopy through shaped-excitation imaging. Methods and Applications in Fluorescence, 2018, 6(4), 045006. doi: 10.1088/2050-6120/aad81c
  87. Lv, J.; He, B.; Yu, J.; Wang, Y.; Wang, C.; Zhang, S.; Wang, H.; Hu, J.; Zhang, Q.; Cheng, Y. Fluoropolymers for intracellular and in vivo protein delivery. Biomaterials, 2018, 182, 167–175. doi: 10.1016/j.biomaterials.2018.08.023
  88. Lin, P.-Y.; Chiu, Y.-L.; Huang, J.-H.; Chuang, E.-Y.; Mi, F.-L.; Lin, K.-J.; Juang, J.-H.; Sung, H.-W.; Leong, K.W. Oral Nonviral Gene Delivery for Chronic Protein Replacement Therapy. Advanced Science, 2018, 5(8), 1701079. doi: 10.1002/advs.201701079
  89. Jin, Y.N.; Schlueter, P.J.; Jurisch-Yaksi, N.; Lam, P.-Y.; Jin, S.; Hwang, W.Y.; Yeh, J.-R.J.; Yoshigi, M.; Ong, S.-E.; Schenone, M.; Hartigan, C.R.; Carr, S.A.; Peterson, R.T. Noncanonical translation via deadenylated 3' UTRs maintains primordial germ cells. Nature Chemical Biology, 2018, 14(9), 844–852. doi: 10.1038/s41589-018-0098-0
  90. Machová, D.; Koziolová, E.; Chytil, P.; Venclíková, K.; Etrych, T.; Janoušková, O. Nanotherapeutics with suitable properties for advanced anticancer therapy based on HPMA copolymer-bound ritonavir via pH-sensitive spacers. European Journal of Pharmaceutics and Biopharmaceutics, 2018, 131, 141–150. doi: 10.1016/j.ejpb.2018.07.023
  91. Joshi, B.P.; Hardie, J.; Mingroni, M.A.; Farkas, M.E. Surface-Modified Macrophages Facilitate Tracking of Breast Cancer-Immune Interactions. ACS Chemical Biology, 2018, 13(8), 2339–2346. doi: 10.1021/acschembio.8b00509
  92. Navarro, L.A.; French, D.L.; Zauscher, S. Synthesis of Modular Brush Polymer-Protein Hybrids using Diazotransfer and Copper Click Chemistry. Bioconjugate Chemistry, 2018, 29(8), 2594–2605. doi: 10.1021/acs.bioconjchem.8b00309
  93. Babič, A.; Vinet, L.; Chellakudam, V.; Janikowska, K.; Allémann, E.; Lange, N. Squalene-PEG-exendin as high-affinity constructs for pancreatic beta-cells. Bioconjugate Chemistry, 2018, 29(8), 2531–2540. doi: 10.1021/acs.bioconjchem.8b00186
  94. Luthman, A.S. Wide-Field fHSI with a Linescan SRDA. In: Spectrally Resolved Detector Arrays for Multiplexed Biomedical Fluorescence Imaging (Springer Thesis), 2018, 51–85. doi: 10.1007/978-3-319-98255-7_3
  95. Melgar-Asensio, I.; Kandela, I.; Aird, F.; Darjatmoko, S.R.; de Los Rios, C.; Sorenson, C.M.; Albert, D.M.; Sheibani, N.; Henkin, J. Extended Intravitreal Rabbit Eye Residence of Nanoparticles Conjugated With Cationic Arginine Peptides for Intraocular Drug Delivery: In Vivo Imaging. Investigative Ophthalmology & Visual Science, 2018, 59(10), 4071–4081. doi: 10.1167/iovs.18-24087
  96. Gu, R.; Oweida, T.; Yingling, Y.G.; Chilkoti, A.; Zauscher, S. Enzymatic synthesis of nucleobase-modified single-stranded DNA offers tunable resistance to nuclease degradation. Biomacromolecules, 2018, 19(8), 3525–3535. doi: 10.1021/acs.biomac.8b00816
  97. Meka, R.R.; Venkatesha, S.H.; Moudgil, K.D. Peptide-directed liposomal delivery improves the therapeutic index of an immunomodulatory cytokine in controlling autoimmune arthritis. Journal of Controlled Release, 2018, 286, 279–288. doi: 10.1016/j.jconrel.2018.08.007
  98. Santra, K.; Clark, K.D.; Maity, N.; Petrich, J.W.; Anderson, J.L. Exploiting Fluorescence Spectroscopy to Identify Magnetic Ionic Liquids Suitable for the Isolation of Oligonucleotides. The Journal of Physical Chemistry B, 2018, 122(31), 7747–7756. doi: 10.1021/acs.jpcb.8b05580
  99. Lu, Z.; Huang, F.-Y.; Cao, R.; Tan, G.-H.; Yi, G.; He, N.; Xu, L.; Zhang, L. Intrinsic, cancer cell-selective toxicity of organic photothermal nano-agent: a simple formulation for combined photothermal-chemotherapy of cancer. ACS Applied Materials & Interfaces, 2018, 10(31), 26028–26038. doi: 10.1021/acsami.8b07801
  100. Lu, J.; Tang, M.; Liu, Y.; Wang, J.; Wu, Z. Comparative Proteomics of Chromium-Transformed Beas-2B Cells by 2D-DIGE and MALDI-TOF/TOF MS. Biological Trace Element Research, 2018, 185(1), 78–88. doi: 10.1007/s12011-017-1222-9
  101. Kumar, P.; Kuhlmann, F.M.; Chakroborty, S.; Bourgeois, A.L.; Foulke-Abel, J.; Tumala, B.; Vickers, T.J.; Sack, D.A.; DeNearing, B.; Harro, C.D.; Wright, W.S.; Gildersleeve, J.C.; Ciorba, M.A.; Santhanam, S.; Porter, C.K.; Gutierrez, R.L.; Prouty, M.G.; Riddle, M.S.; Polino, A.; Sheikh, A.; Donowitz, M.; Fleckenstein, J.M. Enterotoxigenic Escherichia coli blood group A interactions intensify diarrheal severity. The Journal of Clinical Investigation, 2018, 128(8), 3298–3311. doi: 10.1172/JCI97659
  102. Pivovarov, V.D.; Ryazantsev, D.Y.; Simonova, M.A.; Yegorova, T.V.; Khlgatian, S.V.; Zavriev, S.K.; Svirshchevskaya, E.V. Immuno-PCR Assay for Quantitation of Antibodies to Epstein-Barr Virus. Molecular Biology, 2018, 52(4), 629–635. doi: 10.1134/S0026893318040155
  103. Barry, R.; John, S.W.; Liccardi, G.; Tenev, T.; Jaco, I.; Chen, C.-H.; Choi, J.; Kasperkiewicz, P.; Fernandes-Alnemri, T.; Alnemri, E.; Drag, M.; Chen, Y.; Meier, P. SUMO-mediated regulation of NLRP3 modulates inflammasome activity. Nature Communications, 2018, 9, 3001. doi: 10.1038/s41467-018-05321-2
  104. Li, W.; Zhou, Y.; Tang, G.; Wong, N.-K.; Yang, M.; Tan, D.; Xiao, Y. Chemoproteomics Reveals the Anti-proliferative Potential of Parkinson's Disease Kinase Inhibitor LRRK2-IN-1 by Targeting PCNA Protein. Molecular Pharmaceutics, 2018, 15(8), 3252–3259. doi: 10.1021/acs.molpharmaceut.8b00325
  105. Franke, C.E.; Czapar, A.E.; Patel, R.B.; Steinmetz, N.F. Tobacco Mosaic Virus-Delivered Cisplatin Restores Efficacy in Platinum-Resistant Ovarian Cancer Cells. Molecular Pharmaceutics, 2018, 15(8), 2922–2931. doi: 10.1021/acs.molpharmaceut.7b00466
  106. Zadeh, P.S.N.; do Valle Gomes, M.Z.; Åkerman, B.; Palmqvist, A.E.C. Förster resonance energy transfer study of the improved biocatalytic conversion of CO2 to formaldehyde by co-immobilization of enzymes in siliceous mesostructured cellular foams. ACS Catalysis, 2018, 8(8), 7251–7260. doi: 10.1021/acscatal.8b01806
  107. Jones, J.E.; Busi, S.B.; Mitchem, J.B.; Amos-Landgraf, J.M.; Lewis, M.R. Evaluation of a Tumor-Targeting, Near-Infrared Fluorescent Peptide for Early Detection and Endoscopic Resection of Polyps in a Rat Model of Colorectal Cancer. Molecular Imaging, 2018, 17, 1536012118790065. doi: 10.1177/1536012118790065
  108. Dutta, D.; Lai, K.-Y.; Reyes-Ordoñez, A.; Chen, J.; van der Donk, W.A. Lanthionine synthetase C-like protein 2 (LanCL2) is Important for Adipogenic Differentiation. Journal of Lipid Research, 2018, 59(8), 1433–1445. doi: 10.1194/jlr.M085274
  109. Nuhn, L.; Van Hoecke, L.; Deswarte, K.; Schepens, B.; Li, Y.; Lambrecht, B.N.; De Koker, S.; David, S.A.; Saelens, X.; De Geest, B.G. Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist. Biomaterials, 2018, 178, 643–651. doi: 10.1016/j.biomaterials.2018.03.026
  110. Liu, G.W.; Prossnitz, A.N.; Eng, D.G.; Cheng, Y.; Subrahmanyam, N.; Pippin, J.W.; Lamm, R.J.; Ngambenjawong, C.; Ghandehari, H.; Shankland, S.J.; Pun, S.H. Glomerular disease augments kidney accumulation of synthetic anionic polymers. Biomaterials, 2018, 178, 317–325. doi: 10.1016/j.biomaterials.2018.06.001
  111. Shvadchak, V.; Zgheib, S.; Basta, B.; Humbert, N.; Langedijk, J.; Morris, M.C.; Ciaco, S.; Maskri, O.; Darlix, J.-L.; Mauffret, O.; Fossé, P.; Réal, E.; Mély, Y. Rationally Designed Peptides as Efficient Inhibitors of Nucleic Acid Chaperone Activity of HIV-1 Nucleocapsid Protein. Biochemistry, 2018, 57(30), 4562–4573. doi: 10.1021/acs.biochem.8b00527
  112. Kongkatigumjorn, N.; Smith, S.A.; Chen, M.Z.; Fang, K.; Yang, S.; Gillies, E.R.; Johnston, A.P.R.; Such, G.K. Controlling Endosomal Escape Using pH Responsive Nanoparticles with Tunable Disassembly. Applied Nano Materials, 2018, 1(7), 3164–3173. doi: 10.1021/acsanm.8b00338
  113. Ruan, S.; Qin, L.; Xiao, W.; Hu, C.; Zhou, Y.; Wang, R.; Sun, X.; Yu, W.; He, Q.; Gao, H. Acid-Responsive Transferrin Dissociation and GLUT Mediated Exocytosis for Increased Blood-Brain Barrier Transcytosis and Programmed Glioma Targeting Delivery. Advanced Functional Materials, 2018, 28(30), 1802227. doi: 10.1002/adfm.201802227
  114. He, S.; Li, C.; Zhang, Q.; Ding, J.; Liang, X.-J.; Chen, X.; Xiao, H.; Chen, X.; Zhou, D.; Huang, Y. Tailoring Platinum(IV) Amphiphiles for Self-Targeting All-in-One Assemblies as Precise Multimodal Theranostic Nanomedicine. ACS Nano, 2018, 12(7), 7272–7281. doi: 10.1021/acsnano.8b03476
  115. Wu, C.; Li, J.; Wang, W.; Hammond, P.T. Rationally Designed Polycationic Carriers for Potent Polymeric siRNA-Mediated Gene Silencing. ACS Nano, 2018, 12(7), 6504–6514. doi: 10.1021/acsnano.7b08777
  116. Bonnard, T.; Jayapadman, A.; Putri, J.A.; Cui, J.; Ju, Y.; Carmichael, C.; Angelovich, T.A.; Cody, S.H.; French, S.; Pascaud, K.; Pearce, H.A.; Jagdale, S.; Caruso, F.; Hagemeyer, C.E. Low-Fouling and Biodegradable Protein-Based Particles for Thrombus Imaging. ACS Nano, 2018, 12(7), 6988–6996. doi: 10.1021/acsnano.8b02588
  117. Surya, S.L.; Long, M.J.C.; Urul, D.A.; Zhao, Y.; Mercer, E.J.; EIsaid, I.M.; Evans, T.; Aye, Y. Cardiovascular Small Heat Shock Protein HSPB7 Is a Kinetically Privileged Reactive Electrophilic Species (RES) Sensor. ACS Chemical Biology, 2018, 13(7), 1824–1831. doi: 10.1021/acschembio.7b00925
  118. Owiti, N.; Wei, S.; Bhagwat, A.; Kim, N. Unscheduled DNA synthesis leads to elevated uracil residues at highly transcribed genomic loci in Saccharomyces cerevisiae. PLoS Genetics, 2018, 14(7), e1007516. doi: 10.1371/journal.pgen.1007516
  119. Guo, X.; Zou, C.-L.; Jung, H.; Gong, Z.; Bruch, A.; Jiang, L.; Tang, H.X. Efficient Generation of a Near-visible Frequency Comb via Cherenkov-like Radiation from a Kerr Microcomb. Physical Review Applied, 2018, 10(1), 014012. doi: 10.1103/PhysRevApplied.10.014012
  120. Stambaugh, A.; Parks, J.W.; Stott, M.A.; Meena, G.G.; Hawkins, A.R.; Schmidt, H. Optofluidic detection of Zika nucleic acid and protein biomarkers using multimode interference multiplexing. Biomedical Optics Express, 2018, 9(8), 3725–3730. doi: 10.1364/BOE.9.003725
  121. Deshmukh, R.; Biehs, S.-A.; Khwaja, E.; Galfsky, T.; Agarwal, G.S.; Menon, V.M. Long-range resonant energy transfer using optical topological transitions in metamaterials. ACS Photonics, 2018, 5(7), 2737–2741. doi: 10.1021/acsphotonics.8b00484
  122. Yang, J.; Jiang, Q.; He, L.; Zhan, P.; Liu, Q.; Liu, S.; Fu, M.; Liu, J.; Li, C.; Ding, B. Self-Assembled Double-Bundle DNA Tetrahedron for Efficient Antisense Delivery. ACS Applied Materials & Interfaces, 2018, 10(28), 23693–23699. doi: 10.1021/acsami.8b07889
  123. Nuhn, L.; Boli, E.; Massa, S.; Vandenberghe, I.; Movahedi, K.; Devreese, B.; Van Ginderachter, J.; De Geest, B.G. Targeting protumoral tumor-associated macrophages with nanobody-functionalized nanogels through SPAAC ligation. Bioconjugate Chemistry, 2018, 29(7), 2394–2405. doi: 10.1021/acs.bioconjchem.8b00319
  124. Men, Y.; Peng, S.; Yang, P.; Jiang, Q.; Zhang, Y.; Shen, B.; Dong, P.; Pang, Z.; Yang, W. Biodegradable Zwitterionic Nanogels with Long Circulation for Antitumor Drug Delivery. ACS Applied Materials & Interfaces, 2018, 10(28), 23509–23521. doi: 10.1021/acsami.8b03943
  125. Chung, S.W.; Choi, J.U.; Cho, Y.S.; Kim, H.R.; Won, T.H.; Dimitrion, P.; Jeon, O.-C.; Kim, S.W.; Kim, I.-S.; Kim, S.Y.; Byun, Y. Self-Triggered Apoptosis Enzyme Prodrug Therapy (STAEPT): Enhancing Targeted Therapies via Recurrent Bystander Killing Effect by Exploiting Caspase-Cleavable Linker. Advanced Science, 2018, 5(7), 1800368. doi: 10.1002/advs.201800368
  126. Hernandez-Segura, A.; Brandenburg, S.; Demaria, M. Induction and Validation of Cellular Senescence in Primary Human Cells. Journal of Visualized Experiments, 2018, 136, e57782. doi: 10.3791/57782
  127. Tabe, H.; Sukenobe, K.; Kondo, T.; Sakurai, A.; Maruo, M.; Shimauchi, A.; Hirano, M.; Uno, S.-N.; Kamiya, M.; Urano, Y.; Matsushita, M.; Fujiyoshi, S. Cryogenic Fluorescence Localization Microscopy of Spectrally Selected Individual FRET Pairs in a Water Matrix. The Journal of Physical Chemistry B, 2018, 122(27), 6906–6911. doi: 10.1021/acs.jpcb.8b03977
  128. Tamošiūnė, I.; Stanienė, G.; Haimi, P.; Stanys, V.; Rugienius, R.; Baniulis, D. Endophytic Bacillus and Pseudomonas spp. Modulate Apple Shoot Growth, Cellular Redox Balance, and Protein Expression Under in Vitro Conditions. Frontiers in Plant Science, 2018, 9, 889. doi: 10.3389/fpls.2018.00889
  129. Salinas, C.B.G.; Lu, T.T.-H.; Gabery, S.; Marstal, K.; Alanentalo, T.; Mercer, A.J.; Cornea, A.; Conradsen, K.; Hecksher-Sørensen, J.; Dahl, A.B.; Knudsen, L.B.; Secher, A. Integrated Brain Atlas for Unbiased Mapping of Nervous System Effects Following Liraglutide Treatment. Scientific Reports, 2018, 8, 10310. doi: 10.1038/s41598-018-28496-6
  130. Souchek, J.J.; Wojtynek, N.E.; Payne, W.M.; Holmes, M.B.; Dutta, S.; Qi, B.; Datta, K.; LaGrange, C.A.; Mohs, A.M. Hyaluronic acid formulation of near infrared fluorophores optimizes surgical imaging in a prostate tumor xenograft. Acta Biomaterialia, 2018, 75, 323–333. doi: 10.1016/j.actbio.2018.06.016
  131. Nunes, R.; Araújo, F.; Tavares, J.; Sarmento, B.; das Neves, J. Surface modification with polyethylene glycol enhances colorectal distribution and retention of nanoparticles. European Journal of Pharmaceutics and Biopharmaceutics, 2018, 130, 200–206. doi: 10.1016/j.ejpb.2018.06.029
  132. Liu, H.-J.; Luan, X.; Feng, H.-Y.; Dong, X.; Yang, S.-C.; Chen, Z.-J.; Cai, Q.-Y.; Lu, Q.; Zhang, Y.; Sun, P.; Zhao, M.; Chen, H.-Z.; Lovell, J.F.; Fang, C. Integrated Combination Treatment Using a "Smart" Chemotherapy and MicroRNA Delivery System Improves Outcomes in an Orthotopic Colorectal Cancer Mode. Advanced Functional Materials, 2018, 28(28), 1801118. doi: 10.1002/adfm.201801118
  133. Tang, H.; Zhang, J.; Tang, J.; Shen, Y.; Guo, W.; Zhou, M.; Wang, R.; Jiang, N.; Gan, Z.; Yu, Q. Tumor specific and renal excretable star-like tri-block polymer-doxorubicin conjugates for safe and efficient anticancer therapy. Biomacromolecules, 2018, 19(7), 2849–2862. doi: 10.1021/acs.biomac.8b00425
  134. Sarker, B.; Walter, C.; Pathak, A. Direct micropatterning of {ECM} proteins on functionalized polyacrylamide hydrogels shows geometric regulation of cell-cell junctions. ACS Biomaterials Science & Engineering, 2018, 4(7), 2340–2349. doi: 10.1021/acsbiomaterials.8b00331
  135. Cui, Z.; Wu, Y.; Mureev, S.; Alexandrov, K. Oligonucleotide-mediated tRNA sequestration enables one-pot sense codon reassignment in vitro. Nucleic Acids Research, 2018, 46(12), 6387–6400. doi: 10.1093/nar/gky365
  136. Xue, F.; Wang, Y.; Zhang, Q.; Han, S.; Zhang, F.; Jin, T.; Li, C.; Hu, H.; Zhang, J. Self-assembly of affinity-controlled nanoparticles via host-guest interactions for drug delivery. Nanoscale, 2018, 10(26), 12364–12377. doi: 10.1039/C8NR01518J
  137. Tovar-Herrera, O.E.; Rodríguez, M.; Olarte-Lozano, M.; Sampedro-Guerrero, J.A.; Guerrero, A.; Pinto-Cámara, R.; Alvarado-Affantranger, X.; Wood, C.D.; Moran-Mirabal, J.M.; Pastor, N.; Segovia, L.; Martínez-Anaya, C. Analysis of the Binding of Expansin Exl1, from Pectobacterium carotovorum, to Plant Xylem and Comparison to EXLX1 from Bacillus subtilis. ACS Omega, 2018, 3(6), 7008–7018. doi: 10.1021/acsomega.8b00406
  138. Buecheler, J.W.; Winzer, M.; Tonillo, J.; Weber, C.A.; Gieseler, H. Impact of Payload Hydrophobicity on Stability of Antibody-Drug-Conjugates. Molecular Pharmaceutics, 2018, 15(7), 2656–2664. doi: 10.1021/acs.molpharmaceut.8b00177
  139. Chen, J.; Zhou, J.; Gao, Z.; Li, X.; Wang, F.; Duan, X.; Li, G.; Joshi, B.; Kuick, R.D.; Appelman, H.D.; Wang, T. Multiplexed Targeting of Barrett's Neoplasia with a Heterobivalent Ligand: Imaging Study on Mouse Xenograft In Vivo and Human Specimens Ex Vivo. Journal of Medicinal Chemistry, 2018, 61(12), 5323–5331. doi: 10.1021/acs.jmedchem.8b00405
  140. Wang, B.; Chen, G.; Urabe, G.; Xie, R.; Wang, Y.; Shi, X.; Guo, L.-W.; Gong, S.; Kent, K.C. A paradigm of endothelium-protective and stent-free anti-restenotic therapy using biomimetic nanoclusters. Biomaterials, 2018, 178, 293–301. doi: 10.1016/j.biomaterials.2018.06.025
  141. Roberts, S.; Andreou, C.; Choi, C.; Donabedian, P.; Jayaraman, M.; Pratt, E.C.; Tang, J.; Pérez-Medina, C.; de la Cruz, M.J.; Mulder, W.J.M.; Grimm, J.; Kircher, M.; Reiner, T. Sonophore-enhanced nanoemulsions for optoacoustic imaging of cancer. Chemical Science, 2018, 9(25), 5646–5657. doi: 10.1039/C8SC01706A
  142. Moroz, P.; Jin, Z.; Sugiyama, Y.; Lara, D'A.; Razgoniaeva, N.; Yang, M.; Kholmicheva, N.; Khon, D.; Mattoussi, H.; Zamkov, M. The Competition of Charge and Energy Transfer Processes in Donor-Acceptor Fluorescence Pairs: Calibrating the Spectroscopic Ruler. ACS Nano, 2018, 12(6), 5657–5665. doi: 10.1021/acsnano.8b01451
  143. Patiño, T.; Feiner-Gracia, N.; Arqué, X.; Miguel-López, A.; Jannasch, A.; Stumpp, T.; Schäffer, E.; Albertazzi, L.; Sánchez, S. Influence of Enzyme Quantity and Distribution on the Self-Propulsion of Non-Janus Urease-Powered Micromotors. Journal of the American Chemical Society, 2018, 140(25), 7896–7903. doi: 10.1021/jacs.8b03460
  144. Blackman, L.D.; Varlas, S.; Arno, M.C.; Houston, Z.H.; Fletcher, N.L.; Thurecht, K.J.; Hasan, M.; Gibson, M.I.; O'Reilly, R.K. Confinement of Therapeutic Enzymes in Selectively Permeable Polymer Vesicles by Polymerization-Induced Self-Assembly (PISA) Reduces Antibody Binding and Proteolytic Susceptibility. Central Science, 2018, 4(6), 718–723. doi: 10.1021/acscentsci.8b00168
  145. Garcia, F.; Rippe, M.; Companhoni, M.V.; Stefanello, T.; Louage, B.; van Herck, S.; Sancey, L.; Coll, J.-L.; De Geest, B.; Nakamura, C.V.; Auzély-Velty, R. A versatile method for the selective core-crosslinking of hyaluronic acid-based nanogels via ketone-hydrazide chemistry: from chemical characterization to in vivo biodistribution. Biomaterials Science, 2018, 6(7), 1754–1763. doi: 10.1039/c8bm00396c
  146. Selnihhin, D.; Sparvath, S.M.; Preus, S.; Birkedal, V.; Andersen, E.S. Multi-Fluorophore DNA Origami Beacon as a Biosensing Platform. ACS Nano, 2018, 12(6), 5699–5708. doi: 10.1021/acsnano.8b01510
  147. Li, H.; Li, K.; Dai, Y.; Xu, X.; Cao, X.; Zeng, Q.; He, H.; Pang, L.; Liang, J.; Chen, X.; Zhan, Y. In vivo near infrared fluorescence imaging and dynamic quantification of pancreatic metastatic tumors using folic acid conjugated biodegradable mesoporous silica nanoparticles. Nanomedicine: Nanotechnology, Biology and Medicine, 2018, 14(6), 1867–1877. doi: 10.1016/j.nano.2018.04.018
  148. Liang, Y.; Huo, Q.; Lu, W.; Jiang, L.; Gao, W.; Xu, L.; Han, S.; Cao, J.; Zhang, T.; Sun, Y.; He, B. Fluorescence Resonance Energy Transfer Visualization of Molecular Delivery from Polymeric Micelles. Journal of Biomedical Nanotechnology, 2018, 14(7), 1308–1316. doi: 10.1166/jbn.2018.2585
  149. Yang, Y.; Chen, Q.; Li, S.; Ma, W.; Yao, G.; Ren, F.; Cai, Z.; Zhao, P.; Liao, G.; Xiong, J.; Yu, Z. iRGD-Mediated and Enzyme-Induced Precise Targeting and Retention of Gold Nanoparticles for the Enhanced Imaging and Treatment of Breast Cancer. Journal of Biomedical Nanotechnology, 2018, 14(8), 1396–1408. doi: 10.1166/jbn.2018.2592
  150. Gusliakova, O.; Atochina-Vasserman, E.N.; Sindeeva, O.; Sindeev, S.; Pinyaev, S.; Pyataev, N.; Revin, V.; Sukhorukov, G.B.; Gorin, D.; Gow, A.J. Use of Submicron Vaterite Particles Serves as an Effective Delivery Vehicle to the Respiratory Portion of the Lung. Frontiers in Pharmacology, 2018, 9, 559. doi: 10.3389/fphar.2018.00559
  151. Chambre, L.; Degirmenci, A.; Sanyal, R.; Sanyal, A. Multifunctional Nanogels as Theranostic Platforms: Exploiting Reversible and Non-reversible Linkages for Targeting, Imaging and Drug Delivery. Bioconjugate Chemistry, 2018, 29(6), 1885–1896. doi: 10.1021/acs.bioconjchem.8b00085
  152. Ashwanikumar, N.; Plaut, J.S.; Mostofian, B.; Patel, S.; Kwak, P.; Sun, C.; McPhail, K.; Zuckerman, D.M.; Esener, S.C.; Sahay, G. Supramolecular self assembly of nanodrill-like structures for intracellular delivery. Journal of Controlled Release, 2018, 282, 76–89. doi: 10.1016/j.jconrel.2018.02.041
  153. Li, H.; Zhang, Z.; Bao, X.; Xu, G.; Yao, P. Fatty acid and quaternary ammonium modified chitosan nanoparticles for insulin delivery. Colloids and Surfaces, B: Biointerfaces, 2018, 170, 136–143. doi: 10.1016/j.colsurfb.2018.05.063
  154. Tsikandelova, R.; Mladenov, P.; Planchon, S.; Kalenderova, S.; Praskova, M.; Mihaylova, Z.; Stanimirov, P.; Mitev, V.; Renaut, J.; Ishkitiev, N. Proteome response of dental pulp cells to exogenous FGF8. Journal of Proteomics, 2018, 183, 14–24. doi: 10.1016/j.jprot.2018.05.004
  155. Parayath, N.N.; Parikh, A.; Amiji, M.M. Repolarization of Tumor-Associated Macrophages in a Genetically Engineered Nonsmall Cell Lung Cancer Model by Intraperitoneal Administration of Hyaluronic Acid-Based Nanoparticles Encapsulating MicroRNA-125b. Nano Letters, 2018, 18(6), 3571–3579. doi: 10.1021/acs.nanolett.8b00689
  156. Rho, J.Y.; Brendel, J.C.; MacFarlane, L.R.; Mansfield, E.D.H.; Peltier, R.; Rogers, S.; Hartlieb, M.; Perrier, S. Probing the Dynamic Nature of Self-Assembling Cyclic Peptide–Polymer Nanotubes in Solution and in Mammalian Cells. Advanced Functional Materials, 2018, 28(24), 1704569. doi: 10.1002/adfm.201704569
  157. Chiang, Y.-T.; Lyu, S.-Y.; Wen, Y.-H.; Lo, C.-L. Preparation and Characterization of Electrostatically Crosslinked Polymer-Liposomes in Anticancer Therapy. International Journal of Molecular Sciences, 2018, 19(6), 1615. doi: 10.3390/ijms19061615
  158. Hu, H.; Wan, J.; Huang, X.; Tang, Y.; Xiao, C.; Xu, H.; Yang, X.; Li, Z. iRGD-decorated reduction-responsive nanoclusters for targeted drug delivery. Nanoscale, 2018, 10(22), 10514–10527. doi: 10.1039/c8nr02534g
  159. Liu, C.-H.; Nevozhay, D.; Schill, A.; Singh, M.; Das, S.; Nair, A.; Han, Z.; Aglyamov, S.; Larin, K.V.; Sokolov, K.V. Nanobomb optical coherence elastography. Optics Letters, 2018, 43(9), 2006–2009. doi: 10.1364/OL.43.002006
  160. Malhotra, M.; Sekar, T.V.; Ananta, J.S.; Devulapally, R.; Afjei, R.; Babikir, H.A.; Paulmurugan, R.; Massoud, T.F. Targeted nanoparticle delivery of therapeutic antisense microRNAs presensitizes glioblastoma cells to lower effective doses of temozolomide in vitro and in a mouse model. Oncotarget, 2018, 9(30), 21478–21494. doi: 10.18632/oncotarget.25135
  161. Siltanen, C.A.; Cole, R.H.; Poust, S.; Chao, L.; Tyerman, J.; Kaufmann-Malaga, B.; Ubersax, J.; Gartner, Z.J.; Abate, A.R. An Oil-Free Picodrop Bioassay Platform for Synthetic Biology. Scientific Reports, 2018, 8, 7913. doi: 10.1038/s41598-018-25577-4
  162. Porciani, D.; Cardwell, L.N.; Tawiah, K.d.; Alam, K.K.; Lange, M.J.; Daniels, M.A.; Burke, D.H. Modular cell-internalizing aptamer nanostructure enables targeted delivery of large functional RNAs in cancer cell lines. Nature Communications, 2018, 9(1), 2283. doi: 10.1038/s41467-018-04691-x
  163. Ganapathy, U.S.; Bai, L.; Wei, L.; Eckartt, K.A.; Lett, C.M.; Previti, M.L.; Carrico, I.S.; Seeliger, J.C. Compartment-Specific Labeling of Bacterial Periplasmic Proteins by Peroxidase-Mediated Biotinylation. ACS Infectious Diseases, 2018, 4(6), 918–925. doi: 10.1021/acsinfecdis.8b00044
  164. Balke, J.; Volz, P.; Neumann, F.; Brodwolf, R.; Wolf, A.; Pischon, H.; Radbruch, M.; Mundhenk, L.; Gruber, A.D.; Ma, N.; Alexiev, U. Visualizing Oxidative Cellular Stress Induced by Nanoparticles in the Subcytotoxic Range Using Fluorescence Lifetime Imaging. Small, 2018, 14(23), 1800310. doi: 10.1002/smll.201800310
  165. Zemella, A.; Thoring, L.; Hoffmeister, C.; Šamalíková, M.; Ehren, P.; Wüstenhagen, D.A.; Kubick, S. Cell-free protein synthesis as a novel tool for directed glycoengineering of active erythropoietin. Scientific Reports, 2018, 8, 8514. doi: 10.1038/s41598-018-26936-x
  166. Tahara, H.; Takabe, K.; Sasaki, Y.; Kasuga, K.; Kawamoto, A.; Koizumi, N.; Nakamura, S. The mechanism of two-phase motility in the spirochete Leptospira: Swimming and crawling. Science Advances, 2018, 4(5), eaar7975. doi: 10.1126/sciadv.aar7975
  167. Semkina, A.S.; Abakumov, M.A.; Skorikov, A.S.; Abakumova, T.O.; Melnikov, P.A.; Grinenko, N.F.; Cherepanov, S.A.; Vishnevskiy, D.A.; Naumenko, V.A.; Ionova, K.P.; Majouga, A.G.; Chekhonin, V.P. Multimodal doxorubicin loaded magnetic nanoparticles for {VEGF} targeted theranostics of breast cancer. Nanomedicine: Nanotechnology, Biology and Medicine, 2018, 14(5), 1733–1742. doi: 10.1016/j.nano.2018.04.019
  168. Cun, X.; Li, M.; Wang, S.; Wang, Y.; Wang, J.; Lu, Z.; Yang, R.; Tang, X.; Zhang, Z.; He, Q. A size switchable nanoplatform for targeting the tumor microenvironment and deep tumor penetration. Nanoscale, 2018, 10(21), 9935–9948. doi: 10.1039/c8nr00640g
  169. Kao, C.-W.; Wu, P.-T.; Liao, M.-Y.; Chung, I.-J.; Yang, K.-C.; Tseng, W.-Y.I. Yu, J. Magnetic Nanoparticles Conjugated with Peptides Derived from Monocyte Chemoattractant Protein-1 as a Tool for Targeting Atherosclerosis. Pharmaceutics, 2018, 10(2), 62. doi: 10.3390/pharmaceutics10020062
  170. Shi, F.; Li, M.; Wang, J.; Wu, D.; Pan, M.; Guo, M.; Dou, J. Induction of multiple myeloma cancer stem cell apoptosis using conjugated anti-ABCG2 antibody with epirubicin-loaded microbubbles. Stem Cell Research & Therapy, 2018, 9, 144. doi: 10.1186/s13287-018-0885-2
  171. Shih, T.-Y.; Blacklow, S.O.; Li, A.W.; Freedman, B.R.; Bencherif, S.; Koshy, S.T.; Darnell, M.C.; Mooney, D.J. Injectable, Tough Alginate Cryogels as Cancer Vaccines. Advanced Healthcare Materials, 2018, 7(10), 1701469. doi: 10.1002/adhm.201701469
  172. Robinson, K.J.; Huynh, G.T.; Kouskousis, B.; Fletcher, N.L.; Houston, Z.H.; Thurecht, K.J.; Corrie, S.R. Modified organosilica core-shell nanoparticles for stable pH sensing in biological solutions. ACS Sensors, 2018, 3(5), 967–975. doi: 10.1021/acssensors.8b00034
  173. Mardirossian, M.; Pérébaskine, N.; Benincasa, M.; Gambato, S.; Hofmann, S.; Huter, P.; Müller, C.; Hilpert, K.; Innis, C.A.; Tossi, A.; Wilson, D.N. The Dolphin Proline-Rich Antimicrobial Peptide Tur1A Inhibits Protein Synthesis by Targeting the Bacterial Ribosome. Cell Chemical Biology, 2018, 25(5), 530–539.e7. doi: 10.1016/j.chembiol.2018.02.004
  174. Volkov, I.L.; Lindén, M.; Aguirre Rivera, J.; Ieong, K.-W.; Metelev, M.; Elf, J.; Johansson, M. tRNA tracking for direct measurements of protein synthesis kinetics in live cells. Nature Chemical Biology, 2018, 14(6), 618–626. doi: 10.1038/s41589-018-0063-y
  175. Akentieva, N.P.; Shushanov, S.S. Visualization of Ovarian Cancer Cells with Peptide VEGEGEEGEEY. Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology, 2018, 12(2), 189–198. doi: 10.1134/s1990747818020022
  176. Torres, O.B.; Duval, A.J.; Sulima, A.; Antoline, J.F.G.; Jacobson, A.E.; Rice, K.C.; Alving, C.R.; Matyas, G.R. A rapid solution-based method for determining the affinity of heroin hapten-induced antibodies to heroin, its metabolites, and other opioids. Analytical and Bioanalytical Chemistry, 2018, 410(16), 3885–3903. doi: 10.1007/s00216-018-1060-4
  177. Chen, C.C.; Stark, M.; Baikoghli, M.; Cheng, R.H. Surface Functionalization of Hepatitis E Virus Nanoparticles Using Chemical Conjugation Methods. Journal of Visualized Experiments, 2018, 135, e57020. doi: 10.3791/57020
  178. Wong, S.Z.H.; Scott, E.P.; Mu, W.; Guo, X.; Borgenheimer, E.; Freeman, M.; Ming, G.-L.; Wu, Q.-F.; Song, H.; Nakagawa, Y. In vivo clonal analysis reveals spatiotemporal regulation of thalamic nucleogenesis. PLoS Biology, 2018, 16, e2005211. doi: 10.1371/journal.pbio.2005211
  179. Kidwell, C.U.; Su, C.-Y.; Hibi, M.; Moens, C.B. Multiple zebrafish atoh1 genes specify a diversity of neuronal types in the zebrafish cerebellum. Developmental Biology, 2018, 438(1), 44–56. doi: 10.1016/j.ydbio.2018.03.004
  180. Larsen, K.P.; Mathiharan, Y.K.; Kappel, K.; Coey, A.T.; Chen, D.-H.; Barrero, D.; Madigan, L.; Puglisi, J.D.; Skiniotis, G.; Puglisi, E.V. Architecture of an HIV-1 reverse transcriptase initiation complex. Nature, 2018, 557, 118–122. doi: 10.1038/s41586-018-0055-9
  181. Bhatnagar, S.; Verma, K.D.; Hu, Y.; Khera, E.; Priluck, A.; Smith, D.E.; Thurber, G.M. Oral Administration and Detection of a Near-Infrared Molecular Imaging Agent in an Orthotopic Mouse Model for Breast Cancer Screening. Molecular Pharmaceutics, 2018, 15(5), 1746–1754. doi: 10.1021/acs.molpharmaceut.7b00994
  182. Peng, S.; Wang, W.; Chen, C. Surface Transient Binding Based Fluorescence Correlation Spectroscopy (STB-FCS), a Simple and Easy-to-Implement Method to Extend the Upper Limit of Time Window to Seconds. The Journal of Physical Chemistry B, 2018, 122(18), 4844–4850. doi: 10.1021/acs.jpcb.8b03476
  183. Wang, H.; Dai, T.; Li, S.; Zhou, S.; Yuan, X.; You, J.; Wang, C.; Mukwaya, V.; Zhou, G.; Liu, G.; Wei, X.; Dou, H. Scalable and cleavable polysaccharide nanocarriers for the delivery of chemotherapy drugs. Acta Biomaterialia, 2018, 72, 206–216. doi: 10.1016/j.actbio.2018.03.024
  184. Li, L.; Wang, C.; Huang, Q.; Xiao, J.; Zhang, Q.; Cheng, Y. A Degradable Hydrogel formed by Dendrimer-encapsulated Platinum Nanoparticle and Oxidized Dextran for Repeated Photothermal Cancer Therapy. Journal of Materials Chemistry B, 2018, 6(16), 2474–2480. doi: 10.1039/C8TB00091C
  185. Gupta, S.; M-Redmond, T; Meng, F.; Tidball, A.; Akil, H.; Watson, S.; Parent, J.M.; Uhler, M.; others. Fibroblast Growth Factor 2 Regulates Activity and Gene Expression of Human Postmitotic Excitatory Neuron. Journal of Neurochemistry, 2018, 145(3), 188–203. doi: 10.1111/jnc.14255
  186. Lee, K.; Zhang, L.; Yi, Y.; Wang, X.; Yu, Y. Rupture of Lipid Membranes Induced by Amphiphilic Janus Nanoparticles. ACS Nano, 2018, 12(4), 3646–3657. doi: 10.1021/acsnano.8b00759
  187. Lyu, Z.; Kang, L.; Buuh, Z.Y.; Jiang, D.; McGuth, J.C.; Du, J.; Wissler, H.L.; Cai, W.; Wang, R.E. A Switchable Site-Specific Antibody Conjugate. ACS Chemical Biology, 2018, 13(4), 958–964. doi: 10.1021/acschembio.8b00107
  188. Li, L.; Yang, J.; Wang, J.; Kopeček, J. Amplification of CD20 Cross-Linking in Rituximab-Resistant B-Lymphoma Cells Enhances Apoptosis Induction by Drug-Free Macromolecular Therapeutics. ACS Nano, 2018, 12(4), 3658–3670. doi: 10.1021/acsnano.8b00797
  189. Su, H.; Liu, Z.; Liu, Y.; Ma, V.P.-Y.; Blanchard, A.; Zhao, J.; Galior, K.; Dyer, R.B.; Salaita, K. Light-Responsive Polymer Particles as Force Clamps for the Mechanical Unfolding of Target Molecules. Nano Letters, 2018, 18(4), 2630–2636. doi: 10.1021/acs.nanolett.8b00459
  190. Sobotzki, N.; Schafroth, M.A.; Rudnicka, A.; Koetemann, A.; Marty, F.; Goetze, S.; Yamauchi, Y.; Carreira, E.M.; Wollscheid, B. HATRIC-based identification of receptors for orphan ligands. Nature Communications, 2018, 9, 1519. doi: 10.1038/s41467-018-03936-z
  191. Mietlicki-Baase, E.G.; Liberini, C.G.; Workinger, J.L.; Bonaccorso, R.L.; Borner, T.; Reiner, D.J.; Koch-Laskowski, K.; McGrath, L.E.; Lhamo, R.; Stein, L.M.; De Jonghe, B.C.; Holz, G.G.; Roth, C.L.; Doyle, R.P.; Hayes, M.R. A Vitamin B12 Conjugate of Exendin-4 Improves Glucose Tolerance Without Associated Nausea or Hypophagia in Rodents. Diabetes, Obesity & Metabolism, 2018, 20(5), 1223–1234. doi: 10.1111/dom.13222
  192. Gulati, N.M.; Pitek, A.S.; Czapar, A.E.; Stewart, P.L.; Steinmetz, N.F. The in vivo fates of plant viral nanoparticles camouflaged using self-proteins: overcoming immune recognition. Journal of Materials Chemistry B, 2018, 6(15), 2204–2216. doi: 10.1039/C7TB03106H
  193. Wojcik, F.; Dann, G.P.; Beh, L.Y.; Debelouchina, G.T.; Hofmann, R.; Muir, T.W. Functional crosstalk between histone H2B ubiquitylation and H2A modifications and variants. Nature Communications, 2018, 9, 1394. doi: 10.1038/s41467-018-03895-5
  194. Stadler, D.; Siribbal, S.M.; Gessner, I.; Öz, S.; Ilyas, S.; Mathur, S. Asymmetric attachment and functionalization of plasmonic nanoparticles on ceramic interfaces. Journal of Nanostructure in Chemistry, 2018, 8(1), 33–44. doi: 10.1007/s40097-018-0252-y
  195. He, H.; Chen, Y.; Li, Y.; Song, Z.; Zhong, Y.; Zhu, R.; Cheng, J.; Yin, L. Effective and Selective Anti-Cancer Protein Delivery via All-Functions-in-One Nanocarriers Coupled with Visible Light-Responsive, Reversible Protein Engineering. Advanced Functional Materials, 2018, 28(14), 1706710. doi: 10.1002/adfm.201706710
  196. Gadkari, V.V.; Harvey, S.R.; Raper, A.T.; Chu, W.-T.; Wang, J.; Wysocki, V.H.; Suo, Z. Investigation of sliding DNA clamp dynamics by single-molecule fluorescence, mass spectrometry and structure-based modeling. Nucleic Acids Research, 2018, 46(6), 3103–3118. doi: 10.1093/nar/gky125
  197. Huang, D.; Chen, Y.-S.; Green, C.R.; Rupenthal, I.D. Hyaluronic acid coated albumin nanoparticles for targeted peptide delivery in the treatment of retinal ischaemia. Biomaterials, 2018, 168, 10–23. doi: 10.1016/j.biomaterials.2018.03.034
  198. Nemmara, V.J.; Subramanian, V.; Muth, A.; Mondal, S.; Salinger, A.J.; Maurais, A.J.; Tilvawala, R.; Weerapana, E.; Thompson, P.R. The Development of Benzimidazole-Based Clickable Probes for the Efficient Labeling of Cellular Protein Arginine Deiminases (PADs). ACS Chemical Biology, 2018, 13(3), 712–722. doi: 10.1021/acschembio.7b00957
  199. Kim, H.-Y.; Wang, X.; Kang, R.; Tang, D.; Boone, B.A.; Zeh, H.J.; Lotze, M.T.; Edwards, W.B. RAGE-specific single chain Fv for PET imaging of pancreatic cancer. PLoS One, 2018, 13(3), e0192821. doi: 10.1371/journal.pone.0192821
  200. Gaspar, I.; Hövelmann, F.; Chamiolo, J.; Ephrussi, A.; Seitz, O. Quantitative mRNA Imaging with Dual Channel qFIT Probes to Monitor Distribution and Degree of Hybridization. ACS Chemical Biology, 2018, 13(3), 742–749. doi: 10.1021/acschembio.7b01007
  201. Zhang, X.; He, F.; Xiang, K.; Zhang, J.; Xu, M.; Long, P.; Su, H.; Gan, Z.; Yu, Q. CD44-targeted Facile Enzymatic Activatable Chitosan Nanoparticles for Efficient Antitumor Therapy and Reversal of Multidrug Resistance. Biomacromolecules, 2018, 19(3), 883–895. doi: 10.1021/acs.biomac.7b01676
  202. Lee, A.; Kim, S.H.; Lee, H.; Kim, B.; Kim, Y.S.; Key, J. Visualization of MMP-2 Activity Using Dual-Probe Nanoparticles to Detect Potential Metastatic Cancer Cells. Nanomaterials, 2018, 8(2), 119. doi: 10.3390/nano8020119
  203. Maudens, P.; Seemayer, C.A.; Thauvin, C.; Gabay, C.; Jordan, O.; Allémann, E. Nanocrystal-Polymer Particles: Extended Delivery Carriers for Osteoarthritis Treatment. Small, 2018, 14(8), 1703108. doi: 10.1002/smll.201703108
  204. Cai, H.; Wang, X.; Zhang, H.; Sun, L.; Pan, D.; Gong, Q.; Gu, Z.; Luo, K. Enzyme-sensitive biodegradable and multifunctional polymeric conjugate as theranostic nanomedicine. Applied Materials Today, 2018, 11, 207–218. doi: 10.1016/j.apmt.2018.02.003
  205. Yang, W.; Cao, Y.; Zhang, Z.; Du, F.; Shi, Y.; Li, X.; Zhang, Q. Targeted delivery of FGF2 to subchondral bone enhanced the repair of articular cartilage defect. Acta Biomaterialia, 2018, 69, 170–182. doi: 10.1016/j.actbio.2018.01.039
  206. Raper, A.T.; Stephenson, A.A.; Suo, Z. Functional Insights Revealed by the Kinetic Mechanism of CRISPR/Cas9. Journal of the American Chemical Society, 2018, 140(8), 2971–2984. doi: 10.1021/jacs.7b13047
  207. Liu, Z.; Wang, S.; Li, W.; Tian, Y. Bioimaging and Biosensing of Ferrous Ion in Neurons and HepG2 Cells Upon Oxidative Stress. Analytical Chemistry, 2018, 90(4), 2816–2825. doi: 10.1021/acs.analchem.7b04934
  208. Murata, H.; Carmali, S.; Baker, S.L.; Matyjaszewski, K.; Russell, A.J. Solid-phase synthesis of protein-polymers on reversible immobilization supports. Nature Communications, 2018, 9, 845. doi: 10.1038/s41467-018-03153-8
  209. Jani, S.; Jackson, A.; Davies-Sala, C.; Chiem, K.; Soler-Bistué, A.; Zorreguieta, A.; Tolmasky, M.E. Assessment of External Guide Sequences' (EGS) Efficiency as Inducers of RNase P-Mediated Cleavage of mRNA Target Molecules. Methods in Molecular Biology, 2018, 1737, 89–98. doi: 10.1007/978-1-4939-7634-8_6
  210. Alric, C.; Hervé-Aubert, K.; Aubrey, N.; Melouk, S.; Lajoie, L.; Même, W.; Même, S.; Courbebaisse, Y.; Ignatova, A.A.; Feofanov, A.V.; Chourpa, I.; Allard-Vannier, E. Targeting HER2-breast tumors with scFv-decorated bimodal nanoprobes. Journal of Nanobiotechnology, 2018, 16, 18. doi: 10.1186/s12951-018-0341-6
  211. Poreba, M.; Rut, W.; Vizovisek, M.; Groborz, K.; Kasperkiewicz, P.; Finlay, D.; Vuori, K.; Turk, D.; Turk, B.; Salvesen, G.; Drag, M. Selective imaging of human cathepsin L in breast cancer by fluorescent activity-based probes. Chemical Science, 2018, 9(8), 2113–2129. doi: 10.1039/C7SC04303A
  212. Wang, Y.; Qiao, S.-L.; Wang, H. Facile Synthesis of Peptide-Crosslinked Nanogels for Tumor Metastasis Inhibition. ACS Applied Nano Materials, 2018, 1(2), 785–792. doi: 10.1021/acsanm.7b00203
  213. Raghupathi, K.; Skinner, M.; Chang, G.; Crawley, C.; Yoshida-Moriguchi, T.; Pipenhagen, P.; Zhu, Y.; Avila, L.Z.; Miller, R.J.; Dhal, P.K. Hyaluronic Acid Microgels as Intracellular Endosomolysis Reagents. ACS Biomaterials Science & Engineering, 2018, 4(2), 558–565. doi: 10.1021/acsbiomaterials.7b00966
  214. Xie, H.; Shao, J.; Ma, Y.; Wang, J.; Huang, H.; Yang, N.; Wang, H.; Ruan, C.; Luo, Y.; Wang, Q.-Q.; Chuc, P.K.; Yu, X.-F. Biodegradable near-infrared-photoresponsive shape memory implants based on black phosphorus nanofillers. Biomaterials, 2018, 164, 11–21. doi: 10.1016/j.biomaterials.2018.02.040
  215. Cheng, T.; Zhang, Y.; Liu, J.; Ding, Y.; Ou, H.; Huang, F.; An, Y.; Liu, Y.; Liu, J.; Shi, L. Ligand-Switchable Micellar Nanocarriers for Prolonging Circulation Time and Enhancing Targeting Efficiency. ACS Applied Materials & Interfaces, 2018, 10(6), 5296–5304. doi: 10.1021/acsami.7b18137
  216. Long, M.J.C.; Urul, D.A.; Chawla, S.; Lin, H.-Y.; Zhao, Y.; Haegele, J.A.; Wang, Y.; Aye, Y. Precision Electrophile Tagging in Caenorhabditis elegans. Biochemistry, 2018, 57(2), 216–220. doi: 10.1021/acs.biochem.7b00642
  217. Jeschke, A.; Haas, A. Sequential actions of phosphatidylinositol phosphates regulate phagosome-lysosome fusion. Molecular Biology of the Cell, 2018, 29(4), 452–465. doi: 10.1091/mbc.E17-07-0464
  218. Zhao, Y.; Zhang, W.; Li, C. Optimization of the conical mirror design based on Monte Carlo simulations for fluorescence molecular tomography. SPIE Proceedings: Multimodal Biomedical Imaging XIII, 2018, 10487, 104870M. doi: 10.1117/12.2290665
  219. Zhao, M.; Steffen, F.D.; and Börner, R.; Schaffer, M.F.; Sigel, R.K.O.; Freisinger, E. Site-specific dual-color labeling of long RNAs for single-molecule spectroscopy. Nucleic Acids Research, 2018, 46(3), e13. doi: 10.1093/nar/gkx1100
  220. Andrianova, M.; Komarova, N.; Grudtsov, V.; Kuznetsov, E.; Kuznetsov, A. Amplified Detection of the Aptamer-Vanillin Complex with the Use of Bsm DNA Polymerase. Sensors, 2018, 18, 49. doi: 10.3390/s18010049
  221. Ghai, A.; Maji, D.; Rettig, M.; Chanswangphuwana, C.; DiPersio, J.; Akers, W.; Achilefu, S.; Dehdashti, F.; Vij, R.; Shokeen, M. Preclinical development of CD38-targeted [89Zr]Zr-DFO-daratumumab for imaging multiple myeloma. Journal of Nuclear Medicine, 2018, 59(2), 216–222. doi: 10.2967/jnumed.117.196063
  222. Tal, N.; Rudnick-Glick, S.; Grinberg, I.; Natan, M.; Banin, E.; Margel, S. Engineering of a New Bisphosphonate Monomer and Nanoparticles of Narrow Size Distribution for Antibacterial Applications. ACS Omega, 2018, 3(2), 1458–1469. doi: 10.1021/acsomega.7b01686
  223. Lam, R.; Gondin, A.B.; Canals, M.; Kellam, B.; Briddon, S.J.; Graham, B.; Scammells, P.J. Fluorescently Labelled Morphine Derivatives for Bioimaging Studies. Journal of Medicinal Chemistry, 2018, 61(3), 1316–1329. doi: 10.1021/acs.jmedchem.7b01811
  224. Jun, D.; Minic, Z.; Bhat, S.V.; Vanderlinde, E.M.; Yost, C.K.; Babu, M.; Dahms, T.E.S. Metabolic Adaptation of a C-Terminal Protease A-Deficient Rhizobium leguminosarum in Response to Loss of Nutrient Transport. Frontiers in Microbiology, 2018, 8, 2617. doi: 10.3389/fmicb.2017.02617
  225. He, H.; Markoutsa, E.; Li, J.; Xu, P. Repurposing Disulfiram for Cancer Therapy via Targeted Nanotechnology through Enhanced Tumor Mass Penetration and Disassembly. Acta Biomaterialia, 2018, 68, 113–124. doi: 10.1016/j.actbio.2017.12.023
  226. Rambarran, T.; Gonzaga, F.; Fatona, A.; Coulson, M.; Saem, S.; Moran-Mirabal, J.; Brook, M.A. Bonding and in-channel microfluidic functionalization using the huisgen cyclization. ournal of Polymer Science Part A: Polymer Chemistry, 2018, 56(6), 589–597. doi: 10.1002/pola.28930
  227. Sallada, N.D.; Dunn, K.J.; Berger, B.W. A structural and functional role for disulfide bonds in a class II hydrophobin. Biochemistry, 2018, 57(5), 645–653. doi: 10.1021/acs.biochem.7b01166
  228. Condon, S.G.F.; Mahbuba, D.-A.; Armstrong, C.R.; Díaz-Vázquez, G.; Craven, S.J.; LaPointe, L.M.; Khadria, A.S.; Chadda, R.; Crooks, J.A.; Rangarajan, N.; Weibel, D.B.; Hoskins, A.A.; Robertson, J.L.; Cui, Q.; Senes, A. The FtsLB sub-complex of the bacterial divisome is tetramer with an uninterrupted FtsL helix linking the transmembrane and periplasmic regions. Journal of Biological Chemistry, 2018, 293(5), 1623–1641. doi: 10.1074/jbc.RA117.000426
  229. Grube, L.; Dellen, R.; Kruse, F.; Schwender, H.; Stuehler, K.; Poschmann, G. Mining the secretome of C2C12 muscle cells: Data dependent experimental approach to analyze protein secretion using label-free quantification and peptide based analysis. Journal of Proteome Research, 2018, 17(2), 879–890. doi: 10.1021/acs.jproteome.7b00684
  230. Kim, H.; Shin, K.; Park, O.K.; Choi, D.; Kim, H.D.; Baik, S.; Lee, S.H.; Kwon, S.-H.; Yarema, K.J.; Hong, J.; Hyeon, T.; Hwang, N.S. General and Facile Coating of Single Cells via Mild Reduction. Journal of the American Chemical Society, 2018, 140(4), 1199–1202. doi: 10.1021/jacs.7b08440
  231. Cho, U.; Riordan, D.P.; Ciepla, P.; Kocherlakota, K.S.; Chen, J.K.; Harbury, P.B. Ultrasensitive optical imaging with lanthanide lumiphores. Nature Chemical Biology, 2018, 14(1), 15–21. doi: 10.1038/nchembio.2513
  232. Jasinski, D.L.; Yin, H.; Li, Z.; Guo, P. The Hydrophobic Effect from Conjugated Chemicals or Drugs on in Vivo Biodistribution of RNA Nanoparticles. Human Gene Therapy, 2018, 29(1), 77–86. doi: 10.1089/hum.2017.054
  233. Li, L.; Yang, J.; Wang, J.; Kopeček, J. Drug-Free Macromolecular Therapeutics Induce Apoptosis via Calcium Influx and Mitochondrial Signaling Pathway. Macromolecular Bioscience, 2018, 1, 1700196. doi: 10.1002/mabi.201700196
  234. Park, J.; Hwang, S.R.; Choi, J.U.; Alam, F.; Byun, Y. Self-assembled nanocomplex of PEGylated protamine and heparin–suramin conjugate for accumulation at the tumor site. International Journal of Pharmaceutics, 2018, 535(1–2), 38–46. doi: 10.1016/j.ijpharm.2017.10.055
  235. Hori, A.; Kurata, S.; Kuraishi, T. Unexpected role of the IMD pathway in Drosophila gut defense against Staphylococcus aureus. Biochemical and Biophysical Research Communications, 2018, 495(1), 395–400. doi: 10.1016/j.bbrc.2017.11.004
  236. Penn, C.; Yang, K.; Zong, H.; Lim, J.-Y.; Cole, A.; Yang, D.; Baker, J.; Goonewardena, S.N.; Buckanovich, R.J. Therapeutic Impact of Nanoparticle Therapy Targeting Tumor Associated Macrophages. Molecular Cancer Therapeutics, 2018, 17(1), 96–106. doi: 10.1158/1535-7163.MCT-17-0688
  237. Maudens, P.; Meyer, S.; Seemayer, C.A.; Jordan, O.; Allémann, E. Self-assembled thermoresponsive nanostructures of hyaluronic acid conjugates for osteoarthritis therapy. Nanoscale, 2018, 10(4), 1845–1854. doi: 10.1039/C7NR07614B
  238. Jaworski, E.; Routh, A. ClickSeq: Replacing Fragmentation and Enzymatic Ligation with Click-Chemistry to Prevent Sequence Chimeras. Methods in Molecular Biology, 2018, 1712, 71–85. doi: 10.1007/978-1-4939-7514-3_6
  239. Wijnands, S.P.W.; Engelen, W.; Lafleur, R.P.M.; Meijer, E.W.; Merkx, M. Controlling protein activity by dynamic recruitment on a supramolecular polymer platform. Nature Communications, 2018, 9, 65. doi: 10.1038/s41467-017-02559-0
  240. Locke, L.W.; Kothandaraman, S.; Tweedle, M.; Chaney, S.; Wozniak, D.; Schlesinger, L.S. Use of a leukocyte-targeted peptide probe as a potential tracer for imaging the tuberculosis granuloma. Tuberculosis, 2018, 108, 201–210. doi: 10.1016/j.tube.2018.01.001
  241. Agrawalla, B.K.; Wang, T.; Riegger, A.; Domogalla, M.P.; Steinbrink, K.; Dörfler, T.; Chen, X.; Boldt, F.; Lamla, M.; Michaelis, J.; Kuan, S.L.; Weil, T. Chemoselective Dual and Triple Labelling of Native and Recombinant Proteins. Bioconjugate Chemistry, 2018, 29(1), 29–34. doi: 10.1021/acs.bioconjchem.7b00675
  242. Yao, L.; Li, Q.; Guan, Y.; Zhu, X.X.; Zhang, Y. Tetrahedral, Octahedral, and Triangular Dipyramidal Microgel Clusters with Thermosensitivity Fabricated from Binary Colloidal Crystals Template and Thiol–Ene Reaction. ACS Macro Letters, 2018, 7, 80–84. doi: 10.1021/acsmacrolett.7b00935
  243. Wu, Y.; Zhang, L.; Cui, C.; Cansiz, S.; Liang, H.; Wu, C.; Teng, I.-T.; Chen, W.; Liu, Y.; Hou, W.; Zhang, X.; Tan, W. Enhanced Targeted Gene Transduction: AAV2 Vectors Conjugated to Multiple Aptamers via Reducible Disulfide Linkages. Journal of the American Chemical Society, 2018, 140(1), 2–5. doi: 10.1021/jacs.7b08518
  244. Miragoli, M.; Ceriotti, P.; Iafisco, M.; Vacchiano, M.; Salvarani, N.; Alogna, A.; Carullo, P.; Ramirez-Rodríguez, G.B.; Patrício, T.; Esposti, L.D.; Rossi, F.; Ravanetti, F.; Pinelli, S.; Alinovi, R.; Erreni, M.; Rossi, S.; Condorelli, G.; Post, H.; Tampieri, A.; Catalucci, D. Inhalation of peptide-loaded nanoparticles improves heart failure. Science Translational Medicine, 2018, 10(424), eaan6205. doi: 10.1126/scitranslmed.aan6205
  245. Mansour, V.J.; Coorssen, J.R. Quantitative Gel Electrophoresis. In: de Almeida, A.; Eckersall, D.; Miller, I. (eds) Proteomics in Domestic Animals: from Farm to Systems Biology. Springer, Cham, 2018, pp 17–35. doi: 10.1007/978-3-319-69682-9_3
  246. Ou, H.; Cheng, T.; Zhang, Y.; Liu, J.; Ding, Y.; Zhen, J.; Shen, W.; Xu, Y.; Yang, W.; Niu, P.; Liu, J.; An, Y.; Liu, Y.; Shi, L. Surface-adaptive Zwitterionic Nanoparticles for Prolonged Blood Circulation Time and Enhanced Cellular Uptake in Tumor Cells. Acta Biomaterialia, 2018, 65, 339–348. doi: 10.1016/j.actbio.2017.10.034
  247. Giulbudagian, M.; Yealland, G.; Hönzke, S.; Edlich, A.; Geisendörfer, B.; Kleuser, B.; Hedtrich, S.; Calderón, M. Breaking the Barrier-Potent Anti-Inflammatory Activity following Efficient Topical Delivery of Etanercept using Thermoresponsive Nanogels. Theranostics, 2018, 8(2), 450–463. doi: 10.7150/thno.21668
  248. Ashcheulova, D.O.; Efimova, L.V.; Lushchyk, A.Y.; Yantsevich, A.V.; Baikov, A.N.; Pershina, A.G. Production of the recombinant antimicrobial peptide UBI18–35 in Escherichia coli. Protein Expression and Purification, 2018, 143, 38–44. doi: 10.1016/j.pep.2017.10.011
  249. Sato, S.-I.; Yatsuzuka, K.; Katsuda, Y.; Uesugi, M. Method for Imaging Live-Cell RNA Using an RNA Aptamer and a Fluorescent Probe. Methods in Molecular Biology, 2018, 1649, 305–318. doi: 10.1007/978-1-4939-7213-5_20
  250. Tian, T.; Zhang, H.-X.; He, C.-P.; Fan, S.; Zhu, Y.-L.; Qi, C.; Huang, N.-P.; Xiao, Z.-D.; Lu, Z.-H.; Tannous, B.A.; Gao, J. Surface functionalized exosomes as targeted drug delivery vehicles for cerebral ischemia therapy. Biomaterials, 2018, 150, 137–149. doi: 10.1016/j.biomaterials.2017.10.012
  251. Cioloboc, D.; Kennedy, C.; Boice, E.N.; Clark, E.R.; Kurtz, D.M. A Trojan Horse for Light-Triggered Bifurcated Production of Singlet Oxygen and Fenton-Reactive Iron Within Cancer Cells. Biomacromolecules, 2018, 19(1), 178–187. doi: 10.1021/acs.biomac.7b01433
  252. Das, S.; Haedicke, K.; Grimm, J. Cerenkov-activated sticky tag for in vivo fluorescence imaging. Journal of Nuclear Medicine, 2018, 59(1), 58–65. doi: 10.2967/jnumed.117.198549
  253. Kuznetsov, A.; Komarova, N.; Andrianova, M.; Grudtsov, V.; Kuznetsov, E. Aptamer based vanillin sensor using an ion-sensitive field-effect transistor. Microchimica Acta, 2018, 185(1), 3. doi: 10.1007/s00604-017-2586-4
  254. Newman, M.R.; Russell, S.G.; Schmitt, C.S.; Marozas, I.A.; Sheu, T.-J.; Puzas, J.E.; Benoit, D.S.W. Multivalent Presentation of Peptide Targeting Groups Alters Polymer Biodistribution to Target Tissues. Biomacromolecules, 2018, 19(1), 71–84. doi: 10.1021/acs.biomac.7b01193
  255. Timin, A.S.; Muslimov, A.R.; Lepik, K.V.; Epifanovskaya, O.S:; Shakirova, A.I.; Mock, U.; Riecken, K.; Okilova, M.V.; Sergeev, V.S.; Afanasyev, B.V.; Fehse, B.; Sukhorukov, G.B. Efficient gene editing via non-viral delivery of CRISPR-Cas9 system using polymeric and hybrid microcarriers. Nanomedicine: Nanotechnology, Biology, and Medicine, 2018, 14(1), 97–108. doi: 10.1016/j.nano.2017.09.001
  256. Lockhart, J.N.; Spoonmore, T.J.; McCurdy, M.W.; Rogers, B.R.; Guelcher, S.A.; Harth, E. Poly(glycidol) Coating on Ultrahigh Molecular Weight Polyethylene for Reduced Biofilm Growth. ACS Applied Materials & Interfaces, 2018, 10(4), 4050–4056. doi: 10.1021/acsami.7b15981
  257. Ding, L.; Jiang, Y.; Zhang, J.; Klok, H.-A.; Zhong, Z. pH-Sensitive Coiled-Coil Peptide-Cross-Linked Hyaluronic Acid Nanogels: Synthesis and Targeted Intracellular Protein Delivery to CD44 Positive Cancer Cells. Biomacromolecules, 2018, 19(2), 555–562. doi: 10.1021/acs.biomac.7b01664
  258. Park, C.-K.; Hong, S.K.; Kim, Y.H.; Cho, H. Nucleic acid-binding fluorochromes and nanoparticles: Structural aspects of binding affinity and fluorescence intensity. Macromolecular Research, 2018, 26(2), 204–209. doi: 10.1007/s13233-018-6053-8
  259. Kong, J.-N.; Zhu, Z.; Itokazu, Y.; Wang, G.; Dinkins, M.B.; Zhong, L.; Lin, H.-P.; Elsherbini, A.; Leanhart, S.; Jiang, X.; Qin, H.; Zhi, W.; Spassieva, S.D.; Bieberich, E. Novel function of ceramide for regulation of mitochondrial ATP release in astrocytes. Journal of Lipid Research, 2018, 59(3), 488–506. doi: 10.1194/jlr.M081877
  260. Huang, D.; Chen, Y.-S.; Xu, Q.; Hanes, J.; Rupenthal, I.D. Effects of enzymatic degradation on dynamic mechanical properties of the vitreous and intravitreal nanoparticle mobility. European Journal of Pharmaceutical Sciences, 2018, 118, 124–133. doi: 10.1016/j.ejps.2018.03.023
  261. Fatona, A.; Berry, R.M.; Brook, M.A.; Moran-Mirabal, J.M. Versatile Surface Modification of Cellulose Fibres and Cellulose Nanocrystals through Modular Triazinyl Chemistry. Chemistry of Materials, 2018, 30(7), 2424–2435. doi: 10.1021/acs.chemmater.8b00511
  262. Huang, Q.; Li, S.; Ding, Y.; Yin, H.; Wang, L.-H.; Wang, R. Macrocycle-Wrapped Polyethylenimine for Gene Delivery with Reduced Cytotoxicity. Biomaterials Science, 2018, 6(5), 1031–1039. doi: 10.1039/C8BM00022K
  263. Matsuoka, D.; Watanabe, H.; Shimizu, Y.; Kimura, H.; Yagi, Y.; Kawai, R.; Ono, M.; Saji, H. Structure–activity relationships of succinimidyl-Cys-C (O)-Glu derivatives with different near-infrared fluorophores as optical imaging probes for prostate-specific membrane antigen. Bioorganic & Medicinal Chemistry, 2018, 26(9), 2291–2301. doi: 10.1016/j.bmc.2018.03.015
  264. Zhai, M.; Wang, Y.; Zhang, L.; Liang, M.; Fu, S.; Cui, L.; Yang, M.; Gong, W.; Li, Z.; Yu, L.; Xie, X.; Yang, C.; Yang, Y.; Gao, C. Glioma targeting peptide modified apoferritin nanocage. Drug Delivery, 2018, 25(1), 1013-1024. doi: 10.1080/10717544.2018.1464082
  265. Yang, D.H.; Kim, H.J.; Park, K.; Kim, J.K.; Chun, H.J. Preparation of poly- l -lysine-based nanoparticles with pH-sensitive release of curcumin for targeted imaging and therapy of liver cancer in vitro and in vivo. Drug Delivery, 2018, 25(1), 950-960. doi: 10.1080/10717544.2018.1461957
  266. Zhang, Z.; Li, H.; Xu, G.; Yao, P. Liver-targeted delivery of insulin-loaded nanoparticles via enterohepatic circulation of bile acids. Drug Delivery, 2018, 25(1), 1224-1233. doi: 10.1080/10717544.2018.1469685
  267. Sim, T.; Kim, J.E.; Hoang, N.H.; Kang, J.K.; Lim, C.; Kim, D.S.; Lee, E.S.; Youn, Y.S.; Choi, H.-G.; Han, H.-K.; Weon, K.-Y.; Oh, K.T. Development of a docetaxel micellar formulation using poly(ethylene glycol)–polylactide–poly(ethylene glycol) (PEG–PLA–PEG) with successful reconstitution for tumor targeted drug delivery. Drug Delivery, 2018, 25(1), 1362-1371. doi: 10.1080/10717544.2018.1477865

2017

  1. Wang, K.; Cheng, F.; Pan, X.; Zhou, T.; Liu, X.; Zheng, Z.; Luo, L.; Zhang, Y. Investigation of the transport and absorption of Angelica sinensis polysaccharide through gastrointestinal tract both in vitro and in vivo. Drug Delivery, 2017, 24(1), 1360-1371. doi: 10.1080/10717544.2017.1375576
  2. Mattila, J.T.; Beaino, W.; Maiello, P.; Coleman, M.T.; White, A.G.; Scanga, C.A.; Flynn, J.A.; Anderson, C.J. Positron Emission Tomography Imaging of Macaques with Tuberculosis Identifies Temporal Changes in Granuloma Glucose Metabolism and Integrin α4β1-Expressing Immune Cells. Journal of immunology, 2017, 199(2), 806–815. doi: 10.4049/jimmunol.1700231
  3. Chen, J.; Ding, J.; Wang, Y.; Cheng, J.; Ji, S.; Zhuang, X.; Chen, X. Sequentially Responsive Shell-Stacked Nanoparticles for Deep Penetration into Solid Tumors. Advanced Materials, 2017, 29(32), 1701170. doi: 10.1002/adma.201701170
  4. Shields, K.J.; Wu, C. Differential Adipose Tissue Proteomics. Methods in Molecular Biology, 2017, 1788, 243–250. doi: 10.1007/7651_2017_80
  5. Evans, L.E.; Jones, K.; Cheeseman, M.D. Targeting secondary protein complexes in drug discovery: studying the druggability and chemical biology of the HSP70/BAG1 complex. Chemical Communications, 2017, 53(37), 5167–5170. doi: 10.1039/c7cc01376k
  6. Wang, C.; Niederstrasser, H.; Douglas, P.M.; Lin, R.; Jaramillo, J.; Li, Y.; Olswald, N.W.; Zhou, A.; McMillan, E.A.; Mendiratta, S.; Wang, Z.; Zhao, T.; Lin, Z.; Luo, M.; Huang, G.; Brekken, R.A.; Posner, B.A.; MacMillan, J.B.; Gao, J.; White, M.A. Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan. Nature Communications, 2017, 8, 2270. doi: 10.1038/s41467-017-02332-3
  7. Maximova, N.; Koroleva, A.; Sitnikova, T.; Khanaev, I.; Bukin, Y.; Kirilchik, S. Age Dynamics of Telomere Length of Baikal Gastropods is Sex Specific and Multidirectional. Folia Biologica (Kraków), 2017, 65(4), 187–197. doi: 10.3409/fb65_4.187
  8. Lee, N.K.; Lee, E.J.; Kim, S.; Nam, G.-H.; Kih, M.; Hong, Y.; Jeong, C.; Yang, Y.; Byun, Y.; Kim, I.-S. Ferritin nanocage with intrinsically disordered proteins and affibody: A platform for tumor targeting with extended pharmacokinetics. Journal of Controlled Release, 2017, 267, 172–180. doi: 10.1016/j.jconrel.2017.08.014
  9. Madl, C.M.; LeSavage, B.L.; Dewi, R.E.; Dinh, C.B.; Stowers, R.S.; Khariton, M.; Lampe, K.J.; Nguyen, D.; Chaudhuri, O.; Enejder, A.; Heilshorn, S.C. Maintenance of neural progenitor cell stemness in 3D hydrogels requires matrix remodelling. Nature Materials, 2017, 16(12), 1233–1242. doi: 10.1038/nmat5020
  10. Hu, H.; Xiao, C.; Wu, H.; Li, Y.; Zhou, Q.; Tang, Y.; Yu, C.; Yang, X.; Li, Z. Nanocolloidosomes with Selective Drug Release for Active Tumor-Targeted Imaging-Guided Photothermal/Chemo Combination Therapy. ACS Applied Materials & Interfaces, 2017, 9(48), 42225–42238. doi: 10.1021/acsami.7b14796
  11. Zhou, Z.; Jafari, M.; Sriram, V.; Kim, J.; Lee, J.-Y.; Ruiz-Torres, S.J.; Waltz, S.E. Delayed Sequential Co-Delivery of Gefitinib and Doxorubicin for Targeted Combination Chemotherapy. Molecular Pharmaceutics, 2017, 14(12), 4551–4559. doi: 10.1021/acs.molpharmaceut.7b00669
  12. Chen, G.; Ma, B.; Wang, Y.; Xie, R.; Li, C.; Dou, K.; Gong, S. CuS-Based Theranostic Micelles for NIR-Controlled Combination Chemotherapy and Photothermal Therapy and Photoacoustic Imaging. ACS Applied Materials & Interfaces, 2017, 9(48), 41700–41711. doi: 10.1021/acsami.7b14083
  13. Topolyan, A.P.; Belyaeva, M.; Slyundina, M.S.; Ilyushenkova, V.; Formanovsky, A.A.; Korshun, V.A.; Borisov, R.S. Novel trityl/acridine derivatization agent for analysis of thiols by (matrix-assisted)(nanowire-assisted) laser desorption/ionization and electrospray ionization mass spectrometry. Analytical Methods, 2017, 9(45), 6335–6340. doi: 10.1039/C7AY01965C
  14. Zhou, J.; He, L.; Pang, Z.; Appelman, H.D.; Kuick, R.; Beer, D.G.; Li, M.; Wang, T.D. Identification and validation of FGFR2 peptide for detection of early Barrett's neoplasia. Oncotarget, 2017, 8(50), 87095–87106. doi: 10.18632/oncotarget.19764
  15. Lee, J.-H.; Yang, B.; Lindahl, A.J.; Damaschke, N.; Boersma, M.D.; Huang, W.; Corey, E.; Jarrard, D.F.; Denu, J.M. Identifying dysregulated epigenetic enzyme activity in castrate-resistant prostate cancer development. ACS Chemical Biology, 2017, 12(11), 2804–2814. doi: 10.1021/acschembio.6b01035
  16. Schmidt, N.; Kollewe, A.; Constantin, C.E.; Henrich, S.; Ritzau-Jost, A.; Bildl, W.; Saalbach, A.; Hallermann, S.; Kulik, A.; Fakler, B.; Schulte, U. Neuroplastin and Basigin Are Essential Auxiliary Subunits of Plasma Membrane Ca2+-ATPases and Key Regulators of Ca2+ Clearance. Neuron, 2017, 96(4), 827–838.e9. doi: 10.1016/j.neuron.2017.09.038
  17. Niessen, S.; Dix, M.M.; Barbas, S.; Potter, Z.E.; Lu, S.; Brodsky, O.; Planken, S.; Behenna, D.; Almaden, C.; Gajiwala, K.S.; Ryan, K.; Ferre, R.; Lazear, M.R.; Hayward, M.M.; Kath, J.C.; Cravatt, B.F. Proteome-wide Map of Targets of T790M-EGFR-Directed Covalent Inhibitors. Cell Chemical Biology, 2017, 24(11), 1388–1400.e7. doi: 10.1016/j.chembiol.2017.08.017
  18. Schonhoft, J.D.; Monteiro, C.; Plate, L.; Eisele, Y.S.; Kelly, J.M.; Boland, D.; Parker, C.G.; Cravatt, B.F.; Teruya, S.; Helmke, S.; Maurer, M.; Berk, J.; Sekijima, Y.; Novais, M.; Coelho, T.; Powers, E.T.; Kelly, J.W. Peptide probes detect misfolded transthyretin oligomers in plasma of hereditary amyloidosis patients. Science Translational Medicine, 2017, 9(407), eaam7621. doi: 10.1126/scitranslmed.aam7621
  19. Than, A.; Liang, K.; Xu, S.; Sun, L.; Duan, H.; Xi, F.; Xu, C.; Chen, P. Transdermal Delivery of Anti-Obesity Compounds to Subcutaneous Adipose Tissue with Polymeric Microneedle Patches. Small Methods, 2017, 1(11), 1700269. doi: 10.1002/smtd.201700269
  20. Li, Y.; Han, Z.; Roelle, S.; DeSanto, A.; Sabatelle, R.; Schur, R.; Lu, Z.-R. Synthesis and Assessment of Peptide Gd-DOTA Conjugates Targeting Extradomain B Fibronectin for Magnetic Resonance Molecular Imaging of Prostate Cancer. Molecular Pharmaceutics, 2017, 14(11), 3906–3915. doi: 10.1021/acs.molpharmaceut.7b00619
  21. Feiner-Gracia, N.; Beck, M.; Pujals, S.; Tosi, S.; Mandal, T.; Buske, C.; Linden, M.; Albertazzi, L. Super-Resolution Microscopy Unveils Dynamic Heterogeneities in Nanoparticle Protein Corona. Small, 2017, 13(41), 1701631. doi: 10.1002/smll.201701631
  22. Zabara, A.; Meikle, T.G.; Trenker, R.; Yao, S.; Newman, J.; Peat, T.S.; Separovic, F.; Conn, C.E.; Call, M.J.; Call, M.E.; Landau, E.M.; Drummond, C.J. Lipidic Cubic Phase-Induced Membrane Protein Crystallization: Interplay Between Lipid Structure, Mesophase Properties, and Crystallogenesis. Crystal Growth and Design, 2017, 17(11), 5667–5674. doi: 10.1021/acs.cgd.7b00519
  23. Liu, L.; Zhang, C.; Li, Z.; Wang, C.; Bi, J.; Yin, S.; Wang, Q.; Yu, R.; Liu, Y.D.; Su, Z. Albumin binding domain fusing R/K-X-X-R/K sequence for enhancing tumor delivery of doxorubicin. Molecular Pharmaceutics, 2017, 14(11), 3739–3749. doi: 10.1021/acs.molpharmaceut.7b00497
  24. Liu, Y.; Ji, X.; Liu, J.; Tong, W.W.L.; Askhatova, D.; Shi, J. Tantalum Sulfide Nanosheets as a Theranostic Nanoplatform for Computed Tomography Imaging-Guided Combinatorial Chemo-Photothermal Therapy. Advanced Functional Materials, 2017, 27(39), 1703261. doi: 10.1002/adfm.201703261
  25. Deyaert, E.; Wauters, L.; Guaitoli, G.; Konijnenberg, A.; Leemans, M.; Terheyden, S.; Petrovic, A.; Gallardo, R.; Nederveen-Schippers, L.M.; Athanasopoulos, P.S.; Pots, H.; Van Haastert, P.J.M.; Sobott, F.; Gloeckner, C.J.; Efremov, R.; Kortholt, A.; Versées, W. A homologue of the Parkinson's disease-associated protein LRRK2 undergoes a monomer-dimer transition during GTP turnover. Nature Communications, 2017, 8(1), 1008. doi: 10.1038/s41467-017-01103-4
  26. Park, S.; Shevlin, E.; Vedvyas, Y.; Zaman, M.; Park, S.; Hsu, Y.-M.S.; Min, I.M.; Jin, M.M. Micromolar affinity CAR T cells to ICAM-1 achieves rapid tumor elimination while avoiding systemic toxicity. Scientific Reports, 2017, 7, 14366. doi: 10.1038/s41598-017-14749-3
  27. Zhou, Z.; Liu, S.; Zhang, Y.; Yang, X.; Ma, Y.; Guan, Z.; Wu, Y.; Zhang, L.; Yang, Z. Reductive nanocomplex encapsulation of cRGD-siRNA conjugates for enhanced targeting to cancer cells. International Journal of Nanomedicine, 2017, 12, 7255–7272. doi: 10.2147/ijn.S136726
  28. Xie, J.; Yang, C.; Liu, Q.; Li, J.; Liang, R.; Shen, C.; Zhang, Y.; Wang, K.; Liu, L.; Shezad, K.; Sullivan, M.; Xu, Y.; Shen, G.; Tao, J.; Zhu, J.; Zhang, Z. Encapsulation of Hydrophilic and Hydrophobic Peptides into Hollow Mesoporous Silica Nanoparticles for Enhancement of Antitumor Immune Response. Small, 2017, 13(40), 1701741. doi: 10.1002/smll.201701741
  29. Rachel, N.M.; Toulouse, J.L.; Pelletier, J.N. Transglutaminase-Catalyzed Bioconjugation Using One-Pot Metal-Free Bioorthogonal Chemistry. Bioconjugate Chemistry, 2017, 28(10), 2518–2523. doi: 10.1021/acs.bioconjchem.7b00509
  30. Schäfer, O.; Klinker, K.; Braun, L.; Huesmann, D.; Schultze, J.; Koynov, K.; Barz, M. Combining Orthogonal Reactive Groups in Block Copolymers for Functional Nanoparticle Synthesis in a Single Step. ACS Macro Letters, 2017, 6(10), 1140–1145. doi: 10.1021/acsmacrolett.7b00678
  31. Mitronova, G.Y.; Lukinavičius, G.; Butkevich, A.N.; Kohl, T.; Belov, V.N.; Lehnart, S.E.; Hell, S.W. High-Affinity Functional Fluorescent Ligands for Human β-Adrenoceptors. Scientific Reports, 2017, 7, 12319. doi: 10.1038/s41598-017-12468-3
  32. Xiao, W.; Ruan, S.; Yu, W.; Wang, R.; Hu, C.; Liu, R.; Gao, H. Normalizing tumor vessels to increase the enzyme-induced retention and targeting of gold nanoparticle for breast cancer imaging and treatment. Molecular Pharmaceutics, 2017, 14(10), 3489–3498. doi: 10.1021/acs.molpharmaceut.7b00475
  33. Xu, W.; Ding, J.; Chen, X. Reduction-Responsive Polypeptide Micelles for Intracellular Delivery of Antineoplastic Agent. Biomacromolecules, 2017, 18(10), 3291–3301. doi: 10.1021/acs.biomac.7b00950
  34. Pink, M.; Verma, N.; Zerries, A.; Schmitz-Spanke, S. Dose-dependent response to 3-nitrobenzanthrone exposure in human urothelial cancer cells. Chemical Research in Toxicology, 2017, 30(10), 1855–1864. doi: 10.1021/acs.chemrestox.7b00174
  35. Sharangdhar, T.; Sugimoto, Y.; Heraud-Farlow, J.; Fernández-Moya, S.M.; Ehses, J.; Ruiz de Los Mozos, I.; Ule, J.; Kiebler, M.A. A retained intron in the 3'-UTR of Calm3 mRNA mediates its Staufen2- and activity-dependent localization to neuronal dendrites. EMBO Reports, 2017, 18(10), 1762–1774. doi: 10.15252/embr.201744334
  36. Ozcelik, D.; Jain, A.; Stambaugh, A.; Stott, M.A.; Parks, J.W.; Hawkins, A.; Schmidt, H. Scalable Spatial-Spectral Multiplexing of Single-Virus Detection Using Multimode Interference Waveguides. Scientific Reports, 2017, 7, 12199. doi: 10.1038/s41598-017-12487-0
  37. Zhao, P.; George, J.V.; Li, B.; Amini, N.; Paluh, J.; Wang, J. Clickable Multifunctional Dumbbell Particles for In Situ Multiplex Single-Cell Cytokine Detection. ACS Applied Materials & Interfaces, 2017, 9(38), 32482–32488. doi: 10.1021/acsami.7b08338
  38. Wang, E.; Hunter, C.P. SID-1 Functions in Multiple Roles To Support Parental RNAi in Caenorhabditis elegans. Genetics, 2017, 207(2), 547–557. doi: 10.1534/genetics.117.300067
  39. Han, Z.; Wu, X.; Roelle, S.; Chen, C.; Schiemann, W.P.; Lu, Z.-R. Targeted gadofullerene for sensitive magnetic resonance imaging and risk-stratification of breast cancer. Nature Communications, 2017, 8, 692. doi: Nature Communications
  40. Guttenplan, A.P.M.; Young, L.J.; Matak-Vinkovic, D.; Kaminski, C.F.; Knowles, T.P.J.; Itzhaki, L.S. Nanoscale click-reactive scaffolds from peptide self-assembly. Journal of Nanobiotechnology, 2017, 15, 70. doi: 10.1186/s12951-017-0300-7
  41. Shi, X.; Yu, C.Y.Y.; Su, H.; Kwok, R.T.K.; Jiang, M.; He, Z.; Lam, J.W.Y.; Tang, B.Z. A Red-emissive antibody–AIEgen conjugate for turn-on and wash-free imaging of specific cancer cells. Chemical Science, 2017, 8(10), 7014–7024. doi: 10.1039/C7SC01054K
  42. Machado, Y.; Duinkerken, S.; Hoepflinger, V.; Mayr, M.; Korotchenko, E.; Kurtaj, A.; Pablos, I.; Steiner, M.; Stoecklinger, A.; Lübbers, J.; Schmid, M.; Ritter, U.; Scheiblhofer, S.; Ablinger, M.; Wally, V.; Hochmann, S.; Raninger, A.M.; Strunk, D.; van Kooyk, Y.; Thalhamer, J.; Weiss, R. Synergistic effects of dendritic cell targeting and laser-microporation on enhancing epicutaneous skin vaccination efficacy. Journal of Controlled Release, 2017, 266, 87–99. doi: 10.1016/j.jconrel.2017.09.020
  43. Zhang, L.; Yao, M.; Yan, W.; Liu, X.; Jiang, B.; Qian, Z.; Gao, Y.; Lu, X.-J.; Chen, X.; Wang, Q.-L. Delivery of a chemotherapeutic drug using novel hollow carbon spheres for esophageal cancer treatment. International Journal of Nanomedicine, 2017, 12, 6759–6769. doi: 10.2147/IJN.S142916
  44. Steffen, W.; Ko, F.C.; Patel, J.; Lyamichev, V.; Albert, T.; Benz, J.; Rudolph, M.G.; Bergmann, F.; Streidl, T.; Kratzsch, P.; Boenitz-Dulat, M.; Oelschlaegel, T.; Schraeml, M. Discovery of a microbial transglutaminase enabling highly site-specific labeling of proteins. Journal of Biological Chemistry, 2017, 292(38), 15622–15635. doi: 10.1074/jbc.M117.797811
  45. Park, J.; Choi, J.U.; Kim, K.; Byun, Y. Bile acid transporter mediated endocytosis of oral bile acid conjugated nanocomplex. Biomaterials, 2017, 147, 145–154. doi: 10.1016/j.biomaterials.2017.09.022
  46. Pan, G.; Jia, T.-t.; Huang, Q.-x. Qiu, Y.-y.; Xu, J. Yin, P.-h.; Liu, T. Mesoporous Silica Nanoparticles (MSNs)-Based Organic/Inorganic Hybrid Nanocarriers Loading 5-Fluorouracil for the Treatment of Colon Cancer with Improved Anticancer Efficacy. Colloids and Surfaces, B: Biointerfaces, 2017, 159, 375–385. doi: 10.1016/j.colsurfb.2017.08.013
  47. Huang, Y.; Zhou, J.; Hakamivala, A.; Wu, J.; Hong, Y.; Borrelli, J.; Tang, L. An optical probe for detecting chondrocyte apoptosis in response to mechanical injury. Scientific Reports, 2017, 7, 10906. doi: 10.1038/s41598-017-10653-y
  48. Wei, S.; Perera, M.L.W.; Sakhtemani, R.; Bhagwat, A.S. A novel class of chemicals that react with abasic sites in DNA and specifically kill B cell cancers. PLoS One, 2017, 12, e0185010. doi: 10.1371/journal.pone.0185010
  49. Soni, K.S.; Lei, F.; Desale, S.S.; Marky, L.A.; Cohen, S.M.; Bronich, T.K. Tuning polypeptide-based micellar carrier for efficient combination therapy of ErbB2-positive breast cancer. Journal of Controlled Release, 2017, 264, 276–287. doi: 10.1016/j.jconrel.2017.08.038
  50. Duret, D.; Grassin, A.; Henry, M.; Jacquet, T.; Thoreau, F.; Denis-Quanquin, S.; Coll, J.-L.; Boturyn, D.; Favier, A.; Charreyre, M.-T. "Polymultivalent" Polymer-Peptide Cluster Conjugates for an Enhanced Targeting of Cells Expressing αvβ3 Integrins. Bioconjugate Chemistry, 2017, 28(9), 2241–2245. doi: 10.1021/acs.bioconjchem.7b00362
  51. Kim, J.-w.; Heu, W.; Jeong, S.; Kim, H.-S. Genetically functionalized ferritin nanoparticles with a high-affinity protein binder for immunoassay and imaging. Analytica Chimica Acta, 2017, 988, 81–88. doi: 10.1016/j.aca.2017.07.060
  52. Schneider, J.R.; Carias, A.M.; Bastian, A.R.; Cianci, G.C.; Kiser, P.F.; Veazey, R.S.; Hope, T.J. Long-term direct visualization of passively transferred fluorophore-conjugated antibodies. Journal of Immunological Methods, 2017, 450, 66–72. doi: 10.1016/j.jim.2017.07.009
  53. Verardi, R.; Kim, J.-S.; Ghirlando, R.; Banerjee, A. Structural Basis for Substrate Recognition by the Ankyrin Repeat Domain of Human DHHC17 Palmitoyltransferase. Structure, 2017, 25(9), 1337–1347. doi: 10.1016/j.str.2017.06.018
  54. Mondal, G.; Almawash, S.; Chaudhary, A.K.; Mahato, R.I. EGFR-Targeted Cationic Polymeric Mixed Micelles for Co-delivery of Gemcitabine and miR-205 for treating Advanced Pancreatic Cancer. Molecular Pharmaceutics, 2017, 14(9), 3121–3133. doi: 10.1021/acs.molpharmaceut.7b00355
  55. Chen, Z.; Zhai, M.; Xie, X.Y.; Zhang, Y.; Ma, S.; Li, Z.; Yu, F.; Zhao, B.; Zhang, M.; Yang, Y.; Mei, X. Apoferritin Nanocage for Brain Targeted Doxorubicin Delivery. Molecular Pharmaceutics, 2017, 14(9), 3087–3097. doi: 10.1021/acs.molpharmaceut.7b00341
  56. Gaspar, I.; Wippich, F.; Ephrussi, A. Enzymatic production of single molecule FISH and RNA capture probes. RNA, 2017, 23(10), 1582–1591. doi: 10.1261/rna.061184.117
  57. Li, Z.; Xiong, Y. Cytoplasmic E3 ubiquitin ligase CUL9 controls cell proliferation, senescence, apoptosis and genome integrity through p53. Oncogene, 2017, 36(36), 5212–5218. doi: 10.1038/onc.2017.141
  58. Huang, T.-Y.; Chang, C.-K.; Kao, Y.-F.; Chin, C.-H.; Ni, C.-W.; Hsu, H.-Y.; Hu, N.-J.; Hsieh, L.-C.; Chou, S.-H.; Lee, I.-R.; Hou, M.-H. Parity-dependent hairpin configurations of repetitive DNA sequence promote slippage associated with DNA expansion. Proceedings of the National Academy of Sciences of the USA, 2017, 114(36), 9535–9540. doi: 10.1073/pnas.1708691114
  59. Haimi, P.; Vinskiene, J.; Stepulaitiene, I.; Baniulis, D.; Stanienė, G.; Šikšnianienė, J.B.; Rugienius, R. Patterns of low temperature-Induced accumulation of dehydrins in Rosaceae crops — Evidence for post-translational modification in apple. Journal of Plant Physiology, 2017, 218, 175–181. doi: 10.1016/j.jplph.2017.08.008
  60. Payne, W.M.; Hill, T.K.; Svechkarev, D.; Holmes, M.B.; Sajja, B.R.; Mohs, A.M. Multimodal Imaging Nanoparticles Derived from Hyaluronic Acid for Integrated Preoperative and Intraoperative Cancer Imaging. Contrast Media & Molecular Imaging, 2017, 2017, Article ID 9616791. doi: 10.1155/2017/9616791
  61. Wollhofen, R.; Buchegger, B.; Eder, C.; Jacak, J.; Kreutzer, J.; Klar, T.A. Functional photoresists for sub-diffraction stimulated emission depletion lithography. Optical Materials Express, 2017, 7(7), 2538–2559. doi: 10.1364/ome.7.002538
  62. Wang, H.; Chen, J.; Xu, C.; Shi, L.; Tayier, M.; Zhou, J.; Zhang, J.; Wu, J.; Ye, Z.; Fang, T.; Han, W. Cancer Nanomedicines Stabilized by π–π Stacking between Heterodimeric Prodrugs Enable Exceptionally High Drug Loading Capacity and Safer Delivery of Drug Combinations. Theranostics, 2017, 7(15), 3639–3652. doi: 10.7150/thno.20028
  63. Kovalenko, Y.; Sotiri, I.; Timonen, J.V.I.; Overton, J.C.; Holmes, G.; Aizenberg, J.; Howell, C. Bacterial Interactions with Immobilized Liquid Layers. Advanced Healthcare Materials, 2017, 6(15), 1600948. doi: 10.1002/adhm.201600948
  64. Steele, A.N.; Cai, L.; Truong, V.N.; Edwards, B.B.; Goldstone, A.B.; Eskandari, A.; Mitchell, A.C.; Marquardt, L.M.; Foster, A.A.; Cochran, J.R.; Heilshorn, S.C.; Woo, Y.J. A novel protein-engineered hepatocyte growth factor analog released via a shear-thinning injectable hydrogel enhances post-infarction ventricular function. Biotechnology and Bioengineering, 2017, 114(10), 2379–2389. doi: 10.1002/bit.26345
  65. Wang, F.; Sun, W.; Li, L.; Li, L.; Liu, Y.; Zhang, Z.; Huang, Y. Charge-reversible Multi-functional HPMA Copolymers for Mitochondrial Targeting. ACS Applied Materials & Interfaces, 2017, 9(33), 27563–27574. doi: 10.1021/acsami.7b09693
  66. Fu, L.; Han, L.; Xie, C.; Li, W.; Lin, L.; Pan, S.; Zhou, Y.; Li, Z.; Jin, M.; Zhang, A. Identification of Extracellular Actin As a Ligand for Triggering Receptor Expressed on Myeloid Cells-1 Signaling. Frontiers in Immunology, 2017, 8, 917. doi: 10.3389/fimmu.2017.00917
  67. Zhang, C.; Moonshi, S.S.; Han, Y.; Puttick, S.; Peng, H.; Magoling, B.J.A.; Reid, J.C.; Bernardi, S.; Searles, D.J.; Král, P.; Whittaker, A.K. PFPE-Based Polymeric 19F MRI Agents: A New Class of Contrast Agents with Outstanding Sensitivity. Macromolecules, 2017, 50(15), 5953–5963. doi: 10.1021/acs.macromol.7b01285
  68. Antos, J.M.; Ingram, J.; Fang, T.; Pishesha, N.; Truttmann, M.C.; Ploegh, H.L. Site-Specific Protein Labeling via Sortase-Mediated Transpeptidation. Current Protocols in Protein Science, 2017, 89, 15.3.1–15.3.19. doi: 10.1002/cpps.38
  69. Zhou, Z.; Kennell, C.; Jafari, M.; Lee, J.-Y.; Ruiz-Torres, S.J.; Waltz, S.E.; Lee, J.-H. Sequential Delivery of Erlotinib and Doxorubicin for Enhanced Triple Negative Breast Cancer Treatment Using Polymeric Nanoparticle. International Journal of Pharmaceutics, 2017, 530(1–2), 300–307. doi: 10.1016/j.ijpharm.2017.07.085
  70. Pettersson, J.R.; Lanni, F.; Rule, G.S. Dual lifetimes for complexes between Glutathione-S-transferase (hGSTA1-1) and product-like ligands detected by single-molecule fluorescence imaging. Biochemistry, 2017, 56(31), 4073–4083. doi: 10.1021/acs.biochem.7b00030
  71. Dou, Y.; Chen, Y.; Zhang, X.; Xu, X.; Chen, Y.; Guo, J.; Zhang, D.; Wang, R.; Li, X.; Zhang, J. Non-proinflammatory and responsive nanoplatforms for targeted treatment of atherosclerosis. Biomaterials, 2017, 143, 93–108. doi: 10.1016/j.biomaterials.2017.07.035
  72. Chen, G.; Wang, Y.; Xie, R.; Gong, S. Tumor-targeted pH/redox dual-sensitive unimolecular nanoparticles for efficient siRNA delivery. Journal of Controlled Release, 2017, 259, 105–114. doi: 10.1016/j.jconrel.2017.01.042
  73. Sun, S.; Li, L.; Yang, F.; Wang, X.; Fan, F.; Yang, M.; Chen, C.; Li, X.; Wang, H.-W.; Sui, S.-F. Cryo-EM structures of the ATP-bound Vps4E233Q hexamer and its complex with Vta1 at near-atomic resolution. Nature Communications, 2017, 8, 16064. doi: 10.1038/ncomms16064
  74. Tsai, M.-H.; Pan, C.-H.; Peng, C.-L.; Shieh, M.-J. Panitumumab-Conjugated Pt-Drug Nanomedicine for Enhanced Efficacy of Combination Targeted Chemotherapy against Colorectal Cancer. Advanced Healthcare Materials, 2017, 6(13), 1700111. doi: 10.1002/adhm.201700111
  75. Kozlowska, A.K.; Florczak, A.; Smialek, M.; Dondajewska, E.; Mackiewicz, A.; Kortylewski, M.; Dams-Kozlowska, H. Functionalized bioengineered spider silk spheres improve nuclease resistance and activity of oligonucleotide therapeutics providing a strategy for cancer treatment. Acta Biomaterialia, 2017, 59, 221–233. doi: 10.1016/j.actbio.2017.07.014
  76. Zhang, C.; Yang, L.; Ding, Y.; Wang, Y.; Lan, L.; Ma, Q.; Chi, X.; Wei, P.; Zhao, Y.; Steinbüchel, A.; Zhang, H.; Liu, P. Bacterial lipid droplets bind to DNA via an intermediary protein that enhances survival under stress. Nature Communications, 2017, 8, 15979. doi: 10.1038/ncomms15979
  77. Suleimanov, I.; Gabor, M.; Lionel, S.; Bousseksou, A. Near-infrared luminescence switching in a spin-crossover polymer nanocomposite. European Journal of Inorganic Chemistry, 2017, 28, 3446–3451. doi: 10.1002/ejic.201700426
  78. Merjaneh, M.; Langlois, A.; Larochelle, S.; Cloutier, C.B.; Ricard-Blum, S.; Moulin, V.J. Pro-angiogenic capacities of microvesicles produced by skin wound myofibroblasts. Angiogenesis, 2017, 20(3), 385–398. doi: 10.1007/s10456-017-9554-9
  79. Segura-Ibarra, V.; Cara, F.E.; Wu, S.; Iruegas-Nunez, D.A.; Wang, S.; Ferrari, M.; Ziemys, A.; Valderrabano, M.; Blanco, E. Nanoparticles administered intrapericardially enhance payload myocardial distribution and retention. Journal of Controlled Release, 2017, 262, 18–27. doi: 10.1016/j.jconrel.2017.07.012
  80. Wilson, D.R.; Routkevitch, D.; Rui, Y.; Mosenia, A.; Wahlin, K.J.; Quinones-Hinojosa, A.; Zack, D.J.; Green, J.J. A Triple-Fluorophore Labeled Nucleic Acid pH Nanosensor to Investigate Non-Viral Gene Delivery. Molecular Therapy, 2017, 25(7), 1697–1709. doi: 10.1016/j.ymthe.2017.04.008
  81. Lin, P.-Y.; Chuang, E.-Y.; Chiu, Y.-H.; Chen, H.-L.; Lin, K.-J.; Juang, J.-H.; Chiang, C.-H.; Mi, F.-L.; Sung, H.-W. Safety and efficacy of self-assembling bubble carriers stabilized with sodium dodecyl sulfate for oral delivery of therapeutic proteins. Journal of Controlled Release, 2017, 259, 168–175. doi: 10.1016/j.jconrel.2016.12.018
  82. Xu, X.; Saw, P.E.; Tao, W.; Li, Y.; Ji, X.; Yu, M.; Mahmoudi, M.; Rasmussen, J.; Ayyash, D.; Zhou, Y.; Farokhzad, O.C.; Shi, J. Tumor Microenvironment-Responsive Multistaged Nanoplatform for Systemic RNAi and Cancer Therapy. Nano Letters, 2017, 17(7), 4427–4435. doi: 10.1021/acs.nanolett.7b01571
  83. Loebel, C.; Rodell, C.B.; Chen, M.H.; Burdick, J.A. Shear-thinning and self-healing hydrogels as injectable therapeutics and for 3D-printing. Nature Protocols, 2017, 12(8), 1521–1541. doi: 10.1038/nprot.2017.053
  84. Rosier, B.J.H.M.; Cremers, G.A.O.; Engelen, W.; Merkx, M.; Brunsveld, L.; de Greef, T.F.A. Incorporation of native antibodies and Fc-fusion proteins on DNA nanostructures via a modular conjugation strategy. Chemical Communications, 2017, 53, 7393–7396. doi: 10.1039/c7cc04178k
  85. Barnett, D.; Liu, Y.; Partyka, K.; Huang, Y.; Tang, H.; Hostetter, G.; Brand, R.E.; Singhi, A.D.; Drake, R.R.; Haab, B.B. The CA19-9 and Sialyl-TRA Antigens Define Separate Subpopulations of Pancreatic Cancer Cells. Scientific Reports, 2017, 7, 4020. doi: 10.1038/s41598-017-04164-z
  86. Zhao, Y.; Wang, Y.; Ran, F.; Cui, Y.; Liu, C.; Zhao, Q.; Gao, Y.; Wang, D.; Wang, S. A comparison between sphere and rod nanoparticles regarding their in vivo biological behavior and pharmacokinetics. Scientific Reports, 2017, 7, 4131. doi: 10.1038/s41598-017-03834-2
  87. Seeger, C.; Talibov, V.O.; Danielson, U.H. Biophysical analysis of the dynamics of calmodulin interactions with neurogranin and Ca2+/calmodulin-dependent kinase II. Journal of Molecular Recognition, 2017, 30(8), e2621. doi: 10.1002/jmr.2621
  88. Routh, A.; Ji, P.; Jaworski, E.; Xia, Z.; Li, W.; Wagner, E.J. Poly(A)-ClickSeq: click-chemistry for next-generation 3′-end sequencing without RNA enrichment or fragmentation. Nucleic Acids Research, 2017, 45(12), e112. doi: 10.1093/nar/gkx286
  89. Han, S.; Son, H.Y.; Kang, B.; Jang, E.; Ki, J.; Lee, N.G.; Park, J.; Shin, M.-K.; Mun, B.; Min, J.-K.; Haam, S. Fluorescent nanoswitch for monitoring specific pluripotency-related microRNAs of induced pluripotent stem cells: Development of polyethyleneimineoligonucleotide hybridization probes. Nano Research, 2017, 10(8), 2545–2559. doi: 10.1007/s12274-016-1403-4
  90. Sikorskaite-Gudziuniene, S.; Haimi, P.; Gelvonauskiene, D.; Stanys, V. Nuclear proteome analysis of apple cultivar ‘Antonovka’ accessions in response to apple scab (Venturia inaequalis). European Journal of Plant Pathology, 2017, 148(4), 771–784. doi: 10.1007/s10658-016-1131-3
  91. Bloch, M.B.D.; Yavin, E.; Nissan, A.; Ariel, I.; Kenett, R.; Brass, D.; Rubinstein, A. The effect of linker type and recognition peptide conjugation chemistry on tissue affinity and cytotoxicity of charged polyacrylamide. Journal of Controlled Release, 2017, 257, 102–117. doi: 10.1016/j.jconrel.2016.06.038
  92. Ruan, S.; Xiao, W.; Hu, C.; Zhang, H.; Rao, J.; Wang, S.; Wang, X.; He, Q.; Gao, H. Ligand Mediated and Enzyme-Directed Precise Targeting and Retention for Enhanced Treatment of Glioblastoma. ACS Applied Materials & Interfaces, 2017, 9(24), 20348–20360. doi: 10.1021/acsami.7b02303
  93. Zhou, Z.; Yan, Y.; Hu, K.; Zou, Y.; Li, Y.; Ma, R.; Zhang, Q.; Cheng, Y. Autophagy inhibition enabled efficient photothermal therapy at a mild temperature. Biomaterials, 2017, 141, 116–124. doi: 10.1016/j.biomaterials.2017.06.030
  94. Treerattrakoon, K., Chanthima, W.; Apiwat, C.; Dharakul, T.; Bamrungsap, S. Oriented conjugation of antibodies against~the epithelial cell adhesion molecule on fluorescently doped silica nanoparticles for flow-cytometric determination and in vivo imaging of EpCAM, a biomarker for colorectal cancer. Microchimica Acta, 2017, 184(7), 1941–1950. doi: 10.1007/s00604-017-2211-6
  95. Summer, D.; Grossrubatscher, L.; Petrik, M.; Michalcikova, T.; Novy, Z.; Rangger, C.; Klingler, M.; von Guggenberg, E.; Haubner, R.; Kaeopookum, P.; Haas, H.; Decristoforo, C. Developing targeted hybrid imaging probes by chelator scaffolding. Bioconjugate Chemistry, 2017, 28(6), 1722–1733. doi: 10.1021/acs.bioconjchem.7b00182
  96. Mateju, D.; Franzmann, T.M.; Patel, A.; Kopach, A.; Boczek, E.E.; Maharana, S.; Lee, H.O.; Carra, S.; Hyman, A.A.; Alberti, S. An aberrant phase transition of stress granules triggered by misfolded protein and prevented by chaperone function. The EMBO Journal, 2017, 36(12), 1669–1687. doi: 10.15252/embj.201695957
  97. O'Mary, H.L.; Aldayel, A.M.; Valdes, S.A.; Naguib, Y.W.; Li, X.; Salvady, K.; Cui, Z. Acid-sensitive sheddable PEGylated, mannose-modified nanoparticles increase the delivery of betamethasone to chronic inflammation sites in a mouse model. Molecular Pharmaceutics, 2017, 14(6), 1929–1937. doi: 10.1021/acs.molpharmaceut.7b00024
  98. LaBoda, C.D.; Lebeck, A.R.; Dwyer, C.L. An Optically Modulated Self-Assembled Resonance Energy Transfer Pass Gate. Nano Letters, 2017, 17(6), 3775–3781. doi: 10.1021/acs.nanolett.7b01112
  99. Yang, H.Y.; Jang, M.-S.; Li, Y.; Lee, J.H.; Lee, D.S. Multifunctional and Redox-Responsive Self-Assembled Magnetic Nanovectors for Protein Delivery and Dual-Modal Imaging. ACS Applied Materials & Interfaces, 2017, 9(22), 19184–19192. doi: 10.1021/acsami.7b03747
  100. Guo, L.Y.; Allu, P.K.; Zandarashvili, L.; McKinley, K.L.; Sekulic, N.; Dawicki-McKenna, J.M.; Fachinetti, D.; Logsdon, G.A.; Jamiolkowski, R.M.; Cleveland, D.W.; Cheeseman, I.M.; Black, B.E. Centromeres are maintained by fastening CENP-A to DNA and directing an arginine anchor-dependent nucleosome transition. Nature Communications, 2017, 8, 15775. doi: 10.1038/ncomms15775
  101. Wang, Y.; Malcolm, D.W.; Benoit, D.S.W. Controlled and sustained delivery of siRNA/NPs from hydrogels expedites bone fracture healing. Biomaterials, 2017, 139, 127–138. doi: 10.1016/j.biomaterials.2017.06.001
  102. Shabanpoor, F.; Hammond, S.M.; Abendroth, F.; Hazell, G.; Wood, M.J.A.; Gait, M.J. Identification of a Peptide for Systemic Brain Delivery of a Morpholino Oligonucleotide in Mouse Models of Spinal Muscular Atrophy. Nucleic Acid Therapeutics, 2017, 27(3), 130–143. doi: 10.1089/nat.2016.0652
  103. Cho, C.-F.; Wolfe, J.M.; Fadzen, C.M.; Calligaris, D.; Hornburg, K.; Chiocca, E.A.; Agar, N.Y.R.; Pentelute, B.L.; Lawler, S.E. Blood-brain-barrier spheroids as an in vitro screening platform for brain-penetrating agents. Nature Communications, 2017, 8, 15623. doi: 10.1038/ncomms15623
  104. Wang, Y.; Wang, L.; Chen, G.; Gong, S. Carboplatin-Complexed and cRGD-Conjugated Unimolecular Nanoparticles for Targeted Ovarian Cancer Therapy. Macromolecular Bioscience, 2017, 17(5), 1600292. doi: 10.1002/mabi.201600292
  105. Maity, S.; Hashemi, M.; Lyubchenko, Y.L. Nano-assembly of amyloid β peptide: role of the hairpin fold. Scientific Reports, 2017, 7, 2344. doi: 10.1038/s41598-017-02454-0
  106. Lee, Y.; Kischuk, E.; Crist, S.; Ratliff, T.L.; Thompson, D.H. Targeting and Internalization of Liposomes by Bladder Tumor Cells Using a Fibronectin Attachment Protein-Derived Peptide–Lipopolymer Conjugate. Bioconjugate Chemistry, 2017, 28(5), 1481–1490. doi: 10.1021/acs.bioconjchem.7b00153
  107. Sun, W.; Li, L.; Yang, Q.-Q.; Zhang, Z.-R.; Huang, Y. Two birds, one stone: dual targeting of the cancer cell surface and subcellular mitochondria by the galectin-3-binding peptide G3-C12. Acta Pharmacologica Sinica, 2017, 38(6), 806–822. doi: 10.1038/aps.2016.137
  108. Zietzer, A.; Buschmann, E.E.; Janke, D.; Li, L.; Brix, M.; Meyborg, H.; Stawowy, P.; Jungk, C.; Buschmann, I.; Hillmeister, P. Acute Physical Exercise and Long-Term Individual Shear Rate Therapy Increase Telomerase Activity in Human Peripheral Blood Mononuclear Cells. Acta Physiologica, 2017, 220(2), 251–262. doi: 10.1111/apha.12820
  109. Zhang, K.; Zhang, Y.; Li, Z.; Li, N.; Feng, N. Essential oil-mediated glycerosomes increase transdermal paeoniflorin delivery: optimization, characterization, and evaluation in vitro and in vivo. International Journal of Nanomedicine, 2017, 12, 3521–3532. doi: 10.2147/ijn.s135749
  110. George, J.T.; Srivatsan, S.G. Vinyluridine as a Versatile Chemoselective Handle for the Post-transcriptional Chemical Functionalization of RNA. Bioconjugate Chemistry, 2017, 28(5), 1529–1536. doi: 10.1021/acs.bioconjchem.7b00169
  111. Matsuo, Y.; Maurer, S.P.; Surrey, T.; Toda, T. Purification and characterisation of the fission yeast Ndc80 complex. Protein Expression and Purification, 2017, 135, 61–69. doi: 10.1016/j.pep.2017.05.002
  112. Baranova, N.; Loose, M. Single-molecule measurements to study polymerization dynamics of FtsZ-FtsA copolymers. Methods in Cell Biology, 2017, 137, 355–370. doi: 10.1016/bs.mcb.2016.03.036
  113. Lee, J.Y.; Kim, S.E.; Yun, Y.-P.; Choi, S.-W.; Jeon, D.-I.; Kim, H.-J.; Park, K.; Song, H.-R. Osteogenesis and new bone formation of alendronate-immobilized porous PLGA microspheres in a rat calvarial defect model. Journal of Industrial and Engineering Chemistry, 2017, 52, 277–286. doi: 10.1016/j.jiec.2017.03.057
  114. Goto, A.; Yen, H.-C.; Anraku, Y.; Fukushima, S.; Lai, P.-S.; Kato, M.; Kishimura, A.; Kataoka, K. Facile Preparation of Delivery Platform of Water-Soluble Low-Molecular-Weight Drugs Based on Polyion Complex Vesicle (PICsome) Encapsulating Mesoporous Silica Nanoparticle. ACS Biomaterials Science & Engineering, 2017, 3(5), 807–815. doi: 10.1021/acsbiomaterials.6b00562
  115. Balasso, A.; Salmaso, S.; Pontisso, P.; Rosato, A.; Quarta, S.; Malfanti, A.; Mastrotto, F.; Caliceti, P. Re-programming pullulan for targeting and controlled release of doxorubicin to the hepatocellular carcinoma cells. European Journal of Pharmaceutical Sciences, 2017, 103, 104–115. doi: 10.1016/j.ejps.2017.02.016
  116. Jaworski, E.; Routh, A. Parallel ClickSeq and Nanopore sequencing elucidates the rapid evolution of defective-interfering RNAs in Flock House virus. PLOS Pathogens, 2017, 13(5), e1006365. doi: 10.1371/journal.ppat.1006365
  117. Ta, H.T.; Li, Z.; Hagemeyer, C.E.; Cowin, G.; Zhang, S.; Palasubramaniam, J.; Alt, K.; Wang, X.; Peter, K.; Whittaker, A.K. Molecular imaging of activated platelets via antibody-targeted ultra-small iron oxide nanoparticles displaying unique dual MRI contrast. Biomaterials, 2017, 134, 31–42. doi: 10.1016/j.biomaterials.2017.04.037
  118. Zhang, L.; Fang, Y.; Kopeček, J.; Yang, J. A new construct of antibody-drug conjugates for treatment of B-cell non-Hodgkin's lymphomas. European Journal of Pharmaceutical Sciences, 2017, 103, 36–46. doi: 10.1016/j.ejps.2017.02.034
  119. Heller, D.; Helmerhorst, E.J.; Oppenheim, F.G. Saliva and Serum Protein Exchange at the Tooth Enamel Surface. Journal of Dental Research, 2017, 96(4), 437–443. doi: 10.1177/0022034516680771
  120. Wilson, D.R.; Mosenia, A.; Suprenant, M.P.; Upadhya, R.; Routkevitch, D.; Meyer, R.A.; Quinones-Hinojosa, A.; Green, J.J. Continuous Microfluidic Assembly of Biodegradable Poly(beta-amino ester)/DNA Nanoparticles for Enhanced Gene Delivery. Journal of Biomedical Materials Research. Part A, 2017, 105(6), 1813–1825. doi: 10.1002/jbm.a.36033
  121. Brillault, L.; Jutras, P.V.; Dashti, N.; Thuenemann, E.C.; Morgan, G.; Lomonossoff, G.P.; Landsberg, M.J.; Sainsbury, F. Engineering Recombinant Virus-like Nanoparticles from Plants for Cellular Delivery. ACS Nano, 2017, 11(4), 3476–3484. doi: 10.1021/acsnano.6b07747
  122. Daryaee, F.; Zhang, Z.; Gogarty, K.R.; Li, Y.; Merino, J.; Fisher, S.L.; Tonge, P.J. A quantitative mechanistic PK/PD model directly connects Btk target engagement and in vivo efficacy. Chemical Science, 2017, 8(5), 3434–3443. doi: 10.1039/c6sc03306g
  123. Qu, J.-B.; Chapman, R.; Chen, F.; Lu, H.; Stenzel, M.H. Swollen Micelles for the Preparation of Gated, Squeezable, pH-Responsive Drug Carriers. ACS Applied Materials & Interfaces, 2017, 9(16), 13865–13874. doi: 10.1021/acsami.7b01120
  124. Yang, X.; Wang, Z.; Xiang, Z.; Li, D.; Hu, Z.; Cui, W.; Geng, L.; Fang, Q. Peptide probes derived from pertuzumab by molecular dynamics modeling for HER2 positive tumor imaging. PLoS Computational Biology, 2017, 13(4), e1005441. doi: 10.1371/journal.pcbi.1005441
  125. Perez-Anes, A.; Szarpak-Jankowska, A.; Jary, D.; Auzély-Velty, R. β-CD-Functionalized Microdevice for Rapid Capture and Release of Bacteria. ACS Applied Materials & Interfaces, 2017, 9(16), 13928–13938. doi: 10.1021/acsami.7b02194
  126. Bak, D.W.; Pizzagalli, M.D.; Weerapana, E. Identifying Functional Cysteine Residues in the Mitochondria. ACS Chemical Biology, 2017, 12(4), 947–957. doi: 10.1021/acschembio.6b01074
  127. Han, Z.; Li, Y.; Roelle, S.; Zhou, Z.; Liu, Y.; Sabatelle, R.; DeSanto, A.; Yu, X.; Zhu, H.; Magi-Galluzzi, C.; Lu, Z.-R. A Targeted Contrast Agent Specific to an Oncoprotein in Tumor Microenvironment with the Potential for Detection and Risk Stratification of Prostate Cancer with MRI. Bioconjugate Chemistry, 2017, 28(4), 1031–1040. doi: 10.1021/acs.bioconjchem.6b00719
  128. Tondera, C.; Wieduwild, R.; Röder, E.; Werner, C.; Zhang, Y.; Pietzsch, J. In Vivo Examination of an Injectable Hydrogel System Crosslinked by Peptide-Oligosaccharide Interaction in Immunocompetent Nude Mice. In Vivo Examination of an Injectable Hydrogel System Crosslinked by Peptide-Oligosaccharide Interaction in Immunocompetent Nude Mice, 2017, 27(15), 1605189. doi: 10.1002/adfm.201605189
  129. Tang, X.-L.; Yuan, C.-H.; Ding, Q.; Zhou, Y.; Pan, Q.; Zhang, X.-L. Selection and identification of specific glycoproteins and glycan biomarkers of macrophages involved in Mycobacterium tuberculosis infection. Tuberculosis, 2017, 104, 95–106. doi: 10.1016/j.tube.2017.03.010
  130. Zhang, Z.; Yomo, D.; Gradinaru, C. Choosing the right fluorophore for single-molecule fluorescence studies in a lipid environment. Biochimica et Biophysica Acta – Biomembranes, 2017, 1859(7), 1242–1253. doi: 10.1016/j.bbamem.2017.04.001
  131. Revalde, J.L.; Li, Y.; Wijeratne, T.S.; Bugde, P.; Hawkins, B.C.; Rosengren, R.J.; Paxton, J.W. Curcumin and its cyclohexanone analogue inhibited human Equilibrative nucleoside transporter 1 (ENT1) in pancreatic cancer cells. European Journal of Pharmacology, 2017, 803, 167–173. doi: 10.1016/j.ejphar.2017.03.055
  132. Yin, M.; Bao, Y.; Gao, X.; Wu, Y.; Sun, Y.; Zhao, X.; Xu, H.; Zhang, Z.; Tan, S. Redox/pH dual-sensitive hybrid micelles for targeting delivery and overcoming multidrug resistance of cancer. Journal of Materials Chemistry B, 2017, 5(16), 2964–2978. doi: 10.1039/c6tb03282f
  133. Taskova, M.; Uhd, J.; Miotke, L.; Kubit, M.; Bell, J.; Ji, H.P.; Astakhova, K. Tandem Oligonucleotide Probe Annealing and Elongation To Discriminate Viral Sequence. Analytical Chemistry, 2017, 89(8), 4363–4366. doi: 10.1021/acs.analchem.7b00646
  134. Glass, J.J.; Li, Y.; De Rose, R.; Johnston, A.P.R.; Czuba, E.I.; Khor, S.Y.; Quinn, J.F.; Whittaker, M.R.; Davis, T.P.; Kent, S.J. Thiol-Reactive Star Polymers Display Enhanced Association with Distinct Human Blood Components. ACS Applied Materials & Interfaces, 2017, 9(14), 12182-12194. doi: 10.1021/acsami.6b15942
  135. Planken, S.; Behenna, D.C.; Nair, S.K.; Johnson, T.O.; Nagata, A.; Almaden, C.; Bailey, S.; Ballard, T.E.; Bernier, L.; Cheng, H. et al. Discovery of N-((3R, 4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl) amino)-9-methyl-9H-purin-2-yl) pyrrolidine-3-yl) acrylamide (PF-06747775) Through Structure-Based Drug Design; ... Journal of Medicinal Chemistry, 2017, 60(7), 3002–3019. doi: 10.1021/acs.jmedchem.6b01894
  136. Sacoman, J.L.; Dagda, R.Y.; Burnham-Marusich, A.R.; Dagda, R.K.; Berninsone, P.M. Mitochondrial O-GlcNAc transferase (mOGT) regulates mitochondrial structure, function and survival in HeLa cells. Journal of Biological Chemistry, 2017, 292(11), 4499–4518. doi: 10.1074/jbc.M116.726752
  137. Zhang, C.; Zhao, X.; Guo, S.; Lin, T.; Guo, H. Highly effective photothermal chemotherapy with pH-responsive polymer-coated drug-loaded melanin-like nanoparticles. International Journal of Nanomedicine, 2017, 12, 1827–1840. doi: 10.2147/ijn.s130539
  138. Bian, Y.; Deng, X.; Yan, X.; Zhou, J.; Yuan, L.; Yan, Y. Integrated proteomic analysis of Brachypodium distachyon roots and leaves reveals a synergistic network in the response to drought stress and recovery. Scientific Reports, 2017, 7, 46183. doi: 10.1038/srep46183
  139. Perillo, E.; Hervé-Aubert, K.; Allard-Vannier, E.; Falanga, A.; Galdiero, S.; Chourpa, I. Synthesis and in vitro evaluation of fluorescent and magnetic nanoparticles functionalized with a cell penetrating peptide for cancer theranosis. Journal of Colloid and Interface Science, 2017, 499, 209–217. doi: 10.1016/j.jcis.2017.03.106
  140. Malinovskaya, Y.; Melnikov, P.; Baklaushev, V.; Gabashvili, A.; Osipova, N.; Mantrov, S.; Ermolenko, Y.; Maksimenko, O.; Gorshkova, M.; Balabanyan, V.; Kreuter, J.; Gelperina, S. Delivery of doxorubicin-loaded PLGA nanoparticles into U87 human glioblastoma cells. International Journal of Pharmaceutics, 2017, 524(1–2), 77–90. doi: 10.1016/j.ijpharm.2017.03.049
  141. Kubota, T.; Durek, T.; Dang, B.; Finol-Urdaneta, R.K.; Craik, D.J.; Kent, S.B.H.; French, R.J.; Bezanilla, F.; Correa, A.M. Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET. Proceedings of the National Academy of Sciences of the U.S.A., 2017, 114(10), E1857–1865. doi: 10.1073/pnas.1700453114
  142. Wong, A.S.M.; Czuba, E.; Chen, M.Z.; Yuen, D.; Cupic, K.I.; Yang, S.; Hodgetts, R.Y.; Selby, L.I.; Johnston, A.P.R.; Such, G.K. pH-Responsive Transferrin-pHlexi Particles Capable of Targeting Cells in Vitro. ACS Macro Letters, 2017, 6, 315–320. doi: 10.1021/acsmacrolett.7b00044
  143. Taskova, M.; Madsen, C.S.; Jensen, K.J.; Hansen, L.H.; Vester, B.; Astakhova, K. Antisense oligonucleotides internally labeled with peptides show improved target recognition and stability to enzymatic degradation. Bioconjugate Chemistry, 2017, 28(3), 768–774. doi: 10.1021/acs.bioconjchem.6b00567
  144. Gulati, N.M.; Pitek, A.S.; Steinmetz, N.F.; Stewart, P.L. Cryo-electron tomography investigation of serum albumin-camouflaged tobacco mosaic virus nanoparticles. Nanoscale, 2017, 9(10), 3408–3425. doi: 10.1039/c6nr06948g
  145. Pan, Y.; Ren, X.; Wang, S.; Li, X.; Luo, X.; Yin, Z. Annexin V-Conjugated Mixed Micelles as a Potential Drug Delivery System for Targeted Thrombolysis. Biomacromolecules, 2017, 18(3), 865–876. doi: 10.1021/acs.biomac.6b01756
  146. Terekhov, S.S.; Smirnov, I.V.; Stepanova, A.V.; Bobik, T.V.; Mokrushina, Y.A.; Ponomarenko, N.A.; Belogurov, A.A.; Rubtsova, M.P.; Kartseva, O.V.; Gomzikova, M.O.; Moskovtsev, A.A.; Bukatin, A.S.; Dubina, M.V.; Kostryukova, E.S.; Babenko, V.V.; Vakhitova, M.T.; Manolov, A.I.; Malakhova, M.V.; Kornienko, M.A.; Tyakht, A.V.; Vanyushkina, A.A.; Ilina, E.N.; Masson, P.; Gabibov, A.g.; Altman, S. Microfluidic droplet platform for ultrahigh-throughput single-cell screening of biodiversity. Proceedings of the National Academy of Sciences of the U.S.A., 2017, 114(10), 2550–2555. doi: 10.1073/pnas.1621226114
  147. Alqahtani, M.S.; Islam, M.S.; Podaralla, S.; Kaushik, R.S.; Reineke, J.J.; Woyengo, T.; Perumal, O. Food Protein-based Core-Shell Nanocarriers for Oral Drug Delivery: Effect of Shell Composition on in-vitro and in-vivo Functional Performance of Zein Nanocarriers. Molecular Pharmaceutics, 2017, 14(3), 757–769. doi: 10.1021/acs.molpharmaceut.6b01017
  148. Wang, T.; Tang, Y.; He, X.; Yan, J.; Wang, C.; Feng, X. Self-Assembled Raspberry-Like Core/Satellite Nanoparticles for Anti-Inflammatory Protein Delivery. ACS Applied Materials & Interfaces, 2017, 9(8), 6902–6907. doi: 10.1021/acsami.6b16277
  149. Li, N.; Cai, H.; Jiang, L.; Hu, J.; Bains, A.; Hu, J.; Gong, Q.; Luo, K.; Gu, Z. Enzyme-Sensitive and Amphiphilic PEGylated Dendrimer-Paclitaxel Prodrug Based Nanoparticles for Enhanced Stability and Anticancer Efficacy. ACS Applied Materials & Interfaces, 2017, 9(8), 6865–6877. doi: 10.1021/acsami.6b15505
  150. Mandracchia, D.; Rosato, A.; Trapani, A.; Chlapanidas, T.; Montagner, I.M.; Perteghella, S.; Di Franco, C.; Torre, M.L.; Trapani, G.; Tripodo, G. Design, synthesis and evaluation of biotin decorated inulin-based polymeric micelles as long-circulating nanocarriers for targeted drug delivery. Nanomedicine: Nanotechnology, Biology, and Medicine, 2017, 13(3), 1245–1254. doi: 10.1016/j.nano.2017.01.001
  151. Diaz-Romero, J.; Kürsener, S.; Kohl, S.; Nesic, D. S100B+A1 CELISA: A Novel Potency Assay and Screening Tool for Redifferentiation Stimuli of Human Articular Chondrocytes. Journal of Cellular Physiology, 2017, 232(6), 1559–1570. doi: 10.1002/jcp.25682
  152. Konishcheva, E.V.; Zhumaev, U.E.; Meier, W.P. PEO-b-PCL-b-PMOXA Triblock Copolymers: From Synthesis to Microscale Polymersomes with Asymmetric Membrane. Macromolecules, 2017, 50(4), 1512–1520. doi: 10.1021/acs.macromol.6b02743
  153. Yuan, H.; Wilks, M.Q.; Fakhri, G.E.; Normandin, M.D.; Kaittanis, C.; Josephson, L. Heat-induced-radiolabeling and click chemistry: A powerful combination for generating multifunctional nanomaterials. PLoS One, 2017, 12(2), e0172722. doi: 10.1371/journal.pone.0172722
  154. Chen, L.; Weinmeister, R.; Kralovicova, J.; Eperon, L.P.; Vorechovsky, I.; Hudson, A.J.; Eperon, I.C. Stoichiometries of U2AF35, U2AF65 and snRNP reveal new early spliceosome assembly pathways. Nucleic Acids Research, 2017, 45(4), 2051–2067. doi: 10.1093/nar/gkw860
  155. Peng, Z.; Zhou, J.; Dacy, A.; Zhao, D.; Kearney, V.; Zhou, W.; Tang, L.; Hu, W. Design of a portable imager for near-infrared visualization of cutaneous wounds. Journal of Biomedical Optics, 2017, 22(1), 16010. doi: 10.1117/1.jbo.22.1.016010
  156. Hatai, J.; Motiei, L.; Margulies, D. Analyzing Amyloid Beta Aggregates with a Combinatorial Fluorescent Molecular Sensor. Journal of the American Chemical Society, 2017, 139(6), 2136–2139. doi: 10.1021/jacs.6b10809
  157. Zhou, H.; Tourkakis, G.; Shi, D.; Kim, D.M.; Zhang, H.; Du, T.; Eades, W.C.; Berezin, M.Y. Cell-free measurements of brightness of fluorescently labeled antibodies. Scientific Reports, 2017, 7, 41819. doi: 10.1038/srep41819
  158. Mottas, I.; Milosevic, A.; Petri-Fink, A.; Rothen-Rutishauser, B.; Bourquin, C. A rapid screening method to evaluate the impact of nanoparticles on macrophages. Nanoscale, 2017, 9(7), 2492–2504. doi: 10.1039/c6nr08194k
  159. Duan, Z.; Zhang, Y.; Zhu, H.; Sun, L.; Cai, H.; Li, B.; Gong, Q.; Gu, Z.; Luo, K. Stimuli-Sensitive Biodegradable and Amphiphilic Block Copolymer-Gemcitabine Conjugates Self-assemble Into a Nanoscale Vehicle for Cancer Therapy. ACS Applied Materials & Interfaces, 2017, 9(4), 3474–3486. doi: 10.1021/acsami.6b15232
  160. Long, M.J.C.; Parvez, S.; Zhao, Y.; Surya, S.L.; Wang, Y.; Zhang, S.; Aye, Y. Akt3 is a privileged first responder in isozyme-specific electrophile response. Nature Chemical Biology, 2017, 13(3), 333–338. doi: 10.1038/nchembio.2284
  161. Guldris, N.; Argibay, B.; Gallo, J.; Iglesias-Rey, R.; Carbó-Argibay, E.; Kolen'ko, Y.V.; Campos, F.; Sobrino, T.; Salonen, L.M.; Bañobre-López, M.; Castillo, J.; Rivas, J. Magnetite Nanoparticles for Stem Cell Labeling with High Efficiency and Long-Term in Vivo Tracking. Bioconjugate Chemistry, 2017, 28(2), 362–370. doi: 10.1021/acs.bioconjchem.6b00522
  162. Poudyal, R.R.; Nguyen, P.D.M.; Lokugamage, M.P.; Callaway, M.K.; Gavette, J.V.; Krishnamurthy, R.; Burke, D.H. Nucleobase modification by an RNA enzyme. Nucleic Acids Research, 2017, 45(3), 1345–1354. doi: 10.1093/nar/gkw1199
  163. van der Steen, S.C.H.A.; Raavé, R.; Langerak, S.; van Houdt, L.; van Duijnhoven, S.M.J.; van Lith, S.A.M.; Massuger, L.F.A.G.; Daamen, W.F.; Leenders, W.P.; van Kuppevelt, T.H. Targeting the extracellular matrix of ovarian cancer using functionalized, drug loaded lyophilisomes. European Journal of Pharmaceutics and Biopharmaceutics, 2017, 113, 229–239. doi: 10.1016/j.ejpb.2016.12.010
  164. Stephen, Z.R.; Gebhart, R.N.; Jeon, M.; Blair, A.A.; Ellenbogen, R.G.; Silber, J.R.; Zhang, M. pH-Sensitive O6-Benzylguanosine Polymer Modified Magnetic Nanoparticles for Treatment of Glioblastomas. Bioconjugate Chemistry, 2017, 28(1), 194–202. doi: 10.1021/acs.bioconjchem.6b00545
  165. Jang, D.; Lee, Y.M.; Lee, J.; Doh, J.; Kim, W.J. Remission of lymphoblastic leukaemia in an intravascular fluidic environment by pliable drug carrier with a sliding target ligand. Scientific Reports, 2017, 7, 40739. doi: 10.1038/srep40739
  166. Zhang, R.; Yang, J.; Radford, D.C.; Fang, Y.; Kopeček, J. FRET Imaging of Enzyme-Responsive HPMA Copolymer Conjugate. Macromolecular Bioscience, 2017, 17(1), 1600125. doi: 10.1002/mabi.201600125
  167. Luo, W.; Wen, G.; Yang, L.; Tang, J.; Wang, J.; Wang, J.; Zhang, S.; Zhang, L.; Ma, F.; Xiao, L.; Wang, Y.; Li, Y. Dual-targeted and pH-sensitive Doxorubicin Prodrug-Microbubble Complex with Ultrasound for Tumor Treatment. Theranostics, 2017, 7(2), 452–465
  168. Zhao, Lei and Chen, Guojun and Li, Jun and Fu, Yingmei and Mavlyutov, Timur A. and Yao, Annie and Nickells, Robert W. and Gong, Shaoqin and Guo, Lian-Wang. An intraocular drug delivery system using targeted nanocarriers attenuates retinal ganglion cell degeneration. Journal of Controlled Release, 2017, 247, 153–166. doi: 10.1016/j.jconrel.2016.12.038
  169. Qu, S.; Shi, Y.; Benavides, S.; Hunter, A.J.; Gao, H.; Phillip, W.A. Copolymer Nanofilters with Charge-Patterned Domains for Enhanced Electrolyte Transport. Chemistry of Materials, 2017, 29(2), 762–772. doi: 10.1021/acs.chemmater.6b04660
  170. Hinde, E.; Thammasiraphop, K.; Duong, H.T.T.; Yeow, J.; Karagoz, B.; Boyer, C.; Gooding, J.J.; Gaus, K. Pair correlation microscopy reveals the role of nanoparticle shape in intracellular transport and site of drug release. Nature Nanotechnology, 2017, 12(1), 81–89. doi: 10.1038/nnano.2016.160
  171. Chen, K.; Guo, L.; Zhang, J.; Chen, Q.; Wang, K.; Li, C.; Li, W.; Qiao, M.; Zhao, X.; Hu, H.; Chen, D. A gene delivery system containing nuclear localization signal: increased nucleus import and transfection efficiency with the assistance of RanGAP1. Acta Biomaterialia, 2017, 48, 215–226. doi: 10.1016/j.actbio.2016.11.004
  172. O'Connell, C.L.; Nooney, R.; McDonagh, C. Cyanine5-doped silica nanoparticles as ultra-bright immunospecific labels for model circulating tumour cells in flow cytometry and microscopy. Biosensors and Bioelectronics, 2017, 91, 190–198. doi: 10.1016/j.bios.2016.12.023
  173. Sivak, L.; Subr, V.; Tomala, J.; Rihova, B.; Strohalm, J.; Etrych, T.; Kovar, M. Overcoming multidrug resistance via simultaneous delivery of cytostatic drug and P-glycoprotein inhibitor to cancer cells by HPMA copolymer conjugate. Biomaterials, 2017, 115, 65–80. doi: 10.1016/j.biomaterials.2016.11.013
  174. Braunová A.; Kostka, L.; Sivák, L.; Cuchalová, L.; Hvězdová, Z.; Laga, R.; Filippov, S.; Černoch, P.; Pechar, M.; Janoušková, O.; Šírová, M.; Etrych, T. Tumor-targeted micelle-forming block copolymers for overcoming of multidrug resistance. Journal of Controlled Release, 2017, 245, 41–51. doi: 10.1016/j.jconrel.2016.11.020
  175. Hu, J.; Chen, Y.; Li, Y.; Zhou, Z.; Cheng, Y. A thermo-degradable hydrogel with light-tunable degradation and drug release. Biomaterials, 2017, 112, 133–140. doi: 10.1016/j.biomaterials.2016.10.015
  176. Suarato, G.; Lee, S.-I.; Li, W.; Rao, S.; Khan, T.; Meng, Y.; Shelly, M. Micellar nanocomplexes for biomagnetic delivery of intracellular proteins to dictate axon formation during neuronal development. Biomaterials, 2017, 112, 176–191. doi: 10.1016/j.biomaterials.2016.09.035
  177. Yang, X.; Wang, Z.; Zhang, F.; Zhu, G.; Song, J.; Teng, G.-J.; Niu, G.; Chen, X. Mapping Sentinel Lymph Node Metastasis by Dual-probe Optical Imaging. Theranostics, 2017, 7(1), 153–163. doi: 10.7150/thno.17085
  178. Li, L.; Sun, W.; Li, L.; Liu, Y.; Wu, L.; Wang, F.; Zhou, Z.; Zhang, Z.; Huang, Y. A pH-responsive sequential-disassembly nanohybrid for mitochondrial targeting. Nanoscale, 2017, 9(1), 314–325. doi: 10.1039/c6nr07004c
  179. Wallat, J.D.; Czapar, A.E.; Wang, C.; Wen, A.M.; Wek, K.S.; Yu, X.; Steinmetz, N.F.; Pokorski, J.K. Optical and Magnetic Resonance Imaging Using Fluorous Colloidal Nanoparticles. Biomacromolecules, 2017, 18(1), 103–112. doi: 10.1021/acs.biomac.6b01389
  180. Shen, T.; Xu, X.; Guo, L.; Tang, H.; Diao, T.; Gan, Z.; Zhang, G.; Yu, Q. Efficient Tumor Accumulation, Penetration and Tumor Growth Inhibition Achieved by Polymer Therapeutics: The Effect of Polymer Architectures. Biomacromolecules, 2017, 18(1), 217–230. doi: 10.1021/acs.biomac.6b01533
  181. Sahle, F.F.; Giulbudagian, M.; Bergueiro, J.; Lademann, J.; Calderón, M. Dendritic polyglycerol and N-isopropylacrylamide based thermoresponsive nanogels as smart carriers for controlled delivery of drugs through the hair follicle. Nanoscale, 2017, 9(1), 172–182. doi: 10.1039/c6nr06435c
  182. Zhou, Y.; Li, W.; Wang, M.; Zhang, X.; Zhang, H.; Tong, X.; Xiao, Y. Competitive profiling of celastrol targets in human cervical cancer HeLa cells via quantitative chemical proteomics. Molecular BioSystems, 2017, 13(1), 83–91. doi: 10.1039/c6mb00691d
  183. Cho, W.; Koo, J.Y.; Park, Y.; Oh, K.; Lee, S.; Song, J.-S.; Bae, M.A.; Lim, D.; Lee, D.-S.; Park, S.B:. Treatment of Sepsis Pathogenesis with High Mobility Group Box Protein 1-Regulating Anti-inflammatory Agents. Journal of Medicinal Chemistry, 2017, 60(1), 170–179. doi: 10.1021/acs.jmedchem.6b00954
  184. Yang, Q.; Wu, L.; Li, L.; Zhou, Z.; Huang, Y. Subcellular co-delivery of two different site-oriented payloads for tumor therapy. Nanoscale, 2017, 9(4), 1547–1558. doi: 10.1039/c6nr08200a
  185. Shirure, V.S.; George, S.C. Design considerations to minimize the impact of drug absorption in polymer-based organ-on-a-chip platforms. Lab on a Chip, 2017, 17(4), 681–690. doi: 10.1039/c6lc01401a
  186. Bus, T.; Englert, C.; Reifarth, M.; Borchers, P.; Hartlieb, M.; Vollrath, A.; Hoeppener, S.; Traeger, A.; Schubert, U.S. 3rd generation poly(ethylene imine)s for gene delivery. Journal of Materials Chemistry B, 2017, 5(6), 1258–1274. doi: 10.1039/C6TB02592G
  187. Wang, H.; Wu, J.; Xu, L.; Xie, K.; Chen, C.; Dong, Y. Albumin Nanoparticle Encapsulation of Potent Cytotoxic Therapeutics Shows Sustained Drug Release and Alleviates Cancer Drug Toxicity. Chemical Communications, 2017, 53(17), 2618–2621. doi: 10.1039/c6cc08978j
  188. Lu, K.-Y.; Li, R.; Hsu, C.-H.; Lin, C.-W.; Chou, S.-C.; Tsai, M.-L.; Mi, F.-L. Development of a new type of multifunctional fucoidan-based nanoparticles for anticancer drug delivery. Carbohydrate Polymers, 2017, 165, 410–420. doi: 10.1016/j.carbpol.2017.02.065
  189. Cheng, L.; Ji, K.; Shih, T. Y.; Haddad, A.; Giatsidis, G.; Mooney, D.J.; Orgill, D.P.; Nabzdyk, C.S. Injectable Shape-Memorizing Three-Dimensional Hyaluronic Acid Cryogels for Skin Sculpting and Soft Tissue Reconstruction. Tissue Engineering Part A, 2017, 23(5–6), 243–251. doi: 10.1089/ten.tea.2016.0263
  190. Kilic, E.; Novoselova, M.V.; Lim, S.H.; Pyataev, N.A.; Pinyaev, S.I.; Kulikov, O.A.; Sindeeva, O.A.; Mayorova, O.A.; Murney, R.; Antipina, M.N.; Haigh, B.; Sukhorukov, G.B.; Kiryukhin, M.V. Formulation for Oral Delivery of Lactoferrin Based on Bovine Serum Albumin and Tannic Acid Multilayer Microcapsules. Scientific Reports, 2017, 7, 44159. doi: 10.1038/srep44159
  191. Musiol-Kroll, E.M.; Zubeil, F.; Schafhauser, T.; Härtner, T.; Kulik, A.; McArthur, J.B.; Koryakina, I.; Wohlleben, W.; Grond, S.; Williams, G.J.; Lee, S.Y.; Weber, T. Polyketide bio-derivatization using the promiscuous acyltransferase KirCII. ACS Synthetic Biology, 2017, 6(3), 421–427. doi: 10.1021/acssynbio.6b00341
  192. Shi, F.; Li, M.; Wu, S.; Yang, F.; Di, W.; Pan, M.; Zhao, F.; Luo, S.; Gu, N.; Dou, J. Enhancing the Anti-Multiple Myeloma Efficiency in a Cancer Stem Cell Xenograft Model by Conjugating the ABCG2 Antibody with Microbubbles for a Targeted Delivery of Ultrasound Mediated Epirubicin. Biochemical Pharmacology, 2017, 132, 18–28. doi: 10.1016/j.bcp.2017.02.014
  193. Taneja, N.; Zofall, M.; Balachandran, V.; Thillainadesan, G.; Sugiyama, T.; Wheeler, D.; Zhou, M.; Grewal, S.I.S. SNF2 Family Protein Fft3 Suppresses Nucleosome Turnover to Promote Epigenetic Inheritance and Proper Replication. Molecular Cell, 2017, 66(1), 50–62. doi: 10.1016/j.molcel.2017.02.006
  194. Lin, S.; Shah, A.; Hernández-Gil, J.; Stanziola, A.; Harriss, B.I.; Matsunaga, T.O.; Long, N.; Bamber, J.; Tang, M.-X. Optically and acoustically triggerable sub-micron phase-change contrast agents for enhanced photoacoustic and ultrasound imaging. Photoacoustics, 2017, 6, 26–36. doi: 10.1016/j.pacs.2017.04.001
  195. Kaux JF, Libertiaux V, Leprince P, Fillet M, Denoel V Wyss C, Lecut C, Gothot A, Le Goff C, Croisier JL, Crielaard JM, Drion P. Eccentric Training for Tendon Healing After Acute Lesion: A Rat Model. The American Journal of Sports Medicine, 2017, 45(6), 1440–1446. doi: 10.1177/0363546517689872
  196. Lunde, N.N.; Haugen, M.H.; Larsen, K.B.B.; Damgaard, I.; Pettersen, S.J.; Kasem, R.; Rut, W.; Drag, M.; Poreba, M.; Johansen, Harald T.; Solberg, R. Glycosylation is important for legumain localization and processing to active forms but not for cystatin E/M inhibitory functions. Biochimie, 2017, 139, 27–37. doi: 10.1016/j.biochi.2017.05.009
  197. Schlegel, I.; Muñoz-Espí, R.; Renz, P.; Lieberwirth, I.; Floudas, G.; Suzuki, Y.; Crespy, D.; Landfester, K. Crystallinity Tunes Permeability of Polymer Nanocapsules. Macromolecules, 2017, 50(12), 4725–4732. doi: 10.1021/acs.macromol.7b00667
  198. Shalgunov, V.; Zaytseva-Zotova, D.; Zinchenko, A.; Levada, T.; Shilov, Y.; Andreyev, D.; Dzhumashev, D.; Metelkin, E.; Urusova, A.; Demin, O.; McDonnell, K.; Troiano, G.; Zale, S.; Safarovа, E. Comprehensive study of the drug delivery properties of poly(L-lactide)-poly(ethylene glycol) nanoparticles in rats and tumor-bearing mice. Journal of Controlled Release, 2017, 261, 31–42. doi: 10.1016/j.jconrel.2017.06.006
  199. Maity, S.; Viazovkina, E.; Gall, A.; Lyubchenko, Y.L. Single-molecule probing of amyloid nano-ensembles using the polymer nanoarray approach. Physical Chemistry Chemical Physics, 2017, 19(25), 16387–16394. doi: 10.1039/c7cp02691a
  200. Nakhaei, E.; Kim, C.W.; Funamoto, D.; Sato, H.; Nakamura, Y.; Kishimura, A.; Mori, T.; Katayama, Y. Design of a ligand for cancer imaging with long blood circulation and an enhanced accumulation ability in tumors. MedChemComm, 2017, 8(6), 1190–1195. doi: 10.1039/c7md00102a
  201. Beldman, T.J.; Senders, M.L.; Alaarg, A.; Perez-Medina, C.; Tang, J.; Zhao, Y.; Fay, F.; Deichmöller, J.; Born, B.; Desclos, E.; van der Wel, N.N.; Hoebe, R.A.; Kohen, F.; Kartvelishvily, E.; Neeman, M.; Reiner, T.; Calcagno, C.; Fayad, Z.A.; de Winther, M.P.J.; Lutgens, E.; Mulder, W.J.M.; Kluza, E. Hyaluronan Nanoparticles Selectively Target Plaque-Associated Macrophages and Improve Plaque Stability in Atherosclerosis. ACS Nano, 2017, 11(6), 5785–5799. doi: 10.1021/acsnano.7b01385
  202. Luthman, A.S.; Dumitru, S.; Quiros-Gonzalez, I.; Joseph, J.; Bohndiek, S.E. Fluorescence hyperspectral imaging (fHSI) using a spectrally resolved detector array. Journal of Biophotonics, 2017, 10(6–7), 840–853. doi: 10.1002/jbio.201600304
  203. Massey, M.; Kim, H.; Conroy, E.M.; Algar, W.R. Expanded Quantum Dot-Based Concentric Förster Resonance Energy Transfer: Adding and Characterizing Energy-Transfer Pathways for Triply Multiplexed Biosensing. The Journal of Physical Chemistry C, 2017, 121(24), 13345–13356. doi: 10.1021/acs.jpcc.7b02739
  204. Zhao, T.; Li, T.; Liu, Y. Silver nanoparticle plasmonic enhanced förster resonance energy transfer (FRET) imaging of protein-specific sialylation on the cell surface. Nanoscale, 2017, 9(28), 9841–9847. doi: 10.1039/c7nr01562c
  205. Warminski, M.; Sikorski, P.J.; Warminska, Z.; Lukaszewicz, M.; Kropiwnicka, A.; Zuberek, J.; Darzynkiewicz, E.; Kowalska, J.; Jemielity, J. Amino-functionalized 5' cap analogs as tools for site-specific sequence-independent labeling of messenger RNA. Bioconjugate Chemistry, 2017, 28(7), 1978–1992. doi: 10.1021/acs.bioconjchem.7b00291
  206. Garg, S.M.; Paiva, I.M.; Vakili, M.R.; Soudy, R.; Agopsowicz, K.; Soleimani, A.; Hitt, M.; Kaur, K.; Lavasanifar, A. Traceable PEO-poly(ester) micelles for breast cancer targeting: The effect of core structure and targeting peptide on micellar tumor accumulation. Biomaterials, 2017, 144, 17–29. doi: 10.1016/j.biomaterials.2017.08.001
  207. Zhou, Z.; Liu, Y.; Wu, L.; Li, L.; Huang, Y. Enhanced nuclear delivery of anti-cancer drugs using micelles containing releasable membrane fusion peptide and nuclear-targeting retinoic acid. Journal of Materials Chemistry B, 2017, 5(34), 7175–7185. doi: 10.1039/C7TB01177F
  208. Drexel, M.; Romanov, R.A.; Wood, J.; Weger, S.; Heilbronn, R.; Wulff, P.; Tasan, R.O.; Harkany, T.; Sperk, G. Selective silencing of hippocampal parvalbumin interneurons induces development of recurrent spontaneous limbic seizures in mice. Journal of Neuroscience, 2017, 37(34), 8166–8179. doi: 10.1523/jneurosci.3456-16.2017
  209. Stefanello, T.; Couturaud, B.; Szarpak, A.; Fournier, D.; Louage, B.; Garcia, F.; Vataru Nakamura, C.; De Geest, B.; Woisel, P.; van der Sanden, B.; Auzely, R. Coumarin-containing thermoresponsive hyaluronic acid-based nanogels as delivery systems for anticancer chemotherapy. Nanoscale, 2017, 9(33), 12150–12162. doi: 10.1039/C7NR03964F
  210. Long, M.J.; Lin, H.-Y.; Parvez, S.; Zhao, Y.; Poganik, J.R.; Huang, P.; Aye, Y. β-TrCP1 Is a Vacillatory Regulator of Wnt Signaling. Cell Chemical Biology, 2017, 24(8), 944–957.e7. doi: 10.1016/j.chembiol.2017.06.009
  211. Westergaard Mulberg, M.; Taskova, M.; Thomsen, R.P.; Okholm, A.H.; Kjems, J.; Astakhova, K. New Fluorescent Nanoparticles for Ultrasensitive Detection of Nucleic Acids by Optical Methods. Chembiochem, 2017, 18(16), 1599–1603. doi: 10.1002/cbic.201700125
  212. Louage, B.; Tack, L.; Wang, Y.; De Geest, B.G. Poly(glycerol sebacate) nanoparticles for encapsulation of hydrophobic anti-cancer drugs. Polymer Chemistry, 2017, 8(34), 5033–5038. doi: 10.1039/c6py02192a
  213. Poh, S.; Putt, K.S.; Low, P.S. Folate-targeted dendrimers selectively accumulate at sites of inflammation in mouse models of ulcerative colitis and atherosclerosis. Biomacromolecules, 2017, 18(10), 3082–3088. doi: 10.1021/acs.biomac.7b00728
  214. Zhao, Y.; Houston, Z.H.; Simpson, J.D.; Chen, L.; Fletcher, N.L.; Fuchs, A.V.; Blakey, I.; Thurecht, K.J. Using Peptide Aptamer Targeted Polymers as a Model Nanomedicine for Investigating Drug Distribution in Cancer Nanotheranostics. Molecular Pharmaceutics, 2017, 14(10), 3539–3549. doi: 10.1021/acs.molpharmaceut.7b00560
  215. Qiu, Y.; Levendosky, R.F.; Chakravarthy, S.; Patel, A.; Bowman, G.D.; Myong, S. The Chd1 Chromatin Remodeler Shifts Nucleosomal DNA Bidirectionally as a Monomer. Molecular Cell, 2017, 68(1), 76–88.e6. doi: 10.1016/j.molcel.2017.08.018
  216. Yang, W.; Xia, Y.; Zou, Y.; Meng, F.; Zhang, J.; Zhong, Z. Bioresponsive Chimaeric Nano-polymersomes Enable Targeted and Efficacious Protein Therapy for Human Lung Cancers in Vivo. Chemistry of Materials, 2017, 29(20), 8757–8765. doi: 10.1021/acs.chemmater.7b02953
  217. Gilbert, T.; Alsop, R.J.; Babi, M.; Moran-Mirabal, J.; Rheinstadter, M.C.; Hoare, T. Nanostructure of Fully Injectable Hydrazone-Thiosuccinimide Interpenetrating Polymer Network Hydrogels Assessed by Small-Angle Neutron Scattering and dSTORM Single-Molecule Fluorescence Microscopy. ACS Applied Materials & Interfaces, 2017, 9(48), 42179–42191. doi: 10.1021/acsami.7b11637
  218. Lin, T.-H.; Lin, C.-H.; Liu, Y.-J.; Huang, C.Y.; Lin, Y.-C.; Wang, S.-K. Controlling Ligand Spacing on Surface: Polyproline-Based Fluorous Microarray as a Tool in Spatial Specificity Analysis and Inhibitor Development for Carbohydrate-Protein Interactions. ACS Applied Materials & Interfaces, 2017, 9(48), 41691–41699. doi: 10.1021/acsami.7b13200
  219. Masarapu, H.; Patel, B.K.; Chariou, P.L.; Hu, H.; Gulati, N.M.; Carpenter, B.L.; Ghiladi, R.A.; Shukla, S.; Steinmetz, N.F. Physalis Mottle Virus-Like Particles as Nanocarriers for Imaging Reagents and Drugs. Biomacromolecules, 2017, 18(12), 4141–4153. doi: 10.1021/acs.biomac.7b01196
  220. Butler, C.R.; Beck, E.M.; Harris, A.R.; Huang, Z.; McAllister, L.A.; Am Ende, C.W.; Fennell, K.F.; Foley, T.L.; Fonseca, K.R.; Hawrylik, S.J.; Johnson, D.S.; Knafels, J.D.; Mente, S.; Noell, S.; Pandit, J.; Phillips, T.B.; Piro, J.R.; Rogers, B.N.; Samad, T.A.; Wang, J.; Wan, S.; Brodney, M.A. Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase. Journal of Medicinal Chemistry, 2017, 60(23), 9860–9873. doi: 10.1021/acs.jmedchem.7b01531
  221. Cao, T.; Zhou, X.; Zheng, Y.; Sun, Y.; Zhang, J.; Chen, W.; Zhang, J.; Zhou, Z.; Yang, S.-P.; Zhang, Y.; Yang, H.; Wang, M.-W. Chelator-Free Conjugation of 99mTc and Gd3+ to PEGylated Nanographene Oxide for Dual-modality SPECT/MR Imaging of Lymph Nodes. ACS Applied Materials & Interfaces, 2017, 9(49), 42612–42621. doi: 10.1021/acsami.7b14836
  222. Barsh, G.R.; Isabella, A.J.; Moens, C.B. Vagus Motor Neuron Topographic Map Determined by Parallel Mechanisms of hox5 Expression and Time of Axon Initiation. Current Biology, 2017, 27(24), 3812–3825.e3. doi: 10.1016/j.cub.2017.11.022
  223. Wei, L.; Chen, Z.; Shi, L.; Long, R.; Anzalone, A.V.; Zhang, L.; Hu, F.; Yuste, R.; Cornish, V.W.; Min, W. Super-multiplex vibrational imaging. Nature, 2017, 544(7651), 465-470. doi: 10.1038/nature22051
  224. Peng, H.; Jin, H.; Zhuo, H.; Huang, H. Enhanced antitumor efficacy of cisplatin for treating ovarian cancer in vitro and in vivo via transferrin binding. Oncotarget, 2017, 8(28), 45597-45611. doi: 10.18632/oncotarget.17316
  225. Han, Z.; Wu, X.; Roelle, S.; Chen, C.; Schiemann, W.P.; Lu, Z.-R. Targeted gadofullerene for sensitive magnetic resonance imaging and risk-stratification of breast cancer. Nature Communications, 2017, 8, 692. doi: 10.1038/s41467-017-00741-y
  226. Luo, W.; Wen, G.; Yang, L.; Tang, J.; Wang, J.; Wang, J.; Zhang, S.; Zhang, L.; Ma, F.; Xiao, L.; Wang, Y.; Li, Y. Dual-targeted and pH-sensitive Doxorubicin Prodrug-Microbubble Complex with Ultrasound for Tumor Treatment. Theranostics, 2017, 7(2), 452-465. doi: 10.7150/thno.16677

2016

  1. Löschmann, N.; Michaelis, M.; Rothweiler, F.; Voges, Y.; Balónová, B.; Blight, B.A.; Cinatl, J. ABCB1 as predominant resistance mechanism in cells with acquired SNS-032 resistance. Oncotarget, 2016, 7(36), 58051–58064. doi: 10.18632/oncotarget.11160
  2. Korkmaz, E.; Friedrich, E.E.; Ramadan, M.H.; Erdos, G.; Mathers, A.R.; Ozdoganlar, O.B.; Washburn, N.R.; Falo, Jr, L.D. Tip-Loaded Dissolvable Microneedle Arrays Effectively Deliver Polymer-Conjugated Antibody Inhibitors of Tumor-Necrosis-Factor-Alpha Into Human Skin. Journal of Pharmaceutical Sciences, 2016, 105(11), 3453–3457. doi: 10.1016/j.xphs.2016.07.008
  3. Jackson, A.; Jani, S.; Sala, C.D.; Soler-Bistué, A.J.C.; Zorreguieta, A.; Tolmasky, M.E. Assessment of configurations and chemistries of bridged nucleic acids-containing oligomers as external guide sequences: a methodology for inhibition of expression of antibiotic resistance genes. Biology Methods and Protocols, 2016, 1(1), bpw001. doi: 10.1093/biomethods/bpw001
  4. Yoshimura, T.; Kurogi, K.; Liu, M.-C.; Suiko, M.; Sakakibara, Y. A proteomic approach for the analysis of S-nitrosylated proteins using a fluorescence labeling technique. Journal of Electrophoresis, 2016, 60(1), 5–14. doi: 10.2198/jelectroph.60.5
  5. Rudnick-Glick, S.; Corem-Salkmon, E.; Grinberg, I.; Margel, S. Targeted drug delivery of near IR fluorescent doxorubicin-conjugated poly(ethylene glycol) bisphosphonate nanoparticles for diagnosis and therapy of primary and metastatic bone cancer in a mouse model. Journal of Nanobiotechnology, 2016, 14, 80. doi: 10.1186/s12951-016-0233-6
  6. Mendler, C.T.; Feuchtinger, A.; Heid, I.; Aichler, M.; D'Alessandria, C.; Pirsig, S.; Blechert, B.; Wester, H.-J.; Braren, R.; Walch, A.; Skerra, A.; Schwaiger, M. Tumor uptake of anti-CD20 Fabs depends on tumor perfusion. Journal of Nuclear Medicine, 2016, 57(12), 1971–1977. doi: 10.2967/jnumed.116.176784
  7. Nemethova, M.; Talian, I.; Danielisova, V.; Tkacikova, S.; Bonova, P.; Bober, P.; Matiasova, M.; Sabo, J.; Burda, J. Delayed bradykinin postconditioning modulates intrinsic neuroprotective enzyme expression in the rat CA1 region after cerebral ischemia: a proteomic study. Metabolic Brain Disease, 2016, 31(6), 1391–1403. doi: 10.1007/s11011-016-9859-1
  8. Li, Y.; Zhao, Q.; Wang, Y.; Man, T.; Zhou, L.; Fang, X.; Pei, H.; Chi, L.; Liu, J. Ultrasensitive Signal-on Detection of Nucleic Acids with Surface-Enhanced Raman Scattering and Exonuclease III Assisted Probe Amplification. Analytical Chemistry, 2016, 88(23), 11684–11690. doi: 10.1021/acs.analchem.6b03267
  9. Wu, Z.-G.; Jiang, W.; Chen, S.-L.; Mantri, N.; Tao, Z.-M.; Jiang, C.-X. Insights from the Cold Transcriptome and Metabolome of Dendrobium officinale: Global Reprogramming of Metabolic and Gene Regulation Networks during Cold Acclimation. Frontiers in Plant Science, 2016, 7, 1653. doi: 10.3389/fpls.2016.01653
  10. Zhang, X.; MIn, L.; Jia, C. Application of Wavelet Transform Algorithm and Rolling Ball Algorithm in Single Molecule Fluorescence Resonance Energy Transfer Images. Progress in Biochemistry and Biophysics, 2016, 43(10), 997–1003. doi: 10.16476/j.pibb.2016.0218
  11. Ruhl, K.E; Rovis, T. Visible Light-Gated Cobalt Catalysis for a Spatially and Temporally Resolved [2+2+2] Cycloaddition. Journal of the American Chemical Society, 2016, 138(48), 15527–15530. doi: 10.1021/jacs.6b08792
  12. Koziolová, E.; Machová, D.; Pola, R.; Janoušková, O.; Chytil, P.; Laga, R.; Filippov, S.K.; Šubr, V.; Etrych, T.; Pechar, M. Micelle-forming HPMA copolymer conjugates of ritonavir bound via a pH-sensitive spacer with improved cellular uptake designed for enhanced tumor accumulation. Journal of Materials Chemistry B, 2016, 4(47), 7620–7629. doi: 10.1039/C6TB02225A
  13. Zhou, L.; Wang, K.; Wu, Z.; Dong, H.; Sun, H.; Cheng, X.; Zhang, H.; Zhou, H.; Jia, C.; Jin, Q.; Mao, H.; Coll, J.-L.; Zhao, J. Investigation of Controllable Nanoscale Heat-Denatured Bovine Serum Albumin Films on Graphene. Langmuir, 2016, 32(48), 12623–12631. doi: 10.1021/acs.langmuir.6b03296
  14. Xu, X.; Xu, Z.; Liu, J.; Zhang, Z.; Chen, H.; Li, X.; Shi, S. Visual tracing of diffusion and biodistribution for amphiphilic cationic nanoparticles using photoacoustic imaging after ex vivo intravitreal injections. International Journal of Nanomedicine, 2016, 11, 5079–5086. doi: 10.2147/IJN.S109986
  15. Yan, Y.; Liu, L.; Xiong, H.; Miller, J.B.; Zhou, K.; Kos, P.; Huffman, K.E.; Elkassih, S.; Norman, J.W.; Carstens, R.; Kim, J.; Minna, J.D.; Siegwart, D.J. Functional polyesters enable selective siRNA delivery to lung cancer over matched normal cells. Proceedings of the National Academy of Sciences of the U.S.A., 2016, 113(39), E5702–E5710. doi: 10.1073/pnas.1606886113
  16. Xue, C.; Whitis, N.R.; Sashital, D.G. Conformational Control of Cascade Interference and Priming Activities in CRISPR Immunity. Molecular Cell, 2016, 64(4), 826–834. doi: 10.1016/j.molcel.2016.09.033
  17. Duan, X.; Li, H.; Zhou, J.; Zhou, Q.; Oldham, K.R.; Wang, T.D. Visualizing epithelial expression of EGFR in vivo with distal scanning side-viewing confocal endomicroscope. Scientific Reports, 2016, 6, 37315. doi: 10.1038/srep37315
  18. Cheng, J.; Feng, S.; Han, S.; Zhang, X.; Chen, Y.; Zhou, X.; Wang, R.; Li, X.; Hu, H.; Zhang, J. Facile Assembly of Cost-Effective and Locally Applicable or Injectable Nanohemostats for Hemorrhage Control. ACS Nano, 2016, 10(11), 9957&ndash9973. doi: 10.1021/acsnano.6b04124
  19. Allen, C.D.; Chen, M.Y.; Trick, A.Y.; Le, D.T.; Ferguson, A.L.; Link, A.J. Thermal Unthreading of the Lasso Peptides Astexin-2 and Astexin-3. ACS Chemical Biology, 2016, 11(11), 3043–3051. doi: 10.1021/acschembio.6b00588
  20. Ye, R.; Zhu, C.; Song, Y.; Song, J.; Fu, S.; Lu, Q.; Yang, X.; Zhu, M.-J.; Du, D.; Li, H.; Lin, Y. One-pot bioinspired synthesis of all-inclusive protein–protein nanoflowers for point-of-care bioassay: detection of E. coli O157:H7 from milk. Nanoscale, 2016, 8(45), 18980–18986. doi: 10.1039/c6nr06870g
  21. Mattheolabakis, G.; Ling, D.; Ahmad, G.; Amiji, M. Enhanced Anti-Tumor Efficacy of Lipid-Modified Platinum Derivatives in Combination with Survivin Silencing siRNA in Resistant Non-Small Cell Lung Cancer. Pharmaceutical Research, 2016, 33(12), 2943–2953. doi: 10.1007/s11095-016-2016-z
  22. Cai, Lei and Dewi, Ruby E. and Goldstone, Andrew B. and Cohen, Jeffrey E. and Steele, Amanda N. and Woo, Y. Joseph and Heilshorn, Sarah C. Regulating Stem Cell Secretome Using Injectable Hydrogels with In Situ Network Formation. Advanced Healthcare Materials, 2016, 5(21), 2758–2764. doi: 10.1002/adhm.201600497
  23. Nemudraya, A.; Kuligina, E.; Ilyichev, A.; Fomin, A.; Stepanov, G.; Savelyeva, A.; Koval, O.; Richter, V. Selection of antitumor displayed peptides for the specific delivery of the anticancer drug lactaptin. Oncology Letters, 2016, 12(6), 4547–4555. doi: 10.3892/ol.2016.5266
  24. Parvez, S.; Long, M.J.C.; Lin, H.-Y.; Zhao, Y.; Haegele, J.A.; Pham, V.N.; Lee, D.K.; Aye, Y. T-REX on-demand redox targeting in live cells. Nature Protocols, 2016, 11(12), 2328–2356. doi: 10.1038/nprot.2016.114
  25. Berte, N.; Piee-Staffa, A.; Piecha, N.; Wang, M.; Borgmann, K.; Kaina, B.; Nikolova, T. Targeting homologous recombination by pharmacological inhibitors enhances the killing response of glioblastoma cells treated with alkylating drugs. Molecular Cancer Therapeutics, 2016, 15(11), 2665–2678. doi: 10.1158/1535-7163.mct-16-0176
  26. Hill, T.K.; Kelkar, S.S.; Wojtynek, N.E.; Souchek, J.J:; Payne, W.M.; Stumpf, K.; Marini, F.C.; Mohs, A.M. Near Infrared Fluorescent Nanoparticles Derived from Hyaluronic Acid Improve Tumor Contrast for Image-Guided Surgery. Theranostics, 2016, 6(13), 2314–2328. doi: 10.7150/thno.16514
  27. Cao, T.; You, P.; Zhou, X.; Luo, J.; Xu, X.; Zhou, Z.; Yang, S.; Zhang, Y.; Yang, H.; Wang, M. Visualization of size-dependent tumour retention of PEGylated nanographene oxide via SPECT imaging. Journal of Materials Chemistry B, 2016, 4(39), 6446–6453. doi: 10.1039/c6tb01892k
  28. Machulkin, A.E.; Garanina, A.S.; Zhironkina, O.A.; Beloglazkina, E.K.; Zyk, N.V.; Savchenko, A.G.; Kotelyanskii, V.E.; Mazhuga, A.G. Nanohybride Materials Based on Magnetite-Gold Nanoparticles for Diagnostics of Prostate Cancer: Synthesis and In Vitro Testing. Bulletin of Experimental Biology and Medicine, 2016, 161(5), 706–710. doi: 10.1007/s10517-016-3490-3
  29. Chen, W.; Wang, F.; Zhang, X.; Hu, J.; Wang, X.; Yang, K.; Huang, L.; Xu, M.; Li, Q.; Fu, L. Overcoming ABCG2-mediated multidrug resistance by a mineralized hyaluronan-drug nanocomplex. Journal of Materials Chemistry B, 2016, 4(41), 6652–6661. doi: 10.1039/c6tb01545j
  30. Zuhl, A.M.; Nolan, C.E.; Brodney, M.A.; Niessen, S.; Atchison, K.; Houle, C.; Karanian, D.A.; Ambroise, Cl.; Brulet, J.W.; Beck, E.M.; Doran, S.D.; O'Neill, B.T.; am Ende, C.W.; Chang, C.; Geoghegan, K.F.; West, G.M.; Judkins, J.C.; Hou, X.; Riddell, D.R.; Johnson, D.S. Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of β-secretase inhibitors. Nature communications, 2016, 7, 13042. doi: 10.1038/ncomms13042
  31. Pombo-García, K.; Weiss, S.; Zarschler, K.; Ang, C.-S.; Hübner, R.; Pufe, J.; Meister, S.; Seidel, J.; Pietzsch, J.; Spiccia, L.; Stephan, H.; Graham, B. Zwitterionic polymer-coated ultrasmall superparamagnetic iron oxide nanoparticles with low protein interaction and high biocompatibility. ChemNanoMat, 2016, 2(10), 959–971. doi: 10.1002/cnma.201600233
  32. Shi, P.; Ju, E.; Yan, Z.; Gao, N.; Wang, J.; Hou, J.; Zhang, Y.; Ren, J.; Qu, X. Spatiotemporal control of cell-cell reversible interactions using molecular engineering. Nature communications, 2016, 7, 13088. doi: 10.1038/ncomms13088
  33. Zhou, Q.; Li, Z.; Zhou, J.; Joshi, B.P.; Li, G.; Duan, X.; Kuick, R.; Owens, S.R.; Wang, T.D. In vivo photoacoustic tomography of EGFR overexpressed in hepatocellular carcinoma mouse xenograft. Photoacoustics, 2016, 4(2), 43–54. doi: 10.1016/j.pacs.2016.04.001
  34. Mann, S.K.; Dufour, A.; Glass, J.J.; De Rose, R.; Kent, S.J.; Such, G.K.; Johnston, A.P.R. Tuning the properties of pH responsive nanoparticles to control cellular interactions in vitro and ex vivo. Polymer Chemistry, 2016, 7(38), 6015–6024. doi: 10.1039/c6py01332e
  35. Ye, Y.; Wang, J.; Hu, Q.; Hochu, G.M.; Xin, H.; Wang, C.; Gu, Z. Synergistic Transcutaneous Immunotherapy Enhances Antitumor Immune Responses through Delivery of Checkpoint Inhibitors. ACS Nano, 2016, 10(9), 8956–8963. doi: 10.1021/acsnano.6b04989
  36. Gera, L.; Charest-Morin, X.; Jean, M.; Bachelard, H.; Marceau, F. Infrared-emitting, peptidase-resistant fluorescent ligands of the bradykinin B2 receptor: application to cytofluorometry and imaging. BMC Research Notes, 2016, 9, 452. doi: 10.1186/s13104-016-2258-1
  37. Smith, A.A.A.; Zuwala, K.; Pilgram, O.; Johansen, K.S.; Tolstrup, M.; Dagnæs-Hansen, F.; Zelikin, A.N. Albumin-Polymer-Drug Conjugates: Long Circulating, High Payload Drug Delivery Vehicles. ACS Macro Letters, 2016, 5, 1089–1094. doi: 10.1021/acsmacrolett.6b00544
  38. Zhao, L.; Ma, S.; Pan, Y.; Zhang, Q.; Wang, K.; Song, D.; Wang, X.; Feng, G.; Liu, R.; Xu, H.; Zhang, J.; Qiao, M.; Kong, D. Functional Modification of Fibrous PCL Scaffolds with Fusion Protein VEGF-HGFI Enhanced Cellularization and Vascularization. Advanced Healthcare Materials, 2016, 5(18), 2376–2385. doi: 10.1002/adhm.201600226
  39. Xiao, F.; Li, G.; Wu, Y.; Chen, Q.; Wu, Z.; Yu, R. Label-Free Photonic Crystal-Based β-Lactamase Biosensor for β-Lactam Antibiotic and β-Lactamase Inhibitor. Analytical Chemistry, 2016, 88(18), 9207–9212. doi: 10.1021/acs.analchem.6b02457
  40. Sui, B.; Zhong, G.; Sun, J. Drug-loadable Mesoporous Bioactive Glass Nanospheres: Biodistribution, Clearance, BRL Cellular Location and Systemic Risk Assessment via 45Ca Labelling and Histological Analysis. Scientific Reports, 2016, 6, 33443. doi: 10.1038/srep33443
  41. Fiacco, S.V.; Kelderhouse, L.E.; Hardy, A.; Peleg, Y.; Hu, B.; Ornelas, A.; Yang, P.; Gammon, S.T.; Howell, S.M.; Wang, P.; Takahashi, T.T.; Millward, S.W.; Roberts, R.W. Directed Evolution of Scanning Unnatural-Protease-Resistant (SUPR) Peptides for in Vivo Applications. Chembiochem, 2016, 17(17), 1643–1651. doi: 10.1002/cbic.201600253
  42. Liu, M.; Richardson, R.R.; Mountford, S.J.; Zhang, L.; Tempone, M.H.; Herzog, H.; Holliday, N.D.; Thompson, P.E. Identification of a Cyanine-Dye Labelled Peptidic Ligand for Y1R and Y4R, based upon the Neuropeptide Y C-terminal analogue, BVD-15. Bioconjugate Chemistry, 2016, 27(9), 2166–2175. doi: 10.1021/acs.bioconjchem.6b00376
  43. Ramirez, Lisa and Herschkowitz, Jason I. and Wang, Jun. Stand-Sit Microchip for High-Throughput, Multiplexed Analysis of Single Cancer Cells. Scientific Reports, 2016, 6, 32505. doi: 10.1038/srep32505
  44. Liu, S.; Dozois, M.D.; Chang, C.N.; Ahmad, A.; Ng, D.L.T.; Hileeto, D.; Liang, H.; Reyad, M.-M.; Boyd, S.; Jones, L.W.; Gu, F.X. Prolonged Ocular Retention of Mucoadhesive Nanoparticle Eye Drop Formulation Enables Treatment of Eye Diseases Using Significantly Reduced Dosage. Molecular Pharmaceutics, 2016, 13(9), 2897–2905. doi: 10.1021/acs.molpharmaceut.6b00445
  45. Mann, S.K.; Czuba, E.; Selby, L.I.; Such, G.K.; Johnston, A.P.R. Quantifying Nanoparticle Internalization Using a High Throughput Internalization Assay. Pharmaceutical Research, 2016, 33(10), 2421–2432. doi: 10.1007/s11095-016-1984-3
  46. Hong, W.; Lee, S.; Chang, H.J.; Lee, E.S.; Cho, Y. Multifunctional magnetic nanowires: A novel breakthrough for ultrasensitive detection and isolation of rare cancer cells from non-metastatic early breast cancer patients using small volumes of blood. Biomaterials, 2016, 106, 78–86. doi: 10.1016/j.biomaterials.2016.08.020
  47. Chen, Y.; Li, Y.; Shen, W.; Li, K.; Yu, L.; Chen, Q.; Ding, J. Controlled release of liraglutide using thermogelling polymers in treatment of diabetes. Scientific Reports, 2016, 6, 31593. doi: 10.1038/srep31593
  48. Kollarigowda, R.H.; De Santo, I.; Rianna, C.; Fedele, C.; Manikas, A.C.; Cavalli, S.; Netti, P.A. Shedding light on azopolymer brush dynamics by fluorescence correlation spectroscopy. Soft Matter, 2016, 12(34), 7102–7111. doi: 10.1039/c6sm01482h
  49. Sun, Y.; Hong, S.; Ma, X.; Cheng, K.; Wang, J.; Zhang, Z.; Yang, M.; Jiang, Y.; Hong, X.; Cheng, Z. Recyclable Cu(I)/Melanin Dots for Cycloadditions, Bioconjugation and Cell Labeling. Chemical Science, 2016, 7(9), 5888–5892. doi: 10.1039/c6sc01536k
  50. Zhang, Q.; Tao, H.; Lin, Y.; Hu, Y.; An, H.; Zhang, D.; Feng, S.; Hu, H.; Wang, R.; Li, X.; Zhang, J. A superoxide dismutase/catalase mimetic nanomedicine for targeted therapy of inflammatory bowel disease. Biomaterials, 2016, 105, 206–221. doi: 10.1016/j.biomaterials.2016.08.010
  51. Feng, S.; Hu, Y.; Peng, S.; Han, S.; Tao, H.; Zhang, Q.; Xu, X.; Zhang, J.; Hu, H. Nanoparticles responsive to the inflammatory microenvironment for targeted treatment of arterial restenosis. Biomaterials, 2016, 105, 167–184. doi: 10.1016/j.biomaterials.2016.08.003
  52. Spears, B.R.; Marin, M.A.; Chaker, A.N.; Lampley, M.W.; Harth, E. Precise Microscale Polymeric Networks through Piezoelectronic Inkjet Printing. ACS Biomaterials Science & Engineering, 2016, 2(8), 1265–1272. doi: 10.1021/acsbiomaterials.6b00175
  53. Su, S.; Wang, J.; Vargas, E.; Wei, J.; Martinez-Zaguilan, R.; Sennoune, S.R.; Pantoya, M.L.; Wang, S.; Chaudhuri, J.; Qiu, J. Porphyrin Immobilized Nano-Graphene Oxide for Enhanced and Targeted Photothermal Therapy of Brain Cancer. ACS Biomaterials Science & Engineering, 2016, 2(8), 1357–1366. doi: 10.1021/acsbiomaterials.6b00290
  54. Li, Hong-Jun and Du, Jin-Zhi and Liu, Jing and Du, Xiao-Jiao and Shen, Song and Zhu, Yan-Hua and Wang, Xiaoyan and Ye, Xiaodong and Nie, Shuming and Wang, Jun. Smart Superstructures with Ultrahigh pH-Sensitivity for Targeting Acidic Tumor Microenvironment: Instantaneous Size Switching and Improved Tumor Penetration. ACS Nano, 2016, 10(7), 6753–6761. doi: 10.1021/acsnano.6b02326
  55. Jiang, X.; Bugno, J.; Hu, C.; Yang, Y.; Herold, T.; Qi, J.; Chen, P.; Gurbuxani, S.; Arnovitz, S.; Strong, J.; Ferchen, K.; Ulrich, B.; Weng, H.; Wang, Y.; Huang, H.; Li, S.; Neilly, M.B.; Larson, R.A.; Le Beau, M.M.; Bohlander, S.K.; Jin, J.; Li, Z.; Bradner, J.E.; Hong, S.; Chen, J. Eradication of acute myeloid leukemia with FLT3 ligand-targeted miR-150 nanoparticles. Cancer Research, 2016, 76(15), 4470–4480. doi: 10.1158/0008-5472.CAN-15-2949
  56. Tsai, C.-Y.; Li, C.-W.; Li, J.-R.; Jang, B.-H.; Chen, S.-H. Steroid Probes Conjugated with Protein-Protected Gold Nanocluster: Specific and Rapid Fluorescence Imaging of Steroid Receptors in Target Cells. Journal of Fluorescence, 2016, 26(4), 1239–1248. doi: 10.1007/s10895-016-1811-6
  57. Priwitaningrum, D.L.; Blonde, J.-B.; van Baarlen, J.; Hennink, W.E.; Storm, G.; Le Gac, S.; Prakash, J. Tumor stroma-containing 3D spheroid arrays: A tool to study nanoparticle penetration. Journal of Controlled Release, 2016, 244(Part B), 257–268. doi: 10.1016/j.jconrel.2016.09.004
  58. Zhu, Y.; Wang, X.; Chen, J.; Zhang, J.; Meng, F.; Deng, C.; Cheng, R.; Feijen, J.; Zhong, Z. Bioresponsive and fluorescent hyaluronic acid-iodixanol nanogels for targeted X-ray computed tomography imaging and chemotherapy of breast tumors. Journal of controlled release, 2016, 244(Part B), 229–239. doi: 10.1016/j.jconrel.2016.08.027
  59. Zhang, L.; Navaratna, T.; Thurber, G.M. . A Helix-Stabilizing Linker Improves Subcutaneous Bioavailability of a Helical Peptide Independent of Linker Lipophilicity, 2016, 27(7), 1663–1672. doi: 10.1021/acs.bioconjchem.6b00209
  60. Wang, C.; Wang, X.; Dong, K.; Luo, J.; Zhang, Q.; Cheng, Y. Injectable and Responsively Degradable Hydrogel for Personalized Photothermal Therapy. Biomaterials, 2016, 104, 129–137. doi: 10.1016/j.biomaterials.2016.07.013
  61. Lu, X.; Jia, F.; Tan, X.; Wang, D.; Cao, X.; Zheng, J.; Zhang, K. Effective Antisense Gene Regulation via Noncationic, Polyethylene Glycol Brushes. Journal of the American Chemical Society, 2016, 138(29), 9097–9100. doi: 10.1021/jacs.6b05787
  62. Wang, C.; Tang, F.; Wang, X.; Li, L. Synthesis and application of biocompatible gold core-poly-(L-Lysine) shell nanoparticles. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2016, 506, 425–430. doi: 10.1016/j.colsurfa.2016.07.014
  63. Zhang, Y.; Li, Z.; Zhang, K.; Yang, G.; Wang, Z.; Zhao, J.; Hu, R.; Feng, N. Ethyl oleate-containing nanostructured lipid carriers improve oral bioavailability of trans-ferulic acid ascompared with conventional solid lipid nanoparticles. International Journal of Pharmaceutics, 2016, 511(1), 57–64. doi: 10.1016/j.ijpharm.2016.06.131
  64. Farzan, V.M.; Aparin, I.O.; Veselova, O.A.; Podkolzin, A.T.; Shipulin, G.A.; Korshun, V.A.; Zatsepin, T.S. Cy5/BHQ dye-quencher pairs in fluorogenic qPCR probes: effects of charge and hydrophobicity. Analytical Methods, 2016, 8(29), 5826–5831. doi: 10.1039/c6ay01304j
  65. Melle, A.; Balaceanu, A.; Kather, M.; Wu, Y.; Gau, E.; Sun, W.; Huang, X.; Shi, X.; Karperien, M.; Pich, A. Stimuli-Responsive Poly(N}-vinylcaprolactam-co-2-methoxyethyl acrylate) Core-Shell Microgels: Facile Synthesis, Modulation of Surface Properties and Controlled Internalisation into Cells. Journal of Materials Chemistry B, 2016, 4(30), 5127–5137. doi: 10.1039/c6tb01196a
  66. Boone, C.; Grove, R.; Adamcova, D.; Braga, C.; Adamec, J. Revealing oxidative damage to enzymes of carbohydrate metabolism in yeast: An integration of 2D DIGE, quantitative proteomics and bioinformatics. Proteomics, 2016, 16(13), 1889–1903. doi: 10.1002/pmic.201500546
  67. Wu, F.; Liu, C.; Chen, Y.; Yang, S.; Xu, J.; Huang, R.; Wang, X.; Li, M.; Liu, W.; Mao, W.; Zhou, X. Visualization of G-quadruplexes in gel and in live cells by a near-infrared fluorescent probe. Sensors and Actuators B: Chemical, 2016, 236, 268–275. doi: 10.1016/j.snb.2016.05.162
  68. Pérez-Medina, C.; Abdel-Atti, D.; Tang, J.; Zhao, Y.; Fayad, Z.A.; Lewis, J.S.; Mulder, W.J.M.; Reiner, T. Nanoreporter PET predicts the efficacy of anti-cancer nanotherapy. Nature Communications, 2016, 7, 11838. doi: 10.1038/ncomms11838
  69. Wilkinson, N.; Metaxas, A.; Ruud, E.; Raethke, E.; Wickramaratne, S.; Reineke, T.M.; Dutcher, C.S. Internal structure visualization of polymer – clay flocculants using fluorescence. Colloids and Interface Science Communications, 2016, 10–11, 1–5. doi: 10.1016/j.colcom.2016.03.002
  70. Wang, H.; Tang, L.; Liu, Y.; Dobrucka, I.T.; Dobrucki, L.W.; Yin, L.; Cheng, J. In Vivo Targeting of Metabolically Labeled Cancers with Ultra-Small Silica Nanoconjugates. Theranostics, 2016, 6(9), 1467–1476. doi: 10.7150/thno.16003
  71. Ngambenjawong, C.; Gustafson, H.H.; Pineda, J.M.; Kacherovsky, N.A.; Cieslewicz, M.; Pun, S.H. Serum Stability and Affinity Optimization of an M2 Macrophage-Targeting Peptide (M2pep). Theranostics, 2016, 6(9), 1403–1414. doi: 10.7150/thno.15394
  72. Chen, K.; Chen, Q.; Wang, K.; Zhu, J.; Li, W.; Li, W.; Qiu, L.; Guan, G.; Qiao, M.; Zhao, X.; Hu, H.; Chen, D. Synthesis and characterization of a PAMAM-OH derivative containing an acid-labile β-thiopropionate bond for gene delivery. International Journal of Pharmaceutics, 2016, 509(1–2), 314–327. doi: 10.1016/j.ijpharm.2016.05.060
  73. Kim, K.-M.; Kim, M.K.; Paek, H.-J.; Choi, S.-J.; Oh, J.-M. Stable fluorescence conjugation of ZnO nanoparticles and their size dependent cellular uptake. Colloids and Surfaces B: Biointerfaces, 2016, 145, 870–877. doi: 10.1016/j.colsurfb.2016.06.006
  74. Samuelsen, S.V.; Maity, A.; Nybo, M.; Macaubas, C.; Lønstrup, L.; Balboni, I.M.; Mellins, E.D.; Astakhova, K. Novel Phospholipid-Protein Conjugates Allow Improved Detection of Antibodies in Patients with Autoimmune Diseases. PLoS One, 2016, 11(6), e0156125. doi: 10.1371/journal.pone.0156125
  75. Huang, R.; Conti, P.S.; Chen, K. In Vivo Tumor Angiogenesis Imaging Using Peptide-Based Near-Infrared Fluorescent Probes. Methods in Molecular Biology, 2016, 1444, 73–84. doi: 10.1007/978-1-4939-3721-9_8
  76. Camerino, M.A.; Liu, M.; Moriya, S.; Kitahashi, T.; Mahgoub, A.; Mountford, S.J.; Chalmers, D.K.; Soga, T.; Parhar, I.S.; Thompson, P.E. Beta amino acid-modified and fluorescently labelled kisspeptin analogues with potent KISS1R activity. Journal of Peptide Science, 2016, 22(6), 406–414. doi: 10.1002/psc.2883
  77. Geng, L.; Wang, Z.; Jia, X.; Han, Q.; Xiang, Z.; Li, D.; Yang, X.; Zhang, D.; Bu, X.; Wang, W.; Hu, Z.; Fang, Q. HER2 Targeting Peptides Screening and Applications in Tumor Imaging and Drug Delivery. Theranostics, 2016, 6(8), 1261–1273. doi: 10.7150/thno.14302
  78. Richter-Heitmann, T.; Eickhorst, T.; Knauth, S.; Friedrich, M.W.; Schmidt, H. Evaluation of Strategies to Separate Root-Associated Microbial Communities: A Crucial Choice in Rhizobiome Research. Frontiers in Microbiology, 2016, 7, 773. doi: 10.3389/fmicb.2016.00773
  79. Soodgupta, D.; Zhou, H.; Beaino, W.; Lu, L.; Rettig, M.; Snee, M.; Skeath, J.; DiPersio, J.F.; Akers, W.J.; Laforest, R.; Anderson, C.J.; Tomasson, M.H.; Shokeen, M. Ex Vivo and In Vivo Evaluation of Overexpressed VLA-4 in Multiple Myeloma Using LLP2A Imaging Agents. Journal of Nuclear Medicine, 2016, 57(4), 640–645. doi: 10.2967/jnumed.115.164624
  80. Zhong, Q.; Merkel, O.M.; Reineke, J.J.; da Rocha, S.R.P. Effect of the Route of Administration and PEGylation of Poly(amidoamine) Dendrimers on their Systemic and Lung Cellular Biodistribution. Molecular Pharmaceutics, 2016, 13(6), 1866–1878. doi: 10.1021/acs.molpharmaceut.6b00036
  81. Ye, R.; Zhu, C.; Song, Y.; Lu, Q.; Ge, X.; Yang, X.; Zhu, M.-J.; Du, D.; Li, H.; Lin, Y. Bioinspired Synthesis of All-in-One Organic-Inorganic Hybrid Nanoflowers Combined with a Handheld pH Meter for On-Site Detection of Food Pathogen. Small, 2016, 12(23), 3094–3100. doi: 10.1002/smll.201600273
  82. Dou, Y.; Guo, J.; Chen, Y.; Han, S.; Xu, X.; Shi, Q.; Jia, Y.; Liu, Y.; Deng, Y.; Wang, R.; Li, X.; Zhang, J. Sustained delivery by a cyclodextrin material-based nanocarrier potentiates antiatherosclerotic activity of rapamycin via selectively inhibiting mTORC1 in mice. Journal of Controlled Release, 2016, 235, 48–62. doi: 10.1016/j.jconrel.2016.05.049
  83. Yang, Q.; Li, L.; Sun, W.; Zhou, Z.; Huang, Y. Dual Stimuli-Responsive Hybrid Polymeric Nanoparticles Self-Assembled from POSS-Based Star-Like Copolymer-Drug Conjugates for Efficient Intracellular Delivery of Hydrophobic Drugs. ACS Applied Materials & Interfaces, 2016, 8(21), 13251–13261. doi: 10.1021/acsami.6b02403
  84. Brinkman, A.M.; Chen, G.; Wang, Y.; Hedman, C.J.; Sherer, N.M.; Havighurst, T.C.; Gong, S.; Xu, W. Aminoflavone-Loaded EGFR-Targeted Unimolecular Micelle Nanoparticles Exhibit Anti-Cancer Effects in Triple Negative Breast Cancer. Biomaterials, 2016, 101, 20–31. doi: 10.1016/j.biomaterials.2016.05.041
  85. Ray, J.; Shin, I.; Ilgu, M.; Bendickson, L.; Gupta, V.; Kraus, G.A.; Nilsen-Hamilton, M. IMAGEtags: Quantifying mRNA Transcription in Real Time with Multiaptamer Reporters. Methods in Enzymology, 2016, 572, 193–213. doi: 10.1016/bs.mie.2016.02.028
  86. Bygd, H.C.; Bratlie, K.M. The effect of chemically modified alginates on macrophage phenotype and biomolecule transport. Journal of Biomedical Materials Research, 2016, 104(7), 1707–1719. doi: 10.1002/jbm.a.35700
  87. Rana, S.; Blowers, E.C.; Tebbe, C.; Contreras, J.I.; Radhakrishnan, P.; Kizhake, S.; Zhou, T.; Rajule, R.N.; Arnst, J.L.; Munkarah, A.R.; Rattan, R.; Natarajan, A. Isatin Derived Spirocyclic Analogues with α-Methylene-γ-butyrolactone as Anticancer Agents: A Structure-Activity Relationship Study. Journal of Medicinal Chemistry, 2016, 59(10), 5121–5127. doi: 10.1021/acs.jmedchem.6b00400
  88. Chiu, H.-Y.; Deng, W.; Engelke, H.; Helma, J.; Leonhardt, H.; Bein, T. Intracellular chromobody delivery by mesoporous silica nanoparticles for antigen targeting and visualization in real time. Scientific Reports, 2016, 6, 25019. doi: 10.1038/srep25019
  89. Sindhwani, S.; Syed, A.M.; Wilhelm, S.; Glancy, D.R.; Chen, Y.Y.; Dobosz, M.; Chan, W.C.W. Three-Dimensional Optical Mapping of Nanoparticle Distribution in Intact Tissues. ACS Nano, 2016, 10(5), 5468–5478. doi: 10.1021/acsnano.6b01879
  90. Xu, X.; Li, L.; Zhou, Z.; Sun, W.; Huang, Y. Dual-pH responsive micelle platform for co-delivery of axitinib and doxorubicin. International Journal of Pharmaceutics, 2016, 507(1–2), 50–60. doi: 10.1016/j.ijpharm.2016.04.060
  91. Hartley, J.M.; Zhang, R.; Gudheti, M.; Yang, J.; Kopeček, J. Tracking and quantifying polymer therapeutic distribution on a cellular level using 3D dSTORM. Journal of Controlled Release, 2016, 231, 50–59. doi: 10.1016/j.jconrel.2016.02.005
  92. Ngo, J.T.; Adams, S.R.; Deerinck, T.J.; Boassa, D.; Rodriguez-Rivera, F.; Palida, S.F.; Bertozzi, C.R.; Ellisman, M.H.; Tsien, R.Y. Click-EM for imaging metabolically tagged nonprotein biomolecules. Nature Chemical Biology, 2016, 12(6), 459–465. doi: 10.1038/nchembio.2076
  93. Bruckman, M.A.; Czapar, A.E.; VanMeter, A.; Randolph, L.N.; Steinmetz, N.F. Tobacco mosaic virus-based protein nanoparticles and nanorods for chemotherapy delivery targeting breast cancer. Journal of Controlled Release, 2016, 231, 103–113. doi: 10.1016/j.jconrel.2016.02.045
  94. Tran, T.-H.; Krishnan, S.; Amiji, M.M. MicroRNA-223 Induced Repolarization of Peritoneal Macrophages Using CD44 Targeting Hyaluronic Acid Nanoparticles for Anti-Inflammatory Effects. PLoS One, 2016, 11(5), e0152024. doi: 10.1371/journal.pone.0152024
  95. Shen, T.; Guan, S.; Gan, Z.; Zhang, G.; Yu, Q. Polymeric Micelles with Uniform Surface Properties and Tunable Size and Charge: Positive Charges Improve Tumor Accumulation. Biomacromolecules, 2016, 17(5), 1801–1810. doi: 10.1021/acs.biomac.6b00234
  96. Zhao, L.; Yuan, W.; Ang, C.Y.; Qu, Q.; Dai, Y.; Gao, Y.; Luo, Z.; Wang, J.; Chen, H.; Li, M.; Li, F.; Zhao, Y. Silica-Polymer Hybrid with Self-Assembled PEG Corona Excreted Rapidly via a Hepatobiliary Route. Advanced Functional Materials, 2016, 26(18), 3036–3047. doi: 10.1002/adfm.201505155
  97. Liu, C.; Stonestrom, A.J.; Christian, T.; Yong, J.; Takase, R.; Hou, Y.-M.; Yang, X. Molecular Basis and Consequences of the Cytochrome c-tRNA Interaction. Journal of Biological Chemistry, 2016, 291(19), 10426–10436. doi: 10.1074/jbc.M115.697789
  98. Al-Hilal, T.A.; Chung, S.W.; Choi, J.U.; Alam, F.; Park, J.; Kim, S.W.; Kim, S.Y.; Ahsan, F.; Kim, I.-S.; Byun, Y. Targeting prion-like protein doppel selectively suppresses tumor angiogenesis. Journal of Clinical Investigation, 2016, 126(4), 1251–1266. doi: 10.1172/JCI83427
  99. Chen, G.; Jaskula-Sztul, R.; Harrison, A.; Dammalapati, A.; Xu, W.; Cheng, Y.; Chen, H.; Gong, S. KE108-Conjugated Unimolecular Micelles Loaded with a Novel HDAC Inhibitor Thailandepsin-A for Targeted Neuroendocrine Cancer Therapy. Biomaterials, 2016, 97, 22–33. doi: 10.1016/j.biomaterials.2016.04.029
  100. Liu, T.; Yuan, X.; Jia, T.; and Liu, C.; Ni, Z.; Qin, Z.; Yuan, Y. Polymeric Prodrug of Bufalin for Increasing Solubility and Stability: Synthesis and Anticancer Study in Vitro and in Vivo. International Journal of Pharmaceutics, 2016, 506(1–2), 382–393. doi: 10.1016/j.ijpharm.2016.04.041
  101. Jiang, X.; Hu, C.; Arnovitz, S.; Bugno, J.; Yu, M.; Zuo, Z.; Chen, P.; Huang, H.; Ulrich, B.; Gurbuxani, S.; Weng, H.; Strong, J.; Wang, Y.; Li, Y.; Salat, J.; Li, S.; Elkahloun, A.G.; Yang, Y.; Neilly, M.B.; Larson, R.A.; Le Beau, M.M.; Herold, T.; Bohlander, S.K.; Liu, P.P.; Zhang, J.; Li, Z.; He, C.; Jin, J.; Hong, S.; Chen, J.;. miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia. Nature Communications, 2016, 7, 11452. doi: 10.1038/ncomms11452
  102. Pan, G.; Bao, Y.-J.; Xu, J.; Liu, T.; Liu, C.; Qiu, Y.-Y.; Shi, X.-J.; Yu, H.; Jia, T.-T.; Yuan, X.; Yuan, Z.-T.; Yin, P.-H.; Cao, Y.-J. Esterase-responsive polymeric prodrug-based tumor targeting nanoparticles for improved anti-tumor performance against colon cancer. RSC Advances, 2016, 6(48), 42109–42119. doi: 10.1039/c6ra05236c
  103. Kelkar, S.S.; Hill, T.K.; Marini, F.C.; Mohs, A.M. Near infrared fluorescent nanoparticles based on hyaluronic acid: self-assembly, optical properties, and cell interaction. Acta Biomaterialia, 2016, 36, 112–121. doi: 10.1016/j.actbio.2016.03.024
  104. Li, L.; Sun, W.; Zhang, Z.; Huang, Y. Time-staggered delivery of docetaxel and H1S6A,F8A peptide for sequential dual-strike chemotherapy through tumor priming and nuclear targeting. Journal of Controlled Release, 2016, 232, 62–74. doi: 10.1016/j.jconrel.2016.04.021
  105. Zhou, Y.; Li, W.; Xiao, Y. Profiling of Multiple Targets of Artemisinin Activated by Hemin in Cancer Cell Proteome. ACS Chemical Biology, 2016, 11(4), 882–888. doi: 10.1021/acschembio.5b01043
  106. Puthenveetil, S.; Musto, S.; Loganzo, F.; Tumey, L.N.; O'Donnell, C.J.; Graziani, E.I. Development of solid-phase site-specific conjugation and its application towards generation of dual labeled antibody and Fab drug conjugates. Bioconjugate Chemistry, 2016, 27(4), 1030–1039. doi: 10.1021/acs.bioconjchem.6b00054
  107. Zhao, Y.; Fay, F.; Hak, S.; Manuel Perez-Aguilar, J.; Sanchez-Gaytan, B.L.; Goode, B.; Duivenvoorden, R.; de Lange Davies, C.; Bjørkøy, A.; Weinstein, H.; Fayad, Z.A.; Pérez-Medina, C.; Mulder, W.J.M. Augmenting drug-carrier compatibility improves tumour nanotherapy efficacy. Nature Communications, 2016, 7, 11221. doi: 10.1038/ncomms11221
  108. Kwok, S.J.J.; Choi, M.; Bhayana, B.; Zhang, X.; Ran, C.; Yun, S.-H. Two-photon excited photoconversion of cyanine-based dyes. Scientific Reports, 2016, 6, 23866. doi: 10.1038/srep23866
  109. Markovic, S.; Belz, J.; Kumar, R.; Cormack, R.A.; Sridhar, S.; Niedre, M. Near-infrared fluorescence imaging platform for quantifying in vivo nanoparticle diffusion from drug loaded implants. International Journal of Nanomedicine, 2016, 11, 1213–1223. doi: 10.2147/IJN.S93324
  110. Dhande, Y.K.; Wagh, B.S.; Hall, B.C.; Sprouse, D.; Hackett, P.B.; Reineke, T.M. N-Acetylgalactosamine Block-co-Polycations Form Stable Polyplexes with Plasmids and Promote Liver-Targeted Delivery. Biomacromolecules, 2016, 17(3), 830–840. doi: 10.1021/acs.biomac.5b01555
  111. Ravar, F.; Saadat, E.; Gholami, M.; Dehghankelishady, P.; Mahdavi, M.; Azami, S.; Dorkoosh, F.A. Hyaluronic acid-coated liposomes for targeted delivery of paclitaxel, in-vitro characterization and in-vivo evaluation. Journal of Controlled Release, 2016, 229, 10–22. doi: 10.1016/j.jconrel.2016.03.012
  112. Braner, M.; Kollmannsperger, A.; Wieneke, R.; Tampé, R. ’Traceless’ Tracing of Proteins – High-Affinity Trans-Splicing Directed by a Minimal Interaction Pair. Chemical Science, 2016, 7(4), 2646–2652. doi: 10.1039/C5SC02936H
  113. Gupta, A.; Verma, N.C.; Khan, S.; Tiwari, S.; Chaudhary, A.; Nandi, C.K. Paper strip based and live cell ultrasensitive lead sensor using carbon dots synthesized from biological media. Sensors and Actuators B: Chemical, 2016, 232, 107–114. doi: 10.1016/j.snb.2016.03.110
  114. Guldris, N.; Argibay, B.; Kolen'ko, Y.V.; Carbó-Argibay, E.; Sobrino, T.; Campos, F.; Salonen, L.M.; Bañobre-López, M.; Castillo, J.; Rivas, J. Influence of the Separation Procedure on the Properties of Magnetic Nanoparticles: Gaining in vitro Stability and T1‐T2 Magnetic Resonance Imaging Performance. Journal of Colloid and Interface Science, 2016, 472, 229–236. doi: 10.1016/j.jcis.2016.03.040
  115. Li, L.; Grausam, K.B.; Wang, J.; Lun, M.P.; Ohli, J.; Lidov, H.G.W.; Calicchio, M.L.; Zeng, E.; Salisbury, J.L.; Wechsler-Reya, R.J.; Lehtinen, M.K.; Schüller, U.; Zhao, H. Sonic Hedgehog promotes proliferation of Notch-dependent monociliated choroid plexus tumour cells. Nature Cell Biology, 2016, 18(4), 418–430. doi: 10.1038/ncb3327
  116. Ponomarenko, A.I.; Brylev, V.A.; Sapozhnikova, K.A.; Ustinov, A.V.; Prokhorenko, I.A.; Zatsepin, T.S.; Korshun, V.A. Tetrahedral DNA conjugates from pentaerythritol-based polyazides. Tetrahedron, 2016, 72(19), 2386–2391. doi: 10.1016/j.tet.2016.03.051
  117. Seo, K.-H.; Chu, H.-S.; Yoo, T.H.; Lee, S.-G.; Won, J.-I. Separation efficiency of free-solution conjugated electrophoresis with drag-tags incorporating a synthetic amino acid. Electrophoresis, 2016, 37(5–6), 818–825. doi: 10.1002/elps.201500506
  118. Bertrand, A.; Bipfubusa, M.; Castonguay, Y.; Rocher, S.; Szopinska-Morawska, A.; Papadopoulos, Y.; Renaut, J. A proteome analysis of freezing tolerance in red clover (Trifolium pratense L.). BMC Plant Biology, 2016, 16, 65. doi: 10.1186/s12870-016-0751-2
  119. Kim, J.B.; Park, K.; Ryu, Ji.; Lee, J.J.; Lee, M.W.; Cho, H.S.; Nam, H.S.; Park, O.K.; Song, J.W.; Kim, T.S.; Oh, D.J.; Gweon, D.; Oh, W.-Y.; Yoo, H.; Kim, J.W. Intravascular optical imaging of high-risk plaques in vivo by targeting macrophage mannose receptors. Scientific Reports, 2016, 6, 22608. doi: 10.1038/srep22608
  120. Cai, X.; Jin, R.; Wang, J.; Yue, D.; Jiang, Q.; Wu, Y.; Gu, Z. Bioreducible Fluorinated Peptide Dendrimers Capable of Circumventing Various Physiological Barriers for Highly Efficient and Safe Gene Delivery. ACS Applied Materials & Interfaces, 2016, 8(9), 5821–5832. doi: 10.1021/acsami.5b11545
  121. Leenders, J.; Baker, M.B.; Pijpers, I.; Lafleur, R.; Albertazzi, L.; Palmans, A.R.A.; Meijer, E.W. Supramolecular polymerisation in water; elucidating the role of hydrophobic and hydrogen-bond interactions. Soft Matter, 2016, 12, 2887–2893. doi: 10.1039/c5sm02843d
  122. Pitek, A.S.; Jameson, S.A.; Veliz, F.A.; Shukla, S.; Steinmetz, N.F. Serum Albumin "Camouflage" of Plant Virus Based Nanoparticles Prevents Their Antibody Recognition and Enhances Pharmacokinetics. Biomaterials, 2016, 89, 89–97. doi: 10.1016/j.biomaterials.2016.02.032
  123. Ma, G.; Zhao, Z.; Liu, H. Yeast Cells Encapsulating Polymer Nanoparticles as Trojan Particles via in Situ Polymerization inside Cells. Macromolecules, 2016, 49(5), 1545–1551. doi: 10.1021/acs.macromol.6b00016
  124. Iyisan, B.; Kluge, J.; Formanek, P.; Voit, B.; Appelhans, D. Multifunctional and Dual-Responsive Polymersomes as Robust Nanocontainers: Design, Formation by Sequential Post-Conjugations, and pH-Controlled Drug Release. Chemistry of Materials, 2016, 28(5), 1513–1525. doi: 10.1021/acs.chemmater.5b05016
  125. Xue, M.; Wei, W.; Su, Y.; Johnson, D.; Heath, J.R. Supramolecular Probes for Assessing Glutamine Uptake Enable Semi-Quantitative Metabolic Models in Single Cells. Journal of the American Chemical Society, 2016, 138(9), 3085–3093. doi: 10.1021/jacs.5b12187
  126. Rabinsky, E.F.; Joshi, B.P.; Pant, A.; Zhou, J.; Duan, X.; Smith, A.; Kuick, R.; Fan, S.; Nusrat, A.; Owens, S.R.; Appelman, H.D.; Wang, T.D. Overexpressed claudin-1 can be endoscopically visualized in colonic adenomas in vivo. CMGH Cellular and Molecular Gastroenterology and Hepatology, 2016, 2(2), 222–237. doi: 10.1016/j.jcmgh.2015.12.001
  127. Sun, S.; Błażewska, K.M.; Kadina, A.P.; Kashemirov, B.A.; Duan, X.; Triffitt, J.T.; Dunford, J.E.; Russell, R.G.G.; Ebetino, F.H.; Roelofs, A.J.; Coxon, F.P.; Lundy, M.W.; McKenna, C.E. Fluorescent Bisphosphonate and Carboxyphosphonate Probes: A Versatile Imaging Toolkit for Applications in Bone Biology and Biomedicine. Bioconjugate Chemistry, 2016, 27(2), 329–340. doi: 10.1021/acs.bioconjchem.5b00369
  128. Rombouts, K.; Braeckmans, K.; Remaut, K. Fluorescent labeling of plasmid DNA and messenger RNA: gains and losses of current labeling strategies. Bioconjugate Chemistry, 2016, 27(2), 280–297. doi: 10.1021/acs.bioconjchem.5b00579
  129. Liu, X.; Zhang, P.; He, D:; Rödl, W.; Preiß, T.; Rädler, J.O.; Wagner, E.; Lächelt, U. pH-reversible cationic RNase A conjugates for enhanced cellular delivery and tumor cell killing. Biomacromolecules, 2016, 17(1), 173–182. doi: 10.1021/acs.biomac.5b01289
  130. Kijima, S.T.; Hirose, K.; Kong, S.-G.; Wada, M.; Uyeda, T.Q.P. Distinct Biochemical Properties of Arabidopsis thaliana Actin Isoforms. Plant and Cell Physiology, 2016, 57(1), 46–56. doi: 10.1093/pcp/pcv176
  131. Wang, X.; Song, P.; Peng, L.; Tong, A.; Xiang, Y. Aggregation-Induced Emission Luminogen-Embedded Silica Nanoparticles Containing DNA Aptamers for Targeted Cell Imaging. ACS Applied Materials & Interfaces, 2016, 8(1), 609–616. doi: 10.1021/acsami.5b09644
  132. Tolstyka, Z.P.; Phillips, H.; Cortez, M.; Wu, Y.; Ingle, N.; Bell, J.B.; Hackett, P.B.; Reineke, T.M. Trehalose-Based Block Copolycations Promote Polyplex Stabilization for Lyophilization and in Vivo pDNA Delivery. ACS Biomaterials Science & Engineering, 2016, 2(1), 43–55. doi: 10.1021/acsbiomaterials.5b00312
  133. Schelpe, J.; Monté, D.; Dewitte, F.; Sixma, T.K.; Rucktooa, P. Structure of UBE2Z Enzyme Provides Functional Insight into Specificity in the FAT10 Protein Conjugation Machinery. Journal of Biological Chemistry, 2016, 291(2), 630–639. doi: 10.1074/jbc.M115.671545
  134. Yoshimatsu, T.; D'Orazi, F.D.; Gamlin, C.R.; Suzuki, S.C.; Suli, A.; Kimelman, D.; Raible, D.W.; Wong, R.O. Presynaptic partner selection during retinal circuit reassembly varies with timing of neuronal regeneration in vivo. Nature Communications, 2016, 7, 10590. doi: 10.1038/ncomms10590
  135. Li, Z.; Liu, Z.; Chen, Z.; Ju, E.; Li, W.; Ren, J.; Qu, X. Bioorthogonal chemistry for selective recognition, separation and killing bacteria over mammalian cells. Chemical Communications, 2016, 52(17), 3482–3485. doi: 10.1039/c5cc10625g
  136. Panth, K.M.; van den Beucken, T.; Biemans, R.; Lieuwes, N.G.; Weber, M.; Losen, M.; Yaromina, A.; Dubois, L.J.; Lambin, P. In vivo optical imaging of MMP2 immuno protein antibody: tumor uptake is associated with MMP2 activity. Scientific Reports, 2016, 6, 22198. doi: 10.1038/srep22198
  137. Kryvalap, Y.; Lo, C.-W.; Manuylova, E.; Baldzizhar, R.; Jospe, N.; Czyzyk, J. Antibody Response to Serpin B13 Induces Adaptive Changes in Mouse Pancreatic Islets and Slows Down the Decline in the Residual Beta Cell Function in Children with Recent Onset of Type 1 Diabetes Mellitus. Journal of Biological Chemistry, 2016, 291(1), 266–278. doi: 10.1074/jbc.M115.687848
  138. Turcheniuk, K.; Dumych, T.; Bilyy, R.; Turcheniuk, V.; Bouckaert, J.; Vovk, V.; Chopyak, V.; Zaitsev, V.; Mariot, P.; Prevarskaya, N.; Boukherrouba, R.; Szunerits, S. Plasmonic photothermal cancer therapy with gold nanorods/reduced graphene oxide core/shell nanocomposites. RSC Advances, 2016, 6(2), 1600–1610. doi: 10.1039/c5ra24662h
  139. Wang, X.; Wang, C.; Zhang, Q.; Cheng, Y. Near Infrared Light-responsive and Injectable Supramolecular Hydrogels for On-demand Drug Delivery. Chemical Communications, 2016, 52, 978–981. doi: 10.1039/c5cc08391e
  140. He, H.; Altomare, D.; Ozer, U.; Xu, H.; Creek, K.; Chen, H.; Xu, P. Cancer cell-selective killing polymer/copper combination. Biomaterials Science, 2016, 4(1), 115–120. doi: 10.1039/c5bm00325c
  141. Poongavanam, M.-V.; Kisley, L.; Kourentzi, K.; Landes, C.F.; Willson, C. Ensemble and Single-Molecule Biophysical Characterization of D17.4 DNA Aptamer-IgE Interactions. Biochimica et Biophysica Acta, 2016, 1864(1), 154–164. doi: 10.1016/j.bbapap.2015.08.008
  142. Saita, M.; Kaneko, J.; Sato, T.; Takahashi, S.; Takahashi, S.W.; Kawamata, R.; Sakurai, T.; Lee, M.-C.; Hamada, N.; Kimoto, K.; Nagasaki, Y. Novel antioxidative nanotherapeutics in a rat periodontitis model: Reactive oxygen species scavenging by redox injectable gel suppresses alveolar bone resorption. Biomaterials, 2016, 76, 292–301. doi: 10.1016/j.biomaterials.2015.10.077
  143. Nusshold, C.; Üllen, A.; Kogelnik, N.; Bernhart, E.; Reicher, H.; Plastira, I.; Glasnov, T.; Zangger, K.; Rechberger, G.; Kollroser, M.; Fauler, G.; Wolinski, H.; Weksler, B.B.; Romero, I.A.; Kohlwein, S.D.; Couraud, P.-O.; Malle, E.; Sattler, W. Assessment of electrophile damage in a human brain endothelial cell line utilizing a clickable alkyne analogue of 2-chlorohexadecanal. Free Radical Biology and Medicine, 2016, 90, 59–74. doi: 10.1016/j.freeradbiomed.2015.11.010
  144. van der Velde, J.H.M.; Oelerich, J.; Huang, J.; Smit, J.H.; Aminian Jazi, A.; Galiani, S.; Kolmakov, K.; Guoridis, G.; Eggeling, C.; Herrmann, A.; Roelfes, G.; Cordes, T. A simple and versatile design concept for fluorophore derivatives with intramolecular photostabilization. Nature Communications, 2016, 7, 10144. doi: 10.1038/ncomms10144
  145. Zhang, L.; Thurber, G.M. Quantitative Impact of Plasma Clearance and Down-regulation on GLP-1 Receptor Molecular Imaging. Molecular Imaging and Biology, 2016, 18(1), 79–89. doi: 10.1007/s11307-015-0880-2
  146. Poolman, J.; Maity, C.; Boekhoven, J.; van der Mee, L.; le Sage, V.; Groenewold, M.; van Kasteren, S.; Versluis, F.; van Esch, J.; Eelkema, R. A toolbox for controlling the properties and functionalisation of hydrazone-based supramolecular hydrogels. Journal of Materials Chemistry B, 2016, 4, 852–858. doi: 10.1039/C5TB01870F
  147. Aparin, I.O.; Farzan, V.M.; Veselova, O.A.; Chistov, A.A.; Podkolzin, A.T.; Ustinov, A.V.; Shipulin, G.A.; Formanovsky, A.A.; Korshun, V.A.; Zatsepin, T.S. 1-Phenylethynylpyrene (PEPy) as a novel blue-emitting dye for qPCR assay. Analyst, 2016, 141, 1331–1338. doi: 10.1039/c5an01767j
  148. Joshi, B.P.; Zhou, J.; Pant, A.; Duan, X.; Zhou, Q.; Kuick, R.; Owens, S.R.; Appelman, H.; Wang, T.D. Design and Synthesis of Near-Infrared Peptide for in Vivo Molecular Imaging of HER2. Bioconjugate Chemistry, 2016, 27(2), 481–494. doi: 10.1021/acs.bioconjchem.5b00565
  149. Stephen, Z.; Dayringer, C.; Lim, J.; Revia, R.; Halbert, M.; Jeon, M.; Bakthavatsalam, A.; Ellenbogen, R.G.; Zhang, M. An Approach to Rapid Synthesis and Functionalization of Iron Oxide Nanoparticles for High Gene Transfection. ACS Applied Materials & Interfaces, 2016, 8(10), 6320–6328. doi: 10.1021/acsami.5b10883
  150. Park, H.; Koo, J.Y.; Srikanth, Y.V.V.; Oh, S.; Lee, J.; Park, J.; Park, S.B. Nonspecific protein labeling of photoaffinity linkers correlates with their molecular shapes in living cells. Chemical Communications, 2016, 52(34), 5828–5831. doi: 10.1039/c6cc01426g
  151. Gaitzsch, J.; Delahaye, M.; Poma, A.; Du Prez, F.; Battaglia, G. Comparison of metal free polymer-dye conjugation strategies in protic solvents. Polymer Chemistry, 2016, 7(17), 3046–3055;. doi: 10.1039/c6py00518g
  152. Subedi, M.; Minn, I.; Chen, J.; Kim, Y.; Ok, K.; Jung, Y.W.; Pomper, M.G.; Byun, Y. Design, synthesis and biological evaluation of PSMA/hepsin-targeted heterobivalent ligands. European Journal of Medicinal Chemistry, 2016, 118, 208–218. doi: 10.1016/j.ejmech.2016.04.033
  153. Shebl, B., Menke, D.E.; Pennella, M.; Poudyal, R.R.; Burke, D.H.; Cornish, P.V. Preparation of ribosomes for smFRET studies: A simplified approach. Archives of Biochemistry and Biophysics, 2016, 603, 118–130. doi: 10.1016/j.abb.2016.05.010
  154. Yoshimura, T.; Harashima, M.; Kurogi, K.; Suiko, M.; Liu, M.-C.; Sakakibara, Y. A novel procedure for the assessment of the antioxidant capacity of food components. Analytical Biochemistry, 2016, 507, 7–12. doi: 10.1016/j.ab.2016.05.002
  155. Bipfubusa, M.; Rocher, S.; Bertrand, A.; Castonguay, Y.; Renaut, J. Dataset of protein changes induced by cold acclimation in red clover (Trifolium pratense L.) populations recurrently selected for improved freezing tolerance. Data in Brief, 2016, 8, 570–574. doi: 10.1016/j.dib.2016.06.003
  156. Zhang, Z.; Cai, H.; Liu, Z.; Yao, P. Effective Enhancement of Hypoglycemic Effect of Insulin by Liver-targeted Nanoparticles Containing Cholic Acid-modified Chitosan Derivative. Molecular Pharmaceutics, 2016, 13(7), 2433–2442. doi: 10.1021/acs.molpharmaceut.6b00188
  157. Khaliq, N.U.; Park, D.Y.; Lee, J.Y.; Joo, Y.; Oh, K.S.; Kim, J.S.; Kim, J.-S.; Kim, I.-S.; Kwon, I.C.; Yuk, S.H. The multilayer nanoparticles for deep penetration of docetaxel into tumor parenchyma to overcome tumor microenvironment. Colloids and Surfaces B: Biointerfaces, 2016, 146, 833–840. doi: 10.1016/j.colsurfb.2016.07.034
  158. Gao, P.; Hunter, A.J.; Summe, M.J.; Phillip, W.A. A Method for the Efficient Fabrication of Multifunctional Mosaic Membranes by Inkjet Printing. ACS Applied Materials & Interfaces, 2016, 8(30), 19772–19779. doi: 10.1021/acsami.6b06048
  159. Horning, D.P.; Joyce, G.F. Amplification of RNA by an RNA polymerase ribozyme. Proceedings of the National Academy of Sciences of the United States of America, 2016, 113(35), 9786–9791. doi: 10.1073/pnas.1610103113
  160. Chadda, R.; Krishnamani, V.; Mersch, K.; Wong, J.; Brimberry, M.; Chadda, A.; Kolmakova-Partensky, L.; Friedman, L.J.; Gelles, J.; Robertson, J.L. The dimerization equilibrium of a ClC Cl−/H+ antiporter in lipid bilayers. eLIFE, 2016, 5, e17438. doi: 10.7554/eLife.17438
  161. Du, N.; Guo, W.; Yu, Q.; Guan, S.; Guo, L.; Shen, T.; Tang, H.; Gan, Z. Poly(D,L-lactic acid)-block-poly(N-(2-hydroxypropyl)methacrylamide) nanoparticles for overcoming accelerated blood clearance and achieving efficient anti-tumor therapy. Polymer Chemistry, 2016, 7(36), 5719–5729. doi: 10.1039/c6py01113f
  162. Shao, J.; Xie, H.; Huang, H.; Li, Z.; Sun, Z.; Xu, Y.; Xiao, Q.; Yu, X.-F.; Zhao, Y.; Zhang, H.; Wang, H.; Chu, P.K. Biodegradable black phosphorus-based nanospheres for in vivo photothermal cancer therapy. Nature communications, 2016, 7, 12967. doi: 10.1038/ncomms12967
  163. Hu, H.; Li, Y.; Zhou, Q.; Ao, Y.; Yu, C.; Wan, Y.; Xu, H.-B.; Li, Z.; Yang, X. Redox-sensitive hydroxyethyl starch-doxorubicin conjugate for tumor targeted drug delivery. ACS Applied Materials & Interfaces, 2016, 8(45), 30833–30844. doi: 10.1021/acsami.6b11932
  164. Chen, Y.; Luan, J.; Shen, W.; Lei, K.; Yu, L.; Ding, J. Injectable and thermosensitive hydrogel containing liraglutide as a long-acting anti-diabetic system. ACS Applied Materials & Interfaces, 2016, 8(45), 30703–30713. doi: 10.1021/acsami.6b09415
  165. Zhao, Y.; Wei, Z.; Zhao, H.; Jia, J.; Chen, Z.; Zhang, S.; Ouyang, Z.; Ma, X.; Zhang, X. In situ Ion-Transmission Mass Spectrometry for Paper-Based Analytical Devices. Analytical Chemistry, 2016, 88(22), 10805–10810. doi: 10.1021/acs.analchem.6b03272
  166. Matsuo, Y.; Maurer, S.P.; Yukawa, M.; Zakian, S.; Singleton, M.R.; Surrey, T.; Toda, T. An unconventional interaction between Dis1/TOG and Mal3/EB1 promotes the fidelity of chromosome segregation. Journal of Cell Science, 2016, 129(24), 4592–4606. doi: 10.1242/jcs.197533
  167. Li, W.; Zhou, Y.; Tang, G.; Xiao, Y. Characterization of the Artemisinin Binding Site for Translationally Controlled Tumor Protein (TCTP) by Bioorthogonal Click Chemistry. Bioconjugate Chemistry, 2016, 27(12), 2828–2833. doi: 10.1021/acs.bioconjchem.6b00556
  168. Song, X.; Hong, S.-H.; Kwon, W.T.; Bailey, L.M.; Basse, P.; Bartlett, D.L.; Kwon, Y.T.; Lee, Y.J. Secretory TRAIL-armed Natural Killer Cell-based Therapy: In Vitro and In Vivo Colorectal Peritoneal Carcinomatosis Xenograft. Molecular Cancer Therapeutics, 2016, 15(7), 1591-1601. doi: 10.1158/1535-7163.MCT-15-0937
  169. Gupta, M.; Nayyar, N.; Chawla, M.; Sitaraman, R.; Bhatnagar, R.; Banerjee, N. The Chromosomal parDE2 Toxin–Antitoxin System of Mycobacterium tuberculosis H37Rv: Genetic and Functional Characterization. Frontiers in Microbiology, 2016, 7, 886. doi: 10.3389/fmicb.2016.00886
  170. Cai, J.; Gu, B.; Cao, F.; Liu, S. A transferrin-target magnetic/fluorescent dual-mode probe significantly enhances the diagnosis of non-small cell lung cancer. Oncotarget, 2016, 7(26), 40047-40059. doi: 10.18632/oncotarget.9482
  171. Liu, T.; Jia, T.; Yuan, X.; Liu, C.; Sun, J.; Ni, Z.; Xu, J.; Wang, X.; Yuan, Y. Development of octreotide-conjugated polymeric prodrug of bufalin for targeted delivery to somatostatin receptor 2 overexpressing breast cancer in vitro and in vivo. International Journal of Nanomedicine, 2016, 11, 2235-2250. doi: 10.2147/IJN.S100404

2015

  1. Alam, F.; Chung, S.W.; Hwang, S.R.; Kim, J.-y.; Park, J.; Moon, H.T.; Byun, Y. Preliminary safety evaluation of a taurocholate-conjugated low-molecular-weight heparin derivative (LHT7): a potent angiogenesis inhibitor. Journal of Applied Toxicology, 2015, 35(1), 104–115. doi: 10.1002/jat.2995
  2. Gremse, F.; Doleschel, D.; Zafarnia, S.; Babler, A.; Jahnen-Dechent, W.; Lammers, T.; Lederle, W.; Kiessling, F. Hybrid µCT-FMT imaging and image analysis. Journal of Visualized Experiments, 2015, e52770. doi: 10.3791/52770
  3. Wang, H.; Li, D.; Liu, S.; Liu, R.; Yuan, H.; Krasnoperov, V.; Shan, H.; Conti, P.S.; Gill, P.S.; Li, Z. Small-Animal PET Imaging of Pancreatic Cancer Xenografts Using a 64Cu-Labeled Monoclonal Antibody, MAb159. Journal of Nuclear Medicine, 2015, 56(6), 908–913. doi: 10.2967/jnumed.115.155812
  4. Mahmoodi, M.M.; Rashidian, M.; Zhang, Y.; Distefano, M.D. Application of meta- and para- Phenylenediamine as Enhanced Oxime Ligation Catalysts for Protein Labeling, PEGylation, Immobilization, and Release. Current Protocols in Protein Science, 2015, 79, 15.4.1–15.4.28. doi: 10.1002/0471140864.ps1504s79
  5. Zhang, Rui and Yang, Jiyuan and Chu, Te-Wei and Hartley, Jonathan M. and Kopeček, Jindřich. Multimodality Imaging of Coiled-Coil Mediated Self-Assembly in a "Drug-Free" Therapeutic System. Advanced Healthcare Materials, 2015, 4(7), 1054–1065. doi: 10.1002/adhm.201400679
  6. Shrivastava, R.; Köster, D.; Kalme, S.; Mayor, S.; Neerathilingam, M. Tailor-made ezrin actin binding domain to probe its interaction with actin in-vitro. PLoS One, 2015, 10(4), e0123428. doi: 10.1371/journal.pone.0123428
  7. Evans, L.E.; Cheeseman, M.D.; Yahya, N.; Jones, K. Investigating Apoptozole as a Chemical Probe for HSP70 Inhibition. PLoS One, 2015, 10(10), e0140006. doi: 10.1371/journal.pone.0140006
  8. Schembri, L.S.; Stoddart, L.A.; Briddon, S.J.; Kellam, B.; Canals, M.; Graham, B.; Scammells, P.J. Synthesis, Biological Evaluation, and Utility of Fluorescent Ligands Targeting the μ-Opioid Receptor. Journal of Medicinal Chemistry, 2015, 58(24), 9764–9767. doi: 10.1021/acs.jmedchem.5b01664
  9. Chu, D.; Gao, J.; Wang, Z. Neutrophil-Mediated Delivery of Therapeutic Nanoparticles across Blood Vessel Barrier for Treatment of Inflammation and Infection. ACS Nano, 2015, 9(12), 11800–11811. doi: 10.1021/acsnano.5b05583
  10. Bu, J.; Pilo, A.L.; McLuckey, S.A. Gas Phase Click Chemistry via Ion/Ion Reactions. International Journal of Mass Spectrometry, 2015, 390, 118–123. doi: 10.1016/j.ijms.2015.05.010
  11. Rudnick-Glick, S.; Corem-Salkmon, E.; Grinberg, I.; Yehuda, R.; Margel, S. Near IR fluorescent conjugated poly(ethylene glycol)bisphosphonate nanoparticles for in vivo bone targeting in a young mouse model. Journal of Nanobiotechnology, 2015, 13(1), 80. doi: 10.1186/s12951-015-0126-0
  12. Koo, H.; Choi, M.; Kim, E.; Hahn, S.K.; Weissleder, R.; Yun, S.H. Bioorthogonal Click Chemistry-Based Synthetic Cell Glue. Small, 2015, 11(48), 6458–6466. doi: 10.1002/smll.201502972
  13. Lehtivuori, H.; Bhattacharya, S.;Angenent-Mari, N.M.; Satyshur, K.A.; Forest, K.T. Removal of Chromophore-Proximal Polar Atoms Decreases Water Content and Increases Fluorescence in a Near Infrared Phytofluor. Frontiers in Molecular Biosciences, 2015, 2, 65. doi: 10.3389/fmolb.2015.00065
  14. Wang, Z.; Zourelias, L.; Wu, C.; Edwards, P.C.; Trombetta, M.; Passineau, M.J. Ultrasound-assisted nonviral gene transfer of AQP1 to the irradiated minipig parotid gland restores fluid secretion. Gene Therapy, 2015, 22, 739–749. doi: 10.1038/gt.2015.36
  15. Sun, L.; Gai, Y.; Anderson, C.J.; Zeng, D. Highly-efficient and versatile fluorous-tagged Cu(I)-catalyzed azide–alkyne cycloaddition ligand for preparing bioconjugates. Chemical Communications, 2015, 51, 17072–17075. doi: 10.1039/C5CC06858D
  16. Cilliers, C.; Liao, J.; Atangcho, L.; Thurber, G.M. Residualization Rates of Near-Infrared Dyes for the Rational Design of Molecular Imaging Agents. Molecular Imaging and Biology, 2015, 17(6), 757–762. doi: 10.1007/s11307-015-0851-7
  17. Calver, C.F.; Liu, H.-W.; Cosa, G. Exploiting Conjugated Polyelectrolyte Photophysics towards Monitoring Real-Time Lipid Membrane-Surface Interaction Dynamics at the Single Particle Level. Langmuir, 2015, 31(43), 11842–11850. doi: 10.1021/acs.langmuir.5b00979
  18. Alexander, S.C.; Busby, K.N.; Cole, C.M.; Zhou, C.Y.; Devaraj, N.K. Site-Specific Covalent Labeling of RNA by Enzymatic Transglycosylation. Journal of the American Chemical Society, 2015, 137(40), 12756–12759. doi: 10.1021/jacs.5b07286
  19. Barlow, N.; Nasser, Y.; Zhao, P.; Sharma, N.; Guerrero-Alba, R.; Edgington-Mitchell, L.E.; Lieu, T.; Veldhuis, N.A.; Poole, D.P.; Conner, J.W.; Lindström, E.; Craig, A.W.; Graham, B.; Vanner, S.J.; Bunnett, N.W. Demonstration of elevated levels of active cathepsin S in dextran sulfate sodium colitis using a new activatable probe. Neurogastroenterology and Motility, 2015, 27(11), 1675–1680. doi: 10.1111/nmo.12656
  20. Gao, D.; Zhang, P.; Liu, C.; Chen, C.; Gao, G.; Wu, Y.; Sheng, Z.; Song, L.; Cai, L. Compact chelator-free Ni-integrated CuS nanoparticles with tunable near-infrared absorption and enhanced relaxivity for in vivo dual-modal photoacoustic/MR imaging. Nanoscale, 2015, 7, 17631–17636. doi: 10.1039/C5NR05237H
  21. Albertazzi, L.; van der Veeken, N.; Baker, M.B.; Palmans, A.R.A.; Meijer, E.W. Supramolecular copolymers with stimuli-responsive sequence control. Chemical Communications, 2015, 51(90), 16166–16168. doi: 10.1039/c5cc06951c
  22. Demillo, V.G.; Zhu, X. Zwitterionic amphiphile coated magnetofluorescent nanoparticles – synthesis, characterization and tumor cell targeting. Journal of Materials Chemistry B, 2015, 3, 8328–8336. doi: 10.1039/C5TB01116G
  23. Wang, C.; Wang, Y.; Li, Y.; Bodemann, B.; Zhao, T.; Ma, X.; Huang, G.; Hu, Z.; DeBerardinis, R.J.; White, M.A.; Gao, J. A nanobuffer reporter library for fine-scale imaging and perturbation of endocytic organelles. Nature Communications, 2015, 6, 8524. doi: 10.1038/ncomms9524
  24. Zhou, B.; Wang, H.; Liu, R.; Wang, M.; Deng, H.; Giglio, B.; Gill, P.S.; Shan, H.; Li, Z. PET Imaging of Dll4 Expression in Glioblastoma and Colorectal Cancer Xenografts Using 64Cu-Labeled Monoclonal Antibody 61B. Molecular Pharmaceutics, 2015, 12(10), 3527–3534. doi: 10.1021/acs.molpharmaceut.5b00105
  25. Yang, J.; Zhang, R.; Radford, D.C.; Kopeček, J. FRET-trackable biodegradable HPMA copolymer-epirubicin conjugates for ovarian carcinoma therapy. Journal of Controlled Release, 2015, 218, 36–44. doi: 10.1016/j.jconrel.2015.09.045
  26. Fuchs, A.V.; Tse, B.W.C.; Pearce, A.K.; Yeh, M.-C.; Fletcher, N.L.; Huang, S.S.; Heston, W.D.; Whittaker, A.K.; Russell, P.J.; Thurecht, K.J. Evaluation of Polymeric Nanomedicines Targeted to PSMA: Effect of Ligand on Targeting Efficiency. Biomacromolecules, 2015, 16(10), 3235–3247. doi: 10.1021/acs.biomac.5b00913
  27. Abolmaali, S.; Tamaddon, A.; Kamali-Sarvestani, E.; Ashraf, M.; Dinarvand, R. Stealth Nanogels of Histinylated Poly Ethyleneimine for Sustained Delivery of Methotrexate in Collagen-Induced Arthritis Model. Pharmaceutical Research, 2015, 32(10), 3309–3323. doi: 10.1007/s11095-015-1708-0
  28. Yu, Q.; Wei, Z.; Shi, J.; Guan, S.; Du, N.; Shen, T.; Tang, H.; Jia, B.; Wang, F.; Gan, Z. Polymer-Doxorubicin Conjugate Micelles Based on Poly(ethylene glycol) and Poly(N-(2-hydroxypropyl) methacrylamide): Effect of Negative Charge and Molecular Weight on Biodistribution and Blood Clearance. Biomacromolecules, 2015, 16(9), 2645–2655. doi: 10.1021/acs.biomac.5b00460
  29. Schwarz, B.; Madden, P.; Avera, J.; Gordon, B.; Larson, K.; Miettinen, H.; Uchida, M.; LaFrance, B.; Basu, G.; Rynda-Apple, A.; Douglas, T. Symmetry Controlled, Genetic Presentation of Bio-Active Proteins on the P22 Virus-Like Particle Using an External Decoration Protein. ACS Nano, 2015, 9(9), 9134–9147. doi: 10.1021/acsnano.5b03360
  30. Bruckman, M.; Randolph, L.; Gulati, N.; Stewart, P.; Steinmetz, N.F. Silica mineralization of Gd(DOTA)-loaded viral nanoparticles enhances MRI relaxivity and avoids immune recognition. Journal of Materials Chemistry B, 2015, 3(38), 7503–7510. doi: 10.1039/c5tb01014d
  31. Terekhov, S., Smirnov, I.; Bobik, T.; Shamborant, O.; Zenkova, M.; Chernolovskaya, E.; Gladkikh, D.; Murashev, A.; Dyachenko, I.; Palikov, V.; Palikova, Y.; Knorre, V.; Belogurov Jr, A.; Ponomarenko, N.; Blackburn, G.M.; Masson, P.; Gabibov, A. A novel expression cassette delivers efficient production of exclusively tetrameric human butyrylcholinesterase with improved pharmacokinetics for protection against organophosphate poisoning. Biochimie, 2015, 118, 51–59. doi: 10.1016/j.biochi.2015.07.028
  32. Vanparijs, N.; De Coen, R.; Laplace, D.R.; Louage, B.; Maji, S.; Lybaert, L.; Hoogenboom, R.; De Geest, B. Transiently responsive protein-polymer conjugates via a grafting-from RAFT approach: for intracellular co-delivery of proteins and immune-modulators. Chemical Communications, 2015, 51, 13972–13975. doi: 10.1039/c5cc04809e
  33. Chen, L.; An, H.; Doyle, P.S. Synthesis of non-spherical microcapsules through controlled polyelectrolyte coating of hydrogel templates. Langmuir, 2015, 31(33), 9228–9235. doi: 10.1021/acs.langmuir.5b02200
  34. Li, H.; Yang, Z.-Y.; Liu, C.; Zeng, Y.-P.; Hao, Y.-H. Gu, Y.; Wang, W.-D.; Li, R. PEGylated ceria nanoparticles used for radioprotection on Human liver cells under γ-ray irradiation. Free Radical Biology and Medicine, 2015, 87, 26–35. doi: 10.1016/j.freeradbiomed.2015.06.010
  35. Geng, L.; Wang, Z.; Yang, X.; Li, D.; Lian, W.; Xiang, Z.; Wang, W.; Bu, X.; Lai, W.; Hu, Z.; Fang, Q. Structure-based Design of Peptides with High Affinity and Specificity to HER2 Positive Tumors. Theranostics, 2015, 5(10), 1154–1165. doi: 10.7150/thno.12398
  36. Schmidt, W.M.; Lehman, W.; Moore, J.R. Direct observation of tropomyosin binding to actin filaments. Cytoskeleton, 2015, 72(6), 292–303. doi: 10.1002/cm.21225
  37. Stone, R.C.; Fellows, B.D.; Qi, B.; Trebatowski, D.; Jenkins, B.; Raval, Y.; Tzeng, T.R.; Bruce, T.F.; Mcnealy, T.; Austin, M.J.; Monson, T.C.; Huber, D.L.; Mefford, O.T. Highly Stable Multi-Anchored Magnetic Nanoparticles for Optical Imaging within Biofilms. Journal of Colloid and Interface Science, 2015, 459, 175–182. doi: 10.1016/j.jcis.2015.08.012
  38. Chung, S.W.; Lee, B.S. Choi, J.U.; Kim, S.W.; Kim, I.-S.; Kim, S.Y.; Byun, Y. Optimization of a stable linker involved DEVD peptide-doxorubicin conjugate that is activated upon radiation-induced caspase-3-mediated apoptosis. Journal of Medicinal Chemistry, 2015, 58(16), 6435–6447. doi: 10.1021/acs.jmedchem.5b00420
  39. Li, X.-P.; Jing, W.; Sun, J.-J.; Liu, Z.-Y.; Zhang, J.-T.; Sun, W.; Zhu, W.; Fan, Y.-Z. A potential small-molecule synthetic antilymphangiogenic agent norcantharidin inhibits tumor growth and lymphangiogenesis of human colonic adenocarcinomas through blocking VEGF-A,-C,-D/VEGFR-2,-3 "multi-points priming" mechanisms in vitro and ... BMC Cancer, 2015, 15, 527. doi: 10.1186/s12885-015-1521-5
  40. Ilnitskaya, E.V.; Kononevich, Y.N.; Muzafarov, A.M.; Rzhevskiy, S.A.; Shadrin, I.A.; Babaev, E.V.; Martynov, V.I.; Pakhomov, A.A. Preparation and application of a BODIPY-labeled probe for a real-time polymerase chain reaction. Russian Journal of Bioorganic Chemistry, 2015, 41(4), 451–453. doi: 10.1134/S1068162015040068
  41. Park, H.-K.; Lee, S.J.; Oh, J.-S.; Lee, S.-G.; Jeong, Y.-I.; Lee, H.C. Smart Nanoparticles Based on Hyaluronic Acid for Redox-Responsive and CD44 Receptor-Mediated Targeting of Tumor. Nanoscale Research Letters, 2015, 10(1), 981. doi: 10.1186/s11671-015-0981-5
  42. Guo, Y.; Wang, D.; Song, Q.; Wu, T.; Zhuang, X.; Bao, Y.; Kong, M.; Qi, Y.; Tan, S.; Zhang, Z. Erythrocyte Membrane-Enveloped Polymeric Nanoparticles as Nanovaccine for Induction of Antitumor Immunity against Melanoma. ACS Nano, 2015, 9(7), 6918–6933. doi: 10.1021/acsnano.5b01042
  43. Shi, Q.; Zhang, L.; Liu, M.; Zhang, X.; Zhang, X.; Xu, X.; Chen, S.; Li, X.; Zhang, J. Reversion of multidrug resistance by a pH-responsive cyclodextrin-derived nanomedicine in drug resistant cancer cells. Biomaterials, 2015, 67, 169–182. doi: 10.1016/j.biomaterials.2015.07.023
  44. Søndergaard, S.; Aznauryan, M.; Haustrup, E.K.; Schiøtt, B.; Birkedal, V.; Corry, B. Dynamics of Fluorescent Dyes Attached to G-Quadruplex DNA and their Effect on FRET Experiments. ChemPhysChem, 2015, 16(12), 2562–2570. doi: 10.1002/cphc.201500271
  45. Lu, J.; Zhou, Z.; Zheng, J.; Zhang, Z.; Lu, R.; Liu, H.; Shi, H.; Tu, Z. 2D-DIGE and MALDI TOF/TOF MS analysis reveal that small GTPase signaling pathways may play an important role in cadmium-induced colon cell malignant transformation. Toxicology and Applied Pharmacology, 2015, 288(1), 106–113. doi: 10.1016/j.taap.2015.07.020
  46. Fu, B.; Flynn, J.D.; Isaacoff, B.P.; Rowland, D.J.; Biteen, J.S. Super-Resolving the Distance-Dependent Plasmon-Enhanced Fluorescence of Single Dye and Fluorescent Protein Molecules. The Journal of Physical Chemistry C, 2015, 119(33), 19350–19358. doi: 10.1021/acs.jpcc.5b05154
  47. Klykov, O.; Weller, M.G. Quantification of N-hydroxysuccinimide and N-hydroxysulfosuccinimide by hydrophilic interaction chromatography (HILIC). Analytical Methods, 2015, 7, 6443–6448. doi: 10.1039/c5ay00042d
  48. Li, L.; Sun, W.; Zhong, J.; Yang, Qi.; Zhu, X.; Zhou, Z.; Zhang Z.; Huang, Y. Multistage Nanovehicle Delivery System Based on Stepwise Size Reduction and Charge Reversal for Programmed Nuclear Targeting of Systemically Administered Anticancer Drugs. Advanced Functional Materials, 2015, 25(26), 4101–4113. doi: 10.1002/adfm.201501248
  49. Zhong, J.; Li, L.; Zhu, X.; Guan, S.; Yang, Q.; Zhou, Z.; Zhang, Z.; Huang, Y. A smart polymeric platform for multistage nucleus-targeted anticancer drug delivery. Biomaterials, 2015, 65, 43–55. doi: 10.1016/j.biomaterials.2015.06.042
  50. Zhou, J.; Joshi, B.P.; Duan, X.; Pant, A.; Qiu, Z.; Kuick, R.; Owens, S.R.; Wang, T.D. EGFR Overexpressed in Colonic Neoplasia Can be Detected on Wide-Field Endoscopic Imaging. Clinical and Translational Gastroenterology, 2015, 6, e101. doi: 10.1038/ctg.2015.28
  51. Ma, Y.; Fuchs, A.; Boase, N.R.B.; Rolfe, B.E.; Coombes, A.G.A.; Thurecht, K.J. The in vivo fate of nanoparticles and nanoparticle-loaded microcapsules after oral administration in mice: evaluation of their potential for colon-specific delivery. European Journal of Pharmaceutics and Biopharmaceutics, 2015, 94, 393–403. doi: 10.1016/j.ejpb.2015.06.014
  52. Vega, B.; Wondraczek, H.; Bretschneider, L.; Näreoja, T.; Fardim, P.; Heinze, T. Preparation of reactive fibre interfaces using multifunctional cellulose derivatives. Carbohydrate Polymers, 2015, 132, 261–273. doi: 10.1016/j.carbpol.2015.05.048
  53. Chuang, E.-Y.; Lin, K.-J.; Lin, P.-Y. Chen, H.-L. Wey, S.-P. Mi, F.-L. Hsiao, H.-C. Chen, C.-T.; Sung, H.-W. Self-Assembling Bubble Carriers for Oral Protein Delivery. Biomaterials, 2015, 64, 115–124. doi: 10.1016/j.biomaterials.2015.06.035
  54. Huang, X.; He, J.; Hao, Y.; Ye, M.; Zhang, Q.; Ni, P.; Liu, J. Synthesis of PEGylated brush-type copolymers for a plurality of plug-and-play functions. RSC Advances, 2015, 5(62), 50019–50023. doi: 10.1039/c5ra06484h
  55. Mohan, K.; Penner, R.M.; Weiss, G.A. Biosensing with Virus Electrode Hybrids. Current Protocols in Chemical Biology, 2015, 7, 53–73. doi: 10.1002/9780470559277.ch140213
  56. Wilks, M.Q.; Normandin, M.D.; Yuan, H.; Cho, H.; Guo, Y.; Herisson, F.; Ayata, C.; Wooten, D.W.; El Fakhri, G.; Josephson, L. Imaging PEG-Like Nanoprobes in Tumor, Transient Ischemia, and Inflammatory Disease Models. Bioconjugate Chemistry, 2015, 26(6), 1061–1069. doi: 10.1021/acs.bioconjchem.5b00213
  57. Wanat, P.; Walczak, S.; Wojtczak, B.A.; Nowakowska, M.; Jemielity, J.; Kowalska, J. Ethynyl, 2-Propynyl, and 3-Butynyl C-Phosphonate Analogues of Nucleoside Di- and Triphosphates: Synthesis and Reactivity in CuAAC. Organic Letters, 2015, 17(12), 3062–3065. doi: 10.1021/acs.orglett.5b01346
  58. Han, F.Y.; Thurecht, K.J.; Lam, A.-L.; Whittaker, A.K.; Smith, M.T. Novel Polymeric Bioerodable Microparticles for Prolonged-Release Intrathecal Delivery of Analgesic Agents for Relief of Intractable Cancer-Related Pain. Journal of Pharmaceutical Sciences, 2015, 104(7), 2334–2344. doi: 10.1002/jps.24497
  59. Noriega, R.; Finley, D.T.; Haberstroh, J.; Geissler, P.L.; Francis, M.B.; Ginsberg, N.S. Manipulating Excited-State Dynamics of Individual Light-Harvesting Chromophores through Restricted Motions in a Hydrated Nanoscale Protein Cavity. The Journal of Physical Chemistry B, 2015, 119(23), 6963–6973. doi: 10.1021/acs.jpcb.5b03784
  60. Maity, A.; Macaubas, C.; Mellins, E.; Astakhova, K. Synthesis of Phospholipid-Protein Conjugates as New Antigens for Autoimmune Antibodies. Molecules, 2015, 20(6), 10253–10263. doi: 10.3390/molecules200610253
  61. Singh, S.; Pal, K.; Yadav, J.; Tang, H.; Partyka, K.; Kletter, D.; Hsueh, P.; Ensink, E.; KC, B.; Hostetter, G.; Xu, H.E.; Bern, M.; Smith, D.F.; Mehta, A.S.; Brand, R.; Melcher, K.; Haab, B.B. Upregulation of Glycans Containing 3' Fucose in a Subset of Pancreatic Cancers Uncovered Using Fusion-Tagged Lectins. Journal of Proteome Research, 2015, 14(6), 2594–2605. doi: 10.1021/acs.jproteome.5b00142
  62. Printz, B.; Guerriero, G.; Sergeant, K.; Renaut, J.; Lutts, S.; Hausman, J.-F. Ups and downs in alfalfa: Proteomic and metabolic changes occurring in the growing stem. Plant Science, 2015, 238, 13–25. doi: 10.1016/j.plantsci.2015.05.014
  63. Unciti-Broceta, J.D.; Cano-Cortés, V.; Altea-Manzano, P.; Pernagallo, S.; Díaz-Mochón, J.J.; Sánchez-Martín, R.M. Number of Nanoparticles per Cell through a Spectrophotometric Method – A key parameter to Assess Nanoparticle-based Cellular Assays. Scientific Reports, 2015, 5, 10091. doi: 10.1038/srep10091
  64. Han, Z.; Zhou, Z.; Shi, X.; Wang, J.; Wu, X.; Sun, D.; Chen, Y.; Zhu, H.; Magi-Galluzzi, C.; Lu, Z.-R. EDB fibronectin specific peptide for prostate cancer targeting. Bioconjugate Chemistry, 2015, 26(5), 830–838. doi: 10.1021/acs.bioconjchem.5b00178
  65. Medina, S.H.; Schneider, J.P. Cancer cell surface induced peptide folding allows intracellular translocation of drug. Journal of Controlled Release, 2015, 209, 317–326. doi: 10.1016/j.jconrel.2015.05.267
  66. Mwangi, T.K.; Bowles, R.D.; Tainter, D.M.; Bell, R.D.; Kaplan, D.L.; Setton, L.A. Synthesis and characterization of silk fibroin microparticles for intra-articular drug delivery. International Journal of Pharmaceutics, 2015, 485(1–2), 7–14. doi: 10.1016/j.ijpharm.2015.02.059
  67. Wade, R.J.; Bassin, E.J.; Rodell, C.B.; Burdick, J.A. Protease-degradable electrospun fibrous hydrogels. Nature Communications, 2015, 6, 6639. doi: 10.1038/ncomms7639
  68. Bygd, H.C.; Forsmark, K.D.; Bratlie, K.M. Altering in vivo macrophage responses with modified polymer properties. Biomaterials, 2015, 56, 187–197. doi: 10.1016/j.biomaterials.2015.03.042
  69. Deyle, K.M.; Farrow, B.; Hee, Y.Q.; Work, J.; Wong, M.; Lai, B.; Umeda, A.; Millward, S.W.; Nag, A.; Das, S.; Heath, J.R. A protein-targeting strategy used to develop a selective inhibitor of the E17K point mutation in the PH domain of Akt1. Nature Chemistry, 2015, 7, 455–462. doi: 10.1038/nchem.2223
  70. Nikić, I.; Kang, J.H.; Girona, G.E.; Aramburu, I.V.; Lemke, E.A. Labeling proteins on live mammalian cells using click chemistry. Nature Protocols, 2015, 10(5), 780–791. doi: 10.1038/nprot.2015.045
  71. Wang, W.; Kapur, A.; Ji, X.; Safi, M.; Palui, G.; Palomo, V.; Dawson, P.E.; Mattoussi, H. Photoligation of an Amphiphilic Polymer with Mixed Coordination Provides Compact and Reactive Quantum Dots. Journal of the American Chemical Society, 2015, 137(16), 5438–5451. doi: 10.1021/jacs.5b00671
  72. Nåbo, L.J.; Madsen, C.S.; Jensen, K.J.; Kongsted, J.; Astakhova, K. Ultramild Protein-Mediated Click Chemistry Creates Efficient Oligonucleotide Probes for Targeting and Detecting Nucleic Acids. ChemBioChem, 2015, 16(8), 1163–1167. doi: 10.1002/cbic.201500145
  73. Saadat, E.; Shakor, N.; Gholami, M.; Dorkoosh, F.A. Hyaluronic acid based micelle for articular delivery of triamcinolone, preparation, in vitro and in vivo evaluation. International Journal of Pharmaceutics, 2015, 489(1–2), 218–225. doi: 10.1016/j.ijpharm.2015.05.001
  74. Reid, D.A.; Keegan, S.; Leo-Macias, A.; Watanabe, G.; Strande, N.T.; Chang, H.H.; Oksuz, B.A.; Fenyo, D.; Lieber, M.R.; Ramsden, D.A.; Rothenberg, E. Organization and dynamics of the nonhomologous end-joining machinery during DNA double-strand break repair. Proceedings of the National Academy of Sciences of the U.S.A., 2015, 112(20), E2575–E2584. doi: 10.1073/pnas.1420115112
  75. Hou, Z.; Lin, J.; Li, Y.; Guo, F.; Yu, F.; Wu, H.; Fan, Z.; Zhi, L.; Luo, F. Validation of a dual role of methotrexate-based chitosan nanoparticles in vivo. RSC Advances, 2015, 5(52), 41393–41400. doi: 10.1039/c5ra03705K
  76. Ruan, S.; He, Q.; Gao, H. Matrix metalloproteinase triggered size-shrinkable gelatin-gold fabricated nanoparticles for tumor microenvironment sensitive penetration and diagnosis of glioma. Nanoscale, 2015, 7, 9487–9496. doi: 10.1039/c5nr01408e
  77. Shi, Y.; van der Meel, R.; Theek, B.; Oude Blenke, E.; Pieters, E.H.E.; Fens, M.H.A.M.; Ehling, J.; Schiffelers, R.M.; Storm, G.; van Nostrum, C.F.; Lammers, T.; Hennink, W.E. Complete Regression of Xenograft Tumors upon Targeted Delivery of Paclitaxel via Π–Π Stacking Stabilized Polymeric Micelles. ACS Nano, 2015, 9(4), 3740–3752. doi: 10.1021/acsnano.5b00929
  78. Baker, Matthew B. and Albertazzi, Lorenzo and Voets, Ilja K. and Leenders, Christianus M.A. and Palmans, Anja R.A. and Pavan, Giovanni M. and Meijer, E.W. Consequences of chirality on the dynamics of a water-soluble supramolecular polymer. Nature Communications, 2015, 6, 6234. doi: 10.1038/ncomms7234
  79. Rammohan, J.; Ruiz Manzano, A.; Garner, A.L.; Stallings, C.L.; Galburt, E.A. CarD stabilizes mycobacterial open complexes via a two-tiered kinetic mechanism. Nucleic Acids Research, 2015, 43(6), 3272–3285. doi: 10.1093/nar/gkv078
  80. Li, F.; Dong, J.; Hu, X.; Gong, W.; Li, J.; Shen, J.; Tian, H.; Wang, J. A Covalent Approach for Site-Specific RNA Labeling in Mammalian Cells. Angewandte Chemie International Edition, 2015, 54(15), 4597–4602. doi: 10.1002/anie.201410433
  81. Zilio, C.;Bernardi, A.; Palmioli, A.; Salina, M.; Tagliabue, G.; Buscaglia, M.; Consonni, R.; Chiari, M. New "clickable" polymeric coating for glycan microarrays. Sensors and Actuators B: Chemical, 2015, 215, 412–420. doi: 10.1016/j.snb.2015.03.079
  82. Maruani, A.; Smith, M.E.B.; Miranda, E.; Chester, K.A.; Chudasama, V.; Caddick, S. A plug-and-play approach to antibody-based therapeutics via a chemoselective dual click strategy. Nature communications, 2015, 6, 6645. doi: 10.1038/ncomms7645
  83. Arami, H.; Khandhar, A.P.; Tomitaka, A.; Yu, E.; Goodwill, P.W.; Conolly, S.M.; Krishnan, K.M. In vivo multimodal magnetic particle imaging (MPI) with tailored magneto/optical contrast agents. Biomaterials, 2015, 52, 251–261. doi: 10.1016/j.biomaterials.2015.02.040
  84. Huang, J.; Smith, F.; Panizzi, J.R.; Goodwin, D.C.; Panizzi, P. Inactivation of myeloperoxidase by benzoic acid hydrazide. Archives of Biochemistry and Biophysics, 2015, 570, 14–22. doi: 10.1016/j.abb.2015.01.028
  85. Mahoney, D.; Owens, E.A.; Fan, C.; Hsiang, J.-C.; Henary, M.; Dickson, R.M. Tailoring Cyanine Dark States for Improved Optically Modulated Fluorescence Recovery. The Journal of Physical Chemistry B, 2015, 119(13), 4637–4643. doi: 10.1021/acs.jpcb.5b00777
  86. Rodell, C.B.; Wade, R.J.; Purcell, B.P.; Dusaj, N.N.; Burdick, J.A. Selective Proteolytic Degradation of Guest–Host Assembled, Injectable Hyaluronic Acid Hydrogels. ACS Biomaterials Science & Engineering, 2015, 1(4), 277–286. doi: 10.1021/ab5001673
  87. Rodell, C.B.; Rai, R.; Faubel, S.; Burdick, J.A.; Soranno, D.E. Local Immunotherapy via Delivery of Interleukin-10 and Transforming Growth Factor β Antagonist for Treatment of Chronic Kidney Disease. Journal of Controlled Release, 2015, 206, 131–139. doi: 10.1016/j.jconrel.2015.03.025
  88. Hörner, A.; Hagendorn, T.; Schepers, U.; Bräse, S. Photophysical properties and synthesis of new dye-cyclooctyne conjugates for multicolor and advanced microscopy. Bioconjugate Chemistry, 2015, 26(4), 718–724. doi: 10.1021/acs.bioconjchem.5b00059
  89. Leonard, J.D.; Narlikar, G.J. A Nucleotide-Driven Switch Regulates Flanking DNA Length Sensing by a Dimeric Chromatin Remodeler. Molecular Cell, 2015, 57(5), 850–859. doi: 10.1016/j.molcel.2015.01.008
  90. Kim, M.-G.; Park, J.Y.; Miao, W.; Lee, J.; Oh, Y.-K. Polyaptamer DNA nanothread-anchored, reduced graphene oxide nanosheets for targeted delivery. Biomaterials, 2015, 48, 129–136. doi: 10.1016/j.biomaterials.2015.01.009
  91. Lee, S.J.; Shim, Y.H.; Oh, J.-S.; Jeong, Y.-I. Park, I.-K.; Lee, H.C. Folic-acid-conjugated pullulan/poly(DL-lactide-co-glycolide) graft copolymer nanoparticles for folate-receptor-mediated drug delivery. Nanoscale Research Letters, 2015, 10, 43. doi: 10.1186/s11671-014-0706-1
  92. Ashoub, A.; Baeumlisberger, M.;Neupaertl, M.; Karas, M.; Brüggemann, W. Characterization of common and distinctive adjustments of wild barley leaf proteome under drought acclimation, heat stress and their combination. Plant Molecular Biology, 2015, 87(4–5), 459–471. doi: 10.1007/s11103-015-0291-4
  93. Cai, H.; Singh, A.N.; Sun, X.; Peng, F. Synthesis and Characterization of Her2-NLP Peptide Conjugates Targeting Circulating Breast Cancer Cells: Cellular Uptake and Localization by Fluorescent Microscopic Imaging. Journal of Fluorescence, 2015, 25(1), 113–117. doi: 10.1007/s10895-014-1486-9
  94. Yang, Q.; Li, L.; Zhu, X.; Sun, W.; Zhou, Z.; Huang, Y. The impact of the HPMA polymer structure on the targeting performance of the conjugated hydrophobic ligand. RSC Advances, 2015, 5(19), 14858–14870. doi: 10.1039/c4ra16085a
  95. Aldeek, F.; Hawkins, D.; Palomo, V.; Safi, M.; Palui, G.; Dawson, P.E.; Alabugin, I.V.; Mattoussi, H. UV and Sunlight Driven Photoligation of Quantum Dots: Understanding the Photochemical Transformation of the Ligands. Journal of the American Chemical Society, 2015, 137(7), 2704–2714. doi: 10.1021/ja512802x
  96. Cai, L.; Dewi, R.E.; Heilshorn, S.C. Injectable Hydrogels with In Situ Double Network Formation Enhance Retention of Transplanted Stem Cells. Advanced Functional Materials, 2015, 25(9), 1344–1351. doi: 10.1002/adfm.201403631
  97. Duong, H.T.T.; Dong, Z.; Su, L; Boyer, C.; George, J.; Davis, T.P.; Wang, J. The Use of Nanoparticles to Deliver Nitric Oxide to Hepatic Stellate Cells for Treating Liver Fibrosis and Portal Hypertension. Small, 2015, 11(19), 2291–2304. doi: 10.1002/smll.201402870
  98. Pereira, P.M.; Almada, P.; Henriques, R. High-content 3D multicolor super-resolution localization microscopy. Methods in Cell Biology, 2015, 125, 95–117. doi: 10.1016/bs.mcb.2014.10.004
  99. Glembockyte, V.; Lincoln, R.; Cosa, G. Cy3 Photoprotection Mediated by Ni2+ for Extended Single-Molecule Imaging: Old Tricks for New Techniques. Journal of the American Chemical Society, 2015, 137(3), 1116–1122. doi: 10.1021/ja509923e
  100. Wen, A.M.; Infusino, M.; De Luca, A.; Kernan, D.L.; Czapar, A.E.; Strangi, G.; Steinmetz, N.F. Interface of Physics and Biology: Engineering Virus-Based Nanoparticles for Biophotonics. Bioconjugate Chemistry, 2015, 26(1), 51–62. doi: 10.1021/bc500524f
  101. Nakamura, T.; Sugihara, F.; Matsushita, H.; Yoshioka, Y.; Mizukami, S.; Kikuchi, K. Mesoporous silica nanoparticles for 19F magnetic resonance imaging, fluorescence imaging, and drug delivery. Chemical Science, 2015, 6, 1986–1990. doi: 10.1039/c4sc03549f
  102. Brauer, V.S.; Stomp, M.; Bouvier, T.; Fouilland, E.; Leboulanger, C.; Confurius-Guns, V.; Weissing, F.J.; Stal, L.J.; Huisman, J. Competition and facilitation between the marine nitrogen-fixing cyanobacterium Cyanothece and its associated bacterial community. Frontiers in Microbiology, 2015, 5, 795. doi: 10.3389/fmicb.2014.00795
  103. Zhang, J.; Wang, G.; Mao, D.; Han, A.; Xiao, N.; Qi, X.; Ding, D.; Kong, D. Targeted In Vivo Imaging of Mouse Hindlimb Ischemia Using Fluorescent Gelatin Nanoparticles. Journal of Nanomaterials, 2015, 2015, Article ID 704817. doi: doi.org/10.1155/2015/704817
  104. Hsueh, P.-Y.; Edman, M.C.; Sun, G.; Shi, P.; Xu, S.; Lin, Y.-a.; Cui, H.; Hamm-Alvarez, S.F.; MacKay, J.A. Tear-mediated delivery of nanoparticles through transcytosis of the lacrimal gland. Journal of Controlled Release, 2015, 208, 2–13. doi: 10.1016/j.jconrel.2014.12.017
  105. Chiang, W.-L.; Lin, T.-T.; Sureshbabu, R.; Chia, W.-T.; Hsiao, H.-C.; Liu, H.-Y.; Yang, C.-M.; Sung, H.-W. A rapid drug release system with a NIR light-activated molecular switch for dual-modality photothermal/antibiotic treatments of subcutaneous abscesses. Journal of Controlled Release, 2015, 199, 53–62. doi: 10.1016/j.jconrel.2014.12.011
  106. Popp, M.W. Site-Specific Labeling of Proteins via Sortase: Protocols for the Molecular Biologist. Methods in Molecular Biology, 2015, 1266, 185–198. doi: 10.1007/978-1-4939-2272-7_13
  107. Choi, E.B.; Choi, J.; Bae, S.R.; Kim, H.-O.; Jang, E.; Kang, B.; Kim, M.-H.; Kim, B.; Suh, J.-S.; Lee, K. et al. Colourimetric redox-polyaniline nanoindicator for in situ vesicular trafficking of intracellular transport. Nano Research, 2015, 8(4), 1169–1179. doi: 10.1007/s12274-014-0597-6
  108. Maruani, A.; Alom, S.; Canavelli, P.; Lee, M.T.W.; Morgan, R.E.; Chudasama, V.; Caddick, S. A mild TCEP-based para-azidobenzyl cleavage strategy to transform reversible cysteine thiol labelling reagents into irreversible conjugates. Chemical Communications, 2015, 51, 5279–5282. doi: 10.1039/c4cc08515a
  109. Geertsema, H.J.; Duderstadt, K.E.; van Oijen, A.M. Single-molecule observation of prokaryotic DNA replication. Methods in Molecular Biology, 2015, 1300, 219–238. doi: 10.1007/978-1-4939-2596-4_14
  110. Wei, S.; Shalhout, S.; Ahn, Y.-H.; Bhagwat, A.S. A Versatile New Tool to Quantify Abasic Sites in DNA and Inhibit Base Excision Repair. DNA Repair, 2015, 27, 9–18. doi: doi:10.1016/j.dnarep.2014.12.006
  111. Jeong, J.-H. Molecular imaging monitoring of poly(ethylene glycol) conjugated islets for evaluation of islet graft rejection. Archives of Pharmacal Research, 2015, 38(5), 785–790. doi: 10.1007/s12272-014-0412-7
  112. Nooney, R.I.; White, A.; O’Mahony, C.; O’Connell, C.; Kelleher, S.M.; Daniels, S.; McDonagh, C. Investigating the colloidal stability of fluorescent silica nanoparticles under isotonic conditions for biomedical applications. Journal of Colloid and Interface Science, 2015, 456, 50–58. doi: 10.1016/j.jcis.2015.05.051
  113. Guenther, D.; Anderson, G.; Karmakar, S.; Anderson, B.A.; Didion, B.A.; Guo, W.; Verstegen, J.; Hrdlicka, P.J. Invader probes: Harnessing the energy of intercalation to facilitate recognition of chromosomal DNA for diagnostic applications. Chemical Science, 2015, 6, 5006–2015. doi: 10.1039/c5sc01238d
  114. Nooney, R.; O’Connell, C.; Roy, S.; Boland, K.; Keegan, G.; Kelleher, S.; Daniels, S.; McDonagh, C. Synthesis and characterisation of far-red fluorescent cyanine dye doped silica nanoparticles using a modified microemulsion method for application in bioassays. Sensors and Actuators B: Chemical, 2015, 221, 470–479. doi: 10.1016/j.snb.2015.06.117
  115. Lipchik, A.M.; Perez, M.; Cui, W.; Parker, L.L. Multicolored, Tb3+-Based Antibody-Free Detection of Multiple Tyrosine Kinase Activities. Analytical Chemistry, 2015, 87(15), 7555–7558. doi: 10.1021/acs.analchem.5b02233
  116. Tucker, K.R.; Block, E.R.; Levitan, E.S. Action potentials and amphetamine release antipsychotic drug from dopamine neuron synaptic VMAT vesicles. Proceedings of the National Academy of Sciences of the U.S.A., 2015, 112(32), E4485–E4494. doi: 10.1073/pnas.1503766112
  117. Zhang, Z.; Kenny, S.J.; Hauser, M.; Li, W.; Xu, K. Ultrahigh-throughput single-molecule spectroscopy and spectrally resolved super-resolution microscopy. Nature Methods, 2015, 12(10), 935–938. doi: 10.1038/nmeth.3528
  118. Martell, D.J.; Joshi, C.P.; Gaballa, A.; Santiago, A.G.; Chen, T.-Y.; Jung, W.; Helmann, J.D.; Chen, P. Metalloregulator CueR biases RNA polymerase's kinetic sampling of dead-end or open complex to repress or activate transcription. Proceedings of the National Academy of Sciences of the U.S.A., 2015, 112(44), 13467–13472. doi: 10.1073/pnas.1515231112
  119. Chen, K.; Xu, X.; Guo, J.W.; Zhang, X.; Han, S.; Wang, R.; Li, X.; Zhang, J. Enhanced Intracellular Delivery and Tissue Retention of Nanoparticles by Mussel-Inspired Surface Chemistry. Biomacromolecules, 2015, 16(11), 3574–3583. doi: 10.1021/acs.biomac.5b01056
  120. Einfalt, T.; Goers, R.; Dinu, I.A.; Najer, A.; Spulber, M.; Onaca-Fischer, O.; Palivan, C.G. Stimuli-triggered activity of nanoreactors by biomimetic engineering polymer membranes. Nano Letters, 2015, 15(11), 7596–7603. doi: 10.1021/acs.nanolett.5b03386
  121. Mohan, K.; Weiss, G.A. Engineering chemically modified viruses for prostate cancer cell recognition. Molecular BioSystems, 2015, 11, 3264–3272. doi: 10.1039/c5mb00511f
  122. Junker, M.; Rapoport, T.A. Involvement of VAT-1 in phosphatidylserine transfer from the endoplasmic reticulum to mitochondria. Traffic, 2015, 16(12), 1306–1317. doi: 10.1111/tra.12336
  123. Santangelo, M.F.; Sciuto, E.L.; Busacca, A.C.; Petralia, S.; Conoci, S.; Libertino, S. SiPM as miniaturised optical biosensor for DNA-microarray applications. Sensing and Bio-Sensing Research, 2015, 6, 95–98. doi: 10.1016/j.sbsr.2015.08.003
  124. Sciuto, E.L.; Santangelo, M.F.; Villaggio, G.; Sinatra, F.; Bongiorno, C.; Nicotra, G.; Libertino, S. Photo-physical characterization of fluorophore Ru(bpy)32+ for optical biosensing applications. Sensing and Bio-Sensing Research, 2015, 6, 67–71. doi: 10.1016/j.sbsr.2015.09.003
  125. Dogandzhiyski, P.; Ghidini, A.; Danneberg, F.; Strömberg, R.; Göbel, M.W. Studies on Tris(2-aminobenzimidazole)-PNA Based Artificial Nucleases: A Comparison of Two Analytical Techniques. Bioconjugate Chemistry, 2015, 26(12), 2514–2519. doi: 10.1021/acs.bioconjchem.5b00534
  126. Kawamura, W.; Miura, Y.; Kokuryo, D.; Toh, K.; Yamada, N.; Nomoto, T.; Matsumoto, Y.; Sueyoshi, D.; Liu, X.; Aoki, I.; Kano, M.R.; Nishiyama, N.; Saga, T.; Kishimura, A.; Kataoka, K. Density-tunable conjugation of cyclic RGD ligands with polyion complex vesicles for the neovascular imaging of orthotopic glioblastomas. Science and Technology of Advanced Materials, 2015, 16(3), 035004. doi: 10.1088/1468-6996/16/3/035004

2014

  1. Hickey, S. F.; Hammond, M.C. Structure-Guided Design of Fluorescent S-Adenosylmethionine Analogs for a High-Throughput Screen to Target SAM-I Riboswitch RNAs. Chemistry & Biology, 2014, 21(3), 345–356. doi: 10.1016/j.chembiol.2014.01.004
  2. Wang, X.; Huang, S.S.; Heston, W.D.W.; Guo, H.; Wang, B.-C.; Basilion, J.P. Development of Targeted Near-Infrared Imaging Agents for Prostate Cancer. Molecular Cancer Therapeutics, 2014, 13(11), 2595–2606. doi: 10.1158/1535-7163.mct-14-0422
  3. Shieh, P.; Siegrist, M.S.; Cullen, A.J.; Bertozzi, C.R. Imaging bacterial peptidoglycan with near-infrared fluorogenic azide probes. Proceedings of the National Academy of Sciences of the U.S.A., 2014, 111(15), 5456–5461. doi: 10.1073/pnas.1322727111
  4. Bird, G.H., Boyapalle, S.; Wong, T.; Opoku-Nsiah, K.; Bedi, R.; Crannell, W.C.; Perry, A.F.; Nguyen, H.; Sampayo, V.; Devareddy, A.; Mohapatra, S.; Mohapatra S.S.; Walensky, L.D. Mucosal delivery of a double-stapled {RS}V peptide prevents nasopulmonary infection. Journal of Clinical Investigation, 2014, 124(5), 2113–2124. doi: 10.1172/jci71856
  5. Jia, L.; Chisari, M.; Maktabi, M.H.; Sobieski, C.; Zhou, H.; Konopko, A.M.; Martin, B.R.; Mennerick, S.J.; Blumer, K.J. A Mechanism Regulating G Protein-coupled Receptor Signaling That Requires Cycles of Protein Palmitoylation and Depalmitoylation. Journal of Biological Chemistry, 2014, 289(9), 6249–6257. doi: 10.1074/jbc.m113.531475
  6. Zhang, X.-N.; Zhang, C.-G.; Zhu, Q.-L.; Zhou, Y.; Liu, Y.; Chen, W.-L.; Yang, S.-D. Zhou, X.-F. Zhu, A.-J.; Zhang, X.-N.; Jin, Y. N-Succinyl-chitosan nanoparticles coupled with low-density lipoprotein for targeted osthole-loaded delivery to low-density lipoprotein receptor-rich tumors. International Journal of Nanomedicine, 2014, 9, 2919–2932. doi: 10.2147/ijn.s59799
  7. Abel, G.R.; Cao, B.H.; Hein, J.E.; Ye, T. Covalent, sequence-specific attachment of long {DNA} molecules to a surface using DNA-templated click chemistry. Chemical Communications, 2014, 50(60), 8131–8133. doi: 10.1039/c4cc02900c
  8. Basu, R.; Lai, L.-T.; Meng, Z.; Wu, J.; Shao, F.; Zhang, L.-F. Using Amino-Labeled Nucleotide Probes for Simultaneous Single Molecule RNA-DNA FISH. PLoS ONE, 2014, 9(9), e107425. doi: 10.1371/journal.pone.0107425
  9. Zhou, Y.; Guo, T.; Li, X.; Dong, Y.; Galatsis, P.; Johnson, D.S.; Pan, Z. Discovery of selective 2,4-diaminopyrimidine-based photoaffinity probes for glyoxalase I. Medicinal Chemistry Communications, 2014, 5(3), 352–357. doi: 10.1039/c3md00286a
  10. Terekhov, S.S.; Smirnov, I.V.; Shamborant, O.G.; Zenkova, M.A.; Chernolovskaya, E.L.; Gladkikh, D.V.; Murashev, A.N.; Dyachenko, I.A.; Knorre, V.D.; Belogurov, A.A.; Ponomarenko, N.A.; Deyev, S.M.; Vlasov, V.V.; Gabibov, A.G. Excessive Labeling Technique Provides a Highly Sensitive Fluorescent Probe for Real-time Monitoring of Biodegradation of Biopolymer Pharmaceuticals in vivo. Acta Naturae, 2014, 6(4), 54–59
  11. Okholm, A.; Kjems, J.; Astakhova, K. Fluorescence detection of natural RNA using rationally designed "clickable" oligonucleotide probes. RSC Advances, 2014, 4(86), 45653–45656. doi: 10.1039/c4ra07165d
  12. Kim, H.S.; Yoo, H.S. Surface-polymerized biomimetic nanofibrils for the cell-directed association of 3-D scaffolds. Chemical Communications, 2014, 51, 306–309. doi: 10.1039/c4cc06875k
  13. Guo, Y.; Yuan, H.; Claudio, N.M.; Kura, S.; Shakerdge, N.; Mempel, T.R.; Bacskai, B.J.; Josephson, L. PEG-Like Nanoprobes: Multimodal, Pharmacokinetically and Optically Tunable Nanomaterials. PLoS ONE, 2014, 9(4), e95406. doi: 10.1371/journal.pone.0095406
  14. Al-Hilal, T.A.; Alam, F.; Park, J.W.; Kim, K.; Kwon, I.C.; Ryu, G.H.; Byun, Y. Prevention effect of orally active heparin conjugate on cancer-associated thrombosis. Journal of Controlled Release, 2014, 195, 155-161. doi: 10.1016/j.jconrel.2014.05.027
  15. Lin, Y.-A.; Cheetham, A.G.; Zhang, P.; Ou, Y.-C.; Li, Y.; Liu, G.; Hermida Merino, D.; Hamley, I.W.; Cui, H. Multi-Walled Nanotubes Formed by Catanionic Mixtures of Drug Amphiphiles. ACS Nano, 2014, 8(12), 12690-12700. doi: 10.1021/nn505688b
  16. Ayala-Orozco, C.; Liu, J.G.; Knight, M.W.; Wang, Y.; Day, J.K.; Nordlander, P.; Halas, N.J. Fluorescence Enhancement of Molecules Inside a Gold Nanomatryoshka. Nano Letters, 2014, 14(5), 2926-2933. doi: 10.1021/nl501027j
  17. Bříza, T.; Rimpelová, S.; Králová, J.; Záruba, K.; Kejík, Z.; Ruml, T.; Martásek, P.; Král, V. Pentamethinium fluorescent probes: The impact of molecular structure on photophysical properties and subcellular localization. Dyes and Pigments, 2014, 107, 51-59. doi: 10.1016/j.dyepig.2013.12.021
  18. Bamrungsap, S.; Apiwat, C.; Chantima, W.; Dharakul, T.; Wiriyachaiporn, N. Rapid and sensitive lateral flow immunoassay for influenza antigen using fluorescently-doped silica nanoparticles. Microchimica Acta, 2014, 181(1–2), 223-230. doi: 10.1007/s00604-013-1106-4
  19. Brady, M.L.; Raghavan, R.; Singh, D.; Anand, P.; Fleisher, A.S.; Mata, J.; Broaddus, W.C.; Olbricht, W.L. In vivo performance of a microfabricated catheter for intraparenchymal delivery. Journal of Neuroscience Methods, 2014, 229, 76-83. doi: 10.1016/j.jneumeth.2014.03.016
  20. Brand, C.; Abdel-Atti, D.; Zhang, Y.; Carlin, S.; Clardy, S.M.; Keliher, E.J.; Weber, W.A.; Lewis, J.S.; Reiner, T. In Vivo Imaging of GLP-1R with a Targeted Bimodal PET/Fluorescence Imaging Agent. Bioconjugate Chemistry, 2014, 25(7), 1323-1330. doi: 10.1021/bc500178d
  21. Bruckman, M.A.; Randolph, L.N.; VanMeter, A.; Hern, S.; Shoffstall, A.J.; Taurog, R.E.; Steinmetz, N.F. Biodistribution, pharmacokinetics, and blood compatibility of native and PEGylated tobacco mosaic virus nano-rods and -spheres in mice. Virology, 2014, 449, 163-173. doi: 10.1016/j.virol.2013.10.035
  22. Bruckman, M.A.; Steinmetz, N.F. Chemical Modification of the Inner and Outer Surfaces of Tobacco Mosaic Virus (TMV). Methods in Molecular Biology (Virus Hybrids as Nanomaterials), 2014, 1108, 173-185. doi: 10.1007/978-1-62703-751-8_13
  23. Burnham-Marusich, A.R.; Plechaty, A.M.; Berninsone, P.M. Size-matched alkyne-conjugated cyanine fluorophores to identify differences in protein glycosylation. Electrophoresis, 2014, 35(18), 2621-2625. doi: 10.1002/elps.201400241
  24. Duellberg, C.; Trokter, M.; Jha, R.; Sen, I.; Steinmetz, M.O.; Surrey, T. Reconstitution of a hierarchical +TIP interaction network controlling microtubule end tracking of dynein. Nature Cell Biology, 2014, 16(8), 804-811. doi: 10.1038/ncb2999
  25. Feret, R.; Lilley, K.S. Protein Profiling Using Two-Dimensional Difference Gel Electrophoresis (2-D DIGE). Current Protocols in Protein Science, 2014, 22.2.1-22.2.17. doi: 10.1002/0471140864.ps2202s75
  26. Geertsema, H.J.; Kulczyk, A.W.; Richardson, C.C.; van Oijen, A.M. Single-molecule studies of polymerase dynamics and stoichiometry at the bacteriophage T7 replication machinery. Proceedings of the National Academy of Sciences of the U.S.A., 2014, 111(11), 4073-4078. doi: 10.1073/pnas.1402010111
  27. Graen, T.M.D.; Hoefling, M.; Grubmüller, H. AMBER-DYES: Characterization of Charge Fluctuations and Force Field Parameterization of Fluorescent Dyes for Molecular Dynamics Simulations. Journal of Chemical Theory and Computation, 2014, 10(12), 5505-5512. doi: 10.1021/ct500869p
  28. Hatzenpichler, R.; Scheller, S.; Tavormina, P.L.; Babin, B.M.; Tirrell, D.A.; Orphan, V.J. In situ visualization of newly synthesized proteins in environmental microbes using amino acid tagging and click chemistry. Environmental Microbiology, 2014, 16(8), 2568-2590. doi: 10.1111/1462-2920.12436
  29. Hong, T.N.; van der Hoorn, R.A.L. DIGE-ABPP by Click Chemistry: Pairwise Comparison of Serine Hydrolase Activities from the Apoplast of Infected Plants. Plant-Pathogen Interactions (Methods in Molecular Biology), 2014, 1127, 183-194. doi: 10.1007/978-1-62703-986-4_15
  30. Hu, S.-H.; Fang, R.-H.; Chen, Y.-W.; Liao, B.-J.; Chen, I.-W.; Chen, S.-Y. Photoresponsive Protein-Graphene-Protein Hybrid Capsules with Dual Targeted Heat-Triggered Drug Delivery Approach for Enhanced Tumor Therapy. Advanced Functional Materials, 2014, 24(26), 4144-4155. doi: 10.1002/adfm.201400080
  31. Hu, X.; Wang, Q.; Liu, Y.; Liu, H.; Qin, C.; Cheng, K.; Robinson, W.; Gray, B.D.; Pak, K.Y.; Yu, A. et al. Optical imaging of articular cartilage degeneration using near-infrared dipicolylamine probes. Biomaterials, 2014, 35(26), 7511-7521. doi: 10.1016/j.biomaterials.2014.05.042
  32. Kim, J.; Yang, Y.; Song, S.S.; Na, J.-H.; Oh, K.J.; Jeong, C.; Yu, Y.G.; Shin, Y.-K. Beta-Amyloid Oligomers Activate Apoptotic BAK Pore for Cytochrome c Release. Biophysical Journal, 2014, 107(7), 1601-1608. doi: 10.1016/j.bpj.2014.07.074
  33. Kim, K.S.; Park, W.; Hu, J.; Bae, Y.H.; Na, K. A cancer-recognizable MRI contrast agents using pH-responsive polymeric micelle. Biomaterials, 2014, 35(1), 337-343. doi: 10.1016/j.biomaterials.2013.10.004
  34. Kupryushkin, M.S.; Nekrasov, M.D.; Stetsenko, D.A.; Pyshnyi, D.V. Efficient Functionalization of Oligonucleotides by New Achiral Nonnucleosidic Monomers. Organic Letters, 2014, 16(11), 2842-2845. doi: 10.1021/ol500668n
  35. Li, G.; Xing, Y.; Wang, J.; Conti, P.S.; Chen, K. Near-infrared fluorescence imaging of CD13 receptor expression using a novel Cy5.5-labeled dimeric NGR peptide. Amino Acids, 2014, 46(6), 1547-1556. doi: 10.1007/s00726-014-1727-x
  36. Li, L.-L.; Xu, J.-H.; Qi, G.-B.; Zhao, X.; Yu, F.; Wang, H. Core-Shell Supramolecular Gelatin Nanoparticles for Adaptive and "On-Demand" Antibiotic Delivery. ACS Nano, 2014, 8(5), 4975-4983. doi: 10.1021/nn501040h
  37. Lin, W.; Liu, J.; Jeffries, C.; Yang, L.; Lu, Y.; Lee, R.E.; Chen, T. Development of BODIPY FL Vindoline as a Novel and High-Affinity Pregnane X Receptor Fluorescent Probe. Bioconjugate Chemistry, 2014, 25(9), 1664-1677. doi: 10.1021/bc5002856
  38. Lin, X.; Zhu, H.; Luo, Z.; Hong, Y.; Zhang, H.; Liu, X.; Ding, H.; Tian, H.; Yang, Z. Near-Infrared Fluorescence Imaging of Non-Hodgkin's Lymphoma CD20 Expression Using Cy7-Conjugated Obinutuzumab. Molecular Imaging and Biology, 2014. doi: 10.1007/s11307-014-0742-3
  39. Lv, S.; Tang, Z.; Li, M.; Lin, J.; Song, W.; Liu, H.; Huang, Y.; Zhang, Y.; Chen, X. Co-delivery of doxorubicin and paclitaxel by PEG-polypeptide nanovehicle for the treatment of non-small cell lung cancer. Biomaterials, 2014, 35(23), 6118-6129. doi: 10.1016/j.biomaterials.2014.04.034
  40. Ma, X.; Cheng, Z.; Jin, Y.; Liang, X.; Yang, X.; Dai, Z.; Tian, J. SM5-1-Conjugated PLA nanoparticles loaded with 5-fluorouracil for targeted hepatocellular carcinoma imaging and therapy. Biomaterials, 2014, 35(9), 2878-2889. doi: 10.1016/j.biomaterials.2013.12.045
  41. Morton, S.W.; Lee, M.J.; Deng, Z.J.; Dreaden, E.C.; Siouve, E.; Shopsowitz, K.E.; Shah, N.J.; Yaffe, M.B.; Hammond, P.T. A Nanoparticle-Based Combination Chemotherapy Delivery System for Enhanced Tumor Killing by Dynamic Rewiring of Signaling Pathways. Science Signaling, 2014, 7(325), ra44-ra44. doi: 10.1126/scisignal.2005261
  42. Morton, S.W.; Zhao, X.; Quadir, M.A.; Hammond, P.T. FRET-enabled biological characterization of polymeric micelles. Biomaterials, 2014, 35(11), 3489-3496. doi: 10.1016/j.biomaterials.2014.01.027
  43. Nienhaus, L.; Gross, D.E.; Xue, Z.; Moore, J.S.; Gruebele, M. Intramolecular energy transfer in a synthetic dendron-based light harvesting system. Journal of Photochemistry and Photobiology A: Chemistry, 2014, 295, 26-33. doi: 10.1016/j.jphotochem.2014.08.014
  44. Nobori, T.; Shiosaki, S.; Mori, T.; Toita, R.; Kim, C.W.; Nakamura, Y.; Kishimura, A.; Niidome, T.; Katayama, Y. Fluorescent Polyion Complex Nanoparticle That Incorporates an Internal Standard for Quantitative Analysis of Protein Kinase Activity. Bioconjugate Chemistry, 2014, 25(5), 869-872. doi: 10.1021/bc500142j
  45. Novo, L.; Rizzo, L.Y.; Golombek, S.K.; Dakwar, G.R.; Lou, B.; Remaut, K.; Mastrobattista, E.; van Nostrum, C.F.; Jahnen-Dechent, W.; Kiessling, F. et al. Decationized polyplexes as stable and safe carrier systems for improved biodistribution in systemic gene therapy. Journal of Controlled Release, 2014, 195, 162-175. doi: 10.1016/j.jconrel.2014.08.028
  46. Palsuledesai, C.C.; Ochocki, J.D.; Markowski, T.W.; Distefano, M.D. A combination of metabolic labeling and 2D-DIGE analysis in response to a farnesyltransferase inhibitor facilitates the discovery of new prenylated proteins. Molecular BioSystems, 2014, 10(5), 1094-1103. doi: 10.1039/c3mb70593e
  47. Park, S.; Kim, Y.-J.; Jon, S. A high-affinity peptide for nicotinic acetylcholine receptor-α1 and its potential use in pulmonary drug delivery. Journal of Controlled Release, 2014, 192, 141-147. doi: 10.1016/j.jconrel.2014.07.006
  48. Rand, M.D.; Montgomery, S.L.; Prince, L.; Vorojeikina, D. Developmental Toxicity Assays Using the Drosophila Model. Current Protocols in Toxicology, 2014, 1.12.1-1.12.20. doi: 10.1002/0471140856.tx0112s59
  49. Schulze, R.J.; Komar, J.; Botte, M.; Allen, W.J.; Whitehouse, S.; Gold, V.A.M.; Lycklama a Nijeholt, J.A.; Huard, K.; Berger, I.; Schaffitzel, C. et al. Membrane protein insertion and proton-motive-force-dependent secretion through the bacterial holo-translocon SecYEG-SecDF-YajC-YidC. Proceedings of the National Academy of Sciences of the U.S.A., 2014, 111(13), 4844-4849. doi: 10.1073/pnas.1315901111
  50. Shebl, B.; Norman, Z.; Cornish, P.V. Ribosome Structure and Dynamics by smFRET Microscopy. Methods in Enzymology, 2014, 549, 375-406. doi: 10.1016/b978-0-12-801122-5.00016-7
  51. Stuart, C.H.; Horita, D.A.; Thomas, M.J.; Salsbury, F.R.; Lively, M.O.; Gmeiner, W.H. Site-Specific DNA-Doxorubicin Conjugates Display Enhanced Cytotoxicity to Breast Cancer Cells. Bioconjugate Chemistry, 2014, 25(2), 406-413. doi: 10.1021/bc4005427
  52. Teske, N.S.; Voigt, J.; Shastri, V.P. Clickable Degradable Aliphatic Polyesters via Copolymerization with Alkyne Epoxy Esters: Synthesis and Postfunctionalization with Organic Dyes. Journal of the American Chemical Society, 2014, 136(29), 10527-10533. doi: 10.1021/ja505629w
  53. Ullrich, M.; Liang, V.; Chew, Y.L.; Banister, S.; Song, X.; Zaw, T.; Lam, H.; Berber, S.; Kassiou, M.; Nicholas, H.R. et al. Bio-orthogonal labeling as a tool to visualize and identify newly synthesized proteins in Caenorhabditis elegans. Nature Protocols, 2014, 9(9), 2237-2255. doi: 10.1038/nprot.2014.150
  54. Viehweger, K.; Barbaro, L.; García, K.P.; Joshi, T.; Geipel, G.; Steinbach, J.; Stephan, H.; Spiccia, L.; Graham, B. EGF Receptor-Targeting Peptide Conjugate Incorporating a Near-IR Fluorescent Dye and a Novel 1,4,7-Triazacyclononane-Based 64Cu(II) Chelator Assembled via Click Chemistry. Bioconjugate Chemistry, 2014, 25(5), 1011-1022. doi: 10.1021/bc5001388
  55. Wang, W.; Ji, X.; Na, H.B.; Safi, M.; Smith, A.; Palui, G.; Perez, J.M.; Mattoussi, H. Design of a Multi-Dopamine-Modified Polymer Ligand Optimally Suited for Interfacing Magnetic Nanoparticles with Biological Systems. Langmuir, 2014, 30(21), 6197-6208. doi: 10.1021/la500974r
  56. Wang, X.; Yang, Y.; Jia, H.; Jia, W.; Miller, S.; Bowman, B.; Feng, J.; Zhan, F. Peptide decoration of nanovehicles to achieve active targeting and pathology-responsive cellular uptake for bone metastasis chemotherapy. Biomaterials Science, 2014, 2(7), 961-971. doi: 10.1039/c4bm00020j
  57. Xie, M.; Xu, Y.; Shen, H.; Shen, S.; Ge, Y.; Xie, J. Negative-charge-functionalized mesoporous silica nanoparticles as drug vehicles targeting hepatocellular carcinoma. International Journal of Pharmaceutics, 2014, 474, 223-231. doi: 10.1016/j.ijpharm.2014.08.027
  58. Zhang, R.; Yang, J.; Sima, M.; Zhou, Y.; Kopeček, J. Sequential combination therapy of ovarian cancer with degradable N-(2-hydroxypropyl)methacrylamide copolymer paclitaxel and gemcitabine conjugates. Proceedings of the National Academy of Sciences of the U.S.A., 2014, 111(33), 12181-12186. doi: 10.1073/pnas.1406233111
  59. Zhang, Y.; Ge, C.; Zhu, C.; Salaita, K. DNA-based digital tension probes reveal integrin forces during early cell adhesion. Nature Communications, 2014, 5, 5167-5167. doi: 10.1038/ncomms6167
  60. Zhao, Y.; Meek, G.A.; Levine, B.G.; Lunt, R.R. Near-Infrared Harvesting Transparent Luminescent Solar Concentrators. Advanced Optical Materials, 2014, 2(7), 606-611. doi: 10.1002/adom.201400103
  61. Zhou, Y.; Guo, T.; Tang, G.; Wu, H.; Wong, N.-K.; Pan, Z. Site-Selective Protein Immobilization by Covalent Modification of GST Fusion Proteins. Bioconjugate Chemistry, 2014, 25(11), 1911-1915. doi: 10.1021/bc500347b
  62. Zou, Y.; Li, F.; Hou, W.; Sampath, P.; Zhang, Y.; Thorne, S.H. Manipulating the expression of chemokine receptors enhances delivery and activity of cytokine-induced killer cells. British Journal of Cancer, 2014, 110(8), 1992-1999. doi: 10.1038/bjc.2014.140
  63. Chen, H.; Xiao, L.; Anraku, Y.; Mi, P.; Liu, X.; Cabral, H.; Inoue, A.; Nomoto, T.; Kishimura, A.; Nishiyama, N. et al. Polyion Complex Vesicles for Photoinduced Intracellular Delivery of Amphiphilic Photosensitizer. Journal of the American Chemical Society, 2014, 136(1), 157-163. doi: 10.1021/ja406992w

2013

  1. Joshi, R.; Feldmann, V.; Koestner, W.; Detje, C.; Gottschalk, S.; Mayer, H.A.; Sauer, M.G.; Engelmann, J. Multifunctional silica nanoparticles for optical and magnetic resonance imaging. Biological Chemistry, 2013, 394(1), 125–135. doi: 10.1515/hsz-2012-0251
  2. Skaat, H.; Corem-Salkmon, E.; Grinberg, I.; Last, D.; Goez, D.; Mardor, Y.; Margel, S. Antibody-conjugated, dual-modal, near-infrared fluorescent iron oxide nanoparticles for antiamyloidgenic activity and specific detection of amyloid-β fibrils. International Journal of Nanomedicine, 2013, 8, 4063–4076. doi: 10.2147/ijn.s52833
  3. Myung, J.-K.; Banuelos, C.A.; Fernandez, J.G.; Mawji, N.R.; Wang, J.; Tien, A.H.; Yang, Y.C.; Tavakoli, I.; Haile, S.; Watt, K.; McEwan, I.J.; Plymate, S.; Andersen, R.J.; Sadar, M.D. An androgen receptor N-terminal domain antagonist for treating prostate cancer. Journal of Clinical Investigation, 2013, 123(7), 2948–2960. doi: 10.1172/jci66398
  4. Chan, L.J.; Smith, C.M.; Chua, B.E.; Lin, F.; Bathgate, R.A.D.; Separovic, F.; Gundlach, A.L.; Hossain, M.A.; Wade, J.D. Synthesis of fluorescent analogs of relaxin family peptides and their preliminary in vitro and in vivo characterization. Frontiers in Chemistry, 2013, 1, Article 30. doi: 10.3389/fchem.2013.00030
  5. Petkau-Milroy, K.; Sonntag, M.; Colditz, A.; Brunsveld, L. Multivalent Protein Assembly Using Monovalent Self-Assembling Building Blocks. International Journal of Molecular Sciences, 2013, 14(10), 21189–21201. doi: 10.3390/ijms141021189
  6. Lee, A.; Chin, J.; Park, O.K.; Chung, H.; Kim, J.W.; Yoon, S.-Y.; Park, K. A novel near-infrared fluorescence chemosensor for copper ion detection using click ligation and energy transfer. Chemical Communications, 2013, 49, 5969–5971. doi: 10.1039/c3cc42059k
  7. Shabanpoor, F.; Gait, M.J. Development of a general methodology for labelling peptide–morpholino oligonucleotide conjugates using alkyne–azide click chemistry. Chemical Communications, 2013, 49, 10260–10262. doi: 10.1039/c3cc46067c
  8. Jain, D.; Siede, W. Rad5 Template Switch Pathway of DNA Damage Tolerance Determines Synergism between Cisplatin and NSC109268 in Saccharomyces cerevisiae. PLoS ONE, 2013, 8(10), e77666. doi: 10.1371/journal.pone.0077666
  9. Lee, S.; Ashizawa, A.T.; Kim, K.S.; Falk, D.J.; Notterpek, L. Liposomes to Target Peripheral Neurons and Schwann Cells. PLoS ONE, 2013, 8(11), e78724. doi: 10.1371/journal.pone.0078724
  10. Albertazzi, L.; Martinez-Veracoechea, F.J.; Leenders, C.M.A.; Voets, I.K.; Frenkel, D.; Meijer, E.W. Spatiotemporal control and superselectivity in supramolecular polymers using multivalency. Proceedings of the National Academy of Sciences of the U.S.A., 2013, 110(30), 12203-12208. doi: 10.1073/pnas.1303109110
  11. Aldeek, F.; Muhammed, M.A.H.; Palui, G.; Zhan, N.; Mattoussi, H. Growth of Highly Fluorescent Polyethylene Glycol- and Zwitterion-Functionalized Gold Nanoclusters. ACS Nano, 2013, 7(3), 2509-2521. doi: 10.1021/nn305856t
  12. Astakhova, I.K.; Hansen, L.H.; Vester, B.; Wengel, J. Peptide-LNA oligonucleotide conjugates. Organic & Biomolecular Chemistry, 2013, 11(25), 4240-4240. doi: 10.1039/c3ob40786a
  13. Astakhova, I.K.; Santhosh Kumar, T.; Campbell, M.A.; Ustinov, A.V.; Korshun, V.A.; Wengel, J. Branched DNA nanostructures efficiently stabilised and monitored by novel pyrene-perylene 2'-alpha-L-amino-LNA FRET pairs. Chemical Communications, 2013, 49(5), 511-511. doi: 10.1039/c2cc37547h
  14. Astakhova, I.K.; Wengel, J. Interfacing Click Chemistry with Automated Oligonucleotide Synthesis for the Preparation of Fluorescent DNA Probes Containing Internal Xanthene and Cyanine Dyes. Chemistry - a European Journal, 2013, 19(3), 1112-1122. doi: 10.1002/chem.201202621
  15. Cao, Z.; Partyka, K.; McDonald, M.; Brouhard, E.; Hincapie, M.; Brand, R.E.; Hancock, W.S.; Haab, B.B. Modulation of Glycan Detection on Specific Glycoproteins by Lectin Multimerization. Analytical Chemistry, 2013, 85(3), 1689-1698. doi: 10.1021/ac302826a
  16. Chang, Y.; Cai, C.; Li, L.; Miao, J.; Ucakturk, E.; Li, G.; Ly, M.; Linhardt, R.J. Ultrasensitive Detection and Quantification of Acidic Disaccharides Using Capillary Electrophoresis and Quantum Dot-Based Fluorescence Resonance Energy Transfer. Analytical Chemistry, 2013, 85(19), 9356-9362. doi: 10.1021/ac402242v
  17. Cheng, M.-C.; Leske, A.T.; Matsuoka, T.; Kim, B.C.; Lee, J.; Burns, M.A.; Takayama, S.; Biteen, J.S. Super-Resolution Imaging of PDMS Nanochannels by Single-Molecule Micelle-Assisted Blink Microscopy. The Journal of Physical Chemistry B, 2013, 117(16), 4406-4411. doi: 10.1021/jp307635v
  18. Damayanti, N.P.; Parker, L.L.; Irudayaraj, J.M.K. Fluorescence Lifetime Imaging of Biosensor Peptide Phosphorylation in Single Live Cells. Angewandte Chemie International Edition, 2013, 52(14), 3931-3934. doi: 10.1002/anie.201209303
  19. Gluz, E.; Grinberg, I.; Corem-Salkmon, E.; Mizrahi, D.; Margel, S. Engineering of new crosslinked near-infrared fluorescent polyethylene glycol bisphosphonate nanoparticles for bone targeting. Journal of Polymer Science, Part A: Polymer Chemistry, 2013, 51(20), 4282-4291. doi: 10.1002/pola.26858
  20. Gluz, E.; Mizrahi, D.M.; Margel, S. Synthesis and characterization of new poly(ethylene glycol)bisphosphonate vinylic monomer and non-fluorescent and NIR-fluorescent bisphosphonate micrometer-sized particles. Polymer, 2013, 54(2), 565-571. doi: 10.1016/j.polymer.2012.11.071
  21. Haller, A.; Altman, R.B.; Souliere, M.F.; Blanchard, S.C.; Micura, R. Folding and ligand recognition of the TPP riboswitch aptamer at single-molecule resolution. Proceedings of the National Academy of Sciences of the U.S.A., 2013, 110(11), 4188-4193. doi: 10.1073/pnas.1218062110
  22. Hartley, M.D.; Schneggenburger, P.E.; Imperiali, B. Lipid bilayer nanodisc platform for investigating polyprenol-dependent enzyme interactions and activities. Proceedings of the National Academy of Sciences of the U.S.A., 2013, 110(52), 20863-20870. doi: 10.1073/pnas.1320852110
  23. He, H.; Chen, S.; Zhou, J.; Dou, Y.; Song, L.; Che, L.; Zhou, X.; Chen, X.; Jia, Y.; Zhang, J. et al. Cyclodextrin-derived pH-responsive nanoparticles for delivery of paclitaxel. Biomaterials, 2013, 34(21), 5344-5358. doi: 10.1016/j.biomaterials.2013.03.068
  24. Kaastrup, K.; Chan, L.; Sikes, H.D. Impact of Dissociation Constant on the Detection Sensitivity of Polymerization-Based Signal Amplification Reactions. Analytical Chemistry, 2013, 85(17), 8055-8060. doi: 10.1021/ac4018988
  25. Kim, J.; Seo, M.-H.; Lee, S.; Cho, K.; Yang, A.; Woo, K.; Kim, H.-S.; Park, H.-S. Simple and Efficient Strategy for Site-Specific Dual Labeling of Proteins for Single-Molecule Fluorescence Resonance Energy Transfer Analysis. Analytical Chemistry, 2013, 85(3), 1468-1474. doi: 10.1021/ac303089v
  26. Lee, B.-S.; Amano, T.; Wang, H.Q.; Pantoja, J.L.; Yoon, C.W.; Hanson, C.J.; Amatya, R.; Yen, A.; Black, K.L.; Yu, J.S. Reactive Oxygen Species Responsive Nanoprodrug to Treat Intracranial Glioblastoma. ACS Nano, 2013, 7(4), 3061-3077. doi: 10.1021/nn400347j
  27. Lu, H.D.; Soranno, D.E.; Rodell, C.B.; Kim, I.L.; Burdick, J.A. Secondary Photocrosslinking of Injectable Shear-Thinning Dock-and-Lock Hydrogels. Advanced Healthcare Materials, 2013, 2(7), 1028-1036. doi: 10.1002/adhm.201200343
  28. Lu, X.; Song, C.-X.; Szulwach, K.; Wang, Z.; Weidenbacher, P.; Jin, P.; He, C. Chemical Modification-Assisted Bisulfite Sequencing (CAB-Seq) for 5-Carboxylcytosine Detection in DNA. Journal of the American Chemical Society, 2013, 135(25), 9315-9317. doi: 10.1021/ja4044856
  29. Mohan, K.; Donavan, K.C.; Arter, J.A.; Penner, R.M.; Weiss, G.A. Sub-nanomolar Detection of Prostate-Specific Membrane Antigen in Synthetic Urine by Synergistic, Dual-Ligand Phage. Journal of the American Chemical Society, 2013, 135(20), 7761-7767. doi: 10.1021/ja4028082
  30. Morton, S.W.; Herlihy, K.P.; Shopsowitz, K.E.; Deng, Z.J.; Chu, K.S.; Bowerman, C.J.; DeSimone, J.M.; Hammond, P.T. Scalable Manufacture of Built-to-Order Nanomedicine: Spray-Assisted Layer-by-Layer Functionalization of PRINT Nanoparticles. Advanced Materials, 2013, 25(34), 4707-4713. doi: 10.1002/adma.201302025
  31. Potapova, I.; Eglin, D.; Laschke, M.W.; Bischoff, M.; Richards, R.G.; Moriarty, T.F. Two-step labeling of Staphylococcus aureus with Lysostaphin-Azide and DIBO-Alexa using click chemistry. Journal of Microbiological Methods, 2013, 92(1), 90-98. doi: 10.1016/j.mimet.2012.11.004
  32. Rimpelová, S.; Bříza, T.; Králová, J.; Záruba, K.; Kejík, Z.; Císařová, I.; Martásek, P.; Ruml, T.; Král, V. Rational Design of Chemical Ligands for Selective Mitochondrial Targeting. Bioconjugate Chemistry, 2013, 24(9), 1445-1454. doi: 10.1021/bc400291f
  33. Saxena, T.; Karumbaiah, L.; Gaupp, E.A.; Patkar, R.; Patil, K.; Betancur, M.; Stanley, G.B.; Bellamkonda, R.V. The impact of chronic blood-brain barrier breach on intracortical electrode function. Biomaterials, 2013, 34(20), 4703-4713. doi: 10.1016/j.biomaterials.2013.03.007
  34. Sellrie, F.; Graser, E.; Lenz, C.; Hillebrand, T.; Schenk, J.A. Specific DNA detection using antibody mediated fluorescencequenching. Biosensors and Bioelectronics, 2013, 42, 512-515. doi: 10.1016/j.bios.2012.10.055
  35. Shen, H.; Shi, H.; Xie, M.; Ma, K.; Li, B.; Shen, S.; Wang, X.; Jin, Y. Biodegradable chitosan/alginate BSA-gel-capsules for pH-controlled loading and release of doxorubicin and treatment of pulmonary melanoma. Journal of Materials Chemistry B, 2013, 1(32), 3906-3906. doi: 10.1039/c3tb20330a
  36. Sloniec, J.; Resch-Genger, U.; Hennig, A. Photophysics and Release Kinetics of Enzyme-Activatable Optical Probes Based on H-Dimerized Fluorophores on Self-Immolative Linkers. The Journal of Physical Chemistry B, 2013, 117(46), 14336-14344. doi: 10.1021/jp409388b
  37. Soulière, M.F.; Altman, R.B.; Schwarz, V.; Haller, A.; Blanchard, S.C.; Micura, R. Tuning a riboswitch response through structural extension of a pseudoknot. Proceedings of the National Academy of Sciences of the U.S.A., 2013, 110(35), E3256-E3264. doi: 10.1073/pnas.1304585110
  38. Tang, H.; Sampath, P.; Yan, X.; Thorne, S.H. Potential for enhanced therapeutic activity of biological cancer therapies with doxycycline combination. Gene Therapy, 2013, 20(7), 770-778. doi: 10.1038/gt.2012.96
  39. Wang, C.; Ravi, S.; Garapati, U.S.; Das, M.; Howell, M.; Mallela, J.; Alwarappan, S.; Mohapatra, S.S.; Mohapatra, S. Multifunctional chitosan magnetic-graphene (CMG) nanoparticles: a theranostic platform for tumor-targeted co-delivery of drugs, genes and MRI contrast agents. Journal of Materials Chemistry B, 2013, 1(35), 4396-4396. doi: 10.1039/c3tb20452a
  40. Xie, M.; Shi, H.; Li, Z.; Shen, H.; Ma, K.; Li, B.; Shen, S.; Jin, Y. A multifunctional mesoporous silica nanocomposite for targeted delivery, controlled release of doxorubicin and bioimaging. Colloids and Surfaces B: Biointerfaces, 2013, 110, 138-147. doi: 10.1016/j.colsurfb.2013.04.009
  41. Xie, M.; Shi, H.; Ma, K.; Shen, H.; Li, B.; Shen, S.; Wang, X.; Jin, Y. Hybrid nanoparticles for drug delivery and bioimaging: Mesoporous silica nanoparticles functionalized with carboxyl groups and a near-infrared fluorescent dye. Journal of Colloid and Interface Science, 2013, 395, 306-314. doi: 10.1016/j.jcis.2013.01.001
  42. Yang, H.; Mao, H.; Wan, Z.; Zhu, A.; Guo, M.; Li, Y.; Li, X.; Wan, J.; Yang, X.; Shuai, X. et al. Micelles assembled with carbocyanine dyes for theranostic near-infrared fluorescent cancer imaging and photothermal therapy. Biomaterials, 2013, 34(36), 9124-9133. doi: 10.1016/j.biomaterials.2013.08.022
  43. Yuan, H.; Cho, H.; Chen, H.H.; Panagia, M.; Sosnovik, D.E.; Josephson, L. Fluorescent and radiolabeled triphenylphosphonium probes for imaging mitochondria. Chemical Communications, 2013, 49(88), 10361-10363. doi: 10.1039/c3cc45802d
  44. Zhan, N.; Palui, G.; Safi, M.; Ji, X.; Mattoussi, H. Multidentate Zwitterionic Ligands Provide Compact and Highly Biocompatible Quantum Dots. Journal of the American Chemical Society, 2013, 135(37), 13786-13795. doi: 10.1021/ja405010v
  45. Zhou, Z.; Wu, X.; Kresak, A.; Griswold, M.; Lu, Z.-R. Peptide targeted tripod macrocyclic Gd(III) chelates for cancer molecular MRI. Biomaterials, 2013, 34(31), 7683-7693. doi: 10.1016/j.biomaterials.2013.06.057
  46. Zou, C.; Loka, R.S.; Zhang, Y.; Cairo, C.W. Glycoform Remodeling Generates a Synthetic T Cell Phenotype. Bioconjugate Chemistry, 2013, 24(6), 907-914. doi: 10.1021/bc300599w
  47. Xie, M.; Shi, H.; Ma, K.; Shen, H.; Li, B.; Shen, S.; Wang, X.; Jin, Y. Hybrid nanoparticles for drug delivery and bioimaging: Mesoporous silica nanoparticles functionalized with carboxyl groups and a near-infrared fluorescent dye. Journal of Colloid and Interface Science, 2013, 395, 306-314. doi: 10.1016/j.jcis.2013.01.001

2012

  1. Liboska, R.; Ligasová, A.; Strunin, D.; Rosenberg, I.; Koberna, K. Most Anti-BrdU Antibodies React with 2'-Deoxy-5-Ethynyluridine ‒ The Method for the Effective Suppression of This Cross-Reactivity. PLoS ONE, 2012, 7(12), e51679. doi: 10.1371/journal.pone.0051679
  2. Liu, Z.; Miller, S.J.; Joshi, B.P.; Wang, T.D. In vivo targeting of colonic dysplasia on fluorescence endoscopy with near-infrared octapeptide. Gut, 2012, 62(3), 395-403. doi: 10.1136/gutjnl-2011-301913
  3. Adulnirath, A.; Chung, S.W.; Park, J.; Hwang, S.R.; Kim, J.-Y.; Yang, V.C.; Kim, S.Y.; Moon, H.T.; Byun, Y. Cyclic RGDyk-conjugated LMWH-taurocholate derivative as a targeting angiogenesis inhibitor. Journal of Controlled Release, 2012, 164(1), 8-16. doi: 10.1016/j.jconrel.2012.10.001
  4. Fan, H.; Zhang, I.; Chen, X.; Zhang, L.; Wang, H.; Da Fonseca, A.; Manuel, E.R.; Diamond, D.J.; Raubitschek, A.; Badie, B. Intracerebral CpG Immunotherapy with Carbon Nanotubes Abrogates Growth of Subcutaneous Melanomas in Mice. Clinical Cancer Research, 2012, 18(20), 5628-5638. doi: 10.1158/1078-0432.ccr-12-1911
  5. Gatzogiannis, E.; Chen, Z.; Wei, L.; Wombacher, R.; Kao, Y.-T.; Yefremov, G.; Cornish, V.W.; Min, W. Mapping protein-specific micro-environments in live cells by fluorescence lifetime imaging of a hybrid genetic-chemical molecular rotor tag. Chemical Communications, 2012, 48(69), 8694-8694. doi: 10.1039/c2cc33133k
  6. Kaastrup, K.; Sikes, H.D. Polymerization-based signal amplification under ambient conditions with thirty-five second reaction times. Lab on a Chip, 2012, 12(20), 4055-4055. doi: 10.1039/c2lc40584a
  7. Kim, J.-y.; Shim, G.; Choi, H.-w.; Park, J.; Chung, S.W.; Kim, S.; Kim, K.; Chan Kwon, I.; Kim, C.-W.; Kim, S.Y. et al. Tumor vasculature targeting following co-delivery of heparin-taurocholate conjugate and suberoylanilide hydroxamic acid using cationic nanolipoplex. Biomaterials, 2012, 33(17), 4424-4430. doi: 10.1016/j.biomaterials.2012.02.066
  8. Kim, W.-J.; Kim, A.; Huh, C.; Park, C.W.; Ah, C.S.; Kim, B.K.; Yang, J.-H.; Chung, K.H.; Choi, Y.H.; Hong, J. et al. Photo selective protein immobilization using bovine serum albumin. Applied Surface Science, 2012, 261, 880-889. doi: 10.1016/j.apsusc.2012.08.111
  9. Kovacic, S.; Samii, L.; Woolfson, D.N.; Curmi, P.M.G.; Linke, H.; Forde, N.R.; Blab, G.A. Design and Construction of a One-Dimensional DNA Track for an Artificial Molecular Motor. Journal of Nanomaterials, 2012, 2012, ID-ID 109238. doi: 10.1155/2012/109238
  10. McGouran, J.F.; Kramer, H.B.; Mackeen, M.M.; di Gleria, K.; Altun, M.; Kessler, B.M. Fluorescence-based active site probes for profiling deubiquitinating enzymes. Organic & Biomolecular Chemistry, 2012, 10(17), 3379-3379. doi: 10.1039/c2ob25258a
  11. Meimetis, L.G.; Williams, D.E.; Mawji, N.R.; Banuelos, C.A.; Lal, A.A.; Park, J.J.; Tien, A.H.; Fernandez, J.G.; de Voogd, N.J.; Sadar, M.D. et al. Niphatenones, Glycerol Ethers from the Sponge Niphates digitalis Block Androgen Receptor Transcriptional Activity in Prostate Cancer Cells: Structure Elucidation, Synthesis, and Biological Activity . Journal of Medicinal Chemistry, 2012, 55(1), 503-514. doi: 10.1021/jm2014056
  12. Molinari, C.E.; Casadio, Y.S.; Hartmann, B.T.; Livk, A.; Bringans, S.; Arthur, P.G.; Hartmann, P.E. Proteome Mapping of Human Skim Milk Proteins in Term and Preterm Milk. Journal of Proteome Research, 2012, 11(3), 1696-1714. doi: 10.1021/pr2008797
  13. Pecqueur, L.; Duellberg, C.; Dreier, B.; Jiang, Q.; Wang, C.; Pluckthun, A.; Surrey, T.; Gigant, B.; Knossow, M. A designed ankyrin repeat protein selected to bind to tubulin caps the microtubule plus end. Proceedings of the National Academy of Sciences of the U.S.A., 2012, 109(30), 12011-12016. doi: 10.1073/pnas.1204129109
  14. Preus, S.; Wilhelmsson, L.M. Advances in Quantitative FRET-Based Methods for Studying Nucleic Acids. ChemBioChem, 2012, 13(14), 1990-2001. doi: 10.1002/cbic.201200400
  15. Sparks, J.; Slobodkin, G.; Matar, M.; Congo, R.; Ulkoski, D.; Rea-Ramsey, A.; Pence, C.; Rice, J.; McClure, D.; Polach, K.J. et al. Versatile cationic lipids for siRNA delivery. Journal of Controlled Release, 2012, 158(2), 269-276. doi: 10.1016/j.jconrel.2011.11.006
  16. Truong, F.; Yoo, T.H.; Lampo, T.J.; Tirrell, D.A. Two-Strain, Cell-Selective Protein Labeling in Mixed Bacterial Cultures. Journal of the American Chemical Society, 2012, 134(20), 8551-8556. doi: 10.1021/ja3004667
  17. Zhou, K.; Liu, H.; Zhang, S.; Huang, X.; Wang, Y.; Huang, G.; Sumer, B.D.; Gao, J. Multicolored pH-Tunable and Activatable Fluorescence Nanoplatform Responsive to Physiologic pH Stimuli. Journal of the American Chemical Society, 2012, 134(18), 7803-7811. doi: 10.1021/ja300176w
  18. Zolotarskaya, O.Y.; Wagner, A.F.; Beckta, J.M.; Valerie, K.; Wynne, K.J.; Yang, H. Synthesis of Water-Soluble Camptothecin-Polyoxetane Conjugates via Click Chemistry. Molecular Pharmaceutics, 2012, 9(11), 3403-3408. doi: 10.1021/mp3005066

2011

  1. Zhao, D.; Alizadeh, D.; Zhang, L.; Liu, W.; Farrukh, O.; Manuel, E.; Diamond, D.J.; Badie, B. Carbon Nanotubes Enhance CpG Uptake and Potentiate Antiglioma Immunity. Clinical Cancer Research, 2011, 17(4), 771–782. doi: 10.1158/1078-0432.ccr-10-2444
  2. Ranasinghe, R.T.; Brown, T. Ultrasensitive fluorescence-based methods for nucleic acid detection: towards amplification-free genetic analysis. Chemical Communications, 2011, 47(13), 3717-3735. doi: 10.1039/c0cc04215c
  3. Song, C.-X.; Sun, Y.; Dai, Q.; Lu, X.-Y.; Yu, M.; Yang, C.-G.; He, C. Detection of 5-Hydroxymethylcytosine in DNA by Transferring a Keto-Glucose by Using T4 Phage beta-Glucosyltransferase. ChemBioChem, 2011, 12(11), 1682-1685. doi: 10.1002/cbic.201100278
  4. Song, C.-X.; Yu, M.; Dai, Q.; He, C. Detection of 5-hydroxymethylcytosine in a combined glycosylation restriction analysis (CGRA) using restriction enzyme Taq[alpha]I. Bioorganic & Medicinal Chemistry Letters, 2011, 21(17), 5075-5077. doi: 10.1016/j.bmcl.2011.03.118

2010

  1. Paredes, E.; Das, S.R. Click Chemistry for Rapid Labeling and Ligation of RNA. ChemBioChem, 2010, 12(1), 125-131. doi: 10.1002/cbic.201000466
  2. Ranall, M.; Gabrielli, B.; Gonda, T. Adaptation and validation of DNA synthesis detection by fluorescent dye derivatization for high-throughput screening. BioTechniques, 2010, 48(5), 379-386. doi: 10.2144/000113410
Товар добавлен. Просмотрите корзину покупок или оформите заказ
Введено некорректное число товаров для добавления.